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Influenza during pregnancy

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https://www.readbyqxmd.com/read/28398678/maternal-immunization
#1
Helen Y Chu, Janet A Englund
Pregnant women, neonates, and infants are at higher risk for severe infections due to vaccine-preventable diseases. Very young infants rarely respond well to vaccination due to poor immunogenicity and interference from maternal antibody. Maternal immunization protects the mother and fetus from disease and protects the infant through transplacental antibody transfer through the first 6 months of life. Currently, immunizations routinely recommended during pregnancy include inactivated influenza, tetanus toxoid, and acellular pertussis vaccines...
March 15, 2017: Birth Defects Res
https://www.readbyqxmd.com/read/28369198/contribution-of-serology-assays-in-the-evaluation-of-influenza-virus-infection-rates-and-vaccine-efficacy-in-pregnant-women-report-from-randomized-controlled-trials
#2
Shabir A Madhi, Marta Nunes, Adriana Weinberg, Locadiah Kuwanda, Andrea Hugo, Stephanie Jones, Nadia van Niekerk, Justin R Ortiz, Kathleen M Neuzil, Keith P Klugman, Eric A F Simoes, Clare L Cutland
Background: The utility of serological testing to evaluate vaccine efficacy of seasonal inactivated influenza vaccine (IIV) is controversial. We aimed to evaluate the efficacy of IIV against serologically-diagnosed influenza infection (SDI), and reverse-transcription polymerase chain reaction confirmed influenza illness (PCR-CI) in women vaccinated during pregnancy. Methods: We undertook a post-hoc analysis of two randomized clinical trials evaluating IIV efficacy among HIV-uninfected and HIV-infected pregnant women...
March 21, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28348786/haemophilus-influenzae-type-a-as-a-cause-of-paediatric-septic-arthritis
#3
Joelle Thorgrimson, Marina Ulanova
INTRODUCTION: Incidence rates of invasive Haemophilus influenzae serotype b disease have decreased significantly since the introduction of the Hib vaccine; however, the rates in indigenous populations remain disproportionately high, specifically in the paediatric population. Additionally, with the decline of type b invasive infections, there has been a rebound in the incidence of invasive infections caused by other strains of H. influenzae, particularly serotype a. CASE PRESENTATION: We present a paediatric case of septic arthritis caused by H...
October 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28343772/report-of-the-who-technical-consultation-on-the-effect-of-maternal-influenza-and-influenza-vaccination-on-the-developing-fetus-montreal-canada-september-30-october-1-2015
#4
Deshayne B Fell, Zulfiqar A Bhutta, Jennifer A Hutcheon, Ruth A Karron, Marian Knight, Michael S Kramer, Arnold S Monto, Geeta K Swamy, Justin R Ortiz, David A Savitz
In 2012, the World Health Organization (WHO) released a position paper on influenza vaccination recommending that pregnant women have the highest priority for seasonal vaccination in countries where the initiation or expansion of influenza immunization programs is under consideration. Although the primary goal of the WHO recommendation is to prevent influenza illness in pregnant women, the potential benefits of maternal immunization in protecting young infants are also recognized. The extent to which maternal influenza vaccination may prevent adverse birth outcomes such as preterm birth or small-for-gestational-age birth, however, is unclear as available studies are in disagreement...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28341114/measuring-maternal-tdap-and-influenza-vaccination-rates-comparison-of-two-population-based-methods
#5
Ruth Koepke, Stephanie L Schauer, Jeffrey P Davis
Pregnant women are routinely recommended to receive Tdap and influenza vaccines to prevent disease and complications among mothers and newborns. Monitoring population trends in maternal vaccination is important in order to evaluate the implementation of these recommendations and to identify pockets of need. We present two methods for measuring maternal vaccination among a state population and discuss the strengths and drawbacks of each method. First, we matched maternal information from records of Wisconsin births during 2013-2015 with maternal vaccination records in the Wisconsin Immunization Registry...
March 21, 2017: Vaccine
https://www.readbyqxmd.com/read/28327032/newborns-not-at-raised-risk-if-flu-drugs-taken-in-pregnancy
#6
(no author information available yet)
There is no evidence to suggest an increased risk to newborns whose mothers take drugs to prevent or treat influenza during pregnancy, research suggests.
March 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28278407/influenza-vaccination-coverage-among-pregnant-indigenous-women-in-the-northern-territory-of-australia
#7
Sarah A Moberley, Jolie Lawrence, Vanessa Johnston, Ross M Andrews
Pregnant Aboriginal and Torres Strait Islander women are at particular risk of severe illness and high attack rates of influenza infection. In Australia, routine seasonal influenza vaccination is currently strongly recommended for all pregnant women and women planning pregnancy, and is provided free of charge for all pregnant women. We sought to determine vaccination coverage, describe the trends and characteristics associated with influenza vaccine uptake and determine the validity of self-reported influenza vaccination in a population of Indigenous pregnant women who were participants of a vaccine trial, prior to and during the 2009 H1N1 influenza pandemic...
September 30, 2016: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/28254223/seropositivity-of-influenza-a-h1ni-in-mothers-and-infants-following-maternal-vaccination-with-trivalent-seasonal-influenza-vaccine-after-the-2009-pandemic
#8
An-Shine Chao, Yao-Lung Chang, Anne Chao, Ting-Shu Wu, Lan-Yan Yang, Reyin Lian, Yhu-Chering Huang
OBJECTIVE: To assess H1N1 antibody titers between vaccinated and nonvaccinated maternal and cord blood sera after the 2009 pandemic. MATERIALS AND METHODS: Antibody titers were measured in maternal blood and cord sera from three groups of pregnant women in this prospective study. Group 1 comprised women who received a trivalent seasonal influenza vaccine before conception, Group 2 comprised women who received a single injection of monovalent H1N1 vaccine during pregnancy, and Group 3 comprised women who were nonvaccinated...
February 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28223865/knowledge-attitudes-beliefs-and-barriers-associated-with-the-uptake-of-influenza-vaccine-among-pregnant-women
#9
Ahmed Y Mayet, Ghadeer K Al-Shaikh, Hazem M Al-Mandeel, Nada A Alsaleh, Amani F Hamad
Objective: The purpose of the study was to assess the knowledge, attitudes, beliefs, and factors associated with the uptake of the influenza (flu) vaccination in women within Saudi Arabia during their pregnancy period. Methods: A cross-sectional prospective survey was conducted on 1085 pregnant women at the antenatal clinic over a period of 6 weeks with the provision of influenza vaccination. The questionnaire collected demographic and other data; it included 12 questions on their general knowledge and assessed their attitude toward influenza vaccination, and their awareness of vaccine risk and the potential benefits during pregnancy...
January 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28216380/a-population-based-analysis-of-predictors-of-influenza-vaccination-uptake-in-pregnant-women-the-effect-of-gestational-and-calendar-time
#10
Luz Maria Vilca, Aman Verma, David Buckeridge, Magda Campins
Pregnant women are vaccinated against influenza less frequently than other high-risk groups. To design effective vaccination strategies, we must understand how decisions regarding vaccination may vary by trimester and over vaccination campaigns. We used a Cox model indexed by calendar time to estimate the effect of gestational trimester and other factors on vaccination uptake in a large cohort of pregnant women in Catalonia (Spain) during 2008-09 to 2012-13 influenza vaccination campaigns. We analyzed 247,316 pregnancies...
February 16, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28214181/-adult-immunisation-general-points-hot-topics-and-perspectives
#11
P Loubet, O Launay
Vaccination in immunocompetent adult mainly concerns booster vaccination against diphtheria, tetanus, polio and pertussis. Some chronic diseases may also require the achievement of pneumococcal and influenza vaccines. In addition, from the age of 65, annual influenza vaccination as well as one dose of a live attenuated shingles vaccine between 64 and 75 years are recommended. Immunocompromised adults, due to the increased risk of serious infections responsible of significant morbidity and mortality, are particularly concerned by vaccination...
February 14, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28190746/birth-outcomes-for-australian-mother-infant-pairs-who-received-an-influenza-vaccine-during-pregnancy-2012-2014-the-flumum-study
#12
Lisa McHugh, Ross M Andrews, Stephen B Lambert, Kerri A Viney, Nicholas Wood, Kirsten P Perrett, Helen S Marshall, Peter Richmond, Kerry-Ann F O'Grady
INTRODUCTION: In Australia, influenza vaccination is recommended for all women who will be pregnant during the influenza season. Vaccine safety and effectiveness are key concerns and influencers of uptake for both vaccine providers and families. We assessed the safety of receiving an influenza vaccination during any trimester of pregnancy with respect to preterm births and infant birthweight. METHODS: We conducted a nested retrospective cohort study of 'FluMum' participants (2012-2014)...
February 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28178298/the-impact-of-prenatal-exposure-to-parasitic-infections-and-to-anthelminthic-treatment-on-antibody-responses-to-routine-immunisations-given-in-infancy-secondary-analysis-of-a-randomised-controlled-trial
#13
Stephen Nash, Alexander J Mentzer, Swaib A Lule, Dennison Kizito, Gaby Smits, Fiona R M van der Klis, Alison M Elliott
BACKGROUND: Chronic parasitic infections are associated with active immunomodulation which may include by-stander effects on unrelated antigens. It has been suggested that pre-natal exposure to parasitic infections in the mother impacts immunological development in the fetus and hence the offspring's response to vaccines, and that control of parasitic infection among pregnant women will therefore be beneficial. METHODOLOGY/PRINCIPAL FINDINGS: We used new data from the Entebbe Mother and Baby Study, a trial of anthelminthic treatment during pregnancy conducted in Uganda, to further investigate this hypothesis...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28137527/use-of-herbal-product-among-pregnant-women-in-turkey
#14
Aygül Kıssal, Ümran Çevik Güner, Döndü Batkın Ertürk
OBJECTIVE: This study was conducted to determine the herbal product use of pregnants as there is not adequate information relating to the rate of herbal product use during pregnancy in Turkey and what is thought about effects and side effects thereof. METHODS: It is a descriptive study consisted of 366 pregnants admitted to hospital for childbirth in gynaecology and obstetrics clinics of a public hospital or a university hospital. Data were collected with individual information form and question form of herbal product use in pregnancy...
February 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28073985/population-based-pertussis-incidence-and-risk-factors-in-infants-less-than-6-months-in-nepal
#15
Michelle M Hughes, Janet A Englund, Jane Kuypers, James M Tielsch, Subarna K Khatry, Laxman Shrestha, Steven C LeClerq, Mark Steinhoff, Joanne Katz
Background.: Pertussis is estimated to cause 2 percent of childhood deaths globally and is a growing public health problem in developed countries despite high vaccination coverage. Infants are at greatest risk of morbidity and mortality. Maternal vaccination during pregnancy may be effective to prevent pertussis in young infants, but population-based estimates of disease burden in infants are lacking, particularly in low-income countries. The objective of this study was to estimate the incidence of pertussis in infants less than 6 months of age in Sarlahi District, Nepal...
March 1, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28068918/seasonal-influenza-vaccination-in-pregnant-women-knowledge-attitudes-and-behaviors-in-italy
#16
Francesco Napolitano, Paola Napolitano, Italo Francesco Angelillo
BACKGROUND: The aims of this study were to assess the knowledge, attitudes, and behaviors towards seasonal influenza and its vaccination among pregnant women. METHODS: A cross-sectional survey was carried out among a sample of women in the second or third trimester of pregnancy in Italy. RESULTS: The 64.2% of the sample knew that the influenza is more dangerous for pregnant women. Women of older age, Italian, and who had a pregnancy at high-risk were more likely to have this knowledge...
January 9, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28062124/text-messages-for-influenza-vaccination-among-pregnant-women-a-randomized-controlled-trial
#17
Mark H Yudin, Niraj Mistry, Leanne R De Souza, Kate Besel, Vishal Patel, Sonia Blanco Mejia, Robyn Bernick, Victoria Ryan, Marcelo Urquia, Richard H Beigi, Michelle H Moniz, Michael Sgro
OBJECTIVE: To evaluate if text message reminders increase the likelihood of receiving the influenza vaccine among pregnant women. METHODS: Pregnant women were randomized to either receive or not receive weekly text messages. Women were told the messages would be about health-related behavior in pregnancy. Those randomized to the intervention group received two messages weekly for four consecutive weeks reinforcing that the influenza vaccine is recommended for all pregnant women and safe during pregnancy and breastfeeding...
February 1, 2017: Vaccine
https://www.readbyqxmd.com/read/28039625/the-influence-of-maternal-exposure-history-to-virus-and-medicine-during-pregnancy-on-congenital-heart-defects-of-fetus
#18
Qianhong Liang, Wei Gong, Dongming Zheng, Risheng Zhong, Yunjie Wen, Xiaodan Wang
Congenital heart disease (CHD) is the most common birth defect. It is due to dysfunction of the heart and great vessels during embryo development stage, or the channel was not closed after birth. This study focuses on investigating the influence of virus infection and medicine history during pregnancy on the incidence rate of CHD of fetus. We conducted a retrospective birth cohort study of infant born in the maternal and child health hospital of Fanyu district in Guangzhou. Five thousand three hundred eighty one cases with complete medical records, including mothers, fathers, and infants, were enrolled...
December 30, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28024955/pregnancy-as-a-risk-factor-for-severe-outcomes-from-influenza-virus-infection-a-systematic-review-and-meta-analysis-of-observational-studies
#19
REVIEW
Dominik Mertz, Johanna Geraci, Judi Winkup, Bradford D Gessner, Justin R Ortiz, Mark Loeb
BACKGROUND: Pregnancy is considered to be an important risk factor for severe complications following influenza virus infection. As a consequence, WHO recommendations prioritize pregnant women over other risk groups for influenza vaccination. However, the risk associated with pregnancy has not been systematically quantified. PURPOSE: Systematic review and meta-analysis of observational studies that reported on pregnancy as a risk factor for severe outcomes from influenza virus infection...
January 23, 2017: Vaccine
https://www.readbyqxmd.com/read/27988883/surveillance-of-adverse-events-after-seasonal-influenza-vaccination-in-pregnant-women-and-their-infants-in-the-vaccine-adverse-event-reporting-system-july-2010-may-2016
#20
Pedro Moro, Jane Baumblatt, Paige Lewis, Janet Cragan, Naomi Tepper, Maria Cano
INTRODUCTION: Routine immunization of pregnant women with seasonal inactivated influenza vaccines (IIVs) is recommended in all trimesters of pregnancy. A review of the Vaccine Adverse Event Reporting System (VAERS) during 1990-2009 did not find any unexpected patterns of pregnancy complications or fetal outcomes after administration of IIV or live attenuated influenza vaccines (LAIVs). During the 2009-2010 pandemic influenza A (H1N1) vaccination campaign, a study noted that the number of VAERS reports from pregnant women who received the H1N1 2009 inactivated monovalent vaccine (n = 288) increased compared with 1990-2009 seasonal IIV pregnancy reports (n = 148)...
February 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
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