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Contouring radiotherapy

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https://www.readbyqxmd.com/read/28811150/best-practice-recommendations-for-the-retention-of-radiotherapy-records
#1
E Lockhart, K Bak, L J Schreiner, D C Hodgson, E Gutierrez, P Warde, M B Sharpe
This paper offers best practice recommendations for the maintenance and retention of radiotherapy health records and technical information for cancer programmes. The recommendations are based on a review of the published and grey literature, feedback from key informants from seven countries and expert consensus. Ideally, complete health records should be retained for 5 years beyond the patient's lifetime, regardless of where they are created and maintained. Technical information constituting the radiotherapy plan should also be retained beyond the patient's lifetime for 5 years, including the primary images, contours of delineated targets and critical organs, dose distributions and other radiotherapy plan objects...
August 12, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28797999/long-term-results-of-post-operative-pelvic-image-guided-intensity-modulated-radiotherapy-in-gynecological-malignancies
#2
Rashi Agrawal, Sowmiya Prithiviraj, Dinesh Singh, Vaishali Zamre, Sandeep Agrawal, Arun Kumar Goel, Kanika Gupta, Bala Subramanian
OBJECTIVE: To assess late clinical outcomes with image guided intensity modulated radiotherapy (IG- IMRT) in gynecological malignancies. PATIENTS AND METHODS: We have been practicing IG IMRT for gynecological malignancies since January 2009. Here we are presenting our experience with this modern technique at median follow up of 38 months. During whole treatment bladder filling protocol was followed. Both target volumes and critical structures were contoured according to RTOG guidelines...
May 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28797587/subcutaneous-adipose-tissue-characteristics-and-the-risk-of-biochemical-recurrence-in-men-with-high-risk-prostate-cancer
#3
Andrew M McDonald, John B Fiveash, Robert S Kirkland, Rex A Cardan, Rojymon Jacob, Robert Y Kim, Michael C Dobelbower, Eddy S Yang
PURPOSE/OBJECTIVE(S): To assess subcutaneous adipose tissue characteristics by computed tomography (CT) as potential imaging biomarkers predictive of biochemical recurrence in men with high-risk prostate cancer receiving radiotherapy (RT). MATERIALS AND METHODS: This retrospective study included men with high-risk prostate cancer (PSA>20ng/ml, Gleason score ≥8, or clinical extraprostatic extension) treated between 2001 and 2012. All patients received definitive, dose-escalated external beam RT along with a course of neoadjuvant, concurrent, and adjuvant androgen deprivation therapy (ADT)...
August 7, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28781156/evaluation-of-deformed-image-based-dose-calculations-for-adaptive-radiotherapy-of-nasopharyngeal-carcinoma
#4
Miranda Poon, Catherine Holborn, Ka Fai Cheng, Winky Wing Ki Fung, George Chiu
The ultimate goal of adaptive radiotherapy (ART) is to deliver truly customized radiation treatments. Currently, the quality of cone-beam computed tomography (CBCT) images is still inferior to that of conventional CT images in contour delineations and dose calculations for replanning purposes. This retrospective study aims to evaluate the dosimetric accuracy of using deformed conventional CT images for dose calculations, in the hope of inferring the feasibility of ART using planning CT (PCT) images that deformed to up-to-date CBCT images for patients with nasopharyngeal carcinoma (NPC)...
August 3, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28774489/-normal-tissue-tolerance-to-external-beam-radiation-therapy-bone-marrow-and-cortical-bone-structures
#5
A Schernberg, C Hennequin
In patients undergoing external radiation therapy, bone marrow and cortical bone structures are all often neglected as organs at risk. Still, from increased febrile neutropenia risk in patients undergoing chemoradiation for a pelvic tumour to increased risk of vertebral fracture when undergoing hypofractioned stereotactic radiotherapy of a spinal metastasis, adverse effects are frequent and sometimes serious. This literature review first defines the rules for contouring these structures, then the dose constraints currently recommended...
July 31, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28762462/radiation-induced-neurocognitive-dysfunction-in-head-and-neck-cancer-patients
#6
Francesca De Felice, Pierre Blanchard
It might seem odd that a special issue about Gianni Bonadonna would publish a review on radiation-induced neurocognitive dysfunction. Dr. Gianni Bonadonna is considered a pioneer in medical oncology history, mainly due to new and revolutionary treatment approaches proposed in breast cancer and Hodgkin lymphoma. He had an active role in the field of medical oncology, especially through lectures and textbooks. He shared his considerable insight of understanding cancer behavior and evaluating research advances over the years to prevent tumor recurrence and preserve patients from unnecessary toxicity...
July 31, 2017: Tumori
https://www.readbyqxmd.com/read/28740459/dosimetric-predictors-of-treatment-related-lymphopenia-induced-by-palliative-radiotherapy-predictive-ability-of-dose-volume-parameters-based-on-body-surface-contour
#7
Tetsuo Saito, Ryo Toya, Tomohiko Matsuyama, Akiko Semba, Natsuo Oya
BACKGROUND: Radiation-related lymphopenia has been associated with poor patient outcome. Our aim was to identify predictors of lymphopenia after palliative radiotherapy, with a focus on dose-volume parameters. PATIENTS AND METHODS: To retrospectively assess patients with various cancers who had undergone palliative radiotherapy, we delineated three organs at risk: the volume enclosed by the body surface contour (body A), the volume left after excluding air, pleural effusion, ascites, bile, urine, and intestinal content (body B), and the volume of the bone marrow (BM)...
June 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/28740451/mri-reduces-variation-of-contouring-for-boost-clinical-target-volume-in-breast-cancer-patients-without-surgical-clips-in-the-tumour-bed
#8
Noora Al-Hammadi, Palmira Caparrotti, Saju Divakar, Mohamed Riyas, Suparna Halsnad Chandramouli, Rabih Hammoud, Jillian Hayes, Maeve Mc Garry, Satheesh Prasad Paloor, Primoz Petric
BACKGROUND: Omitting the placement of clips inside tumour bed during breast cancer surgery poses a challenge for delineation of lumpectomy cavity clinical target volume (CTVLC). We aimed to quantify inter-observer variation and accuracy for CT- and MRI-based segmentation of CTVLC in patients without clips. PATIENTS AND METHODS: CT- and MRI-simulator images of 12 breast cancer patients, treated by breast conserving surgery and radiotherapy, were included in this study...
June 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/28727787/feasibility-of-a-3d-printed-anthropomorphic-patient-specific-head-phantom-for-patient-specific-quality-assurance-of-intensity-modulated-radiotherapy
#9
Ji Woon Yea, Jae Won Park, Sung Kyu Kim, Dong Youn Kim, Jae Gu Kim, Chan Young Seo, Won Hyo Jeong, Man Youl Jeong, Se An Oh
This study evaluated the feasibility of utilizing a 3D-printed anthropomorphic patient-specific head phantom for patient-specific quality assurance (QA) in intensity-modulated radiotherapy (IMRT). Contoured left and right head phantoms were converted from DICOM to STL format. Fused deposition modeling (FDM) was used to construct an anthropomorphic patient-specific head phantom with a 3D printer. An established QA technique and the patient-specific head phantom were used to compare the calculated and measured doses...
2017: PloS One
https://www.readbyqxmd.com/read/28716090/clinical-workflow-for-mr-only-simulation-and-planning-in-prostate
#10
Neelam Tyagi, Sandra Fontenla, Michael Zelefsky, Marcia Chong-Ton, Kyle Ostergren, Niral Shah, Lizette Warner, Mo Kadbi, Jim Mechalakos, Margie Hunt
PURPOSE: To describe the details and experience of implementing a MR-only workflow in the clinic for simulation and planning of prostate cancer patients. METHODS: Forty-eight prostate cancer patients from June 2016 - Dec 2016 receiving external beam radiotherapy were scheduled to undergo MR-only simulation. MR images were acquired for contouring (T2w axial, coronal, sagittal), synthetic-CT generation (3D FFE-based) and fiducial identification (3D bFFE-based). The total acquisition time was 25 min...
July 17, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28714458/a-graphical-approach-to-optimizing-variable-kernel-smoothing-parameters-for-improved-deformable-registration-of-ct-and-cone-beam-ct-images
#11
Vern Hart, Damon Burrow, X Allen Li
A systematic method is presented for determining optimal parameters in variable-kernel deformable image registration of cone beam CT and CT images, in order to improve accuracy and convergence for potential use in online adaptive radiotherapy. Assessed conditions included the noise constant (symmetric force demons), the kernel reduction rate, the kernel reduction percentage, and the kernel adjustment criteria. Four such parameters were tested in conjunction with reductions of 5, 10, 15, 20, 30, and 40%. Noise constants ranged from 1...
July 17, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28709427/investigation-of-irradiated-volume-in-linac-based-brain-hypo-fractionated-stereotactic-radiotherapy
#12
Mark Ruschin, Arjun Sahgal, Hany Soliman, Sten Myrehaug, May Tsao, Collins Yeboah, Arman Sarfehnia, Brige Chugh, Alex Kiss, Young Lee
BACKGROUND: Emerging techniques such as brain hypo-fractionated radiotherapy (HF-RT) involve complex cases with limited guidelines for plan quality and normal tissue tolerances. The purpose of the present study was to statistically parameterize irradiated volume independently of dose prescription, or margin to determine what spread in achievable irradiated volume one may expect for a given case. METHODS: We defined EXT as the total tissue within the external contour of the patient (including the target) and we defined BMP as the contour of the brain minus PTV...
July 14, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28674678/tangential-field-radiotherapy-for-breast-cancer-the-dose-to-the-heart-and-heart-subvolumes-what-structures-must-be-contoured-in-future-clinical-trials
#13
Marciana Nona Duma, Anne-Claire Herr, Kai Joachim Borm, Klaus Rüdiger Trott, Michael Molls, Markus Oechsner, Stephanie Elisabeth Combs
BACKGROUND AND PURPOSE: The aim of the present study was to evaluate if it is feasible for experienced radiation oncologists to visually sort out patients with a large dose to the heart. This would facilitate large retrospective data evaluations. And in case of an insufficient visual assessment, to define which structures should be contoured and which structures can be skipped as their dose can be derived from other easily contoured structures for future clinical trials. MATERIAL AND METHODS: Planning CTs of left-sided breast cancer patients treated with 3D-conformal radiotherapy by tangential fields were visually divided into two groups: with an estimated high dose (HiD) and with an estimated low dose (LoD) to the heart...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28661100/estimation-of-lung-tumor-position-from-multiple-anatomical-features-on-4d-ct-using-multiple-regression-analysis
#14
Tomohiro Ono, Mitsuhiro Nakamura, Yoshinori Hirose, Kenji Kitsuda, Yuka Ono, Takashi Ishigaki, Masahiro Hiraoka
To estimate the lung tumor position from multiple anatomical features on four-dimensional computed tomography (4D-CT) data sets using single regression analysis (SRA) and multiple regression analysis (MRA) approach and evaluate an impact of the approach on internal target volume (ITV) for stereotactic body radiotherapy (SBRT) of the lung. Eleven consecutive lung cancer patients (12 cases) underwent 4D-CT scanning. The three-dimensional (3D) lung tumor motion exceeded 5 mm. The 3D tumor position and anatomical features, including lung volume, diaphragm, abdominal wall, and chest wall positions, were measured on 4D-CT images...
June 29, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28660217/a-prospective-study-comparing-functional-imaging-18-f-fdg-pet-versus-anatomical-imaging-contrast-enhanced-ct-in-dosimetric-planning-for-non-small-cell-lung-cancer
#15
Archana Prathipati, Ranadheer Gupta Manthri, Bala Venkat Subramanian, Pranabandhu Das, Swapna Jilla, Sangeetha Mani, Anitha Kumari J, Settipalli Sarala, Radhika Kottu, Tek Chand Kalawat, Kotiyala Venkata Jagannath Rao Naidu
OBJECTIVES: (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET-CT) is a well-used and established technique for lung cancer staging. Radiation therapy requires accurate target volume delineation, which is difficult in most cases due to coexisting atelectasis. The present study was performed to compare the (18)F-FDG PET-CT with contrast enhanced computed tomography (CECT) in target volume delineation and investigate their impacts on radiotherapy planning...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/28646463/patterns-of-failure-after-radical-prostatectomy-in-prostate-cancer-implications-for-radiation-therapy-planning-after-68-ga-psma-pet-imaging
#16
Kilian Schiller, K Sauter, S Dewes, M Eiber, T Maurer, J Gschwend, S E Combs, G Habl
BACKGROUND: Salvage radiotherapy (SRT) after radical prostatectomy (RPE) and lymphadenectomy (LAE) is the appropriate radiotherapy option for patients with persistent/ recurrent prostate cancer (PC). (68)Ga-PSMA-PET imaging has been shown to accurately detect PC lesions in a primary setting as well as for local recurrence or for lymph node (LN) metastases. OBJECTIVE: In this study we evaluated the patterns of recurrence after RPE in patients with PC, putting a highlight on the differentiation between sites that would have been covered by a standard radiation therapy (RT) field in consensus after the RTOG consensus and others that would have not...
September 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28633674/primary-tumor-volume-delineation-in-head-and-neck-cancer-missing-the-tip-of-the-iceberg
#17
Olgun Elicin, Dario Terribilini, Mohamed Shelan, Werner Volken, Etienne Mathier, Alan Dal Pra, Daniel M Aebersold, Michael K Fix, Peter Manser
BACKGROUND: The aim was to evaluate the geometric and corresponding dosimetric differences between two delineation strategies for head and neck tumors neighboring air cavities. METHODS: Primary gross and clinical tumor volumes (GTV and CTV) of 14 patients with oropharynx or larynx tumors were contoured using a soft tissue window (S). In a second strategy, the same volumes were contoured with an extension to include the parts which became visible on lung window (L)...
June 20, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28626489/conference-report-on-the-indo-global-summit-on-head-and-neck-oncology-igshno-2017-bmcon-iv-24-26-february-2017-jaipur-india
#18
Tej Prakash Soni, Anil K Gupta, Lalit M Sharma, Pawan Singhal, Dinesh Yadav, Umesh Bansal
'The multidisciplinary approach: expanding treatment horizons for head and neck cancer' was the major theme of the Indo Global Summit on Head and Neck Oncology (IGSHNO 2017-BMCON-IV). The meeting, held in Jaipur (Rajasthan, India) from 24 to 26 February 2017, assembled 600 participants from India and worldwide. It was organised by the Bhagwan Mahaveer Cancer Hospital and Research Centre (BMCHRC), Jaipur. BMCHRC Jaipur is one of the largest superspeciality oncology research and treatment centres in north India...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28624714/patient-reported-outcomes-of-autologous-fat-grafting-after-breast-cancer-surgery
#19
A W W Brown, M Kabir, K A Sherman, F Meybodi, J R French, E B Elder
INTRODUCTION: Autologous fat grafting (AFG) can be used as an adjunct in breast cancer surgery to improve contour defects. Few previous studies have assessed patient reported outcomes (PROs) for AFG. This study analysed AFG use and assessed PROs in terms of physical and psychosocial well-being. MATERIALS AND METHODS: All patients undergoing AFG were identified from a prospective database and asked to complete the validated BREAST-Q questionnaire and a tool to assess patient-perceived change after AFG (5-point Likert-type scale)...
June 15, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28623847/toxicity-after-post-prostatectomy-image-guided-intensity-modulated-radiotherapy-using-australian-guidelines
#20
Stephen Chin, Noel J Aherne, Andrew Last, Hassan Assareh, Thomas P Shakespeare
INTRODUCTION: We evaluated single institution toxicity outcomes after post-prostatectomy radiotherapy (PPRT) via image-guided intensity-modulated radiation therapy (IG-IMRT) with implanted fiducial markers following national eviQ guidelines, for which late toxicity outcomes have not been published. METHODS: Prospectively collected toxicity data were retrospectively reviewed for 293 men who underwent 64-66 Gy IG-IMRT to the prostate bed between 2007 and 2015. RESULTS: Median follow-up after PPRT was 39 months...
June 17, 2017: Journal of Medical Imaging and Radiation Oncology
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