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https://www.readbyqxmd.com/read/28803066/a-novel-ripk1-inhibitor-that-prevents-retinal-degeneration-in-a-rat-glaucoma-model
#1
Yun-Ju Do, Jee-Won Sul, Ki-Hong Jang, Nam Sook Kang, Young-Hoon Kim, Young-Gwan Kim, Eunhee Kim
In glaucoma, retinal ganglion cells (RGCs) are exposed to ischemic stress with elevation of the intraocular pressure and are subsequently lost. Necroptosis, a type of regulated necrosis, is known to play a pivotal role in this loss. We observed that receptor-interacting protein kinase 1 (RIPK1), the key player of necroptosis, was activated by diverse ischemic stresses, including TCZ, chemical hypoxia (CH), and oxygen glucose deprivation (OGD). In this study, we introduce a RIPK1-inhibitory compound (RIC) with a novel scaffold...
August 9, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28792067/the-role-of-sleep-in-the-relation-between-young-children-s-mobile-media-use-and-effortful-control
#2
Amy I Nathanson, Ine Beyens
We explored the relations among young children's mobile media use, sleep, and a form of self-regulation, temperamental effortful control (EC), among a national sample of 402 mothers who completed an online survey. We found that the relation between mobile media use and EC was moderated by children's sleep time. Tablet use was negatively related to EC only among children who slept less at night (40% of our sample). However, hand-held game player use was positively related to EC among children who slept longer at night (60% of our sample)...
August 9, 2017: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/28789628/patellar-tendinopathy-in-young-elite-soccer-clinical-and-sonographical-analysis-of-a-german-elite-soccer-academy
#3
Gerrit Bode, Thorsten Hammer, N Karvouniaris, M J Feucht, L Konstantinidis, N P Südkamp, A Hirschmüller
BACKGROUND: The prevalence of patellar tendinopathy is elevated in elite soccer compared to less explosive sports. While the burden of training hours and load is comparably high in youth elite players (age < 23 years), little is known about the prevalence of patellar tendinopathy at this age. There is only little data available on the influence of age, the amount of training, the position on the field, as well as muscular strength, range of motion, or sonographical findings in this age group...
August 8, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28782096/the-prevention-of-musculoskeletal-injuries-in-volleyball-the-systematic-development-of-an-intervention-and-its-feasibility
#4
Vincent Gouttebarge, Marije van Sluis, Evert Verhagen, Johannes Zwerver
BACKGROUND: A scientific research project has started in the Netherlands with the aim of developing and implementing an evidence-based intervention to prevent the occurrence of musculoskeletal injuries among young and adult recreational volleyball players. This article describes (i) the systematic development of the intervention; and (ii) the assessment of its feasibility in terms of relevancy, suitability and usability. SYSTEMATIC DEVELOPMENT OF THE INTERVENTION: The development of the intervention was based on the Intervention Mapping structured and systematic process...
December 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/28774797/mesenchymal-stroma-role-in-osteosarcoma-progression
#5
Margherita Cortini, Sofia Avnet, Nicola Baldini
The initiation and progression of malignant tumors are supported by their microenvironment: cancer cells per se cannot explain growth and formation of the primary or metastasis, and a combination of proliferating tumor cells, cancer stem cells, immune cells mesenchymal stromal cells and/or cancer-associated fibroblasts all contribute to the tumor bulk. The interaction between these multiple players, under different microenvironmental conditions of biochemical and physical stimuli (i.e. oxygen tension, pH, matrix mechanics), regulates the production and biological activity of several soluble factors, extracellular matrix components, and extracellular vesicles that are needed for growth, maintenance, chemoresistance and metastatization of cancer...
July 31, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28774252/acute-traumatic-swan-neck-deformity-a-case-report-of-the-oblique-retinacular-ligament-lesion
#6
Giuseppe Checcucci, Marco Biondi, Marina Faccio, Piergiuseppe Zampetti, Mariarosaria Galeano, Massimo Ceruso
Swan neck deformity (SND) can be the manifestation of an acute trauma. We present a case report of a young basketball player with an acute traumatic SND determined by the single ulnar oblique retinacular ligament rupture. The patient caught a ball directly upon the tip of his right's hand middle finger into extension. He immediately presented a SND with impossibility to actively flex the proximal interphalangeal joint (PIPJ), while preserving active flexion and extension of the distal interphalangeal joint (DIPJ)...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28764148/the-anthropometric-correlates-for-the-physiological-demand-of-strength-and-flexibility-a-study-in-young-indian-field-hockey-players
#7
Hanjabam Barun Sharma, Jyotsna Kailashiya
INTRODUCTION: Optimal strength and flexibility are essential for performance enhancement and injury prevention in hockey, and anthropometry is known to influence these parameters. AIM: To find anthropometric correlates for strength and flexibility score in young Indian field hockey players. MATERIALS AND METHODS: Thirteen female and 19 male subjects volunteered for the study. Selected anthropometric variables: lengths, breadths, girths and body composition; strength and sit and reach score were measured for each subject...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28761702/static-stretching-does-not-enhance-recovery-in-elite-youth-soccer-players
#8
Sam Pooley, Owen Spendiff, Matt Allen, Hannah J Moir
BACKGROUND: Static stretching (SS) is a recovery intervention used for the reduction of muscle soreness postexercise. The effects of SS on elite young footballers have received little attention, and therefore the aim of this study was to assess the effects of SS on muscle recovery following competitive soccer matches in elite young footballers. METHODS: Ten male participants (16±1 years) were recruited from an English Premier League professional soccer academy...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/28759539/reliability-characteristics-and-applicability-of-a-repeated-sprint-ability-test-in-male-young-soccer-players
#9
Carlo Castagna, Lorenzo Francini, Peter Krustrup, Juliano Fenarnandes-da-Silva, Susana C A Póvoas, Andrea Bernardini, Stefano D'Ottavio
The aim of this study was to examine the usefulness and reliability characteristics of a repeated sprint ability test considering 5 line sprints of 30-m interspersed with 30-s of active recovery in non-elite outfield young male soccer players. Twenty-six (age 14.9±1.2 years, height 1.72±0.12 cm, body mass 62.2±5.1 kg) players were tested 48 hours and 7 days apart for 5x30-m performance over 5 trials (T1-T5). Short- (T1-T2) and long-term reliability (T1-T3-T4-T5) were assessed with Intraclass Correlation Coefficient (ICC) and with typical error for measurement (TEM)...
July 28, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28759536/ranking-prediction-model-using-the-competition-record-of-ladies-professional-golf-association-players
#10
Jin Seok Chae, Jin Park, Wi-Young So
The purpose of this study was to suggest a ranking prediction model using the competition record of the Ladies Professional Golf Association (LPGA) players. The top 100 players on the tour money list from the 2013-2016 US Open were analyzed in this model. Stepwise regression analysis was conducted to examine the effect of performance and independent variables (i.e., driving accuracy, green in regulation, putts per round, driving distance, percentage of sand saves, par-3 average, par-4 average, par-5 average, birdies average, and eagle average) on dependent variables (i...
July 28, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28751531/the-preventive-effect-of-a-soccer-specific-ankle-brace-on-acute-lateral-ankle-sprains-in-girls-amateur-soccer-players-study-protocol-of-a-cluster-randomised-controlled-trial
#11
Karin Thijs, Bionka Huisstede, Edwin Goedhart, Frank Backx
BACKGROUND: Acute lateral ankle sprains are the single most often diagnosed injury in female soccer players and often result in an inability to play. This highlights the need for effective prevention strategies. Proprioceptive training and/or the use of an external support to decrease inversion of the ankle joint can prevent or reduce the number of acute lateral ankle sprains. The effectiveness of a soccer-specific ankle brace in reducing first-time and recurrent acute lateral ankle sprains has never been investigated in girl soccer players...
July 27, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28746058/rapid-number-naming-and-quantitative-eye-movements-may-reflect-contact-sport-exposure-in-a-collegiate-ice-hockey-cohort
#12
Lisena Hasanaj, Sujata P Thawani, Nikki Webb, Julia D Drattell, Liliana Serrano, Rachel C Nolan, Jenelle Raynowska, Todd E Hudson, John-Ross Rizzo, Weiwei Dai, Bryan McComb, Judith D Goldberg, Janet C Rucker, Steven L Galetta, Laura J Balcer
BACKGROUND: The King-Devick (K-D) test of rapid number naming is a reliable visual performance measure that is a sensitive sideline indicator of concussion when time scores worsen (lengthen) from preseason baseline. Within cohorts of youth athletes <18 years old, baseline K-D times become faster with increasing age. We determined the relation of rapid number-naming time scores on the K-D test to electronic measurements of saccade performance during preseason baseline assessments in a collegiate ice hockey team cohort...
July 25, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28742607/pitch-counts-in-youth-baseball-and-softball-a-historical-review
#13
Brian T Feeley, Jessica Schisel, Julie Agel
OBJECTIVE: Pitching injuries are getting increased attention in the mass media. Many references are made to pitch counts and the role they play in injury prevention. The original purpose of regulating the pitch count in youth baseball was to reduce injury and fatigue to pitchers. This article reviews the history and development of the pitch count limit in baseball, the effect it has had on injury, and the evidence regarding injury rates on softball windmill pitching. DATA SOURCE: Literature search through PubMed, mass media, and organizational Web sites through June 2015...
July 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28724273/effects-of-inhaled-salbutamol-on-sport-specific-fitness-of-non-asthmatic-football-players
#14
Farzin Halabchi, Mahdi Abarashi, Mohammad Ali Mansournia, Tohid Seifbarghi
In this article, we investigated the effectiveness of inhaled salbutamol withtherapeutic dose on the sport-specific performance of non-asthmatic young football players. In a double-blinded, randomised placebo controlled trial with 2-treatment, 2-period crossover design, twenty participants who were non-asthmatic junior professional football players were randomly allocated to two groups. Fifteen minutes before sport-specific fitness testing, each group randomly received 2 inhalations (200 micrograms) of salbutamol or placebo, respectively...
May 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28723818/somatotype-and-body-composition-in-young-soccer-players-according-to-the-playing-position-and-sport-success
#15
Víctor Cárdenas-Fernández, José Luis Chinchilla-Minguet, Alfonso Castillo-Rodríguez
Soccer players undergo an evolution in their body composition throughout the growth and passage through the different base stages, that is, childhood, puberty and adolescence. The aim of this study was to analyze the morphology and body composition of U14, U16, and U19 soccer players, taking into account in addition, their sport success endorsed through the regularity participation and their relation with the different playing positions occupied during competition (goalkeeper, external defender, central defender, midfielder and forward/extreme)...
July 17, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28713471/assessment-of-specificity-of-the-badcamp-agility-test-for-badminton-players
#16
Luiz de França Bahia Loureiro, Mário Oliveira Costa Dias, Felipe Couto Cremasco, Maicon Guimarães da Silva, Paulo Barbosa de Freitas
The Badcamp agility test was created to evaluate agility of badminton players. The Badcamp is a valid and reliable test, however, a doubt about the need for the use of this test exists as simpler tests could provide similar information about agility in badminton players. Thus, the aim of this study was to examine the specificity of the Badcamp, comparing the performance of badminton players and athletes from other sports in the Badcamp and the shuttle run agility test (SRAT). Sixty-four young male and female athletes aged between 14 and 16 years participated in the study...
June 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28712981/judo-practice-in-early-age-promotes-high-level-of-bone-mass-acquisition-of-growing-boys-skeleton
#17
Kawther Missawi, Mohamed Zouch, Hamada Chaari, Yosra Chakroun, Zouhair Tabka, Elyès Bouajina
The current study aimed to exhibit effects of judo training for at least 2 yr on bone mass parameters in growing boys. Our population was composed of one hundred and thirty boys in tanner stage 1 and aged 10.52 ± 0.86 yr. Eleven judo players were therefore, excluded from the study because they do not have participate regularly to the judo training sessions during the last 2 yr. The resting sample was divided into two groups: 50 judo players (JU group) and 69 controls (C group). Bone mineral density (BMD), bone mineral content (BMC), and bone area (BA) were evaluated by using dual-photon X-ray absorptiometry on weight-bearing sites: the whole body, lumbar spine (L2-L4), legs, femoral necks and hips and on the non-weight bearing sites: arms and radiuses...
July 13, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28702736/changes-in-the-axon-terminals-of-primary-afferents-from-a-single-vibrissa-in-the-rat-trigeminal-nuclei-after-active-touch-deprivation-or-exposure-to-an-enriched-environment
#18
Julia Fernández-Montoya, Yasmina B Martin, Pilar Negredo, Carlos Avendaño
Lasting modifications of sensory input induce structural and functional changes in the brain, but the involvement of primary sensory neurons in this plasticity has been practically ignored. Here, we examine qualitatively and quantitatively the central axonal terminations of a population of trigeminal ganglion neurons, whose peripheral axons innervate a single mystacial vibrissa. Vibrissa follicles are heavily innervated by myelinated and unmyelinated fibers that exit the follicle mainly through a single deep vibrissal nerve...
July 12, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28699924/position-specific-acceleration-and-deceleration-profiles-in-elite-youth-and-senior-soccer-players
#19
Jeppe F Vigh-Larsen, Ulrik Dalgas, Thomas B Andersen
The purpose of the study was to characterize and compare the position specific activity profiles of young and senior elite soccer players with special emphasis put on accelerations and decelerations. Eight professional senior matches were tracked using the ZXY tracking system and analyzed for number of accelerations and decelerations and running distances within different speed zones. Likewise, four U19- and five U17 matches were analyzed for comparison between youth and senior players. In senior players the total distance (TD) was 10776±107 m with 668±28 and 143±10 m being high-intensity running (HIR) and sprinting, respectively...
April 4, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28680897/high-prevalence-of-nontraumatic-shoulder-pain-in-a-regional-sample-of-female-high-school-volleyball-athletes
#20
Kayt E Frisch, Jacob Clark, Chad Hanson, Chris Fagerness, Adam Conway, Lindsay Hoogendoorn
BACKGROUND: Shoulder pain is becoming increasingly problematic in young players as volleyball gains popularity. Associations between repetitive motion and pain and overuse injury have been observed in other overhand sports (most notably baseball). Studies of adult athletes suggest that there is a shoulder pain and overuse problem present in volleyball players, but minimal research has been done to establish rates and causes in juvenile participants. PURPOSE: To establish rates of shoulder pain, regardless of whether it resulted in a loss of playing time, in female high school volleyball players...
June 2017: Orthopaedic Journal of Sports Medicine
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