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Maternal influenza

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https://www.readbyqxmd.com/read/27893896/association-between-influenza-infection-and-vaccination-during-pregnancy-and-risk-of-autism-spectrum-disorder
#1
Ousseny Zerbo, Yinge Qian, Cathleen Yoshida, Bruce H Fireman, Nicola P Klein, Lisa A Croen
Importance: Maternal infections and fever during pregnancy are associated with increased risk for autism spectrum disorders (ASDs). To our knowledge, no study has investigated the association between influenza vaccination during pregnancy and ASD. Objective: To investigate the association between influenza infection and vaccination during pregnancy and ASD risk. Design, Setting, and Participants: This cohort study included 196 929 children born at Kaiser Permanente Northern California from January 1, 2000 to December 31, 2010, at a gestational age of at least 24 weeks...
November 28, 2016: JAMA Pediatrics
https://www.readbyqxmd.com/read/27892877/detection-of-porcine-reproductive-and-respiratory-syndrome-virus-prrsv-and-influenza-a-virus-iav-in-oral-fluid-of-pigs
#2
Kinga Biernacka, Paweł Karbowiak, Paweł Wróbel, Tomasz Charęza, Michał Czopowicz, Gyula Balka, Christa Goodell, Rolf Rauh, Tomasz Stadejek
Recently oral fluid has become a novel sample type for pathogen nucleic acid and antibody detection, as it is easy to obtain with non-invasive procedures. The objective of the study was to analyze porcine reproductive and respiratory syndrome virus (PRRSV) and influenza A virus (IAV) circulation in growing pigs from three Polish production farms, using Real Time PCR and ELISA testing of oral fluid and serum. Oral fluids were collected every 2weeks, in the same 3-4 pens of pigs aged between 5 and 17weeks. Additionally, blood samples were collected every 4weeks from 4 pigs corresponding to the same pens as oral fluid and tested for the presence of PRRSV nucleic acid (pooled by 4) and antibodies...
September 21, 2016: Research in Veterinary Science
https://www.readbyqxmd.com/read/27888742/serological-evidence-for-high-prevalence-of-influenza-d-viruses-in-cattle-nebraska-united-states-2003-2004
#3
Junrong Luo, Lucas Ferguson, David R Smith, Amelia R Woolums, William B Epperson, Xiu-Feng Wan
Influenza D virus (IDV), a new member of the influenza virus family, was first reported in 2011 in swine in Oklahoma, USA, and then soon found in cattle across North America and Eurasia. Earlier studies suggested cattle serve as natural reservoir for IDV. The goal of this study is to perform a retrospective study looking at sera collected from Nebraska beef herds in 2003-2004 and 2014 for evidence of IDV antibodies. Results showed that all 40 randomly selected farms (2003-2004) we tested contained IDV seropositive adult animals and that approximately 98% of newborn calves (2014) had high levels of maternal antibodies against IDV...
November 23, 2016: Virology
https://www.readbyqxmd.com/read/27856770/update-from-the-advisory-committee-on-immunization-practices
#4
Jennifer E Schuster, Sean O'Leary, David W Kimberlin
The Advisory Committee on Immunization Practices (ACIP) consists of medical and public health experts who develop recommendations on vaccine use in the United States. The ACIP meets 3 times per year, and members and Centers for Disease Control (CDC) staff present findings and discuss vaccine research, vaccine effectiveness (VE) and safety, clinical trial results, and labeling/package insert information. Outbreaks of vaccine-preventable diseases and vaccine shortages are also discussed. Nonvoting representatives from the American Academy of Pediatrics and the Pediatric Infectious Diseases Society are present...
December 2016: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/27856157/the-serological-evidence-for-maternal-influenza-as-risk-factor-for-psychosis-in-offspring-is-insufficient-critical-review-and-meta-analysis
#5
REVIEW
Jean-Paul Selten, Fabian Termorshuizen
Maternal influenza during pregnancy has been suggested to increase the psychosis risk for the offspring. This hypothesis has been tested using "ecological" studies, which examined the risk for individuals born after epidemics, and "serological" studies, based on serological evidence. A study of the latter type obtained an increased schizophrenia risk for individuals exposed during the first trimester. A second study found a relationship between influenza at any time during gestation and risk for bipolar disorder with psychotic features...
November 14, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27784657/maternal-influenza-immunization-and-adverse-birth-outcomes-using-data-and-practice-to-inform-theory-and-research-design
#6
REVIEW
Varun K Phadke, Mark C Steinhoff, Saad B Omer, Noni E MacDonald
Maternal influenza immunization can reduce influenza-attributable morbidity and mortality among pregnant women and infants who are too young to be vaccinated. Data from empirical studies also support the hypothesis that immunization can protect the fetus against adverse outcomes if the mother is exposed to influenza. In their theoretical analysis in the Journal, Hutcheon et al. (Am J Epidemiol 2016;184(3):227-232) critiqued the existing evidence of the fetal benefits of maternal influenza immunization by calculating the sample sizes needed to demonstrate hypothetical reductions in risk and concluded that the benefits observed in empirical studies are likely implausible...
October 26, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27784656/hutcheon-et-al-respond-to-maternal-influenza-immunization-and-birth-outcomes
#7
Jennifer A Hutcheon, Deshayne B Fell, Michael L Jackson, Michael S Kramer, Justin R Ortiz, David A Savitz, Robert W Platt
No abstract text is available yet for this article.
October 26, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27773474/knowledge-attitudes-and-practices-of-healthcare-providers-in-the-country-of-georgia-regarding-influenza-vaccinations-for-pregnant-women
#8
Mariam Dvalishvili, Darejan Mesxishvili, Maia Butsashvili, George Kamkamidze, Deborah McFarland, Robert A Bednarczyk
OBJECTIVE: To document knowledge, attitudes, and practices of Georgian obstetrician-gynecologists concerning influenza infection and vaccination during pregnancy. METHODS: We conducted a cross-sectional study of obstetrician-gynecologists in 8 cities in the country of Georgian, from June to July, 2015, using an anonymous, self-administered, written survey. Collected data included demographics; knowledge, attitudes, and practices related to influenza vaccination during pregnancy; perceptions of influenza infection in pregnancy; perceived barriers to influenza vaccination during pregnancy; and willingness to receive education about influenza infection and vaccination during pregnancy...
October 20, 2016: Vaccine
https://www.readbyqxmd.com/read/27759021/protection-against-maternal-infection-associated-fetal-growth-restriction-proof-of-concept-with-a-microbial-derived-immunomodulator
#9
N M Scott, J F Lauzon-Joset, A C Jones, K T Mincham, N M Troy, J Leffler, M Serralha, S L Prescott, S A Robertson, C Pasquali, A Bosco, P G Holt, D H Strickland
Infection-associated inflammatory stress during pregnancy is the most common cause of fetal growth restriction and/or miscarriage. Treatment strategies for protection of at-risk mothers are limited to a narrow range of vaccines, which do not cover the bulk of the common pathogens most frequently encountered. Using mouse models, we demonstrate that oral treatment during pregnancy with a microbial-derived immunomodulator (OM85), currently used clinically for attenuation of infection-associated airway inflammatory symptoms in infants-adults, markedly reduces risk for fetal loss/growth restriction resulting from maternal challenge with bacterial lipopolysaccharide or influenza...
October 19, 2016: Mucosal Immunology
https://www.readbyqxmd.com/read/27742214/maternal-pertussis-and-influenza-immunization-coverage-and-attitude-of-health-care-workers-towards-these-recommendations-in-flanders-belgium
#10
Kirsten Maertens, Tessa Braeckman, Geert Top, Pierre Van Damme, Elke Leuridan
In Belgium, pertussis vaccination is recommended for all pregnant women in every pregnancy. Adults in close contact with young infants are equally advised to receive a pertussis containing booster dose. Maternal influenza vaccination is likewise recommended in Belgium in the second or third trimester of pregnancy, within the influenza season. A quantitative multicenter survey study has been performed between October 2014 and May 2015 in both postpartum women (N=823, response rate=89.2%) and health care workers (HCWs) (N=261) to assess the coverage of both vaccines during pregnancy along with the coverage of the pertussis cocoon strategy, and to evaluate the knowledge and recommending attitude of HCWs towards the maternal vaccination strategies and the cocoon strategy among surveyed women and HCWs...
October 11, 2016: Vaccine
https://www.readbyqxmd.com/read/27737646/maternal-vitamin-d-supplementation-during-pregnancy-and-lactation-to-prevent-acute-respiratory-infections-in-infancy-in-dhaka-bangladesh-mdari-trial-protocol-for-a-prospective-cohort-study-nested-within-a-randomized-controlled-trial
#11
Shaun K Morris, Lisa G Pell, Mohammed Ziaur Rahman, Michelle C Dimitris, Abdullah Mahmud, M Munirul Islam, Tahmeed Ahmed, Eleanor Pullenayegum, Tahmid Kashem, Shaila S Shanta, Jonathan Gubbay, Eszter Papp, Michelle Science, Stanley Zlotkin, Daniel E Roth
BACKGROUND: Early infancy is a high-risk period for severe acute respiratory infection (ARI), particularly in low-income countries with resource-limited health systems. Lower respiratory tract infection (LRTI) is commonly preceded by upper respiratory infection (URTI), and often caused by respiratory syncytial virus (RSV), influenza and other common community-acquired viral pathogens. Vitamin D status is a candidate modifiable early-life determinant of the host antiviral immune response and thus may influence the risk of ARI-associated morbidity in high-risk populations...
October 13, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27716730/survival-of-hiv-1-vertically-infected-children
#12
Mary-Ann Davies, Diana Gibb, Anna Turkova
PURPOSE OF REVIEW: It is 20 years since the start of the combination antiretroviral therapy (cART) era and more than 10 years since cART scale-up began in resource-limited settings. We examined survival of vertically HIV-infected infants and children in the cART era. RECENT FINDINGS: Good survival has been achieved on cART in all settings with up to 10-fold mortality reductions compared with before cART availability. Although mortality risk remains high in the first few months after cART initiation in young children with severe disease, it drops rapidly thereafter even for those who started with advanced disease, and longer term mortality risk is low...
September 2016: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/27667330/brief-education-to-promote-maternal-influenza-vaccine-uptake-a-randomized-controlled-trial
#13
Valerie Wing Yu Wong, Daniel Yee Tak Fong, Kris Yuet Wan Lok, Janet Yuen Ha Wong, Chu Sing, Alice Yin-Yin Choi, Carol Yuet Sheung Yuen, Marie Tarrant
BACKGROUND: Although pregnant women are the highest priority group for seasonal influenza vaccination, maternal influenza vaccination rates remain suboptimal. The purpose of this study was to evaluate the effect of a brief education intervention on maternal influenza vaccine uptake. METHODS: During the 2013-14 and 2014-15 influenza seasons, we recruited 321 pregnant women from the antenatal clinics of 4 out of 8 public hospitals in Hong Kong with obstetric services...
October 17, 2016: Vaccine
https://www.readbyqxmd.com/read/27663129/maternal-immunisation-ethical-issues
#14
Marcel Verweij, Philipp Lambach, Justin R Ortiz, Andreas Reis
There has been increased interest in the potential of maternal immunisation to protect maternal, fetal, and infant health. Maternal tetanus vaccination is part of routine antenatal care and immunisation campaigns in many countries, and it has played an important part in the reduction of maternal and neonatal tetanus. Additional vaccines that have been recommended for routine maternal immunisation include those for influenza and pertussis, and other vaccines are being developed. Maternal immunisation is controversial since regulators, professionals, and the public are often reluctant to accept pharmaceutical interventions during pregnancy...
September 20, 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27662592/maternally-derived-immunity-extends-swine-influenza-a-virus-persistence-within-farrow-to-finish-pig-farms-insights-from-a-stochastic-event-driven-metapopulation-model
#15
Charlie Cador, Nicolas Rose, Lander Willem, Mathieu Andraud
Swine Influenza A Viruses (swIAVs) have been shown to persist in farrow-to-finish pig herds with repeated outbreaks in successive batches, increasing the risk for respiratory disorders in affected animals and being a threat for public health. Although the general routes of swIAV transmission (i.e. direct contact and exposure to aerosols) were clearly identified, the transmission process between batches is still not fully understood. Maternally derived antibodies (MDAs) were stressed as a possible factor favoring within-herd swIAV persistence...
2016: PloS One
https://www.readbyqxmd.com/read/27603545/the-effects-of-influenza-vaccination-during-pregnancy-on-birth-outcomes-a-systematic-review-and-meta-analysis
#16
Marta C Nunes, Anushka R Aqil, Saad B Omer, Shabir A Madhi
Objective Numerous observational studies have evaluated the relationship between influenza vaccination during pregnancy and birth outcomes. The number of studies on this subject has increased, especially after the 2009 A/H1N1 pandemic (A/H1N1pdm09). This meta-analysis aims to determine the impact of maternal vaccination with either seasonal trivalent inactivated influenza vaccines (IIV) or A/H1N1pdm09 monovalent vaccines on the rates of preterm (PTB), small for gestational age (SGA), and low birth weight (LBW) births...
September 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27554107/maternal-morbidity-and-mortality-from-severe-sepsis-a-national-cohort-study
#17
Colleen D Acosta, David A Harrison, Kathy Rowan, D Nuala Lucas, Jennifer J Kurinczuk, Marian Knight
OBJECTIVES: To describe the incidence, characteristics and risk factors for critical care admission with severe maternal sepsis in the UK. DESIGN: National cohort study. SETTING: 198 critical care units in the UK. PARTICIPANTS: 646 pregnant and recently pregnant women who had severe sepsis within the first 24 hours of admission in 2008-2010. PRIMARY AND SECONDARY OUTCOME MEASURES: Septic shock, mortality...
2016: BMJ Open
https://www.readbyqxmd.com/read/27552608/limited-infant-protection-from-maternal-influenza-immunization
#18
Anita Slomski
No abstract text is available yet for this article.
August 23, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27541370/the-safety-of-maternal-immunization
#19
Annette K Regan
Maternal vaccination offers the opportunity to protect pregnant women and their infants against potentially serious disease. As both pregnant women and their newborns are vulnerable to severe illness, the potential public health impact of mass maternal vaccination programs is remarkable. Several high-income countries recommend seasonal influenza and acellular pertussis vaccines, and many developing countries recommend immunization against tetanus during pregnancy. There is a significant amount of literature supporting the safety of vaccination during pregnancy...
August 19, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27530456/maternally-derived-antibodies-do-not-prevent-transmission-of-swine-influenza-a-virus-between-pigs
#20
Charlie Cador, Séverine Hervé, Mathieu Andraud, Stéphane Gorin, Frédéric Paboeuf, Nicolas Barbier, Stéphane Quéguiner, Céline Deblanc, Gaëlle Simon, Nicolas Rose
A transmission experiment involving 5-week-old specific-pathogen-free (SPF) piglets, with (MDA(+)) or without maternally-derived antibodies (MDA(-)), was carried out to evaluate the impact of passive immunity on the transmission of a swine influenza A virus (swIAV). In each group (MDA(+)/MDA(-)), 2 seeders were placed with 4 piglets in direct contact and 5 in indirect contact (3 replicates per group). Serological kinetics (ELISA) and individual viral shedding (RT-PCR) were monitored for 28 days after infection...
2016: Veterinary Research
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