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https://www.readbyqxmd.com/read/28639336/classification-of-pancreaticobiliary-maljunction-and-clinical-features-in-children
#1
Naoto Urushihara, Yoshinori Hamada, Terumi Kamisawa, Hideki Fujii, Tsugumichi Koshinaga, Yoshiki Morotomi, Takeshi Saito, Takao Itoi, Kenitiro Kaneko, Hiroaki Fukuzawa, Hisami Ando
PURPOSE: In 2015, the Committee on Diagnostic Criteria of the Japanese Study Group on Pancreaticobiliary Maljunction (PBM) proposed a classification of PBM into four types: (A) stenotic type, (B) non-stenotic type, (C) dilated channel type, and (D) complex type. To validate this classification and clarify the clinical features of the four types of PBM, a retrospective multicenter study was conducted. METHODS: We divided the study group of 317 children with PBM into the four types of PBM...
June 21, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28626371/carcinoma-of-the-papilla-of-vater-after-diversion-operation-for-pancreaticobiliary-maljunction
#2
Takahiro Yamanaka, Kenichiro Araki, Norihiro Ishii, Mariko Tsukagoshi, Takamichi Igarashi, Akira Watanabe, Norio Kubo, Hiroyuki Kuwano, Ken Shirabe
Pancreaticobiliary maljunction (PBM) is a congenital malformation that is associated with biliary cancer development. When patients are diagnosed with PBM, a diversion operation is recommended. Although a risk remains for developing residual bile duct carcinoma following diversion, the development of a carcinoma of the ampulla of Vater after a diversion operation for PBM is rare. We present a treated case of carcinoma of the ampulla of Vater after a diversion operation for PBM. A 65-year-old woman presented with abdominal pain...
May 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28622182/reflux-associated-cholecystopathy-analysis-of-76-gallbladders-from-patients-with-supra-oddi-union-of-the-pancreatic-duct-and-common-bile-duct-pancreatobiliary-maljunction-elucidates-a-specific-diagnostic-pattern-of-mucosal-hyperplasia-as-a-prelude-to-carcinoma
#3
Takashi Muraki, Bahar Memis, Michelle D Reid, Takeshi Uehara, Tetsuya Ito, Osamu Hasebe, Shinji Okaniwa, Naoto Horigome, Takeshi Hisa, Pardeep Mittal, Alexa Freedman, Shishir Maithel, Juan M Sarmiento, Alyssa Krasinskas, Jill Koshiol, Volkan Adsay
Pancreaticobiliary maljunction (PBM) is the anomalous union of the main pancreatic duct and common bile duct outside the Oddi-sphincter, allowing the reflux of pancreatic juice to the gallbladder. There is only limited awareness and understanding of the pathologic correlates of this condition, mostly from Japan; this entity is largely unrecognized in the West. In this study, 76 gallbladders from patients with PBM (64 from Japan; 12 from the United States) were analyzed and contrasted with 66 from non-PBM patients...
June 15, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28611338/endoscopic-retrograde-cholangiopancreatography-with-double-balloon-enteroscope-in-patients-with-altered-gastrointestinal-anatomy-a-meta-analysis
#4
REVIEW
Xiao-Dong Shao, Xing-Shun Qi, Xiao-Zhong Guo
BACKGROUND/AIMS: The aim of this study was to evaluate the effectiveness and safety of endoscopic retrograde cholangiopancreatography with double balloon enteroscope (DBE-ERCP) in patients with altered gastrointestinal anatomy in a meta-analysis. MATERIALS AND METHODS: A comprehensive literature search was conducted on PubMed, EMBASE, and Cochrane library covering the period from January 2001 to December 2015. Data were selected and abstracted from eligible studies and were pooled using a random-effects model...
May 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28577538/dai-huang-fu-zi-tang-alleviates-pulmonary-and-intestinal-injury-with-severe-acute-pancreatitis-via-regulating-aquaporins-in-rats
#5
Xin Kang, Xiao-Guang Lu, Li-Bin Zhan, Zheng-Kai Liang, Wen-Xiu Guo, Qi Ma, Yi Wang, Jian-Bo Song, Jin-Yu Feng, Cong-Han Wang, Li-Zhi Bai, Yi Song, Guo-Hui Liu
BACKGROUND: Dai-Huang-Fu-Zi-Tang (DHFZT) is a famous traditional Chinese prescription with intestinal obstruction, acute pancreatitis and cholecystalgia for thousands of years. Our previous work found that DHFZT could act against pulmonary and intestinal pathological injury in rats with severe acute pancreatitis (SAP). But the underlying mechanism has not been fully elucidated. The aim of present study was to investigate whether DHFZT could relieve pulmonary and intestinal injury by regulating aquaporins after SAP induced by sodium taurocholate in rats...
June 2, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28572878/successful-endoscopic-treatment-of-an-intraductal-papillary-neoplasm-of-the-bile-duct
#6
Nikola S Natov, Laura C Horton, Sanjay R Hegde
We present a case of a 76-year-old man with right upper quadrant abdominal pain and weight loss, who was found to have an intraductal papillary neoplasm of the bile duct (IPNB) of the pancreaticobiliary subtype, deemed curatively resectable. The patient declined surgery and opted for endoscopic therapy. He underwent two sessions of endoscopic retrograde cholangiopancreatography (ERCP)-guided radiofrequency ablation (RFA). Ten months later, no evidence of recurrence was identified on repeat ERCP. To our knowledge, this is the first reported case of successful use of RFA as a primary treatment modality for resectable IPNB...
May 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28553687/malignant-mediastinal-lymphadenopathy-detected-by-endoscopic-ultrasound-and-guided-fine-needle-aspiration-in-patients-with-resectable-pancreaticobiliary-cancer
#7
Praveer Rai, Vinod Kumar, Ram Naval Rao
BACKGROUND: Resection surgery for pancreaticobiliary malignancies carries significant morbidity and mortality. Hence, preoperative assessment to exclude unresectable disease is mandatory. CT abdomen is the primary modality for staging of pancreaticobiliary cancers. However, some patients have malignant mediastinal lymphadenopathy (MML), which may be detected on endoscopic ultrasound (EUS) but not on CT scan. METHODS: We prospectively evaluated 75 consecutive patients (median age 54 years: 44 men) with a diagnosis of resectable pancreaticobiliary cancer (carcinoma gallbladder, carcinoma pancreas, cholangiocarcinoma, or periampullary carcinoma) for the presence of MML using EUS by an experienced endosonographer...
May 29, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28551682/surgical-outcomes-of-non-small-cell-lung-cancer-in-patients-with-a-history-of-pancreaticobiliary-cancer
#8
Tetsuzo Tagawa, Kensaku Ito, Kengo Fukuzawa, Tatsuro Okamoto, Atsuro Fujinaga, Takahide Kawasaki, Takashi Masuda, Kentaro Iwaki, Takahiro Terashi, Masahiro Okamoto, Akio Shiromizu, Akira Motohiro, Yoshihiko Maehara
AIM: To determine the efficacy of surgery for non-small cell lung cancer in patients who had previously undergone surgery for pancreaticobiliary cancer. PATIENTS AND METHODS: Seven patients who underwent pulmonary resection for primary lung cancer after curative surgery for pancreaticobiliary cancer at our Institution from 2006 to 2016 were retrospectively evaluated. RESULTS: Five patients had metachronous and two patients had synchronous cancer of pancreaticobiliary and lung origin...
June 2017: Anticancer Research
https://www.readbyqxmd.com/read/28523348/closed-loop-of-main-duct-of-pancreas-a-rare-variant-configuration
#9
Harsimran Jit Singh, Anjali Aggarwal, Rakesh K Kochhar, T D Yadav, Tulika Gupta, Daisy Sahni
During routine dissection, duplication of main pancreatic duct extending from body to head region of pancreas was observed in a 78-year-old formalin fixed male cadaver. Main pancreatic duct gave a prominent branch which joined back the parent duct in head resulting in the formation of a closed loop. This gave the appearance of focal duplication in the form of a closed loop, an unusual variant. This was an incidental finding. Such cases usually remain asymptomatic; however, if undetected may be the cause of postoperative pancreatic fistula following pancreaticobiliary surgery...
May 18, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28496540/recombinant-factor-viia-use-for-endoscopic-retrograde-cholangiopancreatography-with-sphincterotomy-in-a-patient-with-choledocholithiasis-and-unusual-coagulopathy
#10
Molham Abdulsamad, Pavithra Reddy, Suvarna Guvvala, Anil Dev
Endoscopic retrograde cholangiopancreatography (ERCP) is a procedure that combines the use of endoscopy and fluoroscopy to diagnose and treat pancreaticobiliary disorders. The risks of ERCP include pancreatitis, infection, bleeding and perforation. Bleeding during ERCP typically develops after sphincterotomy, hence patients should be screened and tested for coagulopathy before undergoing ERCP. Coagulopathy is a major risk factor for ERCP-related bleeding. Inherited factor VII (FVII) deficiency is a rare autosomal recessive hemorrhagic disorder that can lead to significant coagulopathy and severe bleeding if not appropriately recognized and treated preoperatively...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28474973/hepatic-hilar-lymph-node-reactivity-at-kasai-portoenterostomy-for-biliary-atresia
#11
K E Bove, R Sheridan, L Fei, R Anders, C T Chung, O W Cummings, M J Finegold, L Finn, S Ranganathan, G Kim, M Lovell, M S Magid, H Melin-Aldana, P Russo, B Shehata, L Wang, F White, Z Chen, C Spino, J C Magee
We hypothesized that if infection is the proximate cause of congenital biliary atresia, an appropriate response to antigen would occur in lymph nodes contiguous with the biliary remnant. We compared the number of follicular germinal centers (GC) in 79 surgically excised hilar lymph nodes (LN) and 27 incidentally discovered cystic duct LNs in 84 subjects at the time of hepatic portoenterostomy (HPE) for biliary atresia (BA) to autopsy controls from the pancreaticobiliary region of non-septic infants >3 months old at death...
January 1, 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28415772/endoscopic-therapy-for-patients-with-pancreaticobiliary-maljunction-a-follow-up-study
#12
Zheng Jin, Li-Ke Bie, Yan-Ping Tang, Liang Ge, Si-Si Shen, Bin Xu, Tao Li, Biao Gong
BACKGROUND: Data on the experience of endoscopic retrograde cholangiopancreatography (ERCP) in the management of pancreaticobiliary maljunction (PBM) is limited. METHODS: A retrospective review of patients with PBM who underwent therapeutic ERCP at our endoscopy center between January 2008 and January 2016 was performed. Demographic, clinical, radiological and endoscopic data was documented. Patients who underwent sphincterotomy were divided into dilated group and undilated group base on their common channel diameter...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415560/gallbladder-papillary-neoplasms-share-pathological-features-with-intraductal-papillary-neoplasm-of-the-bile-duct
#13
Xueshuai Wan, Jie Shi, Anqiang Wang, Yuan Xie, Xiaobo Yang, Chengpei Zhu, Haohai Zhang, Liangcai Wu, Shanshan Wang, Hanchun Huang, Jianzhen Lin, Yongchang Zheng, Zhiyong Liang, Xinting Sang, Haitao Zhao
Intraductal papillary neoplasm of the bile duct (IPNB) has been widely recognized. However, the knowledge of intracystic papillary neoplasm of the gallbladder (IPNG) including papillary adenoma and adenocarcinoma is not well defined. In this study, we compared the clinicopathological and immunohistochemical features between 32 IPNG cases and 32 IPNB cases. IPNG-1 (low-high grade dysplasia) exhibited an earlier onset age, smaller tumor size and lower level of CK20 expression compared to IPNG-2 (invasive carcinoma)...
May 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28399609/early-adverse-events-and-long-term-outcomes-of-endoscopic-sphincterotomy-in-a-pediatric-population-a-single-center-experience
#14
Jin Min Cho, In Sook Jeong, Hyun Jin Kim, Seak Hee Oh, Kyung Mo Kim
Background and aims: The use of endoscopic sphincterotomy (EST) in the management of pancreaticobiliary disease in children is increasing. However, studies of long-term outcomes are limited in pediatric patients. Therefore, this study evaluated the early adverse events and long-term outcomes following EST in pediatric patients. Patients and methods: We retrospectively analyzed data from 198 pediatric patients who underwent ESTs at Asan Medical Center Children's Hospital between 1994 and 2013. The median age was 8...
May 2017: Endoscopy
https://www.readbyqxmd.com/read/28393319/the-emerging-role-of-endoscopic-ultrasound-for-pancreaticobiliary-diseases-in-the-pediatric-population
#15
REVIEW
Suril Patel, Jarred Marshak, Fredric Daum, Shahzad Iqbal
BACKGROUND: Endoscopic ultrasound (EUS) is a useful diagnostic and therapeutic tool in the pediatric population. Given the high accuracy and sensitivity of EUS, it is particularly effective in evaluating pancreaticobiliary disease. Published literature in the use of pediatric EUS is limited. Therefore we aimed to review the current literature for EUS indications, safety, and effectiveness for the pediatric population. DATA SOURCES: English language articles on the use of pediatric endoscopic ultrasound in evaluating pancreaticobiliary diseases were retrieved from PubMed/ MEDLINE...
April 10, 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28375170/serum-metabolomic-profiles-for-human-pancreatic-cancer-discrimination
#16
Takao Itoi, Masahiro Sugimoto, Junko Umeda, Atsushi Sofuni, Takayoshi Tsuchiya, Shujiro Tsuji, Reina Tanaka, Ryosuke Tonozuka, Mitsuyoshi Honjo, Fuminori Moriyasu, Kazuhiko Kasuya, Yuichi Nagakawa, Yuta Abe, Kimihiro Takano, Shigeyuki Kawachi, Motohide Shimazu, Tomoyoshi Soga, Masaru Tomita, Makoto Sunamura
This study evaluated the clinical use of serum metabolomics to discriminate malignant cancers including pancreatic cancer (PC) from malignant diseases, such as biliary tract cancer (BTC), intraductal papillary mucinous carcinoma (IPMC), and various benign pancreaticobiliary diseases. Capillary electrophoresismass spectrometry was used to analyze charged metabolites. We repeatedly analyzed serum samples (n = 41) of different storage durations to identify metabolites showing high quantitative reproducibility, and subsequently analyzed all samples (n = 140)...
April 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28373479/eligibility-criteria-specific-to-pancreaticoduodenectomy-for-octogenarians-single-center-opinion
#17
Shunichi Shiozawa, Takebumi Usui, Kotaro Kuhara, Akira Tsuchiya, Tatsuomi Miyauchi, Teppei Kono, Yukio Shimojima, Shinichi Asaka, Kentaro Yamaguchi, Hajime Yokomizo, Takeshi Shimakawa, Kazuhiko Yoshimatsu, Takao Katsube, Yoshihiko Naritaka
BACKGROUND/AIM: Pancreaticoduodenectomy (PD) treatment outcomes in elderly patients have been reported to be acceptable, but the eligibility criteria are not clear. To elucidate the importance of PD in octogenarians in particular, we set five eligibility criteria for elderly patients based on preoperative cardiac and pulmonary function, nutritional status, daily activity status, and psychological independence status for the first time and evaluated prospectively whether the validity of patient selection was adaptable...
April 2017: Anticancer Research
https://www.readbyqxmd.com/read/28365915/autoimmune-pancreatitis
#18
REVIEW
Shounak Majumder, Naoki Takahashi, Suresh T Chari
Autoimmune pancreatitis (AIP) is a chronic fibroinflammatory disease of the pancreas that belongs to the spectrum of immunoglobulin G-subclass4-related diseases (IgG4-RD) and typically presents with obstructive jaundice. Idiopathic duct-centric pancreatitis (IDCP) is a closely related but distinct disease that mimics AIP radiologically but manifests clinically most commonly as recurrent acute pancreatitis in young individuals with concurrent inflammatory bowel disease. IgG4 levels are often elevated in AIP and normal in IDCP...
April 1, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28364277/pediatric-choledochal-cysts-diagnosis-and-current-management
#19
REVIEW
Kevin C Soares, Seth D Goldstein, Mounes A Ghaseb, Ihab Kamel, David J Hackam, Timothy M Pawlik
Choledochal cysts are rare congenital disorders first described by Vater and Ezler in 1723. Their exact etiology remains incompletely understood; however, an anomalous pancreaticobiliary union (APBDU) and subsequent reflux of biliary contents into the biliary tree are thought to play a role. Accordingly, APBDU-associated choledochal cyst patients are significantly more likely to have evidence of hepatitis, cholangitis or pancreatitis and pathologically confirmed inflammation. In 1977, Todani and colleagues modified the original Alonso-Lej classification to include five types of CC...
June 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28343314/rectus-abdominis-atrophy-after-ventral-abdominal-incisions-midline-versus-chevron
#20
Y Vigneswaran, E Poli, M S Talamonti, S P Haggerty, J G Linn, M B Ujiki
PURPOSE: Although many outcomes have been compared between a midline and chevron incision, this is the first study to examine rectus abdominis atrophy after these two types of incisions. METHODS: Patients undergoing open pancreaticobiliary surgery between 2007 and 2011 at our single institution were included in this study. Rectus abdominis muscle thickness was measured on both preoperative and follow-up computed tomography (CT) scans to calculate percent atrophy of the muscle after surgery...
March 25, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
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