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https://www.readbyqxmd.com/read/28550762/forensic-age-estimation-by-morphometric-analysis-of-the-manubrium-from-3d-mr-images
#1
Naira P Martínez Vera, Johannes Höller, Thomas Widek, Bernhard Neumayer, Thomas Ehammer, Martin Urschler
Forensic age estimation research based on skeletal structures focuses on patterns of growth and development using different bones. In this work, our aim was to study growth-related evolution of the manubrium in living adolescents and young adults using magnetic resonance imaging (MRI), which is an image acquisition modality that does not involve ionizing radiation. In a first step, individual manubrium and subject features were correlated with age, which confirmed a statistically significant change of manubrium volume (Mvol:p<0...
May 12, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28550288/infants-learn-better-from-left-to-right-a-directional-bias-in-infants-sequence-learning
#2
Hermann Bulf, Maria Dolores de Hevia, Valeria Gariboldi, Viola Macchi Cassia
A wealth of studies show that human adults map ordered information onto a directional spatial continuum. We asked whether mapping ordinal information into a directional space constitutes an early predisposition, already functional prior to the acquisition of symbolic knowledge and language. While it is known that preverbal infants represent numerical order along a left-to-right spatial continuum, no studies have investigated yet whether infants, like adults, organize any kind of ordinal information onto a directional space...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28549883/a-non-iterative-multi-scale-approach-for-intensity-inhomogeneity-correction-in-mri
#3
Maryjo M George, S Kalaivani, M S Sudhakar
Intensity inhomogeneity is the prime obstacle for MR image processing like automatic segmentation, registration etc. This complication has strong dependence on the associated acquisition hardware and patient anatomy which recommends retrospective correction. In this paper, a new method is developed for correcting the intensity inhomogeneity using a non-iterative multi-scale approach that doesn't necessitate segmentation and any prior knowledge on the scanner or subject. The proposed algorithm extracts bias field at different scales using a Log-Gabor filter bank followed by smoothing operation...
May 23, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28549655/experimental-winter-warming-modifies-thermal-performance-and-primes-acorn-ants-for-warm-weather
#4
Heidi J MacLean, Clint A Penick, Robert R Dunn, Sarah E Diamond
The frequency of warm winter days is increasing under global climate change, but how organisms respond to warmer winters is not well understood. Most studies focus on growing season responses to warming. Locomotor performance is often highly sensitive to temperature, and can determine fitness outcomes through a variety of mechanisms including resource acquisition and predator escape. As a consequence, locomotor performance, and its impacts on fitness, may be strongly affected by winter warming in winter-active species...
May 23, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28549591/single-allele-lmbrd1-knockout-results-in-cardiac-hypertrophy
#5
Linda Tzu-Ling Tseng, Chieh-Liang Lin, Kuei-Hsiang Pan, Kai-Yuan Tzen, Ming-Jai Su, Chia-Ti Tsai, Yi-Han Li, Pai-Chi Li, Fu-Tien Chiang, Shin C Chang, Ming-Fu Chang
BACKGROUND/PURPOSE: LMBD1 protein, a type IV-B plasma membrane protein possessing nine putative trans-membrane domains, was previously demonstrated at cellular level to play a critical part in the signaling cascade of insulin receptor through its involvement in regulating clathrin-mediated endocytosis. However, at physiological level, the significance of LMBD1 protein in cardiac development remains unclear. METHODS: To understand the role of Lmbrd1 gene involved in the cardiac function, heterozygous knockout mice were used as an animal model system...
May 23, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28549426/effect-of-iptp-on-plasmodium-falciparum-antibody-levels-among-pregnant-women-and-their-babies-in-a-sub-urban-coastal-area-in-ghana
#6
Judith K Stephens, Eric Kyei-Baafour, Emmanuel K Dickson, Jones K Ofori, Michael F Ofori, Mark L Wilson, Isabella A Quakyi, Bartholomew D Akanmori
BACKGROUND: Women exposed to Plasmodium infection develop antibodies and become semi-immune. This immunity is suppressed during pregnancy making both the pregnant woman and the foetus vulnerable to the adverse effects of malaria, particularly by Plasmodium falciparum. Intermittent preventive treatment of malaria in pregnancy (IPTp) with Sulfadoxine-pyrimethamine (SP) tablets is one of the current interventions to mitigate the effects of malaria on both the pregnant woman and the unborn child...
May 26, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28549338/fast-backprojection-based-reconstruction-of-spectral-spatial-epr-images-from-projections-with-the-constant-sweep-of-a-magnetic-field
#7
Denis A Komarov, Hiroshi Hirata
In this paper, we introduce a procedure for the reconstruction of spectral-spatial EPR images using projections acquired with the constant sweep of a magnetic field. The application of a constant field-sweep and a predetermined data sampling rate simplifies the requirements for EPR imaging instrumentation and facilitates the backprojection-based reconstruction of spectral-spatial images. The proposed approach was applied to the reconstruction of a four-dimensional numerical phantom and to actual spectral-spatial EPR measurements...
May 17, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28549335/microstructural-alterations-of-white-matter-in-juvenile-myoclonic-epilepsy
#8
Jinnan Gong, Xuebin Chang, Sisi Jiang, Benjamin Klugah-Brown, Song Tan, Dezhong Yao, Cheng Luo
Juvenile myoclonic epilepsy (JME) is a common type of idiopathic generalized epilepsy that is characterized by myoclonic jerks of the upper limbs and generalized tonic-clonic seizures. Frontal cognitive dysfunctions and abnormal coupling of the thalamocortical system have been found in neuropsychological and neuroimaging studies. This study intended to explore white matter (WM) measurement changes in JME using MRI. Twenty-six patients with JME and 25 healthy controls (HC) were recruited for the acquisition of diffusion MRI and structural MRI data...
April 4, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28549221/preventing-underfeeding-and-overfeeding-a-clinician-s-guide-to-the-acquisition-and-implementation-of-indirect-calorimetry
#9
Amy K Ladd, Heather E Skillman, Matthew A Haemer, Peter M Mourani
BACKGROUND: In critically ill patients, indirect calorimetry (IC) is the gold standard to determine energy needs, as the use of predictive equations can result in underfeeding or overfeeding. The aim of this quality improvement (QI) initiative was to describe the rationale for and implementation of a process to target energy provision according to IC measurements in a tertiary academic medical center pediatric intensive care unit (PICU). MATERIALS AND METHODS: To justify the purchase of an indirect calorimeter for clinical use, a needs assessment was conducted, followed by a training and implementation period...
May 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28549141/risk-factors-for-acquisition-of-ctx-m-genes-in-pilgrims-during-hajj-2013-and-2014
#10
Thongpan Leangapichart, Hervé Tissot-Dupont, Didier Raoult, Ziad A Memish, Jean-Marc Rolain, Philippe Gautret
Background: Mass gatherings, especially the Hajj pilgrimage, provide favourable conditions for bacterial transmission among participants, which might contribute to the international spread of ESBL-producing Enterobacteriaceae (ESBL-E). Objectives: We conducted an analysis aimed at investigating risk factors for CTX-M gene ( bla CTX-M ) rectal carriage in 2013 and 2014 Hajj pilgrims. Methods: A total of 218 pilgrims provided paired pre- and post-Hajj rectal samples (2013, 129 pilgrims; 2014, 89 pilgrims)...
May 26, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28549023/technical-feasibility-of-a-combined-noncontrast-magnetic-resonance-protocol-for-preoperative-transcatheter-aortic-valve-replacement-evaluation
#11
Paola M Cannaò, Giuseppe Muscogiuri, U Joseph Schoepf, Carlo N De Cecco, Pal Suranyi, Virginia W Lesslie, Davide Piccini, Shivraman Giri, Akos Varga-Szemes
PURPOSE: The aim of this study was to prospectively evaluate the technical feasibility of a noncontrast magnetic resonance angiography (MRA) protocol using investigational prototype self-navigated 3D (SN3D) radial whole-heart and quiescent-interval single-shot (QISS) pulse sequences regarding their potential in planning transcatheter aortic valve replacement (TAVR). MATERIALS AND METHODS: Five patients (76±7 y) with severe aortic valve stenosis and prior computed tomographic angiography (CTA) for TAVR planning and 10 healthy volunteers (28±6 y) underwent noncontrast MRA on a 1...
May 25, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28548990/outbreaks-of-nontuberculous-mycobacteria
#12
Geeta Sood, Nikki Parrish
PURPOSE OF REVIEW: The purpose of this review is to summarize the emerging literature on nontuberculous mycobacteria outbreaks in healthcare settings. As our ability to identify mycobacterial species develops, we are better able to recognize epidemiologic connections and better understand the prevalence and importance of these outbreaks and pseudo-outbreaks in healthcare settings. RECENT FINDINGS: The number of outbreaks related to nontuberculous outbreaks is increasing because of heightened awareness and better diagnostic tests for species level identification of mycobacteria...
May 25, 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/28548668/unique-capabilities-of-ac-frequency-scanning-and-its-implementation-on-a-mars-organic-molecule-analyzer-linear-ion-trap
#13
Dalton T Snyder, Desmond A Kaplan, Ryan M Danell, Friso H W van Amerom, Veronica T Pinnick, William B Brinckerhoff, Paul R Mahaffy, R Graham Cooks
A limitation of conventional quadrupole ion trap scan modes which use rf amplitude control for mass scanning is that, in order to detect a subset of an ion population, the rest of the ion population must also be interrogated. That is, ions cannot be detected out of order; they must be detected in order of either increasing or decreasing mass-to-charge (m/z). However, an ion trap operated in the ac frequency scan mode, where the rf amplitude is kept constant and instead the ac frequency is used for mass-selective operations, has no such limitation because any variation in the ac frequency affects only the subset of ions whose secular frequencies match the perturbation frequency...
May 26, 2017: Analyst
https://www.readbyqxmd.com/read/28548657/the-endobacterium-of-an-arbuscular-mycorrhizal-fungus-modulates-the-expression-of-its-toxin-antitoxin-systems-during-the-life-cycle-of-its-host
#14
Alessandra Salvioli di Fossalunga, Justine Lipuma, Francesco Venice, Laurence Dupont, Paola Bonfante
Arbuscular mycorrhizal fungi (AMF) are widespread root symbionts that perform important ecological services, such as improving plant nutrient and water acquisition. Some AMF from the Gigasporaceae family host a population of endobacteria, Candidatus Glomeribacter gigasporarum (Cagg). The analysis of the Cagg genome identified six putative toxin-antitoxin modules (TAs), consisting of pairs of stable toxins and unstable antitoxins that affect diverse physiological functions. Sequence analysis suggested that these TA modules were acquired by horizontal transfer...
May 26, 2017: ISME Journal
https://www.readbyqxmd.com/read/28548550/felis-catus-papillomavirus-type-2-dna-loads-on-kittens-are-transient-and-do-not-reflect-their-susceptibility-to-infection
#15
Neroli A Thomson, David G Thomas, Karin Weidgraaf, John S Munday
Objectives Felis catus papillomavirus type 2 (FcaPV-2) commonly infects the skin of domestic cats, and mounting evidence suggests that the virus could be involved in a subset of feline skin cancers. The reason why some cats develop FcaPV-2-induced disease and others do not is currently unknown. However, it has been shown that kittens in different litters have markedly different FcaPV-2 DNA loads and the aim of this study was to determine whether these differences could be due to inherent differences in susceptibility to infection...
May 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28548315/aapm-medical-physics-practice-guideline-8-a-linear-accelerator-performance-tests
#16
Koren Smith, Peter Balter, John Duhon, Gerald A White, David L Vassy, Robin A Miller, Christopher F Serago, Lynne A Fairobent
PURPOSE: The purpose of this guideline is to provide a list of critical performance tests in order to assist the Qualified Medical Physicist (QMP) in establishing and maintaining a safe and effective quality assurance (QA) program. The performance tests on a linear accelerator (linac) should be selected to fit the clinical patterns of use of the accelerator and care should be given to perform tests which are relevant to detecting errors related to the specific use of the accelerator. METHODS: A risk assessment was performed on tests from current task group reports on linac QA to highlight those tests that are most effective at maintaining safety and quality for the patient...
May 26, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28548290/metacarpal-growth-during-adolescence-in-a-longitudinal-south-african-cohort
#17
A Magan, L H Nyati, L K Micklesfield, S A Norris, J M Pettifor
To monitor the drift of the periosteal and endocortical surfaces during metacarpal growth longitudinally, radiogrammetry was carried out on hand-wrist x-rays of 572 children from the Birth to Twenty Bone Health Cohort annually from ages 9-21 years. This is the largest collection of longitudinal x-rays in African children. The 2(nd) metacarpal bone length, bone width and medullary width were measured using digital vernier callipers on a total of 4730 x-rays. Superimposition by Translation and Rotation (SITAR) was used to obtain age at peak metacarpal length velocity (PLV)...
May 26, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28548044/falcon-a-highly-flexible-open-source-software-for-closed-loop-neuroscience
#18
Davide Ciliberti, Fabian Kloosterman
OBJECTIVE: Closed-loop experiments provide unique insights into brain dynamics and function. Here, we demonstrate an open-source software platform that enables high-performance real-time processing of streaming experimental data, suitable for a wide range of closed-loop experiments. APPROACH: We wrote a C++ multi-threaded software (Falcon) in which the user can load and execute an arbitrary processing graph. Each node in the graph is internally mapped to a single thread and nodes communicate with each other through thread-safe buffers...
May 26, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28547857/confocal-endomicroscopy-in-diagnosis-of-intestinal-chronic-graft-versus-host-disease
#19
Kathrin Rieger, Ute Günther, Ulrike Erben, Anja Kühl, Christoph Loddenkemper, Antonio Pezzutto, Britta Siegmund, Christian Bojarski
Graft-versus-host disease (GvHD) is a major complication of allogeneic stem cell transplantation. High-resolution in vivo histology of the intestine by confocal endomicroscopy (CEM) detects acute GvHD (aGvHD) with high sensitivity. This pilot study aims to evaluate the diagnostic value of CEM for intestinal chronic GvHD (cGvHD). The study included 20 patients with gastrointestinal symptoms and confirmed cGvHD in other organs as well as 20 patients with clinically suspected acute GvHD for control. Confocal endomicroscopy was performed as gastroscopy followed by sigmoidoscopy after intravenous injection of fluorescein (10%) and topical application of acriflavine (0...
May 25, 2017: Hematological Oncology
https://www.readbyqxmd.com/read/28547846/multiline-balanced-ssfp-for-rapid-functional-imaging-at-ultrahigh-field
#20
Philipp Ehses, Klaus Scheffler
PURPOSE: The goal of this study is to develop and evaluate a multiline balanced steady-state free-precession (bSSFP) sequence for passband functional MRI at ultrahigh field. METHODS: Passband bSSFP functional MRI experiments using a visual task were performed on a 9.4 T system with echo trains ranging from one up to seven echoes. We analyze the acquisition efficiency, temporal and thermal signal-to-noise ratio, as well as the observed blood oxygen-level-dependent (BOLD) signal changes...
May 25, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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