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https://www.readbyqxmd.com/read/28818453/two-locus-clines-on-the-real-line-with-a-step-environment
#1
Reinhard Bürger
The shape of allele-frequency clines maintained by migration-selection balance depends not only on the properties of migration and selection, but also on the dominance relations among alleles and on linkage to other loci under selection. We investigate a two-locus model in which two diallelic, recombining loci are subject to selection caused by an abrupt environmental change. The habitat is one-dimensional and unbounded, selection at each locus is modeled by step functions such that in one region one allele at each locus is advantageous and in the other deleterious...
August 14, 2017: Theoretical Population Biology
https://www.readbyqxmd.com/read/28811195/epileptic-interictal-discharges-are-more-frequent-during-nrem-slow-wave-downstates
#2
Péter Przemyslaw Ujma, Péter Halász, Anna Kelemen, Dániel Fabó, Loránd Erőss
Epileptiform activity in various but not all epilepsy and recording types and cerebral areas is more frequent in NREM sleep, and especially during sleep periods with high-amplitude EEG slow waves. Slow waves synchronize high-frequency oscillations: physiological activity from the theta through the gamma band usually appears during scalp-positive upstates while epileptiform activity occurs at transitory phases and the scalp-negative downstate. It has been proposed that interictal discharges (IIDs) are facilitated by the high degree of neuronal firing synchrony during slow wave transitory and downstates...
August 12, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28800546/mr-based-respiratory-and-cardiac-motion-correction-for-pet-imaging
#3
Thomas Küstner, Martin Schwartz, Petros Martirosian, Sergios Gatidis, Ferdinand Seith, Christopher Gilliam, Thierry Blu, Hadi Fayad, Dimitris Visvikis, F Schick, B Yang, H Schmidt, N F Schwenzer
PURPOSE: To develop a motion correction for Positron-Emission-Tomography (PET) using simultaneously acquired magnetic-resonance (MR) images within 90 s. METHODS: A 90 s MR acquisition allows the generation of a cardiac and respiratory motion model of the body trunk. Thereafter, further diagnostic MR sequences can be recorded during the PET examination without any limitation. To provide full PET scan time coverage, a sensor fusion approach maps external motion signals (respiratory belt, ECG-derived respiration signal) to a complete surrogate signal on which the retrospective data binning is performed...
August 3, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28794520/iran-s-land-suitability-for-agriculture
#4
Mohsen B Mesgaran, Kaveh Madani, Hossein Hashemi, Pooya Azadi
Increasing population has posed insurmountable challenges to agriculture in the provision of future food security, particularly in the Middle East and North Africa (MENA) region where biophysical conditions are not well-suited for agriculture. Iran, as a major agricultural country in the MENA region, has long been in the quest for food self-sufficiency, however, the capability of its land and water resources to realize this goal is largely unknown. Using very high-resolution spatial data sets, we evaluated the capacity of Iran's land for sustainable crop production based on the soil properties, topography, and climate conditions...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28768512/theory-of-synergistic-effects-hill-type-response-surfaces-as-null-interaction-models-for-mixtures
#5
Michael Schindler
BACKGROUND: The classification of effects caused by mixtures of agents as synergistic, antagonistic or additive depends critically on the reference model of 'null interaction'. Two main approaches are currently in use, the Additive Dose (ADM) or concentration addition (CA) and the Multiplicative Survival (MSM) or independent action (IA) models. We compare several response surface models to a newly developed Hill response surface, obtained by solving a logistic partial differential equation (PDE)...
August 2, 2017: Theoretical Biology & Medical Modelling
https://www.readbyqxmd.com/read/28768317/hue-shifts-produced-by-temporal-asymmetries-in-chromatic-signals
#6
Andrew Stockman, G Bruce Henning, Peter West, Andrew T Rider, Hannah E Smithson, Caterina Ripamonti
Observers viewed M- or L-cone-isolating stimuli and compared slowly-on and slowly-off sawtooth waveforms of the same mean chromaticity and luminance. Between 6 and 13 Hz, the mean hue of slowly-on L-cone and slowly-off M-cone sawtooth flicker appeared redder, and the mean hue of slowly-off L-cone and slowly-on M-cone sawtooth stimuli appeared greener-despite all the waveforms' having the same mean, near-yellow-appearing chromaticity. We measured the effect of the modulation depth and the slope of the sawtooth on the mean hue shifts as a function of temporal frequency...
August 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28755594/characteristics-and-applications-of-ecological-soil-substrate-for-rocky-slope-vegetation-in-cold-and-high-altitude-areas
#7
Hua Xu, Tian-Bin Li, Jian-Nan Chen, Chia-Nan Liu, Xiong-Hua Zhou, Lei Xia
Ecological restoration of steep rocky slopes generated by road cutting is usually difficult especially, in the cold and high-altitude environment, which is unfavorable for the growth of vegetation. With the focus on slope vegetation, an ecological soil substrate, synthesized with polyacrylamide (PAM), carboxymethyl cellulose (CMC), and Fly ash (FA) as the main components, was developed for spray seeding on the rocky slopes in cold and high-altitude regions, to provide a favorable environment for vegetation growth...
July 26, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28726966/ab-initio-performance-predictions-of-single-layer-in-v-tunnel-field-effect-transistors
#8
Juan Lu, Zhi-Qiang Fan, Jian Gong, Xiang-Wei Jiang
The device performances of both n-type and p-type tunnel field-effect transistors (TFETs) made of single-layer InX (X = N, P, As, Sb) are theoretically evaluated through density functional theory (DFT) and ab initio simulations in this paper. It is found that a promising steep subthreshold swing (SS) of [less-than-or-eq] 60 mV dec(-1) can be obtained with gate length LG = 15.2 nm for all two-dimensional (2D) InX TFETs. In particular, an outstanding on-current of ∼1058 μA μm(-1) (or 880 μA μm(-1)) is estimated in a 2D p-type (or n-type) InSb device, which could barely satisfy the ITRS requirements for future high-performance (HP) applications...
July 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28696773/rail-height-effects-on-safety-performance-of-midwest-guardrail-system
#9
Mojdeh Asadollahi Pajouh, Ramen D Julin, Cody S Stolle, John D Reid, Ronald K Faller
OBJECTIVE: Guardrail heights play a crucial role in the way that errant vehicles interact with roadside barriers. Low rail heights increase the propensity of vehicle rollover and override, while excessively-tall rails promote underride. Further, rail mounting heights and post embedment depths may be altered by variations in roadside terrain. An increased guardrail height may be desirable to accommodate construction tolerances, soil erosion, frost heave, and future roadway overlays. This study aimed to investigate and identify a maximum safe installation height for the Midwest Guardrail System, which would be robust and remain crashworthy before and after pavement overlays...
July 11, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28671281/water-status-and-must-composition-in-grapevine-cv-chardonnay-with-different-soils-and-topography-and-a-mini-meta-analysis-of-the-%C3%AE-13-c-water-potentials-correlation
#10
Luca Brillante, Olivier Mathieu, Jean Lévêque, Cornelis van Leeuwen, Benjamin Bois
BACKGROUND: The measurement of carbon isotopic discrimination in grape sugars at harvest (δ(13) C) is an integrated assessment of water status during ripening. It is an efficient alternative to assess variability in the field and discriminate between management zones in precision viticulture, but further work is needed to completely understand the signal. RESULTS: This work, spanning over three years, performed in a hillslope toposequence in Burgundy, delineates the relationships between main soil properties (gravel amount, slope, texture) and the grapevine water status assessed by δ(13) C...
July 3, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28668292/a-longitudinal-study-of-diurnal-cortisol-patterns-and-associated-factors-in-breast-cancer-patients-from-the-transition-stage-of-the-end-of-active-cancer-treatment-to-post-treatment-survivorship
#11
Fei-Hsiu Hsiao, Guey-Mei Jow, Wen-Hung Kuo, Ming-Yang Wang, King-Jen Chang, Yu-Ming Lai, Yu-Ting Chen, Chiun-Sheng Huang
OBJECTIVES: The aim of this study was to examine the changes in diurnal cortisol patterns and its associated factors among breast cancer patients over a 14-month follow up period. MATERIALS AND METHODS: A total of 85 breast cancer patients were recruited to participate in this study. Assessments were performed at baseline (T0), T1 (the 2nd month), T2 (the 5th month), T3 (the 8th month), and T4 (the 14th month). Salivary cortisol was measured and the following questionnaires were administered: BDI-II depression scale, European Organization for Research and Treatment of Cancer Core Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and its breast cancer-specific complementary measure (EORTC QLQ-BR23)...
June 28, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28667791/a-matter-of-perception-perceived-socio-economic-status-and-cortisol-on-the-island-of-utila-honduras
#12
Angela R García, Michael Gurven, Aaron D Blackwell
OBJECTIVES: Numerous studies link low objective and subjective socioeconomic status (SES) to chronic activation of the hypothalamic pituitary adrenal (HPA) axis. Here, we examine associations between objective and subjective SES and diurnal salivary cortisol, a primary HPA component, as well as demographic and ecological predictors associated with SES perceptions and changes in diurnal cortisol. METHODS: Participants were residents (age 18-79, n = 61) of Utila, a Honduran island where economic disparities are overt and geographically contained...
July 1, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28667194/the-role-of-environmental-factors-for-the-onset-of-restricted-mobility-outside-the-home-among-older-adults-with-osteoarthritis-a-prospective-cohort-study
#13
Merja Rantakokko, Ross Wilkie
OBJECTIVES: The study examines how environmental factors contribute to the onset of restricted mobility outside the home among older adults with osteoarthritis. METHODS: This is a prospective cohort study of adults aged 50 years and older with osteoarthritis (n=1802). Logistic regression tested the association between the onset of restricted mobility outside the home and health, sociodemographic and perceived environmental barriers (hills and steep slopes, inaccessible public buildings, poor pavement condition, lack of access to public parks or sport facilities, heavy traffic or speeding cars and poor weather)...
June 30, 2017: BMJ Open
https://www.readbyqxmd.com/read/28647913/how-adaptation-makes-low-firing-rates-robust
#14
Arthur S Sherman, Joon Ha
Low frequency firing is modeled by Type 1 neurons with a SNIC, but, because of the vertical slope of the square-root-like f-I curve, low f only occurs over a narrow range of I. When an adaptive current is added, however, the f-I curve is linearized, and low f occurs robustly over a large I range. Ermentrout (Neural Comput. 10(7):1721-1729, 1998) showed that this feature of adaptation paradoxically arises from the SNIC that is responsible for the vertical slope. We show, using a simplified Hindmarsh-Rose neuron with negative feedback acting directly on the adaptation current, that whereas a SNIC contributes to linearization, in practice linearization over a large interval may require strong adaptation strength...
December 2017: Journal of Mathematical Neuroscience
https://www.readbyqxmd.com/read/28625526/body-mass-index-and-all-cause-mortality-in-chronic-kidney-disease-a-dose-response-meta-analysis-of-observational-studies
#15
REVIEW
Mehran Rahimlu, Sakineh Shab-Bidar, Kurosh Djafarian
This article provides a dose-response meta-analysis to evaluate the relationship between body mass index (BMI) and all-cause and disease-specific mortality in chronic kidney disease (CKD) by pooling together early stage, hemodialysis, and peritoneal dialysis patients. We evaluated eligible studies that published between 1966 and December 2014 by searching in PubMed, Object View and Interaction Design (OVID), and the Scopus databases. We used random-effects generalized least squares spline models for trend estimation to derive pooled dose-response estimates...
July 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/28617337/tunable-temperature-response-of-a-thermochromic-photonic-gel-sensor-containing-n-isopropylacrylamide-and-4-acryloyilmorpholine
#16
Hwanam Kye, Young Gook Koh, Youkyung Kim, Sung Gu Han, Hyunjung Lee, Wonmok Lee
In this study, thermochromic photonic gels were fabricated using 2-hydroxyethyl methacrylate (HEMA) as a hydrogel building block, and 4-Acryloyl morpholine (ACMO) and N-isopropylacrylamide (NIPAAM) as thermoresponsive monomers with different critical solution temperature behaviors. Rapid photopolymerization of opal-templated monomer mixtures of varying ACMO contents formed five individual thermochromic inverse opal photonic gels integrated on a single substrate. With temperature variation from 10 °C to 80 °C, the changes in reflective colors and reflectance spectra of the respective thermochromic gels were noted, and λpeak changes were plotted...
June 15, 2017: Sensors
https://www.readbyqxmd.com/read/28616175/seasonal-habitat-use-by-elephants-loxodonta-africana-in-the-mole-national-park-of-ghana
#17
George Ashiagbor, Emmanuel Danquah
To avoid unnecessary waste of limited resources and to help prioritize areas for conservation efforts, this study aimed to provide information on habitat use by elephants between the wet and dry seasons in the Mole National Park (MNP) of Ghana. We compiled coordinates of 516 locations of elephants' encounters, 256 for dry season and 260 for wet season. Using nine predictor variables, we modeled the probability of elephant's distribution in MNP. We threshold the models to "suitable" and "nonsuitable" regions of habitat use using the equal training sensitivity and specificity values of 0...
June 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28613894/individual-defects-in-inas-ingaassb-gasb-nanowire-tunnel-field-effect-transistors-operating-below-60-mv-decade
#18
Elvedin Memisevic, Markus Hellenbrand, Erik Lind, Axel R Persson, Saurabh Sant, Andreas Schenk, Johannes Svensson, Lars-Erik Wernersson, Lars Reine Wallenberg
Tunneling Field-Effect Transistors (TunnelFET), a leading steep-slope transistor candidate, is still plagued by defect response and there is a large discrepancy between measured and simulated device performance. In this work, highly scaled InAs-InxGa1-xAsySb1-y-GaSb vertical nanowire TunnelFET with ability to operate well below 60 mV/decade at technically relevant currents are fabricated and characterized. The structure, composition, and strain is characterized using transmission electron microscopy with emphasis on the heterojunction...
June 14, 2017: Nano Letters
https://www.readbyqxmd.com/read/28567175/carrier-properties-of-b-atomic-layer-doped-si-films-grown-by-ecr-ar-plasma-enhanced-cvd-without-substrate-heating
#19
Masao Sakuraba, Katsutoshi Sugawara, Takayuki Nosaka, Hisanao Akima, Shigeo Sato
The atomic-layer (AL) doping technique in epitaxy has attracted attention as a low-resistive ultrathin semiconductor film as well as a two-dimensional (2-D) carrier transport system. In this paper, we report carrier properties for B AL-doped Si films with suppressed thermal diffusion. B AL-doped Si films were formed on Si(100) by B AL formation followed by Si cap layer deposition in low-energy Ar plasma-enhanced chemical-vapor deposition without substrate heating. After fabrication of Hall-effect devices with the B AL-doped Si films on unstrained and 0...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28545891/numerical-modelling-of-methane-oxidation-efficiency-and-coupled-water-gas-heat-reactive-transfer-in-a-sloping-landfill-cover
#20
S Feng, C W W Ng, A K Leung, H W Liu
Microbial aerobic methane oxidation in unsaturated landfill cover involves coupled water, gas and heat reactive transfer. The coupled process is complex and its influence on methane oxidation efficiency is not clear, especially in steep covers where spatial variations of water, gas and heat are significant. In this study, two-dimensional finite element numerical simulations were carried out to evaluate the performance of unsaturated sloping cover. The numerical model was calibrated using a set of flume model test data, and was then subsequently used for parametric study...
May 22, 2017: Waste Management
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