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Feng Sun, Ruizhe Zhao, Yiyong Zhu, Di Cui, Xiaohai Wang, Bangmin Han, Shengjie Liang, Haitao Liu, Xiaowen Sun, Fujun Zhao, Dongliang Xu, Shujie Xia
Objective To compare intra-arterial chemotherapy combined with intravesical chemotherapy with intravesical chemotherapy alone in the treatment of high-risk non-muscle invasive bladder cancer (HRBC) after thulium laser resection of a bladder tumor (TmLRBT). MATERIALS AND METHODS: From January 2009 to December 2013, 283 patients with HRBC were randomly assigned to the combined group (group A, n = 141) or intravesical chemotherapy-alone group (group B, n = 142) after TmLRBT. Intra-arterial chemotherapy was administered after initial TmLRBT, with 3 courses at 4-week intervals...
April 18, 2017: Cancer Chemotherapy and Pharmacology
Arnaud Pasquer, Filbert Djeudji, Valérie Hervieu, Maud Rabeyrin, Xavier Barth
INTRODUCTION: Bronchogenic cysts are rare abnormalities and a retrorectal presentation is exceptional. Its natural history is not known, but malignant transformation is quite rare. Retrorectal bronchogenic cysts are usually asymptomatic. PRESENTATION OF THE CASE: We present the case of a 36-year-old young man with a past medical history of HIV seropositivity who underwent a procedure to excise a sacral coccyx cyst at another surgical center in February 2009. A histological examination confirmed it was a sacral cyst that was resected in sano...
2016: International Journal of Surgery Case Reports
Héber Salvador de Castro Ribeiro, Orlando Jorge Martins Torres, Márcio Carmona Marques, Paulo Herman, Antonio Nocchi Kalil, Eduardo de Souza Martins Fernandes, Fábio Ferreira de Oliveira, Leonaldson Dos Santos Castro, Rodrigo Hanriot, Suilane Coelho Ribeiro Oliveira, Marcio Fernando Boff, Wilson Luiz da Costa, Roberto de Almeida Gil, Tulio Eduardo Flesch Pfiffer, Fabio Ferrari Makdissi, Manoel de Souza Rocha, Paulo Cezar Galvão do Amaral, Leonardo Atem Gonçalves de Araújo Costa, Tomas A Aloia
BACKGROUND: Liver metastases of colorectal cancer are frequent and potentially fatal event in the evolution of patients. AIM: In the second module of this consensus, management of resectable liver metastases was discussed. METHOD: Concept of synchronous and metachronous metastases was determined, and both scenarius were discussed separately according its prognostic and therapeutic peculiarities. RESULTS: Special attention was given to the missing metastases due to systemic preoperative treatment response, with emphasis in strategies to avoid its reccurrence and how to manage disappeared lesions...
March 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
Ming Bai, Xia Chen, Y I Ba
The CXCL10/CXCR3 axis of inflammatory mediators is one of the most important groups of chemokine axes, which has been proven to be a lymphocyte-associated metastasis mediator in several tumors. The term inflammatory adhesions refers to tumors found to be attached to the surrouding tissues during surgery, although no cancer cell infiltration is later identified on pathological examination. The aim of the present study was to investigate the clinical characteristics of stage II colorectal cancer (CRC) and determine the correlation between the CXCL10/CXCR3 axis, inflammatory adhesions and prognosis...
January 2016: Molecular and Clinical Oncology
Ján Baumgartner, Mária Šimaljaková, Pavel Babál
Angiokeratomas are rare vascular mucocutaneous lesions characterized by small-vessel ectasias in the upper dermis with reactive epidermal changes. Angiokeratoma circumscriptum (AC) is the rarest among the five types in the current classification of angiokeratoma. We present a case of an extensive AC in 19-year-old women with Fitzpatrick skin type I of the left lower extremity, characterized by a significant morphological heterogeneity of the lesions, intermittent bleeding, and negative psychological impact...
June 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Jiangyu Cai, Jiazhi Liu, Cunyi Fan
OBJECTIVE: To explore the effectiveness and safety of open arthrolysis combined with internal fixator removal for post-traumatic elbow stiffness. METHODS: A retrospective analysis was made on the data of 80 cases treated by open arthrolysis for elbow stiffness between January 2010 and December 2011. The patients were divided into 2 groups: no internal fixation group (group A, n = 39) and internal fixation group (group B, n = 41) according to whether they underwent internal fixator removal at the same time...
July 2015: Chinese Journal of Reparative and Reconstructive Surgery
Akira Naomi, Yasunori Oyamatsu, Kunio Narita, Masao Nakayama, Matsuyoshi Maeda
Angiosarcoma has been reported as a rare case, having high potential of hematogeneous lung metastasis and then developing to pneumothorax with ease. The patient was a 74-year-old man afflicted with a malignant hemangio endothelioma (MHE) of the scalp. His MHE of the scalp was resected and skin grafting was made, then, he was administered docetaxel hydrate intravenously as adjuvant setting. Three years after, he complainted left chest pain and dyspnea, so his chest Xp was checked up and showed left pneumothorax...
July 2015: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Helene Andrea Sinclair Ingels
Streptococcus pneumoniae is still a leading cause of septicaemia, pneumonia and meningitis in young children world-wide with over half a million children dying annually from pneumococcal disease.  Some children are prone to repeated episodes of invasive pneumococcal disease (IPD) because of an underlying predisposing disease. Recurrent IPD (rIPD) is a rarity and published reports on rIPD are limited by having few children included, selected groups of patients or short follow-up periods. Deficiencies in the innate or adaptive immune system have been described in children with rIPD, but the frequency of immunodeficiency among such patients is unknown...
July 2015: Danish Medical Journal
M Majores, E Bierhoff
Actinic (solar) keratosis is an intraepidermal squamous neoplasm of sun-damaged skin and by far the most frequent neoplastic skin lesion. A subdivison into three grades has been proposed with increasing acceptance not least because of the therapeutic consequences. The transition to invasive squamous cell carcinoma is reported in 5-10 % and with immunosuppression in 30 % of patients.Bowen's disease is a variant of squamous cell carcinoma in situ of the skin and the mucocutaneous junction. The differentiation from bowenoid papulosis as a lesion associated with human papillomavirus (HPV), actinic (solar) keratosis grade III, intraepidermal poroid lesions and in cases of clonal type from clonal seborrhoic keratosis and Paget's disease is very important...
February 2015: Der Pathologe
Christian Acksteiner, Karin Steinke
INTRODUCTION: Microwave ablation (MWA) is a relatively new minimally invasive treatment option for lung cancer with substantially lower morbidity and mortality than surgery. This retrospective study was performed to evaluate the safety, effectiveness and follow-up imaging of MWA in the elderly aged 75 years and above. METHODS: Eleven percutaneous computed tomography (CT)-guided MWA of early-stage non-small cell lung cancer (NSCLC) were performed in 10 patients aged 75 years and older...
February 2015: Journal of Medical Imaging and Radiation Oncology
Nobuki Furubayashi, Takahito Negishi, Eiji Kashiwagi, Yu Hirata, Kenichi Taguchi, Yoshihiro Hasegawa, Motonobu Nakamura
This study aimed to evaluate the usefulness of ultra-sensitive prostate-specific antigen (PSA) following radical prostatectomy (RP). Between September, 2003 and March, 2009, a total of 311 prostate cancer patients underwent antegrade RP; following the exclusion of 111 patients due to prior hormonal therapy, 200 patients were finally included in this study. The results of the multivariate analysis identified RP Gleason score, extraprostatic extension, lymph node metastasis and PSA nadir as significant predictors of biochemical failure (P=0...
September 2014: Molecular and Clinical Oncology
Christina Grothusen, Jan Schöttler, Jochen Cremer, Norbert Frey, Christoph Langer
Intra- and paracardiac tumors are rare. Clinical symptoms are typically secondary to mechanical effects of the mass. We describe a patient, who was in good general health, presenting with a 6-month history of unspecific symptoms considered consistent with reccurrent lower airway infections by her primary care physician. A chest X-ray suggested left-atrial enlargement and a questionable mass, which eventually was identified as large left-atrial tumor partially obstructing the mitral orifice. The case demonstrates that even a very large left-atrial tumor, causing intermittent partial obstruction of the mitral valve may present with mild unspecific symptoms...
February 2014: Cardiovascular Diagnosis and Therapy
Felipe Fornias Sperandio, Fernanda Salgueiredo Giudice, Décio Dos Santos Pinto-Junior, Suzana Cantanhede Orsini Machado de Sousa
BACKGROUND: Myoepitheliomas are rare tumours that may generally arise from the minor or major salivary glands. The differential diagnosis of this tumour should be performed along with several benign and malignant soft tissue neoplasms. The present case report describes an asymptomatic mass that arose in the soft palate of 42 year old black woman with duration of the six months. METHODS: An incisional biopsy of soft palate lesion was carried out and submitted for histological evaluation under the clinical hypothesis of salivary gland tumour...
2011: Journal of Oral & Maxillofacial Research
Zhiqiang Zhang, Dexin Yu, Haoqiang Shi, Dongdong Xie
Myopericytoma is a rare neoplasm that generally arises from the skin and superficial soft tissues of distal extremities, and is particularly rare in the visceral organs. The current report presents a case of giant myopericytoma showing kidney involvement, which is extremely rare. A 39-year-old male presented to the Department of Urology with a 2-month history of a painless and palpable mass in the region of the left abdomen. Unenhanced computed tomography revealed a 9×10×18-cm(3) mass that was heterogeneous with central lower density...
January 2014: Oncology Letters
N Tsoukalas, M Tolia, G Lypas, C Panopoulos, V Barbounis, G Koumakis, A Efremidis
The present study describes a rare case of a mesenteric liposarcoma that resulted in a complete remission (CR) following treatment with trabectedin (Yondelis(®)). The patient presented with abdominal pain and fever. An abdominal mass was identified that corresponded to a mixed-type high-grade mesenteric liposarcoma with wide areas of necrosis, areas of dedifferentiation and features of a leiomyosarcoma. Three months after the removal of the first mass, the patient underwent a second laparotomy, followed by treatment with doxorubicin and ifosfamide...
January 2014: Oncology Letters
Krystyna Serkies, Adam Ziemlewski, Tomasz Sawicki, Joanna Kamińska, Rafał Dziadziuszko
PURPOSE: HASH(0x2f68630) PURPOSE: To present our experience with pulsed dose rate brachytherapy (PDR BT) of lip cancer. MATERIAL AND METHODS: The study group included 32 T1-4N0M0 lip cancer patients with a median age of 71 years (ranged 41-87 years), treated with interstitial PDR BT to the planned total dose of 60-70 Gy; 1 Gy/pulse, pulses repeated every hour a day. There were 26 untreated patients, and six patients after previous surgery including five implanted at the time of cancer relapse...
September 2013: Journal of Contemporary Brachytherapy
Vittoria Martin, Elena Zanellato, Alessandra Franzetti-Pellanda, Francesca Molinari, Alessandra Movilia, Alessia Paganotti, Letizia Deantonio, Sara De Dosso, Agnese Assi, Stefano Crippa, Renzo Boldorini, Luca Mazzucchelli, Piercarlo Saletti, Milo Frattini
BACKGROUND: Combined chemoradiation therapy is the gold standard in the treatment of squamous cell anal cancer (SCAC). However, even if the response rate is very high, many patients eventually relapse or experience a reccurrence, thus requiring an invasive surgical procedure that has severe side effects. Most SCAC tumors overexpress epidermal growth factor receptor (EGFR); therefore, it is reasonable to consider anti-EGFR drugs as a new treatment option, as demonstrated by anecdotal reports...
April 2014: Histology and Histopathology
Y Samatha, T Harshavardhan Reddy, Jyothirrmai, A Ravikiran, A J Sai Sankar
Pyogenic granuloma, or granuloma pyogenicum, is a common, tumor-like growth of the oral cavity or skin that is considered to be an exaggerated, localized connective tissue reaction to a minor injury or irritation. A total of five clinical cases of oral pyogenic granuloma were randomly selected in the age group between 26 and 41 years. All these cases were treated with sodium tetra decyl sulphate and examined for regression and reccurrence of the lesion for six months. Various treatment modalities consist of conservative surgical excision, cryosurgery, laser surgery and sclerotherapy...
June 2013: New York State Dental Journal
Maria Florescu, Mircea Cinteza, Dragos Vinereanu
Breast cancer represents the most frequent form of neoplasia in women worldwide, being responsible of 1.6% of annual deaths. Therefore, it is a major public health issue and research in this field should be a priority. Chemoterapics drugs are extremly potent tools, which alone or in association to radiotherapy, increase survival and lower the reccurrence rate of cancer, but their use can be limited by cardiotoxicity. Cardiotoxicity can appear early or late after therapy, and may vary from subclinical myocardial dysfunction to irreversible heart failure...
March 2013: Mædica
V A Stupin, M V Baglaenko, V I Kan, S V Siluianov, R Iu Tronin, L A Ardabatskiĭ, R S Sokolova, A V Martirosov
The retrospective analysis (2006-2010 yy) of treatment of 895 patients with gastroduodenal ulcer bleeding was conducted. Lethal outcome was registered in 220 (24.6%) patients, of them directly of the ulcer bleeding died 45 (5%). The Rockall score was used as universal prognostic instrument. Of 164 lethal outcomes, did not directly connected to the ulcer bleeding, the etiological distribution was as follows: multiple organ failure - 36% (n=59), cardiovascular diseases - 24.4% (n=40), inveterate oncology - 15...
2013: Khirurgiia
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