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https://www.readbyqxmd.com/read/27689205/non-gastric-gastrointestinal-xanthomas-case-series-and-literature-review
#1
Cristina Díaz Del Arco, Ángel Álvarez Sánchez, M Jesús Fernández Aceñero
Gastrointestinal xanthomas are infrequent non-neoplastic lesions characterized by the accumulation of foam cells in the lamina propria. They are commonly seen in association with dyslipidemia, chemotherapy or radiotherapy, and infections in immunosuppressed patients. However, no clear connection to hyperlipidemia has been found. They occur more frequently in the stomach, and are very rare in the small bowel and esophagus. We identified all cases of non-gastric xanthoma or xanthomatosis reported in the English literature by searching the PubMed database and retrospectively reviewed the clinical, endoscopic, and histopathologic features of the 11 cases of non-gastric gastrointestinal xanthomas diagnosed in our hospital...
September 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/27639097/wireless-capsule-enteroscopy-in-healthy-volunteers
#2
Ilja Tachecí, Petr Bradna, Tomáš Douda, Drahomíra Baštecká, Marcela Kopáčová, Stanislav Rejchrt, Martin Lutonský, Tomáš Soukup, Jan Bureš
INTRODUCTION: The aim of our prospective study was to define endoscopy appearance of the small bowel in healthy volunteers. METHOD: Forty-two healthy volunteers underwent wireless capsule endoscopy, clinical investigation, laboratory tests, and completed a health-status questionnaire. All subjects were available for a 36-month clinical follow-up. RESULTS: Eleven subjects (26%) had fully normal endoscopy findings. Remaining 31 persons (74%), being asymptomatic, with normal laboratory results, had some minor findings at wireless capsule endoscopy...
September 8, 2016: Acta Medica (Hradec Králové)
https://www.readbyqxmd.com/read/27629953/newly-developed-endoscopic-treatment-for-small-bowel-polyps-cold-snare-polypectomy
#3
Junichi Sato, Yoshiki Hirooka, Osamu Watanabe, Masanao Nakamura, Takeshi Yamamura, Kohei Funasaka, Eizaburo Ohno, Hiroki Kawashima, Ryoji Miyahara, Hidemi Goto
A 72-year-old man with the history of small bowel carcinoma was diagnosed to have a sessile polyp in the jejunum during a follow-up examination. We performed double-balloon endoscopy and removed the polyp by means of cold snare polypectomy. The follow-up endoscopy showed no residual lesion. Cold snare polypectomy has been established as a safe and effective method for the endoscopic treatment of colonic polyps with a low risk of causing electrocautery burns and perforation. However, this technique has not yet been applied for small bowel lesions...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27574615/cronkhite-canada-syndrome-polyps-infiltrated-with-igg4-positive-plasma-cells
#4
Ru-Ying Fan, Xiao-Wei Wang, Li-Jun Xue, Ran An, Jian-Qiu Sheng
Cronkhite-Canada syndrome (CCS) is a rare but serious protein-losing enteropathy, but little is known about the mechanism. Further more, misdiagnosis is common due to non-familiarity of its clinical manifestation. A 40-year-old male patient was admitted to our hospital because of diarrhea and hypogeusia associated with weight loss for 4 mo. On physical examination, skin pigmentation, dystrophic nail changes and alopecia were noted. He had no alike family history. Laboratory results revealed low levels of serum albumin (30...
August 16, 2016: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/27477802/hamartomatous-polyps-a-clinical-and-molecular-genetic-study
#5
Anne Marie Jelsig
Hamartomatous polyps (HPs) in the gastrointestinal (GI) tract are rare compared to other types of GI polyps, yet they are the most common type of polyp in children. The symptoms are usually rectal bleeding, abdominal pain, obstipation, anaemia, and/or small bowel obstruction. The polyps are typically removed concurrently with endoscopy when located in the colon, rectum, or stomach, whereas polyps in the small bowel are removed during push-enteroscopy, device-assisted enteroscopy, or by surgery. HPs can be classified as juvenile polyps or Peutz-Jeghers polyps based on their histopathological appearance...
August 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27466165/sequential-crohn-s-ileitis-ileosigmoidal-fistula-segmental-sigmoid-polyposis-and-sigmoid-stricture-the-natural-history
#6
Burton I Korelitz, Vivek Kesar, Raja Taunk, Judy Schneider
BACKGROUND: We have previously recognized segmental sigmoid polyps as an indicator of a fistula from Crohn's ileitis to the sigmoid or the proximal rectum. In the course of this study, we realized that many patients with this fistula had no sigmoid polyps, but the sigmoid was the site of marked inflammation and early or late stricture formation. Furthermore, in some patients with a stricture, the fistula was not recognized until the surgeon (or the pathologist) dissected an inflammatory peri-ileal and/or a perisigmoidal mass...
July 25, 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27404294/small-bowel-surveillance-in-patients-with-peutz-jeghers-syndrome-comparing-magnetic-resonance-enteroclysis-and-double-balloon-enteroscopy
#7
Anne Goverde, Susanne E Korsse, Anja Wagner, Monique E van Leerdam, Nanda C Krak, Jaap Stoker, Henk R van Buuren, Robert M W Hofstra, Marco J Bruno, Pieter Dewint, Evelien Dekker, Manon C W Spaander
BACKGROUND AND STUDY AIMS: Small-bowel surveillance with polypectomy of polyps ≥15 mm prevents complications in patients with Peutz-Jeghers syndrome (PJS). We aimed to compare magnetic resonance enteroclysis (MRE) and double balloon enteroscopy (DBE) for diagnostic yield of these polyps and for patient preference. MATERIALS AND METHODS: PJS patients prospectively underwent MRE followed by proximal DBE within 20 weeks. Endoscopists were blinded to the MRE results...
July 11, 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27326320/genetic-risks-and-familial-associations-of-small-bowel-carcinoma
#8
REVIEW
Santosh Shenoy
Adenocarcinoma of small intestines (SBA) is a relatively rare malignancy with poor outcomes due to delayed diagnosis. Fifty percent of patients have metastases on presentation and therefore early detection and treatment offers the best long term outcomes. Certain genetic polyposis syndromes and familial diseases are associated with increased risks for SBA. These include familial adenomatous polyposis (FAP), Lynch syndromes (LS), Juvenile polyposis syndrome, Peutz-Jeghers syndrome, Crohn's disease (CD) and celiac disease...
June 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/27224637/failed-intussusception-reduction-in-children-correlation-between-radiologic-surgical-and-pathologic-findings
#9
Aikaterini Ntoulia, Sasha J Tharakan, Janet R Reid, Soroosh Mahboubi
OBJECTIVE: The objective of this study was to identify causes of irreducible intussusception after contrast enema and to correlate imaging findings with surgical and histopathologic findings. MATERIALS AND METHODS: Between 2005 and 2013, a total of 543 children underwent reduction of intussusception with the use of an enema technique (hereafter referred to as "enema reduction"). The medical records of 72 children (56 boys [mean age, 24.8 months; range, 3.8 months to 10...
August 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27217901/-peutz-jeghers-syndrome-manifested-as-massive-mel%C3%A3-na-at-chu-jra-madagascar-hospital-a-case-report
#10
Andrianimaro Florelia Martinetti, Rasoanaivo Mamy Andriantsoa, Rajaonera Tovohery Andriambelo, Rakotoarison Ratsaraharimanana Cathérine Nicole, Raveloson Nasolotsiry Enintsoa
Peutz-Jeghers syndrome (SPJ) is characterized by intestinal hamartomatous polyps in association with mucocutaneous lentiginosis. Patients are exposed to mechanical and bleeding complications. It is a cancer predisposition syndrome. Our study highlights the diagnostic criteria for Peutz-Jeghers syndrome (SPJ), the complications and the therapeutic progresses in patient care. We report the case of a 32-year-old male presenting with a massive melaena. It was hospitalized in the surgical intensive care unit with hypovolemic shock difficult to control...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27157712/inflammatory-fibroid-polyp-of-the-gastrointestinal-tract-10-years-of-experience-at-the-instituto-nacional-de-ciencias-m%C3%A3-dicas-y-nutrici%C3%A3-n-salvador-zubir%C3%A3-n
#11
A F Romano-Munive, R Barreto-Zuñiga, J A Rumoroso-García, P Ramos-Martínez
BACKGROUND: Inflammatory fibroid polyp (lFP) is a rare, benign, and solitary neoplasm predominantly located in the gastric antrum and small bowel. Its clinical symptoms are heterogeneous and essentially depend on the location and size of the tumor. Definitive diagnosis is made through histopathology and this pathology has excellent long-term prognosis. AIM: To identify the cases of IFP seen at the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán over a 10-year period...
July 2016: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/27117717/rare-presentation-of-small-bowel-intussusception-in-childhood
#12
Chung-Yan Grace Chan, Pui-Ki Jane Tsang, Ping-Yung Chu, Yiu-Chung Wong
Small bowel intussusception complicated simultaneously by volvulus in an older child is rare but clinically significant, necessitating urgent operative management. We report a local case of jejuno-jejunal intussusception complicated by volvulus and bowel infarction in a 9-year-old Chinese girl, with diagnosis made on preoperative computed tomography and confirmed at laparotomy. An intestinal polyp as the lead point for intussusception was identified operatively.
July 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27112247/capsule-endoscopy-with-retention-of-the-capsule-in-a-duodenal-diverticulum-a-case-report
#13
Siho Kim, Sang Su Bae, Hyung Jun Chu, Ji Hwan Park, Gyu Cheon Kyung, Hyo Dong An, Keun Kim, Eun Gyu Gang
Capsule endoscopy is being increasingly recognized as a gold standard for diagnosing small bowel disease, but along with the increased usage, capsule retention is being reported more frequently. We report a case of capsule endoscopy retention in a diverticulum of the duodenal proximal third portion, which we treated by esophagogastroduodenoscopy. A 69-year-old male visited hospital with hematochezia. He had hypertension and dyslipidemia for several years, and was taking aspirin to prevent heart disease. CT and colonoscopy revealed a diverticulum in the third portion of the duodenum, rectal polyps, and internal hemorrhoids...
April 25, 2016: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/27104828/dna-methylation-and-mutation-of-small-colonic-neoplasms-in-ulcerative-colitis-and-crohn-s-colitis-implications-for-surveillance
#14
David H Johnson, William R Taylor, Mohammed M Aboelsoud, Patrick H Foote, Tracy C Yab, Xiaoming Cao, Thomas C Smyrk, Edward V Loftus, Douglas W Mahoney, David A Ahlquist, John B Kisiel
BACKGROUND: Stool DNA testing in patients with inflammatory bowel disease (IBD) may detect colorectal cancer and advanced precancers with high sensitivity; less is known about the presence of DNA markers in small IBD lesions, their association with metachronous neoplasia, or contribution to stool test positivity. METHODS: At a single center in 2 blinded phases, we assayed methylated bone morphogenic protein 3, methylated N-Myc downstream-regulated gene 4, and mutant KRAS in DNA extracted from paraffin-embedded benign lesions, and matched control tissues of patients with IBD, who were followed for subsequent colorectal dysplasia...
July 2016: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/27086004/small-bowel-neoplasms-and-polyps
#15
REVIEW
Kamron Pourmand, Steven H Itzkowitz
The small intestine is a relatively privileged organ that only rarely develops malignant or even benign tumors. Given this rarity, the relative inaccessibility of the organ during routine endoscopic procedures, and the typical absence or nonspecific nature of clinical manifestations, these tumors often go undiagnosed. Treatment and prognosis are tailored to each histological subtype of tumor. This chapter will discuss the epidemiology, presentation, diagnostics, and management for the most common small bowel tumors, and will highlight the importance of recognizing patients at higher risk of small bowel neoplasia...
May 2016: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/27061809/usefulness-of-cold-polypectomy-for-small-bowel-polyps-in-peutz-jeghers-syndrome
#16
LETTER
Rinzaburo Matsuura, Masanao Nakamura, Hidemi Goto
No abstract text is available yet for this article.
July 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27017108/insertion-water-exchange-increases-right-colon-adenoma-and-hyperplastic-polyp-detection-rates-during-withdrawal
#17
Sergio Cadoni, Přemysl Falt, Stefano Sanna, Mariangela Argiolas, Viviana Fanari, Paolo Gallittu, Mauro Liggi, Donatella Mura, Maria L Porcedda, Vit Smajstrla, Matteo Erriu, Felix W Leung
BACKGROUND: Single site studies in male Veterans in the U.S. reported increased detection of presumptive cancer precursors (adenomas, hyperplastic polyps) in the proximal colon (cecum-splenic flexure) by water exchange. AIMS: Assess the reproducibility of the observation. METHODS: Analysis of secondary outcomes collected prospectively in 3 similarly designed randomized controlled trials using water exchange, water immersion and insufflation (air or carbon dioxide)...
June 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/26979979/disease-pattern-in-danish-patients-with-peutz-jeghers-syndrome
#18
A M Jelsig, N Qvist, L Sunde, K Brusgaard, Tvo Hansen, F P Wikman, C B Nielsen, I K Nielsen, A M Gerdes, A Bojesen, L B Ousager
PURPOSE: In this paper, we aimed to collect genetic and medical information on all Danish patients with Peutz-Jeghers syndrome (PJS), in order to contribute to the knowledge of phenotype and genotype. Peutz-Jeghers syndrome is a hereditary syndrome characterized by multiple hamartomatous polyps in the GI tract, mucocutaneous pigmentations, and an increased risk of cancer in the GI tract and at extraintestinal sites. Over 90 % of patients harbour a pathogenic mutation in STK11. METHODS: Based on the Danish Pathology Data Bank, the Danish National Patient Register, as well as information from relevant departments at Danish hospitals, we identified patients and collected clinical and genetic information...
May 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/26962305/multidetector-ct-enterography-versus-double-balloon-enteroscopy-comparison-of-the-diagnostic-value-for-patients-with-suspected-small-bowel-diseases
#19
Jingjing Wang, Qiaozhen Guo, Jianping Zhao, Mei Liu, Guangquan Liao, Nianjun Chen, Dean Tian, Xiaoli Wu
Aim. To compare the diagnostic value of multidetector CT enterography (MDCTE) and double-balloon enteroscopy (DBE) for patients with suspected small bowel diseases. Methods. From January 2009 to January 2014, 190 patients with suspected small bowel diseases were examined with MDCTE and DBE. The characteristics of the patients, detection rates, diagnostic yields, sensitivity, specificity, positive predictive value, and negative predictive value were described and analyzed. Results. The overall detection rates of DBE and MDCTE were 92...
2016: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/26941798/cronkhite-canada-syndrome-a-rare-cause-of-chronic-diarrhoea-in-a-young-man
#20
Dhrubajyoti Bandyopadhyay, Adrija Hajra, Vijayan Ganesan, Suvrendu Sankar Kar, Debarati Bhar, Manas Layek, Sabyasachi Mukhopadhyay, Cankatika Choudhury, Vivek Choudhary, Prasun Banerjee
A young Indian man presented with nine-month history of chronic diarrhea, occasionally mixed with blood and intermittent colicky abdominal pain. He also complained of generalized body swelling for the last three months. On examination, he had diffuse hyperpigmentation of the skin and dystrophic nail changes. Upper and lower gastrointestinal endoscopy revealed multiple sessile polyps in the stomach, small bowel, and colon and rectum. Biopsy of polyps showed adenomatous changes with stromal edema and dilated glands...
2016: Case Reports in Medicine
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