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Influenza during pregnancy

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https://www.readbyqxmd.com/read/29445450/prevention-of-influenza-related-illness-in-young-infants-by-maternal-vaccination-during-pregnancy
#1
REVIEW
Marta C Nunes, Shabir A Madhi
The influenza virus circulates yearly and causes global epidemics. Influenza infection affects all age groups and causes mild to severe illness, and young infants are at particular risk for serious disease. The most effective measure to prevent influenza disease is vaccination; however, no vaccine is licensed for use in infants younger than 6 months old. Thus, there is a crucial need for other preventive strategies in this high-risk age group. Influenza vaccination during pregnancy protects both the mothers and the young infants against influenza infection...
2018: F1000Research
https://www.readbyqxmd.com/read/29417364/maternal-care-providers-barriers-regarding-influenza-and-pertussis-vaccination-during-pregnancy-in-catalonia-spain
#2
Luz Maria Vilca, Cristina Martínez, Miriam Burballa, Magda Campins
Objective Maternal care providers (MCPs), obstetrician-gynaecologists and midwives are uniquely placed to increase maternal vaccination acceptance. We aimed to assess their knowledge, attitudes and practices regarding influenza and pertussis vaccination during pregnancy. Methods We conducted an online survey among MCPs working at "Attention to Sexual and Reproductive Health" (ASSIR) Units in Catalonia region. The survey included questions about current recommendations of influenza and pertussis immunization during pregnancy, reasons for not routinely recommending vaccination and several strategies to increase vaccination uptake...
February 7, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29400082/administration-rates-of-the-tdap-vaccine-in-obstetric-patients
#3
Jamie Koerner, Alicia B Forinash, Abigail M Yancey, Jessica Brinkmeyer, Spencer Dingman, Collin Miller, Judy Thompson, Laura Bergin, Julia D López, Amy Ravin
BACKGROUND: Infants younger than 6 months of age are at high risk for contracting pertussis because of not being fully vaccinated. The Advisory Committee on Immunization Practices (ACIP) recommends vaccinating all pregnant women with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) between 27 and 36 weeks to offer passive immunity to the infant to help protect them until they are able to receive the full pertussis series. OBJECTIVE: To assess and compare compliance with the 2013 ACIP recommendation of vaccinating pregnant women with Tdap at 27 to 36 weeks' gestation in 2 obstetric clinics...
February 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29390149/cord-blood-anti-parasite-il-10-as-risk-marker-for-compromised-vaccine-immunogenicity-in-early-childhood
#4
Indu Malhotra, A Desiree LaBeaud, Nathan Morris, Maxim McKibben, Peter Mungai, Eric Muchiri, Christopher L King, Charles H King
Background: Antenatal exposure to parasites can affect infants' subsequent responses to vaccination. The present study investigated how maternal prenatal infections and newborns' anti-parasite cytokine profiles relate to IgG responses to standard vaccination during infancy. Methods: 450 Kenyan women were tested for parasitic infections during pregnancy. Their newborns' responses to malaria, schistosome, and filaria antigens were assessed in cord blood (CB) lymphocytes...
January 30, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29388196/vaccines-for-preventing-influenza-in-healthy-adults
#5
REVIEW
Vittorio Demicheli, Tom Jefferson, Eliana Ferroni, Alessandro Rivetti, Carlo Di Pietrantonj
BACKGROUND: The consequences of influenza in adults are mainly time off work. Vaccination of pregnant women is recommended internationally. This is an update of a review published in 2014. Future updates of this review will be made only when new trials or vaccines become available. Observational data included in previous versions of the review have been retained for historical reasons but have not been updated due to their lack of influence on the review conclusions. OBJECTIVES: To assess the effects (efficacy, effectiveness, and harm) of vaccines against influenza in healthy adults, including pregnant women...
February 1, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29320882/the-impact-of-influenza-virus-infection-in-pregnancy
#6
Lucy K Somerville, Kerri Basile, Dominic E Dwyer, Jen Kok
Data from previous seasonal epidemics and pandemics have confirmed that pregnant women are at increased risk for severe influenza virus infection. Complications including fetal loss, higher rates of hospitalization and maternal death are most notable during the late gestational period. Antiviral therapy and influenza vaccination are recommended in pregnant women as both are effective and safe. This review discusses the epidemiology, pathophysiology, treatment and prevention of influenza virus infection in pregnancy, with a focus on recent developments...
January 11, 2018: Future Microbiology
https://www.readbyqxmd.com/read/29277629/patterns-and-correlates-of-cervical-cancer-screening-initiation-in-a-large-integrated-healthcare-system
#7
Tracy A Becerra-Culqui, Neal M Lonky, Qiaoling Chen, Chun R Chao
BACKGROUND: The latest 2012 United States Preventive Services Task Force cervical cancer screening guidelines recommended screening initiation at age 21 years. Little is known about the cervical cancer screening initiation practices in the community, and whether there are critical gaps with respect to adherence to current clinical guidelines. Despite an overall decline in cervical cancer incidence across women of all ages, the incidence rate has not declined among 24-25 year-olds between 2000 (2...
December 22, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29232882/seasonal-influenza-vaccine-acceptance-among-pregnant-women-in-zhejiang-province-china-evidence-based-on-health-belief-model
#8
Yu Hu, Ying Wang, Hui Liang, Yaping Chen
Background: Reasons for acceptance of seasonal influenza vaccine (SIV) vaccination among pregnant women in China are poorly understood. We assessed the intention to accept SIV among pregnant women in Zhejiang province, by using a self-administrated structured questionnaire developed on the basis of health belief model (HBM). Methods: From 1 January to 31 March 2014, pregnant women with ≥12 gestational weeks who attended antenatal clinics (ANCs) at public hospitals in 6 out of 90 districts were surveyed using a self-administered questionnaire that covered knowledge, attitudes, and beliefs related to SIV vaccination and influenza infection...
December 11, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29221347/safe-administration-of-intrapleural-alteplase-during-pregnancy
#9
Heather Torbic, Hanine Inaty, Siva Raja, Humberto Choi
Instillation of intrapleural (IP) fibrinolytics has been used in patients with complicated parapneumonic pleural effusions to improve fluid drainage and decrease the need for surgical intervention. However, clinical trials have not included certain special populations such as pregnant females and there are currently no published case reports of this practice in this group. We describe the case of a 35-year-old female, G2P1 at 32 weeks of gestation, with a complicated pleural effusion due to influenza pneumonia with superimposed bacterial pneumonia...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29188070/the-first-case-report-of-septic-abortion-resulting-from-%C3%AE-lactamase-negative-ampicillin-resistant-non-typeable-haemophilus-influenzae-infection
#10
Hiroaki Baba, Risako Kakuta, Hasumi Tomita, Minako Miyazoe, Masatoshi Saito, Chihiro Oe, Noriomi Ishibashi, Misa Sogi, Kengo Oshima, Tetsuji Aoyagi, Yoshiaki Gu, Makiko Yoshida, Koichi Tokuda, Shiro Endo, Hisakazu Yano, Mitsuo Kaku
Introduction. This is the first case report of septic abortion due to β-lactamase-negative ampicillin-resistant (BLNAR) non-typeable Haemophilus influenzae infection. In Japan, BLNAR H. influenzae is widespread and has become a clinical concern, especially in paediatrics and otolaryngology, but H. influenzae has not been previously recognized as a causative agent of obstetric or gynaecological infection. Case presentation. A 31-year-old pregnant woman presented at 17 weeks and 6 days of gestation with a high fever; she was admitted with a diagnosis of threatened premature delivery...
October 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29176767/h1n1-influenza-virus-infection-results-in-adverse-pregnancy-outcomes-by-disrupting-tissue-specific-hormonal-regulation
#11
Elizabeth Q Littauer, E Stein Esser, Olivia Q Antao, Elena V Vassilieva, Richard W Compans, Ioanna Skountzou
Increased susceptibility to influenza virus infection during pregnancy has been attributed to immunological changes occurring before and during gestation in order to "tolerate" the developing fetus. These systemic changes are most often characterized by a suppression of cell-mediated immunity and elevation of humoral immune responses referred to as the Th1-Th2 shift. However, the underlying mechanisms which increase pregnant mothers' risk following influenza virus infection have not been fully elucidated. We used pregnant BALB/c mice during mid- to late gestation to determine the impact of a sub-lethal infection with A/Brisbane/59/07 H1N1 seasonal influenza virus on completion of gestation...
November 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/29149524/a-systematic-review-and-meta-analysis-of-fetal-outcomes-following-the-administration-of-influenza-a-h1n1-vaccination-during-pregnancy
#12
REVIEW
Chuan Zhang, Xiaodong Wang, Dan Liu, Lingli Zhang, Xin Sun
BACKGROUND: Pregnant women were identified as a population of priority for vaccination during the H1N1 influenza pandemic outbreak in 2009. OBJECTIVES: To assess adverse fetal outcomes following the administration of H1N1 pandemic vaccination during pregnancy. SEARCH STRATEGY: PubMed, Embase, and Cochrane Library were searched up to January 2017. SELECTION CRITERIA: Cohort studies investigating fetal outcomes after H1N1 influenza vaccination during pregnancy were eligible...
November 17, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29145441/distinct-t-and-nk-cell-populations-may-serve-as-immune-correlates-of-protection-against-symptomatic-pandemic-influenza-a-h1n1-virus-infection-during-pregnancy
#13
Miloje Savic, Jennifer L Dembinski, Ida Laake, Olav Hungnes, Rebecca Cox, Fredrik Oftung, Lill Trogstad, Siri Mjaaland
Maternal influenza infection during pregnancy is associated with increased risk of morbidity and mortality. However, the link between the anti-influenza immune responses and health-related risks during infection is not well understood. We have analyzed memory T and NK cell mediated immunity (CMI) responses in pandemic influenza A(H1N1)pdm09 (pdm09) virus infected non-vaccinated pregnant women participating in the Norwegian Influenza Pregnancy Cohort (NorFlu). The cohort includes information on immunization, self-reported health and disease status, and biological samples (plasma and PBMC)...
2017: PloS One
https://www.readbyqxmd.com/read/29139107/antenatal-influenza-and-pertussis-vaccine-uptake-among-aboriginal-mothers-in-western-australia
#14
Kennia Lotter, Annette K Regan, Tyra Thomas, Paul V Effler, Donna B Mak
BACKGROUND: Antenatal influenza and pertussis vaccination prevent serious disease in mothers and infants. Aboriginal individuals are at increased risk of infection yet little is known about vaccine coverage among Aboriginal mothers. AIMS: To estimate the uptake of influenza and pertussis vaccination among pregnant Aboriginal women in Western Australia and identify barriers and enablers to vaccination. MATERIALS AND METHODS: Four hundred Aboriginal women, aged ≥18 years, who gave birth to a live infant between April and October 2015, were randomly selected and invited to participate in telephone interviews...
November 14, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29120017/review-of-maternal-immunisation-during-pregnancy-focus-on-pertussis-and-influenza
#15
Géraldine Blanchard-Rohner, Christiane Eberhardt
Seasonal influenza and pertussis infections are known to be significant causes of morbidity and mortality in neonates and infants worldwide. Influenza has also been associated with severe complications in pregnant women and after delivery. The most efficient and safe strategy to protect mothers and their offspring is maternal immunisation during pregnancy. The maternal antibodies thus acquired are transferred to the fetus as of the second trimester and confer passive immunity until the first infant immunisations...
November 9, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29108905/-maternal-deaths-due-to-infectious-cause-results-from-the-french-confidential-enquiry-into-maternal-deaths-2010-2012
#16
A Rigouzzo, V Tessier, L Zieleskiewicz
Over the period 2010-2012, maternal mortality from infectious causes accounted for 5% of maternal deaths by direct causes and 16% of maternal deaths by indirect causes. Among the 22 deaths caused by infection occurred during this period, 6 deaths were attributed to direct causes from genital tract origin, confirming thus the decrease in direct maternal deaths by infection during the last ten years. On the contrary, indirect maternal deaths by infection, from extragenital origin, doubled during the same period, with 16 deaths in the last triennium, dominated by winter respiratory infections, particularly influenza: the 2009-2010 influenza A (H1N1) virus pandemic was the leading cause of indirect maternal mortality by infection during the studied period...
November 3, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29073129/receipt-of-selected-preventive-health-services-for-women-and-men-of-reproductive-age-united-states-2011-2013
#17
Karen Pazol, Cheryl L Robbins, Lindsey I Black, Katherine A Ahrens, Kimberly Daniels, Anjani Chandra, Anjel Vahratian, Lorrie E Gavin
PROBLEM/CONDITION: Receipt of key preventive health services among women and men of reproductive age (i.e., 15-44 years) can help them achieve their desired number and spacing of healthy children and improve their overall health. The 2014 publication Providing Quality Family Planning Services: Recommendations of CDC and the U.S. Office of Population Affairs (QFP) establishes standards for providing a core set of preventive services to promote these goals. These services include contraceptive care for persons seeking to prevent or delay pregnancy, pregnancy testing and counseling, basic infertility services for those seeking to achieve pregnancy, sexually transmitted disease (STD) services, and other preconception care and related preventive health services...
October 27, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29048989/vaccination-in-pregnancy-attitudes-of-nurses-midwives-and-health-visitors-in-england
#18
Bhavita Vishram, Louise Letley, Albert Jan Van Hoek, Louise Silverton, Helen Donovan, Cheryll Adams, David Green, Angela Edwards, Joanne Yarwood, Helen Bedford, Gayatri Amirthalingam, Helen Campbell
OBJECTIVE: To examine amongst healthcare professionals in England; knowledge of vaccinations in pregnancy, their perceived roles in these programmes and whether they recommend scheduled vaccines to pregnant women. DESIGN: Cross sectional survey (online questionnaire) Setting: Healthcare workers in contact with pregnant women in England. PARTICIPANTS: The survey analysis included 3441 healthcare workers who had been surveyed during May to August 2015...
October 19, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29037576/pertussis-seroepidemiology-in-women-and-their-infants-in-sarlahi-district-nepal
#19
Michelle M Hughes, Janet A Englund, Kathryn Edwards, Sandra Yoder, James M Tielsch, Mark Steinhoff, Subarna K Khatry, Steven C LeClerq, Joanne Katz
BACKGROUND: Infants are at greatest risk for pertussis morbidity and mortality. Maternal vaccination during pregnancy has been shown to prevent pertussis in young infants in high- and middle-income countries. However, data on the levels of maternal pertussis antibodies and the efficiency of transplacental transfer in low-income South Asian settings are limited. OBJECTIVE: To estimate the prevalence of maternal pertussis antibodies and the efficiency of transplacental transfer in rural southern Nepal...
October 13, 2017: Vaccine
https://www.readbyqxmd.com/read/29029127/antibody-kinetics-and-response-to-routine-vaccinations-in-infants-born-to-women-who-received-an-investigational-trivalent-group-b-streptococcus-polysaccharide-crm197-conjugate-vaccine-during-pregnancy
#20
Shabir A Madhi, Anthonet Koen, Clare L Cutland, Lisa Jose, Niresha Govender, Frederick Wittke, Morounfolu Olugbosi, Ajoke Sobanjo-Ter Meulen, Sherryl Baker, Peter M Dull, Vas Narasimhan, Karen Slobod
Background: Maternal vaccination against group B Streptococcus (GBS) might provide protection against invasive GBS disease in infants. We investigated the kinetics of transplacentally transferred GBS serotype-specific capsular antibodies in the infants and their immune response to diphtheria toxoid and pneumococcal vaccination. Methods: This phase 1b/2, observer-blind, single-center study (NCT01193920) enrolled infants born to women previously randomized (1:1:1:1) to receive either GBS vaccine at dosages of 0...
November 13, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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