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prediction of preterm delivery

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https://www.readbyqxmd.com/read/29216009/the-first-trimester-aneuploidy-biochemical-markers-in-ivf-icsi-patients-have-no-additional-benefit-compared-to-spontaneous-conceptions-in-the-prediction-of-pregnancy-complications
#1
Iwona Szymusik, Przemyslaw Kosinski, Katarzyna Kosinska-Kaczynska, Damian Warzecha, Anetta Karwacka, Bartosz Kaczynski, Miroslaw Wielgos
OBJECTIVES: The aim of this study was to determine if the levels of biochemical aneuploidy markers in in vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) pregnancies differ from those in spontaneous pregnancies and to verify if biochemical markers could predict pregnancy outcome in IVF/ICSI gestations. METHODS: This was a prospective observational study performed in a group of 551 patients who underwent a combined first trimester prenatal screening (ultrasound scan and serum markers)...
December 7, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29212398/prediction-of-neonatal-respiratory-distress-syndrome-via-pulmonary-artery-doppler-examination
#2
Barış Büke, Emre Destegül, Hatice Akkaya, Deniz Şİmşek, Mert Kazandi
OBJECTIVE: We aimed with this study to evaluate the role of pulmonary artery acceleration time to ejection time ratio (PATET) in the prediction of respiratory distress syndrome (RDS) in preterm neonates. MATERIALS AND METHODS: In this prospective cohort study, 105 singleton pregnant women with no congenital abnormalities and pregnancy complications who delivered before 37 weeks of gestational age were included. All of the patients underwent ultrasound examination to obtain fetal pulmonary artery Doppler 15 patients excluded from the study due to giving birth more than 3 days of ultrasound examination or inadequate Doppler measurements...
December 7, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29207782/prediction-of-delivery-in-women-with-threatening-preterm-labour-using-phosphorylated-insulin-like-growth-factor-binding-protein-1-and-cervical-length-using-transvaginal-ultrasound
#3
Amrita Kumari, Vandana Saini, P K Jain, Mamta Gupta
Introduction: Preterm delivery remains a challenge in Obstetrics as it is responsible for significant cause of perinatal morbidity and mortality. At present there is no standard test for prediction of preterm labour for timely referral to a center with NICU facilities. Aim: To evaluate the effectiveness of the cervical phosphorylated insulin like growth factor binding protein-1(phIGFBP-1), cervical length measurement and combination of phIGFBP-1 with cervical length for Predicting Preterm Labour (PTL)...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29183020/clinical-application-of-quantitative-foetal-fibronectin-for-the-prediction-of-preterm-birth-in-symptomatic-women
#4
Samara K Radford, Fabricio Da Silva Costa, Edward Araujo Júnior, Penelope M Sheehan
AIM: To evaluate the clinical application of the new Hologic quantitative foetal fibronectin (qfFN) bedside test for the prediction of spontaneous preterm birth (sPTB) in patients with symptoms suggestive of spontaneous threatened preterm labour (sPTL). METHODS: A prospective observational study with 154 pregnant women presenting signs and symptoms of sPTL was conducted. These women were subjected to a qfFN test between 22 and 35 weeks of gestation For each cut-off threshold, the ability to predict sPTB at within 14 days of conducting the test and <37 weeks was assessed by calculating the positive predictive value (PPV), negative predictive value (NPV), likelihood ratios, odds ratios, sensitivity, and specificity...
November 29, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/29175171/early-warning-system-hypertension-thresholds-to-predict-adverse-outcomes-in-pre-eclampsia-a-prospective-cohort-study
#5
Hannah L Nathan, Paul T Seed, Natasha L Hezelgrave, Annemarie De Greeff, Elodie Lawley, John Anthony, David R Hall, Wilhelm Steyn, Lucy C Chappell, Andrew H Shennan
OBJECTIVES: To evaluate the association between blood pressure (BP) measurements and adverse outcomes in women with pre-eclampsia. STUDY DESIGN: A prospective cohort study of women with pre-eclampsia admitted to three South African tertiary facilities. BP was measured using the CRADLE Vital Signs Alert (VSA), incorporated with a traffic light early warning system; green: systolic BP <140 mmHg and diastolic BP <90 mmHg, yellow: systolic BP 140-159 and/or diastolic BP 90-109 mmHg (but neither is above the upper threshold), red: systolic BP ≥160 mmHg and/or diastolic BP ≥110 mmHg...
November 21, 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29170495/first-trimester-vaginal-microbiome-diversity-a-potential-indicator-of-preterm-delivery-risk
#6
Mohammed Monzoorul Haque, Mitali Merchant, Pinna Nishal Kumar, Anirban Dutta, Sharmila S Mande
Preterm birth is a leading cause of global neonate mortality. Hospitalization costs associated with preterm deliveries present a huge economic burden. Existing physical/biochemical markers for predicting preterm birth risk are mostly suited for application at mid/late pregnancy stages, thereby leaving very short time (between diagnosis and delivery) for adopting appropriate intervention strategies. Recent studies indicating correlations between pre/full-term delivery and the composition of vaginal microbiota in pregnant women have opened new diagnostic possibilities...
November 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29163937/development-and-validation-of-a-simplified-algorithm-for-neonatal-gestational-age-assessment-protocol-for-the-alliance-for-maternal-newborn-health-improvement-amanhi-prospective-cohort-study
#7
Abdullah Baqui, Parvez Ahmed, Sushil Kanta Dasgupta, Nazma Begum, Mahmoodur Rahman, Nasreen Islam, Mohammad Quaiyum, Betty Kirkwood, Karen Edmond, Caitlin Shannon, Samuel Newton, Lisa Hurt, Fyezah Jehan, Imran Nisar, Atiya Hussain, Naila Nadeem, Muhammad Ilyas, Anita Zaidi, Sunil Sazawal, Saikat Deb, Arup Dutta, Usha Dhingra, Said Moh'd Ali, Davidson H Hamer, Katherine Ea Semrau, Marina Straszak-Suri, Caroline Grogan, Godfrey Bemba, Anne Cc Lee, Blair J Wylie, Alexander Manu, Sachiyo Yoshida, Rajiv Bahl
Objective: The objective of the Alliance for Maternal and Newborn Health Improvement (AMANHI) gestational age study is to develop and validate a programmatically feasible and simple approach to accurately assess gestational age of babies after they are born. The study will provide accurate, population-based rates of preterm birth in different settings and quantify the risks of neonatal mortality and morbidity by gestational age and birth weight in five South Asian and sub-Saharan African sites...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29162956/risk-assessment-at-11-14-week-antenatal-visit-a-tertiary-referral-center-experience-from-south-india
#8
Anusha Vellamkondu, Akhila Vasudeva, Rajeshwari G Bhat, Asha Kamath, Sapna V Amin, Lavanya Rai, Pratap Kumar
Background: Present study carried out in a tertiary referral hospital in South India attempts to determine the predictive value of integrated screening at 11-14-week antenatal visit. Objectives: To determine the detection rate of fetal abnormalities at 11-14 weeks and also to predict the placental dysfunction disorders based on early integrated evaluation. Method: Integrated screening performed on 440 women between 11 and 14 weeks, including detailed maternal history [medical history, bad obstetric history (BOH)], body mass index (BMI), mean arterial pressure (MAP), detailed ultrasound and maternal serum biochemistry as part of combined first-trimester screening for aneuploidy...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29128973/relevant-features-selection-for-automatic-prediction-of-preterm-deliveries-from-pregnancy-electrohysterograhic-ehg-records
#9
Nafissa Sadi-Ahmed, Baya Kacha, Hamza Taleb, Malika Kedir-Talha
In this study, we proposed an approach able to predict whether a pregnant woman with contractions would give birth earlier than expected (i.e., before the 37 (t h) week of gestation (WG)). It only processes non-invasive electrohysterographic (EHG) signals fully automatically without assistance of an expert or an additional medical system. We used term and preterm EHG signals of 30-minutes duration collected between the 27 (t h) and the 32 (n d) WG. Preterm deliveries (< 37W G) had occurred in average 4...
November 11, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29112664/placental-alpha-microglobulin-1-compared-with-fetal-fibronectin-to-predict-preterm-delivery-in-symptomatic-women
#10
Deborah A Wing, Sina Haeri, Angela C Silber, Cheryl K Roth, Carl P Weiner, Nelson C Echebiri, Albert Franco, Lanissa M Pappas, John D Yeast, Angelle A Brebnor, J Gerald Quirk, Aisling M Murphy, Louise C Laurent, Nancy T Field, Mary E Norton
OBJECTIVE: To compare the rapid bedside test for placental α microglobulin-1 with the instrumented fetal fibronectin test for prediction of imminent spontaneous preterm delivery among women with symptoms of preterm labor. METHODS: We conducted a prospective observational study on pregnant women with signs or symptoms suggestive of preterm labor between 24 and 35 weeks of gestation with intact membranes and cervical dilatation less than 3 cm. Participants were prospectively enrolled at 15 U...
November 3, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29096631/prediction-of-uncomplicated-pregnancies-in-obese-women-a-prospective-multicentre-study
#11
Matias C Vieira, Sara L White, Nashita Patel, Paul T Seed, Annette L Briley, Jane Sandall, Paul Welsh, Naveed Sattar, Scott M Nelson, Debbie A Lawlor, Lucilla Poston, Dharmintra Pasupathy
BACKGROUND: All obese pregnant women are considered at equal high risk with respect to complications in pregnancy and birth, and are commonly managed through resource-intensive care pathways. However, the identification of maternal characteristics associated with normal pregnancy outcomes could assist in the management of these pregnancies. The present study aims to identify the factors associated with uncomplicated pregnancy and birth in obese women, and to assess their predictive performance...
November 3, 2017: BMC Medicine
https://www.readbyqxmd.com/read/29091282/correlation-between-maternal-anxiety-reactivity-of-fetal-cerebral-circulation-to-auditory-stimulation-and-birth-outcome-in-normotensive-and-gestational-hypertensive-women
#12
Marina Vujović, Mirjana Sovilj, Ljiljana Jeličić, Miodrag Stokić, Darko Plećaš, Snežana Plešinac, Nadežda Nedeljković
This study investigated the correlation between maternal anxiety and blood flow changes through the fetal middle cerebral artery (MCA) after defined acoustic stimulation in 43 normotensive (C) and 40 gestational hypertensive (GH) subjects. Neonatal outcomes (gestational age at birth, Apgar score, birth weight) in the C and GH groups were analyzed. State (STAI-S) and trait (STAI-T) anxiety was assessed using Spielberger's questionnaire. The MCA blood flow was assessed once between 28 and 41 weeks of gestation using color Doppler ultrasound before and after application of defined acoustic stimulus...
November 1, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/29082782/how-do-maternal-factors-impact-preeclampsia-prediction-in-brazilian-population
#13
Karina Bilda de Castro Rezende, Antônio José Ledo Alves da Cunha, Cristos Pritsivelis, Edson Chaves Faleiro, Joffre Amim Junior, Rita Guérios Bornia
OBJECTIVE: To evaluate the impacts of maternal risk factors described by the Fetal Medicine Foundation's 2012 algorithm (FMF2012) in a Brazilian population. METHODS: All singleton pregnancies submitted to first-trimester preeclampsia (PE) screening using the FMF2012 algorithm were considered for study inclusion. Maternal factors, recorded via a patient questionnaire, were described and compared between PE outcome groups. A Gaussian regression model was derived to measure the effects of maternal factors, and to identify factors that contributed significantly (p < ...
November 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29080126/perinatal-periods-of-risk-analysis-disentangling-race-and-socioeconomic-status-to-inform-a-black-infant-mortality-community-action-initiative
#14
Catherine L Kothari, Camryn Romph, Terra Bautista, Debra Lenz
Objectives The goal of this study is to use Perinatal Periods of Risk (PPOR) analysis to differentiate broad areas of risk (Maternal-Health/Prematurity, Maternal Care, Newborn Care, and Infant Health) associated with being Black from those associated with being poor. Methods Phase I PPOR compared two target populations (Black women/infants and poor women/infants) against a gold standard reference group (White, non-Hispanic women, aged 20+ years with 13+ years of education), then against each other. Phase II PPOR further partitioned excess risk into (1) Very-low-birthweight-risk and (2) Birthweight-specific-mortality-risk and identified individual-level risk factors...
October 27, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29073805/comparison-of-the-effectiveness-of-a-pamg-1-test-and-standard-clinical-assessment-in-the-prediction-of-preterm-birth-and-reduction-of-unnecessary-hospital-admissions
#15
Ghassan Lotfi, Saima Faraz, Razan Nasir, Sreenisha Somini, Rasha M Abdeldayem, Raghunandini Koratkar, Nadia Alsawalhi, Abeer Ammar
PURPOSE: The purpose of this study is to first compare the performance of the PAMG-1 biomarker test to that of standard clinical assessment (SCA) for the risk assessment of spontaneous preterm delivery (sPTD) among women with symptoms of preterm labor (PTL) and then calculate the potential impact on unnecessary admission reduction. MATERIALS AND METHODS: Patients of gestational age 240/7-366/7 with PTL symptoms, cervical dilatation ≤3 cm, no intercourse within 24 h, and clinically intact membranes were recruited consecutively into this prospective observational study...
October 26, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29055117/can-neutrophil-to-lymphocyte-ratio-predict-late-onset-sepsis-in-preterm-infants
#16
Senem Alkan Ozdemir, Esra Arun Ozer, Ozkan Ilhan, Sumer Sutcuoglu
BACKGROUND: The neutrophil to lymphocyte ratio (NLR) is an easily accessible biomarker that has been reported to represent disease severity in adult trials. The aim of this study was to evaluate the relationship between culture positiveness and NLR in cases where the reason of sepsis was considered, and to foresight an idea about the active agents. METHODS: Preterm infants with birth weights ≤1500 g and/or ≤32 gestational weeks were eligible for this study...
October 21, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29054051/the-incidence-and-risk-factors-of-epilepsy-in-children-born-preterm-a-nationwide-register-study
#17
Mikko Hirvonen, Riitta Ojala, Päivi Korhonen, Paula Haataja, Kai Eriksson, Mika Gissler, Tiina Luukkaala, Outi Tammela
OBJECTIVES: The aim was to compare the incidence of epilepsy between very preterm (VP) (<32(+0) weeks), moderately preterm (MP) (32(+0)-33(+6) weeks), late preterm (LP) (34(+0)-36(+6) weeks) and term infants (≥37 weeks) and to establish and compare risk factors of epilepsy in these groups. METHODS: The national register study included all live born infants in Finland in 1991-2008. Excluding infants with missing gestational age, a total of 1,033,349 infants were included in the analysis and they were analyzed in four subgroups (VP, MP, LP and term) and three time periods (1991-1995, 1996-2001 and 2002-2008)...
October 14, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29053978/patterns-of-change-in-anxiety-and-depression-during-pregnancy-predict-preterm-birth
#18
Chelsea Doktorchik, Shahirose Premji, Donna Slater, Tyler Williamson, Suzanne Tough, Scott Patten
BACKGROUND: To determine whether changes in anxiety and depression during pregnancy influence the risk of having a preterm birth (PTB), and whether chronic stress modifies this relationship. METHODS: The data source for the current study is the All Our Babies prospective cohort (AOB). Anxiety and depression were measured at 17-24 weeks and again at 32-36 weeks' gestation using the Spielberg State Anxiety Scale and the Edinburgh Postnatal Depression Scale, respectively...
October 2, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29037543/amniopatch-treatment-for-preterm-premature-rupture-of-membranes-before-23-weeks-gestation-and-factors-associated-with-its-success
#19
Ji-Hee Sung, Jin-Yi Kuk, Hyun-Hwa Cha, Suk-Joo Choi, Soo-Young Oh, Cheong-Rae Roh, Jong-Hwa Kim
OBJECTIVE: The purpose of this study is to investigate the factors associated with successful amniopatch treatment in patients with iatrogenic preterm premature rupture of membranes (iPPROM) or spontaneous PPROM (sPPROM) before 23 weeks' gestation. MATERIALS AND METHODS: This cohort study included 28 women who received amniopatch treatment due to iPPROM or sPPROM at 15-23 weeks' gestation. Patients' clinical characteristics before performing the amniopatch, factors associated with the procedure, pregnancy and neonatal outcomes were compared between the iPPROM and sPPROM groups, and also between the successful and failed groups...
October 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29020221/systemic-inflammatory-response-to-malaria-during-pregnancy-is-associated-with-pregnancy-loss-and-preterm-delivery
#20
Michal Fried, Jonathan D Kurtis, Bruce Swihart, Sunthorn Pond-Tor, Amadou Barry, Youssoufa Sidibe, Santara Gaoussou, Moussa Traore, Sekouba Keita, Almahamoudou Mahamar, Oumar Attaher, Adama B Dembele, Kadidia B Cisse, Bacary S Diarra, Moussa B Kanoute, Alassane Dicko, Patrick E Duffy
Background: Pregnancy malaria (PM) is associated with a proinflammatory immune response characterized by increased levels of cytokines and chemokines such as tumor necrosis factor-α, interferon-γ, interleukin 10 (IL-10), and CXCL9. These changes are associated with poor outcomes including low birthweight delivery and maternal anemia. However, it is unknown if inflammatory pathways during malaria are related to pregnancy loss and preterm delivery (PTD). Methods: Cytokine and chemokine levels were measured in maternal peripheral blood at enrollment, gestational week 30-32, and delivery, and in placental blood, of 638 women during a longitudinal cohort study in Ouelessebougou, Mali...
July 20, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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