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Early intervention autism

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https://www.readbyqxmd.com/read/29611405/vocalization-of-emotional-and-social-expressions-in-korean-speaking-toddlers-with-autism-spectrum-disorder-and-those-with-developmental-delay
#1
Kyung Sook Lee, Yee Jin Shin, Hee Jeong Yoo, Gui Jong Lee, Jeong Ryu, Oweol Son, Sook Whan Cho
PURPOSE: This study aimed to examine the development of socializing and emotional expressions through vocalizations and joint attention (JA) behaviors in Korean-speaking children with autism spectrum disorder (ASD), compared to those with developmental delay (DD). MATERIALS AND METHODS: Video samples were collected from 28 toddlers with ASD and 18 age-matched toddlers with DD, and vocalizations were each coded in detail for the purpose of this retrospective research...
May 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29608153/use-of-a-video-scoring-anchor-for-rapid-serial-assessment-of-social-communication-in-toddlers
#2
Natasha Marrus, Stefanie Kennon-McGill, Brooke Harris, Yi Zhang, Anne L Glowinski, John N Constantino
Reciprocal social behavior (RSB), an early-emerging capacity to engage in social contingency-which is foundational for both social learning and social competency-is hypothesized to be disrupted in autism spectrum disorder (ASD). The ability to quantify the full range of RSB during the toddler period, when core symptoms of ASD often arise, is pivotal for evaluating early risk for ASD, characterizing social development, and tracking response to early interventions. However, important parameters of variation in RSB-especially prior to the development of verbal language-can be nuanced and difficult to characterize using questionnaire-based methods...
March 14, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29574740/annual-research-review-the-state-of-autism-intervention-science-progress-target-psychological-and-biological-mechanisms-and-future-prospects
#3
REVIEW
Jonathan Green, Shruti Garg
BACKGROUND: There has been recent systematic review of key evidence in psychosocial intervention in autism but little review of biological treatments. METHODS: We analyse the current literature from the perspective of intervention and mechanism targets across social and biological development. RESULTS: The overall quality of trials evidence in autism intervention remains relatively low, despite some recent progress. Many treatments in common use have little or no evidence base...
April 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29574736/commentary-randomized-controlled-trials-in-autism-spectrum-disorder-state-of-the-field-and-challenges-for-the-future
#4
Emily Simonoff
This issue of the Journal includes two articles summarizing the evidence from clinical trials aimed at improving symptoms of autism. French and Kennedy (Journal of Child Psychology and Psychiatry, 2018, xx, xxxx) systematically review randomized controlled trials (RCTs) aimed at an "early intervention" and focus on trials including children with or at risk of autism under age 6 years. Although no type of intervention were excluded from their review, none of the included 48 RCTs employed pharmacological modalities and the overwhelming majority tested psychological/behavioural interventions aimed at modifying aspects of observed behaviours that are abnormal in children with autism...
April 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29573218/understanding-environmental-contributions-to-autism-causal-concepts-and-the-state-of-science
#5
REVIEW
Irva Hertz-Picciotto, Rebecca J Schmidt, Paula Krakowiak
The complexity of neurodevelopment, the rapidity of early neurogenesis, and over 100 years of research identifying environmental influences on neurodevelopment serve as backdrop to understanding factors that influence risk and severity of autism spectrum disorder (ASD). This Keynote Lecture, delivered at the May 2016 annual meeting of the International Society for Autism Research, describes concepts of causation, outlines the trajectory of research on nongenetic factors beginning in the 1960s, and briefly reviews the current state of this science...
March 23, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29558816/prenatal-primary-prevention-of-mental-illness-by-micronutrient-supplements-in-pregnancy
#6
Robert Freedman, Sharon K Hunter, M Camille Hoffman
Genes, infection, malnutrition, and other factors affecting fetal brain development are a major component of risk for a child's emotional development and later mental illnesses, including schizophrenia, bipolar disorder, and autism. Prenatal interventions to ameliorate that risk have yet to be established for clinical use. A systematic review of prenatal nutrients and childhood emotional development and later mental illness was performed. Randomized trials of folic acid, phosphatidylcholine, and omega-3 fatty acid supplements assess effects of doses beyond those adequate to remedy deficiencies to promote normal fetal development despite genetic and environmental risks...
March 21, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29544110/implications-of-comorbid-adhd-in-asd-interventions-and-outcome-results-from-a-naturalistic-follow-up-study-from-south-india
#7
Harshini Manohar, Pooja Patnaik Kuppili, Preeti Kandasamy, Venkatesh Chandrasekaran, Ravi Philip Rajkumar
BACKGROUND: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder commonly associated with Attention Deficit Hyperactivity Disorder (ADHD), the prevalence ranging from 14-70%. The current study attempted to assess the impact of comorbid ADHD in children with ASD, in terms of challenges in diagnosis, treatment, intervention outcomes and parental stress and coping through a naturalistic design. METHODS: Fifty children aged 2-6 years with ASD were recruited, assessed and followed up for six months...
March 2, 2018: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29543814/the-early-development-of-infant-siblings-of-children-with-autism-spectrum-disorder-characteristics-of-sibling-interactions
#8
Chloè Bontinck, Petra Warreyn, Sara Van der Paelt, Ellen Demurie, Herbert Roeyers
Although sibling interactions play an important role in children's early development, they are rarely studied in very young children with an older brother or sister with autism spectrum disorder (ASD). This study used a naturalistic, observational method to compare interactions between 18-month-old infants and their older sibling with ASD (n = 22) with a control group of 18-month-old infants and their typically developing (TD) older sibling (n = 29). In addition, role (a)symmetry and the influence of gender were evaluated...
2018: PloS One
https://www.readbyqxmd.com/read/29537331/efficacy-of-early-interventions-for-infants-and-young-children-with-and-at-risk-for-autism-spectrum-disorders
#9
Rebecca J Landa
With advances in the field's ability to identify autism spectrum disorders (ASD) at younger ages, the need for information about the evidence-base for early intervention continues to rise. This review of the ASD early intervention (EI) literature focuses on efficacy studies published within the past 15 years. The neurodevelopmental context for early intervention, timing of initiating intervention, primary intervention approaches, and predictors of treatment outcomes are discussed. The evidence indicates that young children with ASD benefit from EI, and their parents learn to implement child-responsive engagement strategies when a parent-coaching intervention is provided...
March 14, 2018: International Review of Psychiatry
https://www.readbyqxmd.com/read/29516450/-conduct-disorders-in-autism-spectrum-disorders
#10
A Hervas, I Rueda
INTRODUCTION: Autism spectrum disorders (ASD) are neurodevelopmental disorders that affect social communication and present stereotypic behaviours. Comorbidity associated to conduct disorders is frequent, starts in infancy and, in general, continues into adulthood. It is sometimes associated with aggressiveness, negativism, self-harm and breaking social norms. It causes a high degree of dysfunctionality in persons with ASD, their family, professionals and those around them, and is the main cause of pharmacological treatment, hospitalisation and special education...
March 1, 2018: Revista de Neurologia
https://www.readbyqxmd.com/read/29509308/a-new-measure-of-child-vocal-reciprocity-in-children-with-autism-spectrum-disorder
#11
Amy L Harbison, Tiffany G Woynaroski, Jon Tapp, Joshua W Wade, Anne S Warlaumont, Paul J Yoder
Children's vocal development occurs in the context of reciprocal exchanges with a communication partner who models "speechlike" productions. We propose a new measure of child vocal reciprocity, which we define as the degree to which an adult vocal response increases the probability of an immediately following child vocal response. Vocal reciprocity is likely to be associated with the speechlikeness of vocal communication in young children with autism spectrum disorder (ASD). Two studies were conducted to test the utility of the new measure...
March 6, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29500757/caregiver-mental-health-parenting-practices-and-perceptions-of-child-attachment-in-children-with-autism-spectrum-disorder
#12
Samantha J Teague, Louise K Newman, Bruce J Tonge, Kylie M Gray
This paper investigates the role of caregiver mental health and parenting practices as predictors of attachment in children with intellectual disability/developmental delay, comparing between children with ASD (n = 29) and children with other developmental disabilities (n = 20). Parents reported that children with ASD had high levels of anxiety and stress, and attachment insecurity in children (less closeness and more conflict in attachment relationships, and more inhibited attachment behaviours) compared with children with other developmental disabilities...
March 2, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29493557/motor-development-and-delay-advances-in-assessment-of-motor-skills-in-autism-spectrum-disorders
#13
Rujuta B Wilson, Peter G Enticott, Nicole J Rinehart
PURPOSE OF REVIEW: Motor impairments in neurodevelopmental disorders, specifically autism spectrum disorder (ASD), are prevalent and pervasive. Moreover, motor impairments may be the first sign of atypical development in ASD and likely contribute to abnormalities in social communication. However, measurement of motor function in ASD has lagged behind other behavioral phenotyping. Quantitative and neurodiagnostic measures of motor function can help identify specific motor impairments in ASD and the underlying neural mechanisms that might be implicated...
April 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29487501/a-review-of-oxytocin-and-arginine-vasopressin-receptors-and-their-modulation-of-autism-spectrum-disorder
#14
REVIEW
Ilaria Cataldo, Atiqah Azhari, Gianluca Esposito
Oxytocin ( OXT ) and arginine-vasopressin ( AVP ) play a key regulatory part in social and affiliative behaviors; two aspects highly compromised in Autism Spectrum Disorder (ASD). Furthermore, variants in the adjacent oxytocin-vasopressin gene regions have been found to be associated with ASD diagnosis and endophenotypes. This review focuses mainly on common OXTr single nucleotide polymorphisms (SNPs), AVPR1a microsatellites and AVPR1b polymorphisms in relation to the development of autism. Although these genes did not surface in genome-wide association studies, evidence supports the hypothesis that these receptors and their polymorphisms are widely involved in the regulation of social behavior, and in modulating neural and physiological pathways contributing to the etiology of ASD...
2018: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29485349/parental-experiences-using-the-therapy-outcomes-by-you-toby-application-to-deliver-early-intervention-to-their-child-with-autism
#15
Jessica Rogerson, Marita Falkmer, Belinda Cuomo, Torbjorn Falkmer, Andrew J O Whitehouse, Joanna Granich, Sharmila Vaz
PURPOSE: As computer-based interventions become commonplace for parents of children with neurodevelopmental disorders, this study sought to understand the experience of using a parent-delivered supplementary early intervention therapy for children with autism spectrum disorder grounded in a variety of behavioral, sensory, developmental, and relationship-based approaches and delivered via a tablet device. METHODS: Parental experiences using the 'Therapy Outcomes by You' (TOBY) application were collected through semi-structured interviews with 17 parents...
February 27, 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/29462954/autism-treatment-evaluation-checklist-atec-norms-a-growth-chart-for-atec-score-changes-as-a-function-of-age
#16
Shreyas Mahapatra, David Vyshedsky, Samantha Martinez, Benjamin Kannel, Julia Braverman, Stephen M Edelson, Andrey Vyshedskiy
Most early-intervention Autism Spectrum Disorder (ASD) clinical trials are limited by the availability of psychometric technicians who assess each child's abilities before and after therapeutic intervention. If parents could administer regular psychometric evaluations of their children, then the cost of clinical trials will be reduced, enabling longer clinical trials with the larger number of participants. The Autism Treatment Evaluation Checklist (ATEC) was designed nearly two decades ago to provide such a tool, but the norms on the longitudinal changes in ATEC in the "treatment as usual" population were lacking...
February 16, 2018: Children
https://www.readbyqxmd.com/read/29461904/an-investigation-of-the-association-between-seizures-autism-symptomology-and-developmental-functioning-in-young-children
#17
Claire O Burns, Johnny L Matson
OBJECTIVE: The aim of the present study was to explore whether a history of seizures was associated with autism symptom severity and developmental functioning in young children. METHODS: Autism symptom severity and developmental functioning were compared between children with and without a history or seizures who either had atypical development or met criteria for autism spectrum disorder (ASD) based on review of records by a licensed clinical psychologist. RESULTS: Parents of children who met criteria for ASD reported lower levels of autism symptomology when the child had a history of seizures, while the opposite trend was found for children with atypical development...
February 20, 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/29432106/a-feasibility-study-of-autism-behavioral-markers-in-spontaneous-facial-visual-and-hand-movement-response-data
#18
Manar D Samad, Norou Diawara, Jonna L Bobzien, John W Harrington, Megan A Witherow, Khan M Iftekharuddin
Autism spectrum disorder (ASD) is a neurodevelopmental disability with atypical traits in behavioral and physiological responses. These atypical traits in individuals with ASD may be too subtle and subjective to measure visually using tedious methods of scoring. Alternatively, the use of intrusive sensors in the measurement of psychophysical responses in individuals with ASD may likely cause inhibition and bias. This paper proposes a novel experimental protocol for non-intrusive sensing and analysis of facial expression, visual scanning, and eye-hand coordination to investigate behavioral markers for ASD...
February 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29427656/gut-microbiota-inflammation-and-probiotics-on-neural-development-in-autism-spectrum-disorder
#19
REVIEW
Ceymi Doenyas
Recent evidence implicates immune alterations and gut microbiota dysbiosis in at least some subpopulations of individuals with autism spectrum disorder (ASD). Immune and gut alterations in ASD have mostly been studied separately, and the reviews and theoretical models up to now have mainly considered the immune system as one of the routes for gut-brain communication. We take a different perspective and consider possible common mechanisms of action for the gut microbiota and inflammation on the neural basis of ASD...
March 15, 2018: Neuroscience
https://www.readbyqxmd.com/read/29412514/effects-of-parent-implemented-early-start-denver-model-intervention-on-chinese-toddlers-with-autism-spectrum-disorder-a-non-randomized-controlled-trial
#20
Bingrui Zhou, Qiong Xu, Huiping Li, Ying Zhang, Yi Wang, Sally J Rogers, Xiu Xu
To evaluate the effects of a 26-week, high-intensity, parent-implemented Early Start Denver Model (P-ESDM) intervention on developmental outcomes, severity of autism spectrum disorder (ASD), and parental stress of ASD toddlers in China. Subjects in P-ESDM group (n = 23) were recruited from 1.5- to 2.5-year-old toddlers who were screened positive in Xuhui and Minhang Districts and were diagnosed with ASD. A community (comparison) group of age-matched toddlers with ASD (n = 20) was recruited from other areas...
February 7, 2018: Autism Research: Official Journal of the International Society for Autism Research
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