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nocturnal enuresis

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https://www.readbyqxmd.com/read/29217876/nocturnal-enuresis-in-india-are-we-diagnosing-and-managing-correctly
#1
REVIEW
N M Reddy, H Malve, R Nerli, P Venkatesh, I Agarwal, V Rege
Nocturnal enuresis is a common problem affecting school-aged children worldwide. Although it has significant impact on child's psychology, it is always under-recognized in India and considered as a condition which will outgrow with advancing age. Nocturnal enuresis classified as primary or secondary and monosymptomatic or nonmonosymptomatic. Factors that cause enuresis include genetic factors, bladder dysfunction, psychological factors, and inappropriate antidiuretic hormone secretion, leading to nocturnal polyuria...
November 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/29198064/claiming-desmopressin-therapeutic-equivalence-in-children-requires-pediatric-data-a-population-pkpd-analysis
#2
Robin Michelet, Lien Dossche, Charlotte Van Herzeele, Jan Van Bocxlaer, An Vermeulen, Johan Vande Walle
PURPOSE: For a new formulation of a drug, only pharmacokinetic bioequivalence with the original formulation has to be demonstrated in healthy, young adults. However, "children are not small adults," and to guarantee a safe and effective treatment, age-adapted drug development is required. Desmopressin, a vasopressin analogue prescribed for nocturnal enuresis in children, was studied as an example formulation first developed in adults and then extrapolated to a pediatric indication. METHODS: Population pharmacokinetic and pharmacodynamic modeling was used to analyze previously published desmopressin data of 18 children suffering from nocturnal enuresis...
December 3, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29175540/the-effect-of-family-assistance-to-wake-children-with-monosymptomatic-enuresis-in-alarm-therapy-a-pilot-study
#3
Shoji Tsuji, Chikushi Suruda, Takahisa Kimata, Jiro Kino, Sohsaku Yamanouchi, Kazunari Kaneko
PURPOSE: Alarm therapy is widely used as first-line treatment for nocturnal enuresis (NE). However, some children do not wake when nocturnal urination activates the alarm. It is currently unclear whether waking the child when the alarm is activated improves the efficacy of alarm therapy. This study aimed to investigate the efficacy of alarm therapy for NE when children do not wake in response to the sound and their parents do not wake them. MATERIALS AND METHODS: Detailed information regarding incontinence was retrospectively obtained from 78 of 112 patients who underwent alarm therapy between 2006 and 2016 and completed a questionnaire and a 14-day bladder diary...
November 23, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29174376/evidence-of-reduced-bladder-capacity-during-nighttime-in-children-with-monosymptomatic-nocturnal-enuresis
#4
B Borg, K Kamperis, L H Olsen, S Rittig
INTRODUCTION: Bladder capacity in children with nocturnal enuresis is assessed by maximal voided volumes (MVV) obtained through daytime frequency volume (FV) charts. Although a degree of association has been demonstrated, daytime MVV does not consistently correspond with the nocturnal bladder capacity (NBC) in monosymptomatic nocturnal enuresis (MNE). It was hypothesized that isolated reduced NBC is a common phenomenon in children with nocturnal enuresis, despite normal daytime bladder function...
October 27, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29151300/the-effect-of-antidiuretic-hormone-on-urine-and-serum-electrolyte-levelsin-children-with-primary-monosymptomatic-nocturnal-enuresis
#5
(no author information available yet)
Background/aim: The data concerning the effects of desmopressin on water/electrolyte disturbances of children with primary monosymptomatic nocturnal enuresis (PMNE) are limited. In the present study we aimed to evaluate the effect and tolerability of desmopressin on blood and urine electrolytes and osmolality in PMNE.Materials and methods: Thirty-five children with PMNE between the ages of 5 and 15 participated in the study. Patients collected urine during the daytime and acknowledged the night time fluid restriction before starting to use the desmopressin tablets...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29123651/recent-advances-in-managing-and-understanding-enuresis
#6
REVIEW
Charlotte Van Herzeele, Johan Vande Walle, Karlien Dhondt, Kristian Vinter Juul
Enuresis, particularly in children during sleep, can be a debilitating condition, affecting the quality of life of the child and his or her family. The pathophysiology of nocturnal enuresis, though not clear, revolves around the inter-related mechanisms of overactive bladder, excessive nocturnal urine production, and sleep fragmentation. The first mechanism is more related to isolated nocturnal voiding, whereas the latter two are more related to nocturnal enuresis, in which circadian variations in arginine vasopressin hormone play a key role...
2017: F1000Research
https://www.readbyqxmd.com/read/29067072/behavioral-factors-for-predicting-severity-of-enuresis-and-treatment-responses-in-different-compliance-groups-receiving-behavioral-therapy
#7
Yanli Ma, Xiaomei Liu, Ying Shen
OBJECTIVE: To investigate behavioral factors for predicting severity of nocturnal enuresis and compare response rates in different compliance groups of behavioral interventions. METHODS: Three hundred eleven children diagnosed with nocturnal enuresis were enrolled. This study was conducted at Beijing Children's Hospital affiliated to the Capital Medical University from September 2016 to December 2016. Correlation of severity of enuresis and behavioral factors was investigated...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29060371/a-prospective-study-of-examining-physiological-signals-for-estimating-occurrence-of-nocturnal-enuresis
#8
Junhyung Moon, Sangyeop Lee, Taeho Lee, Saewon Kye, Yong Seung Lee, Seung-Chul Shin, Kyoungwoo Lee
The nocturnal enuresis is challenging due to the increased social activities of the children. This disorder significantly bothers both the children and their parents in psychological, behavioral, social, and financial manners. However, the primary treatments have limitations and further are not able to completely cure the disorder. In order to reduce pain and burdens of patients and their parents, it is important to accurately estimate when the enuretic incident occurs in advance. For the estimation, we have comprehensively investigated various studies of the nocturnal enuresis in the diverse fields...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29055129/desmopressin-for-treating-nocturia-in-men
#9
REVIEW
Julia Han, Jae Hung Jung, Caitlin J Bakker, Mark H Ebell, Philipp Dahm
BACKGROUND: Nocturia is the bothersome symptom of awakening one or more times per night to void. Desmopressin is a commonly used medication for treating nocturia. OBJECTIVES: To assess the effects of desmopressin as compared to other interventions in the treatment of nocturia in men. SEARCH METHODS: We performed a comprehensive search of medical literature with no restrictions on the language of publication or publication status. The date of the latest search of all databases was August 2017...
October 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29045258/early-behavioral-risks-of-childhood-and-adolescent-daytime-urinary-incontinence-and-nocturnal-enuresis
#10
Monica M A Vasconcelos, Patricia East, Estela Blanco, Emily S Lukacz, Gabriela Caballero, Betsy Lozoff, Sheila Gahagan
OBJECTIVE: To investigate whether infant temperament and childhood internalizing, externalizing, and inattention symptoms increase the likelihood of daytime urinary incontinence or nocturnal enuresis at 10 years and adolescence (11.9-17.8 years). METHOD: Data were from a longitudinal cohort of 1119 healthy Chilean children. We assessed behavioral symptoms at infancy, 5 years, and 10 years and their relationship with subsequent daytime urinary incontinence and nocturnal enuresis...
November 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29019014/incontinence-in-autism-spectrum-disorder-a-systematic-review
#11
REVIEW
Justine Niemczyk, C Wagner, A von Gontard
Autism spectrum disorders (ASD) are defined by persistent deficits in reciprocal social interaction, communication, and language, as well as stereotyped and repetitive behavior. Functional incontinence, as well as ASD are common disorders in childhood. The aim of this systematic review was to give an overview of the co-occurrence of nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI) in ASD, and vice versa, of ASD in children with incontinence. A systematic literature search of the terms "incontinence", "enuresis", and "encopresis" in combination with "autism" or "Asperger" in four databases (Scopus, PubMed, PsycInfo and Web of science) was conducted...
October 10, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28986091/the-role-of-adenotonsillectomy-in-the-treatment-of-primary-nocturnal-enuresis-in-children-a-systematic-review
#12
Kyle Jeffrey Lehmann, Ralph Nelson, Dawn MacLellan, Peter Anderson, Rodrigo L P Romao
INTRODUCTION: Primary nocturnal enuresis (PNE) is a challenging condition for physicians, patients and families. Although the etiology remains unclear, sleep-disordered breathing (SDB) and sleep apnea have been suggested to play an important role. Recent research has suggested a potential therapeutic benefit of adenotonsillectomy (T&A) and surgical management of upper airway obstruction in the treatment of PNE. OBJECTIVE: The aim was to conduct a systematic review of relevant literature to determine the effectiveness of T&A in treating children aged 2-19 years with PNE...
September 6, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28974365/predictors-of-outcome-in-children-and-adolescents-with-overactive-bladder-treated-with-parasacral-transcutaneous-electrical-nerve-stimulation
#13
Anselmo Hoffmann, Clara Sampaio, Ana Aparecida Nascimento, Maria Luiza Veiga, Ubirajara Barroso
BACKGROUND: Parasacral transcutaneous electrical nerve stimulation (TENS) has emerged as an effective treatment for overactive bladder (OAB) in view of its high success rates in improving lower urinary tract symptoms and constipation, with no direct side effects. However, the clinical characteristics associated with the outcomes remain to be established. OBJECTIVE: The aim of this study was to evaluate potential predictors of outcome in children with OAB treated using parasacral TENS...
September 8, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28966673/desmopressin-plus-anticholinergic-agent-in-the-treatment-of-nocturnal-enuresis-a-meta-analysis
#14
Jianyong Yu, Zhaojun Yan, Shiying Zhou, Feng Han, Feng Xiao, Jian Han, Congling Sun
The present study aimed to evaluate the clinical efficacy and safety of combination therapy comprising desmopressin plus anticholinergic agent compared with desmopressin alone for children with nocturnal enuresis (NE). A meta-analysis of 8 eligible studies was performed to analyze the effects of desmopressin plus anticholinergic agent combination therapy and desmopressin monotherapy in the treatment of NE in children. The overall odds ratio (OR) or standardized mean difference (SMD) and 95% confidence interval were calculated for full responders (FR), partial responders (PR), non-responders (NR), the change in the mean number of wet nights and adverse events...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28891253/effect-of-traditional-chinese-and-western-medicine-on-nocturnal-enuresis-in-children-and-its-influencing-factors-a-randomized-controlled-trial
#15
Yanli Ma, Xiaomei Liu, Ying Shen
BACKGROUND: Nocturnal enuresis (NE) is a common pediatric developmental disorder. Desmopressin is frequently used for NE and is an evidence-based therapy.The Suoquan capsule is a Chinese medicine commonly used for treating NE in children but is poorly understood by most scholars. METHODS: A total of 369 children with NE were randomized to receive treatments consisting of Suoquan, desmopressin plus Suoquan, desmopressin, or behavioral interventions for two months...
September 10, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28888814/primary-and-secondary-enuresis-pathophysiology-diagnosis-and-treatment
#16
REVIEW
Bernhard Haid, Serdar Tekgül
CONTEXT: Enuresis is a common and possibly underestimated condition. While 5-10% of school-aged children suffer from the condition, a lack of background knowledge may impede timely child-adapted and successful therapy. OBJECTIVE: To provide a comprehensive overview of the pathophysiology, diagnosis, and treatment of enuresis. EVIDENCE ACQUISITION: Guideline and position papers from the European Society of Pediatric Urology, the European Association of Urology, and the International Children's Continence Society were acquired...
April 2017: European Urology Focus
https://www.readbyqxmd.com/read/28867160/children-with-nocturnal-enuresis-and-attention-deficit-hyperactivity-disorder-a-separate-entity
#17
Larisa Kovacevic, Cortney Wolfe-Christensen, Aliza Rizwan, Hong Lu, Yegappan Lakshmanan
INTRODUCTION: There is ongoing debate about whether nocturnal enuresis (NE) is affected by the presence of attention deficit hyperactivity disorder (ADHD) in children. Clarifying this relationship could categorize them as a separate entity, potentially requiring a different management from enuretic children without ADHD. AIMS: To study whether (1) children with ADHD exhibited greater severity of enuresis and associated voiding symptoms compared with children without ADHD, (2) whether there was a difference in enuretic response to treatment between children with/without ADHD, (3) whether previously prescribed medication for ADHD affected severity of enuresis or voiding symptoms, and response to treatment...
August 3, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28828529/clinical-management-of-nocturnal-enuresis
#18
Eberhard Kuwertz-Bröking, Alexander von Gontard
Nocturnal enuresis (NE) is a common health problem. Approximately 10% of 7-year-old children wet the bed regularly during sleep. Enuresis can be categorized into monosymptomatic (MEN) and nonmonosymptomatic (NMEN) forms. MEN occurs without any other symptoms of bladder dysfunction. NMEN is associated with dysfunction of the lower urinary tract with or without daytime incontinence. The rate of comorbid gastrointestinal, behavioral, and emotional disorders is elevated depending upon the subtype of NE. A careful clinical history is fundamental to the evaluation of enuresis...
August 21, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28817922/re-risk-factors-and-functional-abnormalities-associated-with-adult-onset-secondary-nocturnal-enuresis-in-women
#19
Alan J Wein
No abstract text is available yet for this article.
September 2017: Journal of Urology
https://www.readbyqxmd.com/read/28747281/transcutaneous-electrical-nerve-stimulation-in-children-with-monosymptomatic-nocturnal-enuresis-a-randomized-double-blind-placebo-controlled-study
#20
Cecilie Siggaard Jørgensen, Konstantinos Kamperis, Luise Borch, Britt Borg, Søren Rittig
PURPOSE: In a third of all children with monosymptomatic nocturnal enuresis their condition is refractory to first line treatments. Transcutaneous electrical nerve stimulation has been documented to be efficacious in children with daytime incontinence. We investigated the effect of transcutaneous electrical nerve stimulation in children with monosymptomatic nocturnal enuresis without nocturnal polyuria. MATERIALS AND METHODS: Children with monosymptomatic nocturnal enuresis (3 or more wet nights per week) and no nocturnal polyuria were randomized to treatment with active or sham transcutaneous electrical nerve stimulation involving 1-hour sessions twice daily for 10 weeks in a double-blind design...
September 2017: Journal of Urology
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