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Bone deformity

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https://www.readbyqxmd.com/read/29667926/proximal-tibia-stress-fracture-with-osteoarthritis-of-knee-radiological-and-functional-analysis-of-one-stage-tka-with-long-stem
#1
Dhanasekaran Soundarrajan, Natesan Rajkumar, Palanisamy Dhanasekararaja, Shanmuganathan Rajasekaran
INTRODUCTION: Proximal tibia stress fractures with knee osteoarthritis pose a challenging situation. We evaluated the radiological and functional outcome of one-stage total knee arthroplasty (TKA) and long stem for patients with varied grades of knee arthritis and proximal tibia stress fractures.  Methods: We analysed 20 patients from April 2012 to March 2017 with proximal tibia stress fractures associated with knee osteoarthritis of varied grades. Out of 20 patients, five were acute fresh fractures...
2018: SICOT-J
https://www.readbyqxmd.com/read/29665086/severely-impaired-bone-material-quality-in-chihuahua-zebrafish-resembles-classical-dominant-human-osteogenesis-imperfecta
#2
Imke A K Fiedler, Felix N Schmidt, Eva M Wölfel, Christine Plumeyer, Petar Milovanovic, Roberta Gioia, Francesca Tonelli, Hrishikesh A Bale, Katharina Jähn, Roberta Besio, Antonella Forlino, Björn Busse
Excessive skeletal deformations and brittle fractures in the vast majority of patients suffering from osteogenesis imperfecta (OI) are a result of substantially reduced bone quality. Since the mechanical competence of bone is dependent on the tissue characteristics at small length scales, it is of crucial importance to assess how osteogenesis imperfecta manifests at the micro- and nanoscale of bone. In this context, the Chihuahua (Chi/ +) zebrafish, carrying a heterozygous glycine substitution in the α1 chain of collagen type I, has recently been proposed as suitable animal model of classical dominant OI, showing skeletal deformities, altered mineralization patterns and a smaller body size...
April 17, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29660737/treatment-of-a-paediatric-distal-femoral-malunion-deformity
#3
Greta S Pavarotti, Randy J Boudrieau
OBJECTIVE:  The aim of this article was to describe the surgical re-alignment technique and stabilization of a distal femoral deformity in a 6-week-old, male, Foxhound. METHODS:  A healing metaphyseal fracture, resulting in a valgus deformity with internal rotation, was observed just proximal to the distal femoral physis. The deformity was treated by an opening wedge osteotomy with lateral translation and external rotation of the distal epiphysis using a guide-wire technique; a corticocancellous allograft bridged the defect, which was stabilized with a 2...
April 16, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29658056/bone-toughening-through-stress-induced-non-collagenous-protein-denaturation
#4
Z Wang, D Vashishth, R C Picu
Bone toughness emerges from the interaction of several multiscale toughening mechanisms. Recently, the formation of nanoscale dilatational bands and hence the accumulation of submicron diffuse damage were suggested as an important energy dissipation processes in bone. However, a detailed mechanistic understanding of the effect of this submicron toughening mechanism across multiple scales is lacking. Here, we propose a new three-dimensional ultrastructure volume element model showing the formation of nanoscale dilatational bands based on stress-induced non-collagenous protein denaturation and quantify the total energy released through this mechanism in the vicinity of a propagating crack...
April 16, 2018: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/29657461/growth-modulation-for-coronal-deformity-correction-by-using-eight-plates-systematic-review
#5
REVIEW
Sanjay Kumar, S V Sonanis
Introduction: Coronal deformities are commonly encountered in paediatric orthopaedics and surgical treatment is indicated for severe deformities causing pain, function and cosmetic problems. In a growing bone, major surgical intervention like osteotomy with internal or external fixation can be avoided by growth modulation (hemiepiphysiodesis) using 8-plates. Our aim is to review the published literature on the use of 8-plates for deformity correction. Methods: We conducted a systematic review on 8-plate growth modulation for coronal deformity correction...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29648876/use-of-patient-specific-3d-printed-titanium-implants-for-complex-foot-and-ankle-limb-salvage-deformity-correction-and-arthrodesis-procedures
#6
Travis J Dekker, John R Steele, Andrew E Federer, Kamran S Hamid, Samuel B Adams
BACKGROUND: The advancement of 3D printing technology has allowed for the use of custom-designed implants for difficult-to-treat foot and ankle pathologies. This study reports on the radiographic and functional outcomes of a case series of patients treated with patient-specific 3D-printed titanium implants. METHODS: Fifteen consecutive patients treated with custom-designed 3D-printed implant cages for severe bone loss, deformity correction, and/or arthrodesis procedures were included in this study...
April 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29629580/current-concepts-in-the-surgical-management-of-adolescent-idiopathic-scoliosis
#7
A D Tambe, S J Panikkar, P A Millner, A I Tsirikos
Adolescent idiopathic scoliosis (AIS) is a complex 3D deformity of the spine. Its prevalence is between 2% and 3% in the general population, with almost 10% of patients requiring some form of treatment and up to 0.1% undergoing surgery. The cosmetic aspect of the deformity is the biggest concern to the patient and is often accompanied by psychosocial distress. In addition, severe curves can cause cardiopulmonary distress. With proven benefits from surgery, the aims of treatment are to improve the cosmetic and functional outcomes...
April 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29627140/difference-in-the-fusion-rate-and-bone-formation-between-artificial-bone-and-iliac-autograft-inside-an-inter-body-fusion-cage-a-comparison-between-porous-hydroxyapatite-type-1-collagen-composite-and-autologous-iliac-bone
#8
Junichi Kushioka, Takashi Kaito, Takahiro Makino, Hiroyasu Fujiwara, Hiroyuki Tsukazaki, Shota Takenaka, Yusuke Sakai, Hideki Yoshikawa
BACKGROUND: Lateral inter-body fusion (LIF) using cages with a large bone grafting space can lead to a shortage of autologous grafting materials. The use of artificial bone is an option to increase the volume of grafting materials. However, the rate of bony fusion for these materials compared to that of autologous bone is unclear. METHODS: The bone fusion rate for artificial bone (HAp/Col) and autologous iliac bone (IBG) graft among 23 patients who had undergone LIF (total 66 disc levels) combined with multilevel posterior corrective fusion for the treatment of adult spinal deformity was retrospectively evaluated...
April 4, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29621078/a-patient-with-severe-lower-face-degloving-injury
#9
Ivo Cavalcante Pita Neto, Jéferson Martins Pereira Lucena Franco, Eduardo Chaves Moreno, Pablo Pita, Francisco Aurelio Lucchesi Sandrini, David Gomes de Alencar Gondim
Avulsions of mandible are among the most devastating lesions observed in cranio-maxillofacial traumas. They present an important health problem because of the high risk of morbidity related to deformities that cause functional limitations and esthetic changes. The avulsions commonly result from high-energy effects, which cause complete or partial separation of the mandibular bone of the face. As a result of the intense aggression, the skin and subcutaneous tissues of the bone are usually removed, affecting muscles, fascia, blood vessels, and the surrounding nerves...
April 4, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29620655/clinical-characteristics-and-treatment-outcomes-in-camurati-engelmann-disease-a-case-series
#10
Yoon-Myung Kim, Eungu Kang, Jin-Ho Choi, Gu-Hwan Kim, Han-Wook Yoo, Beom Hee Lee
BACKGROUND: Camurati-Engelmann disease is an extremely rare disease characterized by hyperostosis of multiple long bones. This condition is caused by heterozygous mutations in the TGFB1 gene. METHODS: We describe the clinical and genetic characteristics of 4 Korean patients with this rare disease diagnosed at Asan Medical Center in Korea between June 2012 and May 2016, to increase awareness about this condition among general physicians and orthopedists. The presenting features, biochemical findings, radiographic and nuclear imaging findings, molecular analysis, and treatment outcomes of 4 patients were reviewed retrospectively...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29620206/genetic-analysis-of-a-congenital-split%C3%A2-hand-split%C3%A2-foot-malformation-4-pedigree
#11
Xiao Yang, Xinfu Lin, Yaobin Zhu, Jiewei Luo, Genhui Lin
In the present study whole-exome sequencing using the Complete Genomics platform was employed to scan a proband from a split‑hand/split‑foot malformation (SHFM) 4 family. The missense mutation c.728G>A (p.Arg243Gln) in the TP63 gene was revealed to be associated with SHFM. Sanger sequencing confirmed the sequences of the proband and his father. The father was diagnosed with SHFM and harbored a CGG‑to‑CAG mutation in exon 5, which produced a R243Q substitution in the zinc binding site and dimerization site of TP63...
March 29, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29619932/mortality-and-morbidity-in-patients-with-osteogenesis-imperfecta-in-denmark
#12
Lars Folkestad
Ostegenesis imperfecta (OI) is a hereditary disease of the connective tissue caused by mutations to, mainly, the genes that are involved in the biosynthesis of collagen type 1. Patients are grouped according to clinical severity and mode of inheritance according to Sillence's classification (originally 1979, updated 2014). According to our data, the population prevalence of OI in Denmark was 10.3 per 100,000, with 575 patients registered with an OI diagnosis in the National Patient Register and alive at the end of 2012 out of a total population of 5,602,628 persons...
April 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29619361/how-to-prevent-costal-cartilage-graft-warping-in-secondary-correction-of-cleft-lip-nasal-deformity
#13
Hung-Chang Chen, Cheng-I Yen, Shih-Yi Yang, Yen-Chang Hsiao
Introduction: Autologous costal cartilage dorsal onlay graft is widely used for dorsum and radix augmentation in secondary cleft lip nasal rhinoplasty. The most common drawback of costal cartilage dorsal onlay graft is warping. The purpose of this article is to describe our chimeric autologous costal cartilage graft technique, which prevents warping significantly. "Chimeric" means the combination of 2 different tissues (bone and cartilage) to make a single dorsal onlay graft...
February 2018: Plastic Surgery
https://www.readbyqxmd.com/read/29618896/cortical-bone-graft-and-gtr-membrane-as-ceiling-effect-in-alveolar-bone-grafting
#14
Philip Mathew, P Varun Menon
Background: In orofacial cleft deformity cases, bone grafting is a very essential step in reconstruction of the residual alveolar cleft defect. Material and Methods: Though various authors have put forth different techniques and graft sources for alveolar bone grafting, at our center, we have used iliac crest as the graft source and cortical bone graft with GTR membrane as "ceiling effect". Results: We have evaluated a series of cases of secondary alveolar bone grafting done with this technique by same surgeon at our center and have found great success...
June 2018: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29618890/modified-le-fort-iii-osteotomy-different-applications
#15
J M García Y Sánchez, C L Gómez Rodríguez, G Pacheco Rubio
Summary: Based on the new concepts of the modified Le Fort III osteotomy (MLFIIIO), Three variations of this technique are implemented: (A) the modified osteotomy Le Fort III Champy (1980) technique to be described with the use of surgical guides, and subciliary approach or an transconjunctival approach. Excellent technique for horizontal advancement no further to 6 mm, without requiring any type of graft.. (B) The modified Le Fort III osteotomy in "Z": to solve horizontal (posterior anterior) problems of more than 6 mm without bone grafting...
June 2018: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29618867/nasal-reconstruction-with-pre-laminated-forehead-flap
#16
N S Prasanna
Loss of nasal skin as well as loss of both lateral alar cartilages and vestibular lining with exposure of septum presents a grotesque deformity by itself, with further danger of loss of nasal bones and other cartilaginous structures leading to total loss of nose. The Goal of the treatment is to restore the skin cover as well as lining and cartilage support, restoring nose while avoiding the deformity. In an elderly patient with Spiritual restrictions, with diabetes and Hypertension, the treatment was needed to be carried out under local anesthesia as a daycare procedure...
September 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/29616216/microstructure-evolution-in-mg-zn-zr-gd-biodegradable-alloy-the-decisive-bridge-between-extrusion-temperature-and-performance
#17
Huai Yao, Jiu-Ba Wen, Yi Xiong, Yan Lu, Marko Huttula
Being a biocompatible metal with similar mechanical properties as bones, magnesium bears both biodegradability suitable for bone substitution and chemical reactivity detrimental in bio-ambiences. To benefit its biomaterial applications, we developed Mg-2.0Zn-0.5Zr-3.0Gd (wt%) alloy through hot extrusion and tailored its biodegradability by just varying the extrusion temperatures during alloy preparations. The as-cast alloy is composed of the α-Mg matrix, a network of the fish-bone shaped and ellipsoidal (Mg, Zn)3 Gd phase, and a lamellar long period stacking ordered phase...
2018: Frontiers in Chemistry
https://www.readbyqxmd.com/read/29610615/surgical-management-of-facial-features-of-robinow-syndrome-a-case-report
#18
Aida M Mossaad, Moustapha A Abdelrahman, Mostafa A Ibrahim, Hatem H Al Ahmady
BACKGROUND: Robinow Syndrome is an extremely rare genetic disorder characterised by abnormalities in head, face and external genitalia. This disorder exists in dominant pattern with moderate symptoms and recessive pattern with more physical and skeletal abnormalities. It was first introduced by Menihard Robinow in 1969. It was related to chromosome 9q22 ROR2 gene related to bone and cartilage growth aspects. CASE PRESENTATION: A 17-year-old Egyptian male presented to National Research Centre Orodental genetics Clinic with typical features of short stature and facial dysmorphism weighted 50 Kg and measured 150 cm height complaining of facial dis figurement...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29610609/the-outcome-of-using-a-jamshidi-biopsy-trocar-needle-in-a-novel-technique-for-bone-grafting-in-percutaneous-internal-fixation-of-scaphoid-non-union
#19
Syed Bokhari, Saifullah Hadi, Fahad Hossain, Bernd Ketzer
INTRODUCTION: We report the outcome of using a novel technique of minimally invasive internal fixation and distal radius bone grafting using the Jamishidi Trephine needle and biopsy/graft capture device. METHODS: The technique utilises a 8 mm incision at the distal pole of the scaphoid. The non-union is excavated using the standard Acutrak drill. An 8 gauge Jamshidi trephine needle is used to harvest bone graft from the distal radius which is impacted into the scaphoid and fixed with an Acutrak screw...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29609637/primary-total-knee-arthroplasty-using-constrained-condylar-knee-design-for-severe-deformity-and-stiffness-of-knee-secondary-to-post-traumatic-arthritis
#20
Saroj Rai, Xianzhe Liu, Xiaobo Feng, Bimal Rai, Nira Tamang, Jing Wang, Shunan Ye, Shuhua Yang
BACKGROUND: Key to a successful outcome of total knee arthroplasty (TKA) is to attain optimum alignment, adequate balance, and deformity correction. In primary TKA, this can be achieved efficiently by posterior stabilized (PS) design with or without the sub-periosteal release. However, certain circumstances such as post-traumatic arthritis are often associated with severe deformities with a significant bone defect, stiffness, and instability. Such deformities are extremely difficult to balance with soft tissue release only and require additionally constrained prostheses even in primary TKA...
April 2, 2018: Journal of Orthopaedic Surgery and Research
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