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https://www.readbyqxmd.com/read/28916874/development-of-cacta-transposon-derived-scar-markers-and-their-use-in-population-structure-analysis-in-zea-mays
#1
Neha Samir Roy, Kyong-Cheul Park, Sung-Il Lee, Min-Ji Im, Rahul Vasudeo Ramekar, Nam-Soo Kim
Molecular marker technologies have proven to be an important breakthrough for genetic studies, construction of linkage maps and population genetics analysis. Transposable elements (TEs) constitute major fractions of repetitive sequences in plants and offer a wide range of possible areas to be explored as molecular markers. Sequence characterized amplified region (SCAR) marker development provides us with a simple and time saving alternative approach for marker development. We employed the CACTA-TD to develop SCARs and then integrated them into linkage map and used them for population structure and genetic diversity analysis of corn inbred population...
September 15, 2017: Genetica
https://www.readbyqxmd.com/read/28913621/what-do-we-mean-by-physician-wellness-a-systematic-review-of-its-definition-and-measurement
#2
REVIEW
Keri J S Brady, Mickey T Trockel, Christina T Khan, Kristin S Raj, Mary Lou Murphy, Bryan Bohman, Erica Frank, Alan K Louie, Laura Weiss Roberts
OBJECTIVE: Physician wellness (well-being) is recognized for its intrinsic importance and impact on patient care, but it is a construct that lacks conceptual clarity. The authors conducted a systematic review to characterize the conceptualization of physician wellness in the literature by synthesizing definitions and measures used to operationalize the construct. METHODS: A total of 3057 references identified from PubMed, Web of Science, and a manual reference check were reviewed for studies that quantitatively assessed the "wellness" or "well-being" of physicians...
September 14, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/28910267/surveillance-for-certain-health-behaviors-and-conditions-among-states-and-selected-local-areas-behavioral-risk-factor-surveillance-system-united-states-2013-and-2014
#3
Sonya Gamble, Tebitha Mawokomatanda, Fang Xu, Pranesh P Chowdhury, Carol Pierannunzi, David Flegel, William Garvin, Machell Town
PROBLEM: Chronic diseases and conditions (e.g., heart diseases, stroke, arthritis, and diabetes) are the leading causes of morbidity and mortality in the United States. These conditions are costly to the U.S. economy, yet they are often preventable or controllable. Behavioral risk factors (e.g., excessive alcohol consumption, tobacco use, poor diet, frequent mental distress, and insufficient sleep) are linked to the leading causes of morbidity and mortality. Adopting positive health behaviors (e...
September 15, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/28904631/do-research-papers-provide-enough-information-on-design-and-material-used-in-ankle-foot-orthoses-for-children-with-cerebral-palsy-a-systematic-review
#4
N Eddison, M Mulholland, N Chockalingam
OBJECTIVES: The purpose of this article is to determine how many of the current peer-reviewed studies of ankle foot or-thoses (AFOs) on children with cerebral palsy (CP) have included adequate details of the design and material of the AFO, to enable the study to be reproduced and outcomes clearly understood. METHODS: A thorough search of studies published in English was conducted in March 2015, with no restriction on dates, within all major databases using relevant phrases...
August 1, 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28903836/reconsidering-a-lower-level-of-follicle-stimulating-hormone-as-abnormal-in-sub-fertile-males-of-pakistan
#5
Shehla Arif, Ayesha Khan
OBJECTIVE: To assess the association between Follicle-Stimulating Hormone (FSH) and semen parameters in order to evaluate whether the current laboratory reference for abnormal FSH levels should be readjusted. STUDY DESIGN: Observational, cross-sectional study. PLACE AND DURATION OF STUDY: Infertility Clinic of Gynecology Unit 1, Civil Hospital, Karachi, from May 2015 to April 2016. METHODOLOGY: The study included 100 sub-fertile males inducted from the clinic...
August 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28901865/penile-and-testicular-measurements-in-male-neonates-and-infants-single-center-egyptian-study
#6
Adel A Hagag, Adel A Erfan, Shaymaa M Elrifaey, Rasha M Gamal, Ahmed I Harakan
BACKGROUND: Universal reference values of penile length, circumferences and testicular volume in newborns and infants are inappropriate to be used in variable ethnic backgrounds. OBJECTIVE: The aim of this prospective study was to establish normal reference values for stretched penile length, penile circumference and testicular volume for Egyptian newborn and infants. SUBJECTS AND METHODS: This observational cross-sectional study included 1850 healthy male full term newborn and infants applied for routine check-up, aged 0 -24 months, the newborn and infants were recruited from Tanta University Hospital in the period from July 2015 to January 2017...
September 12, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28901694/the-role-of-cognitive-biases-in-short-term-psychodynamic-psychotherapy
#7
Ueli Kramer, Diana Ortega, Gilles Ambresin, Jean-Nicolas Despland, Yves de Roten
The concept of biased thinking - or cognitive biases - is relevant to psychotherapy research and clinical conceptualization, beyond cognitive theories. The present naturalistic study aimed to examine the changes in biased thinking over the course of a short-term dynamic psychotherapy (STDP) and to discover potential links between these changes and symptomatic improvement. This study focuses on 32 self-referred patients consulting for Adjustment Disorder according to DSM-IV-TR. The therapists were experienced psychodynamically oriented psychiatrists and psychotherapists...
September 13, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28901255/health-benefits-of-manuka-honey-as-an-essential-constituent-for-tissue-regeneration
#8
Kamal Niaz, Faheem Maqbool, Haji Bahadar, Mohammad Abdollahi
Honey is known for its therapeutic properties from ancient civilizations but only since last few decades its mechanism has been studied on how it causes epithelial regeneration leading to wound and ulcer healing.. In the present review the health perspectives of honey, its chemical composition with special reference to flavonoids, polyphenol composition and other bioactive trace compounds used in tissue regeneration have been highlighted. Honey can inhibit carcinogenesis by moderating with molecular processes of initiation, advancement and progression stage of cancer cells, therefore it is considered a promising anti-cancer agent...
September 11, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28901007/pharmacological-and-mechanical-interventions-for-labour-induction-in-outpatient-settings
#9
REVIEW
Joshua P Vogel, Alfred O Osoti, Anthony J Kelly, Stefania Livio, Jane E Norman, Zarko Alfirevic
BACKGROUND: Induction of labour is carried out for a variety of indications and using a range of methods. For women at low risk of pregnancy complications, some methods of induction of labour or cervical ripening may be suitable for use in outpatient settings. OBJECTIVES: To examine pharmacological and mechanical interventions to induce labour or ripen the cervix in outpatient settings in terms of effectiveness, maternal satisfaction, healthcare costs and, where information is available, safety...
September 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28898390/comprehensive-geriatric-assessment-for-older-adults-admitted-to-hospital
#10
REVIEW
Graham Ellis, Mike Gardner, Apostolos Tsiachristas, Peter Langhorne, Orlaith Burke, Rowan H Harwood, Simon P Conroy, Tilo Kircher, Dominique Somme, Ingvild Saltvedt, Heidi Wald, Desmond O'Neill, David Robinson, Sasha Shepperd
BACKGROUND: Comprehensive geriatric assessment (CGA) is a multi-dimensional, multi-disciplinary diagnostic and therapeutic process conducted to determine the medical, mental, and functional problems of older people with frailty so that a co-ordinated and integrated plan for treatment and follow-up can be developed. This is an update of a previously published Cochrane review. OBJECTIVES: We sought to critically appraise and summarise current evidence on the effectiveness and resource use of CGA for older adults admitted to hospital, and to use these data to estimate its cost-effectiveness...
September 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28894638/is-there-genetic-variation-in-mycorrhization-of-medicago-truncatula
#11
Dorothée Dreher, Heena Yadav, Sindy Zander, Bettina Hause
Differences in the plant's response among ecotypes or accessions are often used to identify molecular markers for the respective process. In order to analyze genetic diversity of Medicago truncatula in respect to interaction with the arbuscular mycorrhizal (AM) fungus Rhizophagus irregularis, mycorrhizal colonization was evaluated in 32 lines of the nested core collection representing the genetic diversity of the SARDI collection. All studied lines and the reference line Jemalong A17 were inoculated with R...
2017: PeerJ
https://www.readbyqxmd.com/read/28892556/parenteral-anticoagulation-in-ambulatory-patients-with-cancer
#12
REVIEW
Elie A Akl, Lara A Kahale, Maram B Hakoum, Charbel F Matar, Francesca Sperati, Maddalena Barba, Victor E D Yosuico, Irene Terrenato, Anneliese Synnot, Holger Schünemann
BACKGROUND: Anticoagulation may improve survival in patients with cancer through a speculated anti-tumour effect, in addition to the antithrombotic effect, although may increase the risk of bleeding. OBJECTIVES: To evaluate the efficacy and safety of parenteral anticoagulants in ambulatory patients with cancer who, typically, are undergoing chemotherapy, hormonal therapy, immunotherapy or radiotherapy, but otherwise have no standard therapeutic or prophylactic indication for anticoagulation...
September 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28891275/cigarette-smoking-as-a-risk-factor-for-the-development-of-and-mortality-from-hepatocellular-carcinoma-an-updated-systematic-review-of-81-epidemiological-studies
#13
Omar Abdel-Rahman, Daniel Helbling, Othmar Schöb, Mostafa Eltobgy, Hadeer Mohamed, Jan Schmidt, Anwar Giryes, Arianeb Mehrabi, Satheesh Iype, Hannah John, Aysun Tekbas, Ahmad Zidan, Hani Oweira
BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and its incidence has increased during the past decade. While hepatitis B and C virus infections and alcohol were established risk factors, the impact of smoking on the incidence and mortality of HCC was needed to be confirmed. METHODS: We reviewed cohort and case-control studies evaluating the association between cigarette smoking and incidence and mortality of HCC from MEDLINE and Google Scholar...
September 10, 2017: Journal of Evidence-based Medicine
https://www.readbyqxmd.com/read/28886607/impact-of-clinical-registries-on-quality-of-patient-care-and-clinical-outcomes-a-systematic-review
#14
Dewan Md Emdadul Hoque, Varuni Kumari, Masuma Hoque, Rasa Ruseckaite, Lorena Romero, Sue M Evans
BACKGROUND: Clinical quality registries (CQRs) are playing an increasingly important role in improving health outcomes and reducing health care costs. CQRs are established with the purpose of monitoring quality of care, providing feedback, benchmarking performance, describing pattern of treatment, reducing variation and as a tool for conducting research. OBJECTIVES: To synthesise the impact of clinical quality registries (CQRs) as an 'intervention' on (I) mortality/survival; (II) measures of outcome that reflect a process or outcome of health care; (III) health care utilisation; and (IV) healthcare-related costs...
2017: PloS One
https://www.readbyqxmd.com/read/28884785/certolizumab-pegol-cdp870-for-rheumatoid-arthritis-in-adults
#15
REVIEW
Vicente Ruiz Garcia, Amanda Burls, Juan B Cabello, Paloma Vela Casasempere, Sylvia Bort-Marti, José A Bernal
BACKGROUND: Tumour necrosis factor (TNF)-alpha inhibitors are beneficial for the treatment of rheumatoid arthritis (RA) for reducing the risk of joint damage, improving physical function and improving the quality of life. This review is an update of the 2014 Cochrane Review of the treatment of RA with certolizumab pegol. OBJECTIVES: To assess the clinical benefits and harms of certolizumab pegol (CZP) in people with RA who have not responded well to conventional disease-modifying anti-rheumatic drugs (DMARDs)...
September 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28884158/a-geo-coded-inventory-of-anophelines-in-the-afrotropical-region-south-of-the-sahara-1898-2016
#16
David Kyalo, Punam Amratia, Clara W Mundia, Charles M Mbogo, Maureen Coetzee, Robert W Snow
Background: Understanding the distribution of anopheline vectors of malaria is an important prelude to the design of national malaria control and elimination programmes. A single, geo-coded continental inventory of anophelines using all available published and unpublished data has not been undertaken since the 1960s. Methods: We have searched African, European and World Health Organization archives to identify unpublished reports on anopheline surveys in 48 sub-Saharan Africa countries. This search was supplemented by identification of reports that formed part of post-graduate theses, conference abstracts, regional insecticide resistance databases and more traditional bibliographic searches of peer-reviewed literature...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/28881006/simple-aspiration-versus-intercostal-tube-drainage-for-primary-spontaneous-pneumothorax-in-adults
#17
REVIEW
Kristin V Carson-Chahhoud, Abel Wakai, Joseph Em van Agteren, Brian J Smith, Grainne McCabe, Malcolm P Brinn, Ronan O'Sullivan
BACKGROUND: For management of pneumothorax that occurs without underlying lung disease, also referred to as primary spontaneous pneumothorax, simple aspiration is technically easier to perform than intercostal tube drainage. In this systematic review, we seek to compare the clinical efficacy and safety of simple aspiration versus intercostal tube drainage for management of primary spontaneous pneumothorax. This review was first published in 2007 and was updated in 2017. OBJECTIVES: To compare the clinical efficacy and safety of simple aspiration versus intercostal tube drainage for management of primary spontaneous pneumothorax...
September 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28880995/vitamin-a-supplements-for-reducing-mother-to-child-hiv-transmission
#18
REVIEW
Charles S Wiysonge, Valantine N Ndze, Eugene J Kongnyuy, Muki S Shey
BACKGROUND: Strategies to reduce the risk of mother-to-child transmission of the human immunodeficiency virus (HIV) include lifelong antiretroviral therapy (ART) for HIV-positive women, exclusive breastfeeding from birth for six weeks plus nevirapine or replacement feeding plus nevirapine from birth for four to six weeks, elective Caesarean section delivery, and avoiding giving children chewed food. In some settings, these interventions may not be practical, feasible, or affordable. Simple, inexpensive, and effective interventions (that could potentially be implemented even in the absence of prenatal HIV testing programmes) would be valuable...
September 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28880761/predictive-validity-of-the-braden-scale-for-assessing-risk-of-developing-pressure-ulcers-and-dependence-related-lesions
#19
A Roca-Biosca, L Rubio-Rico, M I de Molina Fernández, N García Grau, G Tuset Garijo, F P García Fernández
OBJECTIVE: In 2014, a new theoretical model explained the mechanism of the development of pressure ulcers (PUs) and that of seven types of lesions known as dependence-related lesions (DRL). The aim of this study was to calculate the incidence of DRL that have been classified as PUs and to check the predictive validity of the Braden scale for assessing DRL in accordance with the new theoretical model in an intensive care unit (ICU). Method This longitudinal, prospective study was conducted in a Spanish ICU...
September 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28880568/macro-and-micronutrients-of-human-milk-composition-are-they-related-to-maternal-diet-a-comprehensive-systematic-review
#20
Mojtaba Keikha, Maryam Bahreynian, Mohammad Saleki, Roya Kelishadi
BACKGROUND: This study aims at systematically reviewing the observational and interventional studies on the association of maternal macro- and micronutrient intake with breast milk content. METHODS: We systematically searched the Medline via PubMed, Scopus, and ISI Web of Knowledge till October 2016 with the following search strategy: ("human milk" OR "breast milk" OR "breast milk composition" OR "human breast milk composition" OR "composition breast milk" OR "mother milk" OR "human breast milk") AND ("maternal diet" OR "maternal nutrition")...
September 7, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
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