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https://www.readbyqxmd.com/read/29778343/community-pharmacy-minor-ailment-services-in-england-pharmacy-stakeholder-perspectives-on-the-factors-affecting-sustainability
#1
Hamde Nazar, Zachariah Nazar
BACKGROUND: Self-care advice and management of minor ailments have long been provided in community pharmacies across England. However, formal pharmacy minor ailment service provision is geographically variable and has yet to gain recognition and political support as a valued sustainable service for nationwide adoption and commissioning. OBJECTIVE: To investigate the sustainability potential of pharmacy minor ailment services from the perspective of community pharmacy stakeholders within the North East of England...
May 14, 2018: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29770432/automated-mandatory-bolus-versus-basal-infusion-for-maintenance-of-epidural-analgesia-in-labour
#2
REVIEW
Ban Leong Sng, Yanzhi Zeng, Nurun Nisa A de Souza, Wan Ling Leong, Ting Ting Oh, Fahad Javaid Siddiqui, Pryseley N Assam, Nian-Lin R Han, Edwin Sy Chan, Alex T Sia
BACKGROUND: Childbirth may cause the most severe pain some women experience in their lifetime. Epidural analgesia is an effective form of pain relief during labour and is considered to be the reference standard. Traditionally epidural analgesia has been delivered as a continuous infusion via a catheter in the epidural space, with or without the ability for the patient to supplement the analgesia received by activating a programmable pump to deliver additional top-up doses, known as patient-controlled epidural analgesia (PCEA)...
May 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29769174/a-self-directed-mobile-intervention-waznapp-to-promote-weight-control-among-employees-at-a-lebanese-university-protocol-for-a-feasibility-pilot-randomized-controlled-trial
#3
Marco Bardus, Ghassan Hamadeh, Bouchra Hayek, Rawan Al Kherfan
BACKGROUND: Overweight and obesity have become major health problems globally with more than 1.9 billion overweight adults. In Lebanon, the prevalence of obesity and overweight is 65.4% combined. Risk factors of obesity and overweight are preventable and can be addressed by modifications in the environment and in an individual's lifestyle. Mobile technologies are increasingly used in behavioral, self-directed weight management interventions, providing users with additional opportunities to attain weight control (weight loss, weight gain prevention, etc)...
May 16, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29765207/adherence-to-antihyperglycemic-medications-and-glucagon-like-peptide-1-receptor-agonists-in-type-2-diabetes-clinical-consequences-and-strategies-for-improvement
#4
REVIEW
Francesco Giorgino, Alfred Penfornis, Valeria Pechtner, Raffaella Gentilella, Antonella Corcos
Adherence to antihyperglycemic medications is often suboptimal in patients with type 2 diabetes, and this can contribute to poor glycemic control, increased hospitalization, and the development of diabetic complications. Reported adherence rates to antihyperglycemics vary widely among studies, and this may be related to differences in methodology for measuring adherence, patient populations, and other factors. Poor adherence may occur regardless of the specific regimen used and whether therapy is oral or injectable, and can be especially common in chronic, asymptomatic conditions, such as type 2 diabetes...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29760030/nurse-practitioner-physician-comanagement-a-theoretical-model-to-alleviate-primary-care-strain
#5
Allison A Norful, Krystyna de Jacq, Richard Carlino, Lusine Poghosyan
PURPOSE: Various models of care delivery have been investigated to meet the increasing demands in primary care. One proposed model is comanagement of patients by more than 1 primary care clinician. Comanagement has been investigated in acute care with surgical teams and in outpatient settings with primary care physicians and specialists. Because nurse practitioners are increasingly managing patient care as independent clinicians, our study objective was to propose a model of nurse practitioner-physician comanagement...
May 2018: Annals of Family Medicine
https://www.readbyqxmd.com/read/29756460/inhaled-fasudil-lacks-pulmonary-selectivity-in-thromboxane-induced-acute-pulmonary-hypertension-in-newborn-lambs
#6
Shawn F L Hanson, Michael H Terry, Dafne T Moretta, Gordon G Power, Sean M Wilson, Farzana Alam, Fakhrul Ahsan, Arlin B Blood, Paresh C Giri
INTRODUCTION: Pulmonary hypertension (PH) is a potentially deadly disease for infants and adults with few existing medical interventions and no cure. In PH, increased blood pressure in the pulmonary artery eventually leads to heart failure. Fasudil, an antagonist of Rho-kinase, causes vasodilation leading to decreased systemic artery pressure and pulmonary artery pressure (PAP). This study compared the effects of fasudil administered as either an intravenous infusion or inhaled aerosol in newborn lambs...
January 1, 2018: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29747581/mother-to-child-transmission-of-hiv-infection-and-its-associated-factors-in-ethiopia-a-systematic-review-and-meta-analysis
#7
Getachew Mullu Kassa
BACKGROUND: Mother-to-child transmission (MTCT) is the main mode of HIV transmission in children under 15 years old. This problem is significant in the Sub-Saharan African countries, where more than 80% of children living with HIV are found. Previous studies in Ethiopia present inconsistent and inconclusive findings on the prevalence and associated factors of MTCT of HIV. Therefore, this study was conducted to determine the pooled prevalence of MTCT of HIV and its associated factors in Ethiopia...
May 10, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29746561/monitoring-food-pathogens-novel-instrumentation-for-cassette-pcr-testing
#8
Darin Hunt, Curtis Figley, Dammika P Manage, Jana Lauzon, Rachel Figley, Linda M Pilarski, Lynn M McMullen, Patrick M Pilarski
In this manuscript, we report the design and development of a fast, reliable instrument to run gel-based cassette polymerase chain reactions (PCR). Here termed the GelCycler Mark II, our instrument is a miniaturized molecular testing system that is fast, low cost and sensitive. Cassette PCR utilizes capillary reaction units that carry all reagents needed for PCR, including primers and Taq polymerase, except the sample, which is loaded at the time of testing. Cassette PCR carries out real time quantitative PCR followed by melt curve analysis (MCA) to verify amplicon identity at the expected melt temperature (Tm)...
2018: PloS One
https://www.readbyqxmd.com/read/29743219/clinician-experiences-with-screening-for-social-needs-in-primary-care
#9
Sebastian T Tong, Winston R Liaw, Paulette Lail Kashiri, James Pecsok, Julia Rozman, Andrew W Bazemore, Alex H Krist
BACKGROUND: Despite clear evidence demonstrating the influence of social determinants on health, whether and how clinicians should address these determinants remain unclear. We aimed to understand primary care clinicians' experiences of administering a social needs screening instrument. METHODS: Using a prospective, observational design, we identified patients living in communities with lower education and income seen by 17 clinicians from 12 practices in northern Virginia...
May 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29743028/investigating-determinants-for-patient-satisfaction-in-women-receiving-epidural-analgesia-for-labour-pain-a-retrospective-cohort-study
#10
Daryl Jian An Tan, Rehena Sultana, Nian Lin Reena Han, Alex Tiong Heng Sia, Ban Leong Sng
BACKGROUND: Epidural analgesia is a popular choice for labour pain relief. Patient satisfaction is an important patient-centric outcome because it can significantly influence both mother and child. However, there is limited evidence in the correlations between clinical determinants and patient satisfaction. We aim to investigate clinical covariates that are associated with low patient satisfaction in parturients receiving labour neuraxial analgesia. METHODS: After institutional ethics approval was obtained, we conducted a retrospective cohort study using electronic and corresponding hardcopy records from 10,170 parturients receiving neuraxial analgesia between the periods of January 2012 to December 2013 in KK Women's and Children's Hospital in Singapore...
May 9, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29742281/analyzing-the-clinical-actionability-of-germline-pharmacogenomic-findings-in-oncology
#11
Rebecca Wellmann, Brittany A Borden, Keith Danahey, Rita Nanda, Blase N Polite, Walter M Stadler, Mark J Ratain, Peter H O'Donnell
BACKGROUND: Germline and tumor pharmacogenomics impact drug responses, but germline markers less commonly guide oncology prescribing. The authors hypothesized that a critical number of clinically actionable germline pharmacogenomic associations exist, representing clinical implementation opportunities. METHODS: In total, 125 oncology drugs were analyzed for positive germline pharmacogenomic associations in journals with impact factors ≥5. Studies were assessed for design and genotyping quality, clinically relevant outcomes, statistical rigor, and evidence of drug-gene effects...
May 9, 2018: Cancer
https://www.readbyqxmd.com/read/29742273/efficacy-of-an-educational-manual-for-childbirth-companions-pilot-study-of-a-randomized-clinical-trial
#12
Liana Mara Rocha Teles, Camila Félix Américo, Mônica Oliveira Batista Oriá, Camila Teixeira Moreira Vasconcelos, Odaléa Maria Brüggemann, Ana Kelve de Castro Damasceno
OBJECTIVE: to evaluate the effectiveness of an educational manual in the instrumentalization of companions to provide support to the parturients and check its influence on the satisfaction of companions and women during vaginal delivery. METHOD: pilot study of a randomized controlled clinical trial with 65 companions and puerperal women (intervention = 21 and control = 44). The previous knowledge of the companions was evaluated at baseline. The Evaluation Form for Companions in the Delivery Room was used to measure the actions provided and the satisfaction with the experience, and the Questionnaire for Evaluation of the Experience and Satisfaction of Puerperal Women with Labor and Delivery was used to evaluate the satisfaction of women with childbirth...
2018: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/29735455/-efficacy-of-ropivacaine-injection-at-acupoints-for-labor-analgesia-and-its-effect-on-cortisol-level-in-parturients
#13
Xiang-Nan Chen, Shi-Hui Yang, Hui-Rui Lin, Ning-Ning Chen, Chen-Lu Su, Wei Huang
OBJECTIVE: To evaluate the efficacy of ropivacaine injection at the acupoints Hegu and Sanyinjiao for labor analgesia and its effects on cortisol level in parturients. METHODS: A total of 120 ASA class I-II nulliparous women undergoing spontaneous term labor (37 to 41 weeks of gestation) with a live, singleton fetus in the occiput anterior position and requiring labor analgesia with acupuncture were enrolled in this study. These women were randomized into study group and control group and received injections of 1 mL of 0...
April 20, 2018: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/29734121/factors-associated-with-obstetric-anal-sphincter-injuries-in-midwife-led-birth-a-cross-sectional-study
#14
Jorunn Wik Tunestveit, Elham Baghestan, Gerd Karin Natvig, Geir Egil Eide, Anne Britt Vika Nilsen
INTRODUCTION: Obstetric anal sphincter injurie (OASI) in vaginal births are a serious complication, and are associated with maternal morbidity. Focus on modifiable factors in midwives clinical skills and competences contributing to prevent the occurrence of OASI are essential. The objective of this study was to investigate the association between OASI and factors related to midwife-led birth such as manual support of perineum, active delivery of baby's shoulders, maternal birth position, and pushing and breathing techniques in second stage of labour...
April 21, 2018: Midwifery
https://www.readbyqxmd.com/read/29733366/the-use-of-the-patient-assessment-of-chronic-illness-care-pacic-instrument-in-diabetes-care-a-systematic-review-and-meta-analysis
#15
Chantal Arditi, Katia Iglesias, Isabelle Peytremann-Bridevaux
Purpose: The Patient Assessment of Chronic Illness Care (PACIC) was created to assess whether provided care is congruent with the Chronic Care Model, according to patients. We aimed to identify all studies using the PACIC in diabetic patients to explore (i) how overall PACIC scores varied across studies and (ii) whether scores varied according to healthcare delivery, patient and instrument characteristics. Data sources: MEDLINE, Embase, PsycINFO, CINAHL and PubMed Central (PMC), from 2005 to 2016...
May 4, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29731612/developing-and-piloting-an-instrument-to-prioritize-the-worries-of-patients-with-acute-myeloid-leukemia
#16
John Fp Bridges, Allison H Oakes, Crystal A Reinhart, Ernest Voyard, Bernadette O'Donoghue
Background: Acute myeloid leukemia (AML) is a rapidly progressing blood cancer for which new treatments are needed. We sought to promote patient-focused drug development (PFDD) for AML by developing and piloting an instrument to prioritize the worries of patients with AML. Patients and methods: An innovative community-centered approach was used to engage expert and community stakeholders in the development, pretesting, pilot testing, and dissemination of a novel best-worst scaling instrument...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29718920/placental-cord-drainage-in-the-third-stage-of-labor-randomized-clinical-trial
#17
Fernanda Barros Vasconcelos, Leila Katz, Isabela Coutinho, Vanessa Laranjeiras Lins, Melania Maria de Amorim
METHODS: An open randomized clinical trial was developed at Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) in Recife and at Petronila Campos Municipal Hospital in São Lourenço da Mata, both in Pernambuco, northeastern Brazil, including 226 low-risk pregnant women bearing a single, full-term, live fetus after delayed cord clamping, 113 randomized to placental cord drainage and 113 to a control group not submitted to this procedure. Women incapable of understanding the study objectives and those who went on to have an instrumental or cesarean delivery were excluded...
2018: PloS One
https://www.readbyqxmd.com/read/29709434/no-effect-of-music-on-anxiety-and-pain-during-transrectal-prostate-biopsies-a-randomized-trial
#18
Vignesh T Packiam, Charles U Nottingham, Andrew J Cohen, Scott E Eggener, Glenn S Gerber
OBJECTIVE: To investigate the effect of ambient music on anxiety and pain in men undergoing prostate biopsies. METHODS: Between September 2015 and June 2016, men undergoing office transrectal prostate biopsy at our institution were randomly assigned to music (n=85) or control (n=97) groups. We examined clinical characteristics, pathologic variables, and baseline anxiety using the Trait Instrument of State-Trait Anxiety Inventory (STAI-T). Primary outcomes included anxiety assessed by State Instrument of STAI (STAI-S) and pain using a Visual Analog Scale (VAS)...
April 27, 2018: Urology
https://www.readbyqxmd.com/read/29701287/being-respected-by-nurses-measuring-older-patients-perceptions
#19
Jaana Koskenniemi, Helena Leino-Kilpi, Pauli Puukka, Minna Stolt, Riitta Suhonen
AIM AND OBJECTIVE: To investigate older patients' perceptions of respect in hospital nursing care and to test a newly developed instrument measuring the phenomenon. BACKGROUND: Respect manifests itself in the older patient-nurse relationship in terms of nurses being with and doing for the patient. Empirical studies investigating respect from the older patients' perspective are rare. There is a need to maintain respectful behaviours and attitudes within hospital-based nursing practice...
April 27, 2018: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/29700831/reliability-of-the-australian-therapy-outcome-measures-for-occupational-therapy-austoms-ot
#20
Carolyn A Unsworth, Amanda Timmer, Kylie Wales
BACKGROUND/AIM: The delivery of evidence-based health care requires the routine adoption of outcome measures that are valid and reliable. The Australian Therapy Outcome Measures for Occupational Therapy (AusTOMs-OT) was developed in Australia to capture a global snapshot of status for any client, and has preliminary psychometric evidence to support use. Building on the psychometric evidence of the AusTOMs-OT will provide therapists and researchers with further information as to how best to apply the AusTOMs-OT in their field...
April 26, 2018: Australian Occupational Therapy Journal
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