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small bowel bacterial overgrowth

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https://www.readbyqxmd.com/read/28480652/obesity-is-inversely-related-to-hydrogen-producing-small-intestinal-bacterial-overgrowth-in-non-constipation-irritable-bowel-syndrome
#1
Seung Eun Jung, Nam Seok Joo, Kyung Sun Han, Kyu Nam Kim
There have been inconsistent findings on the association of obesity and non-constipation irritable bowel syndrome (IBS). Small intestinal bacterial overgrowth (SIBO) with hydrogen (H₂) gas forming-microflora causes non-constipation IBS. But, the effect of H₂ producing SIBO on obesity in non-constipation IBS patients has not been studied yet. The aim of this study was to investigate the association between obesity and SIBO in non-constipation IBS patients. We reviewed the charts of patients who showed IBS symptoms along with the documented results of their lactulose hydrogen breath test (LHBT) for SIBO...
June 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28470846/systematic-review-interventions-for-abdominal-pain-management-in-inflammatory-bowel-disease
#2
REVIEW
C Norton, W Czuber-Dochan, M Artom, L Sweeney, A Hart
BACKGROUND: Abdominal pain is frequently reported by people with inflammatory bowel disease (IBD), including in remission. Pain is an under-treated symptom. AIM: To systematically review evidence on interventions (excluding disease-modifying interventions) for abdominal pain management in IBD. METHODS: Databases (MEDLINE, EMBASE, PsycInfo, CINAHL, Scopus, Cochrane Library) were searched (February 2016). Two researchers independently screened references and extracted data...
May 4, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28321329/utility-of-the-wireless-motility-capsule-and-lactulose-breath-testing-in-the-evaluation-of-patients-with-parkinson-s-disease-who-present-with-functional-gastrointestinal-symptoms
#3
Andrew Su, Rita Gandhy, Carrolee Barlow, George Triadafilopoulos
BACKGROUND: The aetiology and origin of gastrointestinal symptoms in Parkinson's disease (PD) remains poorly understood. Gastroparesis, small bowel transit delay and bacterial overgrowth may, individually or collectively, play a role. AIMS: In patients with PD and functional gastrointestinal symptoms, we aimed to determine the utility of the wireless motility capsule and lactulose breath tests in further defining their symptoms' aetiology. METHODS: In this retrospective cohort study, consecutive patients with PD and functional gastrointestinal symptoms underwent clinical assessment, as well as wireless motility capsule and lactulose breath testing using standard protocols...
2017: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/28274108/small-intestinal-bacterial-overgrowth-and-irritable-bowel-syndrome-a-bridge-between-functional-organic-dichotomy
#4
REVIEW
Uday C Ghoshal, Ratnakar Shukla, Ujjala Ghoshal
The pathogenesis of irritable bowel syndrome (IBS), once thought to be largely psychogenic in origin, is now understood to be multifactorial. One of the reasons for this paradigm shift is the realization that gut dysbiosis, including small intestinal bacterial overgrowth (SIBO), causes IBS symptoms. Between 4% and 78% of patients with IBS and 1% and 40% of controls have SIBO; such wide variations in prevalence might result from population differences, IBS diagnostic criteria, and, most importantly, methods to diagnose SIBO...
March 15, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28267037/intravenous-lipid-emulsions-in-pediatric-patients-with-intestinal-failure
#5
Olivier Goulet, Cécile Lambe
The incidence of cholestatic liver disease (CLD) in pediatric patients suffering intestinal failure (IF) is not well established. Due to persistent portal inflammation, about 20% of these patients will progress to end-stage intestinal failure associated liver disease (IFALD) leading to liver transplant or death. PURPOSE OF REVIEW: Premature babies as well as infants with short bowel syndrome (SBS) and repeated sepsis (catheter or small intestinal bacterial overgrowth related) are at risk of developing CLD...
April 2017: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/28257307/small-intestinal-bacterial-overgrowth-as-a-cause-for-irritable-bowel-syndrome-guilty-or-not-guilty
#6
Imran Aziz, Hans Törnblom, Magnus Simrén
PURPOSE OF REVIEW: Small intestinal bacterial overgrowth (SIBO) has been proposed as a cause of irritable bowel syndrome (IBS). However, this relationship has been subject to controversy. This review aims to provide a current perspective on the SIBO-IBS hypothesis. RECENT FINDINGS: Case-control studies evaluating the prevalence of SIBO in IBS and healthy individuals have shown conflicting results. Moreover, the tests available in routine clinical practice to diagnose SIBO are not valid and lack both sensitivity and specificity...
May 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28244675/the-clinical-value-of-breath-hydrogen-testing
#7
REVIEW
Chu K Yao, Caroline J Tuck
Breath hydrogen testing for assessing the presence of carbohydrate malabsorption is frequently applied to refine dietary restrictions on a low fermentable carbohydrate (FODMAP) diet. Its application has also been extended for the detection of small intestinal bacterial overgrowth. Recently, several caveats of its methodology and interpretation have emerged. A review of the evidence surrounding its application in the management of patients with a functional bowel disorder was performed. Studies were examined to assess limitations of testing methodology, interpretation of results, reproducibility, and how this relates to clinical symptoms...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28149017/malabsorption-orocecal-transit-time-and-small-intestinal-bacterial-overgrowth-in-type-2-diabetic-patients-a-connection
#8
S V Rana, Aastha Malik, Sanjay K Bhadada, Naresh Sachdeva, Rajesh Kumar Morya, Gaurav Sharma
Type 2 diabetes mellitus consists of dysfunctions characterized by hyperglycemia and resulting from combination of resistance to insulin action and inadequate insulin secretion. Most of diabetic patients report significant gastrointestinal symptoms. Entire GI tract can be affected by diabetes from oral cavity to large bowel and anorectal region. Proteins, carbohydrates, fats, and most fluids are absorbed in small intestine. Malabsorption may occurs when proper absorption of nutrients does not take place due to bacterial overgrowth or altered gut motility...
March 2017: Indian Journal of Clinical Biochemistry: IJCB
https://www.readbyqxmd.com/read/28134688/progress-with-treating-the-microbial-dysbiosis-associated-with-irritable-bowel-syndrome
#9
James S Pearson, Peter J Whorwell
PURPOSE OF REVIEW: Microbial dysbiosis is receiving increasing attention as possibly being important in the pathophysiology of irritable bowel syndrome. This review will summarize the most recent literature addressing attempts to explore and target the microbiome in patients with irritable bowel syndrome. RECENT FINDINGS: Manipulation of the intestinal microbiota in irritable bowel syndrome is receiving increasing attention. Traditionally, dietary manipulation has been utilized...
January 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28078798/systematic-review-with-meta-analysis-rifaximin-is-effective-and-safe-for-the-treatment-of-small-intestine-bacterial-overgrowth
#10
REVIEW
L Gatta, C Scarpignato
BACKGROUND: Small intestinal bacterial overgrowth (SIBO) is a heterogeneous syndrome, characterised by an increased number and/or abnormal type of bacteria in the small bowel. Over the past decades, rifaximin has gained popularity for this indication despite its use is not evidence based. AIM: To perform a systematic review and meta-analysis to summarise evidence about the efficacy and safety of rifaximin to eradicate SIBO in adult patients. METHODS: MEDLINE, EMBASE, CCRCT, Scopus and Web of Science were searched from inception to March 16, 2015 for RCTs and observational studies...
March 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27652124/is-it-bowel-associated-dermatosis-arthritis-syndrome-induced-by-small-intestinal-bacteria-overgrowth
#11
Hongjun Zhao, Lijuan Zhao, Wei Shi, Hui Luo, Liping Duan, Yunhui You, Yisha Li, Xiaoxia Zuo
INTRODUCTION: Bowel-associated dermatosis-arthritis syndrome is rare systemic diseases characterized by a prodrome of fever, chills, and influenza-like symptoms with subsequent skin eruptions, myalgias, and polyarthralgias. It is reported to be occurred in Intestinal bypass surgery and inflammatory bowel disease. CASE DESCRIPTION: Herein, we described a 29-years-old man with Bowel-associated dermatosis-arthritis syndrome. He had no history of gastrointestinal surgery and inflammatory bowel disease...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27650225/lubiprostone-accelerates-intestinal-transit-and-alleviates-small-intestinal-bacterial-overgrowth-in-patients-with-chronic-constipation
#12
Irene Sarosiek, Mohammad Bashashati, Alicia Alvarez, Mark Hall, Nagasri Shankar, Yvette Gomez, Richard W McCallum, Jerzy Sarosiek
BACKGROUND: Lubiprostone is an effective treatment for chronic constipation (CC). The mechanism of action of lubiprostone is through increasing fluid secretion and lubrication of the intestinal lumen. The effects of lubiprostone on gastrointestinal transit and small intestinal bacterial overgrowth (SIBO) have not been adequately explored. The current study was designed to investigate whether lubiprostone (1) alters gastrointestinal transit and (2) affects SIBO in patients with constipation...
September 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/27648298/utility-of-wireless-motility-capsule-and-lactulose-breath-testing-in-the-evaluation-of-patients-with-chronic-functional-bloating
#13
George Triadafilopoulos
BACKGROUND: The precise aetiology of chronic bloating remains poorly understood and underlying gastroparesis, small bowel bacterial overgrowth and colonic inertia may, individually or collectively, play a role. AIMS: In this retrospective cohort analysis of symptomatic patients with chronic persistent bloating, we determined the clinical utility of wireless motility capsule and lactulose breath test in further defining the underlying aetiology for functional bloating...
2016: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/27639806/proton-pump-inhibitors-increase-risk-for-hepatic-encephalopathy-in-patients-with-cirrhosis-in-a-population-study
#14
Chia-Fen Tsai, Mu-Hong Chen, Yen-Po Wang, Chi-Jen Chu, Yi-Hsiang Huang, Han-Chieh Lin, Ming-Chih Hou, Fa-Yauh Lee, Tung-Ping Su, Ching-Liang Lu
BACKGROUND & AIMS: Hepatic encephalopathy (HE) is a serious complication of cirrhosis and is associated with gut dysbiosis. Proton pump inhibitors (PPIs), frequently prescribed to patients with cirrhosis, can contribute to small-bowel bacterial overgrowth. We investigated whether PPI predisposes patients with cirrhosis to HE using a large database of patients. METHODS: We performed a case-control study nested within a sample of Taiwan National Health Insurance beneficiaries (n = 1,000,000), followed up longitudinally from 1998 through 2011...
January 2017: Gastroenterology
https://www.readbyqxmd.com/read/27547007/use-of-rifaximin-in-gastrointestinal-and-liver-diseases
#15
REVIEW
Rani H Shayto, Rachel Abou Mrad, Ala I Sharara
Rifaximin is a broad spectrum oral antibiotic with antimicrobial activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. It is poorly absorbed and thus has a highly favorable safety profile. Rifaximin has been shown to be effective in the treatment of traveler's diarrhea, functional bloating and irritable bowel syndrome, small bowel bacterial overgrowth and in the prevention of recurrent overt hepatic encephalopathy. In addition, there is emerging evidence for a possible beneficial effect of rifaximin in the treatment of uncomplicated diverticular disease and in the prevention of recurrent diverticulitis...
August 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27501017/rosacea-and-gastrointestinal-disorders-a-population-based-cohort-study
#16
A Egeberg, L B Weinstock, E P Thyssen, G H Gislason, J P Thyssen
BACKGROUND: Rosacea is a common inflammatory facial skin condition. Recent genetic and epidemiological studies have suggested pathogenic links between rosacea and gastrointestinal disorders, but data are limited. OBJECTIVES: The objective was to investigate the association between rosacea and coeliac disease (CeD), Crohn disease (CD), ulcerative colitis (UC), Helicobacter pylori infection (HPI), small intestinal bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS), respectively...
January 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/27402085/small-intestinal-bacterial-overgrowth-is-associated-with-irritable-bowel-syndrome-and-is-independent-of-proton-pump-inhibitor-usage
#17
Evangelos J Giamarellos-Bourboulis, Emmanouel Pyleris, Charalambos Barbatzas, Aikaterini Pistiki, Mark Pimentel
BACKGROUND: Current knowledge suggests that small intestinal overgrowth participates in the pathogenesis of irritable bowel syndrome. It is questionable if this association is modulated by intake of proton pump inhibitors (PPIs). METHODS: In a prospective study, quantitative cultures of duodenal aspirates were performed for aerobic species in 897 consecutive patients undergoing upper GI tract endoscopy. SIBO was defined as equal to or more than 10(3) cfu/ml. The effect of PPI intake on the relationship between SIBO and IBS was the primary endpoint...
July 11, 2016: BMC Gastroenterology
https://www.readbyqxmd.com/read/27379166/small-intestinal-bacterial-overgrowth-in-patients-with-irritable-bowel-syndrome-clinical-characteristics-psychological-factors-and-peripheral-cytokines
#18
Hua Chu, Mark Fox, Xia Zheng, Yanyong Deng, Yanqin Long, Zhihui Huang, Lijun Du, Fei Xu, Ning Dai
Small intestinal bacterial overgrowth (SIBO) has been implicated in the pathogenesis of irritable bowel syndrome (IBS). Psychosocial factors and low-grade colonic mucosal immune activation have been suggested to play important roles in the pathophysiology of IBS. In total, 94 patients with IBS and 13 healthy volunteers underwent a 10 g lactulose hydrogen breath test (HBT) with concurrent (99m)Tc scintigraphy. All participants also completed a face-to-face questionnaire survey, including the Hospital Anxiety and Depression Scale, Life Event Stress (LES), and general information...
2016: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/27373356/-clinical-features-of-irritable-bowel-syndrome-with-small-intestinal-bacterial-overgrowth-and-a-preliminary-study-of-effectiveness-of-rifaximin
#19
Z J Liu, H Wei, L P Duan, S W Zhu, L Zhang, K Wang
OBJECTIVE: To investigate the prevalence and clinical features of small intestinal bacterial overgrowth (SIBO) in diarrhea-predominant irritable bowel syndrome (IBS-D) patients detected by hydrogen and methane in lactulose breath test (LBT), and to study the effects of rifaximin in IBS-D patients. METHODS: Consecutive patients with IBS-D who met Rome Ⅲ criteria, and gender- and age-matched healthy volunteers were enrolled from March 2015 to January 2016 in Peking University Third Hospital...
June 28, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27333193/gut-and-liver-in-vasculitic-disorders
#20
Ulf Müller-Ladner
BACKGROUND: Although the gastrointestinal (GI) tract including its related organs is not generally regarded as one of the primary organ systems of primary and secondary vasculitic disorders, there are numerous mechanisms of these diseases operative in or around the different structures and compartments of the GI tract. KEY MESSAGES: A majority of the respective clinical symptoms and problems are linked to an alteration of (peri)vascular homeostasis. Alteration of perivascular matrix metabolism can also affect the functional integrity and motility of the GI tract...
2016: Digestive Diseases
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