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https://www.readbyqxmd.com/read/28342662/use-of-brca-mutation-test-in-the-u-s-2004-2014
#1
Fangjian Guo, Jacqueline M Hirth, Yu-Li Lin, Gwyn Richardson, Lyuba Levine, Abbey B Berenson, Yong-Fang Kuo
INTRODUCTION: BRCA mutation testing has been used for screening women at high risk of breast and ovarian cancer and for selecting the best treatment for those with breast cancer. To optimize the infrastructure and medical resources allocation for genetic testing, it is important to understand the use of BRCA mutation testing in the U.S. health system. METHODS: This retrospective cohort study included 53,254 adult women with insurance claims for BRCA mutation testing between 2004 and 2014 from Clinformatics(TM) Data Mart Database...
March 18, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28340502/trends-in-alcohol-consumption-among-older-americans-national-health-interview-surveys-1997-to-2014
#2
Rosalind A Breslow, I-Jen P Castle, Chiung M Chen, Barry I Graubard
BACKGROUND: The majority of U.S. older adults consume alcoholic beverages. The older population is projected to almost double by 2050. Substantially more drinkers are likely. PURPOSE: To describe gender-specific trends (1997 to 2014) in prevalence of drinking status (lifetime abstention, former drinking, current drinking [including average volume], and binge drinking) among U.S. adults ages 60+ by age group and birth cohort. METHODS: In the 1997 to 2014 National Health Interview Surveys, 65,303 respondents ages 60+ (31,803 men, 33,500 women) were current drinkers; 6,570 men and 1,737 women were binge drinkers...
March 24, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28340367/insulin-resistance-is-associated-with-carotid-intima-media-thickness-in-non-diabetic-subjects-a-cross-sectional-analysis-of-the-elsa-brasil-cohort-baseline
#3
Itamar S Santos, Márcio S Bittencourt, Alessandra C Goulart, Maria Inês Schmidt, Maria de Fátima H S Diniz, Paulo A Lotufo, Isabela M Benseñor
BACKGROUND AND AIMS: Epidemiological studies have analyzed the association between carotid intima-media thickness (CIMT) and insulin resistance, glucose levels or glycated hemoglobin with mixed results. We aimed to evaluate the association between CIMT and homeostasis model assessment - insulin resistance (HOMA-IR), fasting and post-load plasma glucose and glycated hemoglobin in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline. METHODS: We included 8028 participants (aged 35-74 years) without diabetes or overt cardiovascular disease who had complete CIMT data at baseline...
March 10, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28340108/cigarette-smoking-and-musculoskeletal-pain-severity-among-male-and-female-afghanistan-iraq-era-veterans
#4
Kimberly T Green, Sarah M Wilson, Paul A Dennis, Jennifer J Runnals, Rebecca A Williams, Lori A Bastian, Jean C Beckham, Eric A Dedert, Harold S Kudler, Kristy Straits-Tröster, Jennifer M Gierisch, Patrick S Calhoun
Objective.:  Cigarette smoking and musculoskeletal pain are prevalent among Department of Veterans Affairs (VA) health care system users. These conditions frequently co-occur; however, there is limited empirical information specific to Afghanistan/Iraq era veterans. The present study sought to examine gender differences in the association between cigarette smoking and moderate to severe musculoskeletal pain in US veterans with Afghanistan/Iraq era service. Methods.:  A random sample of 5,000 veterans with service after November 11, 2001, participated in a survey assessing health care needs and barriers to care...
March 14, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28339883/interventions-to-improve-immigrant-health-a-scoping-review
#5
Esperanza Diaz, Gaby Ortiz-Barreda, Yoav Ben-Shlomo, Michelle Holdsworth, Bukola Salami, Anu Rammohan, Roger Yat-Nork Chung, Sabu S Padmadas, Thomas Krafft
: Disparities in health between immigrants and their host populations have been described across countries and continents. Hence, interventions for improving health targeting general populations are not necessarily effective for immigrants. To conduct a systematic search of the literature evaluating health interventions for immigrants; to map the characteristics of identified studies including range of interventions, immigrant populations and their host countries, clinical areas targeted and reported evaluations, challenges and limitations of the interventions identified...
February 27, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28339571/depression-among-non-daily-smokers-compared-to-daily-smokers-and-never-smokers-in-the-united-states-an-emerging-problem
#6
Andrea H Weinberger, Misato Gbedemah, Melanie M Wall, Deborah S Hasin, Michael J Zvolensky, Michael Chaiton, Renee D Goodwin
Introduction: Depression is strongly associated with daily smoking. Yet, little is known about the association between depression and non-daily smoking. The aim of this study was to investigate the prevalence of past-year depression and changes in past-year depression over time among non-daily smokers, compared to daily smokers and never-smokers, overall and stratified by age, gender, income, nicotine dependence, and cigarettes per day. Methods: Data were drawn from the National Household Survey on Drug Use (NSDUH), an annual cross-sectional study of persons aged 12 and over (total study population N = 496 805)...
January 25, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28339323/media-coverage-of-fda-drug-safety-communications-about-zolpidem-a-quantitative-and-qualitative-analysis
#7
Steve Woloshin, Lisa M Schwartz, Sara Dejene, Paula Rausch, Gerald J Dal Pan, Esther H Zhou, Aaron S Kesselheim
FDA issues Drug Safety Communications (DSCs) to alert health care professionals and the public about emerging safety information affecting prescription and over-the-counter drugs. News media may amplify DSCs, but it is unclear how DSC messaging is transmitted through the media. We conducted a content analysis of the lay media coverage reaching the broadest audience to characterize the amount and content of media coverage of two zolpidem DSCs from 2013. After the first DSC, zolpidem news stories increased from 19 stories/week in the preceding 3 months to 153 following its release...
March 24, 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/28339298/evaluations-and-future-plans-after-casual-sexual-experiences-differences-across-partner-type
#8
Rose Wesche, Shannon E Claxton, Eva S Lefkowitz, Manfred H M van Dulmen
Casual sexual relationships and experiences (CSREs) are common among emerging adults, and their diversity may contribute to variability in their associations with mental health and future romantic relationship development. The present research used multiple regression analyses to examine how CSRE type (casual dating, friends with benefits [FWB], or booty call/one-night stand) is associated with short-term outcomes of these experiences, including positive and negative evaluations, plans to start a romantic relationship with a CSRE partner, and general plans for future CSREs...
March 24, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28339098/quality-of-life-with-cediranib-in-relapsed-ovarian-cancer-the-icon6-phase-3-randomized-clinical-trial
#9
Dan P Stark, Adrian Cook, Julia M Brown, Michael D Brundage, Andrew C Embleton, Richard S Kaplan, Fharat A Raja, Ann Marie W Swart, Galina Velikova, Wendi Qian, Jonathan A Ledermann
BACKGROUND: The ICON6 trial showed that cediranib, an oral inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, improved clinical outcomes for patients with platinum-sensitive relapsed ovarian cancer when it was used with chemotherapy and was continued as maintenance therapy. This study describes health-related quality of life (QOL) during the first year of treatment. METHODS: Four hundred fifty-six women were randomly allocated to receive standard chemotherapy only, chemotherapy with concurrent cediranib, or chemotherapy with cediranib administered concurrently and continued as maintenance...
March 24, 2017: Cancer
https://www.readbyqxmd.com/read/28338879/evidence-for-detection-bias-by-medication-use-in-a-cohort-study-of-breast-cancer-survivors
#10
Heidi S Wirtz, Gregory S Calip, Diana S M Buist, Julie R Gralow, William E Barlow, Shelly Gray, Denise M Boudreau
In previous studies, we found modestly decreased and increased risks of second breast cancer events with the use of statins and antibiotics, respectively, after adjustment for surveillance mammography. We evaluated detection bias by comparing receipt of surveillance mammography among users of these 2 disparate classes of medication. Adult women diagnosed with early-stage breast cancer during 1990-2008 (n = 3,965) while enrolled in an integrated health-care plan (Group Health Cooperative; Washington State) were followed for up to 10 years in the Commonly Used Medications and Breast Cancer Outcomes (COMBO) Study...
March 1, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28338878/risk-of-diabetes-after-hysterectomy-with-or-without-oophorectomy-in-postmenopausal-women
#11
Juhua Luo, JoAnn E Manson, Rachel Peragallo Urrutia, Michael Hendryx, Erin S LeBlanc, Karen L Margolis
The aim of this study was to determine the associations between hysterectomy, bilateral salpingo-oophorectomy (BSO), and incidence of diabetes in postmenopausal women participating in the Women's Health Initiative (WHI), a series of trials conducted in the United States, during the period 1993-1998. A total of 67,130 postmenopausal women aged 50-79 years were followed for a mean of 13.4 years. Among them, 7,430 cases of diabetes were diagnosed. Multivariable Cox proportional hazards models were used to assess the association between hysterectomy/oophorectomy status and diabetes incidence...
March 6, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28338863/attendance-at-religious-services-prayer-religious-coping-and-religious-spiritual-identity-as-predictors-of-all-cause-mortality-in-the-black-women-s-health-study
#12
Tyler J VanderWeele, Jeffrey Yu, Yvette C Cozier, Lauren Wise, M Austin Argentieri, Lynn Rosenberg, Julie R Palmer, Alexandra E Shields
Previous longitudinal studies have consistently shown an association between attendance at religious services and lower all-cause mortality, but the literature on associations between other measures of religion and spirituality (R/S) and mortality is limited. We followed 36,613 respondents from the Black Women's Health Study from 2005 through December 31, 2013 to assess the associations between R/S and incident all-cause mortality using proportional hazards models. After control for numerous demographic and health covariates, together with other R/S variables, attending religious services several times per week was associated with a substantially lower mortality rate ratio (mortality rate ratio = 0...
March 3, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28338663/prevalence-and-associated-factors-of-blepharoptosis-in-korean-adult-population-the-korea-national-health-and-nutrition-examination-survey-2008-2011
#13
M H Kim, J Cho, D Zhao, K I Woo, Y-D Kim, S Kim, S W Yang
PurposeThis study aimed to evaluate the prevalence and associated factors of involutional blepharoptosis in a nationwide representative sample in Korea.MethodsCross-sectional study 20 941 Korean men and women 40 years of age and older who participated in last 2 years (2008 and 2009) of the 4th wave of the Korean National Health and Nutrition Examination Survey (KNHANES) IV and the first 2 years (2010 and 2011) of KNHANES V. Ocular examinations were performed by ophthalmologists trained in procedure and grading methods, and blepharoptosis was defined as a marginal reflex distance <2 mm on either eye...
March 24, 2017: Eye
https://www.readbyqxmd.com/read/28338611/disability-and-psychiatric-symptoms-in-men-referred-for-treatment-with-work-related-problems-to-primary-mental-health-care
#14
S Kathleen Bailey, Christopher J Mushquash, John M Haggarty
The relationship between male sex and employment as barriers to accessing mental health care is unclear. The aim of this research was to examine (1) whether the clinical features of men referred to a shared mental health care (SMHC) service through primary care differed when symptoms were affecting them in the work domain; and (2) empirically re-evaluate the effectiveness of a SMHC model for work-related disability using a pre-post chart review of N = 3960 referrals to SMHC. ANOVA and logistic regression were performed to examine symptoms (Patient Health Questionnaire, PHQ) and disability (World Health Organization Disability Assessment Schedule, WHODAS 2) at entry and discharge...
March 24, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28337818/exploration-of-information-and-support-needs-in-relation-to-health-concerns-diet-and-physical-activity-in-colorectal-cancer-survivors
#15
S J Hardcastle, C Maxwell-Smith, M S Hagger, M O'Connor, C Platell
The purpose of the current study was to explore colorectal cancer survivors' information and support needs in relation to health concerns and health behaviour change. Face-to-face interviews were conducted with participants who had completed active treatment for cancer within the previous 2 years. Participants were colorectal cancer survivors (N = 24, men = 11, women = 13 M, age = 69.38 years, SD = 4.19) recruited from a hospital in Perth, Australia on the basis that they had existing morbidities that put them at increased risk of cardiovascular disease...
March 24, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28337687/assessing-the-culture-of-residency-using-the-c-change-resident-survey-validity-evidence-in-34-u-s-residency-programs
#16
Linda H Pololi, Arthur T Evans, Janet T Civian, Sandy Shea, Robert T Brennan
BACKGROUND: A practical instrument is needed to reliably measure the clinical learning environment and professionalism for residents. OBJECTIVE: To develop and present evidence of validity of an instrument to assess the culture of residency programs and the clinical learning environment. DESIGN: During 2014-2015, we surveyed residents using the C - Change Resident Survey to assess residents' perceptions of the culture in their programs. PARTICIPANTS: Residents in all years of training in 34 programs in internal medicine, pediatrics, and general surgery in 14 geographically diverse public and private academic health systems...
March 23, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28335075/breastmilk-with-a-high-omega-6-to-omega-3-fatty-acid-ratio-induced-cellular-events-similar-to-insulin-resistance-and-obesity-in-3t3-l1-adipocytes
#17
H Vaidya, S K Cheema
BACKGROUND: An imbalance of omega (n)-3 and n-6 polyunsaturated fatty acids (PUFA) during critical periods of development may have adverse effects on the health of the newborn in later life. OBJECTIVES: We hypothesized that breastmilk with higher n-6 to n-3 PUFA ratio will have higher inflammatory cytokines and initiate cellular events similar to insulin resistance and obesity. METHODS: Breastmilk was collected from healthy women who gave natural birth at full term...
March 23, 2017: Pediatric Obesity
https://www.readbyqxmd.com/read/28335004/barriers-and-facilitators-for-institutional-delivery-among-poor-mesoamerican-women-a-cross-sectional-study
#18
Bernardo Hernandez, Danny V Colombara, Marielle C Gagnier, Sima S Desai, Annie Haakenstad, Casey Johanns, Claire R McNellan, Jennifer Nelson, Erin B Palmisano, Diego Ríos-Zertuche, Alexandra Schaefer, Paola Zúñiga-Brenes, Emma Iriarte, Ali H Mokdad
Professional skilled care has shown to be one of the most promising strategies to reduce maternal mortality, and in-facility deliveries are a cost-effective way to ensure safe births. Countries in Mesoamerica have emphasized in-facility delivery care by professionally skilled attendants, but access to good-quality delivery care is still lacking for many women. We examined the characteristics of women who had a delivery in a health facility and determinants of the decision to bypass a closer facility and travel to a distant one...
March 15, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28334763/the-challenge-of-identifying-family-medicine-patients-with-obstructive-sleep-apnea-addressing-the-question-of-gender-inequality
#19
Sally Bailes, Catherine S Fichten, Dorrie Rizzo, Marc Baltzan, Roland Grad, Alan Pavilanis, Laura Creti, Rhonda Amsel, Eva Libman
Purpose.: The purpose of this study was to examine the sleep characteristics, metabolic syndrome disease and likelihood of obstructive sleep apnea in a sample of older, family medicine patients previously unsuspected for sleep apnea. Methods.: A total of 295 participants, minimum age 45, 58.7% women, were recruited from two family medicine clinics. None previously had been referred for sleep apnea testing. All participants completed a sleep symptom questionnaire and were offered an overnight polysomnography study, regardless of questionnaire results...
February 23, 2017: Family Practice
https://www.readbyqxmd.com/read/28333912/quickstats-percentage-of-u-s-women-aged-50-74-years-who-never-had-a-mammogram-%C3%A2-by-place-of-birth-and-length-of-residence-in-the-united-states-%C3%A2-national-health-interview-survey-2013-and-2015-%C3%A2
#20
(no author information available yet)
In 2013 and 2015 combined, 5.4% of U.S. women aged 50-74 years had never received a mammogram in their lifetime. Foreign-born women were twice as likely as U.S.-born women to have never received a mammogram (9.5% versus 4.7%). Foreign-born women who lived in the United States for <25% of their lifetime were more than twice as likely to have never received a mammogram compared with those who resided in the U.S. for ≥25% of their lifetime (17.3% versus 7.9%).
March 24, 2017: MMWR. Morbidity and Mortality Weekly Report
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