keyword
https://read.qxmd.com/read/38648625/a-rapid-review-on-the-management-of-constipation-for-hospice-and-palliative-care-patients
#21
JOURNAL ARTICLE
Virpal Gill, Houman Badrzadeh, Sari Williams, Nadia Masroor Crouch, Sorin Buga, Stefanie Mooney, Tracy Fasolino
Constipation is a distressing symptom that has a high prevalence in patients receiving hospice and palliative care services, particularly in cases of opioid use. A thorough assessment, root cause analysis, monitoring, and prophylactic approach are essential for symptom management and quality of life. This rapid review assessed studies published between 2018 and 2023 to identify strategies implemented by health care professionals to prevent and/or mitigate this distressing symptom. We identified 12 articles that addressed constipation in palliative and end-of-life settings and reported on the need for multifactorial management approaches with a focus on patient-centered care that includes the caregiver(s)...
April 22, 2024: Journal of Hospice and Palliative Nursing: JHPN
https://read.qxmd.com/read/38648178/analysis-of-participant-stigma-and-associated-costs-of-a-peer-led-social-media-hiv-intervention
#22
JOURNAL ARTICLE
Navkiranjit Gill, Jim E Banta, Leonard Gashugi, Sean D Young
HIV-related stigma is a primary barrier to seeking HIV care. Online social media interventions utilizing peer-led approaches provide an opportunity to revolutionize HIV health behavior change. Secondary analysis of the UCLA HOPE Study (6 waves) was done to examine the effectiveness of an online peer-led intervention in reducing HIV-related internalized stigma (IS), association between IS and sexual risk behaviors (SRB), and associated costs for changing the likelihood of HIV testing. Among 897 participants, an inverse relationship between IS (Discomfort with people with HIV, Stereotypes, Moral Judgment) and SRB (Number of Sexual Partners, Sexual Encounters) factors was identified over time ( p < ...
April 2024: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://read.qxmd.com/read/38647533/effectiveness-of-the-online-based-comprehensive-cognitive-training-application-smart-brain-for-community-dwelling-older-adults-with-dementia-a-randomized-controlled-trial
#23
JOURNAL ARTICLE
Hee-Jae Chae, Seon-Heui Lee
BACKGROUND: The fourth industrial revolution has brought about developments in information and communication technologies for interventions in older adults with dementia. Currently, most interventions focus on single interventions. However, community-dwelling older adults with dementia require comprehensive cognitive interventions, and clinical studies analyzing the effects of comprehensive interventions based on randomized controlled trials are lacking. AIM: The aim of the study was to examine the effects of an information and communication technology-based comprehensive cognitive training program, Smart Brain, on multi-domain function among community-dwelling older adults with dementia...
April 22, 2024: European Journal of Physical and Rehabilitation Medicine
https://read.qxmd.com/read/38647465/genetic-and-subjective-sensitivity-relationship-dynamics-and-psychological-distress-in-couples
#24
JOURNAL ARTICLE
Samantha M Brown, Galena K Rhoades, Michael Pluess, Elizabeth S Allen, Scott M Stanley
Positive and negative aspects of intimate relationships influence mental health and well-being in couples. According to the environmental sensitivity framework, individuals differ in how strongly they are affected by their environment, with some individuals being more or less sensitive to both negative and positive experiences. The present study examined the longitudinal associations between positive and negative relationship dynamics, including marital satisfaction, positive bonding, and negative communication, and psychological distress as well as the extent to which individual differences in genetic and subjective measures of environmental sensitivity moderated the association between relationship dynamics and psychological distress in a sample of couples in the U...
April 22, 2024: Journal of Family Psychology: JFP
https://read.qxmd.com/read/38647274/swimming-exercise-protocol-and-care-methods-for-pregnant-rats
#25
JOURNAL ARTICLE
Ziqi Ni, Jiaqi Cao, Meiling Shan, Yanyan Zhang, Lijun Shi
The developmental origins of health and disease concept highlights the impact of early environments on chronic non-communicable diseases like diabetes, cardiovascular disease, and cancer. Studies using animal models have investigated how maternal factors such as undernutrition, overnutrition, obesity, and exposure to chemicals or hypoxia affect fetal development and offspring health, leading to issues like low birth weight, high blood pressure, dyslipidemia, and insulin resistance. Given the increasing prevalence of overweight and obesity among reproductive-age women, effective interventions are critical...
April 5, 2024: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/38646848/-to-have-a-plan-teachers-perceptions-of-working-with-a-literacy-instruction-combining-phonics-and-comprehension-applications-for-students-with-intellectual-disability-and-communication-difficulties
#26
JOURNAL ARTICLE
Jenny Samuelsson, Jakob Åsberg Johnels, Emil Holmer, Lisa Palmqvist, Mikael Heimann, Monica Reichenberg, Mats Lundälv, Gunilla Thunberg
PURPOSE: Students with intellectual disabilities (ID) typically have difficulties with literacy learning, often not acquiring basic literacy skills. Research and practical experience indicate that when these students are provided with evidence-based instruction, including comprehension as well as phonemic strategies, literacy may develop. METHODS: In this study, four pairs of teachers were interviewed regarding their perceptions of a 12-week digital literacy intervention that focused on both phonics and comprehension strategies...
April 22, 2024: Disability and Rehabilitation. Assistive Technology
https://read.qxmd.com/read/38646350/internal-herniation-of-the-transverse-colon-and-stricture-of-the-gastric-body-a-case-report
#27
Jacob B Morgan, Grace Corrier, Trevor Perry, Nicholas Hudspeth, Michael Garvie, Phillip Bradbury, Savannah Newell, John Lipka
Internal herniation is a protrusion of the bowel limited to the abdominal cavity. This pathology is rare and difficult to diagnose due to a wide array of symptoms that may manifest. Internal hernias have the potential to affect surrounding organs such as the stomach and adjacent bowel due to the compressive force of the protruding bowel. The effects of internal herniation commonly present in one of two ways: acute obstruction which requires emergent intervention and subacute, vague symptoms that are difficult to diagnose...
March 2024: Curēus
https://read.qxmd.com/read/38646277/the-relationship-between-resilience-and-the-intention-to-leave-among-staff-nurses-at-governmental-hospitals-in-the-al-baha-region-of-saudi-arabia
#28
JOURNAL ARTICLE
Sara Al-Shomrani, Sabah M Mahran, Ohood Felemban
Background Nurses with high intent to leave can cause substantial problems for healthcare organizations, such as staffing shortages and higher expenses due to hiring and onboarding new nurses. In light of the increasing demands placed on nurses in understaffed and overloaded healthcare systems, nurses frequently face various pressures and difficulties in their field of work, including high workloads, irregular hours, complicated patients, and infectious disease exposure; resilience is critical for handling stress and hardship at work...
March 2024: Curēus
https://read.qxmd.com/read/38646209/leveraging-artificial-intelligence-and-machine-learning-to-optimize-enhanced-recovery-after-surgery-eras-protocols
#29
EDITORIAL
Zukhruf Zain, Mohammed Khaleel I Kh Almadhoun, Lara Alsadoun, Syed Faqeer Hussain Bokhari
Enhanced recovery after surgery (ERAS) protocols have transformed perioperative care by implementing evidence-based strategies to hasten patient recovery, decrease complications, and shorten hospital stays. However, challenges such as inconsistent adherence and the need for personalized adjustments persist, prompting exploration into innovative solutions. The emergence of artificial intelligence (AI) and machine learning (ML) offers a promising avenue for optimizing ERAS protocols. While ERAS emphasizes preoperative optimization, minimally invasive surgery (MIS), and standardized postoperative care, challenges such as adherence variability and resource constraints impede its effectiveness...
March 2024: Curēus
https://read.qxmd.com/read/38646086/mapping-the-process-of-icu-care-delivery-to-improve-treatment-decisions-in-acute-respiratory-failure
#30
JOURNAL ARTICLE
Jacqueline M Kruser, Elizabeth M Viglianti, Ruben Mylvaganam, Kristyn A Krolikowski, Rebeca Khorzad, Michael E Detsky, Douglas A Wiegmann, Richard G Wunderink, Jane L Holl
Evidence suggests system-level norms and care processes influence individual patients' medical decisions, including end-of-life decisions for patients with critical illnesses like acute respiratory failure. Yet, little is known about how these processes unfold over the course of a patient's critical illness in the intensive care unit (ICU). Our objective was to map current-state ICU care delivery processes for patients with acute respiratory failure and to identify opportunities to improve the process. We conducted a process mapping study at two academic medical centers, using focus groups and semi-structured interviews...
2024: IISE Transactions on Healthcare Systems Engineering
https://read.qxmd.com/read/38646062/examining-the-effects-of-voluntary-avoidance-behaviour-and-policy-mediated-behaviour-change-on-the-dynamics-of-sars-cov-2-a-mathematical-model
#31
JOURNAL ARTICLE
Gabrielle Brankston, David N Fisman, Zvonimir Poljak, Ashleigh R Tuite, Amy L Greer
BACKGROUND: Throughout the SARS-CoV-2 pandemic, policymakers have had to navigate between recommending voluntary behaviour change and policy-driven behaviour change to mitigate the impact of the virus. While individuals will voluntarily engage in self-protective behaviour when there is an increasing infectious disease risk, the extent to which this occurs and its impact on an epidemic is not known. METHODS: This paper describes a deterministic disease transmission model exploring the impact of individual avoidance behaviour and policy-mediated avoidance behaviour on epidemic outcomes during the second wave of SARS-CoV-2 infections in Ontario, Canada (September 1, 2020 to February 28, 2021)...
September 2024: Infectious Disease Modelling
https://read.qxmd.com/read/38646061/epidemiological-feature-analysis-of-sveir-model-with-control-strategy-and-variant-evolution
#32
JOURNAL ARTICLE
Kaijing Chen, Fengying Wei, Xinyan Zhang, Hao Jin, Zuwen Wang, Yue Zuo, Kai Fan
The complex interactions were performed among non-pharmaceutical interventions, vaccinations, and hosts for all epidemics in mainland China during the spread of COVID-19. Specially, the small-scale epidemic in the city described by SVEIR model was less found in the current studies. The SVEIR model with control was established to analyze the dynamical and epidemiological features of two epidemics in Jinzhou City led by Omicron variants before and after Twenty Measures. In this study, the total population ( N ) of Jinzhou City was divided into five compartments: the susceptible ( S ), the vaccinated ( V ), the exposed ( E ), the infected ( I ), and the recovered ( R )...
September 2024: Infectious Disease Modelling
https://read.qxmd.com/read/38645696/optimal-decision-making-in-relieving-global-high-temperature-related-disease-burden-by-data-driven-simulation
#33
JOURNAL ARTICLE
Xin-Chen Li, Hao-Ran Qian, Yan-Yan Zhang, Qi-Yu Zhang, Jing-Shu Liu, Hong-Yu Lai, Wei-Guo Zheng, Jian Sun, Bo Fu, Xiao-Nong Zhou, Xiao-Xi Zhang
The rapid acceleration of global warming has led to an increased burden of high temperature-related diseases (HTDs), highlighting the need for advanced evidence-based management strategies. We have developed a conceptual framework aimed at alleviating the global burden of HTDs, grounded in the One Health concept. This framework refines the impact pathway and establishes systematic data-driven models to inform the adoption of evidence-based decision-making, tailored to distinct contexts. We collected extensive national-level data from authoritative public databases for the years 2010-2019...
June 2024: Infectious Disease Modelling
https://read.qxmd.com/read/38645174/placental-nanoparticle-mediated-igf1-gene-therapy-corrects-fetal-growth-restriction-in-a-guinea-pig-model
#34
Baylea N Davenport, Rebecca L Wilson, Alyssa A Williams, Helen N Jones
Fetal growth restriction (FGR) caused by placental insufficiency is a major contributor to neonatal morbidity and mortality. There is currently no in utero treatment for placental insufficiency or FGR. The placenta serves as the vital communication, supply, exchange, and defense organ for the developing fetus and offers an excellent opportunity for therapeutic interventions. Here we show efficacy of repeated treatments of trophoblast-specific human insulin-like 1 growth factor ( IGF1 ) gene therapy delivered in a non-viral, polymer nanoparticle to the placenta for the treatment of FGR...
April 10, 2024: bioRxiv
https://read.qxmd.com/read/38645135/study-protocol-exploring-the-use-of-family-health-histories-in-the-african-american-community-to-reduce-health-disparities-in-flint-michigan
#35
Kent D Key, Lena Lewis, Courtney Blanchard, Alla Sikorskii, Minal Patel, Todd Lucas, Tabia Henry Akintobi, Sarah Bailey, E Hill Loney, Jennifer E Johnson
Background Health disparities are costly and preventable differences in disease progression that disproportionately affect minority communities such as African Americans. Practices to reduce health disparities can be rooted in prevention, particularly through screening tools. Family Health History tools are preventative screening mechanisms meant to explore family history to better understand how an individual's health can potentially be predicted or impacted. These tools are underutilized in the African American community...
April 1, 2024: Research Square
https://read.qxmd.com/read/38644971/one-health-intervention-for-elimination-of-anthrax-in-an-endemic-district-of-odisha-a-baseline-and-endline-study
#36
JOURNAL ARTICLE
Matrujyoti Pattnaik, Hari Ram Choudhary, Debaprasad Parai, Jyoti Shandilya, Arun Kumar Padhi, Niranjana Sahoo, Shishirendu Ghosal, Sarangdhar Sathpathy, Santosh Kumar Panigrahi, Susanta Kumar Sahu, Aurobindo Samantaray, Sanghamitra Pati, Debdutta Bhattacharya
BACKGROUND: This study was to compare a baseline and endline survey which were conducted to assess the changes in knowledge, attitude and practices about anthrax disease among the communities after One Health intervention for the elimination of human anthrax in an endemic district of Odisha. METHODS: A total of 2670 respondents were interviewed during the baseline and 2511 for the endline survey using a structured questionnaire by multi-stage sampling method. Descriptive statistics were used and logistic regression was performed to estimate the relationship between the variables and knowledge of anthrax...
June 2024: One Health
https://read.qxmd.com/read/38644879/internet-addiction-of-university-students-in-the-covid-19-process
#37
JOURNAL ARTICLE
İsmail Şan, Hanife Gülhan Orhan Karsak, Eyüp İzci, Kübra Öncül
This study delves into the intricate dynamics of internet addiction among university students, leveraging a comprehensive quantitative approach to unravel the myriad factors influencing this modern-day malaise. Utilizing logistic regression analysis, this research delineates the predictive significance of Daily Internet Usage Time (DIUT) and Communicative Internet Use Frequency (CIUF) on the propensity for internet addiction, with the analysis substantiating these variables as potent predictors. The model elucidates a significant variance in internet addiction, affirming the complexity of internet addiction as influenced by a constellation of behavioral patterns...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38644596/impact-of-sociodemographic-factors-stress-and-communication-on-health-related-quality-of-life-in-survivors-of-pediatric-cancer
#38
JOURNAL ARTICLE
Valdeoso Patterson, Anna Olsavsky, Dana Garcia, Malcolm Sutherland-Foggio, Kathryn Vannatta, Kemar V Prussien, Heather Bemis, Bruce E Compas, Cynthia A Gerhardt
BACKGROUND: While most research has largely focused on medical risks associated with reduced health-related quality of life (HRQOL) in survivors, sociodemographic and family factors may also play a role. Thus, we longitudinally examined sociodemographic factors and family factors associated with survivor HRQOL, including adolescent's cancer-specific stress, mother's general stress, and mother-adolescent communication. METHODS: Mothers (N = 80) and survivors (ages 10-23, N = 50) were assessed 5 years following initial diagnosis...
April 21, 2024: Pediatric Blood & Cancer
https://read.qxmd.com/read/38644476/exploring-variations-in-ipc-competencies-a-cross-sectional-study-among-healthcare-professionals-in-northwest-china
#39
JOURNAL ARTICLE
Qinglan Zhao, Xiaoqing Cui, Ting Liu, Hanxue Li, Miaoyue Shi, Li Wang
BACKGROUND: This cross-sectional study investigates infection prevention and control (IPC) competencies among healthcare professionals in northwest China, examining the influence of demographic factors, job titles, education, work experience, and hospital levels. METHODS: Data from 874 respondents across 47 hospitals were collected through surveys assessing 16 major IPC domains. Statistical analyses, including Mann-Whitney tests, were employed to compare competencies across variables...
April 22, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38644472/exosomal-mediators-in-sepsis-and-inflammatory-organ-injury-unraveling-the-role-of-exosomes-in-intercellular-crosstalk-and-organ-dysfunction
#40
REVIEW
Ting Gong, You-Tan Liu, Jie Fan
Sepsis, a severe systemic inflammatory response to infection, remains a leading cause of morbidity and mortality worldwide. Exosomes, as mediators of intercellular communication, play a pivotal role in the pathogenesis of sepsis through modulating immune responses, metabolic reprogramming, coagulopathy, and organ dysfunction. This review highlights the emerging significance of exosomes in these processes. Initially, it provides an in-depth insight into exosome biogenesis and characterization, laying the groundwork for understanding their diverse and intricate functions...
April 22, 2024: Military Medical Research
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