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https://www.readbyqxmd.com/read/28926823/preparation-characterization-and-application-of-urease-nanoparticles-for-construction-of-an-improved-potentiometric-urea-biosensor
#1
Seema Jakhar, C S Pundir
The nanoparticles (NPs) aggregates of commercial urease from jack beans (Canavalia ensiformis) were prepared by desolvation and glutaraldehyde crosslinking and functionalized by cysteamine dihydrochloride. These enzyme nanoparticles (ENPs) were characterized by transmission electron microscopy (TEM), UV and Fourier transform infrared (FTIR) spectroscopy. The TEM images of urease NPs showed their size in the range, 18-100nm with an average of 51.2nm. The ENPs were more active and stable with a longer shelf life than native enzyme molecules...
September 6, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28926742/an-interpersonal-perspective-on-criterion-a-of-the-dsm-5-alternative-model-for-personality-disorders
#2
REVIEW
Aaron L Pincus
This paper links Criterion A of the Diagnostic and Statistical Manual of Mental Disorders-5th Edition Alternative Model for Personality Disorders with the contemporary interpersonal model of personality pathology. Advances in interpersonal theory and assessment are outlined to demonstrate that Criterion A's self (identity, self-direction) and interpersonal (empathy, intimacy) impairments are related to the interpersonal meta-constructs and agency and communion and are operationalized by perceptual, behavioral, and affective mechanisms of the interpersonal situation framework...
September 16, 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28925727/the-effect-of-person-order-on-egress-time-a-simulation-model-of-evacuation-from-a-neolithic-visitor-attraction
#3
Arthur Stewart, Eyad Elyan, John Isaacs, Leah McEwen, Lyn Wilson
OBJECTIVE: The aim of this study was to model the egress of visitors from a Neolithic visitor attraction. BACKGROUND: Tourism attracts increasing numbers of elderly and mobility-impaired visitors to our built-environment heritage sites. Some such sites have very limited and awkward access, were not designed for mass visitation, and may not be modifiable to facilitate disabled access. As a result, emergency evacuation planning must take cognizance of robust information, and in this study we aimed to establish the effect of visitor position on egress...
September 1, 2017: Human Factors
https://www.readbyqxmd.com/read/28925651/exercise-stress-testing-indications-and-common-questions
#4
Kathryn K Garner, William Pomeroy, James J Arnold
Exercise stress testing is a validated diagnostic test for coronary artery disease in symptomatic patients, and is used in the evaluation of patients with known cardiac disease. Testing of asymptomatic patients is generally not indicated. It may be performed in select deconditioned adults before starting a vigorous exercise program, but no studies have compared outcomes from preexercise testing vs. encouraging light exercise with gradual increases in exertion. Preoperative exercise stress testing is helpful for risk stratification in patients undergoing vascular surgery or who have active cardiac symptoms before undergoing nonemergent noncardiac surgery...
September 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28925419/mosaicqa-a-general-approach-to-facilitate-basic-data-quality-assurance-for-epidemiological-research
#5
Martin Bialke, Henriette Rau, Thea Schwaneberg, Rene Walk, Thomas Bahls, Wolfgang Hoffmann
BACKGROUND: Epidemiological studies are based on a considerable amount of personal, medical and socio-economic data. To answer research questions with reliable results, epidemiological research projects face the challenge of providing high quality data. Consequently, gathered data has to be reviewed continuously during the data collection period. OBJECTIVES: This article describes the development of the mosaicQA-library for non-statistical experts consisting of a set of reusable R functions to provide support for a basic data quality assurance for a wide range of application scenarios in epidemiological research...
May 29, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28925101/personal-use-of-hair-dyes-and-risk-of-leukemia-a-systematic-literature-review-and-meta-analysis
#6
REVIEW
Kevin M Towle, Matthew E Grespin, Andrew D Monnot
The objective of this study was to examine the association between personal use of hair dyes and the risk of leukemia. We conducted a systematic literature review of epidemiology studies reporting leukemia-specific cancer risks among hair dye users, and estimated the meta-relative risk (meta-RR) and corresponding 95% confidence interval (95% CI) of leukemia, comparing hair dye users to nonusers. When data from all 20 studies that met the inclusion criteria were combined, ever use of hair dye was associated with a nonstatistically significant increased risk of leukemia, meta-RR = 1...
September 18, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28924680/the-oncological-patient-in-the-palliative-situation
#7
Steffen Eychmueller, Diana Zwahlen, Monica Fliedner
Palliative care approaches patients and their suffering with a bio-psycho-social-spiritual model. Thus, it is the strength of palliative care to complement the diagnosis driven approach of medical cancer care by a problem and resources-based assessment, participatory care plan and person-directed interventions. Interventions need to reflect timely prognosis, target population (the patient, the family carer, the professional) and level of trust and remaining energy. In palliative care the relevance of psycho-oncological aspects in the care of the terminally ill is considerable in the understanding of the overall suffering of patients approaching death and their loved ones and in their care and support...
2018: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/28924502/factors-influencing-healthcare-provider-respondent-fatigue-answering-a-globally-administered-in-app-survey
#8
Vikas N O'Reilly-Shah
BACKGROUND: Respondent fatigue, also known as survey fatigue, is a common problem in the collection of survey data. Factors that are known to influence respondent fatigue include survey length, survey topic, question complexity, and open-ended question type. There is a great deal of interest in understanding the drivers of physician survey responsiveness due to the value of information received from these practitioners. With the recent explosion of mobile smartphone technology, it has been possible to obtain survey data from users of mobile applications (apps) on a question-by-question basis...
2017: PeerJ
https://www.readbyqxmd.com/read/28924472/the-effect-of-antibiotic-use-on-prevalence-of-nosocomial-vancomycin-resistant-enterococci-an-ecologic-study
#9
Cornelius Remschmidt, Michael Behnke, Axel Kola, Luis A Peña Diaz, Anna M Rohde, Petra Gastmeier, Frank Schwab
BACKGROUND: Vancomycin-resistant enterococci (VRE) are among the most common antimicrobial-resistant pathogens causing nosocomial infections. Although antibiotic use has been identified as a risk factor for VRE, it remains unclear which antimicrobial agents particularly facilitate VRE selection. Here, we assessed whether use of specific antimicrobial agents is independently associated with healthcare-associated (HA) VRE rates in a university hospital setting in Berlin, Germany. METHODS: We conducted the study between January 2014 and December 2015 at the Charité-university hospital of Berlin, Germany...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28923818/what-makes-for-successful-registry-implementation-a-qualitative-comparative-analysis
#10
Jodi Summers Holtrop, Tristen L Hall, Claude Rubinson, L Miriam Dickinson, Russell E Glasgow
PURPOSE: Registry implementation is an important component of successfully achieving patient-centered medical home designation and an important part of population-based health. The purpose of this study was to examine what factors are evident in the successful implementation of a registry in a selection of Colorado practices involved in quality-improvement activities. METHODS: In-depth, small-group interviews occurred at 13 practices. The data were recorded, transcribed, and qualitatively analyzed to identify key themes regarding elements of successful registry implementation...
September 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28923795/trends-in-standardized-mortality-among-individuals-with-schizophrenia-1993-2012-a-population-based-repeated-cross-sectional-study
#11
Evgenia Gatov, Laura Rosella, Maria Chiu, Paul A Kurdyak
BACKGROUND: We examined mortality time trends and premature mortality among individuals with and without schizophrenia over a 20-year period. METHODS: In this population-based, repeated cross-sectional study, we identified all individual deaths that occurred in Ontario between 1993 and 2012 in persons aged 15 and over. We plotted overall and cause-specific age- and sex-standardized mortality rates (ASMRs), stratified all-cause ASMR trends by sociodemographic characteristics, and analyzed premature mortality using years of potential life lost...
September 18, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28923521/why-do-people-with-mental-distress-have-poor-social-outcomes-four-lessons-from-the-capabilities-approach
#12
Richard Brunner
Macro level data indicate that people experiencing mental distress experience poor health, social and economic outcomes. The sociology of mental health has a series of dominant competing explanations of the mechanisms at personal, social and structural levels that generate these poor outcomes. This article explains the limitations of these approaches and takes up the challenge of Hopper (2007) who in this journal proposed the capabilities approach as a means of normatively reconceptualising the experiences of people with mental distress, with a renewed focus on agency, equality and genuine opportunity...
September 8, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28923106/impact-of-nursing-home-admission-on-health-care-use-and-disease-status-elderly-dependent-people-one-year-before-and-one-year-after-skilled-nursing-home-admission-based-on-2012-2013-sniiram-data
#13
A Atramont, I Bourdel-Marchasson, D Bonnet-Zamponi, I Tangre, A Fagot-Campagna, P Tuppin
BACKGROUND: The aim of this study was to compare disease status and health care use 1 year before and 1 year after skilled nursing home (SNH) admission. METHODS: People over the age of 65 years admitted to SNH during the first quarter of 2013, covered by the national health insurance general scheme (69% of the population of this age), and still alive 1 year after admission were identified (n = 14,487, mean age: 86 years, women: 76%). Their reimbursed health care was extracted from the Système National d'Information Interrégimes de l'Assurance Maladie (SNIIRAM) [National Health Insurance Information System]...
September 18, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28923007/patients-beliefs-regarding-informed-consent-for-low-risk-pragmatic-trials
#14
Rafael Dal-Ré, Antonio J Carcas, Xavier Carné, David Wendler
BACKGROUND: The requirement to obtain written informed consent may undermine the potential of pragmatic randomized clinical trials (pRCTs) to improve evidence-based care. This requirement could compromise trials statistical power or even force it to close them down prematurely. However, recent data from the U.S. and Spain suggest that a majority of the public endorses written consent for low-risk pRCTs. The present manuscript assesses whether this view is shared by patients. METHODS: This was a cross-sectional, probability-based survey, with a 2 × 2 factorial design, assessing support for written informed consent versus verbal consent or general notification for two low-risk pRCTs in hypertension, one comparing 2 drugs with similar risk/benefit profiles and the other comparing the same drug being taken in the morning or at night...
September 18, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28922903/banking-on-living-kidney-donors-a-new-way-to-facilitate-donation-without-compromising-on-ethical-values
#15
Dominique E Martin, Gabriel M Danovitch
Public surveys conducted in many countries report widespread willingness of individuals to donate a kidney while alive to a family member or close friend, yet thousands suffer and many die each year while waiting for a kidney transplant. Advocates of financial incentive programs or "regulated markets" in kidneys present the problem of the kidney shortage as one of insufficient public motivation to donate, arguing that incentives will increase the number of donors. Others believe the solutions lie-at least in part-in facilitating so-called "altruistic donation;" harnessing the willingness of relatives and friends to donate by addressing the many barriers which serve as disincentives to living donation...
October 1, 2017: Journal of Medicine and Philosophy
https://www.readbyqxmd.com/read/28922834/how-we-transmit-memories-to-other-brains-constructing-shared-neural-representations-via-communication
#16
A Zadbood, J Chen, Y C Leong, K A Norman, U Hasson
Humans are able to mentally construct an episode when listening to another person's recollection, even though they themselves did not experience the events. However, it is unknown how strongly the neural patterns elicited by mental construction resemble those found in the brain of the individual who experienced the original events. Using fMRI and a verbal communication task, we traced how neural patterns associated with viewing specific scenes in a movie are encoded, recalled, and then transferred to a group of naïve listeners...
October 1, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28922519/a-cost-minimisation-analysis-of-olive-oil-versus-hyperoxygenated-fatty-acid-treatment-for-the-prevention-of-pressure-ulcers-in-primary-health-care-a-randomised-controlled-trial
#17
Inmaculada Lupiañez-Pérez, Juan Carlos Morilla-Herrera, Shakira Kaknani-Uttumchanchandani, Yolanda Lupiañez-Perez, Magdalena Cuevas-Fernandez-Gallego, Francisco Martin-Santos, Jorge Caro-Bautista, Jose Miguel Morales-Asencio
Pressure ulcers represent a major current health problem and cause an important economic impact on the health care system. Most studies on the prevention of pressure ulcers have been carried out in hospital contexts, with respect to the use of hyperoxygenated fatty acids, and to date no studies have specifically examined the use of olive oil-based treatments. AIM: To evaluate the cost of using extra virgin olive oil, rather than hyperoxygenated fatty acids, in the prevention of pressure ulcers among persons with impaired mobility and receiving home care...
September 18, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28922348/stem-cell-biology-and-regenerative-medicine-for-neonatal-lung-diseases
#18
REVIEW
Martin Kang, Bernard Thébaud
Lung diseases remain one of the main causes of morbidity and mortality in neonates. Cell therapy and regenerative medicine have the potential to revolutionize the management of life-threatening and debilitating lung diseases that currently lack effective treatments. Over the past decade, the repair capabilities of stem/progenitor cells has been harnessed to prevent/rescue lung damage in experimental neonatal lung diseases. Mesenchymal stromal cells and amnion epithelial cells exert pleiotropic effects and represent ideal therapeutic cells for bronchopulmonary dysplasia, a multifactorial disease...
September 18, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28922326/the-smile-index-part-1-a-large-scale-study-of-phenotypic-norms-for-pre-and-post-operative-unilateral-cleft-lip
#19
Caroline A Yao, Thomas Imahiyerobo, Jordan Swanson, Allyn Auslander, Diego De Cardenas, Jane C Figueiredo, Meghan McCullough, Melinda Costa, Richard Vanderburg, William P Magee
BACKGROUND: Unilateral cleft lip has a spectrum of disease morphology but severity assessments are difficult given the absence of an accessible, objective assessment tools or reference data. We characterize the spectrum of cleft morphology before and after surgical repair for a large, multi-ethnic population using easily identifiable facial landmarks collected through a novel smart phone-based application. METHODS: Anthropometric measurements and standardized photographs were prospectively collected in Morocco, Bolivia, Vietnam and Madagascar during medical missions in 2015 utilizing an application designed specifically for the study...
September 14, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28922315/validation-of-fear-of-falling-and-balance-confidence-assessment-scales-in-persons-with-dystonia
#20
M J Boyce, L Lam, F Chang, N Mahant, V S C Fung, L Bradnam
BACKGROUND AND PURPOSE: Falls are problematic for people living with neurological disorders and a fear of falling can impact on actual falls. Fear of falling is commonly assessed using the Falls Self-Efficacy Scale International (FES-I) or the Activities-specific Balance Confidence (ABC) Scale. These scales can predict risk of falling. We aimed to validate the FES-I and the ABC in persons with dystonia. METHODS: We conducted an online survey of people with dystonia, collecting information on demographics, 6-month falls history, dystonia disability, and the FES-I and ABC scales...
October 2017: Journal of Neurologic Physical Therapy: JNPT
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