keyword
MENU ▼
Read by QxMD icon Read
search

CV

keyword
https://www.readbyqxmd.com/read/28941364/nonalcoholic-fatty-liver-disease-incidence-and-impact-on-metabolic-burden-and-death-a-20-year-community-study
#1
Alina M Allen, Therneau M Terry, Joseph J Larson, Alexandra Coward, Virend K Somers, Patrick S Kamath
Recent population-based data on nonalcoholic fatty liver disease (NAFLD) epidemiology in general and incidence in particular, are lacking. We examined trends in NAFLD incidence in a US community, and the impact of NAFLD on incident metabolic comorbidities (MC), cardiovascular (CV) events and mortality. A community cohort of all adults diagnosed with NAFLD in Olmsted County, MN between 1997-2014 was constructed using the Rochester Epidemiology Project database. The yearly incidence rate was calculated. The impact of NAFLD on incident MC, CV events and mortality was studied using a multi-state model, with a 4:1 age and sex-matched general population as reference...
September 23, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28941350/evaluation-of-analytical-performance-of-a-new-high-sensitivity-immunoassay-for-cardiac-troponin-i
#2
Silvia Masotti, Concetta Prontera, Veronica Musetti, Simona Storti, Rudina Ndreu, Gian Carlo Zucchelli, Claudio Passino, Aldo Clerico
BACKGROUND: The study aim was to evaluate and compare the analytical performance of the new chemiluminescent immunoassay for cardiac troponin I (cTnI), called Access hs-TnI using DxI platform, with those of Access AccuTnI+3 method, and high-sensitivity (hs) cTnI method for ARCHITECT platform. METHODS: The limits of blank (LoB), detection (LoD) and quantitation (LoQ) at 10% and 20% CV were evaluated according to international standardized protocols. For the evaluation of analytical performance and comparison of cTnI results, both heparinized plasma samples, collected from healthy subjects and patients with cardiac diseases, and quality control samples distributed in external quality assessment programs were used...
September 23, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28938132/development-and-validation-of-carbofuran-and-3-hydroxycarbofuran-analysis-by-high-pressure-liquid-chromatography-with-diode-array-detector-hplc-dad-for-forensic-veterinary-medicine
#3
Vagner Gonçalves, Nicolle Queiroz Hazarbassanov, Adriana de Siqueira, Jorge Camilo Florio, Claudia Helena Pastor Ciscato, Paulo Cesar Maiorka, Andre Fukushima, Helenice de Souza Spinosa
Agricultural pesticides used with the criminal intent to intoxicate domestic and wild animals are a serious concern in Veterinary Medicine. In order to identify the pesticide carbofuran and its metabolite 3- hydroxycarbofuran in animals suspected of exogenous intoxication a high pressure liquid chromatography with diode array detector (HPLC-DAD) method was developed and validated in stomach contents, liver, vitreous humor and blood. The method was evaluated using biological samples from seven different animal species...
September 14, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28937826/choroidal-variations-in-diabetic-macular-edema-fluorescein-angiography-and-optical-coherence-tomography
#4
Xiangning Wang, Shuting Li, Wei Li, Yanjun Hua, Qiang Wu
PURPOSES: To (i) evaluate variations in choroidal thickness (CT) and choroidal volume (CV) in diabetic macular edema (DME), as demonstrated by fluorescein angiography (FA) and enhanced depth-imaging (EDI) optical coherence tomography (OCT) (EDI-OCT) and (ii) correlate these variations with visual acuity. METHODS: This study was a retrospective observational case series of patients with diabetic retinopathy (DR) and DME. The study groups comprised 77 DR patients (n = 87), all of whom underwent color fundus photography, FA, and OCT on the same day...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937206/rod-like-sb2se3-wrapped-with-carbon-the-exploring-of-electrochemical-properties-in-sodium-ion-batteries
#5
Peng Ge, Xiao-Yu Cao, Hongshuai Hou, Sijie Li, Xiaobo Ji
One-dimensional Sb2Se3/C rods are prepared through self-assembly from the inducing of anisotropy, and the corresponding sodium storage behaviors are evaluated, presenting excellent electrochemical performances with superior cycle stability and rate capability. The Sb2Se3 delivers a high initial charge capacity of 657.6 mAh g-1 at current density of 0.2 A g-1 between 2.5 and 0.01 V. After 100 cycles, the reversible capacity of Sb2Se3/C remain 485.2 mAh g-1. Even at high rate current density of 2.0 A g-1, the charge capacity still remains 311...
September 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28936690/correlation-and-agreement-between-language-environment-analysis-lena%C3%A2-and-manual-transcription-for-dutch-natural-language-recordings
#6
Tobias Busch, Anouk Sangen, Filiep Vanpoucke, Astrid van Wieringen
The Language ENvironment Analysis system (LENA™) automatically analyzes the natural sound environments of children. Among other things, it estimates the amounts of adult words (AWC), child vocalizations (CV), conversational turns (CT), and electronic media (TV) that a child is exposed to. To assess LENA's reliability, we compared it to manual transcription. Specifically, we calculated the correlation and agreement between the LENA estimates and manual counts for 48 five-min audio samples. These samples were selected from eight day-long recordings of six Dutch-speaking children (ages 2-5)...
September 21, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28936665/phosphoprotein-enrichment-from-tobacco-mature-pollen-crude-protein-extract
#7
Jan Fíla, David Honys
Protein phosphorylation was repeatedly shown to be the most dynamic post-translational modification mediated by a huge orchestra of protein kinases and phosphatases. Upon landing on a stigma, pollen grain dehydration and activation are accompanied by changes in protein phosphorylation together with the translation activation of stored mRNAs. To enable studies of the total phosphoproteome, it is usually necessary to apply various enrichment techniques. In this chapter, one of these protocols that worked previously well on tobacco mature pollen is presented in more detail...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28935895/absolute-quantitation-of-disease-protein-biomarkers-in-a-single-lc-ms-acquisition-using-apolipoprotein-f-as-an-example
#8
Abhinav Kumar, Bevin Gangadharan, Jeremy Cobbold, Mark Thursz, Nicole Zitzmann
LC-MS and immunoassay can detect protein biomarkers. Immunoassays are more commonly used but can potentially be outperformed by LC-MS. These techniques have limitations including the necessity to generate separate calibration curves for each biomarker. We present a rapid mass spectrometry-based assay utilising a universal calibration curve. For the first time we analyse clinical samples using the HeavyPeptide IGNIS kit which establishes a 6-point calibration curve and determines the biomarker concentration in a single LC-MS acquisition...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28934223/ursodeoxycholic-acid-prevents-ventricular-conduction-slowing-and-arrhythmia-by-restoring-t-type-calcium-current-in-fetuses-during-cholestasis
#9
Oladipupo Adeyemi, Anita Alvarez-Laviada, Francisca Schultz, Effendi Ibrahim, Michael Trauner, Catherine Williamson, Alexey V Glukhov, Julia Gorelik
BACKGROUND: Increased maternal serum bile acid concentrations in intrahepatic cholestasis of pregnancy (ICP) are associated with fetal cardiac arrhythmias. Ursodeoxycholic acid (UDCA) has been shown to demonstrate anti-arrhythmic properties via preventing ICP-associated cardiac conduction slowing and development of reentrant arrhythmias, although the cellular mechanism is still being elucidated. METHODS: High-resolution fluorescent optical mapping of electrical activity and electrocardiogram measurements were used to characterize effects of UDCA on one-day-old neonatal and adult female Langendorff-perfused rat hearts...
2017: PloS One
https://www.readbyqxmd.com/read/28934007/herbicidal-activity-of-slow-release-herbicide-formulations-in-wheat-stands-infested-by-weeds
#10
Natalia Zhila, Anastasiya Murueva, Anna Shershneva, Ekaterina Shishatskaya, Tatiana Volova
The present study reports the herbicidal activity of metribuzin and tribenuron-methyl embedded in the degradable matrix of natural poly-3-hydroxybutyrate [P(3HB)/MET and P(3HB)/TBM]. The developed formulations were constructed as films and microgranules, which were tested against the weeds such as white sweet clover Melilotus albus and lamb's quarters Chenopodium album in the presence of soft spring wheat (Triticum aestivum, cv. Altaiskaya 70) as the subject crop for investigation. The activity was measured in laboratory scale experiments by determining the density and weight of the vegetative organs of weeds...
September 21, 2017: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://www.readbyqxmd.com/read/28933773/rapid-quantification-of-major-volatile-metabolites-in-fermented-food-and-beverages-using-gas-chromatography-mass-spectrometry
#11
Farhana R Pinu, Silas G Villas-Boas
Here we present a method for the accurate quantification of major volatile metabolites found in different food and beverages, including ethanol, acetic acid and other aroma compounds, using gas chromatography coupled to mass spectrometry (GC-MS). The method is combined with a simple sample preparation procedure using sodium chloride and anhydrous ethyl acetate. The GC-MS analysis was accomplished within 4.75 min, and over 80 features were detected, of which 40 were positively identified using an in-house and a commercialmass spectrometry (MS) library...
July 26, 2017: Metabolites
https://www.readbyqxmd.com/read/28933756/a-disposable-amperometric-sensor-based-on-high-performance-pedot-pss-ionic-liquid-nanocomposite-thin-film-modified-screen-printed-electrode-for-the-analysis-of-catechol-in-natural-water-samples
#12
Francis D Krampa, Yaw Aniweh, Gordon A Awandare, Prosper Kanyong
A conducting polymer-based composite material of poly(3,4-ethylenedioxythiophene) (PEDOT): poly(4-styrenesulfonate) (PSS) doped with different percentages of a room temperature ionic liquid (IL), 1-ethyl-3-methylimidazolium tetrafluoroborate ([EMIM][BF₄]), was prepared and a very small amount of the composite (2.0 µL) was drop-coated on the working area of a screen-printed carbon electrode (SPCE). The SPCE, modified with PEDOT:PSS/IL composite thin-film, was characterized by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), profilometry and sessile contact angle measurements...
July 26, 2017: Sensors
https://www.readbyqxmd.com/read/28933711/the-effect-of-hip-joint-angle-on-isometric-midthigh-pull-kinetics
#13
Thomas DosʼSantos, Christopher Thomas, Paul A Jones, John J McMahon, Paul Comfort
Dos'Santos, T, Thomas, C, Jones, PA, McMahon, JJ, and Comfort, P. The effect of hip joint angle on isometric midthigh pull kinetics. J Strength Cond Res 31(10): 2748-2757, 2017-The aim of this study were to compare isometric midthigh pull (IMTP) peak force (PF), time-specific force values (100-, 150-, and 200 ms), rate of force development (RFD) at predetermined time bands (0-100, 0-150, and 0-200 ms) and net forces between 2 commonly adopted hip joint angles (145°[hip145] and 175°[hip175]) with a 145° standardized knee angle...
October 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28933655/cerebrovascular-reactivity-measurement-in-cerebral-small-vessel-disease-rationale-and-reproducibility-of-a-protocol-for-mri-acquisition-and-image-processing
#14
Michael J Thrippleton, Yulu Shi, Gordon Blair, Iona Hamilton, Gordon Waiter, Christian Schwarzbauer, Cyril Pernet, Peter Jd Andrews, Ian Marshall, Fergus Doubal, Joanna M Wardlaw
Background Impaired autoregulation may contribute to the pathogenesis of cerebral small vessel disease. Reliable protocols for measuring microvascular reactivity are required to test this hypothesis and for providing secondary endpoints in clinical trials. Aims To develop and assess a protocol for acquisition and processing of cerebrovascular reactivity by MRI, in subcortical tissue of patients with small vessel disease and minor stroke. Methods We recruited 15 healthy volunteers, testing paradigms using 1- and 3-min 6% CO2 challenges with repeat scanning, and 15 patients with history of minor stroke...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28932906/safety-study-and-therapeutic-drug-monitoring-of-the-oral-tablet-formulation-of-posaconazole-in-patients-with-haematological-malignancies
#15
C Boglione-Kerrien, S Picard, C Tron, S Nimubona, J-P Gangneux, S Lalanne, F Lemaitre, E Bellissant, M-C Verdier, A Petitcollin
PURPOSE: Posaconazole is a triazole antifungal widely used for prophylaxis of invasive fungal disease (IFI). Posaconazole tablets allow reaching higher plasma levels than the oral suspension, but safety data with this formulation in real life are scarce. This study aimed at evaluating the safety profile, the pharmacokinetic variability, and the concentration-toxicity relationship of posaconazole tablets in patients with haematological malignancies. METHODS: Sixty neutropenic patients treated with posaconazole tablets for prophylaxis of IFI were prospectively included in the study...
September 20, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28931948/abnormal-arterial-venous-fusions-and-fate-specification-in-mouse-embryos-lacking-blood-flow
#16
Jennifer J Hwa, Nathan Beckouche, Lawrence Huang, Yoseph Kram, Henrik Lindskog, Rong A Wang
The functions of blood flow in the morphogenesis of mammalian arteries and veins are not well understood. We examined the development of the dorsal aorta (DA) and the cardinal vein (CV) in Ncx1 (-/-) mutants, which lack blood flow due to a deficiency in a sodium calcium ion exchanger expressed specifically in the heart. The mutant DA and CV were abnormally connected. The endothelium of the Ncx1 (-/-) mutant DA lacked normal expression of the arterial markers ephrin-B2 and Connexin-40. Notch1 activation, known to promote arterial specification, was decreased in mutant DA endothelial cells (ECs), which ectopically expressed the venous marker Coup-TFII...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931867/accuracy-and-reliability-of-cone-beam-computed-tomography-for-linear-and-volumetric-mandibular-condyle-measurements-a-human-cadaver-study
#17
Verónica García-Sanz, Carlos Bellot-Arcís, Virginia Hernández, Pedro Serrano-Sánchez, Juan Guarinos, Vanessa Paredes-Gallardo
The accuracy of Cone-Beam Computed Tomography (CBCT) on linear and volumetric measurements on condyles has only been assessed on dry skulls. The aim of this study was to evaluate the reliability and accuracy of linear and volumetric measurements of mandibular condyles in the presence of soft tissues using CBCT. Six embalmed cadaver heads were used. CBCT scans were taken, followed by the extraction of the condyles. The water displacement technique was used to calculate the volumes of the condyles and three linear measurements were made using a digital caliper, these measurements serving as the gold standard...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28930882/reproducibility-of-bruch-s-membrane-opening-minimum-rim-width-measurements-with-spectral-domain-optical-coherence-tomography
#18
Keunheung Park, Jinmi Kim, Jiwoong Lee
PURPOSE: To evaluate the reproducibility of Bruch's membrane opening-minimum rim width (BMO-MRW) measurements obtained with Spectralis optical coherence tomography (OCT) in normal and glaucoma subjects. METHODS: In total, 123 eyes from 123 subjects (65 healthy, 58 glaucoma subjects) were included. BMO-MRW measurements were repeated three times during the same visit using Spectralis OCT. The BMO points and internal limiting membrane were identified with automated software and corrected manually when necessary...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28930871/reliability-and-measurement-error-of-tensiomyography-to-assess-mechanical-muscle-function-a-systematic-review
#19
Saúl Martín-Rodríguez, Irineu Loturco, Angus M Hunter, David Rodríguez-Ruiz, Diego Munguia-Izquierdo
Interest in studying mechanical skeletal muscle function through tensiomyography (TMG) has increased in recent years. This systematic review aimed to (a) report the reliability and measurement error of all TMG parameters [i.e., maximum radial displacement of the muscle belly (Dm), contraction time (Tc), delay time (Td), half-relaxation time (½ Tr), and sustained contraction time (Ts)] and (b) to provide critical reflection on how to perform accurate and appropriate measurements for informing clinicians, exercise professionals, and researchers...
September 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28930862/an-innovative-ergometer-to-measure-neuromuscular-fatigue-immediately-after-cycling
#20
Douglas Doyle-Baker, John Temesi, Mary E Medysky, Robert J Holash, Guillaume Y Millet
PURPOSE: When assessing neuromuscular fatigue (NMF) from dynamic exercise using large muscle mass (e.g. cycling), most studies have delayed measurement for 1-3 min after task failure. This study aimed to determine the reliability of an innovative cycling ergometer permitting the start of fatigue measurement within 1 s after cycling. METHODS: Twelve subjects participated in two experimental sessions. Knee-extensor NMF was assessed by electrical nerve and transcranial magnetic stimulation with both a traditional chair set-up (PRE and POST-Chair, 2 min post-exercise) and the new cycling ergometer (PRE, every 3 min during incremental exercise and POST-Bike, at task failure)...
September 19, 2017: Medicine and Science in Sports and Exercise
keyword
keyword
90548
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"