keyword
MENU ▼
Read by QxMD icon Read
search

Delineation

keyword
https://www.readbyqxmd.com/read/28231633/barriers-to-regaining-control-within-a-constructivist-grounded-theory-of-family-resilience-in-icu-living-with-uncertainty
#1
Pauline Wong, Pranee Liamputtong, Susan Koch, Helen Rawson
This paper discusses families' experiences of their interactions when a relative is admitted unexpectedly to an Australian intensive care unit BACKGROUND: The overwhelming emotions associated with the unexpected admission of a relative to an intensive care unit (ICU) are often due to the uncertainty surrounding the condition of their critically ill relative. There is limited in-depth understanding of the nature of uncertainty experienced by families in ICU, and interventions perceived by families to minimise their uncertainty are not well documented...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231407/co-occurrence-and-hybridization-of-anther-smut-pathogens-specialized-on-dianthus-hosts
#2
Elsa Petit, Casey Silver, Amandine Cornille, Pierre Gladieux, Lisa Rosenthal, Emily Bruns, Sarah Yee, Janis Antonovics, Tatiana Giraud, Michael E Hood
Host specialization has important consequences for the diversification and ecological interactions of obligate pathogens. The anther-smut disease of natural plant populations, caused by Microbotryum fungi, has been characterized by specialized host-pathogen interactions, which contribute in part to the isolation among these numerous fungal species. This study investigated the molecular variation of Microbotryum pathogens within the geographic and host-specific distributions on wild Dianthus species in southern European Alps...
February 23, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28231309/improving-molecular-diagnosis-of-aniridia-and-wagr-syndrome-using-customized-targeted-array-based-cgh
#3
Fiona Blanco-Kelly, María Palomares, Elena Vallespín, Cristina Villaverde, Rubén Martín-Arenas, Camilo Vélez-Monsalve, Isabel Lorda-Sánchez, Julián Nevado, María José Trujillo-Tiebas, Pablo Lapunzina, Carmen Ayuso, Marta Corton
Chromosomal deletions at 11p13 are a frequent cause of congenital Aniridia, a rare pan-ocular genetic disease, and of WAGR syndrome, accounting up to 30% of cases. First-tier genetic testing for newborn with aniridia, to detect 11p13 rearrangements, includes Multiplex Ligation-dependent Probe Amplification (MLPA) and karyotyping. However, neither of these approaches allow obtaining a complete picture of the high complexity of chromosomal deletions and breakpoints in aniridia. Here, we report the development and validation of a customized targeted array-based comparative genomic hybridization, so called WAGR-array, for comprehensive high-resolution analysis of CNV in the WAGR locus...
2017: PloS One
https://www.readbyqxmd.com/read/28230766/extraction-and-identification-of-phlorotannins-from-the-brown-alga-sargassum-fusiforme-harvey-setchell
#4
Yajing Li, Xiaoting Fu, Delin Duan, Xiaoyong Liu, Jiachao Xu, Xin Gao
Phlorotannins are a group of complex polymers of phloroglucinol (1,3,5-trihydroxybenzene), which are unique compounds from marine brown algae. In our present study, a procedure for extraction and enrichment of phlorotannins from S. fusiforme with highly antioxidant potentials was established. After comparison of different extraction methods, the optimal extraction conditions were established as follows. The freeze-dried seaweed powder was extracted with 30% ethanol-water solvent with a solid/liquid ratio of 1:5 at temperature of 25 °C for 30 min...
February 21, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28230104/long-term-impact-of-temporal-sequence-from-childhood-obesity-to-hyperinsulinemia-on-adult-metabolic-syndrome-and-diabetes-the-bogalusa-heart-study
#5
Tao Zhang, Huijie Zhang, Ying Li, Shengxu Li, Camilo Fernandez, Lydia Bazzano, Jiang He, Fuzhong Xue, Wei Chen
This study aims to delineate the temporal relations between body mass index (BMI) and insulin in childhood and their impact on adult metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM).The longitudinal cohort consisted of 609 whites and 339 blacks who had BMI and fasting insulin measured twice in childhood (mean age = 10.5 years at baseline and 15.9 years at follow-up). Incident MetS and T2DM were identified in adulthood (mean age = 30.5 years). Cross-lagged panel and mediation analysis models were used...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28230048/differential-regulation-of-the-epr3-receptor-coordinates-membrane-restricted-rhizobial-colonization-of-root-nodule-primordia
#6
Yasuyuki Kawaharada, Mette W Nielsen, Simon Kelly, Euan K James, Kasper R Andersen, Sheena R Rasmussen, Winnie Füchtbauer, Lene H Madsen, Anne B Heckmann, Simona Radutoiu, Jens Stougaard
In Lotus japonicus, a LysM receptor kinase, EPR3, distinguishes compatible and incompatible rhizobial exopolysaccharides at the epidermis. However, the role of this recognition system in bacterial colonization of the root interior is unknown. Here we show that EPR3 advances the intracellular infection mechanism that mediates infection thread invasion of the root cortex and nodule primordia. At the cellular level, Epr3 expression delineates progression of infection threads into nodule primordia and cortical infection thread formation is impaired in epr3 mutants...
February 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28229910/optimized-energy-of-spectral-ct-for-infarct-imaging-experimental-validation-with-human-validation
#7
Veit Sandfort, Srikanth Palanisamy, Rolf Symons, Amir Pourmorteza, Mark A Ahlman, Kelly Rice, Tom Thomas, Cynthia Davies-Venn, Bernhard Krauss, Alan Kwan, Ankur Pandey, Stefan L Zimmerman, David A Bluemke
OBJECTIVES: Late contrast enhancement visualizes myocardial infarction, but the contrast to noise ratio (CNR) is low using conventional CT. The aim of this study was to determine if spectral CT can improve imaging of myocardial infarction. MATERIALS AND METHODS: A canine model of myocardial infarction was produced in 8 animals (90-min occlusion, reperfusion). Later, imaging was performed after contrast injection using CT at 90 kVp/150 kVpSn. The following reconstructions were evaluated: Single energy 90 kVp, mixed, iodine map, multiple monoenergetic conventional and monoenergetic noise optimized reconstructions...
February 11, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28229821/integration-of-capillary-microscopy-and-dermoscopy-into-the-rheumatology-fellow-curriculum
#8
Christopher Hatzis, Daniele Lerner, Stephen Paget, Maurizio Cutolo, Vanessa Smith, Robert Spiera, Jessica Gordon
OBJECTIVES: This study evaluates a novel, three-part nailfold capillaroscopy training curriculum for adult and paediatric rheumatology fellows. METHODS: All rheumatology fellows training at an academic medical centre took part in the three-part nailfold capillaroscopy curriculum. Tests of fellows' usage, interest, confidence, and ability in nailfold capillaroscopy were taken at multiple time-points throughout the curriculum. RESULTS: Fellows self-reported high levels of interest, increased confidence in delineating normal and abnormal nailfold capillaries (p=0...
February 10, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28229505/a-variant-in-a-cis-regulatory-element-enhances-claudin-14-expression-and-is-associated-with-pediatric-onset-hypercalciuria-and-kidney-stones
#9
Megan E Ure, Emma Heydari, Wanling Pan, Ajay Ramesh, Sabah Rehman, Catherine Morgan, Maury Pinsk, Robin Erickson, Johannes M Herrmann, Henrik Dimke, Emmanuelle Cordat, Mathieu Lemaire, Michael Walter, R Todd Alexander
The greatest risk factor for kidney stones is hypercalciuria, the etiology of which is largely unknown. A recent genome-wide association study (GWAS) linked hypercalciuria and kidney stones to a claudin-14 (CLDN14) risk haplotype. However, the underlying molecular mechanism was not delineated. Recently, renal CLDN14 expression was found to increase in response to increased plasma calcium, thereby inducing calciuria. We hypothesized therefore that some children with hypercalciuria and kidney stones harbor a CLDN14 variant that inappropriately increases gene expression...
February 22, 2017: Human Mutation
https://www.readbyqxmd.com/read/28229223/levodopa-carbidopa-intestinal-gel-lcig-infusion-as-mono-or-combination-therapy
#10
Carsten Buhmann, R Hilker, P Lingor, C Schrader, J Schwarz, M Wolz, H Reichmann
Levodopa/carbidopa intestinal gel (LCIG) infusion is an effective escalating therapy in patients with Parkinson disease (PD) suffering from motor fluctuations and dyskinesia. Levodopa/carbidopa given continuously as infusion provides an optimized application of the most effective and best tolerable antiparkinsonian drug. It has been proven to have a superior motor effect compared with oral levodopa and to improve also non-motor symptoms. However, invasiveness, discomfort resulting from carrying an external device, and side effects associated with the way of administration limit its application in PD patients...
February 22, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28229077/surgical-therapy-of-cholangiocarcinoma
#11
REVIEW
Arnold Radtke, Alfred Königsrainer
BACKGROUND: The majority of patients with cholangiocarcinoma present with advanced disease that is often challenging to diagnose and to treat. The optimal preoperative evaluation requires a coordinated multidisciplinary approach. Surgical resection is the mainstay of therapy. METHODS: This systematic review delineates surgical treatment strategies for cholangiocarcinoma in general as well as special considerations concerning the particular tumor localization. A literature search (see keywords) was conducted using PubMed and publications between 1990 and 2016 regarding resectable and advanced cholangiocarcinoma were reviewed...
December 2016: Visceral Medicine
https://www.readbyqxmd.com/read/28228768/genome-wide-single-nucleotide-polymorphisms-in-cms-and-restorer-lines-discovered-by-genotyping-using-sequencing-and-association-with-marker-combining-ability-for-12-yield-related-traits-in-oryza-sativa-l-subsp-japonica
#12
Imdad U Zaid, Weijie Tang, Erbao Liu, Sana U Khan, Hui Wang, Edzesi W Mawuli, Delin Hong
Heterosis or hybrid vigor is closely related with general combing ability (GCA) of parents and special combining ability (SCA) of combinations. The evaluation of GCA and SCA facilitate selection of parents and combinations in heterosis breeding. In order to improve combining ability (CA) by molecular marker assist selection, it is necessary to identify marker loci associated with the CA. To identify the single nucleotide polymorphisms (SNP) loci associated with CA in the parental genomes of japonica rice, genome-wide discovered SNP loci were tested for association with the CA of 18 parents for 12 yield-related traits...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28228108/expression-profiling-and-bioinformatic-analyses-suggest-new-target-genes-and-pathways-for-human-hair-follicle-related-micrornas
#13
Lara M Hochfeld, Thomas Anhalt, Céline S Reinbold, Marisol Herrera-Rivero, Nadine Fricker, Markus M Nöthen, Stefanie Heilmann-Heimbach
BACKGROUND: Human hair follicle (HF) cycling is characterised by the tight orchestration and regulation of signalling cascades. Research shows that micro(mi)RNAs are potent regulators of these pathways. However, knowledge of the expression of miRNAs and their target genes and pathways in the human HF is limited. The objective of this study was to improve understanding of the role of miRNAs and their regulatory interactions in the human HF. METHODS: Expression levels of ten candidate miRNAs with reported functions in hair biology were assessed in HFs from 25 healthy male donors...
February 22, 2017: BMC Dermatology
https://www.readbyqxmd.com/read/28227420/automated-in-vivo-delineation-of-lumen-wall-using-intravascular-ultrasound-imaging
#14
Debarghya China, Manas K Nag, K M Mandana, Anup K Sadhu, Pabitra Mitra, Chandan Chakraborty, Debarghya China, Manas K Nag, K M Mandana, Anup K Sadhu, Pabitra Mitra, Chandan Chakraborty, Chandan Chakraborty, Manas K Nag, Debarghya China, Pabitra Mitra, Anup K Sadhu, K M Mandana
This paper presents a novel methodology for automated detection and extraction of the lumen wall from Intravascular Ultrasound (IVUS) frames. IVUS is an in-vivo pull back imaging technique and provides a sequential frame of images for diagnosis of atherosclerotic heart disease. The detection and segmentation of lumen wall is necessary for predicting the arterial wall blockage. Lumen wall is recognized and segmented with the help of seed refinement and random walks algorithms, in tunica and lumen area. The proposed methodology was tested on 147 frames of 13 patients...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227405/template-based-rodent-brain-extraction-and-atlas-mapping
#15
Weimin Huang, Jiaqi Zhang, Zhiping Lin, Su Huang, Yuping Duan, Zhongkang Lu, Weimin Huang, Jiaqi Zhang, Zhiping Lin, Su Huang, Yuping Duan, Zhongkang Lu, Jiaqi Zhang, Weimin Huang, Yuping Duan, Zhongkang Lu, Zhiping Lin, Su Huang
Accurate rodent brain extraction is the basic step for many translational studies using MR imaging. This paper presents a template based approach with multi-expert refinement to automatic rodent brain extraction. We first build the brain appearance model based on the learning exemplars. Together with the template matching, we encode the rodent brain position into the search space to reliably locate the rodent brain and estimate the rough segmentation. With the initial mask, a level-set segmentation and a mask-based template learning are implemented further to the brain region...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227388/learning-to-distinguish-cerebral-vasculature-data-from-mechanical-chatter-in-india-ink-images-acquired-using-knife-edge-scanning-microscopy
#16
Michael R Nowak, Yoonsuck Choe, Michael R Nowak, Yoonsuck Choe, Michael R Nowak, Yoonsuck Choe
We introduce a simple, yet effective, procedure for accurate classification of connected components embedded in biological images. In our method, a training set is generated from user-delineated features of manually-labeled examples; we subsequently train a classifier using the resultant training set. The overall process is described using imaging data acquired from an India-ink perfused C57BL/6J mouse brain using Knife Edge Scanning Microscopy. We illustrate the procedure through segmentation of cerebral vasculature structures from mechanical noise using trained classifiers...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227346/respiratory-rate-estimation-from-multilead-directions-based-on-ecg-delineation
#17
M Noriega, E J Maranon, D Romero, M Orini, R Almeida, M Noriega, E J Maranon, D Romero, M Orini, R Almeida, M Orini, M Noriega, R Almeida, D Romero, E J Maranon
Estimating the instantaneous respiratory rate (Rr) from the electrocardiogram (ECG) is of interest as respiration direct measurement in clinical situations is often cumbersome. In this study, the Rr was estimated from the same Final Directions of maximum projection (FD) used for multi lead ECG automatic delineation. Power spectral analysis over the directions based on QRS complex main peak and T wave onset, peak and end spatial loops was used for Rr estimation. On a subset of the Physionet MGH/MF dataset, the proposed method yielded more accurate Rr estimates (minimum mean absolute error (MAE), 2...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227343/application-of-a-new-robust-ecg-t-wave-delineation-algorithm-for-the-evaluation-of-the-autonomic-innervation-of-the-myocardium
#18
Matteo Cesari, Jesper Mehlsen, Anne-Birgitte Mehlsen, Helge Bjarup Dissing Sorensen, Matteo Cesari, Jesper Mehlsen, Anne-Birgitte Mehlsen, Helge Bjarup Dissing Sorensen, Jesper Mehlsen, Helge Bjarup Dissing Sorensen, Matteo Cesari, Anne-Birgitte Mehlsen
T-wave amplitude (TWA) is a well know index of the autonomic innervation of the myocardium. However, until now it has been evaluated only manually or with simple and inefficient algorithms. In this paper, we developed a new robust single-lead electrocardiogram (ECG) T-wave delineation algorithm that is able to detect the T-wave with a wavelet based method and automatically calculate the TWA. We evaluated the algorithm on the QT database, achieving a sensitivity of 99.92% for the T wave peak and 99.38% for the T wave end...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227014/random-forests-to-predict-tumor-recurrence-following-cervical-cancer-therapy-using-pre-and-per-treatment-18-f-fdg-pet-parameters
#19
Geoffrey Roman-Jimenez, Oscar Acosta, Julie Leseur, Anne Devillers, Henri Der Sarkissian, Lina Guzman, Eloi'se Grossiord, Juan-David Ospina, Renaud De Crevoisier, Geoffrey Roman-Jimenez, Oscar Acosta, Julie Leseur, Anne Devillers, Henri Der Sarkissian, Lina Guzman, Eloi'se Grossiord, Juan-David Ospina, Renaud De Crevoisier, Oscar Acosta, Julie Leseur, Juan-David Ospina, Geoffrey Roman-Jimenez, Henri Der Sarkissian, Renaud De Crevoisier, Anne Devillers, Eloise Grossiord, Lina Guzman
The ability to predict tumor recurrence after chemoradiotherapy of locally advanced cervical cancer is a crucial clinical issue to intensify the treatment of the most high-risk patients. The objective of this study was to investigate tumor metabolism characteristics extracted from pre- and per-treatment (18)F-FDG PET images to predict 3-year overall recurrence (OR). A total of 53 locally advanced cervical cancer patients underwent pre- and per-treatment (18)F-FDG PET (respectively PET1 and PET2). Tumor metabolism was characterized through several delineations using different thresholds, based on a percentage of the maximum uptake, and applied by region-growing...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226737/4d-lung-tumor-segmentation-via-shape-prior-and-motion-cues
#20
Jung Won Cha, Mohammad M Farhangi, Neal Dunlap, Amir Amini, Jung Won Cha, Mohammad M Farhangi, Neal Dunlap, Amir Amini, Jung Won Cha, Amir Amini, Neal Dunlap, Mohammad M Farhangi
Lung tumor segmentation is important for therapy in the radiation treatment of patients with thoracic malignancies. In this paper, we describe a 4D image segmentation method based on graph-cuts optimization, shape prior and optical flow. Due to small size, the location, and low contrast between the tumor and the surrounding tissue, tumor segmentation in 3D+t is challenging. We performed 4D lung tumor segmentation in 5 patients, and in each case compared the results with the expert-delineated lung nodules. In each case, 4D image segmentation took approximately ten minutes on a PC with AMD Phenom II and 32GB of memory for segmenting tumor in five phases of lung CT data...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
keyword
keyword
90454
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"