keyword
MENU ▼
Read by QxMD icon Read
search

Lichen planus

keyword
https://www.readbyqxmd.com/read/29146053/usefulness-of-a-direct-immunofluorescence-in-the-diagnosis-of-plaque-type-oral-lichen-planus
#1
Patricia Alejandra Masquijo-Bisio, Mariana Silvia Gandolfo, Alicia Keszler, Maria Elina Itoiz, María Luisa Paparella
No abstract text is available yet for this article.
December 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29144206/c-jun-expression-in-lichen-planus-psoriasis-and-cutaneous-squamous-cell-carcinoma-an-immunohistochemical-study
#2
Asmaa Gaber Abdou, Alaa Hassan Marae, Mohammed Shoeib, Ghada Dawood, Enas Abouelfath
The AP-1 transcription factor complex is a key player in regulating inflammatory processes, cell proliferation, differentiation and cell transformation. The aim of the present study is to investigate C-Jun (one of AP-1complex) expression and its proliferative role in skin samples of lichen planus, psoriasis as common inflammatory skin diseases and squamous cell carcinoma using immunohistochemical method. The present study was carried out on skin biopsies of 15 psoriatic patients, 15 lichen planus patients, 15 SCC and 15 normal skin biopsies...
November 16, 2017: Journal of Immunoassay & Immunochemistry
https://www.readbyqxmd.com/read/29141063/novel-treatment-using-low-dose-naltrexone-for-lichen-planopilaris
#3
Lauren C Strazzulla, Lorena Avila, Kristen Lo Sicco, Jerry Shapiro
<p>Lichen planopilaris (LPP) is a variant of lichen planus that affects the scalp causing scarring hair loss. Patients also frequently experience symptoms of scalp itch, pain, and burning. To date, there are no long-term remittive nor curative therapies available. Low-dose naltrexone has anti-inflammatory properties and has recently been described in the context of treating autoimmune conditions. This retrospective medical record review describes four LPP patients treated with low-dose (3 milligrams per day) naltrexone...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29139359/oral-lichen-planus-a-cross-sectional-descriptive-study-of-33-patients
#4
Virendra N Sehgal, Nazim Hussain Syed, Ashok Aggarwal, Shruti Sehgal
Oral lichen planus (OLP), a well-known entity, is often neglected; however, its assessment is considered essential for evolving future strategies for treatment. Thirty-three patients with OLP from 200 consecutive patients with oral mucosal lesions were studied according to demography. Tobacco chewing, smoking, and alcohol intake were recorded. Examination of the oral cavity, using a head light and tongue depressor, was undertaken to define the morphology of the lesion(s). Colored photographs were an essential part of the process...
2017: Skinmed
https://www.readbyqxmd.com/read/29139037/prevalence-of-oral-lichen-planus-in-iranian-children-and-adolescents-a-12-year-retrospective-study
#5
S Bakhtiari, J B Taheri, P Toossi, S Azimi, Sh Kawosi Nezhad
AIM: To investigate the prevalence of oral lichen planus in patients younger than 18 years, referred to a dermatology centre in Iran during 2002-2014. Lichen planus is a chronic inflammatory, immune-mediated disease that could affect the oral mucosa and is a pre-cancerous condition. The disease usually develops in middle age with female predominance and is rare in children. METHODS: In this retrospective study, cases with definitive histopathologic diagnosis of lichen planus, over a 12-year period from 2002 to 2014 from a dermatologic hospital archive were evaluated...
November 14, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29138813/reduced-mirna%C3%A2-214-expression-in-oral-mucosa-contributes-to-the-pathogenesis-of-oral-lichen-planus-by-targeting-cd44
#6
Haiyan Zheng, Shaohui Li
The present study aimed to investigate the role of miRNAs during the pathogenesis of oral lichen planus (OLP). OLP is a chronic inflammatory disorder, which involves T‑cell mediated autoimmunity and affects the skin, scalp, nails and mucosa. Abundant T lymphocytes have been demonstrated to infiltrate the oral mucosa, in which the activated T cells trigger apoptosis of oral epithelial cells. Overexpression of osteopontin (OPN) and CD44 has been observed in the mucosa of patients with OLP, and it has been confirmed that OPN suppresses the apoptosis of activated CD8+ T cells via CD44...
November 10, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29135114/expression-and-role-of-p53-in-oral-lichen-planus-patients
#7
Milos Hadzi-Mihailovic, Renata Petrovic, Helene Raybaud, Dragan Stanimirovic, Meltem Ozar Koray
PURPOSE: Oral lichen planus (OLP) is an autoimmune skin and mucosal disorder. The range of malignant transformation in OLP varies between 0.1-3%. p53 is a tumor suppressor protein. Defective p53 could allow abnormal cells to proliferate, resulting in cancer. p53 plays an important role in cell cycle control and apoptosis and loss of p53 function has been demonstrated in about half of all human cancers. The purpose of the study was to investigate the malignant potential of OLP on the basis of p53 expression and to correlate p53 expression with clinical and histopathological features of OLP...
September 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29130773/alteration-of-salivary-glycopatterns-in-oral-lichen-planus
#8
Liang Fang, Qing Liu, Pengfei He, Xinwen Wang, Ying Wang, Minghui Wei, Lihua Chen
BACKGROUND: Oral lichen planus (OLP) is one of the most common oral mucosal lesions affecting 0.5% to 2% of the adult population. It is difficult to distinguish between OLP and other oral mucosal diseases. Structural changes in the glycans of saliva proteins might be reliable indicators of OLP. However, little is known about the alteration of salivary glycopatterns during OLP. OBJECTIVE: We aimed to investigate the alterations of salivary protein glycosylation related to OLP...
November 13, 2017: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29124831/a-prospective-observational-study-to-compare-efficacy-of-topical-triamcinolone-acetonide-0-1-oral-paste-oral-methotrexate-and-a-combination-of-topical-triamcinolone-acetonide-0-1-and-oral-methotrexate-in-moderate-to-severe-oral-lichen-planus
#9
P Chauhan, D De, S Handa, T Narang, U N Saikia
Topical corticosteroids are considered to be the most effective treatment for oral lichen planus (OLP). Methotrexate has been found to be effective in extensive cutaneous lichen planus. The objectives of the study were to evaluate the clinical efficacy and safety of topical triamcinolone 0.1% oral paste, oral methotrexate and a combination of these in symptomatic moderate-to- severe OLP. Forty-five patients were recruited and were allocated to three treatment arms with 15 patients in each treatment arm. They were treated for a period of 16 weeks or until complete clinical remission, whichever was earlier...
November 10, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/29123636/management-of-oral-lichen-planus-by-980-nm-diode-laser
#10
Nahid Derikvand, Seyedeh Sara Ghasemi, Mohammad Moharami, Ehsan Shafiei, Nasim Chiniforush
Introduction: Oral lichen planus (OLP) is a mucocutaneous disease with uncertain etiology. As the etiology is unknown standard treatment modalities are not available. The traditional and common treatment relies on corticosteroids whether topical or systemic. In recent years, development of lasers made a proper path to use this instrument for treatment of the diseases which are refractory to conventional treatments. Previous studies in this field used CO2, ND:YAG, Excimer and some wavelength of diode lasers for the treatment of different types of lichen planus...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29121431/outcomes-of-oral-lichen-planus-and-oral-lichenoid-lesions-treated-with-topical-corticosteroid
#11
M A Gonzalez-Moles, J A Gil-Montoya, L Gonzalez-Ruiz, P Ramos, M Bravo
OBJECTIVE: To determine corticosteroid treatment effectiveness in patients with Oral Lichen Planus/Oral Lichenoid Lesions (OLP/OLL). MATERIAL AND METHODS: Twenty-one OLP and eighty-one OLL patients received 0.05% clobetasol propionate (CP) or 0.05% triamcinolone acetonide (TA) in aqueous solution (AS) or orabase (OB), evaluating responses to treatment and follow-up compliance. RESULTS: Lesions were atrophic (72/102; 70.6%), extensive (58/100; 58%), producing eating difficulties (62/102; 60...
November 9, 2017: Oral Diseases
https://www.readbyqxmd.com/read/29118700/looking-beyond-the-cyclosporine-swish-and-spit-technique-in-a-recalcitrant-case-of-erosive-lichen-planus-involving-the-tongue
#12
Aastha Gupta, Kabir Sardana, Ram Kishan Gautam
Oral lichen planus is a relatively common autoimmune disease affecting the middle-aged population. Although no treatment is necessary for a benign asymptomatic case, in case of erosive lichen planus, topical corticosteroids form the mainstay of treatment. In case of failure, apart from tacrolimus, cyclosporine, using the "swish and spit" technique, is a valid therapeutic intervention. In our case, though, this therapeutic option had to be replaced by the systemic use of cyclosporine with gratifying results.
September 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/29109874/esophageal-lichen-planus-understanding-a-potentially-severe-stricturing-disease
#13
Bharat Rao, Abhishek Gulati, Blair Jobe, Shyam Thakkar
A 67-year-old woman with a long-standing history of recurrent dysphagia and esophageal strictures failed to respond to aggressive antireflux management. She required multiple dilations for symptomatic strictures that were discovered throughout the esophagus. Intralesional, topical, and systemic glucocorticoid therapies were utilized without resolution in symptoms. Several years after initial presentation, histopathology ultimately demonstrated lichenoid features and a diagnosis of esophageal lichen planus (ELP) was confirmed...
2017: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29104603/oral-lichen-planus-in-a-pediatric-patient-a-novel-therapeutic-approach
#14
Gaurav Sharma, Divesh Sardana, Puneeta Vohra, Shweta Rehani, Archna Nagpal
Lichen planus is a mucocutaneous disease, predominantly affecting the middle-aged individuals and may be associated with a plethora of signs and symptoms related to the skin, scalp, nails and mucous membranes. The definitive etiology of lichen planus is not yet known and no therapeutic modality has yet been universally accepted. Lichen planus in pediatric patients is a rare phenomenon and its presence in the oral mucosa is even rarer. The aim of this article is to present a rare case of a symptomatic oral lichen planus (OLP) occurring in a 12-year old child that was managed successfully with a novel sequential modality of topical retinoids followed by aloe vera gel application...
March 2017: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/29101247/evidence-of-earlier-thyroid-dysfunction-in-newly-diagnosed-oral-lichen-planus-patients-a-hint-for-endocrinologists
#15
Paolo G Arduino, Dora Karimi, Federico Tirone, Veronica Sciannameo, Fulvio Ricceri, Marco Cabras, Alessio Gambino, Davide Conrotto, Stefano Salzano, Mario Carbone, Roberto Broccoletti
The association between oral lichen planus (OLP) and hypothyroidism has been debated with conflicting results: some authors detected a statistically significant association between these two, while others did not confirm it. The aim of this study was to evaluate the thyroid status in patients with newly diagnosed OLP to test the null hypothesis that thyroid disease is not associated with an increased incidence of oral lesions, with a prospective case-control approach. A total of 549 patients have been evaluated, of whom 355 were female...
November 2017: Endocrine Connections
https://www.readbyqxmd.com/read/29076159/lichen-planus-pigmentosus-and-its-variants-review-and-update
#16
REVIEW
Juan Carlos Robles-Méndez, Paulina Rizo-Frías, Maira Elizabeth Herz-Ruelas, Amit G Pandya, Jorge Ocampo Candiani
Lichen planus pigmentosus (LPP) is considered a rare variant of lichen planus (LP). It is characterized by acquired dark brown to gray macular pigmentation located on sun-exposed areas of the face, neck, and flexures, commonly found in dark-skinned patients. In patients with LPP, an inflammatory lichenoid response results in marked pigmentary incontinence. It has been associated with hepatitis C virus, sun exposure, and contactants such as mustard oil and nickel. LPP-inversus affects fair and dark skin, predominantly involving flexural and intertriginous areas, while sun-exposed areas are spared; friction is an associated trigger...
October 26, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29057516/porphyromonas-gingivalis-lipopolysaccharide-induces-over-production-of-cc-chemokine-ligand-2-via-toll-like-receptor-4-in-oral-lichen-planus
#17
Qi Zeng, Xi Yang, Xiaobing Chen, Juan Xia, Bin Cheng, Xiaoan Tao
BACKGROUND: We recently reported that the CC chemokine ligand 2 (CCL2)-CC receptor 2 (CCR2) axis was involved in the pathogenesis of oral lichen planus (OLP). However, the exact mechanism for the high expression of CCL2 in OLP specimens is not clear. Therefore, this study was designed to investigate the potential role of the toll-like receptor 4 (TLR-4) pathway in overproduction of CCL2 in OLP lesions. METHODS: Immunohistochemical staining and real-time RT-PCR were used to detect TLR-4, CCL2, and CCR2 expression in OLP lesions...
October 23, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29053652/a-report-on-the-clinical-pathological-correlations-of-788-gingival-lesion
#18
A Gambino, M Carbone, R Broccoletti, P Carcieri, D Conrotto, M Carrozzo, P-G Arduino
BACKGROUND: The diagnosis and treatment of a variety of non-plaque related gingival diseases have become an integrated aspect of everyday dentistry. The aim of this study was to analyse the relationship between clinical appearance and histopathological features of gingival lesions in a large Northern Italian population. MATERIAL AND METHODS: A retrospective study of 788 cases of gingival and alveolar mucosal biopsies was set up. Statistical analysis was performed by calculating the odds ratio and 95% confidence interval (C...
November 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29044604/epstein-barr-virus-positive-mucocutaneous-ulcer-in-a-background-of-crohn-s-disease-and-waldenstr%C3%A3-m-macroglobulinemia-a-case-report-highlighting-diagnostic-pitfalls
#19
Larissa Sena Teixeira Mendes, James McCaul, Andrew Wotherspoon, Ayoma D Attygalle
A specialist haematopathology opinion was sought on a left palatine tonsillar excision biopsy performed for suspected carcinoma. The patient, a 72-year old male, presented with oropharyngeal dysphagia in May 2015 and was diagnosed with hypertrophic, ulcerated lichen planus on an incision biopsy of a white patch on the posterior third of the tongue. Topical steroids were commenced with clinical improvement. This article is protected by copyright. All rights reserved.
October 16, 2017: Histopathology
https://www.readbyqxmd.com/read/29035285/dermoscopy-and-patch-testing-in-patients-with-lichen-planus-pigmentosus-on-face-a-cross-sectional-observational-study-in-fifty-indian-patients
#20
Vinod Kumar Sharma, Vishal Gupta, Piyush Pahadiya, Kamal Kumar Vedi, Sudheer Arava, M Ramam
BACKGROUND: Lichen planus pigmentosus (LPP) is a common cause of facial melanosis in the dark-skinned population. At present, information on dermoscopy and patch testing in LPP is limited. OBJECTIVES: To describe dermoscopic findings and study the role of patch testing in patients with LPP on the face. METHODS: Facial lesions of 50 patients with LPP were studied dermoscopically, followed by histological evaluation. Patch and photopatch tests with the Indian Standard Series and Scandinavian series, respectively, and patient's own cosmetics were performed on all patients...
November 2017: Indian Journal of Dermatology, Venereology and Leprology
keyword
keyword
9061
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"