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https://www.readbyqxmd.com/read/29651510/-vomiting-and-collapse-of-a-28-year-old-male-long-distance-runner-in-middle-european-summer
#1
J Herold, A Mitrasch, E Lorenz, U Lodes, I Tanev, R Braun-Dullaeus, F Meyer
BACKGROUND: Hyperthermia often ends fatally and must therefore be promptly recognized and adequately treated. CASE: A 28-year-old man participated in a long-distance race (3 km) on a hot summer day (28 °C). The runner collapsed, had to vomit but continued the run and reached the finish. Neurologically, the patient presented with intermittent cerebral seizures. External cooling batteries were immediately applied and cold infusions were started. The patient was admitted to the intensive care unit of the university hospital (body temperature 40...
April 12, 2018: Der Internist
https://www.readbyqxmd.com/read/29623412/staying-hot-to-fight-the-heat-high-body-temperatures-accompany-a-diurnal-endothermic-lifestyle-in-the-tropics
#2
Danielle L Levesque, Andrew Alek Tuen, Barry G Lovegrove
Much of our knowledge of the thermoregulation of endotherms has been obtained from species inhabiting cold and temperate climates, our knowledge of the thermoregulatory physiology of tropical endotherms is scarce. We studied the thermoregulatory physiology of a small, tropical mammal, the large treeshrew (Tupaia tana, Order Scandentia) by recording the body temperatures of free-ranging individuals, and by measuring the resting metabolic rates of wild individuals held temporarily in captivity. The amplitude of daily body temperature (~ 4 °C) was higher in treeshrews than in many homeothermic eutherian mammals; a consequence of high active-phase body temperatures (~ 40 °C), and relatively low rest-phase body temperatures (~ 36 °C)...
April 5, 2018: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/29616878/integrating-competing-demands-of-osmoregulatory-and-thermoregulatory-homeostasis
#3
Michael J McKinley, Davide Martelli, Glenn L Pennington, David Trevaks, Robin M McAllen
Mammals are characterized by a stable core body temperature. When maintenance of core temperature is challenged by ambient or internal heat loads, mammals increase blood flow to the skin, sweat and/or pant, or salivate. These thermoregulatory responses enable evaporative cooling at moist surfaces to dissipate body heat. If water losses incurred during evaporative cooling are not replaced, body fluid homeostasis is challenged. This article reviews the way mammals balance thermoregulation and osmoregulation.
May 1, 2018: Physiology
https://www.readbyqxmd.com/read/29599858/the-effects-of-cryotherapy-on-knee-joint-position-sense-and-force-production-sense-in-healthy-individuals
#4
Mariusz P Furmanek, Kajetan J Słomka, Andrzej Sobiesiak, Marian Rzepko, Grzegorz Juras
The proprioceptive information received from mechanoreceptors is potentially responsible for controlling the joint position and force differentiation. However, it is unknown whether cryotherapy influences this complex mechanism. Previously reported results are not universally conclusive and sometimes even contradictory. The main objective of this study was to investigate the impact of local cryotherapy on knee joint position sense (JPS) and force production sense (FPS). The study group consisted of 55 healthy participants (age: 21 ± 2 years, body height: 171...
March 2018: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29596491/core-and-skin-temperature-influences-on-the-surface-electromyographic-responses-to-an-isometric-force-and-position-task
#5
Nico A Coletta, Matthew M Mallette, David A Gabriel, Christopher J Tyler, Stephen S Cheung
The large body of work demonstrating hyperthermic impairment of neuromuscular function has utilized maximal isometric contractions, but extrapolating these findings to whole-body exercise and submaximal, dynamic contractions may be problematic. We isolated and compared core and skin temperature influences on an isometric force task versus a position task requiring dynamic maintenance of joint angle. Surface electromyography (sEMG) was measured on the flexor carpi radialis at 60% of baseline maximal voluntary contraction while either pushing against a rigid restraint (force task) or while maintaining a constant wrist angle and supporting an equivalent inertial load (position task)...
2018: PloS One
https://www.readbyqxmd.com/read/29595520/nickel-nanoparticles-stabilized-room-temperature-blue-phase-liquid-crystals
#6
Fashun Liu, Guanshui Ma, Dongyu Zhao
Blue phase liquid crystals (BPLCs) are regarded as the potential candidate for the next generation optical devices, but they appear in a
 narrow temperature range, which restricts their applicability. The nanoparticles stabilization of BPLCs which is usually about either simple-cubic blue phase (BPⅡ) or body-centered-cubic BP (BPⅠ). Hence, a nanoparticles-stabilized both BPⅡ and BPⅠ possessing wide
 temperature ranges has been scarcely reported. Here, nickel nanoparticles (Ni NPs) were synthesized and introduced into a BPLC...
March 29, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29593558/an-individualized-perception-based-protocol-to-investigate-human-physiological-responses-to-cooling
#7
Crystal L Coolbaugh, Emily C Bush, Elizabeth S Galenti, E Brian Welch, Theodore F Towse
Cold exposure, a known stimulant of the thermogenic effects of brown adipose tissue (BAT), is the most widely used method to study BAT physiology in adult humans. Recently, individualized cooling has been recommended to standardize the physiological cold stress applied across participants, but critical experimental details remain unclear. The purpose of this work was to develop a detailed methodology for an individualized, perception-based protocol to investigate human physiological responses to cooling. Participants were wrapped in two water-circulating blankets and fitted with skin temperature probes to estimate BAT activity and peripheral vasoconstriction...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29590555/activation-of-trpv1-in-nucleus-tractus-solitarius-reduces-brown-adipose-tissue-thermogenesis-arterial-pressure-and-heart-rate
#8
Mazher Mohammed, Christopher J Madden, Michael C Andresen, Shaun F Morrison
The sympathetic nerve activity (SNA) to brown adipose tissue (BAT) regulates BAT thermogenesis to defend body temperature in cold environments or to produce fever during immune responses. The vagus nerve contains afferents that inhibit the BAT SNA and BAT thermogenesis evoked by skin cooling. We sought to determine whether activation of TRPV1 channels in the nucleus tractus solitarius (NTS), which are prominently expressed in unmyelinated vagal afferents, would affect cold-evoked BAT thermogenesis, cardiovascular parameters, or their vagal afferent-evoked responses...
March 28, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29576991/cenozoic-aridization-in-central-eurasia-shaped-diversification-of-toad-headed-agamas-phrynocephalus-agamidae-reptilia
#9
Evgeniya N Solovyeva, Vladimir S Lebedev, Evgeniy A Dunayev, Roman A Nazarov, Anna A Bannikova, Jing Che, Robert W Murphy, Nikolay A Poyarkov
We hypothesize the phylogenetic relationships of the agamid genus Phrynocephalus to assess how past environmental changes shaped the evolutionary and biogeographic history of these lizards and especially the impact of paleogeography and climatic factors. Phrynocephalus is one of the most diverse and taxonomically confusing lizard genera. As a key element of Palearctic deserts, it serves as a promising model for studies of historical biogeography and formation of arid habitats in Eurasia. We used 51 samples representing 33 of 40 recognized species of Phrynocephalus covering all major areas of the genus...
2018: PeerJ
https://www.readbyqxmd.com/read/29557676/controlling-rectal-and-muscle-temperatures-can-we-offset-diurnal-variation-in-repeated-sprint-performance
#10
Samuel A Pullinger, Juha Oksa, Emma L Brocklehurst, Reece P Iveson, Antonia Newlove, Jatin G Burniston, Dominic A Doran, James M Waterhouse, Ben J Edwards
The present study investigated whether increasing morning rectal temperatures (Trec ) to resting.evening levels, or decreasing evening Trec or muscle (Tm ) temperatures to morning values, would influence repeated sprint (RS) performance in a causal manner. Twelve trained males underwent five sessions [age (mean ± SD) 21.8 ± 2.6 yr, peak oxygen uptake ([Formula: see text] peak) 60.6 ± 4.6 mL kg min-1 , stature 1.78 ± 0.07 m and body mass 76.0 ± 6.3 kg]. These included a control morning (M, 07:30 h) and evening (E, 17:30 h) session (5-min warm-up), and three further sessions consisting of a warm-up morning trial (ME , on a motorised treadmill) until Trec reached evening levels; and two cool-down evening trials (in 16-17°C water) until Trec (EMrec ) or Tm (EMmuscle ) values reached morning temperatures, respectively...
March 20, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29552392/methods-for-detecting-host-genetic-modifiers-of-tumor-vascular-function-using-dynamic-near-infrared-fluorescence-imaging
#11
Jaidip Jagtap, Gayatri Sharma, Abdul K Parchur, Venkateswara Gogineni, Carmen Bergom, Sarah White, Michael J Flister, Amit Joshi
Vascular supply is a critical component of the tumor microenvironment (TME) and is essential for tumor growth and metastasis, yet the endogenous genetic modifiers that impact vascular function in the TME are largely unknown. To identify the host TME modifiers of tumor vascular function, we combined a novel genetic mapping strategy [Consomic Xenograft Model] with near-infrared (NIR) fluorescence imaging and multiparametric analysis of pharmacokinetic modeling. To detect vascular flow, an intensified cooled camera based dynamic NIR imaging system with 785 nm laser diode based excitation was used to image the whole-body fluorescence emission of intravenously injected indocyanine green dye...
February 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29549995/in-shackleton-s-trails-central-and-local-thermoadaptive-modifications-to-cold-and-hypoxia-after-a-man-hauling-expedition-on-the-antarctic-plateau
#12
Michail E Keramidas, Roger Kölegård, Ola Eiken
Cold and hypoxia constitute the main environmental stressors encountered on the Antarctic Plateau. Hence, we examined whether central and/or peripheral acclimatisation to the combined stressors of cold and hypoxia would be developed in four men following an 11-day man-hauling expedition on this polar region. Before and after the journey, participants performed a static whole-body immersion in 21 °C water, during which they were breathing a hypoxic gas (partial pressure of inspired O2 : ~97 mmHg). To evaluate their local responses to cold, participants also immersed the hand into 8 °C water for 30 min, while they were whole-body immersed and mildly hypothermic [i...
April 2018: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29543239/cavity-enhanced-deep-ultraviolet-laser-for-two-photon-cooling-of-atomic-hydrogen
#13
S F Cooper, Z Burkley, A D Brandt, C Rasor, D C Yost
We demonstrate a 650 mW 243 nm continuous-wave laser coupled to a linear optical enhancement cavity. The enhancement cavity can maintain >30  W of intracavity power for 1 h of continuous operation without degradation. This system has sufficient power for a demonstration of two-photon laser cooling of hydrogen and may be useful for experiments on other simple two-body atomic systems.
March 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29541655/a-thermoreversible-photocrosslinkable-collagen-bio-ink-for-free-form-fabrication-of-scaffolds-for-regenerative-medicine
#14
Kathryn E Drzewiecki, Juilee N Malavade, Ijaz Ahmed, Christopher J Lowe, David I Shreiber
As a biomaterial, collagen has been used throughout tissue engineering and regenerative medicine. Collagen is native to the body, is highly biocompatible, and naturally promotes cell adhesion and regeneration. However, collagen fibers and the inherent weak mechanical properties of collagen hydrogels interfere with further development of collagen as a bio-ink. Herein, we demonstrate the use of a modified type-I collagen, collagen methacrylamide (CMA), as a fibril-forming bio-ink for free-form fabrication of scaffolds...
December 2017: Technology
https://www.readbyqxmd.com/read/29541134/effects-of-prolonged-running-in-the-heat-and-cool-environments-on-selected-physiological-parameters-and-salivary-lysozyme-responses
#15
Nur S Ibrahim, Chee K Chen, Ayunizma Ayub, Ayu S Muhamad
Introduction: Lysozyme is one of the salivary antimicrobial proteins which act as the "first line of defence" at the mucosal surface. The effects of prolonged exercise in the hot and cool environments among recreational athletes on salivary lysozyme responses are very limited in the literature, especially in the Asian countries. Objective: To determine the effects of prolonged running in the hot and cool environments on selected physiological parameters and salivary lysozyme responses among recreational athletes...
December 2017: Journal of Exercise Science and Fitness
https://www.readbyqxmd.com/read/29537944/the-effect-of-dynamic-friction-with-wet-fabrics-on-skin-wetness-perception
#16
Zhaohua Zhang, Xiangning Tang, Jun Li, Wenyi Yang
PURPOSE: To investigate the effect of cold stimulation (contacting wet fabric) and tactile stimulation (dynamic friction) on skin wetness perception: 1) wetness perception of fabric with different water transfer performance; 2) wetness perception of fabric with different water content; 3) wetness perception of fabric at different friction velocity with skin. METHODS: Twenty participants were screened as reliable assessors using a 7-point wetness rating scale. The dynamic friction between skin and fabric was simulated by a self-made device with adjustable speed controller...
March 14, 2018: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/29536587/lightweight-compact-and-high-performance-3t-mr-system-for-imaging-the-brain-and-extremities
#17
Thomas K F Foo, Evangelos Laskaris, Mark Vermilyea, Minfeng Xu, Paul Thompson, Gene Conte, Christopher Van Epps, Christopher Immer, Seung-Kyun Lee, Ek T Tan, Dominic Graziani, Jean-Baptise Mathieu, Christopher J Hardy, John F Schenck, Eric Fiveland, Wolfgang Stautner, Justin Ricci, Joseph Piel, Keith Park, Yihe Hua, Ye Bai, Alex Kagan, David Stanley, Paul T Weavers, Erin Gray, Yunhong Shu, Matthew A Frick, Norbert G Campeau, Joshua Trzasko, John Huston, Matt A Bernstein
PURPOSE: To build and evaluate a small-footprint, lightweight, high-performance 3T MRI scanner for advanced brain imaging with image quality that is equal to or better than conventional whole-body clinical 3T MRI scanners, while achieving substantial reductions in installation costs. METHODS: A conduction-cooled magnet was developed that uses less than 12 liters of liquid helium in a gas-charged sealed system, and standard NbTi wire, and weighs approximately 2000 kg...
March 13, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29534742/the-efficacy-and-safety-of-pre-hospital-cooling-after-out-of-hospital-cardiac-arrest-a-systematic-review-and-meta-analysis
#18
Patrick J Lindsay, Danielle Buell, Damon C Scales
BACKGROUND: Mild therapeutic hypothermia (TH), or targeted temperature management, improves survival and neurological outcomes in patients after out-of-hospital cardiac arrest (OHCA). International guidelines strongly support initiating TH for all eligible individuals presenting with OHCA; however, the timing of cooling initiation remains uncertain. This systematic review and meta-analysis was conducted with all available randomised controlled trials (RCTs) included to explore the efficacy and safety of initiating pre-hospital TH in patients with OHCA...
March 13, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29530988/deletion-of-the-cold-thermoreceptor-trpm8-increases-heat-loss-and-food-intake-leading-to-reduced-body-temperature-and-obesity-in-mice
#19
Alfonso Reimúndez, Carlos Fernández-Peña, Guillermo García, Rubén Fernández, Purificación Ordás, Rosalía Gallego, José L Pardo-Vazquez, Victor Arce, Félix Viana, Rosa Señarís
The coupling of energy homeostasis to thermoregulation is essential to maintain homeothermy in changing external environments. We studied the role of the cold thermoreceptor TRPM8 in this interplay in mice of both sexes. We demonstrate that TRPM8 is required for a precise thermoregulation in response to cold, in fed and fasting. Trpm8-/- mice exhibited a fall of 0.7 °C in core body temperature (Tc) when housed at cold temperatures, and a deep hypothermia (below 30 °C) during food deprivation. In both situations TRPM8-deficiency induced an increase in tail heat loss...
March 12, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29529383/physical-characteristics-cannot-be-used-to-predict-cooling-time-using-cold-water-immersion-as-a-treatment-for-exertional-hyperthermia
#20
Martin P Poirier, Sean R Notley, Andreas D Flouris, Glen P Kenny
We examined if physical characteristics could be used to predict cooling time during cold water immersion (CWI, 2°C) following exertional hyperthermia (rectal temperature ≥39.5°C) in a physically heterogeneous group of men and women (n=62). Lean body mass was the only significant predictor of cooling time following CWI (R<sup>2</sup>=0.137; P<0.001); however that prediction did not provide the precision (mean residual square error: 3.18±2.28 min) required to act as a safe alternative to rectal temperature measurements...
March 12, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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