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Bone deformity

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https://www.readbyqxmd.com/read/28644737/circulatory-cnp-rescues-craniofacial-hypoplasia-in-achondroplasia
#1
S Yamanaka, Kazumasa Nakao, N Koyama, Y Isobe, Y Ueda, Y Kanai, E Kondo, T Fujii, M Miura, A Yasoda, Kazuwa Nakao, K Bessho
Achondroplasia is the most common genetic form of human dwarfism, characterized by midfacial hypoplasia resulting in occlusal abnormality and foramen magnum stenosis, leading to serious neurologic complications and hydrocephalus. Currently, surgery is the only way to manage jaw deformity, neurologic complications, and hydrocephalus in patients with achondroplasia. We previously showed that C-type natriuretic peptide (CNP) is a potent stimulator of endochondral bone growth of long bones and vertebrae and is also a potent stimulator in the craniofacial region, which is crucial for midfacial skeletogenesis...
June 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28643081/distraction-osteogenesis-reconstruction-of-large-segmental-bone-defects-after-primary-tumor-resection-pitfalls-and-benefits
#2
REVIEW
Jan Lesensky, Daniel E Prince
Successful cure is achieved in almost 70% of patients with primary bone sarcomas with currently available therapies. Some soft tissue sarcomas require wide bone resection in order to achieve appropriate margins for cure of disease, and patients undergoing these procedures need durable reconstruction. Biological reconstruction has been shown to provide patients with superior long-term results over other alternatives. Distraction osteogenesis is well studied in the correction of deformities as well as in addressing some congenital musculoskeletal pathologies...
June 22, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28642853/paget-s-disease-skeletal-manifestations-and-effect-of-bisphosphonates
#3
Ho Kang, Young-Chang Park, Kyu Hyun Yang
BACKGROUND: Paget's disease of bone leads to change in the shape and size of the bone and results in reduced bone strength, leading to the complications of deformity, arthritis, and fracture. Due to unknown reasons, Paget's disease is rare in Asian descendants. We report the cases of Paget's disease who visited our institute for 15 years and reviewed the literatures. METHODS: We retrospectively reviewed the medical records and radiograms of 8 patients (6 female and 2 male) who were diagnosed as Paget's disease of bone...
May 2017: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/28642192/applications-of-3d-orbital-computer-assisted-surgery-cas
#4
Paolo Scolozzi
INTRODUCTION: The purpose of the present report is to describe the indications for use of 3D orbital computer-assisted surgery (CAS). PATIENTS AND METHODS: We analyzed the clinical and radiological data of all patients with orbital deformities treated using intra-operative navigation and CAD/CAM techniques at the Hôpitaux Universitaires de Genève, Switzerland, between 2009 and 2016. We recorded age and gender, orbital deformity, technical and surgical procedure and postoperative complications...
June 19, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28639070/osseous-cartilaginous-spreader-graft-and-nasal-framework-reconstruction
#5
Safvet Ors
Revision rhinoplasties and saddle nose deformities usually require grafting for reconstruction. Between January 1, 2000, and January 1, 2017, autologous rib grafts were used in 127 secondary and tertiary rhinoplasty patients [(57/127 females) and (70/127 males)]. Osseous-cartilaginous rib grafts (OCRGs) were divided into three parts (i.e., 1/3 upper peripheral, 1/3 central, and 1/3 lower peripheral). The harvested OCRGs were also shaped as vertical strips using a number 11 scalpel blade. These OCRGs were shaped to form the L-strut cartilaginous graft (LSCGs), osseous-cartilaginous spreader grafts (OCSGs), osseous-cartilaginous onlay grafts, nasal valve grafts (NVGs), and lower lateral cartilaginous grafts (LLCGs)...
June 21, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28639069/the-application-of-3d-printing-technology-for-simultaneous-orthognathic-surgery-and-mandibular-contour-osteoplasty-in-the-treatment-of-craniofacial-deformities
#6
Yanju Xiao, Xiumei Sun, Lin Wang, Yaoyao Zhang, Kai Chen, Guomin Wu
BACKGROUND: Because of the limitation of specific preoperative design and surgical templates, orthognathic surgery and mandibular contour osteoplasty are generally performed in two stages. Three-dimensional printing technology has improved the accuracy of the surgery and results in good surgical predictability easily. This study aims to confirm the effectiveness, feasibility and precision of simultaneous mandibular contour osteoplasty and orthognathic surgery with the assistance of 3D printing technology...
June 21, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28638492/importance-of-radiological-evaluation-of-global-spinal-balance-together-with-lower-limb-alignment-in-planning-lumbar-spine-deformity-surgery-illustrative-case-presentation
#7
Mariusz Głowacki, Jerzy Walecki, Przemysław Kołakowski, Danuta Kolońska
BACKGROUND: The presented case illustrates the critical role of a detailed preoperative radiological evaluation in complex spine surgery. CASE REPORT: A 49-year-old patient was admitted for a revision surgery after L3-L5 fusion. Preoperative assessment showed preserved sagittal balance, coronal imbalance and valgus knee deformity. The patient reported pain of 8-10 in VAS (Visual Analogue Scale) and had an ODI (Oswestry Disability Index) of 60%. The first step of the surgery was L2-S1 fusion with decompression and spine deformity correction...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28636229/recovery-from-reproductive-and-morphological-abnormalities-in-medaka-oryzias-latipes-following-a-14-day-exposure-to-diclofenac
#8
Hirofumi Yokota, Kaho Higashi, Erina Hanada, Ei Matsuzaki, Yukinari Tsuruda, Tomoko Suzuki, Eiko Nakano, Sayaka Eguchi
Mating pairs of medaka (Oryzias latipes) were exposed to diclofenac (DCF) at measured concentrations of 0 (control), 7.1, 37, and 78 µg/L for 14 d under static-renewal conditions. Effects on reproductive success, as well as morphological abnormalities, of the fish were assessed. During the exposure period, both fecundity and fertility were significantly decreased in the 37 and 78 µg/L treatments groups, and swollen abdomens in females were observed in all exposure groups. Notably, a defect of the lower jaw also was observed in four male fish: two at 37 µg/L, and the others at 78 µg/L of DCF...
June 21, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28630862/influence-of-deformation-and-stress-between-bone-and-implant-from-various-bite-forces-by-numerical-simulation-analysis
#9
Hsin-Chung Cheng, Boe-Yu Peng, May-Show Chen, Chiung-Fang Huang, Yi Lin, Yung-Kang Shen
Endosseous oral implant is applied for orthodontic anchorage in subjects with multiple tooth agenesis. Its effectiveness under orthodontic loading has been demonstrated clinically and experimentally. This study investigates the deformation and stress on the bone and implant for different bite forces by three-dimensional (3D) finite element (FE) methods. A numerical simulation of deformation and stress distributions around implants was used to estimate the survival life for implants. The model was applied to determine the pattern and distribution of deformations and stresses within the endosseous implant and on supporting tissues when the endosseous implant is used for orthodontic anchorage...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28629558/is-there-a-trend-in-ct-scanning-scaphoid-nonunions-for-deformity-assessment-a-systematic-review
#10
REVIEW
Paul W L Ten Berg, Marieke G A de Roo, Mario Maas, Simon D Strackee
PURPOSE: The effect of scaphoid nonunion deformity on wrist function is uncertain due to the lack of reliable imaging tools. Advanced three-dimensional (3-D) computed tomography (CT)-based imaging techniques may improve deformity assessment by using a mirrored image of the contralateral intact wrist as anatomic reference. The implementation of such techniques depends on the extent to which conventional CT is currently used in standard practice. The purpose of this systematic review of medical literature was to analyze the trend in CT scanning scaphoid nonunions, either unilaterally or bilaterally...
June 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28623060/amniotic-band-syndrome-with-pseudoarthrosis-of-tibia-and-fibula-a-case-report
#11
Anitha Ananthan, Gayatri Athalye Jape, Jean Du Plessis, Peter Annear, Rohan Page, Shripada Rao
Constriction of the lower limb by a congenital amniotic band has been proposed to explain the development of pseudoarthrosis of the tibia and fibula. We report a case of amniotic band syndrome in a preterm female infant with pseudoarthrosis of the tibia and fibula. She was born at 29 weeks of gestation with congenital amniotic bands and was noted to have a severely edematous left foot distal to the constricting band with rudimentary digits. The skin was pink and well perfused with palpable pulses. Radiography demonstrated pseudoarthrosis of the tibia and fibula...
June 13, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28616759/is-dual-semitendinosus-allograft-stronger-than-turndown-for-achilles-tendon-reconstruction-an-in-vitro-analysis
#12
Michael C Aynardi, Lara C Atwater, Roshan Melvani, Brent G Parks, Adrian G Paez, Stuart D Miller
BACKGROUND: Large Achilles tendon defects pose a treatment challenge. The standard treatment with a turndown flap requires a large extensile incision, puts the sural nerve at risk, and demands slow, careful rehabilitation. Dual allograft semitendinosus reconstruction is a new clinical alternative that has the theoretical advantages of a smaller incision, less dissection, and a stronger construct that may allow for faster rehabilitation. QUESTIONS/PURPOSES: In a cadaver biomechanical model, we compared the dual allograft semitendinosus reconstruction with the myofascial turndown in terms of (1) mechanical strength and resistance to deformation and (2) failure mechanisms in reconstruction of large segmental Achilles defects...
June 14, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28614531/alternative-option-for-osteogenesis-imperfecta-and-trigeminal-neuralgia
#13
Leonardo Gilmone Ruschel, Guilherme José Agnoletto, Sonival Cândido Hunhevicz, Daniel Benzecry de Almeida, Walter Oleschko Arruda
Osteogenesis imperfecta (OI) is a bone disorder that can lead to skull base deformities such as basilar invagination, which can cause compression of cranial nerves, including the trigeminal nerve. Trigeminal neuralgia in such cases remains a challenge, given distorted anatomy and deformities. We present an alternative option, consisting in cannulation of the foramen ovale and classical percutaneous treatment. Percutaneous balloon microcompression was performed in a 28 year-old woman with OI and severe trigeminal neuralgia using computed tomography (CT) and radiographic-guided cannulation of the Gasserian ganglion without neuronavigation or stereotactic devices...
April 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28614236/utilization-of-ring-shaped-bone-allograft-for-surgical-treatment-of-adolescent-post-tubercular-kyphosis-a-retrospective-study
#14
Xiang Yin, Peng Liu, Yao-Yao Liu, Wei-Li Fan, Bai-Yi Liu, Jian-Hua Zhao
This study aimed to investigate the mid-term outcome of ring-shaped bone allografts in the surgical treatment of adolescent post-tubercular kyphosis secondary to spinal tuberculosis.The records of adolescent patients diagnosed with spinal tuberculosis who received treatment in our department between 2009 and 2013 were retrospectively reviewed. The anterior approach was used in cases of cervical kyphosis and the posterior approach was used in cases of thoracic and lumbar kyphosis. During the surgery, the ring-shaped bone was used as a structural bone graft associated with the cancellous bone filing in the center portion of the ring shape...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28612705/treatment-of-acetabular-chondral-lesions-with-microfracture-technique
#15
Claudio Mella, Alvaro Nuñez, Ignacio Villalón
INTRODUCTION: Acetabular cartilage lesions are frequently found during hip arthroscopy. In the hip joint they mostly occur secondary to a mechanical overload resulting from a pre-existing deformity as hip dysplasia or femoroacetabular impingement (FAI). Lesions identified during arthroscopy can vary greatly from the earliest stages to the most advanced (full-thickness lesions). These lesions occur in the acetabulum in the early stages of joint damage. Microfractures are indicated in full-thickness chondral defects...
2017: SICOT-J
https://www.readbyqxmd.com/read/28612467/the-effect-of-age-and-demographics-on-rib-shape
#16
Sven A Holcombe, Stewart C Wang, James B Grotberg
Elderly populations have a higher risk of rib fractures and other associated thoracic injuries than younger adults, and the changes in body morphology that occur with age are a potential cause of this increased risk. Rib centroidal path geometry for 20 627 ribs was extracted from computed tomography (CT) scans of 1042 live adult subjects, then fitted to a six-parameter mathematical model that accurately characterizes rib size and shape, and a three-parameter model of rib orientation within the body. Multivariable regression characterized the independent effect of age, height, weight, and sex on the rib shape and orientation across the adult population, and statistically significant effects were seen from all demographic factors (P < 0...
June 13, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28610471/mechanically-loading-cell-hydrogel-constructs-with-low-intensity-pulsed-ultrasound-for-bone-repair
#17
James A Veronick, Fayekah Assanah, Nicole J Piscopo, Yasemin Kutes, Varun Vyas, Bryan D Huey, Yusuf Khan
Low-intensity pulsed ultrasound (LIPUS) has been shown to be effective for orthopaedic fracture repair and non-union defects but the specific mechanism behind its efficacy is still unknown. Previously we have shown a measurable acoustic radiation force at LIPUS intensities traditionally used for clinical treatment and have applied this force to osteoblastic cells encapsulated in type I collagen hydrogels. Our goal here is to provide insight and inform the appropriate design of a cell therapy approach to bone repair in which osteoblasts are embedded in collagen hydrogels, implanted into a bony defect, and then transdermally stimulated using LIPUS-derived acoustic radiation force to enhance bone formation at the earliest time points after bone defect repair...
June 13, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28606606/potential-risks-of-using-cement-augmented-screws-for-spinal-fusion-in-patients-with-low-bone-quality
#18
M Martín-Fernández, A López-Herrradón, A R Piñera, F Tomé-Bermejo, J M Duart, M D Vlad, M G Rodríguez-Arguisjuela, L Álvarez-Galovich
BACKGROUND CONTEXT: Dramatic increases in the average life expectancy have led to increases in the variety of degenerative changes and deformities observed in the aging spine. The elderly population can present challenges for spine surgeons, not only because of increased comorbidities, but also because of the quality of their bones. Pedicle screws are the implants used most commonly in spinal surgery for fixation, but their efficacy depends directly on bone quality. While PMMA-augmented screws represent an alternative for patients with osteoporotic vertebrae, their use has raised some concerns due to the possible association between cement leakages (CLs) and other morbidities...
June 9, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28604992/a-new-bioinspired-collagen-hydroxyapatite-bone-graft-substitute-in-adult-scoliosis-surgery-results-at-3-year-follow-up
#19
Pietro Giorgi, Dario Capitani, Simone Sprio, Monica Sandri, Anna Tampieri, Valentina Canella, Angelo Nataloni, Giuseppe R Schirò
BACKGROUND: Spinal fusion is a common procedure used for surgical treatment of spinal deformity. In recent years, many bone graft substitutes (BGS) have been developed to provide good arthrodesis when the available autologous bone harvested from the patient is not enough. The aim of this study was to analyze the use of a new-generation composite material (RegenOss) made of Mg-hydroxyapatite nanoparticles nucleated on type I collagen to obtain long posterolateral fusion in adult scoliosis surgery...
June 7, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28603707/maxillary-resection-for-cancer-zygomatic-implants-insertion-and-palatal-repair-as-single-stage-procedure-report-of-three-cases
#20
Pietro Salvatori, Antonio Mincione, Lucio Rizzi, Fabrizio Costantini, Alessandro Bianchi, Emma Grecchi, Umberto Garagiola, Francesco Grecchi
BACKGROUND: Oronasal/antral communication, loss of teeth and/or tooth-supporting bone, and facial contour deformity may occur as a consequence of maxillectomy for cancer. As a result, speaking, chewing, swallowing, and appearance are variably affected. The restoration is focused on rebuilding the oronasal wall, using either flaps (local or free) for primary closure, either prosthetic obturator. Postoperative radiotherapy surely postpones every dental procedure aimed to set fixed devices, often makes it difficult and risky, even unfeasible...
December 2017: Maxillofacial Plastic and Reconstructive Surgery
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