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kidney stone recurrence

Ines van Dooren, Kenn Foubert, Sebastiaan Bijttebier, Mart Theunis, Stefaniya Velichkova, Magda Claeys, Luc Pieters, Vassiliki Exarchou, Sandra Apers
Stone diseases present a major health problem in the Western society, since both urinary and biliary stones occur with a relatively high prevalence of 10-12 % and 10-20 %, respectively, and demonstrate a high recurrence rate. At the moment treatment is mainly based on interventional procedures, or prophylactic and dissolution therapy. However, many of the current drugs cause severe side effects, and therefore, there is an increasing interest in natural medicines. At the moment no registered herbal medicinal products are available for treatment of gallstones...
October 24, 2016: Planta Medica
David I Chu, Gregory E Tasian, Lawrence Copelovitch
Pediatric stone disease is increasing in incidence and healthcare costs. With more years at-risk for stone recurrence during their lifetimes, children with nephrolithiasis constitute a high-risk patient population that requires focused intervention through both medical and surgical means. Through high-quality future studies to compare methods of stone prevention and treatment, the burden of stone disease on the youngest members of society may be ameliorated.
June 2016: Current Treatment Options in Pediatrics
Helena Chang, David T Tzou, Manint Usawachintachit, Brian D Duty, Ryan S Hsi, Jonathan D Harper, Mathew D Sorensen, Marshall Stoller, Roger L Sur, Thomas Chi
<b>Objectives</b>: Registry-based clinical research in nephrolithiasis is critical to advancing quality in urinary stone disease management and ultimately reducing stone recurrence. A need exists to develop HIPAA-compliant registries comprised of integrated electronic health record (EHR) data using prospectively defined variables. An EHR-based standardized patient database - The Registry for Stones of the Kidney & Ureter (ReSKU™) was developed and herein we describe our implementation outcomes...
October 19, 2016: Journal of Endourology
Eiko Hasegawa, Naoki Sawa, Junichi Hoshino, Tatsuya Suwabe, Noriko Hayami, Masayuki Yamanouchi, Akinari Sekine, Rikako Hiramatsu, Aya Imafuku, Masahiro Kawada, Yoshifumi Ubara, Tsunao Imamura, Kenmei Takaichi
We herein present a rare case of an autosomal dominant polycystic kidney disease (ADPKD) patient with Caroli's disease, a congenital embryonic biliary tree ductal plate abnormality often associated with autosomal recessive polycystic kidney disease. A 76-year-old woman with ADPKD on hemodialysis was admitted to our hospital with recurrent cholangitis and hepatobiliary stones. Caroli's disease was diagnosed according to typical imaging findings of cystic intrahepatic bile duct dilatation and the central dot sign...
2016: Internal Medicine
Ryan S Hsi, Thomas Sanford, David S Goldfarb, Marshall L Stoller
PURPOSE: Kidney stone prevention relies on the 24-hour urine collection to diagnose metabolic abnormalities and direct dietary and pharmacologic therapy. While its use is guideline-supported for high risk and interested patients, evidence that the test can accurately predict recurrence or treatment response is limited. We sought to critically reassess the role of the 24-hour urine collection in stone prevention. MATERIALS AND METHODS: In addition to a MEDLINE® search to identify controlled studies of dietary and pharmacologic interventions, evidence supporting the AUA and EAU guidelines for metabolic stone prevention were evaluated...
October 13, 2016: Journal of Urology
Karolína Drbalová, Kateřina Herdová, Petr Krejčí, Monika Nývltová, Svatopluk Solař, Lenka Vedralová, Pavel Záruba, David Netuka, Petr Bavor
Multiple Endocrine Neoplasia (MEN) is a condition in which several endocrine organs of an individual are affected by adenoma, hyperplasia and less often carcinoma, either simultaneously or at different stages of life. Two existing syndromes, MEN1 and MEN2 (2A, 2B), in literature is also mentioned MEN4, are associated also with other non-endocrine disorders. MEN1 (Wermer syndrome) affects the pituitary, parathyroid, and pancreatic area. 95 % of patients show very early manifestation of hyperparathyroidism, often before 40 years of age...
2016: Vnitr̆ní Lékar̆ství
Tarik Emre Sener, Goksel Sener, Ozge Cevik, Pinar Eker, Sule Cetinel, Olivier Traxer, Yiloren Tanidir, Cem Akbal
OBJECTIVE: To evaluate the protective effects of melatonin (Mel) on an ethylene glycol-induced nephrolithiasis model in rats. METHODS: Thirty-two Wistar albino rats were divided into 4 groups; control, ethylene glycol (EG), melatonin prevention (Mel+EG+Mel), melatonin treatment (EG+Mel) groups. 0.75% EG was added to drinking water to create nephrolithiasis model. EG group received EG and Mel+EG+Mel group received both EG and melatonin for 8 weeks. In EG+Mel group, EG is given for 8 weeks and melatonin is given for the last 4 weeks of the experiment...
October 4, 2016: Urology
Mangesh V Suryavanshi, Shrikant S Bhute, Swapnil D Jadhav, Manish S Bhatia, Rahul P Gune, Yogesh S Shouche
Hyperoxaluria due to endogenously synthesized and exogenously ingested oxalates is a leading cause of recurrent oxalate stone formations. Even though, humans largely rely on gut microbiota for oxalate homeostasis, hyperoxaluria associated gut microbiota features remain largely unknown. Based on 16S rRNA gene amplicons, targeted metagenomic sequencing of formyl-CoA transferase (frc) gene and qPCR assay, we demonstrate a selective enrichment of Oxalate Metabolizing Bacterial Species (OMBS) in hyperoxaluria condition...
October 6, 2016: Scientific Reports
Hazem Elmansy, Jafar Hussaen, Mostafa Elhilali, Sero Andonian
Patients with pelvic kidneys are at an increased risk of developing ureteropelvic junction obstruction (UPJO) and nephrolithiasis with limited endourologic options. A 54-year-old man with a left pelvic kidney, recurrent nephrolithiasis, and 12 previous ureteroscopies presented with left UPJO and lower pole calyceal stones. After two failed ureteroscopic attempts, an open pyelolithotomy and pyelocystostomy were performed. After 30 months, he continues to be asymptomatic without recurrence of nephrolithiasis...
October 2016: Canadian Journal of Urology
Amisha Mittal, Simran Tandon, Surender Kumar Singla, Chanderdeep Tandon
Kidney stone formation during hyperoxaluric condition is inherently dependent on the interaction between renal epithelial cells and calcium oxalate (CaOx) crystals. Although modern medicine has progressed in terms of removal of these stones, recurrence and persistent side effects restricts their use. Strategies involving plant based agents which could be used as adjunct therapy is an area which needs to be explored. Plant proteins having antilithiatic activity is a hitherto unexplored area and therefore, we conducted a detailed identification and characterization of antilithiatic proteins from Terminalia arjuna (T...
2016: PloS One
Marcelino Rivera, Chris Jaeger, Daniel Yelfimov, Amy Krambeck
OBJECTIVE: To study brushite stone formers (BSF) change in renal function and overall risk of progression to chronic kidney disease (CKD) over time. MATERIALS AND METHODS: A retrospective review of all patients with urolithiasis on stone analysis was performed from 1995-2003. Stones were classified as brushite if they had at least 10% brushite composition on analysis. Patients with a minimum of 6 years clinical follow-up were included in the study. BSF were matched 1:3 to idiopathic calcium oxalate stone formers (CaOxSF) over the same time period...
September 12, 2016: Urology
Dean G Assimos
No abstract text is available yet for this article.
October 2016: Journal of Urology
Miguel Angel Arrabal-Polo, Maria Del Carmen Cano-Garcia, Juan Esteban Huerta-Brunel, Guillermo Hidalgo-Agullo, Luis Roletto-Salmo, Miguel Arrabal-Martín
INTRODUCTION: The aim of this work is to study the density of the renal papillae in stone-forming patients and to determine its usefulness. MATERIALS AND METHODS: This study included a total of 79 patients diagnosed with renal stones and on whom a computed tomography without contrast was performed from June 2014 to May 2015. The patients were divided into two groups: Group 1 (single ep¬isode) included 43 patients, and Group 2 (recurrent episodes) included 36 patients...
September 1, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Omer Kurt, Ibrahim Buldu, Cuneyt Turan, Cenk Murat Yazici
BACKGROUND: Laparoscopic simple nephrectomy is the standard procedure for the removal of non-functioning benign kidney. It can be performed transperitoneally or retroperitoneally. There are several studies comparing the results of transperitoneally or retroperitoneally laparoscopic nephrectomy but there are limited numbers of study comparing results of laparoscopic transperitoneal simple nephrectomy in non-inflammatory and inflammatory non-functioning kidneys. The aim of this study was to compare the results of laparoscopic transperitoneal simple nephrectomy in non-inflammatory and inflammatory non-functioning kidneys...
2016: SpringerPlus
Raymond J Leveillee, Emily Fell Kelly
BACKGROUND: Since the development of the first flexible ureteroscope, in 1964, technological advances in image quality, flexibility, and deflection have led to the development of the first single-use digital flexible ureteroscope, LithoVue™ (Boston Scientific, Marlborough, MA). With respect to reusable fiber-optic and now digital ureteroscopes, there is an initial capital cost of several thousand dollars (USD) as well as, controversy regarding durability, the cost of repairs and the burdensome reprocessing steps of ureteroscopy...
2016: J Endourol Case Rep
Paolo Ria, Antonia Fabris, Alessandra Dalla Gassa, Gianluigi Zaza, Antonio Lupo, Giovanni Gambaro
Medullary sponge kidney (MSK) is a congenital renal disorder. Its association with several developmental abnormalities in other organs hints at the likelihood of some shared step(s) in the embryogenesis of the kidney and other organs. It has been suggested that the REarranged during Transfection (RET) proto-oncogene and the Glial cell line-Derived Neurotrophic Factor (GDNF) gene are defective in patients with MSK, and both RET and GDNF are known to have a role in the development of the central nervous system, heart, and craniofacial skeleton...
August 29, 2016: Urolithiasis
Takahiro Yasui, Atsushi Okada, Shuzo Hamamoto, Ryosuke Ando, Kazumi Taguchi, Keiichi Tozawa, Kenjiro Kohri
Urolithiasis, a complex multifactorial disease, results from interactions between environmental and genetic factors. Epidemiological studies have shown the association of urolithiasis with a number of lifestyle-related diseases, including cardiovascular diseases, hypertension, chronic kidney disease, diabetes and metabolic syndrome. Elucidation of the mechanisms underlying urinary stone formation will enable development of new preventive treatments. The present article reviews the epidemiology, pathophysiology and potential treatment of urolithiasis...
August 18, 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
Gregory E Tasian, Abdo E Kabarriti, Angela Kalmus, Susan L Furth
PURPOSE: Kidney stone disease has become increasingly common during childhood and adolescence; however, the rate of symptomatic kidney stone recurrence for pediatric patients is uncertain. MATERIALS AND METHODS: We performed a retrospective cohort study of patients aged 3-18 years without anatomic abnormalities or genetic causes of nephrolithiasis who presented with a first symptomatic kidney stone between 2008 and 2014. We determined recurrence rates of symptomatic nephrolithiasis, defined as a new kidney stone on ultrasound and/or CT associated with pain and/or vomiting...
August 10, 2016: Journal of Urology
Zhaohui He, Caixia Zhang, Guohua Zeng
OBJECTIVE: To report our experience of minimally invasive percutaneous nephrolithotomy(MPCNL) in managing upper urinary tract calculi complicated with severe spinal deformity. MATERIALS AND METHODS: Between August 2001 to December 2012, 16 upper urinary calculi in 13 patients with severe spinal deformity were treated by MPCNL. Preoperative investigation of the respiratory function, evaluation of anatomy by intravenous uro¬graphy (IVU) and CT scan, and preoperative kidney ultrasonagraphy with simulation of the percutaneous puncture were performed in all patients...
August 10, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Chengquan Ma, Bingxin Lu, ErLin Sun
BACKGROUND: In recent years, bladder stones are increasing in China. However, a giant bladder stone is rarely found nowadays. METHODS: A case of a 54-year-old man who presented with a >9-year history of urinary frequency and urgency and macrohematuria for the past 3 days, was examined by ultrasound scan, kidney-ureter-bladder x-ray, and computed tomography. Then, the patient received a cystolithotomy. RESULTS: His suprapubic area was hard when palpated...
July 2016: Medicine (Baltimore)
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