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https://www.readbyqxmd.com/read/28422528/effect-of-psychopharmacotherapy-on-body-mass-index-among-children-and-adolescents-with-bipolar-disorders
#1
Ayush Patel, Wenyaw Chan, Rajender R Aparasu, Melissa Ochoa-Perez, Jeff T Sherer, Rohan Medhekar, Hua Chen
OBJECTIVE: To assess the long-term effect of all treatment options for pediatric bipolar disorders on body mass index (BMI) and to explore individual characteristics associated with less BMI increase during psychotropic medication exposures. METHODS: A retrospective cohort study was conducted by using the 1995 to 2010 General Electric Electronic Medical Record database. Individuals aged 18 years or younger who had a new bipolar disorder episode were identified. Treatment exposure was defined based on the medication regimens patients received, which include atypical antipsychotic (AT) monotherapy, mood stabilizer (MS) monotherapy, antidepressant (AD) monotherapy, AT+MS polytherapy, AT+AD polytherapy, MS+AD polytherapy, and no treatment...
April 19, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28402791/survey-of-corticioid-fungi-in-north-american-pinaceous-forests-reveals-hyperdiversity-underpopulated-sequence-databases-and-species-that-are-potentially-ectomycorrhizal
#2
Lisa M Rosenthal, Karl-Henrik Larsson, Sara Branco, Judy A Chung, Sydney I Glassman, Hui-Ling Liao, Kabir G Peay, Dylan P Smith, Jennifer M Talbot, John W Taylor, Else C Vellinga, Rytas Vilgalys, Thomas D Bruns
The corticioid fungi are commonly encountered, highly diverse, ecologically important, and understudied. We collected specimens in 60 pine and spruce forests across North America to survey corticioid fungal frequency and distribution and to compile an internal transcribed spacer (ITS) database for the group. Sanger sequences from the ITS region of vouchered specimens were compared with sequences on GenBank and UNITE, and with high-throughput sequence data from soil and roots taken at the same sites. Out of 425 high-quality Sanger sequences from vouchered specimens, we recovered 223 distinct operational taxonomic units (OTUs), the majority of which could not be assigned to species by matching to the BLAST database...
2017: Mycologia
https://www.readbyqxmd.com/read/28388853/psychometrically-equivalent-bisyllabic-words-for-speech-recognition-threshold-testing-in-vietnamese
#3
Richard W Harris, David L McPherson, Claire M Hanson, Dennis L Eggett
OBJECTIVE: This study identified, digitally recorded, edited and evaluated 89 bisyllabic Vietnamese words with the goal of identifying homogeneous words that could be used to measure the speech recognition threshold (SRT) in native talkers of Vietnamese. DESIGN: Native male and female talker productions of 89 Vietnamese bisyllabic words were recorded, edited and then presented at intensities ranging from -10 to 20 dBHL. Logistic regression was used to identify the best words for measuring the SRT...
April 7, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28386922/technical-descriptions-of-four-hemispherectomy-approaches-from-the-pediatric-epilepsy-surgery-meeting-at-gothenburg-2014
#4
James E Baumgartner, Jeffrey P Blount, Thomas Blauwblomme, P Sarat Chandra
Hemispherectomy is a complex multistep procedure with a steep learning curve. Several surgical approaches have been developed, but each requires considerable practice to master. Four experienced pediatric neurosurgeons, who participated in the 2014 Gothenburg Pediatric Epilepsy Surgery Meeting, provided succinct technical summaries of four hemispherectomy approaches: modified functional hemispherectomy, peri-insular hemispherotomy, parasagittal hemispherotomy, and endoscopic-assisted hemispherotomy. No clinical or outcome data are included...
April 2017: Epilepsia
https://www.readbyqxmd.com/read/28371805/restitution-slope-is-principally-determined-by-steady-state-action-potential-duration
#5
Michael J Shattock, Kyung Chan Park, Hsiang-Yu Yang, Angela Wc Lee, Steve Niederer, Kenneth T MacLeod, James Winter
AimsThe steepness of the action potential duration (APD) restitution curve and local tissue refractoriness are both thought to play important roles in arrhythmogenesis. Despite this, there has been little recognition of the apparent association between steady-state APD and the slope of the restitution curve. The objective of this study was to test the hypothesis that restitution slope is determined by APD and to examine the relationship between restitution slope, refractoriness and susceptibility to VF.Methods and ResultsExperiments were conducted in isolated hearts and ventricular myocytes from adult guinea pigs and rabbits...
March 23, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28349665/steeper-change-in-body-mass-across-four-decades-predicts-poorer-cardiometabolic-outcomes-at-midlife
#6
Hong Xian, Terrie Vasilopoulos, Weijian Liu, Richard L Hauger, Kristen C Jacobson, Michael J Lyons, Matthew Panizzon, Chandra A Reynolds, Eero Vuoksimaa, William S Kremen, Carol E Franz
OBJECTIVE: This study examined patterns of change in adiposity across four decades starting in young adulthood as well as associations between change and midlife cardiometabolic outcomes. METHODS: BMI was assessed at ages 20, 40, 56, and 62 years in 977 male veterans from the Vietnam Era Twin Study of Aging. Age 62 (range 56-66) cardiometabolic outcomes included hypertension, diabetes, dyslipidemia, inflammation, and ischemic heart disease. Analyses included latent growth modeling (LGM), latent class growth modeling (LCGM), and logistic regression models...
April 2017: Obesity
https://www.readbyqxmd.com/read/28344912/the-topography-of-a-continental-indenter-the-interplay-between-crustal-deformation-erosion-and-base-level-changes-in-the-eastern-southern-alps
#7
J Robl, B Heberer, G Prasicek, F Neubauer, S Hergarten
The topography of the eastern Southern Alps (ESA) reflects indenter tectonics causing crustal shortening, surface uplift, and erosional response. Fluvial drainages were perturbed by Pleistocene glaciations that locally excavated alpine valleys. The Late Miocene desiccation of the Mediterranean Sea and the uplift of the northern Molasse Basin led to significant base level changes in the far field of the ESA and the Eastern Alps (EA), respectively. Among this multitude of mechanisms, the processes that dominate the current topographic evolution of the ESA and the ESA-EA drainage divide have not been identified...
January 2017: Journal of Geophysical Research. Earth Surface
https://www.readbyqxmd.com/read/28336970/a-steep-slope-transistor-combining-phase-change-and-band-to-band-tunneling-to-achieve-a-sub-unity-body-factor
#8
Wolfgang A Vitale, Emanuele A Casu, Arnab Biswas, Teodor Rosca, Cem Alper, Anna Krammer, Gia V Luong, Qing-T Zhao, Siegfried Mantl, Andreas Schüler, A M Ionescu
Steep-slope transistors allow to scale down the supply voltage and the energy per computed bit of information as compared to conventional field-effect transistors (FETs), due to their sub-60 mV/decade subthreshold swing at room temperature. Currently pursued approaches to achieve such a subthermionic subthreshold swing consist in alternative carrier injection mechanisms, like quantum mechanical band-to-band tunneling (BTBT) in Tunnel FETs or abrupt phase-change in metal-insulator transition (MIT) devices...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28331933/conformation-of-the-proximal-tibia-and-cranial-cruciate-ligament-disease-in-small-breed-dogs
#9
Jan Janovec, Michal Kyllar, Duncan Midgley, Martin Owen
OBJECTIVES: To investigate the conformation of the proximal tibia in small breed dogs with and without cranial cruciate ligament disease (CCLD) and to identify morphologic abnormalities that may predispose to development of CCLD. METHODS: Mediolateral radiographs of the entire tibia of dogs <15 kg with surgically confirmed CCLD were retrospectively evaluated. Proximal tibial width (PTW), tibial plateau length (TPL), tibial plateau angle as described by Slocum and Slocum (sTPA), proximal tibial tuberosity angle (PTTA), tibial plateau angle as described by Inauen and colleagues (nTPA), and diaphyseal tibial width (DTW) were measured...
March 23, 2017: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/28318454/infant-stranger-fear-trajectories-predict-anxious-behaviors-and-diurnal-cortisol-rhythm-during-childhood
#10
Carol A Van Hulle, Mollie N Moore, Kathryn Lemery-Chalfant, H Hill Goldsmith, Rebecca J Brooker
Although a robust literature has linked stable, high levels of fear across childhood to increased risk for anxiety problems, less is known about alternative pathways to anxiety. We tested two putatively normative developmental pathways of early fearfulness for their distinct associations with behavioral (anxiety-related behaviors and symptoms) and biological (diurnal cortisol) markers of anxiety risk in middle childhood in a community-based sample (n = 107). Steeper increases in fear from 6 to 36 months predicted more parent-reported anxiety symptoms at age 8 years...
March 20, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28306291/new-paradigm-for-turbulent-transport-across-a-steep-gradient-in-toroidal-plasmas
#11
H S Xie, Y Xiao, Z Lin
First principles gyrokinetic simulation of the edge turbulent transport in toroidal plasmas finds a reverse trend in the turbulent transport coefficients under strong gradients. It is found that there exist both linear and nonlinear critical gradients for the nonmonotonicity of transport characteristics. The discontinuity of the transport flux slope around the turning gradient shows features of a second order phase transition. Under a strong gradient the most unstable modes are in nonground eigenstates with unconventional mode structures, which significantly reduces the effective correlation length and thus reverse the transport trend...
March 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28303142/nitrogen-use-efficiency-of-coffee-at-the-vegetative-stage-as-influenced-by-fertilizer-application-method
#12
Alveiro Salamanca-Jimenez, Timothy A Doane, William R Horwath
Nitrogen (N) is the most limiting nutrient for coffee production in Colombia. An adequate supply is especially important during the vegetative period of growth, since any deficiency during this short period is known to have lasting effects on subsequent coffee bean production. Urea fertilizer is commonly applied on the soil surface since steep slopes hamper incorporation into soil, a practice which increases the risk of N volatilization. Little information is available on N recovery during early growth stages under different fertilizer application practices...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28295107/self-wrapping-of-an-ouzo-drop-induced-by-evaporation-on-a-superamphiphobic-surface
#13
Huanshu Tan, Christian Diddens, Michel Versluis, Hans-Jürgen Butt, Detlef Lohse, Xuehua Zhang
Evaporation of multi-component drops is crucial to various technologies and has numerous potential applications because of its ubiquity in nature. Superamphiphobic surfaces, which are both superhydrophobic and superoleophobic, can give a low wettability not only for water drops but also for oil drops. In this paper, we experimentally, numerically and theoretically investigate the evaporation process of millimetric sessile ouzo drops (a transparent mixture of water, ethanol, and trans-anethole) with low wettability on a superamphiphobic surface...
April 12, 2017: Soft Matter
https://www.readbyqxmd.com/read/28260600/trends-in-population-blood-pressure-and-determinant-factors-for-population-blood-pressure
#14
Ulla Overgaard Andersen
Strategies to reduce the burden of blood pressure attributable diseases require knowledge of secular trend in PBP and its determinants. The issues were investigated in the Copenhagen City Heart Study. The design of CCHS is a repeated measures study. Such designs are uniquely suited to studying changes of an outcome and what risk factors may be associated with that outcome. Repeated measures studies are very well suited for trend analysis by using mixed effect analyses. SBP decreased about 2 mmHg in 25 years...
March 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28255568/association-between-lateral-posterior-tibial-slope-body-mass-index-and-acl-injury-risk
#15
Katherine M Bojicic, Mélanie L Beaulieu, Daniel Y Imaizumi Krieger, James A Ashton-Miller, Edward M Wojtys
BACKGROUND: While body mass index (BMI), a modifiable parameter, and knee morphology, a nonmodifiable parameter, have been identified as risk factors for anterior cruciate ligament (ACL) rupture, the interaction between them remains unknown. An understanding of this interaction is important because greater compressive axial force (perhaps due to greater BMI) applied to a knee that is already at an increased risk because of its geometry, such as a steep lateral posterior tibial slope, could further increase the probability of ACL injury...
February 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28248309/microstructures-define-melting-of-molybdenum-at-high-pressures
#16
Rostislav Hrubiak, Yue Meng, Guoyin Shen
High-pressure melting anchors the phase diagram of a material, revealing the effect of pressure on the breakdown of the ordering of atoms in the solid. An important case is molybdenum, which has long been speculated to undergo an exceptionally steep increase in melting temperature when compressed. On the other hand, previous experiments showed nearly constant melting temperature as a function of pressure, in large discrepancy with theoretical expectations. Here we report a high-slope melting curve in molybdenum by synchrotron X-ray diffraction analysis of crystalline microstructures, generated by heating and subsequently rapidly quenching samples in a laser-heated diamond anvil cell...
March 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/28222978/toxicity-of-platinum-palladium-and-rhodium-to-daphnia-magna-in-single-and-binary-metal-exposure-experiments
#17
Sonja Zimmermann, Carolina Wolff, Bernd Sures
Mainly due to automobile traffic, but also due to other sources, the platinum group elements (PGE) platinum (Pt), palladium (Pd) and rhodium (Rh) are introduced into aquatic biotopes where they accumulate in sediments of lakes and rivers. However, the toxicity of these noble metals to aquatic organisms is not well understood and especially toxicity studies under standardized condition are lacking. Thus, the toxicity of Pt, Pd and Rh to Daphnia magna was tested in single metal exposure experiments according to OECD guideline 202...
February 17, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28222134/gis-based-landform-classification-of-bronze-age-archaeological-sites-on-crete-island
#18
Athanasios V Argyriou, Richard M Teeuw, Apostolos Sarris
Various physical attributes of the Earth's surface are factors that influence local topography and indirectly influence human behaviour in terms of habitation locations. The determination of geomorphological setting plays an important role in archaeological landscape research. Several landform types can be distinguished by characteristic geomorphic attributes that portray the landscape surrounding a settlement and influence its ability to sustain a population. Geomorphometric landform information, derived from digital elevation models (DEMs), such as the ASTER Global DEM, can provide useful insights into the processes shaping landscapes...
2017: PloS One
https://www.readbyqxmd.com/read/28211180/slope-of-psychometric-functions-and-termination-rule-analysis-for-low-contrast-acuity-charts
#19
Andrew Carkeet, Ian L Bailey
PURPOSE: To assess whether the slopes of psychometric functions for measuring low contrast letter acuity were different from those for measuring high contrast letter acuity. METHODS: Ten participants, wearing their best spectacle correction, were assessed monocularly. Stimuli were logarithmic progression charts, generated on a computer monitor, with nine rows of five randomised Sloan letters generated in either high contrast format (Weber contrast 99.2%) or low contrast format (Weber contrast 18...
March 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28183867/propulsion-in-hexapod-locomotion-how-do-desert-ants-traverse-slopes
#20
Toni Wöhrl, Lars Reinhardt, Reinhard Blickhan
The employment of an alternating tripod gait to traverse uneven terrains is a common characteristic shared among many hexapoda. Since this could be one specific cause for their ecological success, we examined the alternating tripod gait of the desert ant Cataglyphis fortis together with their ground reaction forces and weight-specific leg impulses for level locomotion and on moderate (±30°) and steep (±60°) slopes in order to understand mechanical functions of individual legs during inclined locomotion...
February 9, 2017: Journal of Experimental Biology
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