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nocturnal enuresis

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https://www.readbyqxmd.com/read/29456117/extraordinary-daytime-only-urinary-frequency-in-childhood-prevalence-diagnosis-and-management
#1
Pierluigi Marzuillo, Mario Diplomatico, Rosaria Marotta, Laura Perrone, Emanuele Miraglia Del Giudice, Cesare Polito, Angela La Manna, Stefano Guarino
INTRODUCTION: Since standardization of the ICCS terminology, only two small case series of children with extraordinary daytime only urinary frequency (EDOUF) have been published. The aims of the present study were i) to describe a large cohort of children affected by EDOUF, to evaluate its rate among the main micturition pediatric disturbances, and to determine if there is different EDOUF onset among seasons; ii) to investigate possible associations with urodynamic abnormalities by non-invasive techniques; iii) to evaluate whether postponing micturition exercise (PME) can objectively verify the anamnestic data hinting at the EDOUF diagnosis; and iv) to determine the effect of postponing micturition at home...
February 9, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29452905/voiding-school-as-a-treatment-for-daytime-incontinence-or-enuresis-assessing-the-effectiveness-of-intervention-by-measuring-changes-in-wetting-episodes
#2
A Saarikoski, R Koppeli, S Taskinen, A Axelin
BACKGROUND: Most urotherapy interventions are planned for children with daytime incontinence or symptoms, and are based on individual education. This study conducted a voiding school (VS) program with groups of 4-6 children with daytime incontinence or enuresis with or without daytime symptoms. OBJECTIVE: The aim of this quasi-experimental study with a one-group pretest-posttest design was to assess the effectiveness of the VS intervention for treating children's daytime incontinence or enuresis...
February 5, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29447815/pre-and-post-operative-evaluation-of-the-frequency-of-nocturnal-enuresis-and-modified-pediatric-epworth-scale-in-pediatric-obstructive-sleep-apnea-patients
#3
Kerem Sami Kaya, Bilge Türk, Zeynep Nur Erol, Pınar Akova, Berna Uslu Coşkun
OBJECTIVE: To investigate the beneficial effect of adenotonsillectomy (AT) on nocturnal enuresis (NE) in children with adenotonsillar hypertrophy and evaluate the Modified Pediatric Epworth Scale (MPES). METHODS: This was a prospective study comparing preoperative and postoperative evaluation of the frequency of NE and MPES in pediatric obstructive sleep apnea (OSA). A questionnaire on NE history was prepared based on the Turkish Enuresis Guidelines. NE histories were evaluated pre- and postoperatively on the first month and third month, respectively...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29445339/population-pharmacokinetic-modeling-of-a-desmopressin-oral-lyophilisate-in-growing-piglets-as-a-model-for-the-pediatric-population
#4
Elke Gasthuys, An Vermeulen, Siska Croubels, Joske Millecam, Stijn Schauvliege, Thomas van Bergen, Pauline De Bruyne, Johan Vande Walle, Mathias Devreese
Desmopressin is used to treat primary nocturnal enuresis in children. Over the years, various formulations of desmopressin were commercialized of which the sublingual melt tablet is preferred in the pediatric population, despite the lack of full PK studies in this population. A full PK study was performed in growing conventional piglets to evaluate if this juvenile animal model can provide supplementary information to complement the information gap in the pediatric population. A desmopressin sublingual melt tablet (120 μg) was administered to 32 male piglets aged 8 days, 4 weeks, 7 weeks, and 6 months (each group n = 8)...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29428322/study-of-the-profile-of-behavioral-problems-and-quality-of-life-indexes-in-a-pediatric-cohort-of-monosymptomatic-enuresis
#5
Guilherme Jorge Sousa E Silva, Simone Nascimento Fagundes Sammour, Alexandre Archanjo Ferraro, Vera Hermina Kalika Koch
OBJECTIVE: To evaluate and correlate, before and after the therapeutic intervention, the behavioral problem scores evaluated by the CBCL/6-18 questionnaire and the quality of life indexes evaluated by the PedsQL™ 4.0 in patients with monosymptomatic nocturnal enuresis. METHOD: After the initial evaluation and completion of the CBCL/6-18 questionnaire, a multidisciplinary evaluation and completion of the PedsQL™ 4.0 questionnaire was performed. Of the initially evaluated 140 children and adolescents aged 6-16 years, 58 were excluded due to non-monosymptomatic enuresis or associated comorbidities...
February 8, 2018: Jornal de Pediatria
https://www.readbyqxmd.com/read/29376448/desmopressin-and-nocturnal-voiding-dysfunction-clinical-evidence-and-safety-profile-in-the-treatment-of-nocturia
#6
Eric Chung
Nocturia is a common urinary condition experienced by both men and women. While desmopressin has historically been utilized to treat conditions such as central diabetes insipidus and primary nocturnal enuresis, there is an increased interest in the use of desmopressin in the management of adult nocturia. Areas covered: This article provides a review on the pathophysiology of nocturia and the clinical outcomes and safety profile of desmopressin in the management of adult nocturnal voiding dysfunction. Expert opinion: To date, desmopressin is the only anti-diuretic hormone that is approved for nocturia...
January 29, 2018: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29324571/physical-activity-patterns-and-sedentary-behavior-in-older-women-with-urinary-incontinence-an-accelerometer-based-study
#7
Christine M Chu, Kavita D Khanijow, Kathryn H Schmitz, Diane K Newman, Lily A Arya, Heidi S Harvie
PURPOSE: Objective physical activity data for women with urinary incontinence are lacking. We investigated the relationship between physical activity, sedentary behavior, and the severity of urinary symptoms in older community-dwelling women with urinary incontinence using accelerometers. MATERIALS AND METHODS: This is a secondary analysis of a study that measured physical activity (step count, moderate-to-vigorous physical activity time) and sedentary behavior (percentage of sedentary time, number of sedentary bouts per day) using a triaxial accelerometer in older community-dwelling adult women not actively seeking treatment of their urinary symptoms...
January 10, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29260376/desmopressin-use-in-pediatric-nocturnal-enuresis-patients-is-there-a-sex-difference-in-prescription-patterns
#8
Marie Krarup Schroeder, K V Juul, B Mahler, J P Nørgaard, S Rittig
Desmopressin is a long-established treatment for nocturnal enuresis with clear guidelines regarding its usage. A sex difference in renal sensitivity has recently been reported in adults. The objective of this study was to investigate real-life desmopressin prescription in the Danish pediatric population, and prescription patterns which may reflect a sex difference in pediatric usage. Formulation, dose, treatment duration, and safety (hyponatremia) were investigated. 40,596 children received 214,220 desmopressin prescriptions between 2004 and 2011 in the Danish National Prescription Registry...
December 19, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29217876/nocturnal-enuresis-in-india-are-we-diagnosing-and-managing-correctly
#9
REVIEW
N M Reddy, H Malve, R Nerli, P Venkatesh, I Agarwal, V Rege
Nocturnal enuresis is a common problem affecting school-aged children worldwide. Although it has significant impact on child's psychology, it is always under-recognized in India and considered as a condition which will outgrow with advancing age. Nocturnal enuresis classified as primary or secondary and monosymptomatic or nonmonosymptomatic. Factors that cause enuresis include genetic factors, bladder dysfunction, psychological factors, and inappropriate antidiuretic hormone secretion, leading to nocturnal polyuria...
November 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/29198064/claiming-desmopressin-therapeutic-equivalence-in-children-requires-pediatric-data-a-population-pkpd-analysis
#10
Robin Michelet, Lien Dossche, Charlotte Van Herzeele, Jan Van Bocxlaer, An Vermeulen, Johan Vande Walle
PURPOSE: For a new formulation of a drug, only pharmacokinetic bioequivalence with the original formulation has to be demonstrated in healthy, young adults. However, "children are not small adults," and to guarantee a safe and effective treatment, age-adapted drug development is required. Desmopressin, a vasopressin analogue prescribed for nocturnal enuresis in children, was studied as an example formulation first developed in adults and then extrapolated to a pediatric indication. METHODS: Population pharmacokinetic and pharmacodynamic modeling was used to analyze previously published desmopressin data of 18 children suffering from nocturnal enuresis...
December 3, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29175540/the-effect-of-family-assistance-to-wake-children-with-monosymptomatic-enuresis-in-alarm-therapy-a-pilot-study
#11
Shoji Tsuji, Chikushi Suruda, Takahisa Kimata, Jiro Kino, Sohsaku Yamanouchi, Kazunari Kaneko
PURPOSE: Alarm therapy is widely used as first-line treatment for nocturnal enuresis (NE). However, some children do not wake when nocturnal urination activates the alarm. It is currently unclear whether waking the child when the alarm is activated improves the efficacy of alarm therapy. This study aimed to investigate the efficacy of alarm therapy for NE when children do not wake in response to the sound and their parents do not wake them. MATERIALS AND METHODS: Detailed information regarding incontinence was retrospectively obtained from 78 of 112 patients who underwent alarm therapy between 2006 and 2016 and completed a questionnaire and a 14-day bladder diary...
November 23, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29174376/evidence-of-reduced-bladder-capacity-during-nighttime-in-children-with-monosymptomatic-nocturnal-enuresis
#12
B Borg, K Kamperis, L H Olsen, S Rittig
INTRODUCTION: Bladder capacity in children with nocturnal enuresis is assessed by maximal voided volumes (MVV) obtained through daytime frequency volume (FV) charts. Although a degree of association has been demonstrated, daytime MVV does not consistently correspond with the nocturnal bladder capacity (NBC) in monosymptomatic nocturnal enuresis (MNE). It was hypothesized that isolated reduced NBC is a common phenomenon in children with nocturnal enuresis, despite normal daytime bladder function...
October 27, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29151300/the-effect-of-antidiuretic-hormone-on-urine-and-serum-electrolyte-levelsin-children-with-primary-monosymptomatic-nocturnal-enuresis
#13
(no author information available yet)
Background/aim: The data concerning the effects of desmopressin on water/electrolyte disturbances of children with primary monosymptomatic nocturnal enuresis (PMNE) are limited. In the present study we aimed to evaluate the effect and tolerability of desmopressin on blood and urine electrolytes and osmolality in PMNE.Materials and methods: Thirty-five children with PMNE between the ages of 5 and 15 participated in the study. Patients collected urine during the daytime and acknowledged the night time fluid restriction before starting to use the desmopressin tablets...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29123651/recent-advances-in-managing-and-understanding-enuresis
#14
REVIEW
Charlotte Van Herzeele, Johan Vande Walle, Karlien Dhondt, Kristian Vinter Juul
Enuresis, particularly in children during sleep, can be a debilitating condition, affecting the quality of life of the child and his or her family. The pathophysiology of nocturnal enuresis, though not clear, revolves around the inter-related mechanisms of overactive bladder, excessive nocturnal urine production, and sleep fragmentation. The first mechanism is more related to isolated nocturnal voiding, whereas the latter two are more related to nocturnal enuresis, in which circadian variations in arginine vasopressin hormone play a key role...
2017: F1000Research
https://www.readbyqxmd.com/read/29067072/behavioral-factors-for-predicting-severity-of-enuresis-and-treatment-responses-in-different-compliance-groups-receiving-behavioral-therapy
#15
Yanli Ma, Xiaomei Liu, Ying Shen
OBJECTIVE: To investigate behavioral factors for predicting severity of nocturnal enuresis and compare response rates in different compliance groups of behavioral interventions. METHODS: Three hundred eleven children diagnosed with nocturnal enuresis were enrolled. This study was conducted at Beijing Children's Hospital affiliated to the Capital Medical University from September 2016 to December 2016. Correlation of severity of enuresis and behavioral factors was investigated...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29060371/a-prospective-study-of-examining-physiological-signals-for-estimating-occurrence-of-nocturnal-enuresis
#16
Junhyung Moon, Sangyeop Lee, Taeho Lee, Saewon Kye, Yong Seung Lee, Seung-Chul Shin, Kyoungwoo Lee
The nocturnal enuresis is challenging due to the increased social activities of the children. This disorder significantly bothers both the children and their parents in psychological, behavioral, social, and financial manners. However, the primary treatments have limitations and further are not able to completely cure the disorder. In order to reduce pain and burdens of patients and their parents, it is important to accurately estimate when the enuretic incident occurs in advance. For the estimation, we have comprehensively investigated various studies of the nocturnal enuresis in the diverse fields...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29055129/desmopressin-for-treating-nocturia-in-men
#17
REVIEW
Julia Han, Jae Hung Jung, Caitlin J Bakker, Mark H Ebell, Philipp Dahm
BACKGROUND: Nocturia is the bothersome symptom of awakening one or more times per night to void. Desmopressin is a commonly used medication for treating nocturia. OBJECTIVES: To assess the effects of desmopressin as compared to other interventions in the treatment of nocturia in men. SEARCH METHODS: We performed a comprehensive search of medical literature with no restrictions on the language of publication or publication status. The date of the latest search of all databases was August 2017...
October 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29045258/early-behavioral-risks-of-childhood-and-adolescent-daytime-urinary-incontinence-and-nocturnal-enuresis
#18
Monica M A Vasconcelos, Patricia East, Estela Blanco, Emily S Lukacz, Gabriela Caballero, Betsy Lozoff, Sheila Gahagan
OBJECTIVE: To investigate whether infant temperament and childhood internalizing, externalizing, and inattention symptoms increase the likelihood of daytime urinary incontinence or nocturnal enuresis at 10 years and adolescence (11.9-17.8 years). METHOD: Data were from a longitudinal cohort of 1119 healthy Chilean children. We assessed behavioral symptoms at infancy, 5 years, and 10 years and their relationship with subsequent daytime urinary incontinence and nocturnal enuresis...
November 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29019014/incontinence-in-autism-spectrum-disorder-a-systematic-review
#19
REVIEW
Justine Niemczyk, C Wagner, A von Gontard
Autism spectrum disorders (ASD) are defined by persistent deficits in reciprocal social interaction, communication, and language, as well as stereotyped and repetitive behavior. Functional incontinence, as well as ASD are common disorders in childhood. The aim of this systematic review was to give an overview of the co-occurrence of nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI) in ASD, and vice versa, of ASD in children with incontinence. A systematic literature search of the terms "incontinence", "enuresis", and "encopresis" in combination with "autism" or "Asperger" in four databases (Scopus, PubMed, PsycInfo and Web of science) was conducted...
October 10, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28986091/the-role-of-adenotonsillectomy-in-the-treatment-of-primary-nocturnal-enuresis-in-children-a-systematic-review
#20
Kyle Jeffrey Lehmann, Ralph Nelson, Dawn MacLellan, Peter Anderson, Rodrigo L P Romao
INTRODUCTION: Primary nocturnal enuresis (PNE) is a challenging condition for physicians, patients and families. Although the etiology remains unclear, sleep-disordered breathing (SDB) and sleep apnea have been suggested to play an important role. Recent research has suggested a potential therapeutic benefit of adenotonsillectomy (T&A) and surgical management of upper airway obstruction in the treatment of PNE. OBJECTIVE: The aim was to conduct a systematic review of relevant literature to determine the effectiveness of T&A in treating children aged 2-19 years with PNE...
September 6, 2017: Journal of Pediatric Urology
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