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Cerebral oxigenation

Richard N Gates, Brian A Palafox, Beth Parker
Neonatal arch reconstructions present a challenge for myocardial protection. We report our results for eight patients treated with intermittent cold all blood retrograde cardioplegia during arch reconstruction using continuous selective normothermic cerebral perfusion. Over a 10-month period eight consecutive neonates underwent complex arch reconstruction. Mean age was 8.4 days (range 2-23); weight 3.1 kg (range 2.7-3.8). Diagnosis was hypoplastic left heart syndrome (5), interrupted aortic arch/ventriculoseptal defect (2), and complex AP window (1)...
September 2008: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Zoltán Nagy, László Simon, Zoltán Bori
Permanent or temporary disruption of cerebral blood flow rapidly depletes brain regions of their limited energy reserves (glycogen, glucose, oxygen, ATP) leading to an energy crisis. Tissue damage occurs due to the energy crisis. The central part of the damage, the ischaemic "core" region is surrounded by zones of the shell-like penumbra. Necrotic, as well as apoptotic cell death could be identified in the penumbra. Going away from the ischaemic core different neurochemical processes are occurring by space and time...
March 20, 2002: Ideggyógyászati Szemle
S B Daniiarov, E M Vilenskaia
The paper presents the results of the comparative study of the EEG at alpine altitudes (Tuya -- Ashu pass, 3200 m) and at low altitudes (City of Frunze, 760 m above the sea level). The dynamics of EEG changes at different stages of adaptation to hypoxia is also traced. The obtained data show that the alpine hypoxia produces a considerable intensification of the excitation processes in the cerebral cortex. Different sensitivity to the oxigen shortage has been found in the frontal-temporal parts of the right and the left hemispheres...
March 1980: Zhurnal Vyssheĭ Nervnoĭ Deiatelnosti Imeni I P Pavlova
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