Jennifer L Steel, Charles J George, Lauren Terhorst, Jonathan G Yabes, Vincent Reyes, Dan P Zandberg, Marci Nilsen, Gauri Kiefer, Jonas Johnson, Christopher Marsh, Jason Bierenbaum, Nishant Tageja, Michal Krauze, Robert VanderWeele, Gaurav Goel, Gopala Ramineni, Michael Antoni, Yoram Vodovotz, Jon Walker, Samer Tohme, Timothy Billiar, David A Geller
BACKGROUND: The current standard of care of screening and referring patients for treatment for symptoms, such as depression, pain, and fatigue, is not effective. This trial aimed to test the efficacy of an integrated screening and novel stepped collaborative care intervention versus standard of care for patients with cancer and at least one of the following symptoms: depression, pain, or fatigue. METHODS: This randomised, parallel, phase 3 trial was conducted in 29 oncology outpatient clinics associated with the UPMC Hillman Cancer Center in the USA...
March 12, 2024: Lancet