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https://www.readbyqxmd.com/read/29240374/case-study-case-studies-in-cystinuria
#1
David S Goldfarb, Michael Grasso
The diagnosis and treatment of patients with rare inherited metabolic disorders associated with recurrent and often obstructive kidney stones are important to the prevention of chronic kidney disease or end stage renal disease. Two case studies in this article describe the diagnosis and management of cystinuria, the most common rare kidney stone disorder.
March 2017: Urologic Nursing
https://www.readbyqxmd.com/read/29235239/familial-risks-in-urolithiasis-in-the-population-of-sweden
#2
Kari Hemminki, Otto Hemminki, Asta Försti, Kristina Sundquist, Jan Sundquist, Xinjun Li
OBJECTIVES: To assess detailed familial risks for medically diagnosed urolithiasis (UL, urinary tract stone disease) based on nationwide hospital and population records. SUBJECTS/PATIENTS AND METHODS: Subjects were identified from the Swedish Multigeneration Register in which 211,718 UL patients. Standardized incidence ratios (SIRs) were calculated by comparison to individuals without a family history of UL. RESULTS: The highest familial SIRs were invariably found for the same (concordant) type of UL: 2...
December 13, 2017: BJU International
https://www.readbyqxmd.com/read/29234532/bilateral-same-session-ureterorenoscopy-a-feasible-approach-to-treat-pan-urinary-stone-disease
#3
Bora Özveren, Murat Tugrul Eren, Hakan Özveri, Uğur Altuğ, Ahmet Şahin
Objectives: To assess treatment effectiveness and safety of bilateral same-session ureterorenoscopy (BSSU) for the management of stone disease involving the entire urinary system. Patients and methods: We reviewed the records of 64 patients who underwent BSSU for the treatment of bilateral ureteric and/or kidney stones. Size, number, location per side, and the total burden of stones were recorded. Data on stenting, lithotripsy, and stone retrieval, and details of hospital stay and operation times were investigated...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29204238/crossed-fused-renal-ectopia-case-report-and-review-of-the-literature
#4
Anna Mudoni, Francesco Caccetta, Maurizio Caroppo, Fernando Musio, Antonella Accogli, Maria Dolores Zacheo, Maria Domenica Burzo, Vitale Nuzzo
Crossed fused renal ectopia is a rare congenital anomaly, and is mostly detected incidentally. A 45-year-old man, during investigation for recurrent abdominal pain, was found to have an empty left renal fossa and right crossed renal ectopia with fusion on ultrasonography. In the present case, there were no abnormalities and/or alteration of the renal function. Abdominal tomography scan with contrast medium confirmed the diagnosis. Ectopic kidney is often associated with other abnormal situations such as agenesis, vascular malformation, incontinence, a palpable abdominal mass, urinary tract infection, high incidence of stone formation, and genital anomalies...
December 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/29202723/changes-in-urinary-risk-profile-after-short-term-low-sodium-and-low-calcium-diet-in-recurrent-swiss-kidney-stone-formers
#5
Harald Seeger, Andrea Kaelin, Pietro M Ferraro, Damian Weber, Philippe Jaeger, Patrice Ambuehl, William G Robertson, Robert Unwin, Carsten A Wagner, Nilufar Mohebbi
BACKGROUND: Kidney stone disease is common in industrialized countries. Recently, it has attracted growing attention, because of its significant association with adverse renal outcomes, including end stage renal disease. Calcium-containing kidney stones are frequent with high recurrence rates. While hypercalciuria is a well-known risk factor, restricted intake of animal protein and sodium, combined with normal dietary calcium, has been shown to be more effective in stone prevention compared with a low-calcium diet...
December 4, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29188308/ureteroscopy-from-the-recent-past-to-the-near-future
#6
REVIEW
José Manuel Reis Santos
Stone surgery is one of oldest surgical practices undertaken by man. Hippocrates refused to let his followers "cut for the stone" and it was only in February 1980, when the first human trial of shock wave therapy on a renal stone was performed with success that a new era in minimally invasive treatment (surgery) for stones was opened up and this condemnation was finally resolved in the Hippocratic Oath. Endoscopy, using natural orifices, supported by anaesthesia, incremented by technology and with access to all points along the urinary tract, began by competing with ESWL, but is now the treatment of choice in most cases...
November 29, 2017: Urolithiasis
https://www.readbyqxmd.com/read/29179563/clinical-outcomes-for-cystinuria-patients-with-unilateral-versus-bilateral-cystine-stone-disease
#7
Manint Usawachintachit, Benjamin Sherer, Matthew Hudnall, David T Tzou, Kazumi Taguchi, Ryan S Hsi, Marshall Stoller, Thomas Chi
<b>Introduction</b>: Cystinuria is a genetic disorder marked by elevated urinary cystine excretion and recurrent cystine nephrolithiasis. Interestingly, despite seemingly similar contralateral renal anatomy, a subset of cystinuric patients consistently form stones in only one kidney. The aim of this study is to evaluate clinical outcomes in unilateral versus bilateral cystine stone formers. <b>Methods</b>: We performed a retrospective case-control study of cystinuric patients evaluated and treated at the University of California, San Francisco between 1994 and 2015 and categorized patients as either unilateral or bilateral stone formers...
November 27, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29098195/subcapsular-splenic-urinoma-and-splenorenal-fistula-a-new-complication-of-percutaneous-nephrolithotomy
#8
Eugene B Cone, Ghalib Jibara, Daniel Wollin, Glenn M Preminger
Background: Splenic urinoma has not been previously reported as a complication of percutaneous nephrolithotomy (PNL). Case Presentation: A 46-year-old Caucasian male underwent PNL for two large left renal stones. Surgery was performed in prone split-leg position, with access obtained through combined fluoroscopic guidance and direct ureteroscopic observation of the targeted calix. The tract was dilated to 30F using a pressure balloon, and complete clearance of stones was obtained through a combination of rigid and flexible nephroscopy, as well as antegrade ureteroscopy...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29073769/retrospective-cost-analysis-of-a-single-center-reusable-flexible-ureterorenoscopy-program-a-comparative-cost-simulation-of-disposable-furs-as-an-alternative
#9
Tomasz Ozimek, Michael H Schneider, Marie C Hupe, Judith R Wiessmeyer, Jens Cordes, Piotr L Chlosta, Axel S Merseburger, Mario Wolfgang Kramer
OBJECTIVE: The increasing number of flexible ureterorenoscopy (fURS) procedures, the fragility of devices, and their growing maintenance and repair costs represent a substantial burden for urologic departments. Disposable single-use fURS devices offer many advantages over reusable fURS. Among them, the LithoVue™ model shows the best clinical utility. In our study, we assessed the economic aspects of reusable fURS application compared with the potential costs and benefits of single-use fURS (LithoVue™)...
November 17, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29061541/personalized-intervention-in-monogenic-stone-formers
#10
REVIEW
Lucas J Policastro, Subodh J Saggi, David S Goldfarb, Jeffrey P Weiss
PURPOSE: The treatment of a first-time renal stone episode consists of acute management followed by medical efforts to prevent stone recurrence. Though nephrolithiasis is roughly 50% heritable, the presence of a family history usually does not affect treatment, as most stone disease is regarded as polygenic, i.e. not attributable to a single gene. Recently, new evidence has suggested that single mutations could be responsible for a larger proportion of renal stones than expected. This intriguing possibility holds the potential to change the management paradigm in stone prevention from metabolically-directed therapy to more specific approaches informed by genetic screening and testing...
October 20, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29038707/prevalence-of-idiopathic-hypercalciuria-in-children-with-urinary-system-related-symptoms-attending-a-pediatric-hospital-in-bandar-abbas-in-2014
#11
Maryam Esteghamati, Kambiz Ghasemi, Marie Nami
BACKGROUND: Idiopathic hypercalciuria is a group of diseases which can be manifested with urinary symptoms. Its importance is due to high prevalence, recurrent infections, and stone formations which are often asymptomatic. OBJECTIVE: The objective of this study was to determine the prevalence of idiopathic hypercalciuria in children with urinary system related symptoms in Bandar Abbas in 2014. METHODS: This descriptive cross-sectional study was done in 2014 in a children's hospital in Bandar Abbas (southern Iran) on 321 children who were between 2 months to 14 years old...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29025381/adenovirus-infection-as-a-cause-of-fever-of-unknown-origin-and-allograft-dysfunction-in-a-kidney-transplant-recipient
#12
Michelle Saliba, Hala Kfoury Assouf, Souodod Abbas, Pierre Abi Hanna, Gaby Kamel, Antoine Barbari
With the recent introduction of more potent modern immunosuppressive regimens in solid-organ transplant, new types of viral infections such as adenovirus are emerging as a potential cause for graft dysfunction and loss. We report a case of 41-year-old male patient with end-stage renal disease from recurrent kidney stones who underwent kidney transplant from a deceased 12-year-old female donor. He developed adenoviral infection with acute cystitis, microscopic hematuria, and necrotizing interstitial nephritis associated with graft dysfunction within the first month of the postoperative period...
October 12, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28981230/-diagnosis-and-treatment-of-nephrolithiasis-and-prevention-of-recurrences
#13
I Simon, F Legrand, J M Des Grottes, F Cotton, J Nortier, T Roumeguère
despite fluctuations, the prevalence of nephrolithiasis has significantly increased during the last decades in industrialized nations worldwide (1 to 15 %), which has a significant impact on the cost of healthcare. This increased prevalence is mainly explained by diet modifications. Environmental, metabolic and genetic factors may also influence the formation of kidney stones. As a consequence, the medical management of this disease is preferentially multidisciplinary and involves urologists, nephrologists, radiologists, biologists and dietitians...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28980082/accuracy-of-daily-fluid-intake-measurements-using-a-smart-water-bottle
#14
Michael S Borofsky, Casey A Dauw, Nadya York, Colin Terry, James E Lingeman
High fluid intake is an effective preventative strategy against recurrent kidney stones but is known to be challenging to achieve. Recently, a smart water bottle (Hidrate Spark™, Minneapolis, MN) was developed as a non-invasive fluid intake monitoring system. This device could help patients who form stones from low urine volume achieve sustainable improvements in hydration, but has yet to be validated in a clinical setting. Hidrate Spark™ uses capacitive touch sensing via an internal sensor. It calculates volume measurements by detecting changes in water level and sends data wirelessly to users' smartphones through an application...
October 4, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28970593/occupations-and-the-risk-of-bladder-cancer-in-yazd-province-a-case-control-study
#15
Fatemeh Farzaneh, Amir Houshang Mehrparvar, Mohammad Hassan Lotfi
BACKGROUND: Bladder cancer is the most common cancer of the urinary tract, with known occupational causes. The most effective way to prevent occupational cancers of the urinary tract is to prevent exposure to known carcinogens. OBJECTIVE: To examine the relationship between occupation and the risk of bladder cancer. METHODS: This case-control study was performed on 200 patients with bladder cancer and 200 healthy individuals in Yazd. Data were collected using a researcher-made questionnaire and based on interviews with patients and controls...
October 2017: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28969396/epidemiologic-study-of-urolithiasis-in-seven-countries-of-south-eastern-europe-s-e-g-u-r-1-study
#16
Andreas Karagiannis, Andreas Skolarikos, Emanuel Alexandrescu, Dragoslav Basic, Petrisor Geavlete, Alessandro Maletta, A Yaser Muslumanoglu, Athanasios Papatsoris, Kremena Petkova, Skender Saidi, Aleksandar Skakic, Iliya Saltirov, Kemal Sarica, Sotir Stavridis, Omer Yilmaz, Alberto Trinchieri
OBJECTIVE: To investigate some epidemiological aspects of kidney stones in the South- Eastern European area. MATERIALS AND METHODS: From September 2015 to December 2015, 538 consecutive patients were treated and evaluated for reno-ureteral stones in eight departments in Bulgaria, Greece, Italy, FYR Macedonia, Romania, Serbia and Turkey. RESULTS: The age of onset was lower in Turkey and higher in Italy. The rate of recurrent patients was higher in Romania and Serbia, while first renal stone formers were more frequent in Italy...
October 3, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28966756/preventive-kidney-stones-continue-medical-education
#17
REVIEW
Farahnak Assadi, Mastaneh Moghtaderi
Nephrolithiasis is a common health problem across the globe with a prevalence of 15%-20%. Idiopathic hypercalciuria is the most common cause of nephrolithiasis, and calcium oxalate stones are the most common type of stones in idiopathic hypercalciuric patients. Calcium phosphate stones are frequently associated with other diseases such as renal tubular acidosis type 1, urinary tract infections, and hyperparathyroidism. Compared with flat abdominal film and renal sonography, a noncontrast helical computed tomography scan of the abdomen is the diagnostic procedure of choice for detection of small and radiolucent kidney stones with sensitivity and specificity of nearly 100%...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28952685/-laparoscopic-pyelolithotomy-and-its-role-in-modern-surgery-of-nephrolithiasis
#18
P V Glybochko, Yu G Alyaev, L M Rapoport, M E Enikeev, D G Tsarichenko, E V Shpot, D O Korolev, A A Vorobyev, D V Enikeev
AIM: To determine the place of laparoscopic pyelolithotomy in surgical management of nephrolithiasis. MATERIALS AND METHODS: We analyzed 16 laparoscopic pyelolithotomies performed in our clinic over the last few years for large and stag-horn stones of anomalous kidneys (n=8), the "giant" (>30-40 cc) monolithic stones of the large extrarenal pelvis (n=3), multiple stones of PCS with the stone burden of more or equal 40 cm (n=2) and large recurrent (after PCNL) kidney stones in patients at risk of bacteriotoxic complications of percutaneous nephroscopy (n=3)...
September 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28951890/the-induction-of-oxalate-metabolism-in-vivo-is-more-effective-with-functional-microbial-communities-than-with-functional-microbial-species
#19
Aaron W Miller, Colin Dale, M Denise Dearing
For mammals, oxalate enters the body through the diet or is endogenously produced by the liver; it is removed by microbial oxalate metabolism in the gut and/or excretion in feces or urine. Deficiencies in any one of the these pathways can lead to complications, such as calcium oxalate urinary stones. While considerable research has been conducted on individual oxalate-degrading bacterial isolates, interactions between oxalate and the gut microbiota as a whole are unknown. We examined the reduction in oxalate excretion in a rat model following oral administration of fecal microbes from a mammalian herbivore adapted to a high oxalate diet or to fecal transplants consisting of two different formulations of mixed oxalate-degrading isolates...
September 2017: MSystems
https://www.readbyqxmd.com/read/28943803/primary-hyperoxaluria-detected-by-bone-marrow-biopsy-case-report
#20
F Nachite, M Dref, A Fakhri, H Rais
BACKGROUND: Primary hyperoxaluria is a rare disease with an estimated prevalence of 1 to 3 cases per million. It is due to a hepatic enzyme deficiency responsible for an endogenous overproduction of oxalate. Oxalate crystals commonly deposit in the kidney and more rarely in bone marrow. The literature has reported, to the best of our knowledge, only two cases of hyperoxaluria diagnosed by bone marrow biopsy and our case is the only one that does not show radiological bone lesions. CASE PRESENTATION: A young 22 year old chronic hemodialysis patient with nephrocalcinosis...
2017: BMC Clinical Pathology
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