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https://www.readbyqxmd.com/read/28092318/opening-injection-pressure-is-higher-in-intraneural-compared-with-perineural-injections-during-simulated-nerve-blocks-of-the-lower-limb-in-fresh-human-cadavers
#1
Kris Vermeylen, Marlies Hermans, Filiep Soetens, Evie Vereecke, Thorsten Steinfeldt, Gerbrand Groen, Admir Hadzic, Marc Van de Velde
BACKGROUND AND OBJECTIVES: Needle-induced nerve trauma and intraneural injection can lead to neurologic injury during peripheral nerve blocks. In this study, we assessed the utility of opening injection pressure (OIP), time to OIP, and rate of rise to OIP in detecting needle-nerve contact and intraneural injection. METHODS: Five common ultrasound-guided blocks of the femoral, saphenous, subgluteal sciatic, tibial, and common peroneal nerves were simulated in 10 fresh cadavers...
January 13, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28091741/chemical-physical-and-biological-factors-shape-littoral-invertebrate-community-structure-in-coal-mining-end-pit-lakes
#2
Andreas Luek, Joseph B Rasmussen
Aquatic invertebrates form the base of the consumer food web in lakes. In coal-mining end-pit lakes, invertebrates are exposed to an environment with potentially challenging physical and chemical features. We hypothesized that the physical and chemical features of end-pit lakes reduce critical littoral habitat and thus reduce invertebrate diversity, thereby limiting the potential for these lakes to be naturalized. We used a multivariate approach using principle component analysis and redundancy analysis to study relationships between invertebrate community structure, habitat features, and water quality in five end-pit lakes and five natural lakes in the Rocky Mountain foothills of west-central Alberta, Canada...
January 13, 2017: Environmental Management
https://www.readbyqxmd.com/read/28081432/changes-in-age-patterns-of-suicide-in-australia-the-united-states-japan-and-hong-kong
#3
John Snowdon, Julie Phillips, Baoliang Zhong, Takashi Yamauchi, Helen F K Chiu, Yeates Conwell
The patterns of association between age and suicide rate vary by country, subpopulation and gender, and over time. To shed light on factors associated with these differences, we analysed suicide data from four populations, two 'Western' (Australia, the United States [US]) and two Asian (Japan and Hong Kong). We computed suicide rates in five-year age-groups (between 10 and 14 years and 85+ years) for men and women separately, and present graphical representations of the age patterns during selected five-year periods...
January 4, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28080302/the-road-to-bribery-and-corruption
#4
Nils C Köbis, Jan-Willem van Prooijen, Francesca Righetti, Paul A M Van Lange
Major forms of corruption constitute a strong threat to the functioning of societies. The most frequent explanation of how severe corruption emerges is the slippery-slope metaphor-the notion that corruption occurs gradually. While having widespread theoretical and intuitive appeal, this notion has barely been tested empirically. We used a recently developed paradigm to test whether severely corrupt acts happen gradually or abruptly. The results of four experimental studies revealed a higher likelihood of severe corruption when participants were directly given the opportunity to engage in it (abrupt) compared with when they had previously engaged in minor forms of corruption (gradual)...
January 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28080038/tracking-catalyst-redox-states-and-reaction-dynamics-in-ni-fe-oxyhydroxide-oxygen-evolution-reaction-oer-electrocatalysts-the-role-of-catalyst-support-and-electrolyte-ph
#5
Mikaela Goerlin, Jorge Ferreira de Araújo, Henrike Schmies, Denis Bernsmeier, Soeren Dresp, Manuel Gliech, Zenonas Jusys, Petko Chernev, Ralph Kraehnert, Holger Dau, Peter Strasser
Ni-Fe oxyhydroxides are the most active known electrocatalysts for the oxygen evolution reaction (OER) in alkaline electrolytes and are therefore of great scientific and technological importance in the context of electrochemical energy conversion. Here we uncover, investigate, and discuss previously unaddressed effects of conductive supports and the electrolyte pH on the Ni-Fe oxide catalyst redox behavior and catalytic OER activity, combining operando UV-vis spectro-electrochemistry, operando electrochemical mass spectrometry (DEMS), and in-situ cryo X-ray absorption spectroscopy (XAS)...
January 12, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28054936/silicon-and-germanium-nanowire-electronics-physics-of-conventional-and-unconventional-transistors
#6
Walter M Weber, Thomas Mikolajick
Research in the field of electronics of one-dimensional group-IV semiconductor structures has attracted increasing attention over the past 15 years. The exceptional combination of the unique one-dimensional electronic transport properties with the mature material know-how of highly integrated silicon and germanium technology holds the promise of enhancing state-of-the-art electronics. In addition of providing conduction channels that can bring conventional field effect transistors to the uttermost scaling limits, the physics of 1-D group IV nanowires endows new device principles...
January 5, 2017: Reports on Progress in Physics
https://www.readbyqxmd.com/read/28046994/su-f-t-607-study-of-dose-falloff-slope-in-rapidarc-planning-of-lung-sbrt
#7
D Desai, G Narayanasamy, S Senthamizhchelvan, H Elasmar, R Zwicker, E Johnson
PURPOSE: SBRT of lung tumor results in steep dose fall-off outside the PTV to limit the normal tissue dose. RTOG report 0915 recommended metrics for plan quality measure, CI, D2cm, R50% and HDloc were evaluated. This study was aimed at ascertaining moderate to low dose spillage using 5 mm ring structures outside the PTV. METHODS: In this retrospective study, 41 clinical RapidArc lung SBRT plans (Eclipse TPS ver 8.9) previously treated at our institution in a TrueBeam STx linac were analyzed...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28013090/walking-duration-and-slope-steepness-determine-the-effect-of-downslope-walking-on-the-soleus-h-reflex-pathway
#8
Elizabeth Arnold, Ben Farmer, Melissa Keightley, Dustin Lee, Taylor Rigel, Maruf Hoque, Manning J Sabatier
The purpose of this study was to determine if the effect of downslope walking (DSW) on spinal excitability depends on walking duration and slope steepness, and if findings from the soleus (Sol) generalize to the tibialis anterior (TA). Sol and TA Hmax and Mmax were measured before and after four DSW doses (time/slope, min/%) on separate days (10/-15, 20/-15, 10/-25, 20/-25, n=14), and one 20-min bout of level walking (LW, n=12), always at 2.5 mph. Heart rate (HR) and ratings of perceived exertion (RPE) were measured during walking...
December 21, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/28000516/speech-perception-in-children-with-cochlear-implants-for-continua-varying-in-formant-transition-duration
#9
Kathryn Guillot Blankenship, Ralph N Ohde, Jong Ho Won, Mark Hedrick
PURPOSE: To examine the developmental course of labial and alveolar manner of articulation contrasts, and to determine how that course may be different for typically developing (TD) children with cochlear implants (CI). METHOD: Eight young adults, eight TD 5-8 year-old children, and seven 5-8 year-old children with CIs participated. Labial /ba/-/wa/ and alveolar /da/-/ja/ continua stimuli were presented, with each continuum consisting of nine synthetic stimuli varying in F2 and F3 transition duration...
December 21, 2016: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/27941915/fully-transparent-flexible-tin-doped-zinc-oxide-thin-film-transistors-fabricated-on-plastic-substrate
#10
Dedong Han, Yi Zhang, Yingying Cong, Wen Yu, Xing Zhang, Yi Wang
In this work, we have successfully fabricated bottom gate fully transparent tin-doped zinc oxide thin film transistors (TZO TFTs) fabricated on flexible plastic substrate at low temperature by RF magnetron sputtering. The effect of O2/Ar gas flow ratio during channel deposition on the electrical properties of TZO TFTs was investigated, and we found that the O2/Ar gas flow ratio have a great influence on the electrical properties. TZO TFTs on flexible substrate has very nice electrical characteristics with a low off-state current (Ioff) of 3 pA, a high on/off current ratio of 2 × 10(7), a high saturation mobility (μsat) of 66...
December 12, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27939172/stable-bipedal-walking-with-a-swing-leg-protraction-strategy
#11
Pranav A Bhounsule, Ali Zamani
In bipedal locomotion, swing-leg protraction and retraction refer to the forward and backward motion, respectively, of the swing-leg before touchdown. Past studies have shown that swing-leg retraction strategy can lead to stable walking. We show that swing-leg protraction can also lead to stable walking. We use a simple 2D model of passive dynamic walking but with the addition of an actuator between the legs. We use the actuator to do full correction of the disturbance in a single step (a one-step dead-beat control)...
January 25, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/27914377/evaluating-multipulse-integration-as-a-neural-health-correlate-in-human-cochlear-implant-users-relationship-to-spatial-selectivity
#12
Ning Zhou, Bryan E Pfingst
The decrease of psychophysical detection thresholds as a function of pulse rate for a fixed-duration electrical pulse train is referred to as multipulse integration (MPI). The MPI slopes correlate with anatomical and physiological indices of cochlear health in guinea pigs with cochlear implants. The aim of the current study was to assess whether the MPI slopes were related to the spatial spread of activation by electrical stimulation. The hypothesis was that MPI is dependent on the total number of excitable neurons at the stimulation site, with broader neural excitation producing a steeper threshold decrease as a function of stimulation rate...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27902491/the-adaptation-rate-of-a-quantitative-trait-in-an-environmental-gradient
#13
R Hermsen
The spatial range of a species habitat is generally determined by the ability of the species to cope with biotic and abiotic variables that vary in space. Therefore, the species range is itself an evolvable property. Indeed, environmental gradients permit a mode of evolution in which range expansion and adaptation go hand in hand. This process can contribute to rapid evolution of drug resistant bacteria and viruses, because drug concentrations in humans and livestock treated with antibiotics are far from uniform...
November 30, 2016: Physical Biology
https://www.readbyqxmd.com/read/27890416/larix-decidua-%C3%AE-18-o-tree-ring-cellulose-mainly-reflects-the-isotopic-signature-of-winter-snow-in-a-high-altitude-glacial-valley-of-the-european-alps
#14
Giovanni Leonelli, Giovanna Battipaglia, Paolo Cherubini, Matthias Saurer, Rolf T W Siegwolf, Maurizio Maugeri, Barbara Stenni, Stella Fusco, Valter Maggi, Manuela Pelfini
We analyzed the chronologies of cellulose stable isotopes (δ(13)C and δ(18)O) and tree-ring widths from European larch (Larix decidua) in a high-altitude site (2190ma.s.l.) at the bottom of a glacial valley in the Italian Alps, and investigated their dependence on monthly meteorological variables and δ(18)O precipitation values. The δ(18)O of tree-ring cellulose appears to be strongly driven by the δ(18)O of winter snowfall (November to March), which suggests that larch trees mostly use the snow-melt water of the previous winter during the growing season...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27888424/export-of-non-point-source-suspended-sediment-nitrogen-and-phosphorus-from-sloping-highland-agricultural-fields-in-the-east-asian-monsoon-region
#15
Arif Reza, Jaesung Eum, Sungmin Jung, Youngsoon Choi, Jeffrey S Owen, Bomchul Kim
Excess sediment and nutrient export from agricultural fields with steep slopes is a major concern linked to surface water quality in Korea. In this study, the export of suspended sediment (SS), total nitrogen (TN), and total phosphorus (TP) and their event mean concentrations (EMCs) in surface runoff from a highland mixed land use (61% forested, 30% cropped, 9% other) watershed were quantified. In 2007, the Korean Ministry of Environment (MoE) declared the study area as a priority region for non-point source (NPS) pollution management and initiated various best management practices (BMPs) in the study watershed...
December 2016: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27882352/quantitative-evaluation-of-the-antiretroviral-efficacy-of-dolutegravir
#16
Sarah B Laskey, Robert F Siliciano
The second-generation HIV-1 integrase strand transfer inhibitor (InSTI) dolutegravir (DTG) has had a major impact on the treatment of HIV-1 infection. Here we describe important but previously undetermined pharmacodynamic parameters for DTG. We show that the dose-response curve slope, which indicates cooperativity and is a major determinant of antiviral activity, is higher for DTG than for first-generation InSTIs. This steepness does not reflect inhibition of multiple steps in the HIV-1 life cycle, as is the case for allosteric integrase inhibitors and HIV-1 protease inhibitors...
November 17, 2016: JCI Insight
https://www.readbyqxmd.com/read/27878409/analysis-of-the-functional-muscle-bone-unit-of-the-forearm-in-patients-with-phenylketonuria-by-peripheral-quantitative-computed-tomography
#17
Daniela Choukair, Carolin Kneppo, Reinhard Feneberg, Eckhard Schönau, Martin Lindner, Stefan Kölker, Georg F Hoffmann, Burkhard Tönshoff
Bone disease in patients with phenylketonuria (PKU) is incompletely characterized. We therefore analyzed, in a cross-sectional study radius macroscopic bone architecture and forearm muscle size by peripheral quantitative computed tomography (pQCT) and muscle strength by hand dynamometry in a large cohort (n = 56) of adolescent and adult patients with PKU aged 26.0 ± 8.9 (range, 11.8-41.5) years. Data were compared with a reference population (n = 700) from the DONALD study using identical methodology...
November 22, 2016: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/27866743/a-data-mining-framework-for-exploring-the-multi-relation-between-fish-species-and-water-quality-through-self-organizing-map
#18
Wen-Ping Tsai, Shih-Pin Huang, Su-Ting Cheng, Kwang-Tsao Shao, Fi-John Chang
The steep slopes of rivers can easily lead to large variations in river water quality during typhoon seasons in Taiwan, which may poses significant impacts on riverine eco-hydrological environments. This study aims to investigate the relationship between fish communities and water quality by using artificial neural networks (ANNs) for comprehending the upstream eco-hydrological system in northern Taiwan. We collected a total of 276 heterogeneous datasets with 8 water quality parameters and 25 fish species from 10 sampling sites...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27830350/longitudinal-changes-in-audiometric-phenotypes-of-age-related-hearing-loss
#19
Kenneth I Vaden, Lois J Matthews, Mark A Eckert, Judy R Dubno
Presbyacusis, or age-related hearing loss, can be characterized in humans as metabolic and sensory phenotypes, based on patterns of audiometric thresholds that were established in animal models. The metabolic phenotype is thought to result from deterioration of the cochlear lateral wall and reduced endocochlear potential that decreases cochlear amplification and produces a mild, flat hearing loss at lower frequencies coupled with a gradually sloping hearing loss at higher frequencies. The sensory phenotype, resulting from environmental exposures such as excessive noise or ototoxic drugs, involves damage to sensory and non-sensory cells and loss of the cochlear amplifier, which produces a 50-70 dB threshold shift at higher frequencies...
November 9, 2016: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/27816820/the-impact-of-perceived-intensity-and-frequency-of-police-work-occupational-stressors-on-the-cortisol-awakening-response-car-findings-from-the-bcops-study
#20
John M Violanti, Desta Fekedulegn, Michael E Andrew, Tara A Hartley, Luenda E Charles, Diane B Miller, Cecil M Burchfiel
Police officers encounter unpredictable, evolving, and escalating stressful demands in their work. Utilizing the Spielberger Police Stress Survey (60-item instrument for assessing specific conditions or events considered to be stressors in police work), the present study examined the association of the top five highly rated and bottom five least rated work stressors among police officers with their awakening cortisol pattern. Participants were police officers enrolled in the Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) study (n=338)...
January 2017: Psychoneuroendocrinology
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