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https://www.readbyqxmd.com/read/29685054/analysis-of-antigen-conservation-and-inactivation-of-gamma-irradiated-avian-influenza-virus-subtype-h9n2
#1
Bahareh Salehi, Farahnaz Motamedi-Sedeh, Omid Madadgar, Iraj Khalili, Arash Ghalyan Chi Langroudi, Hermann Unger, Viskam Wijewardana
Avian influenza (AI) A subtype H9N2 virus belongs to Orthomyxoviridae family and causes low-pathogenic disease AI. The use of gamma-irradiated viral antigens has been developed in the production of effective vaccines. In this research, LPAIV H9N2 strain, A/Chicken/IRN/Ghazvin/2001, was multiplied on SPF eggs and irradiated by a Nordian gamma cell instrument. Irradiated and non-irradiated AI virus (AIV) samples were titrated by EID50 method and hemagglutinin (HA) antigen was analyzed by HA test as the WHO pattern method...
April 24, 2018: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/29682908/tracking-disease-progression-non-invasively-in-duchenne-and-becker-muscular-dystrophies
#2
Pietro Spitali, Kristina Hettne, Roula Tsonaka, Mohammed Charrout, Janneke van den Bergen, Zaïda Koeks, Hermien E Kan, Melissa T Hooijmans, Andreas Roos, Volker Straub, Francesco Muntoni, Cristina Al-Khalili-Szigyarto, Marleen J A Koel-Simmelink, Charlotte E Teunissen, Hanns Lochmüller, Erik H Niks, Annemieke Aartsma-Rus
BACKGROUND: Analysis of muscle biopsies allowed to characterize the pathophysiological changes of Duchenne and Becker muscular dystrophies (D/BMD) leading to the clinical phenotype. Muscle tissue is often investigated during interventional dose finding studies to show in situ proof of concept and pharmacodynamics effect of the tested drug. Less invasive readouts are needed to objectively monitor patients' health status, muscle quality, and response to treatment. The identification of serum biomarkers correlating with clinical function and able to anticipate functional scales is particularly needed for personalized patient management and to support drug development programs...
April 16, 2018: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29675483/fresh-versus-frozen-embryo-transfer-after-gonadotropin-releasing-hormone-agonist-trigger-in-gonadotropin-releasing-hormone-antagonist-cycles-among-high-responder-women-a-randomized-multi-center-study
#3
Abbas Aflatoonian, Mahnaz Mansoori-Torshizi, Maryam Farid Mojtahedi, Behrouz Aflatoonian, Mohammaad Ali Khalili, Mohammad Hossein Amir-Arjmand, Mehrdad Soleimani, Nastaran Aflatoonian, Homa Oskouian, Nasim Tabibnejad, Peter Humaidan
Background: The use of embryo cryopreservation excludes the possible detrimental effects of ovarian stimulation on the endometrium, and higher reproductive outcomes following this policy have been reported. Moreover, gonadotropin-releasing hormone agonist trigger in gonadotropin-releasing hormone (GnRH) antagonist cycles as a substitute for standard human chorionic gonadotropin trigger, minimizes the risk of ovarian hyperstimulation syndrome (OHSS) in fresh as well as frozen embryo transfer cycles (FET)...
January 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29673662/the-influence-of-ovarian-hyperstimulation-drugs-on-morphometry-and-morphology-of-human-oocytes-in-icsi-program
#4
Fatemeh Taheri, Arezoo Alemzadeh Mehrizi, Mohammad Ali Khalili, Iman Halvaei
OBJECTIVE: To compare the influences of controlled ovarian hyperstimulation (COH) drugs using recombinant follicular stimulating hormone (rFSH) versus human menopausal gonadotropins (hMG) on morphometry and morphology of MII oocytes in ICSI cycles. MATERIALS AND METHODS: In this prospective study, 363 MII oocytes from 50 ICSI cycles with male factor infertility were evaluated. The patients were divided into two groups according to the protocols of COH: I- rFSH and II- hMG...
April 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29663355/microbial-decomposers-not-constrained-by-climate-history-along-a-mediterranean-climate-gradient-in-southern-california
#5
Nameer R Baker, Banafshe Khalili, Jennifer B H Martiny, Steven D Allison
Microbial decomposers mediate the return of CO2 to the atmosphere by producing extracellular enzymes to degrade complex plant polymers, making plant carbon available for metabolism. Determining if and how these decomposer communities are constrained in their ability to degrade plant litter is necessary for predicting how carbon cycling will be affected by future climate change. We analyzed mass loss, litter chemistry, microbial biomass, extracellular enzyme activities, and enzyme temperature sensitivities in grassland litter transplanted along a Mediterranean climate gradient in southern California...
April 17, 2018: Ecology
https://www.readbyqxmd.com/read/29648906/the-effects-of-a-community-based-lifestyle-intervention-on-metabolic-syndrome-and-its-components-in-adolescents-findings-of-a-decade-follow-up
#6
Parisa Amiri, Sara Jalali-Farahani, Hasti Masihay Akbar, Leila Cheraghi, Davood Khalili, Amirabbas Momenan, Parvin Mirmiran, Arash Ghanbarian, Mehdi Hedayati, Firoozeh Hosseini-Esfahani, Fereidoun Azizi
BACKGROUND: The increasing prevalence of metabolic syndrome (MetS) in childhood makes lifestyle interventions imperative during adolescence. This study aimed to assess the effects of a community-based lifestyle intervention on MetS and its components in adolescents. METHODS: Adolescents, based on their residential area were categorized into three groups: complete intervention (residing in the intervention area at baseline and during all follow-ups), incomplete intervention (residing in either the intervention or control areas and were in transition between these two areas), and control group (residing in the control area at baseline and throughout all follow-ups)...
April 12, 2018: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29644240/consanguineous-marriage-as-a-risk-factor-for-developing-keratoconus
#7
Hossein Jamali, Vahid Beigi, Ali Sadeghi-Sarvestani
Heredity plays an important role in keratoconus (KC). Consanguineous marriage (CM) can affect the transmission of recessively inherited conditions. We aimed to investigate the role of consanguineous marriage in the development of KC. This study included two groups: the first group comprised 415 patients who underwent surgery for KC for the first time at Khalili University Hospital (Shiraz, Iran), between 2010 and 2014; the second group comprised 415 healthy individuals who served as age- and sex-matched controls for the patient group...
2018: Medical Hypothesis, Discovery and Innovation in Ophthalmology
https://www.readbyqxmd.com/read/29627821/global-scientific-production-on-illicit-drug-addiction-a-two-decade-analysis
#8
Malahat Khalili, Afarin Rahimi-Movaghar, Behrang Shadloo, Ramin Mojtabai, Karl Mann, Masoumeh Amin-Esmaeili
AIMS: Addiction science has made great progress in the past decades. We conducted a scientometric study in order to quantify the number of publications and the growth rate globally, regionally, and at country levels. METHODS: In October 2015, we searched the Scopus database using the general keywords of addiction or drug-use disorders combined with specific terms regarding 4 groups of illicit drugs - cannabis, opioids, cocaine, and other stimulants or hallucinogens...
April 6, 2018: European Addiction Research
https://www.readbyqxmd.com/read/29623675/abdominal-imaging-findings-in-adult-patients-with-fontan-circulation
#9
REVIEW
Tae-Hyung Kim, Hyun Kyung Yang, Hyun-Jung Jang, Shi-Joon Yoo, Korosh Khalili, Tae Kyoung Kim
The Fontan procedures, designed to treat paediatric patients with functional single ventricles, have markedly improved the patient's survival into adulthood. The physiology of the Fontan circuit inevitably increases systemic venous pressure, which may lead to multi-system organ failure in the long-term follow-up. Fontan-associated liver disease (FALD) can progress to liver cirrhosis with signs of portal hypertension. Focal nodular hyperplasia-like nodules commonly develop in FALD. Imaging surveillance is often performed to monitor the progression of FALD and to detect hepatocellular carcinoma, which infrequently develops in FALD...
April 5, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29620794/systematic-review-with-meta-analysis-association-between-acetaminophen-and-nonsteroidal-anti-inflammatory-drugs-nsaids-and-risk-of-crohn-s-disease-and-ulcerative-colitis-exacerbation
#10
REVIEW
O O Moninuola, W Milligan, P Lochhead, H Khalili
BACKGROUND: Unlike acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs) have generally been thought to be associated with increased risk of IBD exacerbation. AIM: To carry out a systematic review and meta-analysis of previous studies examining the association between acetaminophen and NSAIDs including cyclooxygenase (COX-2) inhibitors use, and risk of Crohn's disease (CD) and ulcerative colitis (UC) exacerbation. METHODS: We identified published manuscripts and abstracts through 1 March 2017 by systematic search of Medline, Embase, Cochrane and other trial registries...
April 5, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29610507/vedolizumab-as-a-novel-treatment-for-refractory-collagenous-colitis-a-case-report
#11
Kelly C Cushing, Mari Mino-Kenudson, John Garber, Paul Lochhead, Hamed Khalili
No abstract text is available yet for this article.
April 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29610094/relative-ability-of-wedge-coupled-piezoelectric-and-meander-coil-emat-probes-to-generate-single-mode-lamb-waves
#12
Pouyan Khalili, Peter Cawley
Ultrasonic guided waves are used extensively when checking for defects in petrochemical and other industries and are mostly generated using piezoelectric transducers on an angled wedge or electromagnetic acoustic transducers (EMATs) in different configurations. Low-frequency inspection allows for long-distance propagation, but it is best suited for detecting relatively large defects, while at higher frequencies, the presence of multiple wave modes limit defect detectability, so achieving practical single Lamb mode excitation via careful transduction is very beneficial...
April 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29599296/relationship-between-metabolic-syndrome-alanine-aminotransferase-levels-and-liver-disease-severity-in-a-multiethnic-north-american-cohort-with-chronic-hepatitis-b
#13
Mandana Khalili, Margaret C Shuhart, Manuel Lombardero, Jordan J Feld, David E Kleiner, Raymond T Chung, Norah A Terrault, Mauricio Lisker-Melman, Arun Sanyal, Anna S Lok
OBJECTIVE: Metabolic syndrome (MS) is prevalent and is associated with adverse outcomes of liver disease. We evaluated the prevalence of MS and its influence on alanine aminotransferase (ALT) levels and fibrosis, as estimated by the aspartate aminotransferase-to-platelet ratio index (APRI), in a large, multiethnic North American cohort with chronic hepatitis B (HBV) infection. RESEARCH DESIGN AND METHODS: Adults with chronic HBV from 21 centers within the U.S. and Canada were evaluated at baseline and for up to 5 years (median 3...
March 29, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29595080/characterization-of-integrons-extended-spectrum-%C3%AE-lactamases-ampc-cephalosporinase-quinolone-resistance-and-molecular-typing-of-shigella-spp-from-iran
#14
Sajjad Zamanlou, Mohammad Ahangarzadeh Rezaee, Mohammad Aghazadeh, Reza Ghotaslou, Farhad Babaie, Younes Khalili
INTRODUCTION: The wide distribution of extended-spectrum β-lactamase (ESBL) producing Shigella spp., along with the emergence of fluoroquinolone resistant isolates, is a serious threat to public health, posing a new challenge for the effective treatment of shigellosis. The purpose of this study was to determine the level of antimicrobial resistance, the presence of genes encoding resistance to cephalosporins, and plasmid-mediated quinolone resistance (PMQR) among the clinical isolates of Shigella spp...
March 29, 2018: Infectious Diseases
https://www.readbyqxmd.com/read/29579345/the-effects-of-prebiotic-supplementation-on-weight-gain-diarrhoea-constipation-fever-and-respiratory-tract-infections-in-the-first-year-of-life
#15
Iraj Shahramian, Gholamreza Kalvandi, Hazhir Javaherizadeh, Manijeh Khalili, Noor Mohammad Noori, Mojtaba Delaramnasab, Ali Bazi
AIM: This study was conducted to evaluate the effect of prebiotics on some common clinical ailments in healthy term infants. METHODS: Sixty healthy-term, breastfed (BF) infants were included. Along with these infants, 120 healthy-term formula-fed infants were randomly assigned to either the prebiotic formula (PF, n = 60) or regular formula (RF, n = 60) groups. Ready-to-use prebiotic-supplemented formula containing galacto-oligosaccharides and polydextrose (ratio 1:1) was used...
March 26, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29572700/impact-of-the-erineum-strain-of-colomerus-vitis-acari-eriophyidae-on-the-development-of-plants-of-grapevine-cultivars-of-iran
#16
Saeid Javadi Khederi, Mohammad Khanjani, Mansur Gholami, Enrico de Lillo
The present experiment was aimed at determining the influence of the grape erineum strain of Colomerus vitis (GEM) (Acari: Eriophyidae) on responses of local grapevine cultivars. GEM was applied at five density levels to each of five cultivars, i.e. Shahani, Sahebi Uroomie, Khalili Bovanat, Rishbaba and Sezdang Ghalat (listed from early to late grape ripening). The experiment was performed in a full factorial design (12 replicates each) and effects of the mite on the relative content of leaf chlorophyll, internode and cane length, leaf area and weight, number and size of the erinea, and percentage of leaves with erinea were investigated...
March 23, 2018: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/29565358/a-lithium-oxygen-battery-with-a-long-cycle-life-in-an-air-like-atmosphere
#17
Mohammad Asadi, Baharak Sayahpour, Pedram Abbasi, Anh T Ngo, Klas Karis, Jacob R Jokisaari, Cong Liu, Badri Narayanan, Marc Gerard, Poya Yasaei, Xuan Hu, Arijita Mukherjee, Kah Chun Lau, Rajeev S Assary, Fatemeh Khalili-Araghi, Robert F Klie, Larry A Curtiss, Amin Salehi-Khojin
Lithium-air batteries are considered to be a potential alternative to lithium-ion batteries for transportation applications, owing to their high theoretical specific energy. So far, however, such systems have been largely restricted to pure oxygen environments (lithium-oxygen batteries) and have a limited cycle life owing to side reactions involving the cathode, anode and electrolyte. In the presence of nitrogen, carbon dioxide and water vapour, these side reactions can become even more complex. Moreover, because of the need to store oxygen, the volumetric energy densities of lithium-oxygen systems may be too small for practical applications...
March 21, 2018: Nature
https://www.readbyqxmd.com/read/29564413/the-effects-of-microwave-radiation-on-rabbit-s-retina
#18
Mohammad R Talebnejad, Ali Sadeghi-Sarvestani, M Hossein Nowroozzadeh, Seyed Mohammad J Mortazavi, Abbas Alighanbari, Mohammad R Khalili
Purpose: Mobile cell phones are used extensively these days, and their microwave (MW) radiation has been shown to affect the eye. The purpose of the present study was to evaluate the effects of MW radiation on rabbit retina. Methods: This experimental study (concluded in 2015) was conducted on 40 adult white New Zealand rabbits. A Global System for Mobile Communications (GSM) cell phone simulator was used for MW irradiation. The rabbits were randomized into five groups (8 in each) and treated as follows: Group 1: no irradiation (sham); Group 2: irradiation at 10 cm for 1 day; Group 3: irradiation at 30 cm for 1 day; Group 4: irradiation at 10 cm for 3 days; and Group 5: irradiation at 30 cm for 3 days...
March 2018: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/29563602/the-burden-of-statin-therapy-based-on-acc-aha-and-ncep-atp-iii-guidelines-an-iranian-survey-of-non-communicable-diseases-risk-factors
#19
Samaneh Asgari, Hengameh Abdi, Alireza Mahdavi Hezaveh, Alireza Moghisi, Koorosh Etemad, Hassan Riahi Beni, Davood Khalili
To compare the burden of statin therapy according to the Third Adult Treatment Panel (ATP-III) and the American College of Cardiology/American Heart Association (ACC/AHA) guidelines the Survey of Risk Factors of Non-Communicable Disease (SuRFNCD)-2011of Iran was used. A survey analysis associated with sex and age categorization was run. Of total 3496 persons (1322 men) aged 40-70 years, based on the ACC/AHA guidelines, about 46.5% were eligible to receive moderate- to high-intensity statin therapy. Based on the ATP-III guidelines, 17...
March 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29560137/surgical-outcome-of-conjunctival-rotational-autograft-mitomycin-c-mmc-versus-free-conjunctival-autograft-mmc-for-pterygium-removal-a-randomized-clinical-trial
#20
Shahram Bamdad, Anis Shamsi Kooshki, Masoud Yasemi
Background: Pterygium is a common degenerative eye disease. Despite various surgical methods to treat pterygium, recurrence is the main complication. The main issue is finding a surgical method with the lowest recurrence. Objective: to compare the complications, recurrence rate and the cosmetic effects of two surgical techniques, namely conjunctival rotation autograft (CRA) and conjunctival autograft (CA), in treating pterygium. Methods: This randomized clinical trial was conducted at Khalili Hospital in Shiraz, Iran, from January to August 2015...
December 2017: Electronic Physician
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