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https://www.readbyqxmd.com/read/27788123/osseointegration-of-three-dimensional-designed-titanium-implants-manufactured-by-selective-laser-melting
#1
Algabri Shaoki, Jia-Yun Xu, Haipeng Sun, Xian-Shuai Chen, Jianglin Ouyang, Xiu-Mei Zhuang, Fei-Long Deng
The selective laser melting (SLM) technique is a recent additive manufacturing (AM) technique. Several studies have reported success in the SLM-based production of biocompatible orthopaedic implants and three-dimensional bone defect constructs. In this study, we evaluated the surface properties and biocompatibility of an SLM titanium implant in vitro and compared them with those of a machined (MA) titanium control surface. In addition, we evaluated the osseointegration capability of the SLM implants in vivo and compared it with those of MA and Nobel-speedy (Nobel-S) implants...
October 27, 2016: Biofabrication
https://www.readbyqxmd.com/read/27782497/biomimetic-coatings-enhance-tribocorrosion-behavior-and-cell-responses-of-commercially-pure-titanium-surfaces
#2
Isabella da Silva Vieira Marques, Maria Fernanda Alfaro, Miki Taketomi Saito, Nilson Cristino da Cruz, Christos Takoudis, Richard Landers, Marcelo Ferraz Mesquita, Francisco Humberto Nociti Junior, Mathew T Mathew, Cortino Sukotjo, Valentim Adelino Ricardo Barão
Biofunctionalized surfaces for implants are currently receiving much attention in the health care sector. Our aims were (1) to create bioactive Ti-coatings doped with Ca, P, Si, and Ag produced by microarc oxidation (MAO) to improve the surface properties of biomedical implants, (2) to investigate the TiO2 layer stability under wear and corrosion, and (3) to evaluate human mesenchymal stem cells (hMSCs) responses cultured on the modified surfaces. Tribocorrosion and cell experiments were performed following the MAO treatment...
August 11, 2016: Biointerphases
https://www.readbyqxmd.com/read/27726837/-micro-porous-titanium-implants-in-orthognathic-facial-recontouring
#3
Jean-Baptiste Charrier, Nathan Moreau
INTRODUCTION: Facial symmetry has always been a longstanding objective of orthognathic surgery. Patients that present significant facial asymmetry desire functional dental occlusion but also seek to enhance their facial esthetics. In that regard, different surgical techniques have been proposed to enhance facial recontouring. MATERIALS AND METHODS: Through a clinical case report and a literature review, this article explores the use of allopastic microporous titanium implants in volumetric corrections of the face...
September 2016: L' Orthodontie Française
https://www.readbyqxmd.com/read/27612843/titanium-dental-implant-surfaces-obtained-by-anodic-spark-deposition-from-the-past-to-the-future
#4
REVIEW
Milena R Kaluđerović, Joachim P Schreckenbach, Hans-Ludwig Graf
Commercial titanium-based dental implants are obtained applying various methods such as machining, acid etching, anodization, plasma spraying, grit blasting or combination techniques yielding materials with smooth or micro-roughened surfaces. Those techniques are used to optimize the surface properties and to maximize biocompatibility and bioactivity with bone tissue. Present review is focused on the material surfaces obtained by anodic spark deposition (ASD). From the early 1980s till present, the results of numerous studies have shown that anodically oxidized surfaces with different dopants express a positive effect on osteoblasts behavior in vitro and osseointegration in vivo...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27556202/osseointegration-aspects-of-placed-implant-in-bone-reconstruction-with-newly-developed-block-type-interconnected-porous-calcium-hydroxyapatite
#5
Kazuya Doi, Takayasu Kubo, Yusuke Makihara, Hiroshi Oue, Koji Morita, Yoshifumi Oki, Shiho Kajihara, Kazuhiro Tsuga
OBJECTIVES: The purpose of this study was to evaluate the osseointegration of dental implant in bone reconstructions with interconnected porous calcium hydroxyapatite (IP-CHA). MATERIAL AND METHODS: The IP-CHA cylinders (D; 4.3 mm, H; 10.0 mm) were placed into bone sockets in each side of the femurs of four male dogs. The IP-CHA on the right side was a 24-week sample. Twelve weeks after placement, a titanium implant was placed into a socket that was prepared in half of the placed IP-CHA cylinder on the right side...
July 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/27514370/biomimetic-coatings-enhance-tribocorrosion-behavior-and-cell-responses-of-commercially-pure-titanium-surfaces
#6
Isabella da Silva Vieira Marques, Maria Fernanda Alfaro, Miki Taketomi Saito, Nilson Cristino da Cruz, Christos Takoudis, Richard Landers, Marcelo Ferraz Mesquita, Francisco Humberto Nociti Junior, Mathew T Mathew, Cortino Sukotjo, Valentim Adelino Ricardo Barão
Biofunctionalized surfaces for implants are currently receiving much attention in the health care sector. Our aims were (1) to create bioactive Ti-coatings doped with Ca, P, Si, and Ag produced by microarc oxidation (MAO) to improve the surface properties of biomedical implants, (2) to investigate the TiO2 layer stability under wear and corrosion, and (3) to evaluate human mesenchymal stem cells (hMSCs) responses cultured on the modified surfaces. Tribocorrosion and cell experiments were performed following the MAO treatment...
2016: Biointerphases
https://www.readbyqxmd.com/read/27501817/laser-sintered-constructs-with-bio-inspired-porosity-and-surface-micro-nano-roughness-enhance-mesenchymal-stem-cell-differentiation-and-matrix-mineralization-in-vitro
#7
Alice Cheng, David J Cohen, Barbara D Boyan, Zvi Schwartz
Direct metal laser sintering can produce porous Ti-6Al-4V orthopedic and dental implants. The process requires reduced resources and time and can provide greater structural control than machine manufacturing. Implants in bone are colonized by mesenchymal stem cells (MSCs), which can differentiate into osteoblasts and contribute to osseointegration. This study examined osteoblast differentiation and matrix mineralization of human MSCs cultured on laser-sintered Ti-6Al-4V constructs with varying porosity and at different time scales...
August 8, 2016: Calcified Tissue International
https://www.readbyqxmd.com/read/27475996/the-effects-of-diode-laser-on-staphylococcus-aureus-biofilm-and-escherichia-coli-lipopolysaccharide-adherent-to-titanium-oxide-surface-of-dental-implants-an-in-vitro-study
#8
Marco Giannelli, Giulia Landini, Fabrizio Materassi, Flaminia Chellini, Alberto Antonelli, Alessia Tani, Sandra Zecchi-Orlandini, Gian Maria Rossolini, Daniele Bani
Effective decontamination of biofilm and bacterial toxins from the surface of dental implants is a yet unresolved issue. This in vitro study aims at providing the experimental basis for possible use of diode laser (λ 808 nm) in the treatment of peri-implantitis. Staphylococcus aureus biofilm was grown for 48 h on titanium discs with porous surface corresponding to the bone-implant interface and then irradiated with a diode laser (λ 808 nm) in noncontact mode with airflow cooling for 1 min using a Ø 600-μm fiber...
November 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27439427/selective-laser-melting-of-titanium-alloy-enables-osseointegration-of-porous-multi-rooted-implants-in-a-rabbit-model
#9
Wei Peng, Liangwei Xu, Jia You, Lihua Fang, Qing Zhang
BACKGROUND: Osseointegration refers to the direct connection between living bone and the surface of a load-bearing artificial implant. Porous implants with well-controlled porosity and pore size can enhance osseointegration. However, until recently implants were produced by machining solid core titanium rods. The aim of this study was to develop a multi-rooted dental implant (MRI) with a connected porous surface structure to facilitate osseointegration. METHODS: MRIs manufactured by selective laser melting (SLM) and commercial implants with resorbable blasting media (RBM)-treated surfaces were inserted into the hind limbs of New Zealand white rabbits...
2016: Biomedical Engineering Online
https://www.readbyqxmd.com/read/27433617/biological-behavior-of-osteoblast-cell-and-apatite-forming-ability-of-the-surface-modified-ti-alloys
#10
Jingming Zhao, K H Hwang, W S Choi, S J Shin, J K Lee
Titanium as one kind of biomaterials comes in direct contact with the body, making evaluation of biocompatibility an important aspect to biomaterials development. Surface chemistry of titanium plays an important role in osseointegration. Different surface modification alters the surface chemistry and result in different biological response. In this study, three kinds of mixed acid solutions were used to treat Ti specimens to induce Ca-P formation. Following a strong mixed acid activation process, Ca-P coating successfully formed on the Ti surfaces in simulated body fluid...
February 2016: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/27185196/tantalum-implanted-entangled-porous-titanium-promotes-surface-osseointegration-and-bone-ingrowth
#11
Qi Wang, Yuqin Qiao, Mengqi Cheng, Guofeng Jiang, Guo He, Yunsu Chen, Xianlong Zhang, Xuanyong Liu
Porous Ti is considered to be an ideal graft material in orthopaedic and dental surgeries due to its similar spatial structures and mechanical properties to cancellous bone. In this work, to overcome the bioinertia of Ti, Ta-implanted entangled porous titanium (EPT) was constructed by plasma immersion ion implantation &deposition (PIII&D) method. Ca-implanted and unimplanted EPTs were investigated as control groups. Although no difference was found in surface topography and mechanical performances, both Ca- and Ta-implanted groups had better effects in promoting MG-63 cell viability, proliferation, differentiation, and mineralization than those of unimplanted group...
2016: Scientific Reports
https://www.readbyqxmd.com/read/26925568/-subantral-augmentation-with-porous-titanium-in-experiment-and-clinic
#12
S V Sirak, E V Shchetinin, A A Sletov
The article discusses the use of porous titanium for subantral augmentation. Experimental study was conducted on 12 yearling rams. Subantral augmentation using porous titanium was performed in 33 patients. In the control group consisting of 14 patients calcium phosphates and bone collagen based agents ("Bio-Оss" and "Collost") were used. In the main and control groups 46 and 32 implant were placed, respectively. Pilot histological and clinical studies proved that the granules of porous titanium are biocompatible with bone tissue, provide the optimal surface microrelief, thus creating good conditions for adhesion, expansion and migration of osteoforming cells, have negligible kinetics of resorption, are porous to ensure effective neovascularization of de novo formed bone tissue...
2016: Stomatologii︠a︡
https://www.readbyqxmd.com/read/26916451/influence-of-the-implant-diameter-and-bone-quality-on-the-primary-stability-of-porous-tantalum-trabecular-metal%C3%A2-dental-implants-an-in%C3%A2-vitro-biomechanical-study
#13
Georgios E Romanos, Rafael Arcesio Delgado-Ruiz, Danielle Sacks, Josè Luis Calvo-Guirado
OBJECTIVES: The aim of this study was to evaluate the primary, initial stability of Porous Tantalum Trabecular Metal(™) implants (TM) compared with Tapered Screw Vent(®) implants (TSV) with different diameters, inserted in two bone densities. METHODS: A total of 160 implants (80 TM and 80 TSV) with narrow (3.7 mm) and conventional (4.1 mm) diameters and the same length (10 mm) were placed in artificial bone blocks representing bone qualities II and IV. The implant stability was evaluated by insertion torque (IT) and Resonance Frequency Analysis...
February 24, 2016: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/26916052/micro-ct-based-modelling-for-characterising-injection-moulded-porous-titanium-implants
#14
Junning Chen, Liangjian Chen, Che-Cheng Chang, Zhongpu Zhang, Wei Li, Michael V Swain, Qing Li
Design of prosthetic implants to ensure rapid and stable osseointegration remains a significant challenge, and continuous efforts have been directed to new implant materials, structures and morphology. This paper aims to develop and characterise a porous titanium dental implant fabricated by metallic powder injection-moulding. The surface morphology of the specimens was firstly examined with a scanning electron microscope (SEM), followed by microscopic computerised tomography (μ-CT) scanning to capture its 3D microscopic features non-destructively...
February 25, 2016: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/26834277/electrochemical-behavior-of-bioactive-coatings-on-cp-ti-surface-for-dental-application
#15
Isabella da Silva Vieira Marques, Valentim Adelino Ricardo Barão, Nilson Cristino da Cruz, Judy Chia-Chun Yuan, Marcelo Ferraz Mesquita, Antonio Pedro Ricomini-Filho, Cortino Sukotjo, Mathew T Mathew
The surface characteristics and electrochemical properties of bioactive coatings produced by plasma electrolytic oxidation (PEO) with calcium, phosphorous, silicon and silver on commercially pure titanium were evaluated. PEO treatment produced a porous oxide layer, which improved the surface topography, and enriched the surface chemistry with bioactive elements, responsible for mimicking bone surface. The surfaces with higher calcium concentration presented antibacterial and biocompability properties with better responses for corrosion and barrier properties, due to the presence of rutile crystalline structure...
November 1, 2015: Corrosion Science
https://www.readbyqxmd.com/read/26802440/cell-laden-hydrogel-titanium-microhybrids-site-specific-cell-delivery-to-metallic-implants-for-improved-integration
#16
Geraldine Koenig, Hayriye Ozcelik, Lisa Haesler, Martina Cihova, Sait Ciftci, Agnes Dupret-Bories, Christian Debry, Martin Stelzle, Philippe Lavalle, Nihal Engin Vrana
UNLABELLED: Porous titanium implants are widely used in dental, orthopaedic and otorhinolaryngology fields to improve implant integration to host tissue. A possible step further to improve the integration with the host is the incorporation of autologous cells in porous titanium structures via cell-laden hydrogels. Fast gelling hydrogels have advantageous properties for in situ applications such as localisation of specific cells and growth factors at a target area without dispersion. The ability to control the cell types in different regions of an implant is important in applications where the target tissue (i) has structural heterogeneity (multiple cell types with a defined spatial configuration with respect to each other); (ii) has physical property gradients essential for its function (such as in the case of osteochondral tissue transition)...
March 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/26800574/effects-of-recombinant-human-bone-morphogenetic-protein-2-dose-and-ceramic-composition-on-new-bone-formation-and-space-maintenance-in-a-canine-mandibular-ridge-saddle-defect-model
#17
Anne D Talley, Kerem N Kalpakci, Daniel A Shimko, Katarzyna J Zienkiewicz, David L Cochran, Scott A Guelcher
Treatment of mandibular osseous defects is a significant clinical challenge. Maintenance of the height and width of the mandibular ridge is essential for placement of dental implants and restoration of normal dentition. While guided bone regeneration using protective membranes is an effective strategy for maintaining the anatomic contour of the ridge and promoting new bone formation, complications have been reported, including wound failure, seroma, and graft exposure leading to infection. In this study, we investigated injectable low-viscosity (LV) polyurethane/ceramic composites augmented with 100 μg/mL (low) or 400 μg/mL (high) recombinant human bone morphogenetic protein-2 (rhBMP-2) as space-maintaining bone grafts in a canine mandibular ridge saddle defect model...
March 2016: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/26789077/enhanced-osseointegration-of-hierarchical-micro-nanotopographic-titanium-fabricated-by-microarc-oxidation-and-electrochemical-treatment
#18
Guanglong Li, Huiliang Cao, Wenjie Zhang, Xun Ding, Guangzheng Yang, Yuqin Qiao, Xuanyong Liu, Xinquan Jiang
Rapid osseointegration is recognized as a critical factor in determining the success rate of orthopedic and dental implants. Microarc oxidation (MAO) fabricated titanium oxide coatings with a porous topography have been proven to be a potent approach to enhance osteogenic capacity. Now we report two kinds of new hierarchical coatings with similar micromorphologies but different nanotopographies (i.e., MAO and MAO-AK coatings), and both coatings significantly promote cell attachment and osteogenic differentiation through mediating the integrin β1 signaling pathway...
February 17, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/26773646/tribocorrosion-behavior-of-biofunctional-titanium-oxide-films-produced-by-micro-arc-oxidation-synergism-and-mechanisms
#19
Isabella da Silva Vieira Marques, Maria Fernanda Alfaro, Nilson Cristino da Cruz, Marcelo Ferraz Mesquita, Christos Takoudis, Cortino Sukotjo, Mathew T Mathew, Valentim Adelino Ricardo Barão
Dental implants, inserted into the oral cavity, are subjected to a synergistic interaction of wear and corrosion (tribocorrosion), which may lead to implant failures. The objective of this study was to investigate the tribocorrosion behavior of Ti oxide films produced by micro-arc oxidation (MAO) under oral environment simulation. MAO was conducted under different conditions as electrolyte composition: Ca/P (0.3M/0.02M or 0.1M/0.03M) incorporated with/without Ag (0.62g/L) or Si (0.04M); and treatment duration (5 and 10min)...
July 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/26665091/electrochemical-coating-of-dental-implants-with-anodic-porous-titania-for-enhanced-osteointegration
#20
Amirreza Shayganpour, Alberto Rebaudi, Pierpaolo Cortella, Alberto Diaspro, Marco Salerno
Clinical long-term osteointegration of titanium-based biomedical devices is the main goal for both dental and orthopedical implants. Both the surface morphology and the possible functionalization of the implant surface are important points. In the last decade, following the success of nanostructured anodic porous alumina, anodic porous titania has also attracted the interest of academic researchers. This material, investigated mainly for its photocatalytic properties and for applications in solar cells, is usually obtained from the anodization of ultrapure titanium...
2015: Beilstein Journal of Nanotechnology
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