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SPONDYLOLISTHESIS MECHANISM

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https://www.readbyqxmd.com/read/29609581/mild-not-severe-disc-degeneration-is-implicated-in-the-progression-of-bilateral-l5-spondylolysis-to-spondylolisthesis
#1
Vivek A S Ramakrishna, Uphar Chamoli, Luke L Viglione, Naomi Tsafnat, Ashish D Diwan
BACKGROUND: Spondylolytic (or lytic) spondylolisthesis is often associated with disc degeneration at the index-level; however, it is not clear if disc degeneration is the cause or the consequence of lytic spondylolisthesis. The main objective of this computed tomography based finite element modelling study was to examine the role of different grades of disc degeneration in the progression of a bilateral L5-lytic defect to spondylolisthesis. METHODS: High-resolution computed tomography data of the lumbosacral spine from an anonymised healthy male subject (26 years old) were segmented to build a 3D-computational model of an INTACT L1-S1 spine...
April 2, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29592979/spondylodiscitis-in-a-54-year-old-female-scuba-diver
#2
Neil Tuttle, Alexandra Brelis, Rachel Brereton, Kerrie Evans
A 54-year-old woman presented to a Sports Physician with a 4-year history of haemochromatosis, and she had a medical history that included a congenital spondylolisthesis resulting in a fusion of L4-S1 at age 16 years, episodic mechanical low back pain and an absence of other significant musculoskeletal symptoms. On presentation, she reported 18 months of severe low back pain that started after a scuba diving trip. After the onset of this low back pain, she developed gastrointestinal symptoms from Salmonella The gastrointestinal symptoms improved with a course of antibiotics, but the back pain persisted in spite of analgesics, non-steroidal anti-inflammatories and several attempts at different conservative management...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29383486/focal-disorders-of-the-spine-with-compensatory-deformities-how-to-define-them
#3
REVIEW
Andrea Redaelli, Pedro Berjano, Max Aebi
PURPOSE: In this paper, the authors propose classifying the epiphenomenon of spinal deformity in two different categories: structural deformity, when the main driver of the observed deformity is a fixed and stiff alteration of the spinal segments, and compensatory deformity, which includes cases where the observed deformity is due to focal abnormalities. This last category comprises, but is not limited to, spinal stenosis, spondylolisthesis, disc herniation, infection or tumor, hip disease or neurological disease (such as Parkinson's disease)...
February 2018: European Spine Journal
https://www.readbyqxmd.com/read/29332744/how-many-physical-therapy-sessions-are-required-to-reach-a-good-outcome-in-symptomatic-lumbar-spondylolisthesis-a-retrospective-study
#4
Silvano Ferrari, Jorge Hugo Villafañe, Pedro Berjano, Carla Vanti, Marco Monticone
BACKGROUND: There is a lack of conclusive information about the optimal dosage of physical therapy treatments in Spondylolisthesis (SPL) patients. PURPOSE: The present study attempted to evaluate the comparative effectiveness of two different doses in reaching similar clinical outcomes. METHODS: A retrospective cohort study of 64 consecutive patients admitted for physical therapy with symptomatic lumbar grade I SPL (42 ± 15years, 57% female) was conducted...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29288862/variability-in-surgical-treatment-of-spondylolisthesis-among-spine-surgeons
#5
Daniel Lubelski, Vincent J Alentado, Seth K Williams, Colin O'Rourke, Nancy A Obuchowski, Jeffrey C Wang, Michael P Steinmetz, Alfred J Melillo, Edward C Benzel, Michael T Modic, Robert Quencer, Thomas E Mroz
BACKGROUND: There are a multitude of treatments for low-grade lumbar spondylolisthesis. There are no clear guidelines for the optimal approach. OBJECTIVE: To identify the surgical treatment patterns for spondylolisthesis among United States spine surgeons. METHODS: 445 spine surgeons in the United States completed a survey of clinical/radiographic case scenarios on patients with lumbar spondylolisthesis with neurogenic claudication with (S+BP) or without (S-BP) associated mechanical back pain...
March 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29259641/icariin-prevents-il-1-%C3%AE-induced-apoptosis-in-human-nucleus-pulposus-via-the-pi3k-akt-pathway
#6
Xiangyu Deng, Wei Wu, Hang Liang, Donghua Huang, Doudou Jing, Dong Zheng, Zengwu Shao
Purpose: To explore the effect and possible mechanism of icariin, a prenylated flavonol glycoside derived from the Chinese herb Epimedium sagittatum that was applied to IL-1 β pretreated human nucleus pulposus (NP) cells. Methods: Human NP cells were isolated from intervertebral discs of patients with scoliosis and lumbar spondylolisthesis. The cells were divided into five groups: A (blank control); B (20 ng/ml IL-1 β ); C (20 ng/ml IL-1 β + 20  μ M icariin); D (20  μ M icariin + 20 ng/ml IL-1 β + 25  μ M LY294002); E (20 ng/ml IL-1 β + 25  μ M LY294002)...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28942019/failure-patterns-in-standalone-anterior-cervical-discectomy-and-fusion-implants
#7
Fernando Alonso, Tarush Rustagi, Cameron Schmidt, Daniel C Norvell, R Shane Tubbs, Rod J Oskouian, Jens R Chapman, Christian Fisahn
BACKGROUND: Anterior cervical discectomy and fusion is commonly performed using an allograft or autograft implant and anterior screw-supported plate. There has been an increase in the use of standalone cage devices due to ease of use and studies suggesting a lower rate of acute postoperative dysphagia. We review our experience with standalone cage devices and identify risk factors, patterns of failure, and revision surgery approaches. METHODS: We performed a retrospective case series of patients treated at a single tertiary care institution between March 2014 and March 2015...
December 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28843706/variation-of-facet-joint-orientation-and-tropism-in-lumbar-degenerative-spondylolisthesis-and-disc-herniation-at-l4-l5-a-systematic-review-and-meta-analysis
#8
REVIEW
Ziyang Liu, Yuchen Duan, Xin Rong, Beiyu Wang, Hua Chen, Hao Liu
Although degenerative spondylolisthesis (DS) and lumber disc herniation (LDH) are common causes of back pain, the associations between the lumbar facet joint angle orientation and tropism in these conditions are still contentious. The objective of the meta-analysis was to identify the role of facet joint orientation and tropism on the development of lumbar degenerative disease, including DS and LDH. Electronic searches of PubMed and Embase were conducted up to April 2017. P value<0.05 was regarded as significant...
October 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28623897/altered-somatosensory-profile-according-to-quantitative-sensory-testing-in-patients-with-degenerative-lumbar-spine-disorders-scheduled-for-surgery
#9
Yvonne Lindbäck, Hans Tropp, Paul Enthoven, Björn Gerdle, Allan Abbott, Birgitta Öberg
BACKGROUND: Somatosensory profiling in affected and non-affected body regions can strengthen our insight regarding the underlying pain mechanisms, which can be valuable in treatment decision making and to improve outcomes, in patients with degenerative lumbar spine disorders pre-surgery. The aim was to describe somatosensory profiles in patients with degenerative lumbar spine disorders, to identify the proportion with altered somatosensory profile, and to analyze demographic characteristics, self-reported function, pain, and health pre- and 3 months post-surgery...
June 17, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28594517/adolescent-spondylolysis-management-and-return-to-play
#10
William C Warner, Rodrigo Góes Medéa de Mendonça
The most common causes of low back pain in adolescents are spondylolysis and spondylolisthesis. Mechanical factors combined with rapid growth during adolescence place stress on the spine and can result in a stress fracture. Sports that require athletes to repeatedly place the spine in hyperextension may exacerbate both spondylolysis and spondylolisthesis. Many adolescent athletes with spondylolysis or low-grade spondylolisthesis have minimal symptoms and require no treatment or alteration in activity, including sports activity...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28594516/lumbar-spine-injuries-in-the-athlete
#11
Dustin H Massel, Kern Singh
Low back pain is the most common complaint expressed by adult patients in the primary care setting, and the incidence of low back pain in adolescents is rising. Adolescents who are involved in athletics most commonly suffer from spondylolysis, spondylolisthesis, mechanical low back pain, and herniated disks, whereas adult athletes most commonly suffer from lumbosacral strain and herniated or degenerative disks. Initial nonsurgical management aims to reduce inflammation and noninvasively strengthen damaged tissues...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28527756/radiological-lumbar-stenosis-severity-predicts-worsening-sagittal-malalignment-on-full-body-standing-stereoradiographs
#12
Aaron J Buckland, Subaraman Ramchandran, Louis Day, Shay Bess, Themistocles Protopsaltis, Peter G Passias, Bassel G Diebo, Renaud Lafage, Virginie Lafage, Akhila Sure, Thomas J Errico
BACKGROUND CONTEXT: Patients with degenerative lumbar stenosis (DLS) adopt a forward flexed posture in an attempt to decompress neural elements. The relationship between sagittal alignment and severity of lumbar stenosis has not previously been studied. PURPOSE: We hypothesized that patients with increasing radiological severity of lumbar stenosis will exhibit worsening sagittal alignment. STUDY DESIGN: This is a cross-sectional study. PATIENT SAMPLE: Our sample consists of patients who have DLS...
May 17, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28506227/associations-between-disc-space-narrowing-anterior-osteophytes-and-disability-in-chronic-mechanical-low-back-pain-a-cross-sectional-study
#13
Romain Shanil Perera, Poruwalage Harsha Dissanayake, Upul Senarath, Lalith Sirimevan Wijayaratne, Aranjan Lional Karunanayake, Vajira Harshadeva Weerabaddana Dissanayake
BACKGROUND: Radiographic features of lumbar disc degeneration (LDD) are common findings in patients with chronic mechanical low back pain; however, its role in disability and intensity of pain is debatable. This study aims to investigate the associations of the x-ray features of LDD and lumbar spondylolisthesis with severity of disability and intensity of pain. METHODS: A cross-sectional study was conducted on 439 patients with chronic mechanical low back pain who attended the rheumatology clinic, National Hospital of Sri Lanka, Colombo, from May 2012 to May 2014...
May 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28435923/bone-bridge-formation-across-the-neuroforamen-14-years-after-instrumented-fusion-for-isthmic-spondylolisthesis-a-case-report
#14
Joel Louis Lim, Kimberly-Anne Tan, Hwee Weng Dennis Hey
This case report describes the first case of a bone bridge formation across the left L5/S1 neuroforamen after instrumented posterolateral fusion for L5/S1 isthmic spondylolisthesis. Our patient was a 70-year-old lady who had grade 2, L5/S1 isthmic spondylolisthesis and bilateral S1 nerve root compression. She suffered from mechanical low back pain and neurogenic claudication, with radicular pain over both S1 dermatomes. She underwent in-situ, instrumented, posterolateral fusion and was asymptomatic for more than 13 years before developing progressive onset of left radicular pain over the L5 dermatome...
March 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28368984/degenerative-spondylolisthesis-is-related-to-multiparity-and-hysterectomies-in-older-women
#15
Jacek Cholewicki, Angela S Lee, John M Popovich, Lawrence W Mysliwiec, Michael D Winkelpleck, John N Flood, Pramod K Pathak, Kiilani H Kaaikala, N Peter Reeves, Ralph Kothe
STUDY DESIGN: A case-control study. OBJECTIVE: To determine whether parity and abdominal surgeries are associated with degenerative spondylolisthesis (DS). SUMMARY OF BACKGROUND DATA: DS is considered to be a major cause of low back pain (LBP) in the older population, with greater prevalence of DS among women. Because LBP and impaired abdominal muscle function are common during pregnancy and post-partum, parity-related abdominal muscle deficiency, resulting in poor spinal mechanics, could be a factor in the development of DS in women...
November 1, 2017: Spine
https://www.readbyqxmd.com/read/28358974/the-impact-of-lumbar-spine-disease-and-deformity-on-total-hip-arthroplasty-outcomes
#16
Daniel J Blizzard, Charles Z Sheets, Thorsten M Seyler, Colin T Penrose, Mitchell R Klement, Michael A Gallizzi, Christopher R Brown
Concomitant spine and hip disease in patients undergoing total hip arthroplasty (THA) presents a management challenge. Degenerative lumbar spine conditions are known to decrease lumbar lordosis and limit lumbar flexion and extension, leading to altered pelvic mechanics and increased demand for hip motion. In this study, the effect of lumbar spine disease on complications after primary THA was assessed. The Medicare database was searched from 2005 to 2012 using International Classification of Diseases, Ninth Revision, procedure codes for primary THA and diagnosis codes for preoperative diagnoses of lumbosacral spondylosis, lumbar disk herniation, acquired spondylolisthesis, and degenerative disk disease...
May 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/28338454/impact-of-preoperative-diagnosis-on-patient-satisfaction-following-lumbar-spine-surgery
#17
MULTICENTER STUDY
Charles H Crawford, Leah Y Carreon, Mohamad Bydon, Anthony L Asher, Steven D Glassman
OBJECTIVE Patient satisfaction is a commonly used metric in the current health care environment. While factors that affect patient satisfaction following spine surgery are complex, the authors of this study hypothesized that specific diagnostic groups of patients are more likely to be satisfied after spine surgery and that this is reflected in patient-reported outcome measures. The purpose of this study was to determine if the preoperative diagnosis-disc herniation, stenosis, spondylolisthesis, adjacent segment degeneration, or mechanical disc collapse-would impact patient satisfaction following surgery...
June 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28250641/traumatic-high-grade-spondylolisthesis-at-c7-t1-with-no-neurological-deficits-case-series-literature-review-and-biomechanical-implications
#18
Ha Son Nguyen, Hesham Soliman, Shekar Kurpad
Traumatic high-grade spondylolisthesis in subaxial cervical spine is frequently associated with acute spinal cord injury and quadriparesis. There have been rare cases where such pathology demonstrates minimal to no neurological deficits. Assessment of the underlying biomechanics may provide insight into the mechanism of injury and associated neurological preservation. Patient 1 is a 63-year-old female presenting after a motor vehicle collision with significant right arm pain without neurological deficits. Imaging demonstrated C7/T1 spondyloptosis, associated with a locked facet on the left at C6/7 and a locked facet on the right at C7/T1, with a fracture of the left C7 pedicle and right C7 lamina...
January 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/28249826/endoscopic-surgical-treatment-of-lumbar-synovial-cyst-detailed-account-of-surgical-technique-and-report-of-11-consecutive-patients
#19
Joachim M Oertel, Benedikt W Burkhardt
BACKGROUND: Lumbar synovial cysts (LSCs) are an uncommon cause of radiculopathy and back pain. Open surgical treatment is associated with extensive bone resection and muscle trauma. The endoscopic tubular-assisted LSC resection has not been described in detail. Here the authors assessed the effectiveness of this technique for LSC resection. METHODS: Eleven patients (4 female and 7 male patients) were operated on via an ipsilateral approach for resection of LSC using an endoscopic tubular retractor system...
July 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28245271/association-between-vertebral-cross-sectional-area-and-lumbar-lordosis-angle-in-adolescents
#20
Tishya A L Wren, Patricia C Aggabao, Ervin Poorghasamians, Thomas A Chavez, Skorn Ponrartana, Vicente Gilsanz
Lumbar lordosis (LL) is more prominent in women than in men, but the mechanisms responsible for this discrepancy are poorly defined. A recent study indicates that newborn girls have smaller vertebral cross-sectional area (CSA) when compared to boys-a difference that persists throughout life and is independent of body size. We determined the relations between vertebral cross-sectional area (CSA) and LL angle and whether sex differences in lumbar lordosis are related to sex differences in vertebral CSA. Using multi-planar magnetic resonance imaging (MRI), we measured vertebral cross-sectional area (CSA) and vertebral height of the spine of 40 healthy boys and 40 girls, ages 9-13 years...
2017: PloS One
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