Kritika Subramanian, Brett Muench, Eugene Shostak, Amanda Coffey, Lady Sawoszczyk, Fei Gao, Adam Leep, Ramya Rajaram, John Hornung, Elisabeth O'Dwyer
BACKGROUND: Endobronchial valve placement is a minimally invasive option for treatment of patients with severe emphysema, by reducing lung volumes in lobes with both poor ventilation and perfusion; ventilation is determined by emphysematous scores and perfusion by quantitative lung perfusion imaging. CT-based fissure identifying artificial intelligence algorithms have recently demonstrated enhanced quantification of the perfusion in a 5-lobar analysis. We hypothesized that this newly developed algorithm may offer greater utility in determining target treatment lobes by supplementing the radiographic risk stratification initiated by the conventional emphysematous scores alone...
July 8, 2023: Clinical Physiology and Functional Imaging