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https://www.readbyqxmd.com/read/27907015/weight-gain-in-survivors-living-in-temporary-housing-in-the-tsunami-stricken-area-during-the-recovery-phase-following-the-great-east-japan-earthquake-and-tsunami
#1
Shuko Takahashi, Yuki Yonekura, Ryohei Sasaki, Yukari Yokoyama, Kozo Tanno, Kiyomi Sakata, Akira Ogawa, Seichiro Kobayashi, Taro Yamamoto
INTRODUCTION: Survivors who lost their homes in the Great East Japan Earthquake and Tsunami were forced to live in difficult conditions in temporary housing several months after the disaster. Body weights of survivors living in temporary housing for a long period might increase due to changes in their life style and psychosocial state during the medium-term and long-term recovery phases. The aim of this study was to determine whether there were differences between body weight changes of people living in temporary housing and those not living in temporary housing in a tsunami-stricken area during the medium-term and long-term recovery phases...
2016: PloS One
https://www.readbyqxmd.com/read/27903397/-association-between-hematocrit-and-risk-of-incident-hypertension-a-cohort-study
#2
Y F Chen, C X Wang, Z S Yuan, W C Zhang, Y F Liu, X Y Li, Alimu Dayimu, Y B Xu, F Z Xue, C Q Zhang
Objective: To explore the association between hematocrit level and risk of incident hypertension. Method: Subjects who participated at least two times routine health check-up in Health Management Center of Shandong Province Hospital between January 2005 and January 2010 were eligible for inclusion. After excluding participants with known hypertension and other related diseases, a prospective cohort with 20 606 subjects (female: 8 218, male: 12 388) was established. Cox-proportional hazard model was used to assess the association between hematocrit and the development of hypertension for female and male respectively...
November 24, 2016: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/27900547/estimating-prevalence-of-functional-iron-deficiency-anaemia-in-advanced-cancer
#3
Karen Neoh, Simon Stanworth, Sant-Rayn Pasricha, Michael I Bennett
PURPOSE: Anaemia is a common complication of cancer causing symptoms including fatigue. It is also associated with shorter survival. Cancer causes systemic inflammation which interrupts iron metabolism leading to a functional iron deficiency (FID). There are few data on prevalence or aetiology of anaemia in those with advanced cancer. We aimed to establish the prevalence of anaemia and estimate extent of FID anaemia in patients with advanced cancer. METHODS: All patients with advanced cancer referred to two UK specialist palliative care services over 1 year were identified...
November 29, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/27899001/drug-interventions-for-the-treatment-of-obesity-in-children-and-adolescents
#4
REVIEW
Emma Mead, Greg Atkinson, Bernd Richter, Maria-Inti Metzendorf, Louise Baur, Nicholas Finer, Eva Corpeleijn, Claire O'Malley, Louisa J Ells
BACKGROUND: Child and adolescent obesity has increased globally, and can be associated with significant short- and long-term health consequences. OBJECTIVES: To assess the efficacy of drug interventions for the treatment of obesity in children and adolescents. SEARCH METHODS: We searched CENTRAL, MEDLINE, Embase, PubMed (subsets not available on Ovid), LILACS as well as the trial registers ICTRP (WHO) and ClinicalTrials.gov. Searches were undertaken from inception to March 2016...
November 29, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27893523/variable-size-bead-layer-as-standard-reference-for-endothelial-microscopes
#5
Simona Tufo, Erica Prazzoli, Lorenzo Ferraro, Federica Cozza, Alessandro Borghesi, Silvia Tavazzi
PURPOSE: For morphometric analysis of the cell mosaic of corneal endothelium, checking accuracy and precision of instrumentation is a key step. In this study, a standard reference sample is proposed, developed to reproduce the cornea with its shape and the endothelium with its intrinsic variability in the cell size. METHODS: A polystyrene bead layer (representing the endothelium) was deposited on a lens (representing the cornea). Bead diameters were 20, 25, and 30 μm (fractions in number 55%, 30%, and 15%, respectively)...
November 23, 2016: Cornea
https://www.readbyqxmd.com/read/27892744/evaluation-of-efficacy-and-safety-of-different-pembrolizumab-dose-schedules-in-treatment-of-non-small-cell-lung-cancer-and-melanoma-a-systematic-review
#6
Omar Abdel-Rahman
AIM: Pembrolizumab is a fully humanized anti-PD-1 agent currently approved for the treatment of advanced melanoma and pretreated non-small-cell lung cancer (NSCLC). OBJECTIVE: To assess the efficacy and safety of different dose schedules of pembrolizumab in the treatment of patients with advanced NSCLC and melanoma. Search method: MEDLINE database has been searched. Reference lists of original studies and review articles were checked for other related articles. SELECTION CRITERIA: Prospective clinical trials reporting the outcomes of more than one dose schedule of pembrolizumab in the treatment of advanced NSCLC and melanoma...
November 28, 2016: Immunotherapy
https://www.readbyqxmd.com/read/27885658/early-skin-to-skin-contact-for-mothers-and-their-healthy-newborn-infants
#7
REVIEW
Elizabeth R Moore, Nils Bergman, Gene C Anderson, Nancy Medley
BACKGROUND: Mother-infant separation post birth is common. In standard hospital care, newborn infants are held wrapped or dressed in their mother's arms, placed in open cribs or under radiant warmers. Skin-to-skin contact (SSC) begins ideally at birth and should last continually until the end of the first breastfeeding. SSC involves placing the dried, naked baby prone on the mother's bare chest, often covered with a warm blanket. According to mammalian neuroscience, the intimate contact inherent in this place (habitat) evokes neuro-behaviors ensuring fulfillment of basic biological needs...
November 25, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27885212/let-s-try-to-determine-the-original-reference-value-of-highly-stress-on-stress-check-program
#8
Takahiro Yamashita
No abstract text is available yet for this article.
November 23, 2016: Sangyō Eiseigaku Zasshi, Journal of Occupational Health
https://www.readbyqxmd.com/read/27884579/number-of-daily-antihypertensive-drugs-and-the-risk-of-osteoporotic-fractures-in-older-hypertensive-adults-national-health-insurance-service-senior-cohort
#9
So Yeon Kim, Sunyoung Kim, Sung Eun Choi, Byung Sung Kim, Hyun Rim Choi, Deri Hwang, Chang Won Won
BACKGROUND: Antihypertensive medication represents one of the most common prescriptions for senior individuals. Numerous studies have assessed the influence of antihypertensive treatment on the risk for osteoporotic fracture, yet much controversy remains. We analyzed the relationship between the incidence of osteoporotic fracture and the average number of daily antihypertensive drugs (NDAD) included in the prescription of elderly hypertensive patients. METHODS: The study population was derived from the National Health Insurance Service-Senior Cohort (2002-2013), and consisted of elderly patients (≥60 years) diagnosed with hypertension in 2009, who did not have osteoporotic fractures in 2008, and underwent at least one national health check-up between 2009 and 2013, and had complete records after 2010...
November 21, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27876899/check-list-of-parasites-and-bacteria-recorded-from-pangolins-manis-sp
#10
REVIEW
Rajesh Kumar Mohapatra, Sudarsan Panda, Manoj V Nair, Lakshmi Narayan Acharjyo
Sound knowledge on parasite fauna of pangolins is crucial for evaluation of their health status. In the present review, a checklist of 34 genera of parasites and bacteria, including 4 genera of protozoan, 13 genera of helminthes, 8 genera of ticks, 2 genera of mites and 7 genera of bacteria reported from pangolins was compiled and their zoonotic potential were discussed. The aim of this checklist is to underline the information gap and to provide a reference list of parasites and bacteria known for pangolins to assist in their further investigation...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27876230/intercalated-chemotherapy-and-epidermal-growth-factor-receptor-inhibitors-for-patients-with-advanced-non-small-cell-lung-cancer-a-systematic-review-and-meta-analysis
#11
REVIEW
Anna La Salvia, Antonio Rossi, Domenico Galetta, Elisa Gobbini, Emmanuele De Luca, Silvia Novello, Massimo Di Maio
Randomized clinical trials (RCTs) of concurrent epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) plus chemotherapy for unselected patients with advanced non-small-cell lung cancer (NSCLC) produced negative results. Intercalated administration could avoid the reduction of chemotherapy activity due to G1 cell-cycle arrest from EGFR-TKIs. A PubMed search was performed in December 2015 and updated in February 2016. The references from the selected studies were also checked to identify additional eligible trials...
October 28, 2016: Clinical Lung Cancer
https://www.readbyqxmd.com/read/27875631/intravenous-nutrients-for-preventing-inadvertent-perioperative-hypothermia-in-adults
#12
REVIEW
Sheryl Warttig, Phil Alderson, Sharon R Lewis, Andrew F Smith
BACKGROUND: Inadvertent perioperative hypothermia (a drop in core temperature to below 36°C) occurs because normal temperature regulation is disrupted during surgery, mainly because of the effects of anaesthetic drugs and exposure of the skin for prolonged periods. Many different ways of maintaining body temperature have been proposed, one of which involves administration of intravenous nutrients during the perioperative period that may reduce heat loss by increasing metabolism, thereby increasing heat production...
November 22, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27875332/local-electronic-structure-and-nanolevel-hierarchical-organization-of-bone-tissue-theory-and-nexafs-study
#13
A A Pavlychev, A S Avrunin, A S Vinogradov, E O Filatova, A A Doctorov, Yu S Krivosenko, D O Samoilenko, G I Svirskiy, A S Konashuk, D A Rostov
Theoretical and experimental investigations of native bone are carried out to understand relationships between its hierarchical organization and local electronic and atomic structure of the mineralized phase. The 3D superlattice model of a coplanar assembly of the hydroxyapatite (HAP) nanocrystallites separated by the hydrated nanolayers is introduced to account the interplay of short-, long- and super-range order parameters in bone tissue. The model is applied to (i) predict and rationalize the HAP-to-bone spectral changes in the electronic structure and (ii) describe the mechanisms ensuring the link of the hierarchical organization with the electronic structure of the mineralized phase in bone...
December 16, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27873509/dose-response-relationship-between-alanine-aminotransferase-levels-within-the-reference-interval-and-metabolic-syndrome-in-chinese-adults
#14
Peipei Wu, Qicai Chen, Lili Chen, Pengpeng Zhang, Juan Xiao, Xiaoxiao Chen, Meng Liu, Shumei Wang
PURPOSE: Elevation in serum alanine aminotransferase (ALT) levels is a biomarker for metabolic syndrome (MS); however, the relationship has not been fully investigated within the reference interval of ALT levels. Our objective was to explore the relationship between serum ALT levels within the reference interval and MS in Chinese adults. MATERIALS AND METHODS: This cross-sectional study included 16028 adults, who attended routine health check-ups at Shengli Oilfield Central Hospital from January 2006 to March 2012...
January 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27871828/pain-associated-with-urethral-catheterization-is-reduced-in-males-by-simultaneous-voiding-maneuver
#15
Kobi Stav, Yishai H Rappaport, Ilia Beberashvili, Amnon Zisman
OBJECTIVE: To assess whether urethral pain during male catheterization can be reduced if the patient is instructed to void during the insertion of the catheter. METHODS: 96 males (age 66±13) who were referred for multichannel Urodynamic study were prospectively randomized to 2 groups according to the catheter insertion technique: (1) patients were instructed to void during catheterization; (2) no guidance prior or during catheterization. Exclusion criteria were: use of analgesics within the previous 24 hours, active urinary tract infection, indwelling urethral catheter, pre-existing urethral pain, known urethral stricture or inability to cooperate with pain assessment due to mental disorders...
November 18, 2016: Urology
https://www.readbyqxmd.com/read/27870743/epidural-local-anesthetics-versus-opioid-based-analgesic-regimens-for-postoperative-gastrointestinal-paralysis-vomiting-and-pain-after-abdominal-surgery-a-cochrane-review
#16
Joanne Guay, Mina Nishimori, Sandra L Kopp
BACKGROUND: The aim of this review was to compare the effects of postoperative epidural analgesia with local anesthetics to postoperative systemic or epidural opioids in terms of return of gastrointestinal transit, postoperative pain control, postoperative vomiting, incidence of gastrointestinal anastomotic leak, hospital length of stay, and cost after abdominal surgery. METHODS: Trials were identified by computerized searches of the Cochrane Central Register of Controlled Trials (CENTRAL) (2014, Issue 12), Medical Literature Analysis and Retrieval System Online (MEDLINE) (from 1950 to December, 2014) and Excerpta Medica dataBASE (EMBASE) (from 1974 to December 2014) and by checking the reference lists of trials retained...
December 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27870589/results-of-a-prospective-study-evaluating-a-non-invasive-method-of-hemoglobin-adjustment-for-determining-the-diffusing-capacity-of-the-lung
#17
Karla E Foster, Rashmi D Sahay, Nanhua Zhang, William D Hardie
RATIONALE: Measurement of the lung diffusing capacity for carbon monoxide (DLCO) is significantly influenced by the pulmonary capillary blood volume. Consequently, measurements require adjustment for blood hemoglobin concentration (DLCOADJ) to allow meaningful clinical interpretation. Noninvasive point-of-care devices that measure hemoglobin transcutaneously provide immediate values for hemoglobin that may be useful in pulmonary function laboratories for determining DLCOADJ. OBJECTIVES: To test the hypothesis that DLCOADJ determinations obtained using a commerciallyavailable device for noninvasive, point-of-care measurement of blood hemoglobin concentrations are not importantly different from determinations obtained using hemoglobin concentrations measured conventionally on venous blood samples...
November 21, 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27869298/informant-questionnaire-on-cognitive-decline-in-the-elderly-iqcode-for-the-early-diagnosis-of-dementia-across-a-variety-of-healthcare-settings
#18
REVIEW
Jennifer K Harrison, David J Stott, Rupert McShane, Anna H Noel-Storr, Rhiannon S Swann-Price, Terry J Quinn
BACKGROUND: The Informant Questionnaire for Cognitive Decline in the Elderly (IQCODE) is a structured interview based on informant responses that is used to assess for possible dementia. IQCODE has been used for retrospective or contemporaneous assessment of cognitive decline. There is considerable interest in tests that may identify those at future risk of developing dementia. Assessing a population free of dementia for the prospective development of dementia is an approach often used in studies of dementia biomarkers...
November 21, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27867880/effect-of-curative-parathyroidectomy-on-insulin-resistance
#19
Rachel Putnam, Deba Prasad Dhibar, Shweta Varshney, Arunanshu Behera, B R Mittal, Anil Bhansali, Sudhaker D Rao, Sanjay Kumar Bhadada
BACKGROUND: Primary hyperparathyroidism (PHPT) is characterized by inappropriately elevated serum parathyroid hormone (PTH) level despite elevated serum calcium. Insulin resistant is the basic pathophysiology, behind the higher prevalence of diabetes mellitus in patients with PHPT. However, the improvement in insulin resistance (IR) after curative parathyroidectomy (CPTX) has not been established yet, as the study results are conflicting. MATERIALS AND METHODS: In this prospective interventional study, ten patients with mild PHPT (Group 1) and another ten patients with moderate to severe PHPT (Group 2) were undergone CPTX...
November 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27862099/identification-of-thermostabilizing-mutations-for-a-membrane-protein-whose-three-dimensional-structure-is-unknown
#20
Yuta Kajiwara, Satoshi Yasuda, Yuuki Takamuku, Takeshi Murata, Masahiro Kinoshita
We recently developed a physics-based method for identifying thermostabilizing mutations of a membrane protein. The method uses a free-energy function F where the importance of translational entropy of hydrocarbon groups within the lipid bilayer is emphasized. All of the possible mutations can rapidly be examined. The method was illustrated for the adenosine A2a receptor (A2a R) whose three-dimensional (3D) structure experimentally determined was utilized as the wild-type structure. Nine single mutations and a double mutation predicted to be stabilizing or destabilizing were checked by referring to the experimental results: The success rate was remarkably high...
November 14, 2016: Journal of Computational Chemistry
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