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https://www.readbyqxmd.com/read/27911820/map4-regulated-dynein-dependent-trafficking-of-btn3a1-controls-the-tbk1-irf3-signaling-axis
#1
Minji Seo, Seong-Ok Lee, Ji-Hoon Kim, Yujin Hong, Seongchan Kim, Yeumin Kim, Dal-Hee Min, Young-Yun Kong, Jinwook Shin, Kwangseog Ahn
The innate immune system detects viral nucleic acids and induces type I interferon (IFN) responses. The RNA- and DNA-sensing pathways converge on the protein kinase TANK-binding kinase 1 (TBK1) and the transcription factor IFN-regulatory factor 3 (IRF3). Activation of the IFN signaling pathway is known to trigger the redistribution of key signaling molecules to punctate perinuclear structures, but the mediators of this spatiotemporal regulation have yet to be defined. Here we identify butyrophilin 3A1 (BTN3A1) as a positive regulator of nucleic acid-mediated type I IFN signaling...
November 22, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27905867/effects-of-lawn-tennis-association-mini-tennis-as-task-constraints-on-children-s-match-play-characteristics
#2
Anna Fitzpatrick, Keith Davids, Joseph Antony Stone
The Lawn Tennis Association's mini tennis (MT) is a modified version of tennis consisting of progressive stages; however, there have been few attempts to evaluate how MT might shape performance behaviours. Here, we examine effects of playing MT on the emergence of children's match-play behaviours in 48 junior tennis players. Performance in 1010 match-play points were filmed and coded across 4 tennis stages (MT Red, MT Orange, MT Green and Full Ball), using a notational analysis system. Recorded performance variables included rally length, first serve percentage and shot type, for the purpose of analysing inter-stage comparisons...
December 1, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27900189/novel-coaching-cricket-bat-can-it-be-used-to-enhance-the-backlift-and-performance-of-junior-cricket-batsmen
#3
M Habib Noorbhai, Russell C Woolmer, Timothy D Noakes
BACKGROUND: In the current literature, it is questionable whether cricket bats in their current form and dimensions allow a young cricketer to hit the ball effectively. The aim of this study was to test the effectiveness of a novel coaching cricket bat among junior cricket batsmen with regard to enhancing performance and the direction of the backlift. METHODS: A cross-sectional research study with analytical research methods was employed, in which 2 groups (coached: n=12 and uncoached: n=35) of participants (ages 9-13) took part in a pilot and intervention study...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27900186/injury-incidence-in-a-premier-league-youth-soccer-academy-using-the-consensus-statement-a-prospective-cohort-study
#4
Andrew Renshaw, Peter C Goodwin
BACKGROUND: There is an established risk of injury to young athletes exposed to high training loads. Identifying and monitoring injury risk is essential to aid prevention. The aim of this study was to use the consensus statement to determine the incidence and pattern of injury in 1 English Premier League soccer academy during 1 season. METHODS: A prospective cohort study included 181 elite academy soccer players during the 2012-2013 season. Players were divided into 5 age groups between 9 and 18 years...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27893897/imaging-of-glial-cell-activation-and-white-matter-integrity-in-brains-of-active-and-recently-retired-national-football-league-players
#5
Jennifer M Coughlin, Yuchuan Wang, Il Minn, Nicholas Bienko, Emily B Ambinder, Xin Xu, Matthew E Peters, John W Dougherty, Melin Vranesic, Soo Min Koo, Hye-Hyun Ahn, Merton Lee, Chris Cottrell, Haris I Sair, Akira Sawa, Cynthia A Munro, Christopher J Nowinski, Robert F Dannals, Constantine G Lyketsos, Michael Kassiou, Gwenn Smith, Brian Caffo, Susumu Mori, Tomas R Guilarte, Martin G Pomper
Importance: Microglia, the resident immune cells of the central nervous system, play an important role in the brain's response to injury and neurodegenerative processes. It has been proposed that prolonged microglial activation occurs after single and repeated traumatic brain injury, possibly through sports-related concussive and subconcussive injuries. Limited in vivo brain imaging studies months to years after individuals experience a single moderate to severe traumatic brain injury suggest widespread persistent microglial activation, but there has been little study of persistent glial cell activity in brains of athletes with sports-related traumatic brain injury...
November 28, 2016: JAMA Neurology
https://www.readbyqxmd.com/read/27893475/leg-stiffness-in-female-soccer-players-inter-session-reliability-and-the-fatiguing-effects-of-soccer-specific-exercise
#6
Mark De Ste Croix, Jonathan Hughes, Rhodri S Lloyd, Jon L Oliver, Paul Read
Low levels of leg stiffness and reduced leg stiffness when fatigue is present compromise physical performance and increase injury risk. The purpose of this study was to (a) determine the reliability of leg stiffness measures obtained from contact mat data and (b) explore age-related differences in leg stiffness following exposure to a soccer-specific fatigue protocol in young female soccer players. 37 uninjured female youth soccer players divided into 3 sub-groups based on chronological age (U13, U15 and U17 year olds) volunteered to participate in the study...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27885394/sports-specific-differences-in-postsurgical-infections-after-arthroscopically-assisted-anterior-cruciate-ligament-reconstruction
#7
Werner Krutsch, Johannes Zellner, Florian Zeman, Michael Nerlich, Matthias Koch, Christian Pfeifer, Peter Angele
PURPOSE: Post-operative infection after arthroscopically assisted anterior cruciate ligament (ACL) reconstruction is a rare but severe complication, particularly for young and active patients. It is unclear whether the prevalence of knee infection is correlated with the type of sports or the level of performance. METHODS: From 2008 to 2012, the internal single-centre ACL registry of the FIFA Medical Centre of Excellence Regensburg was retrospectively screened for sex, age, time between isolated primary ACL rupture and surgery, surgical technique, rate of infection after ACL reconstruction and the type of sports practised...
November 24, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27870080/players-doctors-the-roles-should-be-very-clear
#8
Arthur L Caplan, Brendan Parent, Lee H Igel
Years ago, one of us had the opportunity to talk with a starting guard in the National Basketball Association about his health care. The player, then a rookie, did not have his own personal doctor. Instead, he received his health care from the team doctor. This athlete was very well paid and could have received care anywhere he wished in the area. But he came from a very poor neighborhood. Growing up, he said, he had no health care other than hearing and eye tests done at his school and maybe (he was not sure) vaccinations given by the school nurse...
November 2016: Hastings Center Report
https://www.readbyqxmd.com/read/27863793/plantar-pressure-asymmetry-and-risk-of-stress-injuries-in-the-foot-of-young-soccer-players
#9
Renato R Azevedo, Emmanuel S da Rocha, Pedro S Franco, Felipe P Carpes
BACKGROUND: Asymmetries in the magnitude of plantar pressure are considered a risk factor for stress fracture of the fifth metatarsal in soccer athletes. OBJECTIVE: To investigate the presence of plantar pressure asymmetries among young soccer athletes. DESIGN: Observational. SETTING: Laboratory. PARTICIPANTS: Thirty young adolescents divided into a soccer player group (n = 15) or a matched control group (n = 15)...
October 24, 2016: Physical Therapy in Sport
https://www.readbyqxmd.com/read/27852593/humeral-retrotorsion-and-glenohumeral-motion-in-youth-baseball-players-compared-with-age-matched-nonthrowing-athletes
#10
Elliot M Greenberg, J Todd R Lawrence, Alicia Fernandez-Fernandez, Philip McClure
BACKGROUND: Baseball players exhibit a more posteriorly oriented humeral head in their throwing arm. This is termed humeral retrotorsion (HRT) and likely represents a response to the stress of throwing. This adaptation is thought to occur while the athlete is skeletally immature, however currently there is limited research detailing how throwing activity in younger players influences the development of HRT. In addition, it is presently unclear how this changing osseous orientation may influence shoulder motion within young athletes...
November 16, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27847782/traumatic-pseudoaneurysm-related-to-calcified-nodules-of-cerebral-convexity-dura-mater-in-an-american-college-football-player
#11
Yoo Sung Jeon, Jong Gon Lee, Young Il Chun, Joon Cho, Woo Jin Choe
Repeated concussion is common among football players; however, these minor blunt head trauma rarely result in serious complications. We report a case of a young college football player who presented acute subdural hematoma, cerebral edema, and seizure due to pseudoaneurysm rupture. The pseudoaneurysm, located at the cortical branch of the middle cerebral artery, was speculated to be formed by dural calcification and adhesion with the underlying brain, possibly due to repeated concussions. Following successful excision of the pseudoaneurysm and control of brain swelling, the patient recovered without sequelae and was discharged after a short while...
September 2016: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/27837349/comparison-of-body-composition-and-nutrients-deficiencies-between-portuguese-rink-hockey-players
#12
Maria-Raquel G Silva, Hugo-Henrique Silva
: We evaluated dietary intake and body composition of child and adolescent rink-hockey players and controls. Seventy-two male rink-hockey players (38 children and 34 adolescents) and 79 male controls (43 children and 36 adolescents) were evaluated in order to collect training data, detailed dietary intake and body composition. Rink-hockey players presented significantly lower body fat (BF) and higher fat-free mass (FFM) than controls. Mean intakes of carbohydrate and protein were considered to be adequate, but mean intakes of fat were above the recommended levels in athletes...
November 12, 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27834570/evolution-of-game-s-demands-from-young-to-elite-players-in-men-s-volleyball
#13
Antonio García-de-Alcaraz Serrano, David Valadés, José M Palao
PURPOSE: The purpose of this study was to assess the evolution of the game's demands throughout players' development in men's volleyball. METHODS: A total of 150 sets and 6.671 rallies were analysed. The sample was composed of 30 sets each by under-14, under-16, under-19, national senior, and international senior teams (1.291, 1.318, 1.310, 1.372 and 1.380 rallies for each category, respectively). Sets included in the sample were stratified and then randomly selected...
November 11, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27826397/the-effect-of-precooling-on-exhaustive-performance-in-the-hot-environment
#14
Ahmad Azad, Mansour Mousavi, Ali Gorzi, Aghaali Ghasemnian
BACKGROUND: Pre-cooling is known to enhance exercise performance in soccer players. However, little information currently exists regarding precooling effects in Iranian young soccer players. OBJECTIVES: The aim of this study was to assess the effect of precooling (water immersion) on exhaustive performance in the heat ( temperature = 32 - 34°C, humidity = 50%). PATIENTS AND METHODS: Sixteen young male soccer players from the provincial competitive teams were divided into two equal groups and were randomly assigned to precooling (age = 16...
September 2016: Asian Journal of Sports Medicine
https://www.readbyqxmd.com/read/27823916/-deep-venous-thrombosis-of-the-upper-limb-in-a-violin-player-the-bow-syndrome
#15
H Sanson, V Gautier, A Stansal, D Sfeir, C Franceschi, P Priollet
BACKGROUND: Exercise-induced thrombosis is a rare cause of deep venous thrombosis (DVT) of the upper limb and usually affects young subjects without comorbid conditions. The diagnosis may be challenging. CASE REPORT: A 23-year-old female right-handed French teacher and amateur violin player presented with edema of the root of the right arm associated with erythrocyanosis of the extremity and collateral circulation of the shoulder. History taking revealed oral contraception and recent change in violin playing habits...
November 4, 2016: Journal des Maladies Vasculaires
https://www.readbyqxmd.com/read/27822128/epidemiology-and-location-of-rugby-injuries-treated-in-us-emergency-departments-from-2004-to-2013
#16
Vani Sabesan, Zachary Steffes, Daniel J Lombardo, Graysen R Petersen-Fitts, Toufic R Jildeh
Rugby participation in the US is increasing, and with its inclusion in the 2016 Summer Olympics, the increased participation rates are expected to continue. Naturally, as participation increases, so too do rugby-related injuries. The difference in injury patterns with regard to age and gender illustrates differences in how the game is being played. Understanding what accounts for these emerging injury patterns will help guide future injury prevention efforts. This study provides an update on injury rates for the growing population of rugby players in the US, especially young players...
2016: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/27819056/nuclear-respiratory-factor-1-and-endurance-exercise-promote-human-telomere-transcription
#17
Aurélie Diman, Joanna Boros, Florian Poulain, Julie Rodriguez, Marin Purnelle, Harikleia Episkopou, Luc Bertrand, Marc Francaux, Louise Deldicque, Anabelle Decottignies
DNA breaks activate the DNA damage response and, if left unrepaired, trigger cellular senescence. Telomeres are specialized nucleoprotein structures that protect chromosome ends from persistent DNA damage response activation. Whether protection can be enhanced to counteract the age-dependent decline in telomere integrity is a challenging question. Telomeric repeat-containing RNA (TERRA), which is transcribed from telomeres, emerged as important player in telomere integrity. However, how human telomere transcription is regulated is still largely unknown...
July 2016: Science Advances
https://www.readbyqxmd.com/read/27806013/the-effect-of-high-speed-strength-training-on-physical-performance-in-young-soccer-players-of-different-ages
#18
David Rodriguez-Rosell, Felipe Franco-Márquez, Ricardo Mora-Custodio, Juan José González-Badillo
The aim of the present study was to compare the effectiveness of low-load, low-volume weight training combined with plyometrics on strength, sprint and jump performance in soccer players of different ages. Eighty-six soccer players from the same academy were categorized into 3 groups by age (under 13 year, U13, n = 30; under 15, U15, n = 28; under 17, U17, n = 28) and then randomly assigned into two subgroups: a strength training group (STG) and a control group (CG). The strength training program was performed twice a week for 6 weeks and consisted of full squats (load: 45-60% 1RM; volume: 3 set of 8-4 repetitions), jumps and straight line sprint exercises...
October 28, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27806003/fitness-profiles-of-elite-adolescent-irish-rugby-union-players
#19
Daniel J Wood, Garrett Coughlan, Eamonn Delahunt
Rugby unions throughout the world are implementing player development models in order to prepare young players to meet the demands of professional rugby union. An example of this is the Irish Rugby Football Union Long Term Player Development model. The purpose of the present study was to provide normative data relating to the physical fitness of elite adolescent Irish rugby union players and determine the differences in the physical capacities between players in the forward and back units, as well as providing descriptive data for the position categorizations within these units for this unique population...
October 27, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27797395/continuity-change-and-complexity-in-the-performance-of-masculinity-among-elite-young-footballers-in-england
#20
Steven Roberts, Eric Anderson, Rory Magrath
Following recent research evidencing that young men are redefining the essential components of what it is to be a man, this paper draws on qualitative interviews with 22 elite-level, English Premier League academy level football (soccer) players to investigate their performances and understandings of masculinity in relation to decreasing homohysteria. Even in this gender-segregated, near-total institution, these working-class, non-educationally aspiring adolescents evidence an attenuated performance of 'maleness' and improved attitudinal disposition toward homosexuality...
October 31, 2016: British Journal of Sociology
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