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Khalili

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https://www.readbyqxmd.com/read/27904562/hyperhomocysteinemia-low-vitamin-b12-and-low-folic-acid-are-risk-factors-of-cerebral-vascular-thrombosis-in-northwest-iran
#1
Ali Akbar Taheraghdam, Nooriyeh Dalirakbari, Mohammad Khalili, Madjid Soltani, Saeid Sadeghieh Ahari
BACKGROUND: Cerebral vascular thrombosis (CVT) is the thrombosis of intracranial and sinuses. The aim of this is to estimate of risk of low folic acid, low vitamin B12, and hyperhomocysteinemia (hyper-Hcys) for CVT. MATERIALS AND METHODS: A total of 24 patients with CVT and 36 healthy controls participated in a cross-sectional case-control study. The deficient levels of folic acid and vitamin B12 defined as <10(th) percentile of folic acid and vitamin B12 level and hyper-Hcys was defined as >90(th) percentile of homocysteine of control group...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27903228/synthesis-and-evaluation-of-the-hypoglycemic-and-hypolipidemic-activity-of-novel-sulfonamide-benzothiazole-derivatives-of-benzylidene-2-4-thiazolidnedione
#2
Abbas Ahmadi, Mohsen Khalili, Lida Sohrabi, Nazanin Delzendeh, Babak Nahri-Niknafs, Fariba Ansari
Thiazolidinediones (TZDs) and sulfonamides are important and highly consumption class of antidiabetic drugs having insulin sensitizing and stimulating properties in patients with type 2 diabetes, respectively. In this paper, some novel benzothiazole derivatives of TZD-sulfonamides were synthesized (I-IV) and evaluated for anti-hyperglycemic and anti-hyperlipidemic activities in the STZ-induced diabetic rat model. Results indicated that all new conjugated drugs showed significant hypoglycemic activities compared to the control animals that were better for I and IV than others...
November 29, 2016: Mini Reviews in Medicinal Chemistry
https://www.readbyqxmd.com/read/27898365/capillary-electrophoresis-with-online-stacking-in-combination-with-agnps-mcm-41-reinforced-hollow-fiber-solid-liquid-phase-microextraction-for-quantitative-analysis-of-capecitabine-and-its-main-metabolite-5-fluorouracil-in-plasma-samples-isolated-from-cancer
#3
Mehrdad Forough, Khalil Farhadi, Rahim Molaei, Hedayat Khalili, Ramin Shakeri, Asghar Zamani, Amir Abbas Matin
The purpose of this study is the development and validation of a simple, novel, selective and fast off-line microextraction technique combining capillary electrophoresis with in-column field-amplified sample injection (FASI) for the simultaneous determination of capecitabine (CAP) and its active metabolite, 5-Fluorouracil (5-FU), in human plasma. At the moment, there is a lack of using cost-effective CE tool combined with novel miniaturized sample clean-up techniques for analysis of these important anti-cancer agents in plasma samples...
November 18, 2016: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/27894698/dual-effects-of-eugenol-on-the-neuronal-excitability-an-in-vitro-study
#4
Jafar Vatanparast, Samira Khalili, Maryam Naseh
Besides its well-known actions on sensory afferents, eugenol also affects general excitability of the nervous system, but the mechanisms involved in the recent effect, especially through modulation of ion channels, have received much less attention. In this study, we studied the effects of eugenol on the excitability of central neurons of land snail Caucasotachea atrolabiata and tried to elucidate the underlying ionic mechanisms. The lower concentration of eugenol (0.5mM) reversibly reduced the frequency of spontaneous action potentials that was associated with elevation of threshold, reduction of maximum slope of rising phase and prolongation of actin potentials...
November 25, 2016: Neurotoxicology
https://www.readbyqxmd.com/read/27893544/visceral-adiposity-genetic-susceptibility-and-risk-of-complications-among-individuals-with-crohn-s-disease
#5
Kimberley W J Van Der Sloot, Amit D Joshi, Danielle R Bellavance, Katherine K Gilpin, Kathleen O Stewart, Paul Lochhead, John J Garber, Cosmas Giallourakis, Vijay Yajnik, Ashwin N Ananthakrishnan, Behrooz Z Alizadeh, Ramnik J Xavier, Hamed Khalili
INTRODUCTION: Adipose tissue in mesenteric fat plays a key role in systemic and luminal inflammation. However, little is known about the role of visceral adipose tissue (VAT) and its interaction with genetic predisposition in Crohn's disease (CD) progression. METHODS: Our study population included patients with CD enrolled in Prospective Registry in Inflammatory Bowel Disease Study at Massachusetts General Hospital (PRISM). VAT volume was measured from computed tomography using Aquarius 3D...
November 22, 2016: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/27882354/bcl-2-associated-athanogene-3-protects-the-heart-from-ischemia-reperfusion-injury
#6
Feifei Su, Valerie D Myers, Tijana Knezevic, JuFang Wang, Erhe Gao, Muniswamy Madesh, Farzaneh G Tahrir, Manish K Gupta, Jennifer Gordon, Joseph Rabinowitz, Frederick V Ramsey, Douglas G Tilley, Kamel Khalili, Joseph Y Cheung, Arthur M Feldman
Bcl-2-associated athanogene 3 (BAG3) is an evolutionarily conserved protein expressed at high levels in the heart and the vasculature and in many cancers. While altered BAG3 expression has been associated with cardiac dysfunction, its role in ischemia/reperfusion (I/R) is unknown. To test the hypothesis that BAG3 protects the heart from reperfusion injury, in vivo cardiac function was measured in hearts infected with either recombinant adeno-associated virus serotype 9-expressing (rAAV9-expressing) BAG3 or GFP and subjected to I/R...
November 17, 2016: JCI Insight
https://www.readbyqxmd.com/read/27878133/massive-pneumocephalus-and-pneumorrhachis-after-severe-skull-base-fracture
#7
Hosseinali Khalili, Amin Niakan, Fariborz Ghaffarpasand
No abstract text is available yet for this article.
October 2016: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/27874029/an-anti-tnf-%C3%AE-antibody-mimetic-to-treat-ocular-inflammation
#8
Hanieh Khalili, Richard W Lee, Peng T Khaw, Steve Brocchini, Andrew D Dick, David A Copland
Infliximab is an antibody that neutralizes TNF-α and is used principally by systemic administration to treat many inflammatory disorders. We prepared the antibody mimetic Fab-PEG-Fab (FpFinfliximab) for direct intravitreal injection to assess whether such formulations have biological activity and potential utility for ocular use. FpFinfliximab was designed to address side effects caused by antibody degradation and the presence of the Fc region. Surface plasmon resonance analysis indicated that infliximab and FpFinfliximab maintained binding affinity for both human and murine recombinant TNF-α...
November 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27871029/effects-of-cerebrolysin-on-functional-recovery-in-patients-with-severe-disability-after-traumatic-brain-injury-a-historical-cohort-study
#9
Hosseinali Khalili, Amin Niakan, Fariborz Ghaffarpasand
OBJECTIVE: To determine the effects of cerebrolysin on functional recovery in patients with severe disability after traumatic brain injury (TBI). METHODS: This was a retrospective cohort study being performed during a 2-year period in a level I trauma center in Southern Iran including all the adult patients (>16years) with severe disability (GOS of 2 and 3) 1-month after trauma. We excluded those with posttraumatic seizures and those with meningitis or current infections...
November 15, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27864657/erratum-to-vedolizumab-therapy-is-associated-with-an-improvement-in-sleep-quality-and-mood-in-inflammatory-bowel-diseases
#10
Betsy W Stevens, Nynke Z Borren, Gabriella Velonias, Grace Conway, Thom Cleland, Elizabeth Andrews, Hamed Khalili, John J Garber, Ramnik J Xavier, Vijay Yajnik, Ashwin N Ananthakrishnan
No abstract text is available yet for this article.
November 18, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27847695/combined-ketamine-tramadol-subcutaneous-wound-infiltration-for-multimodal-postoperative-analgesia-a-double-blinded-randomized-controlled-trial-after-renal-surgery
#11
Mohammad Reza Khajavi, Marzieh Navardi, Reza Shariat Moharari, Pejman Pourfakhr, Narjes Khalili, Farhad Etezadi, Farsad Imani
BACKGROUND: Pain is an important consideration after renal surgery. A multimodal approach to postoperative pain management could enhance analgesia by risking fewer side effects after surgery. OBJECTIVES: The aim of this study was to evaluate the clinical efficacy of the subcutaneous infiltration of ketamine and tramadol at the incision site to reduce postoperative pain. METHODS: Sixty-four patients between 18 and 80 years old who were scheduled for elective renal surgery were enrolled in a double-blind randomized controlled study...
October 2016: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/27843970/ascorbic-acid-in-septic-shock
#12
Hossein Khalili
No abstract text is available yet for this article.
October 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/27843963/comparative-evaluation-between-two-methods-of-induced-hypotension-with-infusion-of-remifentanil-and-labetalol-during-sinus-endoscopy
#13
Parvin Sajedi, Ali Rahimian, Gholamreza Khalili
OBJECTIVE: This study aimed to compare two methods of controlled hypotension using labetalol and remifentanil in terms of capability to create controlled hypotension and to investigate the obtained complications, and satisfaction rate of surgeon and patient during functional endoscopic sinus surgery. METHODS: In this prospective clinical trial, 62 patients underwent endoscopic sinus surgery in Al-Zahra and Ayatollah Kashani Hospitals of Isfahan were divided into two groups: in the first group, 20 mg bolus dose of labetalol and then infusion of it, at a rate of 0...
October 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/27830210/optic-nerve-glioma-with-complete-intraocular-extension
#14
Masoomeh Eghtedari, Seyede Fariba Fattahi, Naser Owji, Mohammad Javad Ashraf, Mohammad Reza Khalili, Bita Geramizadeh
PURPOSE: To present a rare presentation of optic nerve glioma (ONG) with total intraocular extension. METHODS: A 44-year-old man with a history of loss of vision since childhood and recent development of progressive disfiguring proptosis was referred. RESULTS: The vision in the affected eye was no light perception, and a proptosis of about 2-3 mm was present. Computed tomography and Magnetic Resonance Imaging (MRI) of brain/orbit showed a fusiform enlargement of the left optic nerve and total filling of vitreous cavity by a mass with high signal intensity in T2-weighted MRI...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27829526/sex-specific-incidence-rates-and-risk-factors-of-premature-cardiovascular-disease-a-long-term-follow-up-of-the-tehran-lipid-and-glucose-study
#15
Ali Eslami, Amirhossein Mozaffary, Arash Derakhshan, Fereidoun Azizi, Davood Khalili, Farzad Hadaegh
OBJECTIVES: To investigate the risk factors for premature cardiovascular disease (CVD) and to quantify their population attributable fractions (PAFs) among an Iranian population during a median follow-up of 12years. METHODS: A total of 2235 men and 3703 women, aged ≥30years, free of CVD at baseline were entered into the study. Premature CVD was defined as having a history of CVD events before the age of 55 and 65 for men and women, respectively. Multivariate Cox proportional hazard regression models were used to determine the risk factors associated with premature CVD events...
October 17, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27827978/a-prospective-study-of-different-types-of-dietary-fiber-and-risk-of-cardiovascular-disease-tehran-lipid-and-glucose-study
#16
Parvin Mirmiran, Zahra Bahadoran, Sajad Khalili Moghadam, Azita Zadeh Vakili, Fereidoun Azizi
BACKGROUND AND AIM: This study was designed to examine the hypothesis that dietary of intake different types of fiber could modify the risk of cardiovascular disease (CVD) in a large prospective cohort among Iranian adults. METHODS: In 2006-2008, we used a validated food frequency questionnaire to assess dietary fiber intake among 2295 health professionals with no previous history of heart disease. Subjects were subsequently followed until 2012 for incidence of CVD events...
November 7, 2016: Nutrients
https://www.readbyqxmd.com/read/27826942/retraction-note-to-diagnostic-investigations-of-canine-prostatitis-incidence-together-with-benign-prostate-hyperplasia-prostate-malignancies-and-biochemical-recurrence-in-high-risk-prostate-cancer-as-a-model-for-human-study
#17
Radmehr Shafiee, Alireza Shariat, Soheil Khalili, Hamed Zamankhan Malayeri, Aram Mokarizadeh, Ali Anissian, Mohammad Reza Hafezi Ahmadi, Ehsan Hosseini, Mostafa Naderafif, Siamak Mohsenzadeh, Mohammad Hosein Rasoulian, Reza Rezapour, Maryam Pourzaer
No abstract text is available yet for this article.
November 8, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27817082/retraction-note-to-urinary-parameters-predictive-and-electrolyte-disturbances-of-cisplatin-induced-acute-renal-associated-with-cancer-as-a-critical-target-of-the-chemotherapeutic-agent-in-patients-with-solid-tumors
#18
Behnam Pedram, Ahmad Taghavi Moghadam, Zahra Kamyabi-Moghaddam, Omid Mavedati, Babak Abbas Beigi, Adel Khodaei Sharabiyani, Ali Bashiri Dezfuli, Soheil Khalili, Ali Mohammad Bahrami, Alireza Nasoori
No abstract text is available yet for this article.
November 5, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27811627/provider-patient-and-practice-factors-shape-hepatitis-b-prevention-and-management-by-primary-care-providers
#19
Nizar A Mukhtar, Priya Kathpalia, Joan F Hilton, Gene Lau, Albert Yu, Kevin Grumbach, Tung T Nguyen, Daniel Chan, Mandana Khalili
GOALS: To evaluate provider knowledge, attitudes and barriers to hepatitis B virus (HBV) care and management practices across diverse primary care settings. BACKGROUND: Factors influencing adherence to recommended HBV screening and management guidelines are poorly defined. MATERIALS AND METHODS: Providers across various health care settings in San Francisco were surveyed. Multivariate analyses were used to identify factors associated with recommended HBV screening, vaccination, and disease monitoring...
November 2, 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27810077/chronic-myelogenous-leukemia-with-acquired-t-11-14-q13-q32-ccnd1-igh-a-case-report-and-literature-review
#20
M T Manda-Mapalo, P Khalili, D Quintana, I Rabinowitz, Q Y Zhang
Approximately 5-10% of chronic myeloid leukemia (CML) patients are found to have structural or numerical additional chromosomal abnormality (ACAs) in addition to the characteristic t(9;22)(q34;q11.2) BCR/ABL1 at the time of diagnosis. The prognostic significance of such additional chromosomal abnormalities has been controversial. Translocation t(11;14)(q13;q32) CCND1-IGH is typically associated with mantle cell lymphoma or a subset of plasma cell myeloma and is exceedingly rare in myeloid neoplasm. Here we report a unique case describing a patient found at diagnosis of chronic phase CML to have both the Philadelphia chromosome as well as t(11;14)-a rare cytogenetic combination...
October 2016: Cancer Genetics
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