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prediction of preterm delivery

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https://www.readbyqxmd.com/read/29684382/maternal-plasma-concentrations-of-macrophage-migration-inhibitory-factor-at-first-trimester-as-a-predictive-biomarker-of-preterm-delivery-in-chinese-women
#1
Hui Zhu, Mei-Jun Yang
BACKGROUND: Infection and/or inflammation have been proposed play role in the preterm delivery (PTD) pathogenesis. Macrophage migration inhibitory factor(MIF), a mediator of innate immunity and inflammation, is induced in various infections, including those that occur during pregnancy. We assessed the relation between maternal early pregnancy plasma concentrations of MIF and PTD. METHODS: Women were recruited before 14 weeks gestation and were followed up until delivery...
April 20, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29680471/the-neu-prem-trial-neuromonitoring-of-brains-of-infants-born-preterm-during-resuscitation-a-prospective-observational-cohort-study
#2
Anup C Katheria, M J Harbert, Sunil B Nagaraj, Kathy Arnell, Debra M Poeltler, Melissa K Brown, Wade Rich, Kasim O Hassen, Neil Finer
OBJECTIVE: To determine whether monitoring cerebral oxygen tissue saturation (StO2 ) with near-infrared spectroscopy (NIRS) and brain activity with amplitude-integrated electroencephalography (aEEG) can predict infants at risk for intraventricular hemorrhage (IVH) and death in the first 72 hours of life. STUDY DESIGN: A NIRS sensor and electroencephalography leads were placed on 127 newborns <32 weeks of gestational age at birth. Ten minutes of continuous NIRS and aEEG along with heart rate, peripheral arterial oxygen saturation, fraction of inspired oxygen, and mean airway pressure measurements were obtained in the delivery room...
April 16, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29671167/vitamin-d-deficiency-and-depressive-symptoms-in-pregnancy-are-associated-with-adverse-perinatal-outcomes
#3
Eynav Elgavish Accortt, Amy Lamb, James Mirocha, Calvin J Hobel
Prenatal vitamin D deficiency and prenatal depression are both separately associated with adverse perinatal outcomes; however, to our knowledge no studies have investigated the effects of having both risk factors. Our objective was to determine to what extent vitamin D deficiency predicts adverse perinatal outcomes and whether elevated depressive symptoms in pregnancy places women at additional increased risk. This study was a secondary data analysis of prospective data collected from a cohort of pregnant women (N = 101) in an obstetric clinic of a large medical center...
April 18, 2018: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29667359/predicting-responses-to-mechanical-ventilation-for-preterm-infants-with-acute-respiratory-illness-using-artificial-neural-networks
#4
Katharine Brigham, Samir Gupta, John C Brigham
Infants born prematurely are particularly susceptible to respiratory illness due to underdeveloped lungs, which can often result in fatality. Preterm infants in acute stages of respiratory illness typically require mechanical ventilation assistance, and the efficacy of the type of mechanical ventilation and its delivery has been the subject of a number clinical studies. With recent advances in machine learning approaches, particularly deep learning, it may be possible to estimate future responses to mechanical ventilation in real-time, based on ventilation monitoring up to the point of analysis...
April 17, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29665758/the-efficacy-of-adjunct-tacrolimus-treatment-in-pregnancy-outcomes-in-patients-with-systemic-lupus-erythematosus
#5
K Ichinose, S Sato, Y Kitajima, Y Horai, K Fujikawa, M Umeda, S Fukui, A Nishino, T Koga, S Y Kawashiri, N Iwamoto, M Tamai, H Nakamura, T Origuchi, I Yasuhi, H Masuzaki, A Kawakami
Systemic lupus erythematosus (SLE) involves multiple organ systems and primarily affects women during their reproductive years. Pregnancy in a woman with SLE may lead to higher rates of disease flares. Little is known regarding which medications are safe to maintain remission and/or treat flares throughout such pregnancies. Here we retrospectively analyzed the efficacy of tacrolimus (TAC) in the pregnancy outcomes of SLE patients. We studied the 54 deliveries of 40 SLE patients over an eight-year period from 2008 to 2016...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29663314/prediction-models-for-the-risk-of-spontaneous-preterm-birth-based-on-maternal-characteristics-a-systematic-review-and-independent-external-validation
#6
Linda Je Meertens, Pim van Montfort, Hubertina Cj Scheepers, Sander Mj van Kuijk, Robert Aardenburg, Josje Langenveld, Ivo Ma van Dooren, Iris M Zwaan, Marc Ea Spaanderman, Luc Jm Smits
INTRODUCTION: Prediction models may contribute to personalized risk-based management of women at high risk of spontaneous preterm delivery. Although prediction models are published frequently, often with promising results, external validation generally lacks. We performed a systematic review of prediction models for the risk of spontaneous preterm birth based on routine clinical parameters. Additionally, we externally validated and evaluated the clinical potential of the models. MATERIAL AND METHODS: Prediction models based on routinely collected maternal parameters obtainable during first 16 weeks of gestation were eligible for selection...
April 17, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29662967/maternal-serum-uric-acid-level-and-maternal-and-neonatal-complications-in-preeclamptic-women-a-cross-sectional-study
#7
Maryam Asgharnia, Fariba Mirblouk, Soudabeh Kazemi, Davood Pourmarzi, Mina Mahdipour Keivani, Seyedeh Fatemeh Dalil Heirati
Background: Preeclampsia is associated with maternal and neonatal complications. It has been indicated that increased uric acid might have a predictive role on preeclampsia. Objective: We aimed to investigate the relationship between the level of uric acid with maternal and neonatal complications in women with preeclampsia. Materials and Methods: In this cross-sectional study, 160 singleton preeclamptic women at more than 28 wk gestational age were included...
September 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29656690/maternal-blood-endotoxin-activity-in-pregnancies-complicated-by-preterm-premature-rupture-of-membranes
#8
Stefania Ronzoni, Rohan D'Souza, Oksana Shynlova, Stephen Lye, Kellie E Murphy
OBJECTIVE: To compare maternal blood endotoxin activity (EA) in women with preterm premature rupture of membranes (PPROM) with gestational age (GA) matched controls; to evaluate serial EA till birth in pPROM and its correlation with latency to delivery. METHODS: We followed singleton preterm pregnancies from admission with PPROM until birth. Uncomplicated, GA-matched pregnancies served as controls. Demographics, birth and neonatal outcomes were collected. EA (EAA™) was assessed serially in PPROM and at study entry in controls...
April 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29605711/fetal-cell-free-dna-fraction-in-maternal-plasma-for-the-prediction-of-hypertensive-disorders-of-pregnancy
#9
Nobuhiro Suzumori, Akihiko Sekizawa, Takeshi Ebara, Osamu Samura, Aiko Sasaki, Rina Akaishi, Seiji Wada, Haruka Hamanoue, Fumiki Hirahara, Haruna Izumi, Hideaki Sawai, Hiroaki Nakamura, Takahiro Yamada, Kiyonori Miura, Hideaki Masuzaki, Takahiro Yamashita, Takashi Okai, Yoshimasa Kamei, Akira Namba, Jun Murotsuki, Tomohiro Tanemoto, Akimune Fukushima, Kazufumi Haino, Shinya Tairaku, Keiichi Matsubara, Kazutoshi Maeda, Takashi Kaji, Masanobu Ogawa, Hisao Osada, Haruki Nishizawa, Yoko Okamoto, Takeshi Kanagawa, Aiko Kakigano, Michihiro Kitagawa, Masaki Ogawa, Shunichiro Izumi, Yukiko Katagiri, Naoki Takeshita, Yasuyo Kasai, Katsuhiko Naruse, Reiko Neki, Hisashi Masuyama, Maki Hyodo, Yukie Kawano, Takashi Ohba, Kiyotake Ichizuka, Takeshi Nagamatsu, Atsushi Watanabe, Nahoko Shirato, Junko Yotsumoto, Miyuki Nishiyama, Tatsuko Hirose, Haruhiko Sago
OBJECTIVE: The purpose of this study is to compare the fetal fractions during non-invasive prenatal testing (NIPT) in singleton pregnancies according to gestational age and maternal characteristics to evaluate the utility of this parameter for the prediction of pregnancy complications including gestational diabetes mellitus (GDM) and hypertensive disorders of pregnancy (HDP). STUDY DESIGN: This study was a multicenter prospective cohort study. The present data were collected from women whose NIPT results were negative...
March 26, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29577271/anatomic-relationship-of-internal-cervical-os-to-maternal-bladder-in-pregnancies-at-low-and-high-risk-of-preterm-delivery
#10
Daniel Faustin, Sabia Akbar, Tatiana Bihun, Erica Gomez, Derek Liang, Petr Itzhak, Ralph Ruggiero, Joylin Devadoss
Preterm delivery correlates with perinatal death and long-term neurologic sequelae in surviving newborns.1,3 Cervical changes demonstrated by transvaginal sonogram can help to predict preterm labor.3,4 Shalev et al.4 have reported on the position of the internal cervical os relative to the maternal bladder in prediction of preterm delivery. We did the present retrospective study to test the hypothesis that women at risk of preterm delivery are more likely to display a low-set internal cervical os than are those at low risk of preterm labor and delivery...
March 25, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29575304/performance-of-commercially-available-placental-growth-factor-tests-in-women-with-suspected-preterm-pre-eclampsia-the-compare-study
#11
F P McCarthy, C Gill, P T Seed, K Bramham, L C Chappell, A H Shennan
OBJECTIVE: To compare the performance of three PlGF-based kits in prediction of time to delivery within 14 days in women with suspected preterm pre-eclampsia prior to 35 weeks' gestation. METHODS: We conducted a retrospective analysis of samples collected from three prospective pregnancy cohort studies. Participants were pregnant women with suspected preterm pre-eclampsia recruited in tertiary maternity units in the UK and Ireland. Samples were analysed simultaneously according to manufacturer's directions...
March 25, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29574853/prevalence-and-predictive-factors-of-early-postpartum-diabetes-among-women-with-gestational-diabetes-in-a-single-center-cohort
#12
Ankia Coetzee, Deidre Mason, David R Hall, Magda Conradie
OBJECTIVE: To determine the prevalence of diabetes at 6-12 weeks postpartum among women with gestational diabetes mellitus (GDM), and to identify prenatal postpartum diabetes predictors. METHODS: In the present prospective cohort study, glucose statuses of consecutive women newly diagnosed with hyperglycemia during pregnancy were evaluated at 6-12 weeks postpartum between November 1, 2015, and November 1, 2016, at Tygerberg Hospital, Cape Town, South Africa. Women with known diabetes were excluded...
March 25, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29566566/combination-of-three-dimensional-ultrasound-measurement-of-foetal-adrenal-gland-enlargement-and-placental-alpha-microglobulin-1-for-the-prediction-of-the-timing-of-delivery-within-seven-days-in-women-with-threatened-preterm-labour-and-preterm-labour
#13
Monchai Santipap, Vorapong Phupong
The aim of this study was to predict the timing of delivery within seven days in singleton pregnant women with threatened preterm labour and preterm labour by using a three-dimensional (3D) ultrasound measurement of foetal adrenal gland volume enlargement, a foetal zone enlargement and cervicovaginal placental alpha microglobulin-1 (PAMG-1) test. This prospective cohort study included singleton pregnant women at 22-36+6  weeks of gestation who presented with threatened preterm labour and with preterm labour...
March 23, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29564310/fetal-doppler-to-predict-cesarean-delivery-for-non-reassuring-fetal-status-in-the-severe-small-for-gestational-age-fetuses-of-late-preterm-and-term
#14
Ji Hye Jo, Yong Hee Choi, Jeong Ha Wie, Hyun Sun Ko, In Yang Park, Jong Chul Shin
Objective: To evaluate the significance of fetal Doppler parameters in predicting adverse neonatal outcomes and the risk of cesarean delivery due to non-reassuring fetal status, in severe small for gestational age (SGA) fetuses of late preterm and term gestation. Methods: Fetal brain and umbilical artery (UmA) Doppler parameters of cerebroplacental ratio (CPR) and UmA pulsatility index (PI) were evaluated in a cohort of 184 SGA fetuses between 34 and 41 weeks gestational age, who were less than the 5th percentile...
March 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29554145/determining-gestational-age-and-preterm-birth-in-rural-guatemala-a-comparison-of-methods
#15
John R Weinstein, Lisa M Thompson, Anaité Díaz Artiga, Joe P Bryan, William E Arriaga, Saad B Omer, John P McCracken
BACKGROUND: Preterm birth is the leading cause of death among children <5 years of age. Accurate determination of prematurity is necessary to provide appropriate neonatal care and guide preventive measures. To estimate the most accurate method to identify infants at risk for adverse outcomes, we assessed the validity of two widely available methods-last menstrual period (LMP) and the New Ballard (NB) neonatal assessment-against ultrasound in determining gestational age and preterm birth in highland Guatemala...
2018: PloS One
https://www.readbyqxmd.com/read/29544927/pregnancy-and-newborn-outcomes-in-arrhythmogenic-right-ventricular-cardiomyopathy-dysplasia
#16
E Gandjbakhch, E Varlet, G Duthoit, V Fressart, P Charron, C Himbert, C Maupain, C Bordet, F Hidden-Lucet, J Nizard
INTRODUCTION: The prognosis of pregnancy in patients with Arrhythmogenic Right Ventricular Cardiomyopathy/dysplasia (ARVC/D) is poorly documented. The aim of this study is to assess the cardiac risks during pregnancy and the impact of ARVC/D on fetuses/neonates/children. METHODS: We included all ARVC/D women with a history of pregnancy from the ARVC/D Pitié-Salpêtrière registry. Cardiac and obstetrical events having occurred during pregnancy/delivery/post-partum periods and neonatal data/follow-up were collected...
May 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29537127/successful-pregnancy-outcomes-following-liver-transplantation-is-predicted-by-renal-function
#17
Tiong Y Lim, Enoka Gonsalkorala, Mary D Cannon, Stella Gabeta, Leonie Penna, Nigel D Heaton, Michael A Heneghan
BACKGROUND: Liver transplantation (LT) is a successful treatment for both acute liver failure and end-stage liver disease. The number of women of reproductive age undergoing LT is increasing. Pregnancy outcomes are favourable but there is still a lack of prognostic markers. We aimed to identify factors predictive of adverse pregnancy outcomes in LT recipients. METHODS: An analysis of all pregnancies occurring in LT recipients from 1989-2016 at King's College Hospital was performed...
March 14, 2018: Liver Transplantation
https://www.readbyqxmd.com/read/29536576/implementation-of-universal-screening-for-preterm-delivery-by-mid-trimester-cervical-length-measurement
#18
Athena P Souka, Ioannis Papastefanou, Athanasios Pilalis, Dimitrios Kassanos, George Papadopoulos
OBJECTIVES: To assess the feasibility and the results of introducing a policy of universal screening for preterm delivery. METHODS: Transvaginal sonography for cervical length (CL) measurement was performed at 20-24 weeks of gestation. Vaginal progesterone therapy was offered to women with CL ≤ 15mm. RESULTS: 10,969 singleton pregnancies were assessed. The decline rate was 1.32%. Spontaneous preterm delivery at less than 32 weeks (SPD32), less than 34 weeks (SPD34) and less than 37 weeks (SPD37) occurred in 0...
March 14, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29536574/comparison-of-diagnostic-accuracy-of-early-screening-for-pre-eclampsia-by-nice-guidelines-and-a-method-combining-maternal-factors-and-biomarkers-results-of-spree
#19
M Y Tan, D Wright, A Syngelaki, R Akolekar, S Cicero, D Janga, M Singh, E Greco, A Wright, K Maclagan, L C Poon, K H Nicolaides
OBJECTIVE: To test the hypothesis that the performance of first-trimester screening for pre-eclampsia (PE) by a method that uses Bayes' theorem to combine maternal factors with biomarkers is superior to that defined by current National Institute for Health and Care Excellence (NICE) guidelines. METHODS: This was a prospective multicenter study (screening program for pre-eclampsia (SPREE)) in seven National Health Service maternity hospitals in England, of women recruited between April and December 2016...
March 14, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29530044/uptake-of-intermittent-preventive-treatment-and-pregnancy-outcomes-health-facilities-and-community-surveys-in-ch%C3%A3-kw%C3%A3-district-southern-mozambique
#20
Paulo Arnaldo, Eduard Rovira-Vallbona, Jerónimo S Langa, Crizolgo Salvador, Pieter Guetens, Driss Chiheb, Bernardete Xavier, Luc Kestens, Sónia M Enosse, Anna Rosanas-Urgell
BACKGROUND: Malaria in pregnancy leads to serious adverse effects on the mother and the child and accounts for 75,000-200,000 infant deaths every year. Currently, the World Health Organization recommends intermittent preventive treatment of malaria in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) at each scheduled antenatal care (ANC) visit. This study aimed to assess IPTp-SP coverage in mothers delivering in health facilities and at the community. In addition, factors associated with low IPTp-SP uptake and malaria adverse outcomes in pregnancy were investigated...
March 12, 2018: Malaria Journal
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