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https://www.readbyqxmd.com/read/29151054/effect-of-ephedrine-and-phenylephrine-on-brain-oxygenation-and-microcirculation-in-anaesthetised-patients-with-cerebral-tumours-study-protocol-for-a-randomised-controlled-trial
#1
Klaus Ulrik Koch, Anna Tietze, Joel Aanerud, Gorm von Öettingen, Niels Juul, Jens Christian Hedemann Sørensen, Lone Nikolajsen, Leif Østergaard, Mads Rasmussen
INTRODUCTION: During brain tumour surgery, vasopressor drugs are commonly administered to increase mean arterial blood pressure with the aim of maintaining sufficient cerebral perfusion pressure. Studies of the commonly used vasopressors show that brain oxygen saturation is reduced after phenylephrine administration, but unaltered by ephedrine administration. These findings may be explained by different effects of phenylephrine and ephedrine on the cerebral microcirculation, in particular the capillary transit-time heterogeneity, which determines oxygen extraction efficacy...
November 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/29104741/lymph-node-imaging-in-initial-staging-of-prostate-cancer-an-overview-and-update
#2
REVIEW
Jessica G Zarzour, Sam Galgano, Jonathan McConathy, John V Thomas, Soroush Rais-Bahrami
Accurate nodal staging at the time of diagnosis of prostate cancer is crucial in determining a treatment plan for the patient. Pelvic lymph node dissection is the most reliable method, but is less than perfect and has increased morbidity. Cross sectional imaging with computed tomography (CT) and magnetic resonance imaging (MRI) are non-invasive tools that rely on morphologic characteristics such as shape and size of the lymph nodes. However, lymph nodes harboring metastatic disease may be normal sized and non-metastatic lymph nodes may be enlarged due to reactive hyperplasia...
October 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/29098376/e-edmund-kim-hyung-jun-im-dong-soo-lee-keon-wook-kang-atlas-and-anatomy-of-pet-mri-pet-ct-and-spect-ct-springer-international-publishing-switzerland-2016-isbn-978-3-319-28650-1
#3
Giuseppe Danilo Di Stasio, Luigi Mansi
No abstract text is available yet for this article.
November 2, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29073488/solid-pseudopapillary-tumor-of-the-pancreas-clinical-features-and-imaging-findings
#4
Dong-Li Li, Hong-Sheng Li, Yi-Kai Xu, Quan-Shi Wang, Rui-Ying Chen, Fang Zhou
This study aimed to report clinical features and CT, MRI, PET/CT findings of solid pseudopapillary tumor (SPT) of the pancreas. Thirty-four patients with pathologically proven SPT were retrospectively reviewed. Most patients were asymptomatic. SPTs in male patients mainly appeared as solid and near solid tumors. Mixed tumors and cystic tumors had larger size than solid and near solid tumors. Solid tumors and solid part of mixed tumors were T2 hyperintense and T1 hypointense and had progressive enhancement. Four tumors (80%) showed markedly even or uneven (18)F-FDG uptake...
October 13, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29072103/posterior-cortical-atrophy-of-a-suspected-non-alzheimer-type-a-case-report
#5
Mark T Wagner, Dana M Szeles, Blakely Mulder, Mimi Sohn, Aljoeson Walker
OBJECTIVE: A case of Posterior Cortical Atrophy syndrome of a suspected non-Alzheimer disease pathology type is presented to illustrate prospective diagnosis and course. METHOD: A 54-year-old woman with vague memory complaints underwent serial neuropsychological assessment, MRI, PET, and CSF screening; data are reviewed. RESULTS: While early diagnosis was confounded by multiple factors, classic visuospatial symptoms were later demonstrated using routine neuropsychological methods...
October 26, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29068109/firefly-luciferin-inspired-biocompatible-chemistry-for-protein-labeling-and-in-vivo-imaging
#6
Yuqi Wang, Ruibing An, Zhiliang Luo, Deju Ye
Biocompatible reactions have emerged as versatile tools to build various molecular imaging probes that hold great promise for the detection of biological processes in vitro and/or in vivo. In this minireview, we describe the recent advances in the development of a firefly luciferin-inspired biocompatible reaction between cyanobenzothiazole (CBT) and cysteine (Cys), and highlight its versatility to label proteins and build multimodality molecular imaging probes. The review starts from the general introduction of biocompatible reactions, which is followed by briefly describing the development of the firefly luciferin-inspired biocompatible chemistry...
October 25, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29029767/pet-ct-and-pet-mri-in-head-and-neck-malignancy
#7
REVIEW
T A Szyszko, G J R Cook
Combined 2-[(18)F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography (PET)/computed tomography (CT) has an established role in the staging of difficult cases of head and neck (HN) squamous cell carcinoma (SCC), looking for an unknown primary, assessing response post-chemotherapy at 3-6 months, and differentiating relapse from treatment effects in patients suspected to have tumour recurrence. The PET NECK trial, comparing PET/CT surveillance versus neck dissection in advanced head and neck cancer showed survival was similar among patients who underwent PET/CT-guided surveillance and those who underwent planned neck dissection, but surveillance was more cost-effective...
October 10, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28963933/functional-surgery-in-pediatric-drug-resistant-posterior-cortex-epilepsy-electro-clinical-findings-cognitive-and-seizure-outcome
#8
A Sierra-Marcos, M C Fournier-Del Castillo, J Álvarez-Linera, M Budke, M García-Fernández, M A Pérez-Jiménez
PURPOSE: Epilepsies originated from the occipital, parietal and/or the posterior edge of the temporal lobe are grouped together into posterior cortex epilepsy (PCE). Our objective was firstly to describe electro-clinical and imaging findings in the presurgical evaluation of children with PCE, and secondly to identify potential factors associated with surgical and cognitive outcomes. METHOD: From the total of patients referred to the Epilepsy Monitoring Unit of 'Hospital Universitario Niño Jesús' from 2003 to 2016, 55 had drug-resistant PCE...
September 22, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28918564/mri-combined-with-pet-ct-of-different-tracers-to-improve-the-accuracy-of-glioma-diagnosis-a-systematic-review-and-meta-analysis
#9
REVIEW
Yihan Yang, Mike Z He, Tao Li, Xuejun Yang
Based on studies focusing on positron emission tomography (PET)-computed tomography (CT) combined with magnetic resonance imaging (MRI) in the diagnosis of glioma, we conducted a systematic review and meta-analysis evaluating the pros and cons and the accuracy of different examinations. PubMed and Cochrane Library were searched. The search was conducted until April 2017. Two reviewers independently conducted the literature search according to the criteria set initially. Based on the exclusion criteria, 15 articles are included in this study...
September 16, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28912705/corrigendum-multi-kernel-learning-with-dartel-improves-combined-mri-pet-classification-of-alzheimer-s-disease-in-aibl-data-group-and-individual-analyses
#10
Vahab Youssofzadeh, Bernadette McGuinness, Liam P Maguire, KongFatt Wong-Lin
[This corrects the article on p. 380 in vol. 11, PMID: 28790908.].
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28885539/a-comparison-of-18f-fdg-pet-mr-with-pet-ct-in-pulmonary-tuberculosis
#11
Benjamin A Thomas, James S Molton, Francesca Leek, Yan Pang, John J Totman, Nicholas I Paton, David W Townsend
PURPOSE: PET/computed tomography (CT) has been shown to detect lesions in patients with pulmonary tuberculosis (PTB) and may be useful for assessing PTB disease in clinical research studies. However, radiation dose is of concern for clinical research in individuals with an underlying curable disease. This study aimed to determine whether PET/MR is equivalent to PET/CT in PTB. MATERIALS AND METHODS: Ten patients with microbiologically confirmed PTB were recruited...
November 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28884750/brain-imaging-tests-for-chronic-pain-medical-legal-and-ethical-issues-and-recommendations
#12
REVIEW
Karen D Davis, Herta Flor, Henry T Greely, Gian Domenico Iannetti, Sean Mackey, Markus Ploner, Amanda Pustilnik, Irene Tracey, Rolf-Detlef Treede, Tor D Wager
Chronic pain is the greatest source of disability globally and claims related to chronic pain feature in many insurance and medico-legal cases. Brain imaging (for example, functional MRI, PET, EEG and magnetoencephalography) is widely considered to have potential for diagnosis, prognostication, and prediction of treatment outcome in patients with chronic pain. In this Consensus Statement, a presidential task force of the International Association for the Study of Pain examines the capabilities of brain imaging in the diagnosis of chronic pain, and the ethical and legal implications of its use in this way...
October 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28845826/diagnostic-imaging-and-workup-of-malignant-pleural-mesothelioma
#13
Luciano Cardinale, Francesco Ardissone, Dario Gned, Nicola Sverzellati, Edoardo Piacibello, Andrea Veltri
Malignant pleural mesothelioma is the most frequent primary neoplasm of the pleura and its incidence is still increasing.This tumor has a strong association with exposure to occupational or environmental asbestos, often after a long latent period of 30-40 years.Plain chest radiography (CXR) is usually the first-line radiologic examination, but the radiographic findings are nonspecific due to its limited contrast resolution and they need to be complemented by other imaging modalities such as computed tomography (CT), magnetic resonance Imaging (MRI), Positron emission tomography-computed tomography (PET-CT) and ultrasound (US)...
August 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28790908/multi-kernel-learning-with-dartel-improves-combined-mri-pet-classification-of-alzheimer-s-disease-in-aibl-data-group-and-individual-analyses
#14
Vahab Youssofzadeh, Bernadette McGuinness, Liam P Maguire, KongFatt Wong-Lin
Magnetic resonance imaging (MRI) and positron emission tomography (PET) are neuroimaging modalities typically used for evaluating brain changes in Alzheimer's disease (AD). Due to their complementary nature, their combination can provide more accurate AD diagnosis or prognosis. In this work, we apply a multi-modal imaging machine-learning framework to enhance AD classification and prediction of diagnosis of subject-matched gray matter MRI and Pittsburgh compound B (PiB)-PET data related to 58 AD, 108 mild cognitive impairment (MCI) and 120 healthy elderly (HE) subjects from the Australian imaging, biomarkers and lifestyle (AIBL) dataset...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28707543/pet-mri-knocking-on-the-doors-of-the-rich-and-famous
#15
REVIEW
Thomas Beyer, Marcus Hacker, Vicky Goh
Since 2010 the portfolio of positron emission tomography (PET)-based imaging has been expanded by industry with the introduction of combined whole-body PET/MRI systems with the intent of merging PET-based molecular imaging with the strengths of MRI. PET/MRI has created a lot of hype in the scientific community but comparatively little traction in the clinic. The first years of whole-body PET/MRI were used to address inherent technical challenges; however, it is now time to make use of the full potential of this integrated imaging modality...
August 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28686535/prospective-evaluation-of-magnetic-resonance-imaging-and-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-at-diagnosis-and-before-maintenance-therapy-in-symptomatic-patients-with-multiple-myeloma-included-in-the-ifm-dfci-2009-trial-results
#16
RANDOMIZED CONTROLLED TRIAL
Philippe Moreau, Michel Attal, Denis Caillot, Margaret Macro, Lionel Karlin, Laurent Garderet, Thierry Facon, Lotfi Benboubker, Martine Escoffre-Barbe, Anne-Marie Stoppa, Kamel Laribi, Cyrille Hulin, Aurore Perrot, Gerald Marit, Jean-Richard Eveillard, Florence Caillon, Caroline Bodet-Milin, Brigitte Pegourie, Veronique Dorvaux, Carine Chaleteix, Kenneth Anderson, Paul Richardson, Nikhil C Munshi, Herve Avet-Loiseau, Aurelie Gaultier, Jean-Michel Nguyen, Benoit Dupas, Eric Frampas, Françoise Kraeber-Bodere
Purpose Magnetic resonance imaging (MRI) and positron emission tomography-computed tomography (PET-CT) are important imaging techniques in multiple myeloma (MM). We conducted a prospective trial in patients with MM aimed at comparing MRI and PET-CT with respect to the detection of bone lesions at diagnosis and the prognostic value of the techniques. Patients and Methods One hundred thirty-four patients received a combination of lenalidomide, bortezomib, and dexamethasone (RVD) with or without autologous stem-cell transplantation, followed by lenalidomide maintenance...
September 1, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28621621/indications-technique-and-safety-profile-of-insular-stereoelectroencephalography-electrode-implantation-in-medically-intractable-epilepsy
#17
Soha Alomar, Jeffrey P Mullin, Saksith Smithason, Jorge Gonzalez-Martinez
OBJECTIVE Insular epilepsy is relatively rare; however, exploring the insular cortex when preoperative workup raises the suspicion of insular epilepsy is of paramount importance for accurate localization of the epileptogenic zone and achievement of seizure freedom. The authors review their clinical experience with stereoelectroencephalography (SEEG) electrode implantation in patients with medically intractable epilepsy and suspected insular involvement. METHODS A total of 198 consecutive cases in which patients underwent SEEG implantation with a total of 1556 electrodes between June 2009 and April 2013 were reviewed...
June 16, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28599998/-pet-scan-and-nmr-spectroscopy-for-the-differential-diagnosis-between-brain-radiation-necrosis-and-tumour-recurrence-after-stereotactic-irradiation-of-brain-metastases-place-in-the-decision-tree
#18
I Menoux, G Noël, I Namer, D Antoni
PURPOSE: After stereotactic radiation therapy for brain metastases, one of the complications is radionecrosis. Differential diagnosis with tumour recurrence can be helped by different methods of imaging, although histology remains the gold standard. According to the treatment centres, practice diverges. The objective of this single-centre retrospective study was to define the power of MRI, PET scan and NMR spectroscopy to establish a decision tree. MATERIAL AND METHODS: This study included patients who underwent stereotactic radiation therapy for brain metastases, and required, during follow-up, both a PET scan and NMR spectroscopy in order to differentiate a radiation necrosis and tumour recurrence...
August 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28595975/brain-molecular-imaging-in-pharmacoresistant-focal-epilepsy-current-practice-and-perspectives
#19
A Verger, S Lagarde, L Maillard, F Bartolomei, E Guedj
This review aims to synthesize all the available data on brain molecular imaging, such as single-photon emission computed tomography (SPECT) and interictal fluorodeoxyglucose positron emission tomography (FDG-PET), in focal epilepsies. SPECT imaging is able to measure regional cerebral blood flow and its major innovation remains its ictal imaging value. On the other hand, FDG-PET, which has higher spatial resolution and lower background activity than SPECT, enables glycolytic metabolism to be identified in interictal states...
June 5, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/28537412/-solid-pseudopapillary-neoplasms-of-the-pancreas
#20
J Tesaříková, M Loveček, Č Neoral, K Vomáčková, L Bébarová, P Skalický
INTRODUCTION: Solid pseudopapillary neoplasm (SPN) is a very rare neoplasm that occurs in girls and young women in 90% of cases; the range is 779 years of age, and the median is 28 years of age. This tumour was first described by Virginia Frantz in 1959 as a papillary cystic tumour of the pancreas. METHODS: The aim of this retrospective study was to analyse the incidence of SPN in all patients with a pancreatic tumour operated at the 1st Dept. of Surgery, University Hospital Olomouc between years 2006 and 2015...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
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