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Innovation improvement

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https://www.readbyqxmd.com/read/29679033/innovatively-therapeutic-strategy-on-lung-cancer-by-daily-drinking-antioxidative-plasmon-induced-activated-water
#1
Chien-Kai Wang, Hsiao-Chien Chen, Sheng-Uei Fang, Chia-Wen Ho, Cheng-Jeng Tai, Chih-Ping Yang, Yu-Chuan Liu
Many human diseases are inflammation-related, such as cancer and those associated with aging. Previous studies demonstrated that plasmon-induced activated (PIA) water with electron-doping character, created from hot electron transfer via decay of excited Au nanoparticles (NPs) under resonant illumination, owns reduced hydrogen-bonded networks and physchemically antioxidative properties. In this study, it is demonstrated PIA water dramatically induced a major antioxidative Nrf2 gene in human gingival fibroblasts which further confirms its cellular antioxidative and anti-inflammatory properties...
April 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29678912/characterizing-the-ecology-of-vibrio-in-the-neuse-river-estuary-north-carolina-using-heat-shock-protein-60-hsp60-next-generation-amplicon-sequencing
#2
Kelsey J Jesser, Rachel T Noble
Of marine eubacteria, the genus Vibrio is intriguing because member species are relevant to both marine ecology and human health. Many have touted the relationships of Vibrio to environmental factors, especially temperature and salinity, to predict total Vibrio abundance, but these studies lacked the taxonomic resolution to identify relationships among species and key drivers of Vibrio dynamics. In order to improve NGS surveys of Vibrio, we have conducted both 16S small subunit ribosomal RNA (rRNA) and heat shock protein 60 ( hsp60 ) amplicon sequencing of water samples collected at two well-studied locations in the Neuse River Estuary, NC...
April 20, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29678806/a-novel-algorithm-for-determining-the-contextual-characteristics-of-movement-behaviors-by-combining-accelerometer-features-and-wireless-beacons-development-and-implementation
#3
Daniele Magistro, Salvatore Sessa, Andrew P Kingsnorth, Adam Loveday, Alessandro Simeone, Massimiliano Zecca, Dale W Esliger
BACKGROUND: Unfortunately, global efforts to promote "how much" physical activity people should be undertaking have been largely unsuccessful. Given the difficulty of achieving a sustained lifestyle behavior change, many scientists are reexamining their approaches. One such approach is to focus on understanding the context of the lifestyle behavior (ie, where, when, and with whom) with a view to identifying promising intervention targets. OBJECTIVE: The aim of this study was to develop and implement an innovative algorithm to determine "where" physical activity occurs using proximity sensors coupled with a widely used physical activity monitor...
April 20, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29678606/ketogenic-diet-high-intensity-interval-training-hiit-and-memory-training-in-the-treatment-of-mild-cognitive-impairment-a-case-study
#4
Kaitlyn Dahlgren, Kelly J Gibas
Alzheimer's disease (AD) deaths have increased by 89% since 2000. This alarming trajectory of neurological disease highlights the failure of current best practice. Deteriorating brain fuel supply is the nemesis of intact neurological health. Cerebral hypo-metabolism associated with AD occurs years before onset. Both the ketogenic diet and calorie restriction (fasting) lead to a compensatory rise in ketones to improve energy deficits in the brain derived from cerebral insulin resistance. Two forms of ketone bodies, β-hydroxybutyrate and acetoacetate, fuel the brain during starvation, fasting and strenuous exercise...
April 11, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29678137/supporting-teams-to-optimize-function-and-independence-in-veterans-a-multi-study-program-and-mixed-methods-protocol
#5
Virginia Wang, Kelli Allen, Courtney H Van Houtven, Cynthia Coffman, Nina Sperber, Elizabeth P Mahanna, Cathleen Colón-Emeric, Helen Hoenig, George L Jackson, Teresa M Damush, Erika Price, Susan N Hastings
BACKGROUND: Successful implementation of new clinical programs depends on effectively establishing, reorganizing, or enhancing team structures and processes to coordinate the work of individuals who are interdependent in their tasks, manage relationships, and share responsibility for outcomes. However, a one-size-fits-all approach is rarely effective. In partnership with VA national clinical leaders and local clinical champions, the Optimizing Function and Independence VA Quality Enhancement Research Initiative program (Function QUERI) will evaluate efforts to implement team-based clinical programs for Veterans at risk for functional decline and disability...
April 20, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29678071/ready-for-hit-innovations-developing-a-tool-to-assess-the-professionalism-of-information-management-in-hospitals
#6
Jan-David Liebe, Moritz Esdar, Franziska Jahn, Ursula Hübner
Current frameworks postulate the success of health IT innovations to be determined by the professionalism of the information management (PIM). Still, empirical knowledge about PIM is scarce up until today. This study seeks to answer three research questions: (1.) How can PIM be measured in a reliable and valid way, (2.) how pronounced is PIM in German hospitals and (3.) do hospital characteristics have an impact on the degree of PIM? Based on the results of an expert workshop and frameworks for information management (IM) items for a PIM inventory were developed and the inventory sent to 1349 chief information officers of German hospitals...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677989/paflochar-an-innovating-approach-to-characterise-patient-flows-in-myocardial-infarction
#7
Jessica Pinaire, Jérôme Azé, Sandra Bringay, Pascal Poncelet, Christophe Genolini, Paul Landais
A better knowledge of patient flows would improve decision making in health planning. In this article, we propose a method to characterise patients flows and also to highlight profiles of care pathways considering times and costs. From medico-administrative data, we extracted spatio-temporal patterns. Then, we clustered time between hospitalisations and cost trajectories in order to identify profiles of change over time. This approach may support renewed management strategies.
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677959/ehealth-platforms-the-case-of-europe
#8
Martin Benedict, Hanno Herrmann, Werner Esswein
Platform approaches to improve interorganisational integration and eHealth innovation have gained a lot of attention. A variety of platform projects have been established in Europe. However, a systematic view is missing. Based on a multiple source analysis, this paper collects existing European eHealth-platforms and systematizes them with regard to their functional adjustment. We contribute by proving a functional cluster of platforms. The paper describes classification dimensions and identifies two general classes of platforms in the healthcare sector...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677381/technology-innovations-for-better-fall-risk-management-in-home-care
#9
Güneş Koru, Dari Alhuwail, Onimi Jademi, Uchenna Uchidiuno, Robert J Rosati
Achieving better fall risk management is an integral component of quality home care. The current qualitative study uncovers the challenges and opportunities of home health agencies (HHAs) in achieving better fall risk management. A secondary document analysis was adopted to learn from rich contextual information in fall incident reports recorded in a HHA. Poor engagement of patients and caregivers was a contributing factor in many fall incidents. Patients often fell as a result of not understanding or accepting their physical limitations...
April 19, 2018: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/29677046/student-and-preceptor-advancement-in-a-dedicated-education-site-innovation-in-clinical-education-for-advanced-practice-nurses
#10
Katherine C Hall, Sandy K Diffenderfer, April Stidham, Christine M Mullins
In the 1990s, dedicated education units transformed undergraduate preceptorships, but graduate preceptorships remain static. The dyadic nurse practitioner preceptorship model supports an environment where faculty, students, and preceptors may overlook nuances that affect the teaching-learning process. This article describes an innovative clinical education model, Student and Preceptor Advancement in a Dedicated Education Site, designed to improve preceptorships for advanced practice nurses. The focus is on adaptations made to facilitate use in advanced practice nursing programs...
April 19, 2018: Nursing Education Perspectives
https://www.readbyqxmd.com/read/29676249/preharvest-farming-practices-impacting-fresh-produce-safety
#11
Eduardo Gutierrez-Rodriguez, Achyut Adhikari
Advancements in agriculture and food processing techniques have been instrumental in the development of modern human societies. Vast improvements in agronomic practices, handling, and processing have allowed us to produce and preserve mass quantities of food. Yet despite all these innovations and potentially as a consequence of these mass production practices, more and more outbreaks of human pathogens linked to raw and processed foods are identified every year. It is evident that our increased capacity for microbial detection has contributed to the greater number of outbreaks detected...
April 2018: Microbiology Spectrum
https://www.readbyqxmd.com/read/29675545/a-novel-approach-to-improving-ambulatory-outpatient-management-of-low-risk-febrile-neutropenia-an-enhanced-supportive-care-esc-clinic
#12
Tim Cooksley, Geraldine Campbell, Tamer Al-Sayed, Lisa LaMola, Richard Berman
PURPOSE: Outpatient management of low risk febrile neutropenia patients (LRFN) identified by the MASCC score is a safe and effective strategy. Early supportive care has been shown to improve outcomes in patients with care. We developed an innovative ambulatory outpatient "enhanced supportive care" (ESC) clinic combining emergency oncology and supportive care through which we incorporated the management of patients with LRFN. METHODS: An ESC clinic was started in January 2017 at a tertiary cancer hospital in the North West of England...
April 19, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29675269/translation-of-remote-control-regenerative-technologies-for-bone-repair
#13
Hareklea Markides, Jane S McLaren, Neil D Telling, Noura Alom, E'atelaf A Al-Mutheffer, Richard O C Oreffo, Andrew Zannettino, Brigitte E Scammell, Lisa J White, Alicia J El Haj
The role of biomechanical stimuli, or mechanotransduction, in normal bone homeostasis and repair is understood to facilitate effective osteogenesis of mesenchymal stem cells (MSCs) in vitro. Mechanotransduction has been integrated into a multitude of in vitro bone tissue engineering strategies and provides an effective means of controlling cell behaviour towards therapeutic outcomes. However, the delivery of mechanical stimuli to exogenous MSC populations, post implantation, poses a significant translational hurdle...
2018: NPJ Regenerative Medicine
https://www.readbyqxmd.com/read/29674362/implementation-of-an-evidence-based-model-of-care-for-low-back-pain-in-emergency-departments-protocol-for-the-sydney-health-partners-emergency-department-shaped-trial
#14
Gustavo C Machado, Bethan Richards, Chris Needs, Rachelle Buchbinder, Ian A Harris, Kirsten Howard, Kirsten McCaffery, Laurent Billot, James Edwards, Eileen Rogan, Rochelle Facer, David Lord Cowell, Chris G Maher
INTRODUCTION: Patients with low back pain often seek care in emergency departments, but the problem is that many patients receive unnecessary or ineffective interventions and at the same time miss out on the basics of care, such as advice on self-management. This pattern of care has important consequences for the healthcare system (expensive and inefficient) and for patients (poor health outcomes). We hypothesised that the implementation of an evidence-based model of care for low back pain will improve emergency care by reducing inappropriate overuse of tests and treatments and improving patient outcomes...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29674346/from-microscopic-to-macroscopic-sports-injuries-applying-the-complex-dynamic-systems-approach-to-sports-medicine-a-narrative-review
#15
REVIEW
Rafel Pol, Robert Hristovski, Daniel Medina, Natalia Balague
A better understanding of how sports injuries occur in order to improve their prevention is needed for medical, economic, scientific and sports success reasons. This narrative review aims to explain the mechanisms that underlie the occurrence of sports injuries, and an innovative approach for their prevention on the basis of complex dynamic systems approach. First, we explain the multilevel organisation of living systems and how function of the musculoskeletal system may be impaired. Second, we use both, a constraints approach and a connectivity hypothesis to explain why and how the susceptibility to sports injuries may suddenly increase...
April 19, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29674229/analytical-reverse-time-migration-an-innovation-in-imaging-of-infrastructures-using-ultrasonic-shear-waves
#16
Aziz Asadollahi, Lev Khazanovich
The emergence of ultrasonic dry point contact (DPC) transducers that emit horizontal shear waves has enabled efficient collection of high-quality data in the context of a nondestructive evaluation of concrete structures. This offers an opportunity to improve the quality of evaluation by adapting advanced imaging techniques. Reverse time migration (RTM) is a simulation-based reconstruction technique that offers advantages over conventional methods, such as the synthetic aperture focusing technique. RTM is capable of imaging boundaries and interfaces with steep slopes and the bottom boundaries of inclusions and defects...
April 11, 2018: Ultrasonics
https://www.readbyqxmd.com/read/29674109/mixed-method-evaluation-of-a-cadaver-dissection-course-for-general-surgery-interns-an-innovative-approach-for-filling-the-gap-between-gross-anatomy-and-the-operating-room
#17
Yen-Yi Juo, Christina Hanna, Quach Chi, Grace Chang, Warwick J Peacock, Areti Tillou, Catherine E Lewis
OBJECTIVE: To evaluate an innovative whole cadaver dissection curriculum designed to focus on teaching procedure-relevant anatomy and surgical skills to surgery interns. DESIGN: A mixed methods explanatory sequential design incorporating both quantitative and qualitative evaluations was used to evaluate the cadaver dissection course. Quantitative data were prospectively collected and retrospectively reviewed in order to compare anatomy knowledge and operative skills before and after the course...
April 16, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29674012/interventional-radiology-operated-endoscopy-as-an-adjunct-to-image-guided-interventions
#18
REVIEW
Rajiv N Srinivasa, Jeffrey Forris Beecham Chick, Kyle Cooper, Ravi N Srinivasa
PURPOSE: Interventional radiology-operated endoscopy is an underused technique, which may have a significant impact on the ability to treat patients with a variety of conditions. The purpose of this article is to discuss the setup, equipment, and potential clinical uses of interventional radiology-operated endoscopy. METHODS: A number of new and innovative interventions may be performed in the biliary, genitourinary, and gastrointestinal systems through percutaneous access that interventional radiologists already create...
March 20, 2018: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29673581/hoping-for-more-how-cognitive-science-has-and-hasn-t-been-helpful-to-the-ocd-clinician
#19
REVIEW
Allison J Ouimet, Andrea R Ashbaugh, Adam S Radomsky
Cognitive-behavioural models of obsessive-compulsive disorder (OCD) stemmed from knowledge acquired from cognitive science. Researchers continue to apply basic cognitive-affective science methods to understanding OCD, with the overarching goal of improving and refining evidence-based treatments. However, the degree to which such research has contributed to this goal is unclear. We reviewed OCD research in the general areas that comprise basic cognitive science, and evaluated the degree to which it has contributed to our understanding of the development, maintenance, and treatment of OCD...
April 12, 2018: Clinical Psychology Review
https://www.readbyqxmd.com/read/29673231/mapping-european-welfare-models-state-of-the-art-of-strategies-for-professional-integration-and-reintegration-of-persons-with-chronic-diseases
#20
Chiara Scaratti, Matilde Leonardi, Fabiola Silvaggi, Carolina C Ávila, Amalia Muñoz-Murillo, Panayiota Stavroussi, Olga Roka, Helena Burger, Klemens Fheodoroff, Beata Tobiasz-Adamczyk, Carla Sabariego, Eva Esteban, Sonja Gruber, Olga Svestkova, Rune Halvorsen, Asel Kadyrbaeva, Sabrina Ferraina
Background: Persons with chronic diseases (PwCDs) often experience work-related problems, and innovative actions to improve their participation in the labor market are needed. In the frame of the European (EU) Pathways Project, the aim of the study is to compare existing strategies (policies, systems, and services) for professional (re-)integration of PwCDs and mental health conditions available at both European and national level between different European welfare models: Scandinavian, Continental, Anglo-Saxon, Mediterranean, and “Post-Communist”...
April 17, 2018: International Journal of Environmental Research and Public Health
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