Gishan Ratnayake, Michael Huo, Akash Mehta, Prabhakar Ramachandran, Mark B Pinkham, Phillip Law, Trevor Watkins, Sarah Olson, Bruce Hall, Simon Brown, Ryan Lusk, Catherine Jones, Eoin O'Mahoney, George McGill, Matthew C Foote
OBJECTIVES: To investigate the impact of adding 68Ga-DOTATATE PET/MRI to standard MRI for target volume delineation in Gamma Knife® stereotactic radiosurgery (GKSRS) for meningioma. METHODS: Seventeen patients with 18 lesions undergoing GKSRS for WHO grade 1 meningioma were enrolled in a prospective study. All patients underwent pre-treatment 68Ga-DOTATATE PET/MRI examination in addition to standard procedures. Five clinicians independently contoured the gross tumour volume (GTV) based on standard MRI (GTVMRI) and PET/MRI (GTVPET/MRI) on separate occasions...
January 23, 2024: British Journal of Radiology