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Maruyama gastric

A Kawajiri, D Maruyama, A M Maeshima, J Nomoto, S Makita, H Kitahara, K-I Miyamoto, S Fukuhara, T Suzuki, W Munakata, K Tajima, J Itami, H Taniguchi, Y Kobayashi, K Tobinai
No abstract text is available yet for this article.
2016: Blood Cancer Journal
Tomoyuki Nakajima, Takeshi Uehara, Yasuhiro Maruyama, Mai Iwaya, Yukihiro Kobayashi, Hiroyoshi Ota
Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) is a putative intestinal stem cell marker that is also expressed in various tumors. To analyze its pathological characteristics in mucosal gastric signet-ring cell carcinoma (SRCC), we investigated Lgr5 expression in 35 intramucosal gastric SRCC patients using RNAscope, a newly developed RNA in situ hybridization technique. Lgr5 expression in individual tumor cells was scored semi-quantitatively from 0 to 400. Ki67 was also examined by immunohistochemistry, with a linear arrangement of Ki67-expressing cells present in 20 of 35 cases...
September 2016: Pathology International
Takeshi Nagai, Kazumitsu Ueda, Hiroyuki Hakoda, Shinya Okata, Shoko Nakata, Tetsuro Taira, Shigeo Aoki, Hideyuki Mishima, Akihiro Sako, Tsunehiko Maruyama, Minoru Okumura
BACKGROUND: Recently, gastrointestinal stromal tumors that have developed outside of the digestive tract have been reported. These tumors are collectively termed extra-gastrointestinal stromal tumors. Extra-gastrointestinal stromal tumors can also develop in the liver. Only eight case reports involving primary GIST of the liver have been published. We report a case and review the literature regarding this disease. CASE PRESENTATION: A 70-year-old woman with a past history of gastric cancer visited our hospital for regular inspection...
December 2016: Surgical Case Reports
Soichiro Kiyono, Hitoshi Maruyama, Takayuki Kondo, Tadashi Sekimoto, Taro Shimada, Masanori Takahashi, Osamu Yokosuka
No abstract text is available yet for this article.
August 17, 2016: Journal of Gastroenterology
Tetsuro Maruyama, Yuji Sugamoto, Daisuke Miyagishima, Toru Fukunaga, Kentaro Tasaki, Nobuyoshi Takeshita, Tomohide Tamachi, Yo Asai, Takashi Hosokawa, Eiichiro Ninomiya, Masayuki Kimura
Schwannomas are tumors and commonly occur in the head and neck region; however, they rarely present in the retroperitoneum. A 79-year-old man was admitted to our hospital for a follow-up of a tumor in the hepatic hilus. A 2.8 × 2.5 cm solid tumor located between the hepatic hilus and common hepatic artery was originally identified, and the size of the tumor had increased from 2.0 × 2.0 cm to 2.8 × 2.5 cm over the course of 3 years. The patient underwent percutaneous sonopsy, and the tumor was subsequently diagnosed as a benign schwannoma...
December 2015: Surgical Case Reports
Kazufumi Kobayashi, Hitoshi Maruyama, Soichiro Kiyono, Tadashi Sekimoto, Takayuki Kondo, Taro Shimada, Masanori Takahashi, Hidehiro Okugawa, Osamu Yokosuka
AIM: To determine the prognostic effect of portal hemodynamic responses after balloon-occluded retrograde transvenous obliteration (B-RTO) for gastric varices (GV) in cirrhosis patients. METHODS: This retrospective study consisted of 37 cirrhosis patients (62.5 ± 9.7 years) with medium- or large-grade GV treated with B-RTO. Portal hemodynamic response was assessed by the changes in flow volume in the portal trunk (PFV, mL/min) before and after the treatment; Group I showed increased PFV and Group II showed no increase in PFV...
March 2, 2016: Hepatology Research: the Official Journal of the Japan Society of Hepatology
Dezső Tóth, János Plósz, Miklós Török
Approximately thirty percent of patients with gastric cancer undergo an avoidable lymph node dissection with a higher rate of postoperative complication. Comparing the D1 and D2 dissections, it was found that there is a significant difference in morbidity, favoured D1 dissection without any difference in overall survival. Subgroup analysis of patients with T3 tumor shows a survival difference favoring D2 lymphadenectomy, and there is a better gastric cancer-related death and non-statistically significant improvement of survival for node-positive disease in patients with D2 dissection...
February 15, 2016: World Journal of Gastrointestinal Oncology
Soichiro Kiyono, Hitoshi Maruyama, Takayuki Kondo, Tadashi Sekimoto, Taro Shimada, Masanori Takahashi, Osamu Yokosuka
BACKGROUND: To examine the hemodynamic effect of the left gastric artery (LGA) on the esophageal varices (EV) in cirrhosis. METHODS: This was a prospective study performed in 48 cirrhosis patients (35 men, 13 women; median age 61.6 ± 11.3 years, range 38-83 years) with EV (medium 35, large 13), who underwent selective LGA angiography, hepatic venous catheterization, endoscopic ultrasonography (EUS) and Doppler ultrasonography before endoscopic treatment for EV...
September 2016: Journal of Gastroenterology
Takayuki Kondo, Hitoshi Maruyama, Soichiro Kiyono, Tadashi Sekimoto, Taro Shimada, Masanori Takahashi, Hidehiro Okugawa, Osamu Yokosuka, Hiroshi Kawahira, Tadashi Yamaguchi
BACKGROUND AND AIM: To demonstrate the effect of endoscopic injection sclerotherapy (EIS) with argon plasma coagulation (APC) as a primary/secondary prophylaxis for esophageal varies (EV) on portal hemodynamics and long-term outcomes in cirrhosis. METHODS: This prospective study included 48 cirrhotic patients (64.5 ± 11.4 years; 26 bleeders, 22 non-bleeders). Post-treatment outcomes (EIS and APC; median observation period, 12.8 months for recurrence and 21...
March 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Tadashi Sekimoto, Hitoshi Maruyama, Kazufumi Kobayashi, Soichiro Kiyono, Takayuki Kondo, Taro Shimada, Masanori Takahashi, Osamu Yokosuka
AIM: To evaluate the clinical features and prognoses in adult patients with extrahepatic portal vein obstruction (EHO) from the aspect of portal hypertension during the last 20 years in Japan. METHODS: There were 40 EHO patients (aged 21-77 years; mean ± standard deviation [SD], 54.6 ± 15.0). Clinical findings and prognoses were examined retrospectively during the median observation period of 71.6 months. RESULTS: Twenty-two patients (55%) showed positive signs of portal hypertension; 18 with esophageal varices (F0, one; F1, eight; F2, nine), two with gastric varices (F1, one; F2, one) and seven with mild ascites...
May 2016: Hepatology Research: the Official Journal of the Japan Society of Hepatology
Takayuki Kondo, Hitoshi Maruyama, Tadashi Sekimoto, Taro Shimada, Masanori Takahashi, Osamu Yokosuka
AIM: To elucidate the natural history and the longitudinal outcomes in cirrhotic patients with non-forward portal flow (NFPF). METHODS: The present retrospective study consisted of 222 cirrhotic patients (120 males and 102 females; age, 61.7 ± 11.1 years). The portal hemodynamics were evaluated at baseline and during the observation period using both pulsed and color Doppler ultrasonography. The diameter (mm), flow direction, mean flow velocity (cm/s), and mean flow volume (mL/min) were assessed at the portal trunk, the splenic vein, the superior mesenteric vein, and the collateral vessels...
August 7, 2015: World Journal of Gastroenterology: WJG
Hidehiro Kamezaki, Hitoshi Maruyama, Taro Shimada, Masanori Takahashi, Hidehiro Okugawa, Osamu Yokosuka
PURPOSE: To determine whether pretreatment portal flow direction can predict different clinical manifestations or prognosis after balloon-occluded retrograde transvenous obliteration (B-RTO) for gastric varices. METHODS: The subjects were 103 cirrhotic patients with medium- or large-grade gastric varices treated by B-RTO. Short- and long-term clinical outcomes were compared among patients with forward portal flow (F group) and those with reversed or to-and-fro portal flow (R group) on color Doppler sonography before B-RTO...
March 2013: Hepatology International
Shogo Tajima, Akihiko Ohata, Kenji Koda, Yasuhiko Maruyama
Intraductal papillary neoplasm of the bile duct (IPNB) exists in a pathway of multistep-carcinogenesis toward cholangiocarcinoma. Four subtypes are observed in IPNB, pancreatobiliary type, intestinal type, gastric type, and oncocytic type, similarly to the corresponding disease in the pancreas, intraductal papillary mucinous neoplasm (IPMN). IPNB can present with or without macroscopically visible mucin secretion. IPNB usually progresses to tubular adenocarcinoma. However, there are a limited number of well-described cases of gastric-type IPNB progressing not to tubular adenocarcinoma but to colloid carcinoma...
2015: International Journal of Clinical and Experimental Pathology
Masahiro Shinoda, Koichi Aiura, Yoshiyuki Yamagishi, Yohei Masugi, Kiminori Takano, Shotaro Maruyama, Tomoyuki Irino, Kaoru Takabayashi, Yoshinori Hoshino, Shin Nishiya, Taizo Hibi, Shigeyuki Kawachi, Minoru Tanabe, Masakazu Ueda, Michiie Sakamoto, Toshifumi Hibi, Yuko Kitagawa
Bouveret's syndrome, which is a gastric outlet obstruction caused by a gallstone in the duodenum, is a rare complication of gallstone disease. We report a case of Bouveret's syndrome in an 81-year-old woman who also exhibited incidental gallbladder cancer. She was admitted to our hospital complaining of upper abdominal pain and vomiting. A computed tomography examination showed a cholecystoduodenal fistula, a large impacted stone at the gastric outlet, and a dilated stomach. She was diagnosed as having Bouveret's syndrome...
October 2010: Clinical Journal of Gastroenterology
Hidehiro Kamezaki, Ryosaku Azemoto, Osamu Yokosuka, Tatsuya Fujimoto, Masamichi Obu, Masahiko Saito, Yu Yoshida, Yoshihiro Koma, Hitoshi Maruyama, Mototsugu Fujimori
Catheter ablation is a widely used treatment for atrial fibrillation. Gastric hypomotility due to periesophageal vagal plexus injury is a consequence of the extracardiac penetration of ablative energy. Some affected patients develop severe gastric dilatation requiring hospitalization. However, most previous reports have stated the cause of the subject's condition to be "unknown" or described the symptoms using obscure terms, such as "paralytic" or "gastroparesis." For example, one report stated that a few sites of severe gastric dilatation were secondary to "pyloric spasms;" however, no illustrations were provided in the paper...
2015: Internal Medicine
Shogo Tajima, Michihiko Waki, Akihiko Ohata, Kenji Koda, Yasuhiko Maruyama
Xanthogranulomatous gastritis (XGG) is a rarely encountered condition, and its causative mechanism is still unclear. Given that some types of xanthogranulomatous inflammation (XGI) are associated with pathogens, infection should be considered as a possible cause of XGG. Herein, we report a case of an 86-year-old woman presenting with a large, bleeding lesion resembling a submucosal tumor. Distal gastrectomy was performed, and the surgically resected specimen revealed a mass measuring 6 × 4.5 × 3 cm and appearing yellowish on the cut surface...
2015: International Journal of Clinical and Experimental Pathology
Isamu Hoshino, Tetsuro Maruyama, Hiromichi Fujito, Yutaka Tamura, Akiko Suganami, Hideki Hayashi, Taro Toyota, Yasunori Akutsu, Kentaro Murakami, Yuka Isozaki, Naoki Akanuma, Nobuyoshi Takeshita, Takeshi Toyozumi, Aki Komatsu, Hisahiro Matsubara
BACKGROUND/AIM: Although conventional staging laparoscopy (SL) has improved the diagnostic accuracy of peritoneal dissemination, novel technology is needed to increase the sensitivity of SL. We herein describe a new imaging method employing near-infrared (NIR) fluorescence imaging using a liposomal synthesized indocyanine green (ICG) liposomal derivative, LP-ICG-C18. METHODS AND RESULTS: LP-ICG-C18 is a NIR-photoactivating probe in which an ICG fluorophore is covalently conjugated with a phospholipid moiety...
March 2015: Anticancer Research
Youichirou Nushijima, Katsutoshi Nakano, Keishi Sugimoto, Kazunori Nakaguchi, Kazuomi Kan, Hirohide Maruyama, Sadayuki Doi, Shu Okamura, Kohei Murata
Metastatic gastric cancer is uncommon, and metastasis of colorectal cancer to the stomach is extremely rare. We report a case of metastatic gastric cancer that originated from transverse colon cancer. A 52-year-old woman underwent a left hemicolectomy and D3 lymph node dissection based on a diagnosis of transverse colon cancer. The pathology results were as follows: mucinous adenocarcinoma, type 2, 6 × 11 cm, ss, ly1 v1, pm (-), dm (-), n1 (+), P0, H0, M0, Stage IIIa. The patient received XELOX as postoperative adjuvant therapy for 6 months...
November 2014: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Ryota Otsuka, Toshiyuki Natsume, Takashi Maruyama, Hajime Tanaka, Hiroshi Matsuzaki
BACKGROUND: Roux-en-Y reconstruction after distal gastrectomy can result in delayed gastric emptying, called Roux stasis syndrome (RSS). The cause of RSS has not been completely identified. This study retrospectively investigated the development of RSS. METHODS: Between April 2008 and March 2014, we performed 138 procedures with distal gastrectomy using Roux-en-Y reconstruction. The development of RSS was analyzed and examined for correlations with the length of the operation, amount of blood loss, and surgical procedure...
May 2015: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Hitoshi Maruyama, Takayuki Kondo, Soichiro Kiyono, Tadashi Sekimoto, Masanori Takahashi, Osamu Yokosuka
OBJECTIVE: To examine the clinical effect of splenorenal shunt (SRS) on the long-term outcomes in patients with cirrhosis. METHODS: The study consisted of 162 cirrhosis patients (male 85, female 77; 62.6 ± 11.7 years). The clinical findings and prognosis were examined with respect to portal hemodynamics including collateral vessel patterns, with or without the presence of SRS or short gastric vein (SGV). Median observation period was 30 months. RESULTS: The incidence was 18...
May 2015: Scandinavian Journal of Gastroenterology
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