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https://www.readbyqxmd.com/read/27906196/population-based-reference-curve-for-umbilical-cord-arterial-ph-in-infants-born-at-28-to-42-weeks
#1
B Skiöld, G Petersson, M Ahlberg, O Stephansson, S Johansson
OBJECTIVE: The objective of the study was to examine normal variations of umbilical cord arterial pH by gestational age (GA). STUDY DESIGN: Population-based cohort study of 46 199 infants born from 2008 to 2014 in Stockholm, Sweden, with GA 28 to 42 weeks, Apgar score ⩾7 at 5 min, non-instrumental vaginal delivery, and birth weight for GA⩾3rd and ⩽97th percentile. Quantile regression was used to investigate the associations between GA and infant sex, and pH...
December 1, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27905982/the-use-of-a-lot-quality-assurance-sampling-methodology-to-assess-and-manage-primary-health-interventions-in-conflict-affected-west-darfur-sudan
#2
Kiemanh Pham, Emily Chambers Sharpe, William M Weiss, Alexander Vu
BACKGROUND: Organizations working in conflict-affected areas have a need to monitor and evaluate their programs, however this is often difficult due to the logistical challenges of conflict areas. Lot quality assurance sampling may be a suitable method of assessing programs in these situations. METHODS: We conducted a secondary data analysis of information collected during Medair's routine program management functions. Medair's service area in West Darfur, Sudan was divided into seven supervisory areas...
October 6, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905069/pavlovian-reward-learning-underlies-value-driven-attentional-capture
#3
Berno Bucker, Jan Theeuwes
Recent evidence shows that distractors that signal high compared to low reward availability elicit stronger attentional capture, even when this is detrimental for task-performance. This suggests that simply correlating stimuli with reward administration, rather than their instrumental relationship with obtaining reward, produces value-driven attentional capture. However, in previous studies, reward delivery was never response independent, as only correct responses were rewarded, nor was it completely task-irrelevant, as the distractor signaled the magnitude of reward that could be earned on that trial...
November 30, 2016: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/27903195/dosimetric-effects-of-onyx-embolization-on-gamma-knife-arteriovenous-malformation-dose-distributions
#4
David J Schlesinger, Håkan Nordström, Anders Lundin, Zhiyuan Xu, Jason P Sheehan
OBJECTIVE Patients with arteriovenous malformations (AVMs) treated with Gamma Knife radiosurgery (GKRS) subsequent to embolization suffer from elevated local failure rates and differences in adverse radiation effects. Onyx is a common embolic material for AVMs. Onyx is formulated with tantalum, a high atomic number (Z = 73) element that has been investigated as a source of dosimetric uncertainty contributing to the less favorable clinical results. However, prior studies have not modeled the complicated anatomical and beam geometries characteristic of GKRS...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27896539/why-health-and-social-care-support-for-people-with-long-term-conditions-should-be-oriented-towards-enabling-them-to-live-well
#5
Vikki A Entwistle, Alan Cribb, John Owens
There are various reasons why efforts to promote "support for self-management" have rarely delivered the kinds of sustainable improvements in healthcare experiences, health and wellbeing that policy leaders internationally have hoped for. This paper explains how the basis of failure is in some respects built into the ideas that underpin many of these efforts. When (the promotion of) support for self-management is narrowly oriented towards educating and motivating patients to adopt the behaviours recommended for disease control, it implicitly reflects and perpetuates limited and somewhat instrumental views of patients...
November 28, 2016: Health Care Analysis: HCA: Journal of Health Philosophy and Policy
https://www.readbyqxmd.com/read/27889574/budesonide-oral-suspension-improves-symptomatic-endoscopic-and-histologic-parameters-compared-with-placebo-in-patients-with-eosinophilic-esophagitis
#6
Evan S Dellon, David A Katzka, Margaret H Collins, Mohamed Hamdani, Sandeep K Gupta, Ikuo Hirano
BACKGROUND & AIMS: Pharmacologic treatment of eosinophilic esophagitis (EoE) is limited to off-label use of corticosteroids not optimized for esophageal delivery. We performed a randomized, controlled phase 2 trial to assess the ability of budesonide oral suspension (BOS), a novel muco-adherent topical steroid formulation, to reduce symptoms and esophageal eosinophilia in adolescents and adults with EoE. METHODS: In this multicenter, randomized, double-blind, placebo-controlled, parallel-group trial, 93 EoE patients between the ages of 11 and 40 years with dysphagia and active esophageal eosinophilia were randomized to receive either BOS 2 mg or placebo twice daily for 12 weeks...
November 23, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27889256/controlled-human-infection-with-rsv-the-opportunities-of-experimental-challenge
#7
Maximillian S Habibi, Christopher Chiu
Despite the recent explosion in RSV vaccine development, there remain substantial hurdles to overcome before licensing of effective vaccines will allow widespread use, particularly in high-risk populations. Incomplete understanding of mechanisms and correlates of protection against RSV mean that, for the time being, successful RSV vaccines must directly demonstrate efficacy, which necessitates large and costly clinical trials in naturally infected patients. To mitigate the risks inherent in progressing to these late-stage trials, experimental human RSV infection studies have recently been re-established, representing the interface between pre-clinical models and observational studies of patients...
November 23, 2016: Vaccine
https://www.readbyqxmd.com/read/27886376/-the-burden-of-pregnancy-heavier-for-the-heaviest-the-changes-in-health-related-quality-of-life-hrqol-assessed-by-the-15d-instrument-during-pregnancy-and-postpartum-in-different-body-mass-index-groups-a-longitudinal-survey
#8
Niina Sahrakorpi, Saila B Koivusalo, Beata Stach-Lempinen, Johan Gunnar Eriksson, Hannu Kautiainen, Risto Roine
INTRODUCTION: Only little information is available on health-related quality of life (HRQoL) and its changes during the course of a normal pregnancy. We studied changes in HRQoL in a pregnant population during pregnancy and until one year postpartum in different body mass index (BMI) groups. MATERIAL AND METHODS: 750 pregnant women attending the first ultrasound examination before gestational week 14 were invited to participate in a longitudinal, communal-based survey...
November 25, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27881782/consolidation-of-goal-directed-action-depends-on-mapk-erk-signaling-in-rodent-prelimbic-cortex
#9
Genevra Hart, Bernard W Balleine
: The prelimbic prefrontal cortex (PL) has consistently been found to be necessary for the acquisition of goal-directed actions in rodents. Nevertheless, the specific cellular processes underlying this learning remain unknown. We assessed changes in learning-related expression of mitogen-activated protein kinase/extracellular signal-related kinase (MAPK/ERK1/2) phosphorylation (pERK) in layers 2-3 and 5-6 of the anterior and posterior PL and in the population of neurons projecting to posterior dorsomedial striatum (pDMS), also implicated in goal-directed learning...
November 23, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27881697/adult-day-services-outcomes-delphi-review-of-an-integrated-participant-assessment-system
#10
Shannon Jarrott, Aaron M Ogletree
Adult day services (ADS) aim to help elders age in place, but evidence of impact on participants lags behind caregiver research. To play a larger role in the continuum of care, ADS participant outcomes should regularly be documented with standard measures. We conducted a Delphi review of one integrated participant assessment system. Capturing physical, mental, and cognitive health indicators and activity engagement of typical ADS participants (i.e., frail elders eligible for nursing home placement), experts evaluated the system on instrument validity, relevance, and application...
November 22, 2016: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/27875504/screening-for-psychosocial-and-family-risk-in-pediatric-gastrointestinal-disorders
#11
Carin Cunningham, Elise Cho, Michele L Shaffer, Miranda C Bradford, Tonya Palermo
OBJECTIVES: Screening for psychosocial comorbidity is recommended for pediatric patients presenting at an initial gastroenterology (GI) outpatient consultation. We developed and evaluated the psychometric properties of the GI Screener to address the need for a screening tool specific to pediatric GI patients. METHODS: 128 patients (8-18 years old, 63% female) and 126 parents completed age-specific versions of the GI Screener and 3 validated psychosocial comparison instruments (The Behavioral Assessment System for Children, The Functional Disability Inventory, The General Functioning scale of the Family Assessment Device) at their initial GI consultation...
December 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27869984/cesarean-delivery-rates-and-obstetric-culture-an-italian-register-based-study
#12
Cristina Plevani, Maddalena Incerti, Davide Del Sorbo, Armando Pintucci, Patrizia Vergani, Luca Merlino, Anna Locatelli
INTRODUCTION: Cesarean delivery (CD) rates are rising due to multiple factors, including less use of operative vaginal delivery (OVD) and vaginal birth after cesarean delivery (VBAC), which often reflect local obstetric practices. Objectives of the study were to analyze the relations between CD, these practices and perinatal outcomes. MATERIAL AND METHODS: We included all deliveries in the 72 hospitals of Lombardia, a Region in Northern Italy, during the year 2013...
November 21, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27868351/essential-elements-of-the-nursing-practice-environment-in-nursing-homes-psychometric-evaluation
#13
Brigitte Johanna Maria de Brouwer, Marian J Kaljouw, Lisette Schoonhoven, Theo van Achterberg
AIMS AND OBJECTIVES: To develop and psychometrically test the Essentials of Magnetism II in nursing homes. BACKGROUND: Increasing numbers and complex needs of older people in nursing homes strain the nursing workforce. Fewer adequately trained staff and increased care complexity raise concerns about declining quality. Nurses' practice environment has been reported to affect quality of care and productivity. The Essentials of Magnetism II © measures processes and relationships of practice environments that contribute to productivity and quality of care and can therefore be useful in identifying processes requiring change to pursue excellent practice environments...
November 20, 2016: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/27868224/evaluation-of-levator-ani-muscle-throughout-the-different-stages-of-labor-by-transperineal-3d-ultrasound
#14
José Antonio García Mejido, Carmen M Suárez Serrano, Ana Fernéndez Palacín, Adriana Aquise Pino, María José Bonomi Barby, José Antonio Sainz Bueno
OBJECTIVE: Description and assessment by 3-D transperineal ultrasound of modifications suffered by pelvic floor muscles during the passage of the fetal head through the birth canal during the second stage of labor, as well as the identification of the precise moment in which levator ani muscle avulsion takes place. MATERIALS AND METHODS: Patients included were 35 primigravidae, recruited during the first stage of labor, with at term pregnancy (37-42 weeks), without serious maternal-fetal pathology and cephalic presentation...
November 21, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27867946/advances-in-fetal-surgery
#15
REVIEW
Kathryn M Maselli, Andrea Badillo
Historically, the gold standard for the treatment of congenital malformations has been planned delivery at tertiary care center with attempted post-natal repair or amelioration of the lesion. Over the last few decades however, rapid advances in imaging and instrumentation technology combined with superior knowledge of fetal pathophysiology has led to the development of novel intrauterine interventions for most common fetal anomalies. Great success has already been seen the treatment of previous devastating anomalies such as myelomeningocele (MMC), congenital cystic malformations of the lung, twin-twin transfusion, and sacrococcygeal teratomas...
October 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27846123/patient-nursing-and-medical-staff-experiences-and-perceptions-of-the-care-of-people-with-palliative-esophagogastric-cancer-a-systematic-review-of-the-qualitative-evidence
#16
Alison Cowley, Catrin Evans, Fiona Bath-Hextall, Joanne Cooper
BACKGROUND: Esophagogastric cancer is the fifth most common malignancy and its incidence is increasing. The disease progresses quickly and five-year survival rates are poor. Treatment with palliative intent is provided for the majority of patients but there remains a lack of empirical evidence on the most effective service models to support esophagogastric cancer patients. OBJECTIVES: The overall objective of this systematic review was to synthesize the best available evidence on the experiences and perceptions of patients and health professionals with regard to the care of people diagnosed with palliative esophagogastric cancer...
October 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27842580/the-effect-of-written-standardized-feedback-on-the-structure-and-quality-of-surgical-lectures-a-prospective-cohort-study
#17
Jasmina Sterz, Sebastian H Höfer, Bernd Bender, Maren Janko, Farzin Adili, Miriam Ruesseler
BACKGROUND: Lectures remain an important teaching method to present and structure knowledge to many students concurrently. Adequate measures are necessary to maintain the quality of the lectures. The aim of this study was to determine the impact on the lecture quality using written structured feedback and to compare the ratings of surgical lectures between students and surgical peers. METHODS: Prospective analysis of two consecutive surgical lecture series for undergraduate students at Goethe-University Medical School was performed before and after evaluation of the lecturers via independent written feedback from trained undergraduate students and surgeons...
November 14, 2016: BMC Medical Education
https://www.readbyqxmd.com/read/27842564/heel-pressure-ulcer-prevention-and-predictors-during-the-care-delivery-chain-when-and-where-to-take-action-a-descriptive-and-explorative-study
#18
Åsa Muntlin Athlin, Maria Engström, Lena Gunningberg, Carina Bååth
BACKGROUND: Hazardous healthcare settings, for example acute care, need to focus more on preventing adverse events and preventive actions across the care delivery chain (i.e pre-hospital and emergency care, and further at the hospital ward) should be more studied. Pressure ulcer prevalence is still at unreasonably high levels, causing increased healthcare costs and suffering for patients. Recent biomedical research reveals that the first signs of cell damage could arise within minutes...
November 14, 2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/27833251/cross-sectional-study-on-the-obstetric-performance-of-primigravidae-in-a-teaching-hospital-in-lagos-nigeria
#19
Kehinde Sharafadeen Okunade, Halimat Okunola, Lawal Oyeneyin, Fatimah N Habeeb-Adeyemi
BACKGROUND: A woman carrying her first pregnancy is starting a new life, and this is a crucial time in her obstetric career. This study was aimed to compare the obstetric performance of primigravidae to that of the multigravidae with a view to suggesting ways of preventing the associated complications. PATIENTS AND METHODS: The study was a cross-sectional case-control study carried out among women who delivered in the study center over a year period. Relevant data of primigravid parturients who delivered in the hospital were retrieved from the labor ward register, and an equal number of multigravidae who delivered during the same study were selected by simple random sampling as the control group...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27831833/direct-concurrent-comparison-of-multiple-pediatric-acute-asthma-scoring-instruments
#20
Michael D Johnson, Flory L Nkoy, Xiaoming Sheng, Tom Greene, Bryan L Stone, Jennifer Garvin
OBJECTIVE: Appropriate delivery of Emergency Department (ED) treatment to children with acute asthma requires clinician assessment of acute asthma severity. Various clinical scoring instruments exist to standardize assessment of acute asthma severity in the ED, but their selection remains arbitrary due to few published direct comparisons of their properties. Our objective was to test the feasibility of directly comparing properties of multiple scoring instruments in a pediatric ED. METHODS: Using a novel approach supported by a composite data collection form, clinicians categorized elements of 5 scoring instruments before and after initial treatment for 48 patients 2-18 years of age with acute asthma seen at the emergency department of a tertiary care pediatric hospital ED from August to December 2014...
November 10, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
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