Seyyed Ali Hosseini, Isaac Shiri, Pardis Ghaffarian, Ghasem Hajianfar, Atlas Haddadi Avval, Milad Seyfi, Stijn Servaes, Pedro Rosa-Neto, Habib Zaidi, Mohammad Reza Ay
PURPOSE: This study aimed to examine the robustness of positron emission tomography (PET) radiomic features extracted via different segmentation methods before and after ComBat harmonization in patients with non-small cell lung cancer (NSCLC). METHODS: We included 120 patients (positive recurrence = 46 and negative recurrence = 74) referred for PET scanning as a routine part of their care. All patients had a biopsy-proven NSCLC. Nine segmentation methods were applied to each image, including manual delineation, K-means (KM), watershed, fuzzy-C-mean, region-growing, local active contour (LAC), and iterative thresholding (IT) with 40, 45, and 50% thresholds...
April 4, 2024: Annals of Nuclear Medicine