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https://www.readbyqxmd.com/read/28208819/the-comparative-reliability-and-feasibility-of-the-past-year-canadian-diet-history-questionnaire-ii-comparison-of-the-paper-and-web-versions
#1
Geraldine Lo Siou, Ilona Csizmadi, Beatrice A Boucher, Alianu K Akawung, Heather K Whelan, Michelle Sharma, Ala Al Rajabi, Jennifer E Vena, Sharon I Kirkpatrick, Anita Koushik, Isabelle Massarelli, Isabelle Rondeau, Paula J Robson
Advances in technology-enabled dietary assessment include the advent of web-based food frequency questionnaires, which may reduce costs and researcher burden but may introduce new challenges related to internet connectivity and computer literacy. The purpose of this study was to evaluate the intra- and inter-version reliability, feasibility and acceptability of the paper and web Canadian Diet History Questionnaire II (CDHQ-II) in a sub-sample of 648 adults (aged 39-81 years) recruited from Alberta's Tomorrow Project...
February 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28199930/prevalence-of-exposure-to-suicide-a-meta-analysis-of-population-based-studies
#2
Karl Andriessen, Bayzidur Rahman, Brian Draper, Michael Dudley, Philip B Mitchell
Those exposed to suicide are at increased risk of adverse outcomes including mental illness, impaired social functioning, and fatal and non-fatal suicidal behavior. However, it is unclear how many people are exposed to suicide in the general community. This first meta-analysis of population-based studies aimed to provide pooled estimates of past-year and lifetime prevalence of exposure to suicide among family, friends/peers, and all relationships. In addition, the study examined prevalence of exposure to suicide by age group: adolescents and adults...
February 3, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28198041/does-midwife-experience-affect-the-rate-of-severe-perineal-tears
#3
Yossi Mizrachi, Sophia Leytes, Michal Levy, Zvia Hiaev, Shimon Ginath, Jacob Bar, Michal Kovo
BACKGROUND: Our aim was to study whether midwife experience affects the rate of severe perineal tears (3rd and 4th degree). METHODS: A retrospective cohort study of all women with term vertex singleton pregnancies, who underwent normal vaginal deliveries, in a single tertiary hospital, between 2011 and 2015, was performed. Exclusion criteria were instrumental deliveries and stillbirth. All midwives used a "hands on" technique for protecting the perineum. The midwife experience at each delivery was calculated as the time interval between her first delivery and current delivery...
February 15, 2017: Birth
https://www.readbyqxmd.com/read/28197646/an-observational-follow-up-study-on-pelvic-floor-disorders-to-3-5-years-after-delivery
#4
Karen Ng, Rachel Yau Kar Cheung, Lai Loi Lee, Tony Kwok Hung Chung, Symphorosa Shing Chee Chan
INTRODUCTION AND HYPOTHESIS: This study aimed to determine the prevalence of urinary incontinence (UI), fecal incontinence (FI), and pelvic organ prolapse (POP) 3-5 years after the first pregnancy and their associated risk factors. METHODS: We assessed 506 women using the Pelvic Floor Distress Inventory (PFDI) and the Pelvic Floor Impact Questionnaire (PFIQ). Maternal characteristics and obstetric data were analyzed using descriptive analysis, independent sample t test, chi-squared test, and logistic regression...
February 14, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28196115/nutritional-assessment-of-community-dwelling-older-adults-in-rural-nepal
#5
Saruna Ghimire, Binaya Kumar Baral, Karen Callahan
BACKGROUND: Demographic transition in Nepal, like in many developing countries, has resulted in a burgeoning elderly population whose health status is not currently monitored. One pillar of health is adequate nutrition. Yet, little is known about the nutritional health status of the elderly in Nepal. The financial, material, and personnel limitations in Nepal's health delivery services necessitate health screening instruments that require minimal clinical staff and resources. To our knowledge, no such nutritional assessment tool has been validated in Nepal...
2017: PloS One
https://www.readbyqxmd.com/read/28194981/droplet-assisted-inlet-ionization-for-online-analysis-of-airborne-nanoparticles
#6
Andrew J Horan, Michael J Apsokardu, Murray V Johnston
Airborne nanoparticles play a key role in climate effects as well as impacting human health. Their small mass and complex chemical composition represent significant challenges for analysis. This work introduces a new ionization method, droplet assisted inlet ionization (DAII), where aqueous droplets are produced from airborne nanoparticles. When these droplets enter the mass spectrometer through a heated inlet, rapid vaporization leads to the formation of molecular ions. The method is demonstrated with test aerosols consisting of polypropylene glycol (PPG), angiotensin II, bovine serum albumin, and the "thermometer" compound p-methoxybenzylpyridinium chloride...
January 17, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28192678/assaying-the-stability-and-inactivation-of-aav-serotype-1-vectors
#7
Douglas B Howard, Brandon K Harvey
Adeno-associated virus (AAV) vectors are a commonplace tool for gene delivery ranging from cell culture to human gene therapy. One feature that makes AAV a desirable vector is its stability, in regard to both the duration of transgene expression and retention of infectivity as a viral particle. This study examined the stability of AAV serotype 1 (AAV1) vectors under different conditions. First, transducibility after storage at 4°C decreased 20% over 7 weeks. Over 10 freeze-thaw cycles, the resulting transduction efficiency became variable at 60-120% of a single thaw...
February 2017: Human Gene Therapy Methods
https://www.readbyqxmd.com/read/28191626/intermittent-auscultation-ia-of-fetal-heart-rate-in-labour-for-fetal-well-being
#8
REVIEW
Ruth Martis, Ova Emilia, Detty S Nurdiati, Julie Brown
BACKGROUND: The goal of fetal monitoring in labour is the early detection of a hypoxic baby. There are a variety of tools and methods available for intermittent auscultation (IA) of the fetal heart rate (FHR). Low- and middle-income countries usually have only access to a Pinard/Laënnec or the use of a hand-held Doppler device. Currently, there is no robust evidence to guide clinical practice on the most effective IA tool to use, timing intervals and length of listening to the fetal heart for women during established labour...
February 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28183818/normalization-of-hemoglobin-based-oxygen-carrier-201-induced-vasoconstriction-roles-of-nitric-oxide-scavenging-and-endothelin
#9
Yannick J Taverne, Daphne P M de Wijs-Meijler, Maaike Te Lintel Hekkert, Paula F Moon-Massat, Greg P Dubé, Dirk Jan Duncker, Daphne Merkus
BACKGROUND: Hemoglobin-based oxygen carrier (HBOC)-201 is a cell-free modified hemoglobin solution potentially facilitating oxygen uptake and delivery in cardiovascular disorders and hemorrhagic shock. Clinical use has been hampered by vasoconstriction in the systemic and pulmonary beds. Therefore we aimed to 1) determine the possibility of counteracting HBOC-201-induced pressor effects with adenosine (ADO), 2) assess the potential roles of nitric oxide (NO) scavenging, reactive oxygen species (ROS) and endothelin (ET) in mediating the observed vasoconstriction and 3) compare these effects in resting and exercising swine...
February 9, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28179719/a-pharmacy-elective-course-on-creative-thinking-innovation-and-ted-talks
#10
Jeff Cain
Objective. To implement and assess an elective course designed to enhance student creative thinking and presentation skills. Design. A two-credit elective course was developed that incorporated creative-thinking exercises, article discussions pertaining to creativity, TED Talk (TED Conferences, New York, NY) analyses, and presentation design and delivery exercises. Assessment. Assessment instruments included pre- and post-course Torrance Tests of Creative Thinking (TTCT). A scoring rubric was developed and used to evaluate a final mock TED Talk presented to faculty and students...
December 25, 2016: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28179715/integration-of-basic-and-clinical-science-courses-in-us-pharmd-programs
#11
Mohammed A Islam, Rahmat M Talukder, Reza Taheri, Nicholas Blanchard
Objective. To determine the current status of and faculty perceptions regarding integration of basic and clinical science courses in US pharmacy programs. Methods. A 25-item survey instrument was developed and distributed to 132 doctor of pharmacy (PharmD) programs. Survey data were analyzed using Mann-Whitney U test or Kruskal-Wallis test. Thematic analysis of text-based comments was performed using the constant comparison method. Results. One hundred twelve programs responded for a response rate of 85%. Seventy-eight (70%) offered integrated basic and clinical science courses...
December 25, 2016: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28178026/pelvic-floor-muscle-training-for-the-prevention-of-urinary-incontinence-in-antenatal-and-postnatal-women-a-best-practice-implementation-project
#12
Weijie Xing, Yu Zhang, Chunyi Gu, Lucylynn Lizarondo
BACKGROUND: Pregnancy and vaginal delivery may cause urinary incontinence (UI) in some women, which can impact on their quality of life. Pelvic floor muscles training (PFMT) is a safe and effective intervention for preventing UI associated with pregnancy. OBJECTIVES: The aim of this evidence-implementation project was to promote PFMT to prevent UI among antenatal and postnatal women in an obstetric and gynecological hospital in China. METHODS: A clinical audit was undertaken using the Joanna Briggs Institute Practical Application of Clinical Evidence System tool...
February 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28176333/selective-versus-routine-use-of-episiotomy-for-vaginal-birth
#13
REVIEW
Hong Jiang, Xu Qian, Guillermo Carroli, Paul Garner
BACKGROUND: Some clinicians believe that routine episiotomy, a surgical cut of the vagina and perineum, will prevent serious tears during childbirth. On the other hand, an episiotomy guarantees perineal trauma and sutures. OBJECTIVES: To assess the effects on mother and baby of a policy of selective episiotomy ('only if needed') compared with a policy of routine episiotomy ('part of routine management') for vaginal births. SEARCH METHODS: We searched Cochrane Pregnancy and Childbirth's Trials Register (14 September 2016) and reference lists of retrieved studies...
February 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28166080/stress-induced-gastric-ulcers-presenting-as-massive-rectal-bleeding-in-a-newborn
#14
A Joshi, P S Shrestha, S Dangol, N C Shrestha, P Poudyal, A Shrestha A
Severe gastrointestinal bleeding in newborn period is a serious but uncommon phenomenon that has a broad differential diagnosis. Primary duodenal ulcers are rare in children but stress induced ulceration in stomach occurs more often in neonatal period due to birth asphyxia, prolonged labour, cesarean deliveries, instrumentations, respiratory distress syndrome and sepsis. These present as acute onset of gastrointestinal bleeding commonly as altered gastric aspirate, hematemesis or malena. We report a case of a neonate with stress induced gastric bleeding following birth asphyxia who presented with massive gastrointestinal bleed manifesting as hematemesis and massive rectal bleeding...
April 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/28160187/a-multilevel-analysis-of-patient-engagement-and-patient-reported-outcomes-in-primary-care-practices-of-accountable-care-organizations
#15
Stephen M Shortell, Bing Ying Poon, Patricia P Ramsay, Hector P Rodriguez, Susan L Ivey, Thomas Huber, Jeremy Rich, Tom Summerfelt
BACKGROUND: The growing movement toward more accountable care delivery and the increasing number of people with chronic illnesses underscores the need for primary care practices to engage patients in their own care. OBJECTIVE: For adult primary care practices seeing patients with diabetes and/or cardiovascular disease, we examined the relationship between selected practice characteristics, patient engagement, and patient-reported outcomes of care. DESIGN: Cross-sectional multilevel observational study of 16 randomly selected practices in two large accountable care organizations (ACOs)...
February 3, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28159121/mode-of-delivery-among-swedish-midwives-and-obstetricians-and-their-attitudes-towards-caesarean-section
#16
Maria Sahlin, Ellika Andolf, Gunnar Edman, Ingela Wiklund
BACKGROUND: A knowledge gap exists around midwives' and obstetricians' mode of delivery in comparison to the general population, and if their personal experience influences their attitudes towards different modes of delivery. OBJECTIVES: The aim of the present study was to investigate midwives' and obstetricians' mode of delivery compared to the population at large. The second aim was to see if their mode of delivery had been influenced by the expanded indications for caesarean section as described in medical literature...
March 2017: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/28157647/redox-responsive-albumin-autogenic-nanoparticles-for-the-delivery-of-cancer-drugs
#17
S Thirupathi Kumara Raja, T Prakash, A Gnanamani
The present study explores preparation and characterization of redox sensitive albumin autogenic nanoparticles (ANPs) for drug delivery applications. Human serum albumin nanoparticles are prepared by desolvation method. The particles are stabilized through self-crosslinking and no external stabilizers are involved in the preparation. ANPs are then subjected to Camptothecin (CPT) drug loading. Experiments on in vitro and in vivo release profile, cytotoxic and cytocompatability, hemocompatability, blood clearance, tracking and bio imaging are studied in detail...
January 25, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28156540/family-camp-a-multi-disciplinary-intervention-for-brain-tumor-patients-and-families
#18
Mary Lovely, Abigail Levinson Marks, Amanda K LaMarre, Susan M Chang, Jennifer Clarke, Judy Patt, Emelia Barani
: 240 Background: The diagnosis of a brain tumor is a catastrophic life changing event that impacts the entire family. Patients and caregivers experience dramatic role changes, concern for their children, financial stress, and isolation. For many, the situation is overwhelming. A novel intervention to address these needs is "Family Camp". Our vision for camp was to provide respite to the entire family, decrease caregiver stress, improve family connections and promote a sense of understanding and connection with the community at large...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28153664/predicting-the-difficulty-of-operative-vaginal-delivery-by-ultrasound-measurement-of-fetal-head-station
#19
Sidi Kasbaoui, François Severac, Germain Aissi, A Gaudineau, Lise Lecointre, Chérif Akladios, R Favre, B Langer, N Sananes
BACKGROUND: Clinical assessment of fetal head station is difficult and subjective whereas it is mandatory before attempting operative vaginal delivery. OBJECTIVES: The principal objective of our study was to assess whether measurement of the perineum-to-skull ultrasound distance was predictive of a difficult operative vaginal delivery. Secondary objectives include evaluation of the inter-observer reproducibility of perineum-to-skull ultrasound distance and comparison of this measurement and digital examination in predicting a difficult operative delivery...
January 28, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28153654/reduction-of-total-labour-length-through-the-addition-of-parenteral-dextrose-solution-in-induction-of-labor-in-nulliparous-results-of-dextrons-prospective-randomized-controlled-trial
#20
Josianne Paré, Jean-Charles Pasquier, Antoine Lewin, William Fraser, Yves-André Bureau
BACKGROUND: Prolonged labor is a significant cause of maternal and fetal morbidity and very few interventions are known to shorten labor course. Skeletal muscle physiology suggests that glucose supplementation might improve muscle performance in case of prolonged exercise and this situation is analogous to the gravid uterus during delivery. Therefore, it seemed imperative to evaluate the impact of adding carbohydrate supplements on the course of labor. OBJECTIVE(S): To provide evidence as to whether IV glucose supplementation during labor induction in nulliparous women can reduce total duration of active labor...
January 28, 2017: American Journal of Obstetrics and Gynecology
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