Deshayne B Fell, Margaret Russell, Stephen G Fung, Sarah Swayze, Hannah Chung, Sarah A Buchan, Weston Roda, Christa Smolarchuk, Kumanan Wilson, Natasha Crowcroft, Kevin L Schwartz, Jonathan B Gubbay, Allison McGeer, Marek Smieja, David C Richardson, Kevin Katz, George Zahariadis, Aaron Campigotto, Samira Mubareka, Dayre McNally, Timothy Karnauchow, Nathan Zelyas, Lawrence W Svenson, Jeffrey C Kwong
BACKGROUND: Randomized trials conducted in low- and middle-income settings demonstrated efficacy of influenza vaccination during pregnancy against influenza infection among infants <6 months of age. However, vaccine effectiveness (VE) estimates from settings with different population characteristics and influenza seasonality remain limited. METHODS: We conducted a test-negative study in Ontario, Canada. All influenza virus tests among infants <6 months from 2010-2019 were identified and linked with health databases to ascertain information on maternal-infant dyads...
November 29, 2023: Journal of Infectious Diseases