keyword
MENU ▼
Read by QxMD icon Read
search

recruit

keyword
https://www.readbyqxmd.com/read/28549335/microstructural-alterations-of-white-matter-in-juvenile-myoclonic-epilepsy
#1
Jinnan Gong, Xuebin Chang, Sisi Jiang, Benjamin Klugah-Brown, Song Tan, Dezhong Yao, Cheng Luo
Juvenile myoclonic epilepsy (JME) is a common type of idiopathic generalized epilepsy that is characterized by myoclonic jerks of the upper limbs and generalized tonic-clonic seizures. Frontal cognitive dysfunctions and abnormal coupling of the thalamocortical system have been found in neuropsychological and neuroimaging studies. This study intended to explore white matter (WM) measurement changes in JME using MRI. Twenty-six patients with JME and 25 healthy controls (HC) were recruited for the acquisition of diffusion MRI and structural MRI data...
April 4, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28549317/frontal-and-subcortical-grey-matter-reductions-in-ptsd
#2
Daniel C M O'Doherty, Ashleigh Tickell, Will Ryder, Charles Chan, Daniel F Hermens, Maxwell R Bennett, Jim Lagopoulos
Post-traumatic stress disorder (PTSD) is characterised by a range of debilitating psychological, physical and cognitive symptoms. PTSD has been associated with grey matter atrophy in limbic and frontal cortical brain regions. However, previous studies have reported heterogeneous findings, with grey matter changes observed beyond limbic/frontal areas. Seventy-five adults were recruited from the community, 25 diagnosed with PTSD along with 25 healthy and 25 trauma exposed age and gender matched controls. Participants underwent clinical assessment and magnetic resonance imaging...
May 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28549183/pain-assessment-recommendations-for-women-made-by-women-a-mixed-methods-study
#3
Geoff P Bostick, Bruce D Dick, Mary Wood, Barbara Luckhurst, Julie Tschofen, Timothy W Wideman
Objective.:  To quantitatively describe women's priorities for pain assessment and qualitatively explain unique features of women's pain experiences. Design.:  Mixed-methods study that included a three-round Delphi study followed by in-depth interviews. Setting. : Clinical research study. Participants.:  Twenty-three women with chronic pain recruited from three women's pain treatment facilities and one interdisciplinary chronic pain clinic...
May 26, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28549179/relationships-between-smoking-behaviors-and-cotinine-levels-among-two-american-indian-populations-with-distinct-smoking-patterns
#4
Julie-Anne Tanner, Jeffrey A Henderson, Dedra Buchwald, Barbara V Howard, Patricia Nez Henderson, Rachel F Tyndale
Introduction: Smoking prevalence, cigarettes per day (CPD), and lung cancer incidence differ between Northern Plains (NP) and Southwestern (SW) American Indian populations. We used cotinine as a biomarker of tobacco smoke exposure to biochemically characterize NP and SW smokers and non-smokers, and to investigate factors associated with variation in tobacco exposure. Methods: American Indians (N=636) were recruited from two different tribal populations (NP and SW) as part of a study conducted as part of the Collaborative to Improve Native Cancer Outcomes P50 project...
May 26, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28549163/factors-influencing-the-academic-performance-of-children-with-sickle-cell-anaemia-in-ekiti-south-west-nigeria
#5
Oladele Simeon Olatunya, Oluwasola Julius Oke, Bankole Peter Kuti, Iyiade Adeseye Ajayi, Oyebanji Olajuyin, Olubunmi Omotosho-Olagoke, Adekunle Bamidele Taiwo, Opeyemi Ayodeji Faboya, Ayodeji Ajibola
Background: There is a paucity of information on factors that influence the school performance of children with sickle cell anaemia (SCA) in Nigeria, despite her huge burden of the disease. Methods: In total, 101 children with SCA were recruited at a paediatric clinic in Nigeria. Their socio-demographic-matched classmates were the controls. Academic performance and cognitive functioning were obtained from school reports and Ziler's Draw-a-Person Test, respectively...
May 26, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28549161/cigarette-smoking-cessation-intervention-for-buprenorphine-treatment-patients
#6
Sharon M Hall, Gary Humfleet, James Gasper, Kevin L Delucchi, David Hersh, Joseph Guydish
Introduction: Patients receiving Medication Assisted Therapy (MAT) for opioid use disorder have high cigarette smoking rates. Cigarette smoking interventions have had limited success. We evaluated an intervention to increase cigarette abstinence rates in patients receiving buprenorphine-assisted therapy. Methods: Cigarette smokers (N=175; 78% male; 69% Caucasian; 20% Hispanic), recruited from a buprenorphine clinic were randomly assigned to either an extended innovative system intervention (E-ISI) or to Standard Treatment Control (STC)...
May 26, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28549156/early-subjective-sensory-experiences-with-cigalike-e-cigarettes-among-african-american-menthol-smokers-a-qualitative-study
#7
Sabrina L Smiley, Teresa DeAtley, Leslie F Rubin, Emily Harvey, Elexis C Kierstead, Monica Webb Hooper, Raymond S Niaura, David B Abrams, Jennifer L Pearson
Introduction: Despite smoker interest in e-cigarettes as a harm reduction or cessation aid, many smokers prematurely discontinue vaping after trying a product. This study explored the role of early subjective sensory experience in vaping persistence and desistence. Methods: African American menthol cigarette smokers aged ≥18 years (n=15; M=54.1 years; SD=8.2), motivated to quit smoking, and interested in trying e-cigarettes were recruited in Washington, D.C. Participants were followed for three weeks and provided menthol cigalike e-cigarettes after week one...
May 26, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28549131/a-novel-cortical-target-to-enhance-hand-motor-output-in-humans-with-spinal-cord-injury
#8
Jinyi Long, Paolo Federico, Monica A Perez
A main goal of rehabilitation strategies in humans with spinal cord injury is to strengthen transmission in spared neural networks. Although neuromodulatory strategies have targeted different sites within the central nervous system to restore motor function following spinal cord injury, the role of cortical targets remain poorly understood. Here, we use 180 pairs of transcranial magnetic stimulation for ∼30 min over the hand representation of the motor cortex at an interstimulus interval mimicking the rhythmicity of descending late indirect (I) waves in corticospinal neurons (4...
June 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28549080/life-history-traits-influence-the-strength-of-distance-and-density-dependence-at-different-life-stages-of-two-amazonian-palms
#9
Juanita Choo, Cecilia Carasco, Patricia Alvarez-Loayza, Beryl B Simpson, Evan P Economo
Background and Aims: Natural enemies are known to be important in regulating plant populations and contributing to species coexistence (Janzen-Connell effects). The strength of Janzen-Connell effects (both distance- and density-effects) varies across species, but the life history traits that may mediate such a variation are not well understood. This study examined Janzen-Connell effects across the life stages (seed through adult stages) of two sympatric palm species with distinct phenologies and shade tolerances, two traits that may mediate the strength and timing of Janzen-Connell effects...
May 26, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28549063/food-addiction-and-obesity-unnecessary-medicalization-of-hedonic-overeating
#10
REVIEW
Graham Finlayson
The concept of addiction is loaded with connotations and is often used for its political as much as its medical utility. The scientific case for 'food addiction' as a clinical phenotype currently rests on its association with generic diagnostic criteria for substance-related disorders being applied to everyday foods and eating-related problems. This has fused the concept of obesity with addiction regardless of whether it fits the definition. The hedonic, or reward, system can account for the ingestion of foods and drugs, confirming that they share neural substrates that differentiate liking and wanting...
May 26, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28549059/elimination-diet-and-the-development-of-multiple-tree-nut-allergies
#11
Arnon Elizur, Jennifer B Bollyky, Whitney M Block
BACKGROUNDDespite its high prevalence, relatively little is known about the characteristics of patients with multiple tree-nuts allergies.METHODSPatients (n=60, aged 4-15 years), recruited for a multiple food (tree-nuts, peanut, milk, egg, soy, sesame and wheat) oral immunotherapy (OIT) study, filled a questionnaire on their initial allergy evaluation. Medical records were reviewed. At OIT enrollment (median interval, 7.5 years), patients underwent oral food challenges (OFC) to foods still eliminated.RESULTSThere was significantly less evidence for eliminating tree-nuts compared to other foods, as reflected by lower rate of acute reaction to the offending food, either as the trigger for initial allergy evaluation (5...
May 26, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28548999/does-modic-change-progress-with-age
#12
Kiyoshi Tarukado, Teruaki Ono, Osamu Tono, Hiroki Tanaka, Ko Ikuta, Katsumi Harimaya, Toshio Doi
STUDY DESIGN: Cross-sectional imaging study. OBJECTIVE: The aim of this study was to clarify the trend in the generation distinctions about the prevalence of Modic change (MC) including elderly patients. SUMMARY OF BACKGROUND DATA: MC has been discussed regarding its clinical significance, relationship with low back pain, suitable treatments, prevalence, and natural history. However, previous reports have focused on younger subjects, with few studies conducted in elderly patients...
May 25, 2017: Spine
https://www.readbyqxmd.com/read/28548976/effect-of-prior-injury-on-changes-to-biceps-femoris-architecture-across-an-afl-season
#13
Ryan G Timmins, Matthew N Bourne, Jack T Hickey, Nirav Maniar, Paul J Tofari, Morgan D Williams, David A Opar
PURPOSE: To assess in-season alterations of biceps femoris long head (BFlh) fascicle length in elite Australian footballers with and without a history of HSI. METHODS: Thirty elite Australian football players were recruited. Twelve had a history of unilateral HSI. Eighteen had no HSI history. All had their BFlh architecture assessed at approximately monthly intervals, six times across a competitive season. RESULTS: The previously injured limb's BFlh fascicles increased from the start of the season and peaked at week 5...
May 25, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28548935/hdac4-stimulates-mrtf-a-expression-and-drives-fibrogenesis-in-hepatic-stellate-cells-by-targeting-mir-206
#14
Xinrui Han, Chenzhi Hao, Luyang Li, Jianfei Li, Mingming Fang, Yuanlin Zheng, Jun Lu, Ping Li, Yong Xu
Activation of hepatic stellate cells (HSCs) is a hallmark event during liver fibrogenesis. We have previously shown that the transcriptional modulator MRTF-A contributes to liver fibrosis by programming epigenetic activation of HSCs. In the present study we investigated the mechanism whereby MRTF-A expression is regulated in this process. We report here that MRTF-A protein levels, but not mRNA levels, were up-regulated in vivo in the livers of mice induced to develop hepatic fibrosis. Pro-fibrogenic stimuli (TGF-β and PDGF-BB) also activated MRTF-A expression post-transcriptionally in vitro in cultured HSCs...
May 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28548902/er-mitochondria-signaling-regulates-autophagy
#15
Patricia Gomez-Suaga, Sebastien Paillusson, Christopher C J Miller
The endoplasmic reticulum (ER) and mitochondria form tight functional contacts that regulate a number of key cellular processes. The formation of these contacts involves "tethering proteins" that function to recruit regions of ER to mitochondria. The integral ER protein VAPB (VAMP associated protein B and C) binds to the outer mitochondrial membrane protein, RMDN3/PTPIP51 (regulator of microtubule dynamics 3) to form one such set of tethers. Recently, we showed that the VAPB-RMDN3 tethers regulate macroautophagy/autophagy...
May 26, 2017: Autophagy
https://www.readbyqxmd.com/read/28548884/patient-centered-perspectives-and-understanding-of-peri-implantitis
#16
Angel Insua, Alberto Monje, Hom-Lay Wang, Marita Inglehart
BACKGROUND: Daily-basis patients have uncertain understanding about dental implant therapy and its complications. Therefore, an assessment of the level of knowledge, awareness and attitudes on peri-implantitis, evaluation of information provided by the dentist/specialist that performed the treatment and assessment of perceptions, level of satisfaction and impact in the quality of life of the patients were carried out. MATERIAL AND METHODS: Patients with implant therapy and currently undergoing peri-implant implant maintenance therapy were recruited...
May 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28548879/ras-and-rho-gtpase-regulation-of-pol-ii-transcription-a-shortcut-model-revisited
#17
Zhi-Liang Zheng
Transcriptional control is critical in relaying signals mediated by Ras and Rho family small GTPases to effect gene expression. In the classical model, signaling components such as MAP kinase target sequence-specific transcription factors, which in turn recruit RNA polymerase (Pol) II holoenzyme to the promoter and activate transcription. Findings in recent years have led to the proposal of a shortcut model in which the mediator components of the Pol II holoenzyme are regulated by signaling pathways. A very recent finding shows that an evolutionarily conserved Rho GTPase signaling pathway can directly modulate the Pol II C-terminal domain (CTD) phosphorylation by inhibiting the CTD phosphatase in yeast and Arabidopsis...
May 26, 2017: Transcription
https://www.readbyqxmd.com/read/28548651/foetal-haemoglobin-blood-transfusion-and-retinopathy-of-prematurity-in-very-preterm-infants-a-pilot-prospective-cohort-study
#18
C J Stutchfield, A Jain, D Odd, C Williams, R Markham
PurposeTo identify if there is an association between foetal haemoglobin (HbF) concentration and retinopathy of prematurity (ROP) in very preterm infants.Patients and methodsProspective cohort study. Infants born <32 weeks' gestational age or <1501 g in two tertiary neonatal units between January 2012 and May 2013 (n=42) were enrolled. HbF and adult haemoglobin (HbA) concentrations were measured using high-pressure liquid chromatography from blood samples sent as part of routine neonatal care once routinely requested laboratory tests had been performed...
May 26, 2017: Eye
https://www.readbyqxmd.com/read/28548649/aqueous-humor-endothelin-1-and-total-retinal-blood-flow-in-patients-with-non-proliferative-diabetic-retinopathy
#19
L-A Khuu, F Tayyari, J M Sivak, J G Flanagan, S Singer, M H Brent, D Huang, O Tan, C Hudson
PurposeThe purpose of this study was to determine the association between aqueous ET-1 levels and total retinal blood flow (TRBF) in patients with non-insulin-dependent type 2 diabetes mellitus (T2DM) and early non-proliferative diabetic retinopathy (NPDR).Patients and methodsA total of 15 age-matched controls and 15 T2DM patients with NPDR were recruited into the study. Aqueous humor (~80-120 μl) was collected before cataract surgery to measure the levels of ET-1 using suspension multiplex array technology...
May 26, 2017: Eye
https://www.readbyqxmd.com/read/28548619/stages-of-change-model-has-limited-value-in-explaining-the-change-in-use-of-cannabis-among-adolescent-participants-in-an-efficacious-motivational-interviewing-intervention
#20
Hans B Dupont, Math J J M Candel, Paul Lemmens, Charles D Kaplan, Dike van de Mheen, Nanne K De Vries
Previously, a Dutch randomized controlled trial evaluating an intervention aimed at changing adolescents' cannabis use, called Moti-4, has shown its efficacy. A secondary analysis of the Moti-4 data investigated the process of change specified by the Stage of Change (SOC) model in cannabis use during the trial. Seventy-one Moti-4 participants and 60 controls were recruited for the study with a pre-test, post-test (T1), and six-month follow-up (T2). All participants showed signs of problematic cannabis use. No contribution of the Moti-4 intervention to a change in SOC between T1 and T2 was found...
May 26, 2017: Journal of Psychoactive Drugs
keyword
keyword
90542
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"