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Vitamine D MI

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https://www.readbyqxmd.com/read/28098047/vitamin-a-deficiency-suppresses-fish-immune-function-with-differences-in-different-intestinal-segments-the-role-of-transcriptional-factor-nf-%C3%AE%C2%BAb-and-p38-mitogen-activated-protein-kinase-signalling-pathways
#1
Li Zhang, Lin Feng, Wei-Dan Jiang, Yang Liu, Pei Wu, Sheng-Yao Kuang, Ling Tang, Wu-Neng Tang, Yong-An Zhang, Xiao-Qiu Zhou
The present study investigated the effects of dietary vitamin A on immune function in the proximal intestine (PI), mid intestine (MI) and distal intestine (DI) of young grass carp (Ctenopharyngodon idella). Fish were fed graded levels of dietary vitamin A for 10 weeks, and then a challenge test using an injection of Aeromonas hydrophila was conducted for 14 d. The results showed that, compared with the optimum vitamin A level, vitamin A deficiency significantly decreased fish growth performance, increased enteritis morbidity, decreased intestinal innate humoral immune response and aggravated intestinal inflammation...
January 18, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/27980361/the-relationship-between-vitamin-d-and-glaucoma-a-kangbuk-samsung-health-study
#2
Hyun Tae Kim, Joon Mo Kim, Jung Hoon Kim, Mi Yeon Lee, Yu Sam Won, Jae Yeun Lee, Ki Ho Park
PURPOSE: To investigate the relationship between vitamin D and glaucoma. METHODS: This retrospective, cross-sectional study included subjects who underwent a health screening at the Health Screening Center of Kangbuk Samsung Hospital from August 2012 to July 2013. All fundus photographs were reviewed by ophthalmologists. The ophthalmologists determined if an eye was glaucomatous based on the criteria set forth by the International Society of Geographical and Epidemiological Ophthalmology and by the appearance of the retinal nerve fiber layer and optic disc...
December 2016: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/27901035/homocysteine-reducing-b-vitamins-and-ischemic-heart-disease-a-separate-sample-mendelian-randomization-analysis
#3
J V Zhao, C M Schooling
BACKGROUND/OBJECTIVES: Observationally, homocysteine is positively associated with ischemic heart disease (IHD) and unhealthy lipids; folate and vitamin B12, which reduce homocysteine, are associated with lower IHD risk and healthy lipids. Randomized controlled trials have shown no benefits of folate and vitamin B12 for IHD. To clarify the role of these potential targets of intervention in IHD we assessed how genetically determined homocysteine, folate and vitamin-B12-affected IHD and lipids...
November 30, 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27777907/vitamin-d-deficiency-in-children-aged-6-to-12-years-single-center-s-experience-in-busan
#4
Young Eun Roh, Bo Ryung Kim, Won Bok Choi, Young Mi Kim, Min-Jung Cho, Hye-Young Kim, Kyung Hee Park, Kwang Hoon Kim, Peter Chun, Su Young Kim, Min Jung Kwak
PURPOSE: This study investigated the prevalence and risk factors associated with vitamin D deficiency in children. METHODS: We analyzed the medical records of 330 patients from the age of 6 to 12, who visited the endocrinology clinic of the Department of Pediatrics at Pusan National University Hospital, from September, 2013 to May, 2014. According to their serum 25-hydroxyvitamin D (25(OH)D) levels, the patients were grouped into either the deficiency group (25(OH)D<20 ng/mL), or the sufficiency group (25(OH)D≥20 ng/mL)...
September 2016: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/27746658/effect-of-vitamin-d-on-the-expression-of-inflammatory-biomarkers-in-cultured-sebocytes-treated-with-propionibacterium-acnes-or-ultraviolet-b-irradiation
#5
Weon Ju Lee, Min Ji Kim, Hyo Sub Ryu, Mi Yeung Sohn, Yong Hyun Jang, Seok-Jong Lee, Do Won Kim
No abstract text is available yet for this article.
October 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27688860/relationship-between-blood-mercury-concentration-and-bone-mineral-density-in-korean-men-in-the-2008-2010-korean-national-health-and-nutrition-examination-survey
#6
Yang Hee Kim, Jae Yong Shim, Min Seok Seo, Hyung Ji Yim, Mi Ra Cho
BACKGROUND: The results of previous studies on the association between blood mercury (Hg) and bone mineral density (BMD) are inconsistent. We therefore used a large-scale nationwide representative sample of Korean men to investigate the relationship between these two parameters. METHODS: A nationwide cross-sectional study was conducted using data from the 2008 to 2010 Korean National Health and Nutrition Examination Survey to evaluate the relationship between blood Hg and BMD and the prevalence of osteopenia or osteoporosis in 1,190 men over 50 years of age...
September 2016: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/27581957/serum-vitamin-d3-levels-are-not-associated-with-thyroid-cancer-prevalence-in-euthyroid-subjects-without-autoimmune-thyroid-disease
#7
Yun Mi Choi, Won Gu Kim, Tae Yong Kim, Sung Jin Bae, Hong-Kyu Kim, Eun Kyung Jang, Min Ji Jeon, Ji Min Han, Young Kee Shong, Won Bae Kim
BACKGROUND/AIMS: Previous studies have suggested that elevated serum vitamin D levels might protect against thyroid cancer. Elevated serum thyroid stimulating hormone levels and autoimmune thyroid disease (AITD) are suggested to be thyroid cancer promoting factors but have not been well controlled in previous studies. We designed the present study to evaluate whether serum vitamin D levels are associated with thyroid cancer in euthyroid patients with no clinical evidence of AITD. METHODS: This cross-sectional study included subjects who underwent routine health check-ups, including serum 25-hydroxy vitamin D3 (25(OH)D3) levels, anti-thyroid peroxidase antibody (TPO-Ab), and thyroid ultrasonography (US)...
January 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27558316/metabolic-pathways-of-lung-inflammation-revealed-by-high-resolution-metabolomics-hrm-of-h1n1-influenza-virus-infection-in-mice
#8
Joshua D Chandler, Xin Hu, Eun-Ju Ko, Soojin Park, Young-Tae Lee, Michael Orr, Jolyn Fernandes, Karan Uppal, Sang-Moo Kang, Dean P Jones, Young-Mi Go
Influenza is a significant health concern worldwide. Viral infection induces local and systemic activation of the immune system causing attendant changes in metabolism. High-resolution metabolomics (HRM) uses advanced mass spectrometry and computational methods to measure thousands of metabolites inclusive of most metabolic pathways. We used HRM to identify metabolic pathways and clusters of association related to inflammatory cytokines in lungs of mice with H1N1 influenza virus infection. Infected mice showed progressive weight loss, decreased lung function, and severe lung inflammation with elevated cytokines [interleukin (IL)-1β, IL-6, IL-10, tumor necrosis factor (TNF)-α, and interferon (IFN)-γ] and increased oxidative stress via cysteine oxidation...
November 1, 2016: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/27503176/the-association-of-vitamin-d-with-estimated-glomerular-filtration-rate-and-albuminuria-5th-korean-national-health-and-nutritional-examination-survey-2011-2012
#9
Jong Park, So-Yeon Ryu, Mi-Ah Han, Seong-Woo Choi
OBJECTIVES: The kidney plays a key role in the metabolism of vitamin D. However, the relationship between GFR and 25(OH)D is not well understood. Moreover, few studies have investigated the effect of albuminuria, a known mediator of kidney function, on vitamin D levels. Our aim was to investigate the associations among estimated GFR (eGFR), albumin-creatinine ratio (ACR), and 25(OH)D. METHODS: We investigated the relationship of 25-hydroxyvitamin D (25[OH]D) with eGFR and albuminuria in 11,336 adults who participated in the 5th Korea National Health and Nutrition Examination Survey (KNHANES) 2011-2012...
November 2016: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/27456065/vitamin-d-deficiency-promotes-liver-tumor-growth-in-transforming-growth-factor-%C3%AE-smad3-deficient-mice-through-wnt-and-toll-like-receptor-7-pathway-modulation
#10
Jian Chen, Lior H Katz, Nina M Muñoz, Shoujun Gu, Ji-Hyun Shin, Wilma S Jogunoori, Mi-Hye Lee, Mitchell D Belkin, Sang-Bae Kim, Jon C White, Jaclyn Andricovich, Alexandros Tzatsos, Shulin Li, Sang Soo Kim, Kirti Shetty, Bibhuti Mishra, Asif Rashid, Ju-Seog Lee, Lopa Mishra
Disruption of the TGF-β pathway is associated with liver fibrosis and suppression of liver tumorigenesis, conditions associated with low Vitamin D (VD) levels. However, potential contributions of VD to liver tumor progression in the context of TGF-β signaling remain unexplored. Our analyses of VD deprivation (VDD) in in vivo models of liver tumor formation revealed striking three-fold increases in tumor burden in Smad3(+/-) mice, with a three-fold increase in TLR7 expression compared to controls. ChIP and transcriptional assays confirm Smad3 binding at two TLR7 promoter SBE sites...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27444567/association-of-metabolic-syndrome-and-25-hydroxyvitamin%C3%A2-d-with-cognitive-impairment-among-elderly-koreans
#11
Eun Young Lee, Su Jin Lee, Kyoung Min Kim, Young Mi Yun, Bo Mi Song, Jong Eun Kim, Hyeon Chang Kim, Yumie Rhee, Yoosik Youm, Chang Oh Kim
AIM: Metabolic syndrome and vitamin D deficiency are prevalent in older adults, and are considered risk factors for cognitive impairment. We investigated the combined effects of MetS and serum 25-hydroxyvitamin D (25[OH]D) levels on cognitive function in older adults. METHODS: We studied 2940 participants aged ≥65 years from the Korean Urban Rural Elderly cohort study. Metabolic syndrome was defined according to the updated Adult Treatment Panel III criteria...
July 22, 2016: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/27423568/vitamin-d-levels-are-not-predictors-of-survival-in-a-clinic-population-of-patients-with-als
#12
Jiwon Yang, Jin-Seok Park, Ki-Wook Oh, Seong-Il Oh, Hyeon-Mi Park, Seung Hyun Kim
OBJECTIVE: This study aimed to measure serum 25-hydroxyvitamin D [25(OH)D] concentrations, bone mineral density (BMD), and the parameters of bone metabolism in amyotrophic lateral sclerosis (ALS) patients, and their correlation with survival. METHODS: We retrospectively analysed data of 100 ALS patients who consecutively visited a single referral ALS clinic between January and December 2011. Sex; age and site of symptom onset; and death were recorded. Serum 25(OH)D concentration was dichotomized as <10ng/ml and ≥10ng/ml...
August 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27401647/association-between-vitamin-d-deficiency-and-anemia-in-patients-with-end-stage-renal-disease-a-cross-sectional-study
#13
Yung Ly Kim, Hyunwook Kim, Young Eun Kwon, Dong Ryeol Ryu, Mi Jung Lee, Kyung Sook Park, Han Jak Ryu, Jung Tak Park, Hyung Jung Oh, Seung Hyeok Han, Tae Hyun Yoo, Shin Wook Kang
PURPOSE: Despite new treatment strategies, anemia remains the most prevalent complication in patients with end-stage renal disease (ESRD). We investigated whether 25-hydroxyvitamin D [25(OH)D3] deficiency was associated with anemia in ESRD patients. MATERIALS AND METHODS: We reviewed the medical records of 410 ESRD patients who had undergone renal transplantation (RTx) at Yonsei University Health System and who had 25(OH)D3 levels measured at the time of RTx. Patients were divided into two groups based on baseline 25(OH)D3 concentrations: group 1, 25(OH)D3 levels <10 ng/mL; and group 2, 25(OH)D3 levels ≥10 ng/mL...
September 2016: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27314328/the-effect-of-analogues-of-1%C3%AE-25-dihydroxyvitamin-d%C3%A2-on-the-regrowth-and-gene-expression-of-human-colon-cancer-cells-refractory-to-5-fluorouracil
#14
Jacek Neska, Paweł Swoboda, Małgorzata Przybyszewska, Agnieszka Kotlarz, Narasimha Rao Bolla, Joanna Miłoszewska, Monika Anna Grygorowicz, Andrzej Kutner, Sergiusz Markowicz
This study aimed to evaluate the capacity of hypocalcemic analogues of 1α,25-dihydroxyvitamin D₂ (1,25D2) and 1α,25-dihydroxyvitamin D₃ (1,25D3) to inhibit regrowth and regulate the stemness-related gene expression in colon cancer cells undergoing renewal after exposure to 5-fluorouracil (5-FU). All of the tested analogues of 1,25D2 equally potently decreased the clonogenicity and the proliferative activity of HT-29 cells which survived the exposure to 5-FU, but differently regulated gene expression of these cells during their renewal...
June 14, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27313664/autophagy-enhancement-contributes-to-the-synergistic-effect-of-vitamin-d-in-temozolomide-based-glioblastoma-chemotherapy
#15
Dong-Ho Bak, Seong Hee Kang, DU Ri Choi, Mi Na Gil, Kwang Sik Yu, Ji Heun Jeong, Nam-Seob Lee, Je-Hun Lee, Young-Gil Jeong, Dong Kwan Kim, DO-Kyung Kim, Jwa-Jin Kim, Seung-Yun Han
Temozolomide (TMZ), an alkylating agent, is recommended as the initial treatment for high-grade glioblastoma. TMZ is widely used, but its short half-life and the frequency of tumor resistance limit its therapeutic efficacy. In the present study, the anticancer effect of vitamin D (VD) combined with TMZ upon glioblastoma was determined, and the underlying mechanism of this effect was identified. Through cell viability, clonogenic and wound healing assays, the current study demonstrated that treatment of a C6 glioblastoma cell line with TMZ and VD resulted in significantly increased in vitro antitumor effects compared with either VD or TMZ alone...
June 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27179408/the-cross-sectional-relationships-of-dietary-and-serum-vitamin-d-with-cardiometabolic-risk-factors-metabolic-components-subclinical-atherosclerosis-and-arterial-stiffness
#16
Ji Yeon Kang, Mi Kyung Kim, Sukyoung Jung, Jinho Shin, Bo Youl Choi
OBJECTIVE: There has been increasing interest in non-skeletal interactions between vitamin D insufficiency, which is common, and cardiovascular event and cardiovascular disease (CVD) risk factors. METHODS: To evaluate cross-sectional associations between dietary and serum vitamin D status and metabolic abnormalities and arterial changes among 1054 adults aged ≥40 y (404 men and 650 women) in a rural area of South Korea. Study subjects were divided into three groups according to dietary vitamin D intake (tertiles) measured by food frequency questionnaire and serum 25(OH)D levels (≤20, 21-29, and ≥30 ng/mL)...
October 2016: Nutrition
https://www.readbyqxmd.com/read/27114415/relationship-between-25-hydroxyvitamin-d-levels-and-liver-fibrosis-as-assessed-by-transient-elastography-in-patients-with-chronic-liver-disease
#17
Bong Jin Ko, Young Seok Kim, Sang Gyune Kim, Jung Hwan Park, Sae Hwan Lee, Soung Won Jeong, Jae Young Jang, Hong Soo Kim, Boo Sung Kim, Sun Mi Kim, Young Don Kim, Gab Jin Cheon, Bo Ra Lee
BACKGROUND/AIMS: Deficiencies of 25-hydroxyvitamin D (25(OH)D) are prevalent in patients with chronic liver disease (CLD). Liver fibrosis is the main determinant of CLD prognosis. The present study was performed to evaluate the correlation between 25(OH)D levels and liver fibrosis as assessed by transient elastography (TE) in patients with compensated CLD. METHODS: Serum 25(OH)D levels and liver stiffness were determined in a total of 207 patients who were subjected to the following exclusion criteria: patients with decompensated CLD; patients who had malignancies; patients who were taking medications; and patients who were pregnant...
September 15, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27030280/relationship-between-high-serum-ferritin-level-and-glaucoma-in-a-south-korean-population-the-kangbuk-samsung-health-study
#18
Hyo Jung Gye, Joon Mo Kim, Chungkwon Yoo, Seong Hee Shim, Yu Sam Won, Ki Chul Sung, Mi Yeon Lee, Ki Ho Park
BACKGROUND/AIMS: To investigate the association between serum ferritin levels and glaucoma in a South Korean population. METHODS: This retrospective cross-sectional study included 164 029 subjects who underwent screening at Kangbuk Samsung Hospital Health Screening Center between August 2012 and July 2013. All subjects underwent a physical examination, answered sociodemographic and behavioural questions, and provided samples for laboratory analyses. A digital fundus photograph of both eyes was taken, and all photographs were reviewed by ophthalmologists...
December 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27022466/mirna-27b-levels-are-associated-with-cyp3a-activity-in%C3%A2-vitro-and-in%C3%A2-vivo
#19
Lena Ekström, Ilona Skilving, Marie-Louise Ovesjö, Eleni Aklillu, Hanna Nylén, Anders Rane, Ulf Diczfalusy, Linda Björkhem-Bergman
Previous in vitro studies have shown that microRNA-27b (miR-27b) may regulate mRNA levels of CYP3A4, vitamin D receptor (VDR), and Peroxisome proliferator-activated receptor α (PPAR α) as well as CYP3A4 protein expression and activity. In vitro studies have also shown that vitamin D may affect the expression of CYP3A4. The primary aim of this pilot study was to investigate the association between miR-27b and CYP3A expression and activity. The secondary aim was to investigate the association between 25-hydroxy vitamin D in serum and CYP3A activity...
December 2015: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/26923181/osseoinductive-elements-around-immediate-implants-for-better-osteointegration-a-pilot-study-in-foxhound-dogs
#20
O Salomó-Coll, J E Val de Maté-Sánchez, M P Ramírez-Fernandez, F Hernández-Alfaro, J Gargallo-Albiol, J L Calvo-Guirado
OBJECTIVE: The aim of this study was to evaluate the effects on osseointegration of topical applications of melatonin vs. vitamin D over surfaces of immediate implants. MATERIALS AND METHODS: Mandibular premolar distal roots (P2 , P3 , P4 ) were extracted bilaterally from six American Foxhound dogs. Three conical immediate implants were randomly placed bilaterally in each mandible. Three randomized groups were created: melatonin 5% test group (MI), vitamin D 10% test group (DI), and Control group implants (CI)...
February 29, 2016: Clinical Oral Implants Research
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