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https://www.readbyqxmd.com/read/28549330/impact-of-post-traumatic-stress-disorder-on-oral-health
#1
Ana Cristina de Oliveira Solis, Álvaro Cabral Araújo, Felipe Corchs, Marcio Bernik, Érica Panzani Duran, Cláudio Silva, Francisco Lotufo-Neto
BACKGROUND: The stress experienced as an intense and traumatic event can increase the odds of orofacial pain, affect the biomechanics of masticatory system and compromise the periodontal health. This study was conducted to investigate the impact of post-traumatic stress disorder (PTSD) on oral health. METHODS: A case-control study with a convenience sample was designed. Probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing, and plaque were recorded at 6 sites per tooth...
May 20, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28545012/the-long-term-association-of-ocd-and-depression-and-its-moderators-a-four-year-follow-up-study-in-a-large-clinical-sample
#2
L Tibi, P van Oppen, A J L M van Balkom, M Eikelenboom, J Rickelt, K R J Schruers, G E Anholt
BACKGROUND: Depression is the most common comorbidity in obsessive-compulsive disorder (OCD). However, the mechanisms of depressive comorbidity in OCD are poorly understood. We assessed the directionality and moderators of the OCD-depression association over time in a large, prospective clinical sample of OCD patients. METHODS: Data were drawn from 382 OCD patients participating at the Netherlands Obsessive-Compulsive Disorder Association (NOCDA) study. Cross-lagged, structural equation modeling analyses were used to assess the temporal association between OCD and depressive symptoms...
April 7, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28542243/covalent-dye-attachment-influences-the-dynamics-and-conformational-properties-of-flexible-peptides
#3
Manuel P Luitz, Anders Barth, Alvaro H Crevenna, Rainer Bomblies, Don C Lamb, Martin Zacharias
Fluorescence spectroscopy techniques like Förster resonance energy transfer (FRET) and fluorescence correlation spectroscopy (FCS) have become important tools for the in vitro and in vivo investigation of conformational dynamics in biomolecules. These methods rely on the distance-dependent quenching of the fluorescence signal of a donor fluorophore either by a fluorescent acceptor fluorophore (FRET) or a non-fluorescent quencher, as used in FCS with photoinduced electron transfer (PET). The attachment of fluorophores to the molecule of interest can potentially alter the molecular properties and may affect the relevant conformational states and dynamics especially of flexible biomolecules like intrinsically disordered proteins (IDP)...
2017: PloS One
https://www.readbyqxmd.com/read/28541238/attitudes-of-psychology-students-to-depression-and-its-treatment-implications-for-clinical-practice
#4
M Economou, L E Peppou, K Geroulanou, K Kontoangelos, A Prokopi, A Pantazi, A Zervakaki, C N Stefanis
Stigma and mental health literacy affect access to and quality of treatment of major depression. Though mental health professionals seem better able to recognize major depression than the general public, they often hold similarly stigmatizing attitudes towards people suffering from the disorder. These attitudes are shaped jointly by the public stigma attached to mental illnesses as well as by the content and delivery of mental health professionals' undergraduate training. In line with this, the present study aimed to explore psychology students' ability to recognize major depression, their attitudes towards the disorder, and their views surrounding helpfulness of various interventions...
January 2017: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/28537850/predictors-of-clinical-outcomes-in-sexually-abused-adolescents
#5
Lotem Tocker, Galit Ben-Amitay, Netta Horesh-Reinman, Michal Lask, Paz Toren
This cross-sectional, case control study examines the association between child sexual abuse and interpersonal and intrapersonal outcomes among 54 adolescents, examining specific clinical measures (depression, anxiety, dissociation, and posttraumatic stress disorder, attachment patterns, self-esteem, self-disclosure, and family environment characteristics). The research results point to a correlation between sexual abuse and higher levels of the clinical measures. In addition, a correlation was found between sexual abuse and level of avoidant attachment, self-esteem, and family environment characteristics...
May 2017: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/28537091/convergence-between-observations-and-interviews-in-clinical-diagnosis-of-reactive-attachment-disorder-and-disinhibited-social-engagement-disorder
#6
Hans Peter Giltaij, Paula Sophia Sterkenburg, Carlo Schuengel
OBJECTIVE: A comprehensive approach is needed for diagnosing disordered attachment behavior due to the multifaceted nature of attachment. Differences between various indicators can pose a challenge for deciding on the proper diagnosis. This study assessed the convergence between clinical interview assessment and observation-based clinical diagnosis, and their linkages with inadequate care. METHOD: Participating children ( N = 55) had intelligence quotients (IQs) between 50 and 85 and were referred for psychiatric consultation...
May 1, 2017: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/28535839/separation-from-parents-during-childhood-trauma-predicts-adult-attachment-security-and-post-traumatic-stress-disorder
#7
R A Bryant, M Creamer, M O'Donnell, D Forbes, K L Felmingham, D Silove, G Malhi, M van Hoof, A C McFarlane, A Nickerson
BACKGROUND: Prolonged separation from parental support is a risk factor for psychopathology. This study assessed the impact of brief separation from parents during childhood trauma on adult attachment tendencies and post-traumatic stress. METHOD: Children (n = 806) exposed to a major Australian bushfire disaster in 1983 and matched controls (n = 725) were assessed in the aftermath of the fires (mean age 7-8 years) via parent reports of trauma exposure and separation from parents during the fires...
May 24, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28523529/s-nitrosylation-regulates-cell-survival-and-death-in-the-central-nervous-system
#8
Yoshiki Koriyama, Ayako Furukawa
Nitric oxide (NO), which is produced from nitric oxide synthase, is an important cell signaling molecule that is crucial for many physiological functions such as neuronal death, neuronal survival, synaptic plasticity, and vascular homeostasis. This diffusible gaseous compound functions as an effector or second messenger in many intercellular communications and/or cell signaling pathways. Protein S-nitrosylation is a posttranslational modification that involves the covalent attachment of an NO group to the thiol side chain of select cysteine residues on target proteins...
May 18, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28523433/structural-and-functional-roles-of-ether-lipids
#9
REVIEW
John M Dean, Irfan J Lodhi
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This seemingly simple biochemical change has profound structural and functional implications. Notably, the tendency of ether lipids to form non-lamellar inverted hexagonal structures in model membranes suggests that they have a role in facilitating membrane fusion processes...
May 18, 2017: Protein & Cell
https://www.readbyqxmd.com/read/28523385/attention-deficit-hyperactivity-disorder-adhd-symptoms-in-children-adopted-from-poland-and-their-atypical-association-patterns-a-bayesian-approach
#10
Donna A de Maat, Sandra Knuiman, Catharina H A M Rijk, René A C Hoksbergen, Anneloes L van Baar
Although high rates of attention-deficit hyperactivity disorder (ADHD) symptoms have been observed among internationally adopted children, research on these symptoms in Polish adoptees is lacking. Therefore, we examined ADHD symptoms in Polish adoptees and their relationship to pre-adoptive risk factors, that is, time in institutional care, early deprivation, and prenatal alcohol exposure. We further compared the association patterns and gender distribution of ADHD symptoms in children adopted from Poland to those reported in the literature for ADHD symptoms in non-adopted children...
May 18, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28521314/romantic-relationships-of-people-with-borderline-personality-a-narrative-review
#11
Sara Navarro-Gómez, Álvaro Frías, Carol Palma
BACKGROUND: Romantic relationships are one of the most interesting areas of interpersonal functioning in people with borderline personality. The aim of this narrative review was to synthesise empirical findings on this issue. SAMPLING AND METHODS: The PubMed and PsycINFO databases were searched for pertinent materials published between 1980 and March 2016. Thirty articles met the inclusion criteria. RESULTS: Several longitudinal and cross-sectional studies showed that people with borderline personality disorder (BPD) or BPD traits had more - but less prolonged - romantic relationships than people without BPD...
May 19, 2017: Psychopathology
https://www.readbyqxmd.com/read/28509394/room-temperature-oligomeric-discotic-nematic-liquid-crystals-over-a-wide-temperature-range-structure-property-relationships
#12
Santanu Kumar Pal, Monika Gupta, Santosh Prasad Gupta, Subhransu Sekhar Mohapatra, Surajit Dhara
Design and synthesis of three room-temperature discotic nematic (ND) liquid crystals (LCs) is presented consisting of an azobenzene core attached to which are four pentaalkynylbenzene (PA) units via flexible alkyl spacers. The presence of short azo linking group provides more disorder in the system, thereby reducing the packing efficiency among the PA units and resulting into the formation of a room-temperature ND phase over a wide temperature range. Dielectric constant and birefringence studies were performed to gain further insights into the physical properties of the mesophase...
May 16, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28507244/inhibition-of-staphylococcus-aureus-cell-wall-biosynthesis-by-desleucyl-oritavancin-a-quantitative-peptidoglycan-composition-analysis-by-mass-spectrometry
#13
James D Chang, Erin E Foster, Aanchal N Thadani, Alejandro J Ramirez, Sung Joon Kim
Oritavancin is a lipoglycopeptide antibiotic that exhibits potent activities against vancomycin-resistant Gram-positive pathogens. Oritavancin differs from vancomycin by a hydrophobic side chain attached to the drug disaccharide, which forms a secondary-binding site to enable oritavancin binding to the cross-linked peptidoglycan in cell wall. The mode of action of secondary-binding site was investigated by measuring the changes in the peptidoglycan composition of Staphylococcus aureus grown in presence of desleucyl-oritavancin at sub-inhibitory concentration using liquid chromatography-mass spectrometry (LC-MS)...
May 15, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28503141/addiction-as-an-attachment-disorder-white-matter-impairment-is-linked-to-increased-negative-affective-states-in-poly-drug-use
#14
Human-Friedrich Unterrainer, Michaela Hiebler-Ragger, Karl Koschutnig, Jürgen Fuchshuber, Sebastian Tscheschner, Maria Url, Jolana Wagner-Skacel, Eva Z Reininghaus, Ilona Papousek, Elisabeth M Weiss, Andreas Fink
Substance use disorders (SUD) have been shown to be linked to various neuronal and behavioral impairments. In this study, we investigate whether there is a connection between the integrity of white matter (WM) and attachment styles as well as different affective states including spirituality in a group of patients diagnosed for poly-drug use disorder (PUD) in comparison to non-clinical controls. A total sample of 59 right-handed men, comprising the groups of patients with PUD (n = 19), recreational drug-using individuals (RUC; n = 20) as well as non-drug using controls were recruited (NUC; n = 20)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28502270/insecure-attachment-predicts-depression-and-death-anxiety-in-advanced-cancer-patients
#15
Katharina Scheffold, Rebecca Philipp, Susan Koranyi, Dorit Engelmann, Frank Schulz-Kindermann, Martin Härter, Anja Mehnert
OBJECTIVE: The prevalence of depression as well as adjustment and anxiety disorders is high in advanced cancer patients, and research exploring intraindividual factors leading to high psychological distress is underrepresented. Cancer patients' feelings about security and trust in their healthcare providers have a significant influence on how they deal with their disease. The perception of social support is affected by patients' attachment styles and influences their reactions to feelings of dependency and loss of control...
May 15, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28502220/dynamic-assessment-of-visual-neglect-the-mobility-assessment-course-as-a-diagnostic-tool
#16
Antonia F Ten Brink, Johanna M A Visser-Meily, Tanja C W Nijboer
INTRODUCTION: Visual neglect is a frequent disorder following stroke and is often diagnosed by neuropsychological assessment. However, paper-and-pencil tasks have low predictive value as they lack sensitivity to capture neglect in complex, dynamic situations, such as activities of daily living. Aims of the current study were to assess the feasibility of the Mobility Assessment Course (MAC), a visual search multitask, to assess neglect, and its relation with existing neglect tasks. METHOD: Stroke patients admitted for inpatient rehabilitation and healthy controls were tested with the MAC in different corridors...
May 14, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28501506/defective-neuronal-migration-and-inhibition-of-bipolar-to-multipolar-transition-of-migrating-neural-cells-by-mesoderm-specific-transcript-mest-in-the-developing-mouse-neocortex
#17
Liting Ji, Kausik Bishayee, Ali Sadra, Seunghyuk Choi, Wooyul Choi, Sungho Moon, Eek-Hoon Jho, Sung-Oh Huh
Brain developmental disorders such as lissencephaly can result from faulty neuronal migration and differentiation during the formation of the mammalian neocortex. The cerebral cortex is a modular structure, where developmentally, newborn neurons are generated as a neuro-epithelial sheet and subsequently differentiate, migrate and organize into their final positions in the cerebral cortical plate via a process involving both tangential and radial migration. The specific role of Mest, an imprinted gene, in neuronal migration has not been previously studied...
May 10, 2017: Neuroscience
https://www.readbyqxmd.com/read/28500976/personality-disparity-in-chronic-regional-and-widespread-pain
#18
Mei-Chung Chang, Po-Fei Chen, For-Wey Lung
Chronic pain has high comorbidity with psychiatric disorders, therefore, better understanding of the relationship between chronic pain and mental illness is needed. This study aimed to investigate the pathway relationships among parental attachment, personality characteristics, alexithymic trait and mental health in patients with chronic widespread pain, those with chronic regional pain, and controls. Two hundred and thirty participants were recruited. The parental Bonding Inventory, Eysenck Personality Inventory (EPI), 20-item Toronto Alexithymia Scale (TAS-20), Chinese Health Questionnaire, and Short-Form 36 were filled out...
April 27, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28497401/using-a-film-intervention-in-early-addiction-treatment-a-qualitative-analysis-of-process
#19
Ingerid Elgesem Bjelland, Ayna Johansen, Farnad Darnell, Håvar Brendryen
PURPOSE: There is a need for knowledge about how self-help materials can be made useful in treatment for Substance Abuse Disorders (SUD), as a supplement to ongoing treatment, or as independent tools for change. OBJECTIVE: In this study, we explored the use of self-help films in early addiction treatment, taking into account both patient and therapist perspectives, as well as dyadic functions. We explored how active mechanisms might be related to intervention format and implementation context...
May 11, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28496420/impaired-maintenance-of-interpersonal-synchronization-in-musical-improvisations-of-patients-with-borderline-personality-disorder
#20
Katrien Foubert, Tom Collins, Jos De Backer
Borderline personality disorder (BPD) is a serious and complex mental disorder with a lifetime prevalence of 5.9%, characterized by pervasive difficulties with emotion regulation, impulse control, and instability in interpersonal relationships and self-image. Impairments in interpersonal functioning have always been a prominent characteristic of BPD, indicating a need for research to identify the specific interpersonal processes that are problematic for diagnosed individuals. Previous research has concentrated on self-report questionnaires, unidirectional tests, and experimental paradigms wherein the exchange of social signals between individuals was not the focus...
2017: Frontiers in Psychology
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