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https://www.readbyqxmd.com/read/29913462/curriculum-development-and-implementation-of-a-national-interprofessional-fellowship-in-patient-safety
#1
Bradley V Watts, Linda Williams, Peter D Mills, Douglas E Paull, Jeffrey A Cully, Stuart C Gilman, Robin R Hemphill
OBJECTIVES: Developing a workforce skilled in improving the safety of medical care has often been cited as an important means to achieve safer care. Although some educational programs geared toward patient safety have been developed, few advanced training programs have been described in the literature. We describe the development of a patient safety fellowship program. METHODS: We describe the development and curriculum of an Interprofessional Fellowship in Patient Safety...
June 15, 2018: Journal of Patient Safety
https://www.readbyqxmd.com/read/29913348/from-linear-care-plan-through-concept-map-to-concepto-plan-the-creation-of-an-innovative-and-holistic-care-plan
#2
M Sherry McDonald, Melanie Neumeier, Mark E Olver
Linear care plans have traditionally been used in nursing education to support nursing students in identifying potential and actual health care problems, and to follow up on those issues with nursing interventions. However, the linear care plan does not support the nursing student with learning in-depth critical thinking, clinical reasoning, creative thinking, and other ways of thinking. Concept mapping was introduced as a way to support the nursing student to improve upon critical thinking and clinical reasoning and to identify relationships among the patient's health care problems...
May 26, 2018: Nurse Education in Practice
https://www.readbyqxmd.com/read/29913317/evaluation-of-knowledge-regarding-gestational-diabetes-mellitus-a-bangladeshi-study
#3
B Bhowmik, F Afsana, T Ahmed, T Siddiquee, T Ahmed, F Pathan, H Mahtab, A K A Khan
OBJECTIVE: The aim of this study was to evaluate the level of knowledge about gestational diabetes mellitus (GDM) in Bangladeshi people. STUDY DESIGN: Cross-sectional study. METHODS: This study involving 1374 participants was conducted in 15 outpatient clinics of Diabetic Association of Bangladesh and its affiliated associations, Bangabandhu Sheikh Mujib Medical University and four medical college hospitals in Bangladesh from August 2015 to December 2015...
June 15, 2018: Public Health
https://www.readbyqxmd.com/read/29912882/young-children-fail-to-generate-an-additive-ratchet-effect-in-an-open-ended-construction-task
#4
Eva Reindl, Claudio Tennie
The ratchet effect-the gradual accumulation of changes within a cultural trait beyond a level that individuals can achieve on their own-arguably rests on two key cognitive abilities: high-fidelity social learning and innovation. Researchers have started to simulate the ratchet effect in the laboratory to identify its underlying social learning mechanisms, but studies on the developmental origins of the ratchet effect remain sparse. We used the transmission chain method and a tower construction task that had previously been used with adults to investigate whether "generations" of children between 4 and 6 years were able to make a technological product that individual children could not yet achieve...
2018: PloS One
https://www.readbyqxmd.com/read/29912815/monitoring-self-reported-adherence-to-antiretroviral-therapy-in-public-hiv-care-facilities-in-brazil-a-national-cross-sectional-study
#5
Maria Altenfelder Santos, Mark Drew Crosland Guimarães, Ernani Tiaraju Santa Helena, Cáritas Relva Basso, Felipe Campos Vale, Wania Maria do Espírito Santo Carvalho, Ana Maroso Alves, Gustavo Machado Rocha, Francisco de Assis Acurcio, Maria das Graças Braga Ceccato, Rogério Ruscitto do Prado, Paulo Rossi Menezes, Maria Ines Batistella Nemes
INTRODUCTION: Patient adherence to antiretroviral therapy (ART) is critical for HIV treatment success. Monitoring rates of adherence in public HIV outpatient care facilities can improve outcomes in Brazil where ART is universally available. METHODS: We conducted a national cross-sectional survey of ART adherence in 2010. Participants were selected using a multistage probability sample. First, HIV outpatient care facilities were stratified according to 7 Organizational Quality Classification (OQC) groups and regions...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29911964/potentially-preventable-hospital-and-emergency-department-events-lessons-from-a-large-innovation-project
#6
Leif I Solberg, Kris A Ohnsorg, Emily D Parker, Robert Ferguson, Sanne Magnan, Robin R Whitebird, Claire Neely, Emily Brandenfels, Mark D Williams, Mark Dreskin, Todd Hinnenkamp, Jeanette Y Ziegenfuss
INTRODUCTION: There are few proven strategies to reduce the frequency of potentially preventable hospitalizations and Emergency Department (ED) visits. To facilitate strategy development, we documented these events among complex patients and the factors that contribute to them in a large care-improvement initiative. METHODS: Observational study with retrospective audits and selective interviews by the patients' care managers among 12 diverse medical groups in California, Minnesota, Pennsylvania, and Washington that participated in an initiative to implement collaborative care for patients with both depression and either uncontrolled diabetes, uncontrolled hypertension, or both...
June 4, 2018: Permanente Journal
https://www.readbyqxmd.com/read/29911919/innovative-treatment-for-pes-cavovarus-a-pilot-study-of-13-children
#7
Ignacio Sanpera, Guillem Frontera-Juan, Julia Sanpera-Iglesias, Laura Corominas-Frances
Background and purpose - Pes cavovarus (PCV) is a complex deformity, frequently related to neurological conditions and associated with foot pain, callosities, and walking instability. The deformity has the tendency to increase during growth. Orthotic treatment is ineffective and surgery may be troublesome. We present the preliminary results of a new mini-invasive surgical technique for correction of this foot deformity. Patients and methods - We operated on 13 children (24 feet), age 7-13 years. In 7 children the deformity was neurological in origin...
June 18, 2018: Acta Orthopaedica
https://www.readbyqxmd.com/read/29911856/full-spectrum-isotopic-13c-nmr-using-polarization-transfer-for-position-specific-isotope-analysis
#8
Valentin Joubert, Virginie Silvestre, Mathilde Grand, Denis Loquet, Virginie Ladroue, Fabrice Besacier, Serge Akoka, Gerald Stanislas Remaud
For the last ten years, quantitative isotope ratio monitoring 13C NMR (irm-13C NMR) has been successfully tested and proved as an efficient tool for the determination of the position-specific determination of 13C/12C ratios. Several applications in different domains have shown its interest. In the context of origin assignment, the possibility to track the distribution network of illicit drugs or cutting agents is of prime importance. However irm-13C NMR still suffers from a relative lack of sensitivity limiting its dissemination among control laboratories...
June 18, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29911603/experimental-design-and-reporting-standards-for-improving-the-internal-validity-of-pre-clinical-studies-in-the-field-of-pain-consensus-of-the-imi-europain-consortium
#9
K L Knopp, C Stenfors, C Baastrup, A W Bannon, M Calvo, O Caspani, G Currie, N B Finnerup, W Huang, J D Kennedy, I Lefevre, I Machin, M Macleod, H Rees, A S C Rice, K Rutten, M Segerdahl, J Serra, R Wodarski, O-G Berge, R-D Treedef
Background and aims Pain is a subjective experience, and as such, pre-clinical models of human pain are highly simplified representations of clinical features. These models are nevertheless critical for the delivery of novel analgesics for human pain, providing pharmacodynamic measurements of activity and, where possible, on-target confirmation of that activity. It has, however, been suggested that at least 50% of all pre-clinical data, independent of discipline, cannot be replicated. Additionally, the paucity of "negative" data in the public domain indicates a publication bias, and significantly impacts the interpretation of failed attempts to replicate published findings...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29911135/a-novel-suture-button-construct-for-acute-ankle-syndesmotic-injuries-a-prospective-clinical-and-radiological-analysis
#10
Mohamed A Imam, James Holton, Abdel Na Hassan, Ahmed Matthana
Background: The importance of the syndesmosis in ankle stability is well recognized. Numerous means of fixation have been described for syndesmotic injuries including the suture button technique. Significant cost limits the use the commercially available options. We, therefore, designed a cheap and readily available alternative construct. We aim to assess the results of using a novel suture-button construct in treatment of syndesmotic ankle injuries. Methods: Fifty-two patients (34 males and 18 females) fulfilled our inclusion/exclusion criteria...
May 2018: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29910640/gaming-science-innovations-to-integrate-health-systems-science-into-medical-education-and-practice
#11
REVIEW
Earla J White, Joy H Lewis, Lise McCoy
Health systems science (HSS) is an emerging discipline addressing multiple, complex, interdependent variables that affect providers' abilities to deliver patient care and influence population health. New perspectives and innovations are required as physician leaders and medical educators strive to accelerate changes in medical education and practice to meet the needs of evolving populations and systems. The purpose of this paper is to introduce gaming science as a lens to magnify HSS integration opportunities in the scope of medical education and practice...
2018: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/29910128/miming-neurological-syndromes-improves-medical-student-s-long-term-retention-and-delayed-recall-of-neurology
#12
Emmanuel Roze, Yulia Worbe, Céline Louapre, Aurélie Méneret, Cécile Delorme, Eavan McGovern, Marta Ruiz, Jean Capron, Raphaël Le Bouc, Stéphane Epelbaum, Sonia Alamowitch, Alexandre Duguet, Marie-Christine Renaud, Olivier Palombi, Tamara M Pringsheim, Constance Flamand-Roze, Olivier Steichen
Basic examination and diagnostic skills in neurology are important for every graduating medical student. However, a majority of medical students consider neurology as complex and difficult to master. We evaluate the impact a learner-friendly, innovative simulation-based training programme has on long-term retention and delayed recall of neurological semiology amongst third-year medical students from the University Pierre et Marie Curie in Paris, France. The 2013 class received standard teaching in neurological semiology...
June 7, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29909912/pre-clinical-development-of-chimeric-antigen-receptor-t-cell-immunotherapy-implications-of-design-for-efficacy-and-safety
#13
REVIEW
Leena Halim, Adam Ajina, John Maher
Following the landmark approvals by the United States Food and Drug Administration, the adoptive transfer of CD19-directed chimeric antigen receptor (CAR) T-cells has now entered mainstream clinical practice for patients with chemotherapy-resistant or refractory B-cell malignancies. These approvals have followed on from a prolonged period of pre-clinical evaluation, informing the design of clinical trials that have demonstrated unprecedented efficacy in this difficult to treat patient population. However, the delivery of autologous CAR-engineered T-cell therapy is complex, costly and not without significant risk...
June 2018: Best Practice & Research. Clinical Haematology
https://www.readbyqxmd.com/read/29909876/building-synergy-between-regulatory-and-hta-agencies-beyond-processes-and-procedures-can-we-effectively-align-the-evidentiary-requirements-a-survey-of-stakeholder-perceptions
#14
Ting Wang, Neil McAuslane, Lawrence Liberti, Hubert Leufkens, Anke Hövels
OBJECTIVES: To evaluate the current practice of companies and agencies to assess the changes made in aligning regulatory and health technology assessment (HTA) stakeholders; to identify areas of commonality of evidentiary requirements that could occur; and to identify strategic issues and trends of regulatory and HTA synergy. METHODS: Two separate questionnaires were developed to assess stakeholders' perceptions on regulatory and HTA alignment, one for pharmaceutical companies and the other for regulatory and HTA agencies...
June 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29909431/enhancing-early-childhood-mental-health-primary-care-services-evaluation-of-ma-project-launch
#15
Beth E Molnar, Kristin E Lees, Kate Roper, Natasha Byars, Larisa Méndez-Peñate, Christy Moulin, William McMullen, Jessica Wolfe, Deborah Allen
Objectives The purpose of this study was to evaluate the efficacy of an innovative early childhood mental health intervention, Massachusetts Project LAUNCH. Early childhood mental health clinicians and family partners (paraprofessionals with lived experience) were embedded within community pediatric medical homes. Methods A longitudinal study design was used to test the hypotheses that (1) children who received services would experience decreased social, emotional and behavioral problems over time and (2) caregivers' stress and depressive symptoms would decrease over time...
June 16, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29909284/lean-methodology-in-healthcare
#16
REVIEW
Rubin I Cohen
To improve the delivery of patient care, governments and healthcare institutions adopted quality improvement methods that had been developed decades earlier in manufacturing industries. Many healthcare practitioners are either unaware or are inexperienced about what these practices entail and whether they are successful in healthcare. This article reviews Lean, an improvement philosophy made famous by the Toyota Motor Company. Lean uses a set of instruments and incorporates a long-term vision aiming for continuous improvement...
June 14, 2018: Chest
https://www.readbyqxmd.com/read/29908022/relationship-between-lean-practices-soft-total-quality-management-and-innovation-skills-in-lebanese-hospitals
#17
Malak Aoun, Norlena Hasnan, Hassan Al-Aaraj
Background: Lean practices are critical to eliminate waste and enhance the quality of healthcare services through different improvement approaches of total quality management (TQM). In particular, the soft side of TQM is used to develop the innovation skills of employees that are essential for the continuous improvement strategies of hospitals. Aim: The main objective was to study the relationship between lean practices, soft TQM and innovation skills in Lebanese hospitals...
June 10, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29907511/developing-and-assessing-electronic-checklists-for-safety-mindfulness-workload-and-performance
#18
Gregg S Tracton, Lukasz M Mazur, Prithima Mosaly, Lawrence B Marks, Shiva Das
PURPOSE: The aim of this study is to propose a set of innovative principles for the effective design of electronic checklists to enhance safety mindfulness (a specific safety mindful mindset that offers the opportunity to operate more preemptively during routine quality assurance tasks) and discuss some of our preliminary results from testing our proposed electronic checklist with dosimetrists and physicists. METHODS AND MATERIALS: A multidisciplinary team designed, developed, and evaluated the utility of the electronic checklist (vs paper-based checklist) to promote safety mindfulness...
May 16, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29907502/functional-liver-image-guided-hepatic-therapy-flight-with-hepatobiliary-iminodiacetic-acid-hida-scans
#19
David E Long, Mark Tann, Ke Colin Huang, Gregory Bartlett, James O Galle, Yukie Furukawa, Mary Maluccio, John A Cox, Feng-Ming Spring Kong, Susannah G Ellsworth
PURPOSE: Hepatobiliary iminodiacetic acid (HIDA) scans provide global and regional assessments of liver function that can serve as a road map for functional avoidance in stereotactic body radiation therapy (SBRT) planning. Functional liver image guided hepatic therapy (FLIGHT), an innovative planning technique, is described and compared with standard planning using functional dose-volume histograms. Thresholds predicting for decompensation during follow up are evaluated. METHODS AND MATERIALS: We studied 17 patients who underwent HIDA scans before SBRT...
May 1, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29907306/from-plant-metabolic-engineering-to-plant-synthetic-biology-the-evolution-of-the-design-build-test-learn-cycle
#20
REVIEW
Benjamin Pouvreau, Thomas Vanhercke, Surinder Singh
Genetic improvement of crops started since the dawn of agriculture and has continuously evolved in parallel with emerging technological innovations. The use of genome engineering in crop improvement has already revolutionised modern agriculture in less than thirty years. Plant metabolic engineering is still at a development stage and faces several challenges, in particular with the time necessary to develop plant based solutions to bio-industrial demands. However the recent success of several metabolic engineering approaches applied to major crops are encouraging and the emerging field of plant synthetic biology offers new opportunities...
August 2018: Plant Science: An International Journal of Experimental Plant Biology
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