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Early intervention autism

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https://www.readbyqxmd.com/read/28344643/goliah-gaming-open-library-for-intervention-in-autism-at-home-a-6-month-single-blind-matched-controlled-exploratory-study
#1
Anne-Lise Jouen, Antonio Narzisi, Jean Xavier, Elodie Tilmont, Nicolas Bodeau, Valentina Bono, Nabila Ketem-Premel, Salvatore Anzalone, Koushik Maharatna, Mohamed Chetouani, Filippo Muratori, David Cohen
BACKGROUND: To meet the required hours of intensive intervention for treating children with autism spectrum disorder (ASD), we developed an automated serious gaming platform (11 games) to deliver intervention at home (GOLIAH) by mapping the imitation and joint attention (JA) subset of age-adapted stimuli from the Early Start Denver Model (ESDM) intervention. Here, we report the results of a 6-month matched controlled exploratory study. METHODS: From two specialized clinics, we included 14 children (age range 5-8 years) with ASD and 10 controls matched for gender, age, sites, and treatment as usual (TAU)...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/28339168/parental-relationship-satisfaction-in-families-of-children-with-autism-spectrum-disorder-asd-a-multilevel-analysis
#2
Emma Langley, Vasiliki Totsika, Richard P Hastings
Caring for a child with Autism Spectrum Disorder (ASD) has been linked to a range of negative outcomes for parents but less is known about the putative impact upon the parental couple relationship. The relationship satisfaction of parents of children with ASD was investigated using multilevel modeling. Mothers and fathers (146 couples) reported on their relationship satisfaction, their own well-being, and the behavior problems of the child with ASD and a sibling. Results indicated that mothers and fathers reported similar levels of relationship satisfaction and it was significantly and negatively associated with parental depression and the behavior problems of the child with ASD...
March 24, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28335875/age-at-first-identification-of-autism-spectrum-disorder-an-analysis-of-two-us-surveys
#3
R Christopher Sheldrick, Melissa P Maye, Alice S Carter
OBJECTIVE: Evidence regarding the age at which autism spectrum disorder (ASD) is identified is essential for improving early detection, yet many extant studies have not applied time-to-event analyses, which account for statistical biases that arise from sampling in cross-sectional surveys by adjusting for child age at time of parental report. Our objective was to estimate age distributions for first identification of ASD in national parent surveys using time-to-event analyses. METHOD: We conducted time-to-event analyses of responses to identical questions in the 2011 to 2012 National Survey of Children's Health (n = 95,677) and the 2009 to 2010 National Survey of Children with Special Health Care Needs (n = 371,617)...
April 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28301083/age-specific-autistic-like-behaviors-in-heterozygous-fmr1-ko-female-mice
#4
Manon Gauducheau, Valerie Lemaire-Mayo, Francesca R D'Amato, Diego Oddi, Wim E Crusio, Susanna Pietropaolo
Fragile X syndrome (FXS) is a major developmental disorder and the most frequent monogenic cause of autism. Surprisingly, most existing studies on the Fmr1-KO mouse model for FXS have focused on males, although FX women, who are mostly heterozygous for the Fmr1 mutation, are known to exhibit several behavioral deficits, including autistic-like features. Furthermore, most animal research has been carried out on adults only; so that little is known about the age progression of the behavioral phenotype of Fmr1 mutants, which is a crucial issue to optimize the impact of therapeutic interventions...
March 16, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28299159/autism-spectrum-disorder-in-a-community-based-sample-with-neurodevelopmental-problems-in-lagos-nigeria
#5
Yewande O Oshodi, Andrew T Olagunju, Motunrayo A Oyelohunnu, Elizabeth A Campbell, Charles S Umeh, Olatunji F Aina, Wellington Oyibo, Folusho E A Lesi, Joseph D Adeyemi
Autism Spectrum Disorder (ASD) is a globally prevalent neurodevelopmental disorder for which early diagnosis and intervention is the mainstay of management. In the African continent, limited data is available regarding the non-clinic based samples. Lack of information available to caregivers and inadequate skilled manpower often limit early detection and access to the few available though under resourced services in the community. Community based screening can be an important drive to create awareness and improve information dissemination regarding services available for those living with this disorder...
December 31, 2016: Journal of Public Health in Africa
https://www.readbyqxmd.com/read/28285893/motor-and-verbal-perspective-taking-in-children-with-autism-spectrum-disorder-changes-in-social-interaction-with-people-and-tools
#6
Breanna E Studenka, Sandra L Gillam, Daphne Hartzheim, Ronald B Gillam
BACKGROUND: Children with Autism Spectrum Disorder (ASD) have difficulty communicating with others nonverbally, via mechanisms such as hand gestures, eye contact and facial expression. Individuals with ASD also have marked deficits in planning future actions (Hughes, 1996), which might contribute to impairments in non-verbal communication. Perspective taking is typically assessed using verbal scenarios whereby the participant imagines how an actor would interact in a social situation (e...
March 9, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28285719/-exploring-joint-attention-processes-in-young-children-with-autism-spectrum-disorder
#7
A de Gaulmyn, R Miljkovitch, M Montreuil
OBJECTIVES: Symptoms in autism, a neurodevelopmental disorder, appear at an early age. Research consensus shows impairments in communication and especially joint attention, defined as the capacity to intentionally share attention between two persons or a person and an object. Recent studies in autism spectrum disorder (ASD) focus on infants' processes associated to joint attention, such as visual and auditive regulation, attentional engagement and social motivation. The present research's objective is to examine the role of these factors in joint attention...
March 9, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28269617/smart-autism-a-mobile-interactive-and-integrated-framework-for-screening-and-confirmation-of-autism
#8
Khondaker Abdullah Al Mamun, Sharmistha Bardhan, Md Anwar Ullah, Evdokia Anagnostou, Jessica Brian, Shaheen Akhter, Mohammod Golam Rabbani
Smart Autism is a cloud based, automated framework for autism screening and confirmation. In developing countries, due to lack of resources and expertise, autism is detected later than early ages which consequently delays timely intervention. Therefore a mobile, interactive and integrated framework is proposed to screen and confirm autism in different age group (0 to 17 years) with 3 layers of assessment process. Firstly, it screens by evaluating the responses of pictorial based screening questionnaire through mobile application...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28266791/autism-spectrum-disorder-in-sub-saharan-africa-a-comprehensive-scoping-review
#9
REVIEW
Lauren Franz, Nola Chambers, Megan von Isenburg, Petrus J de Vries
Autism spectrum disorder (ASD) is recognized as a global public health concern, yet almost everything we know about ASD comes from high-income countries. Here we performed a scoping review of all research on ASD ever published in sub-Saharan Africa (SSA) in order to identify ASD knowledge gaps in this part of the world. Fifty-three publications met inclusion criteria. Themes included the phenotype, genetics and risk factors for ASD in SSA, screening and diagnosis, professional knowledge, interventions for ASD, parental perceptions, and social-cognitive neuroscience...
March 7, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28262133/lost-time-need-for-more-awareness-in-early-intervention-of-autism-spectrum-disorder
#10
Dr Preeti K, Dr Shoba Srinath, Dr Shekhar P Seshadri, Dr Satish C Girimaji, Dr John Vijay Sagar Kommu
Delay in the diagnosis and early intervention for Autism spectrum disorders has been observed across cultures and within the same cultural context. With the current evidence base for early intervention there is a need for greater awareness for early recognition, evaluation and intervention. This brief report discusses the average age at recognition to initiation of intervention and possible ways to address delay. Since early intervention programs for ASD results in favourable outcome, it would be good practice to routinely screen children at first consultation and initiate intervention in any child suspected to be 'At Risk' for ASD...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28256684/-models-for-intervention-in-autism-spectrum-disorders-denver-and-scerts
#11
C Forment-Dasca
INTRODUCTION: Given the increased prevalence of diagnoses of autism in recent years, the growing amount of research on models with which to work with people with autism spectrum disorders (ASD) has led to the development of different techniques and methods enabling better results to be obtained. As a result, it has become possible to help improve many of the symptoms that prevent people with this diagnosis and their families from leading a normal life. AIMS: To review two intervention models specifically designed for working with persons with ASD...
February 24, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28256376/-autism-an-early-neurodevelopmental-disorder
#12
F Bonnet-Brilhault
With approximately 67 million individuals affected worldwide, autism spectrum disorder (ASD) is the fastest growing neurodevelopmental disorder (United Nations, 2011), with a prevalence estimated to be 1/100. In France ASD affects approximately 600,000 individuals (from childhood to adulthood, half of whom are also mentally retarded), who thus have a major handicap in communication and in adapting to daily life, which leads autism to be recognized as a national public health priority. ASD is a neurodevelopmental disorder that affects several domains (i...
April 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28254668/inconsistent-staffing-and-its-impact-on-service-delivery-in-asd-early-intervention
#13
Rhylee Sulek, David Trembath, Jessica Paynter, Deb Keen, Kate Simpson
BACKGROUND: Inconsistent staffing (high turnover, casual workforce) is problematic in organisations, with the potential to impact both staff and services provided. Research has primarily focused on the impacts of inconsistent staffing in child welfare and community services with little evidence surrounding their ability to impact the outcomes for children with Autism Spectrum Disorders attending early-intervention services. AIM: The aim of this study was to explore staff views regarding the impact of staff turnover on the delivery of group based early intervention for children with ASD...
February 27, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28244271/parent-delivered-early-intervention-in-infants-at-risk-for-asd-effects-on-electrophysiological-and-habituation-measures-of-social-attention
#14
Emily J H Jones, Geraldine Dawson, Jean Kelly, Annette Estes, Sara Jane Webb
Prospective longitudinal studies of infants with older siblings with autism spectrum disorder (ASD) have indicated that differences in the neurocognitive systems underlying social attention may emerge prior to the child meeting ASD diagnostic criteria. Thus, targeting social attention with early intervention might have the potential to alter developmental trajectories for infants at high risk for ASD. Electrophysiological and habituation measures of social attention were collected at 6, 12, and 18 months in a group of high-risk infant siblings of children with ASD (N = 33)...
February 28, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28236851/infant-acetylcholine-dopamine-and-melatonin-dysregulation-neonatal-biomarkers-and-causal-factors-for-asd-and-adhd-phenotypes
#15
Kahl Hellmer, Pär Nyström
Autism spectrum disorders (ASD) and ADHD are common neurodevelopmental disorders that benefit from early intervention but currently suffer from late detection and diagnosis: neurochemical dysregulations are extant already at birth but clinical phenotypes are not distinguishable until preschool age or later. The vast heterogeneity between subjects' phenotypes relates to interaction between multiple unknown factors, making research on factor causality insurmountable. To unlock this situation we pose the hypothesis that atypical pupillary light responses from rods, cones, and the recently discovered ipRGC system reflect early acetylcholine, melatonin, and dopamine dysregulation that are sufficient but not necessary factors for developing ASD and/or ADHD disorders...
March 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28227875/smart-autism-a-mobile-interactive-and-integrated-framework-for-screening-and-confirmation-of-autism
#16
Khondaker Abdullah Al Mamun, Sharmistha Bardhan, Md Anwar Ullah, Evdokia Anagnostou, Jessica Brian, Shaheen Akhter, Mohammod Golam Rabbani, Khondaker Abdullah Al Mamun, Sharmistha Bardhan, Md Anwar Ullah, Evdokia Anagnostou, Jessica Brian, Shaheen Akhter, Mohammod Golam Rabbani, Evdokia Anagnostou, Sharmistha Bardhan, Shaheen Akhter, Md Anwar Ullah, Mohammod Golam Rabbani, Jessica Brian, Khondaker Abdullah Al Mamun
Smart Autism is a cloud based, automated framework for autism screening and confirmation. In developing countries, due to lack of resources and expertise, autism is detected later than early ages which consequently delays timely intervention. Therefore a mobile, interactive and integrated framework is proposed to screen and confirm autism in different age group (0 to 17 years) with 3 layers of assessment process. Firstly, it screens by evaluating the responses of pictorial based screening questionnaire through mobile application...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225070/speech-specific-categorical-perception-deficit-in-autism-an-event-related-potential-study-of-lexical-tone-processing-in-mandarin-speaking-children
#17
Xiaoyue Wang, Suiping Wang, Yuebo Fan, Dan Huang, Yang Zhang
Recent studies reveal that tonal language speakers with autism have enhanced neural sensitivity to pitch changes in nonspeech stimuli but not to lexical tone contrasts in their native language. The present ERP study investigated whether the distinct pitch processing pattern for speech and nonspeech stimuli in autism was due to a speech-specific deficit in categorical perception of lexical tones. A passive oddball paradigm was adopted to examine two groups (16 in the autism group and 15 in the control group) of Chinese children's Mismatch Responses (MMRs) to equivalent pitch deviations representing within-category and between-category differences in speech and nonspeech contexts...
February 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28221363/premature-primary-tooth-eruption-in-cognitive-motor-delayed-adnp-mutated-children
#18
I Gozes, A Van Dijck, G Hacohen-Kleiman, I Grigg, G Karmon, E Giladi, M Eger, Y Gabet, M Pasmanik-Chor, E Cappuyns, O Elpeleg, R F Kooy, S Bedrosian-Sermone
A major flaw in autism spectrum disorder (ASD) management is late diagnosis. Activity-dependent neuroprotective protein (ADNP) is a most frequent de novo mutated ASD-related gene. Functionally, ADNP protects nerve cells against electrical blockade. In mice, complete Adnp deficiency results in dysregulation of over 400 genes and failure to form a brain. Adnp haploinsufficiency results in cognitive and social deficiencies coupled to sex- and age-dependent deficits in the key microtubule and ion channel pathways...
February 21, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28220358/potential-risk-factors-for-the-development-of-self-injurious-behavior-among-infants-at-risk-for-autism-spectrum-disorder
#19
Adele F Dimian, Kelly N Botteron, Stephen R Dager, Jed T Elison, Annette M Estes, John R Pruett, Robert T Schultz, Lonnie Zwaigenbaum, Joseph Piven, Jason J Wolff
Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose of this study was to evaluate behavioral characteristics predicting SIB at age 2 years among 235 infants at high familial risk for ASD. Logistic regression results indicated that presence of SIB or proto-SIB and lower developmental functioning at age 12 months significantly predicted SIB at 24 months...
February 20, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28218869/child-behaviors-of-young-children-with-autism-spectrum-disorder-across-play-settings
#20
Megan MacDonald, Bridget Hatfield, Erica Twardzik
The hallmark characteristics of a diagnosis of autism spectrum disorder (ASD) are deficits in social communicative skills and the use of repetitive and/or stereotyped behaviors. In addition, children with ASD experience known motor-skill delays. The purpose of this study was to examine salient child behaviors of young children with and without ASD in 2 distinctly different play settings: a traditional social-play-based setting and a motor-behavior-based play setting. Child behavior (engagement toward parent, negativity, and attention) and dyad characteristics (connectedness) were examined in 2 distinctly different play settings...
January 2017: Adapted Physical Activity Quarterly: APAQ
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