Guillaume Thizy, Adrien Flahault, Anne Scemla, Olivier Roux, Sophie Jarraud, David Lebeaux, Jacques Pouchot, Gabriela Gautier-Vargas, Paolo Malvezzi, Marlene Murris, Fanny Vuotto, Sophie Girerd, Nathalie Pansu, Teresa Antonini, Laure Elkrief, Benoit Barrou, Camille Besch, Mathieu Blot, Aude Boignard, Henri Brenier, Audrey Coilly, Corentin Gouezel, Kaminski Hannah, Pauline Housssel-Debry, Jerome Jouan, Hervé Lecuyer, Anne Limelette, Charles Edouard Luyt, Boris Melloni, Christophe Pison, Cédric Rafat, Jean-Michel Rebibou, Eric Savier, Betoul Schvartz, Olivier Scatton, Fatouma Toure, Shaida Varnous, Pauline Vidal, Emilie Savoye, Florence Ader, Olivier Lortholary, Fanny Lanternier, Emmanuel Lafont
BACKGROUND: Legionnaires' disease (LD) is a rare, life-threatening opportunistic bacterial infection that poses a significant risk to patients with impaired cell-mediated immunity such as solid organ transplant recipients (SOTRs). However, the epidemiologic features, clinical presentation, and outcomes of LD in this population are poorly described. RESEARCH QUESTION: What are the clinical manifestations, radiologic presentation, risk factors for severity, treatment, and outcome of LD in SOTRs? STUDY DESIGN AND METHODS: In this 10-year multicenter, retrospective cohort study in France, where LD notification is mandatory, patients were identified by hospital discharge databases...
October 14, 2023: Chest