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nocturnal enuresis

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https://www.readbyqxmd.com/read/28636262/increased-renal-concentrating-ability-after-long-term-oral-desmopressin-lyophilisate-treatment-contributes-to-continued-success-for-monosymptomatic-nocturnal-enuresis
#1
Hirokazu Ikeda, Tsuneki Watanabe, Keiichi Isoyama
OBJECTIVES: To investigate renal concentrating ability after long-term fast-melting oral desmopressin lyophilisate treatment in children with monosymptomatic nocturnal enuresis. METHODS: The present retrospective study involved 58 children (43 boys, 15 girls; aged 6-12 years) with nocturnal enuresis receiving oral desmopressin lyophilisate. After treatment for 4 weeks with a complete response, patients were placed on a reduced dose of 120 μg on alternate days. Moring urine osmolality was measured using urine samples obtained after medication and non-medication dry nights...
June 21, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28634090/evaluation-of-the-effect-of-3-month-bladder-basic-advice-in-children-with-monosymptomatic-nocturnal-enuresis
#2
Marcin Tkaczyk, Michał Maternik, Anna Krakowska, Agnieszka Wosiak, Monika Miklaszewska, Katarzyna Zachwieja, Dariusz Runowski, Anna Jander, Dariusz Ratajczak, Agata Korzeniecka-Kozyrska, Izabella Mader-Wołyńska, Katarzyna Kiliś-Pstrusińska
INTRODUCTION: Advice (BBA) into the standards of patients' care in both monosymptomatic and non-monosymptomatic nocturnal enuresis. Although the idea of this recommendation was clear and reflects clinical experience, duration and efficacy have not been definitely established. Recent data have demonstrated the lack of efficacy of BBA and a fierce discussion has ensued. The present study was aimed to assess the efficacy of BBA in a group of previously untreated children with primary monosymptomatic nocturnal enuresis (MNE)...
June 1, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28491176/nontraumatic-urinary-bladder-rupture-presenting-as-renal-pseudo-failure-and-ascites
#3
Andrew Mark, Moshe Meister, Benjamin Opara, Robert Chow
A 24-year-old man, with past medical history significant only for nocturnal enuresis until the age of 12 years, presented to the emergency department with acute abdominal pain after an episode of difficulty with micturition in the middle of the night. On presentation, physical examination was suggestive of ascites and laboratories revealed an elevated serum creatinine of 1.88 mg/dL. He was subsequently found to have a ruptured bladder, without any inciting trauma, which required surgical repair. His only surgical history is an unknown, apparently urologic, surgery when he was 11-12 years old...
June 2017: Radiology case reports
https://www.readbyqxmd.com/read/28457803/evaluation-of-urinary-aquaporin-2-and-plasma-copeptin-as-biomarkers-of-effectiveness-of-desmopressin-acetate-for-the-treatment-of-monosymptomatic-nocturnal-enuresis
#4
Taichi Hara, Yoshiyuki Ohtomo, Amane Endo, Shinichi Niijima, Masato Yasui, Toshiaki Shimizu
PURPOSE: Desmopressin is a synthetic V2-specific analog of antidiuretic hormone (arginine vasopressin), widely used as a first-line treatment for monosymptomatic nocturnal enuresis. However, no biomarkers to predict desmopressin effectiveness have yet been established. Because arginine vasopressin is unstable, we prospectively measured the major urine concentration factors aquaporin-2 and copeptin (as a surrogate marker for vasopressin) in patients with monosymptomatic nocturnal enuresis, and evaluated whether they are useful for predicting desmopressin treatment outcome...
April 27, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28450726/effect-of-drd4-receptor-616-c-g-polymorphism-on-brain-structure-and-functional-connectivity-density-in-pediatric-primary-nocturnal-enuresis-patients
#5
Bing Yu, Na Chang, Yao Lu, Hongwei Ma, Na Liu, Qiyong Guo
The dopamine D4 receptor (DRD4) promoter (-616; rs747302) has been associated with primary nocturnal enuresis (PNE); however, its relationship with neuroimaging has not been investigated. Therefore, we assessed the effects of the DRD4 -616 C/G single nucleotide polymorphism on the gray matter volume (GMV) and functional connectivity density (FCD) during resting-state functional magnetic resonance imaging in children with PNE using voxel-based morphometry and FCD methods. Genomic and imaging data were obtained from 97 children with PNE and 105 healthy controls...
April 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28444706/adolescents-with-nocturnal-enuresis-and-daytime-urinary-incontinence-how-can-pediatric-and-adult-care-be-improved-ici-rs-2015
#6
REVIEW
Alexander von Gontard, Linda Cardozo, Angie Rantell, Jens-Christian Djurhuus
AIMS: Nocturnal enuresis (NE) and daytime urinary incontinence (DUI) are common in adolescents. The aim of this paper was to review studies on prevalence, clinical symptoms and associated risk factors and to formulate recommendations for assessment and treatment. MATERIALS AND METHODS: A systematic Scopus search was performed and relevant publications were selected. The topic was discussed during the ICI-RS meeting in 2015. RESULTS: One to two percent of older adolescents are affected by NE and 1% by DUI...
April 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28439419/chronic-complications-and-quality-of-life-of-patients-living-with-sickle-cell-disease-and-receiving-care-in-three-hospitals-in-cameroon-a-cross-sectional-study
#7
Anne M Andong, Eveline D T Ngouadjeu, Cavin E Bekolo, Vincent S Verla, Daniel Nebongo, Yannick Mboue-Djieka, Simeon-Pierre Choukem
BACKGROUND: Sickle Cell Disease (SCD) is associated with chronic multisystem complications that significantly influence the quality of life (QOL) of patients early in their life. Although sub-Saharan Africa bears 75% of the global burden of SCD, there is a paucity of data on these complications and their effects on the QOL. We aimed to record these chronic complications, to estimate the QOL, and to identify the corresponding risk factors in patients with SCD receiving care in three hospitals in Cameroon...
2017: BMC Hematology
https://www.readbyqxmd.com/read/28415139/primary-nocturnal-enuresis-a-review-of-assessment-and-treatment-in-a-single-referral-centre3
#8
Salvatore Arena, Mario Patricolo
INTRODUCTION: Aim was to investigate the prevalence of primary monosymptomatic and non-monosymptomatic noctural enuresis (PMNE and PNMNE) and associated factors in a major referral centre for NE in Abu Dhabi. MATERIAL AND METHODS: Children referred to a Paediatric Continence Clinic, between 2014 and 2016, for PNE were included. Exclusion criteria were neuropathic bladder, abnormality of the bladder and bowel, urethral stenosis, children with neurological and psychiatric problems, patients that did not complete the diagnostic protocol, patients with follow-up less than six months...
April 17, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28386646/the-role-of-upper-airway-obstruction-and-snoring-in-the-etiology-of-monosymptomatic-nocturnal-enuresis-in-children
#9
Huseyin Bugra Karakas, Muhammet Recai Mazlumoglu, Eda Simsek
This study evaluated the necessity of examining the upper airway in children with nocturnal enuresis. 225 children (aged 5-16 years), who were referred from the urology outpatient clinic between May 2015 and May 2016 and who had completed toilet training, were included in this study. Participants were separated into monosymptomatic nocturnal enuresis (MNE) (group 1) and without MNE (group 2) groups. Tonsil hypertrophy, adenoid vegetation, septal deviation, turbinate hypertrophy, allergic rhinitis, upper airway obstruction, and snoring etiology were assessed...
April 6, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28381366/nocturnal-incontinence-in-children-with-fetal-alcohol-spectrum-disorders-fasd-in-a-south-african-cohort
#10
Sylvia Roozen, Leana Olivier, Justine Niemczyk, Alexander von Gontard, Gjalt-Jorn Y Peters, Gerjo Kok, Denis Viljoen, Leopold Curfs
INTRODUCTION: Fetal alcohol spectrum disorders (FASD) are one of the leading preventable causes of intellectual disabilities (ID). Not much is known about the topic of pediatric incontinence related to FASD, for example nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI). So far, incontinence problems have been examined among children with other specific syndromes. OBJECTIVE: The aim of the present study is to investigate the possible presence of incontinence among children with FASD in a South African cohort...
March 23, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28361164/clinics-in-diagnostic-imaging-175-corpus-callosum-glioblastoma-multiforme-gbm-butterfly-glioma
#11
Vijay Krishnan, Tze Chwan Lim, Francis Cho Hao Ho, Wilfred Cg Peh
A 54-year-old man presented with change in behaviour, nocturnal enuresis, abnormal limb movement and headache of one week's duration. The diagnosis of butterfly glioma (glioblastoma multiforme) was made based on imaging characteristics and was further confirmed by biopsy findings. As the corpus callosum is usually resistant to infiltration by tumours, a mass that involves and crosses the corpus callosum is suggestive of an aggressive neoplasm. Other neoplastic and non-neoplastic conditions that may involve the corpus callosum and mimic a butterfly glioma, as well as associated imaging features, are discussed...
March 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28279978/desmopressin-for-nocturia-in-adults
#12
(no author information available yet)
Desmopressin has been used for many years in the treatment of diabetes insipidus, nocturnal enuresis (involuntary urination while asleep) and nocturia associated with multiple sclerosis (in adults aged up to 65 years); it has also been recommended in certain circumstances for the treatment of nocturia in men and women (previously, an unlicensed use).(1,2) Recently, a new brand of desmopressin sublingual tablet (lyophilisate-an orally disintegrating tablet; Noqdirna-Ferring) has been licensed for use in adults of any age for the treatment of nocturia due to idiopathic nocturnal polyuria...
March 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28260347/adhd-and-enuresis-a-study-about-effectiveness-of-treatment-with-methylphenidate-or-desmopressin-in-a-pediatric-population
#13
Pietro Ferrara, Valeria Sannicandro, Francesca Ianniello, Enrica Quattrocchi, Annamaria Sbordone, Tommasangelo Petitti, Paolo Mariotti
BACKGROUND: To evaluate the effectiveness of treatment with methylphenidate or desmopressin (dDAVP) in patients with comorbid ADHD and enuresis. METHODS: We enrolled 103 patients affected by ADHD and 125 patients with monosymptomatic nocturnal enuresis (NE). Data were collected between January 2014 and December 2015. The study was carried out in compliance with the Helsinki Declaration. RESULTS: About children with ADHD, 9/103 (8,7%) were also suffering from NE; of those 8/9 followed treatment with methylphenidate and cognitive behavioral therapy...
March 3, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28247065/the-changes-of-urethral-morphology-recognized-in-voiding-cystourethrography-after-endoscopic-transurethral-incision-for-posterior-urethral-valve-in-boys-with-intractable-daytime-urinary-incontinence-and-nocturnal-enuresis
#14
Taiju Hyuga, Shigeru Nakamura, Shina Kawai, Taro Kubo, Rieko Furukawa, Toshinori Aihara, Makiko Mieno, Hideo Nakai
PURPOSE: Endoscopic transurethral incision (TUI) of posterior urethral valve (PUV) can improve daytime urinary incontinence (DUI) and nocturnal enuresis (NE). However, the underlying mechanism has not been elucidated. In this study, we retrospectively examined the mobility of the urethra before and after TUI by measuring the urethral angle with voiding cystourethrography (VCUG), to clarify the effects of TUI on the morphology of the urethra during voiding. METHODS: Between July 2010 and December 2014, 29 boys with intractable DUI and/or NE were diagnosed as PUV and underwent endoscopic TUI...
February 28, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28208214/pathogenesis-of-enuresis-towards-a-new-understanding
#15
REVIEW
Tryggve Nevéus
Enuresis was historically viewed as a primarily psychiatric disorder, but this understanding has changed dramatically since the end of the last century, when it became clear that somatic factors, such as nocturnal polyuria as a result of vasopressin deficiency, nocturnal detrusor overactivity and high arousal thresholds, all play a crucial role in enuresis pathogenesis. It has also become clear that enuresis is inherited in the majority of cases, although the correlation between genotype and enuretic phenotype is not straightforward...
March 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28199734/nocturnal-enuresis-impaired-children-s-quality-of-life-and-friendships
#16
Ingrid Jönson Ring, Tryggve Nevéus, Agneta Markström, Kristina Arnrup, Farhan Bazargani
AIM: There have not been any continence-specific measurement tools in Swedish that have allowed clinicians to investigate the quality of life (QoL) in children with bladder dysfunction. This study evaluated the QoL in Swedish children with nocturnal enuresis and tested the reliability of a Swedish translation of the Paediatric Incontinence Questionnaire (PinQ). METHODS: This prospective study comprised 46 children aged six to 18 years with nocturnal enuresis, who completed the PinQ after it was translated into Swedish...
February 15, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28197893/gender-differences-in-clinical-and-polysomnographic-features-of-obstructive-sleep-apnea-a-clinical-study-of-2827-patients
#17
Ozen K Basoglu, Mehmet Sezai Tasbakan
PURPOSE: Obstructive sleep apnea (OSA) is underdiagnosed in females due to different clinical presentation. We aimed to determine the effect of gender on clinical and polysomnographic features and identify predictors of OSA in women. METHODS: Differences in demographic, clinical, and polysomnographic parameters between 2052 male and 775 female OSA patients were compared. RESULTS: In female OSA patients, age (56.1 ± 9.7 vs. 50.4 ± 11...
February 14, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28195439/noninvasive-imaging-of-brain-oxygen-metabolism-in-children-with-primary-nocturnal-enuresis-during-natural-sleep
#18
Bing Yu, Mingzhu Huang, Xu Zhang, Hongwei Ma, Miao Peng, Qiyong Guo
A series of studies have revealed that nocturnal enuresis is closely related to hypoxia in children with primary nocturnal enuresis (PNE). However, brain oxygen metabolism of PNE children has not been investigated before. The purpose of this study was to investigate changes in whole-brain cerebral metabolic rate of oxygen (CMRO2 ), cerebral blood flow (CBF), and oxygen extraction fraction (OEF) in children suffering from PNE. We used the newly developed T2-relaxation-under-spin-tagging (TRUST) magnetic resonance imaging technique...
February 14, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28190701/parental-perception-and-factors-associated-with-treatment-strategies-for-primary-nocturnal-enuresis
#19
Thomson T Tai, Brent T Tai, Yu-Jun Chang, Kuo-Hsuan Huang
OBJECTIVE: The aim was to investigate the factors influencing parents seeking reasonable managements for their child and their overall outlook toward primary nocturnal enuresis (PNE). STUDY DESIGN: We recruited 93 children with PNE from enuresis clinics and requested their parents to complete questionnaires regarding their child's medical history and behavior, their methods for coping with PNE, and their perception of enuresis. Logistic regression models were applied to investigate factors influencing the parents to adopt a positive approach toward enuresis and to subsequently seek a medical consultation...
January 30, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28165541/obstructive-sleep-disordered-breathing-enuresis-and-combined-disorders-in-children-chance-or-related-association
#20
Marco Zaffanello, Giorgio Piacentini, Giuseppe Lippi, Vassilios Fanos, Emma Gasperi, Luana Nosetti
Nocturnal enuresis is usually diagnosed and treated by a primary paediatrician or family practitioner; if there is any doubt, the children may be referred to a paediatric urologist. Obstructive sleep-disordered breathing is a complex, multifactorial disorder. Adenotonsillar hypertrophy is considered an important factor associated with obstructive sleep apnoea syndrome. Enuresis and obstructive sleep-disordered breathing are both frequent problems of sleep in childhood. We conducted an electronic search in Medline, Scopus and the ISI Web of Science to look for published material and identify a putative link between nocturnal enuresis and obstructive sleep-disordered breathing...
February 6, 2017: Swiss Medical Weekly
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