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https://www.readbyqxmd.com/read/28758041/an-unusual-cause-of-intestinal-obstruction-in-a-young-adult-patient-inflammatory-fibroid-polyp
#1
Meryem Rais, Hafsa Chahdi, Mohammed Elfahssi, Abderrahmane Albouzidi, Mohamed Oukabli
Inflammatory fibroid polyps are uncommon benign lesions that originate in the submucosa of the gastrointestinal tract. The stomach and the ileum are the most commonly affected sites. Although inflammatory fibroid polyp is one of the rare conditions leading to intestinal obstruction in adults, it should be considered as a possible diagnosis in obstructive tumors of the small bowel causing intussusceptions. We present one case of inflammatory fibroid polyp as a rare cause of intussusception in a young adult patient...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28710577/detection-of-small-bowel-tumours-with-ct-enteroclysis-using-carbon-dioxide-and-virtual-enteroscopy-a-preliminary-study
#2
Anthony Dohan, Mourad Boudiaf, Xavier Dray, Elia Samaha, Christophe Cellier, Marine Camus, Clarisse Eveno, Raphael Dautry, Philippe Soyer
PURPOSE: The aim of this prospective study was to evaluate the feasibility, tolerance and performance of virtual enteroscopy (VE) using carbon dioxide for small-bowel distension in patients with suspected small-bowel tumours (SBTs). PATIENTS AND METHODS: After IRB approval, 17 patients with suspected SBTs were prospectively included. Radiation dose was compared to 34 matched patients (2 for 1) for age, gender and body weight, who had undergone CT-enteroclysis with neutral contrast (CTE)...
July 14, 2017: European Radiology
https://www.readbyqxmd.com/read/28685081/clinical-endoscopic-and-pathological-characteristics-of-colorectal-polyps-in-elderly-patients-single-center-experience
#3
Lei Zhou, Heng Zhang, Shengbin Sun, Manling Huang, Jing Liu, Dan Xu, Min Song, Chenming Sun, Hui Li, Dan Zheng, Yan Fan, Yusheng Liao, Ping Wang, Jie Wu
Increasing age is a risk factor for the development of colorectal adenomas and advanced adenomas. However, few studies have been published on the features of colorectal polyps in the elderly. The present study aimed to investigate the clinical, enteroscopic and pathological characteristics of colorectal polyps in Chinese elderly patients in a single center (The Central Hospital of Wuhan, Hubei, China). The endoscopic and pathological reports of colonoscopies performed in our center were retrospectively analyzed...
July 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28643886/ileocolic-intussusception-from-an-inflammatory-fibroid-polyp-a-rare-cause-of-adult-small-bowel-obstruction
#4
Sabrina Mader, Joseph Ting, Hajir Nabi
No abstract text is available yet for this article.
June 23, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28621643/the-clinical-effectiveness-of-different-surveillance-strategies-to-prevent-colorectal-cancer-in-people-with-intermediate-grade-colorectal-adenomas-a-retrospective-cohort-analysis-and-psychological-and-economic-evaluations
#5
Wendy Atkin, Amy Brenner, Jessica Martin, Katherine Wooldrage, Urvi Shah, Fiona Lucas, Paul Greliak, Kevin Pack, Ines Kralj-Hans, Ann Thomson, Sajith Perera, Jill Wood, Anne Miles, Jane Wardle, Benjamin Kearns, Paul Tappenden, Jonathan Myles, Andrew Veitch, Stephen W Duffy
BACKGROUND: The UK guideline recommends 3-yearly surveillance for patients with intermediate-risk (IR) adenomas. No study has examined whether or not this group has heterogeneity in surveillance needs. OBJECTIVES: To examine the effect of surveillance on colorectal cancer (CRC) incidence; assess heterogeneity in risk; and identify the optimum frequency of surveillance, the psychological impact of surveillance, and the cost-effectiveness of alternative follow-up strategies...
April 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28615131/stimulation-of-colorectal-biopsies-from-miniature-dachshunds-with-inflammatory-colorectal-polyps-with-toll-like-receptor-ligands-a-pilot-study
#6
Nozomu Yokoyama, Hiroshi Ohta, Yumiko Kagawa, Noriyuki Nagata, Khoirun Nisa, Tomoya Morita, Tatsuyuki Osuga, Noboru Sasaki, Keitaro Morishita, Kensuke Nakamura, Mitsuyoshi Takiguchi
Inflammatory colorectal polyps (ICRPs) in miniature dachshunds (MDs) are a possible novel form of breed-specific canine inflammatory bowel disease (IBD). In this pilot study, we investigated the effects of different Toll like receptor (TLR2, TLR4, TLR5 and TLR9) ligands on pro-inflammatory cytokines (IL-1β, IL-6, IL-8 and TNF-α) gene expression in ex vivo-cultured colorectal samples from four MDs with ICRPs and four healthy MDs. At baseline, no significant difference in the mRNA expression levels of TLRs and pro-inflammatory cytokines was observed between cases and control MDs...
June 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28596986/international-core-curriculum-for-capsule-endoscopy-training-courses
#7
Ignacio Fernandez-Urien, Simon Panter, Cristina Carretero, Carolyn Davison, Xavier Dray, Evgeny Fedorov, Richard Makins, Miguel Mascarenhas, Mark McAlindon, Deirdre McNamara, Hansa Palmer, Jean Francoise Rey, Jean Christophe Saurin, Uwe Seitz, Cristiano Spada, Ervin Toth, Felix Wiedbrauck, Martin Keuchel
Capsule endoscopy (CE) has become a first-line noninvasive tool for visualisation of the small bowel (SB) and is being increasingly used for investigation of the colon. The European Society of Gastrointestinal Endoscopy (ESGE) guidelines have specified requirements for the clinical applications of CE. However, there are no standardized recommendations yet for CE training courses in Europe. The following suggestions in this curriculum are based on the experience of European CE training courses directors. It is suggested that 12 hours be dedicated for either a small bowel capsule endoscopy (SBCE) or a colon capsule endoscopy (CCE) course with 4 hours for an introductory CCE course delivered in conjunction with SBCE courses...
June 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28567375/video-capsule-colonoscopy-in-routine-clinical-practice
#8
Ervin Toth, Diana E Yung, Artur Nemeth, Gabriele Wurm Johansson, Henrik Thorlacius, Anastasios Koulaouzidis
BACKGROUND: Colon capsule endoscopy (CCE) offers direct mucosal visualisation without sedation or gas insufflation required in conventional colonoscopy (CC). However, evidence for the role of CCE as an adjunct or alternative to CC remains equivocal. In this observational cohort study, we report our experience of using CCE to investigate patients with suspected colon pathology at a tertiary referral centre. METHODS: From 2007-2015, consecutive patients requiring colonoscopy were recruited from a tertiary care centre in Malmo, Sweden...
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28567116/efficacy-of-double-balloon-enteroscopy-for-small-bowel-polypectomy-clinical-and-economic-evaluation
#9
Gabriel Rahmi, Marie-Amélie Vinet, Guillaume Perrod, Jean-Christophe Saurin, Elia Samaha, Thierry Ponchon, Jean-Marc Canard, Joël Edery, Hassani Maoulida, Gilles Chatellier, Isabelle Durand-Zaleski, Christophe Cellier
BACKGROUND: We evaluated first the feasibility of endoscopic small-bowel polypectomy and second, the economic aspects, by comparing the cost of endoscopic and surgical polyp resection. METHODS: A prospective, observational, multicenter study included 494 patients with positive capsule endoscopy (CE) before double-balloon enteroscopy (DBE). We selected only CE with at least one polyp. The retrospective economic evaluation compared patients treated by DBE or surgery for small-bowel polypectomy...
June 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28319601/effectiveness-of-double-balloon-enteroscopy-facilitated-polypectomy-in-paediatric-patients-with-peutz-jeghers-syndrome
#10
Dalia Belsha, Arun Urs, Thomas Attard, Mike Thomson
BACKGROUND: Sizable small-bowel (SB) polyps in Peutz-Jeghers syndrome (PJS) pose a high risk for intussusception, often necessitating laparotomy and intraoperative-enteroscopy (IOE). This series examines the effectiveness of double-balloon enteroscopy (DBE) facilitated polypectomy for pediatric patients with PJS. METHODS: Prospective analysis of collected data (6 years) on all patients with PJS referred for DBE-facilitated SB polypectomy at a pediatric tertiary-referral center...
March 17, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28314199/unusual-ultrasound-appearance-of-small-bowel-intussusception-and-secondary-bowel-obstruction-in-a-child-with-peutz-jeghers-syndrome
#11
Lei Wu, Ramesh S Iyer, George T Drugas, A Luana Stanescu
Small bowel intussusception (SBI) in pediatric patients resolves spontaneously in the majority of cases. Pathologic small bowel intussusception with a lead point is rare in children. Ultrasound (US) is the preferred initial imaging study for the diagnosis of intussusception. We report a case of long-segment SBI and secondary bowel obstruction caused by a large hamartomatous polyp. This case emphasizes unique, atypical ultrasound findings that may be encountered in small bowel intussusception, with correlative radiographic, CT (computed tomography) and intra-operative findings...
May 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28303455/duodenal-cancer-in-a-young-patient-with-peuts-jeghers-syndrome-harboring-an-entire-deletion-of-the-stk11-gene
#12
Satoshi Teramae, Koichi Okamoto, Kumiko Tanaka, Reika Matsumoto, Shinji Kitamura, Tetsuo Kimura, Masahiro Sogabe, Hiroshi Miyamoto, Naoki Muguruma, Yoshimi Bando, Mitsuo Shimada, Tetsuji Takayama
A 21-year-old woman with Peuts-Jeghers syndrome (PJS) was referred to our hospital for gastrointestinal surveillance. She had been diagnosed as having PJS from a young age based on her family history and the presence of mucocutaneous pigmentation on her lips and oral mucosa. Her mother and brother had PJS harboring an entire deletion of the STK11 gene. She had tetralogy of Fallot, atrial tachycardia, sick sinus syndrome, and mental retardation in her past history. Esophagogastroduodenoscopy identified a protruded lesion with a depressed area that occupied the lumen half-circumferentially in the duodenal second portion and also showed a 10-mm protruded lesion on the anterior wall of the lower gastric body...
June 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28284884/risk-of-advanced-lesions-at-the-first-follow-up-colonoscopy-after-polypectomy-of-diminutive-versus-small-adenomatous-polyps-of-low-grade-dysplasia
#13
Orly Sneh Arbib, Valentina Zemser, Yaara Leibovici Weissman, Rachel Gingold-Belfer, Alex Vilkin, Sapir Eizenstein, Arnon Cohen, Doron Comaneshter, Shochat Tzipora, Yaron Niv, Yeuda Ringel, David Lieberman, Zohar Levi
BACKGROUND AND AIMS: The current guidelines for surveillance after polypectomy do not distinguish between diminutive (1-5 mm) and small (6-9 mm) polyps with low-grade dysplasia (LGD). We aimed to evaluate the risk for advanced neoplasia on follow-up colonoscopy. METHODS: We retrospectively analyzed 443 patients whose worst finding at index colonoscopy was polypectomy of 1 to 5 or 6 to 9 mm polyps with LGD and those who underwent a follow-up colonoscopy. RESULTS: During a mean follow-up of 32...
March 8, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28252346/lymphangioma-of-the-jejunal-mesentery-and-jejunal-polyps-presenting-as-an-acute-abdomen-in-a-teenager
#14
Jasb Jayasundara, E Perera, M V Chandu de Silva, A A Pathirana
Cystic lymphangioma of the small bowel mesentery is a rare clinical entity, especially after childhood. Medical literature reveals a limited number of such cases presenting as acute abdomen due to bowel obstruction, small bowel volvulus and bleeding into the tumour. We present the management experience of an 18-year-old woman who presented with rapid onset diffuse peritonism and raised inflammatory markers. Computed tomography showed a mass in the small bowel mesentery with suspicion of segmental bowel ischaemia...
March 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28219690/factors-associated-with-shorter-colonoscopy-surveillance-intervals-for-patients-with-low-risk-colorectal-adenomas-and-effects-on-outcome
#15
RANDOMIZED CONTROLLED TRIAL
Joseph C Anderson, John A Baron, Dennis J Ahnen, Elizabeth L Barry, Roberd M Bostick, Carol A Burke, Robert S Bresalier, Timothy R Church, Bernard F Cole, Marcia Cruz-Correa, Adam S Kim, Leila A Mott, Robert S Sandler, Douglas J Robertson
BACKGROUND & AIMS: Endoscopists do not routinely follow guidelines to survey individuals with low-risk adenomas (LRAs; 1-2 small tubular adenomas, < 1 cm) every 5-10 years for colorectal cancer; many recommend shorter surveillance intervals for these individuals. We aimed to identify the reasons that endoscopists recommend shorter surveillance intervals for some individuals with LRAs and determine whether timing affects outcomes at follow-up examinations. METHODS: We collected data from 1560 individuals (45-75 years old) who participated in a prospective chemoprevention trial (of vitamin D and calcium) from 2004 through 2008...
June 2017: Gastroenterology
https://www.readbyqxmd.com/read/28147305/the-heparanase-inhibitor-pg545-attenuates-colon-cancer-initiation-and-growth-associating-with-increased-p21-expression
#16
Preeti Singh, Alexandra Blatt, Sari Feld, Yaniv Zohar, Esraa Saadi, Liza Barki-Harrington, Edward Hammond, Neta Ilan, Israel Vlodavsky, Yehuda Chowers, Elizabeth Half
Heparanase activity is highly implicated in cellular invasion and tumor metastasis, a consequence of cleavage of heparan sulfate and remodeling of the extracellular matrix underlying epithelial and endothelial cells. Heparanase expression is rare in normal epithelia, but is often induced in tumors, associated with increased tumor metastasis and poor prognosis. In addition, heparanase induction promotes tumor growth, but the molecular mechanism that underlines tumor expansion by heparanase is still incompletely understood...
March 2017: Neoplasia: An International Journal for Oncology Research
https://www.readbyqxmd.com/read/28104992/ileo-ileal-intussusception-caused-by-lymphangioma-of-the-small-bowel-treated-by-single-incision-laparoscopic-assisted-ileal-resection
#17
Atsushi Kohga, Akihiro Kawabe, Yuto Hasegawa, Kiyoshige Yajima, Takuya Okumura, Kimihiro Yamashita, Jun Isogaki, Kenji Suzuki, Akira Komiyama
Intraabdominal lymphangiomas are uncommon; additionally, those affecting the gastrointestinal tract are rare and account for less than 1% of cases. Intussusception caused by a cystic lymphangioma of the small bowel is extremely rare. The patient was a 20-year-old woman who visited our emergency room with a complaint of abdominal pain. A computed tomography image revealed ileo-ileal intussusception with a leading hypovascular mass measuring 1 cm in a diameter. Single-incision laparoscopic-assisted ileal resection was performed...
January 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28079233/suspected-blood-indicator-in-capsule-endoscopy-a-valuable-tool-for-gastrointestinal-bleeding-diagnosis
#18
Pedro Boal Carvalho, Joana Magalhães, Francisca Dias DE Castro, Sara Monteiro, Bruno Rosa, Maria João Moreira, José Cotter
BACKGROUND: Small bowel bleeding is a leading indication for small bowel capsule endoscopy. The Suspected Blood Indicator (SBI) is a software feature directed to automatically detect bleeding lesions during small bowel capsule endoscopy. OBJECTIVE: - We aimed to assess SBI diagnostic accuracy for small bowel haemorrhage or potentially bleeding lesions during small bowel capsule endoscopy for small bowel bleeding. Methods - Single-centre retrospective study including 281 consecutive small bowel capsule endoscopy performed for small bowel bleeding during 6 years...
January 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28035250/from-traditional-serrated-adenoma-to-tubulovillous-adenoma-and-beyond
#19
REVIEW
Sangeetha N Kalimuthu, Adeline Chelliah, Runjan Chetty
It is well established that colorectal cancer develops from a series of precursor epithelial polyps, including tubular adenomas, villous/tubulovillous adenomas (VA/TVA), sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA). Of these, TSAs are least common and account for only 5% of all serrated polyps. TSAs are characterised by the presence of a "pinecone-like" architecture, granular eosinophilic cytoplasm, luminal serrations, ectopic crypt foci (ECF) and elongated, pencillate nuclei. However, the distinct slit-like luminal serrations, reminiscent of small bowel mucosa, appear to be the most unique and reproducible feature to distinguish TSAs from other polyps...
December 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28024986/natural-history-of-diminutive-and-small-colorectal-polyps-a%C3%A2-systematic-literature-review
#20
REVIEW
Jasper L A Vleugels, Yark Hazewinkel, Paul Fockens, Evelien Dekker
BACKGROUND AND AIMS: Diminutive (1-5 mm) and small (6-9 mm) polyps comprise 90% of detected lesions during colonoscopy and rarely contain advanced histology or colorectal cancer (CRC). Routine removal of these lesions results in a significant burden to colonoscopy programs. At the same time, the risk for progression of these polyps to CRC is unclear. We performed a systematic review to explore the natural history of diminutive and small colorectal polyps. METHODS: We searched MEDLINE and EMBASE for studies investigating the natural history of colorectal polyps...
December 23, 2016: Gastrointestinal Endoscopy
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