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Deep lamellar

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https://www.readbyqxmd.com/read/28153495/efficient-internalization-of-tat-peptide-in-zwitterionic-dopc-phospholipid-membrane-revealed-by-neutron-diffraction
#1
Xiaochao Chen, Shutao Liu, Bruno Deme, Viviana Cristiglio, Drew Marquardt, Richard Weller, Pingfan Rao, Yunqiang Wang, Jeremy Bradshaw
The aim of this study is to investigate the interactions between TAT peptides and a neutral DOPC bilayer by using neutron lamellar diffraction. The distribution of TAT peptides and the perturbation of water distribution across the DOPC bilayer were revealed. When compared to our previous study on an anionic DOPC/DOPS bilayer (X. Chen et al., Biochim Biophys Acta. 2013. 1828 (8), 1982-1988), a much deeper insertion of TAT peptides was found in the hydrophobic core of DOPC bilayer at a depth of 6.0Å from the center of the bilayer, a position close to the double bond of fatty acyl chain...
January 30, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28138772/effect-of-corneal-collagen-crosslinking-on-subsequent-deep-anterior-lamellar-keratoplasty-dalk-in-keratoconus
#2
Friederike Schaub, Philip Enders, Björn O Bachmann, Ludwig M Heindl, Claus Cursiefen
PURPOSE: The purpose was to investigate the impact of ultraviolet light corneal collagen crosslinking (UV-CXL) on the success rate and clinical outcome of subsequent deep anterior lamellar keratoplasty (DALK) in eyes with keratoconus (KC). METHODS: Medical records of 101 consecutive eyes with KC scheduled for big-bubble DALK surgery were screened retrospectively for details of previously performed UV-CXL, as well as intra- and postoperative complications of DALK surgery...
January 30, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28099281/vision-related-quality-of-life-before-and-after-deep-anterior-lamellar-keratoplasty
#3
Elvin Yildiz, Meltem Toklu, Ece Turan Vural
OBJECTIVES: To determine changes in the vision-related quality of life in patients undergoing deep anterior lamellar keratoplasty (DALK) by using the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25). METHODS: Thirty-five patients who were scheduled for DALK between March 1, 2013, and March 1, 2014 were asked to complete the NEI VFQ-25. NEI VFQ-25 was administered again at 6 months and at 1 year postoperatively. Data on patients' age, sex, preoperative diagnosis, preoperative and postoperative best-corrected visual acuity, and postoperative astigmatism were recorded...
January 17, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28076561/visual-outcomes-after-deep-anterior-lamellar-keratoplasty-using-donor-corneas-without-removal-of-descemet-membrane-and-endothelium
#4
Tatiana Moura Bastos Prazeres, Rodrigo Muller, Tatiana Rayes, Flavio Eduardo Hirai, Luciene Barbosa de Sousa
Purpose: The optical quality of the interface after deep anterior lamellar keratoplasty (DALK) using the big-bubble technique has been shown to be excellent, leading to results comparable to penetrating keratoplasty. However, there is little in the literature with respect to the controversy surrounding the preparation of the donor cornea. The purpose of this study was to evaluate visual acuity (VA) in patients with keratoconus who underwent DALK without removal of the donor graft endothelium...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28017678/deep-anterior-lamellar-keratoplasty-after-descemet-stripping-automated-endothelial-keratoplasty
#5
Shay Gutfreund, Pia Leon, Shmuel Graffi, Massimo Busin
PURPOSE: To report the indications and long-term outcomes of deep anterior lamellar keratoplasty (DALK) performed after Descemet stripping automated endothelial keratoplasty (DSAEK) in cases of visually significant stromal opacities. DESIGN: Retrospective, interventional, consecutive case series. METHOD: Setting: Private hospital. Study populationThirteen eyes that underwent DALK after DSAEK at our Institution. Indications for DALK after DSAEK included both stromal opacities persisting after DSAEK and stromal opacities occurring secondarily in post-DSAEK corneas...
December 22, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28010938/deep-lamellar-endothelial-keratoplasty-clinical-outcome-the-13-to-18-year-follow-up
#6
Hilde C M Hooijmaijers, Marina Rodriguez-Calvo-de-Mora, Korine van Dijk, Lisanne Ham, Carla Nieuwendaal, Gerrit R J Melles
No abstract text is available yet for this article.
December 20, 2016: Ophthalmology
https://www.readbyqxmd.com/read/28004157/-deep-anterior-lamellar-keratoplasty-experiences-and-results-of-the-first-100-consecutive-dalk-from-the-university-eye-hospital-of-cologne
#7
F Schaub, L M Heindl, P Enders, S Roters, B O Bachmann, C Cursiefen
BACKGROUND: Deep anterior lamellar keratoplasty (DALK) is a treatment option for patients with diseases of the corneal stroma without endothelial involvement and has been used at the Department of Ophthalmology of the University of Cologne since July 2011. Experiences and results of the first 100 consecutive cases from Cologne with a minimum follow-up of 1 year are summarized. MATERIALS AND METHODS: We included the first 100 consecutive DALKs. Indications for anterior lamellar keratoplasty, the feasibility of the surgery, the postoperative course, in addition to the complications and clinical outcome 3 months after complete suture removal, were examined...
December 21, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28003975/preoperative-evaluation-and-outcome-of-corneal-transplantation-for-limbal-dermoids-a-ten-year-follow-up-study
#8
Meng Xin, Yue-Rong Gong, Shan-Hao Jiang, Chun-Hua Dai, Su-Xia Li, Wei-Yun Shi
AIM: To summarize preoperative evaluation and outcome of corneal transplantation for limbal dermoids for ten years. METHODS: Eighty-five patients diagnosed with limbal dermoids and treated with corneal transplantation were analyzed retrospectively. All patients were further divided into two groups according to absence or presence of neovascularization surrounding the dermoids in the corneal stroma. Eighty-two eyes were treated with tumor excision combined with partial lamellar sclerokeratoplasty, and the other three eyes were performed by penetrating keratoplasty...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28002112/wet-peeling-technique-of-deep-anterior-lamellar-keratoplasty-with-hypotonic-water-and-blunt-dissection-for-healed-hydrops
#9
Zelin Zhao, Jinyang Li, Qinxiang Zheng, Wei Lin, Vishal Jhanji, Wei Chen
PURPOSE: To describe the surgical technique and outcomes of "wet-peeling" deep anterior lamellar keratoplasty (DALK) using sterile water and blunt dissection in cases with corneal scarring after healed corneal hydrops. METHODS: Manual DALK using a "wet-peeling" technique was performed in 20 eyes of 20 consecutive patients with healed corneal hydrops between June 2011 and October 2013. RESULTS: Intraoperative microperforations were encountered in 2 (10%) cases...
March 2017: Cornea
https://www.readbyqxmd.com/read/28002108/corneal-biomechanical-properties-after-penetrating-keratoplasty-or-deep-anterior-lamellar-keratoplasty-using-the-ocular-response-analyzer-a-meta-analysis
#10
Min-Shan Jiang, Jing-Yuan Zhu, Xue Li, Nan-Nan Zhang, Xue-Dian Zhang
PURPOSE: To evaluate the corneal biomechanical properties of patients who have undergone penetrating keratoplasty (PK) or deep anterior lamellar keratoplasty (DALK) using the ocular response analyzer. METHODS: Stata 13.0 SE was used for this meta-analysis. Studies in the literature that focused on corneal hysteresis (CH) or corneal resistance factor (CRF) after PK or DALK were retrieved by searching PubMed, Embase, Ovid, and Cochrane databases. We present the results as weighted mean difference (WMD) with a corresponding 95% confidence interval (CI)...
March 2017: Cornea
https://www.readbyqxmd.com/read/27982215/toxic-anterior-segment-syndrome-following-deep-anterior-lamellar-keratoplasty
#11
Neslihan Sevimli, Remzi Karadag, Ozgur Cakici, Huseyin Bayramlar, Seydi Okumus, Unsal Sari
We present the case of a 31-year-old patient with toxic anterior segment syndrome (TASS) that developed after undergoing deep anterior lamellar keratoplasty (DALK). She had keratoconus, and despite wearing hard contact lenses for many years in the left eye, her vision had deteriorated; therefore, DALK was performed on this eye. The preoperative visual acuity (VA) was finger counting at 3 m. Routine DALK was performed using the "big-bubble" technique. The corneal entry incision was hydrated at the end of the surgery, which was terminated by air injection into the anterior chamber...
September 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27980368/visual-outcomes-following-deep-anterior-lamellar-keratoplasty-in-granular-corneal-dystrophy-types-1-and-2
#12
Lia M Uit de Bosch, Susan Ormonde, Stuti L Misra
No abstract text is available yet for this article.
December 2016: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/27938949/dual-purpose-corneal-tissue-for-anterior-lamellar-keratoplasty-and-descemet-s-membrane-endothelial-keratoplasty
#13
C Larena Menant-Tay, Ronan Conlon, Salina Teja, Season Yeung, Joshua Teichman, Setareh Ziai, Kashif Baig
OBJECTIVE: To assess the intraoperative issues and surgical outcomes of preparing a single-donor corneal tissue for same-day use in both deep anterior lamellar keratoplasty (DALK) and Descemet's membrane endothelial keratoplasty (DMEK). DESIGN: Consecutive retrospective case series. PARTICIPANTS: Ten eyes of 10 patients who underwent DALK (5 patients) or DMEK (5 patients) surgery using dual-purpose corneal tissue. METHODS: Five dual-purpose corneoscleral rims were used to prepare tissue for 5 DMEK and 5 DALK procedures...
December 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27853010/femtosecond-laser-assisted-deep-anterior-lamellar-keratoplasty-with-big-bubble-technique-for-keratoconus
#14
Yan Lu, Xiangfei Chen, Liping Yang, Chunyan Xue, Zhenping Huang
PURPOSE: The purpose of this study was to evaluate the clinical results after deep anterior lamellar keratoplasty (DALK) assisted by the femtosecond laser with big-bubble technique for keratoconus. METHODS: A case series of 22 eyes in 19 patients with keratoconus was enrolled in the study. The 500-kHz VisuMax femtosecond laser (Carl Zeiss Meditec AG, Jena, Germany) was used to create a vertical side cut on donor and recipient corneas. Intraoperative and postoperative complications, uncorrected visual acuity, best-corrected visual acuity, corneal curvature, and central corneal thickness were evaluated in all patients...
September 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27843237/demonstration-of-cornea-dua-s-layer-at-a-deep-anterior-lamellar-keratoplasty-surgery
#15
Yusuf Koçluk, Ayşe Burcu, Emine Alyamaç Sukgen
The authors aimed to present a deep anterior lamellar keratoplasty (DALK) surgery case with mixed type bubble demonstrating Dua's layer (DL). This was a reported case of DALK surgery. The authors encountered cornea DL structure at DALK surgery while cleaning the remaining stromal pieces. We also observed perforation in the central part of DL. However, DALK surgery could be completed. It is possible to encounter DL in a DALK surgery performed with mixed type big-bubble.
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27818576/intraoperative-management-of-macroperforations-of-descemet-s-membrane-in-deep-anterior-lamellar-keratoplasty
#16
Bernhard Steger, Vito Romano, Christoph Palme, Stephen B Kaye
BACKGROUND: To describe a surgical approach for the completion of pre-descemetic deep anterior lamellar keratoplasty (pdDALK) in the presence of a macroperforation of Descemet's membrane (DM). METHODS: Using case notes, we recorded the details of the intra- and perioperative course of patients who underwent successful pdDALK in the presence of macroperforation. A literature search of pdDALK techniques available to the corneal surgeon in a similar scenario was undertaken...
2016: Spektrum der Augenheilkunde: Zeitschrift der Österreichischen Ophthalmologischen Gesellschaft, ÖOG
https://www.readbyqxmd.com/read/27802912/systematic-review-comparing-penetrating-keratoplasty-and-deep-anterior-lamellar-keratoplasty-for-management-of-keratoconus
#17
REVIEW
Christin Henein, Mayank A Nanavaty
AIM: Perception of reduced incidence of graft rejection after deep anterior lamellar keratoplasty (DALK) has attracted many surgeons towards this technique in keratoconus. This review aims to compare the visual, refractive and graft outcomes after penetrating keratoplasty (PK) and DALK for keratoconus. METHODS: Electronic searches of PubMed, MEDLINE, EMBASE, Latin American and Caribbean Health Sciences Literature database (LILACS), metaRegister of Controlled Trials (mRCT), ClinicalTrial...
February 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/27749448/cannula-dalk-versus-needle-dalk-for-keratoconus
#18
Enrica Sarnicola, Caterina Sarnicola, Francesco Sabatino, Gian M Tosi, Paolo Perri, Vincenzo Sarnicola
PURPOSE: To evaluate outcomes and possible advantages of 2 different techniques of deep anterior lamellar keratoplasty (DALK) in patients with keratoconus: cannula big-bubble DALK and needle big-bubble DALK (Anwar technique). METHODS: This is a retrospective, nonconsecutive, comparative study of 507 eyes affected by keratoconus that underwent DALK between 2002 and 2012. Needle DALK and cannula DALK techniques were performed in 266 eyes and 241 eyes, respectively...
October 5, 2016: Cornea
https://www.readbyqxmd.com/read/27749446/tectonic-descemet-stripping-automated-endothelial-keratoplasty-for-the-management-of-sterile-corneal-perforations-in-decompensated-corneas
#19
Yoav Nahum, Irit Bahar, Massimo Busin
PURPOSE: To report the use of Descemet stripping automated endothelial keratoplasty (DSAEK) for treatment of sterile corneal perforations accompanying endothelial decompensation. METHODS: In this multicenter interventional case series, we reviewed the medical records of all tectonic DSAEK surgeries performed at Villa Serena-Villa Igea private Hospitals (Forlì, Italy) and Rabin Medical Center (Petach Tikva, Israel) between January 2014 and March 2016. RESULTS: Three patients with endothelial decompensation and sterile corneal perforation (n = 2) or impending corneal perforation (n = 1) underwent DSAEK between 2014 and 2015 at Villa Igea Hospital, Forlì, Italy, and Rabin Medical Center, Petach Tikva, Israel...
October 5, 2016: Cornea
https://www.readbyqxmd.com/read/27688591/outcomes-of-keratoplasty-in-the-mucopolysaccharidoses-an-international-perspective
#20
Kaitlyn L Ohden, Susanne Pitz, Jane Ashworth, Augusto Magalhães, Diane R Marinho, Päivi Lindahl, Kristina Teär Fahnehjelm, C Gail Summers
OBJECTIVE: To describe visual outcomes after penetrating keratoplasty and deep anterior lamellar keratoplasty in patients with mucopolysaccharidoses. METHODS: This is a retrospective review of keratoplasty in consecutive patients from Brazil, England, Finland, Germany, Portugal, Sweden and the USA. All patients had corneal clouding due to mucopolysaccharidoses. Preoperative and postoperative visual outcome and ocular comorbidities were identified. Success was arbitrarily defined as any improvement in visual acuity or best-corrected visual acuity better than logarithm of the minimum angle of resolution 0...
September 28, 2016: British Journal of Ophthalmology
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