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https://www.readbyqxmd.com/read/29135152/-masks-of-urogenital-tuberculosis-as-the-cause-of-diagnostic-errors
#1
D P Kholtobin, E K Kulchavenya
Urogenital tuberculosis does not have pathognomonic symptoms, so diagnostic errors are quite common. This systematic review of literature was conducted to identify the causes and estimate the incidence of erroneous diagnoses. We critically evaluated some articles in which the authors describe observations of urogenital tuberculosis as rare and unusual because they never encountered this disease, but in fact that were typical manifestations of genitourinary tuberculosis. The authors analyzed and illustrated the features of urinary tuberculosis in patients with pulmonary tuberculosis, differential diagnosis of urogenital tuberculosis and kidney cancer and male genitourinary organs, described errors in the diagnosis of urethral, testicular, penile, prostatic and epididymal tuberculosis...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29126844/prospective-outcome-analysis-of-the-safety-and-efficacy-of-partial-and-complete-cryoablation-in-organ-confined-prostate-cancer
#2
A Barqawi, E Huebner, K Krughoff, C I O'Donnell
OBJECTIVES: To determine the rate of complications and change in IPSS and SHIM scores following cryotherapy treatment of low and intermediate risk prostate cancer. Secondary endpoint was change in PSA post-cryotherapy and biopsy-proven recurrence. METHODS: Enrollment occurred from 2007-2015 to assess long-term complications of cryotherapy. A prostate biopsy was performed at one year or in the event of biochemical failure. Subjects were staged and graded by standard 12-14 core TRUS biopsy...
November 7, 2017: Urology
https://www.readbyqxmd.com/read/29113768/female-urethra-adenocarcinoma
#3
REVIEW
Lucio Dell'Atti, Andrea Benedetto Galosi
Female urethra adenocarcinoma (FUA) is a rare aggressive tumor that occurs in Skene ducts and glands. It is associated with a relatively poor prognosis. The aim of this review was to evaluate FUA in terms of epidemiology, risk factors, diagnosis, natural history of disease, modalities of treatment, and outcomes. These tumors are usually large masses, which typically spread through the lymphatic system. Patients present with vague symptoms similar to urinary tract infections. Cystourethroscopy permits visualization of the urethral tumor and allows biopsies to be performed to remove samples for histologic examination...
October 16, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29102738/manual-vs-automated-implantation-of-seeds-in-prostate-brachytherapy-oncologic-results-from-a-single-center-study
#4
Laurence Thomas, Antony Chemin, Nicolas Leduc, Sarah Belhomme, Emilie Rich, Olivier Lasbareilles, Antoine Giraud, Edouard Descat, Guilhem Roubaud, Paul Sargos
PURPOSE: The objective of this study was to study survival and tolerance of prostate cancer patients treated with (125)I permanent interstitial brachytherapy by automated vs. manual implantation of seeds. METHODS AND MATERIALS: Between 2002 and 2010, 349 selected patients were treated with (125)I brachytherapy by the same team: from 2002 to April 2005, 65 patients with linked seeds and then 284 patients treated using Nucletron First System automated implantation...
November 1, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29102424/lower-tract-neoplasm-update-of-imaging-evaluation
#5
REVIEW
Robert Hartman, Akira Kawashima
Cancers of the lower urinary tract can arise from the bladder, urachus or urethra. Urothelial carcinoma of the bladder (UCB) is the most common of these. The presentation of bladder, urachal and urethral cancers can differ but many result in hematuria as an initial indication. The diagnosis and staging of these cancers often necessitate radiologic imaging often in the form of cross-section CT urography or MR urography. The following article reviews the specific nature of lower tract cancers and their imaging...
November 1, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29089276/long-term-evaluation-of-urinary-sexual-and-quality-of-life-outcomes-after-brachytherapy-for-penile-carcinoma
#6
Dimitri Gambachidze, Cédric Lebacle, Pierre Maroun, Alexandre Escande, Alberto Bossi, Pierre Blanchard, Eric Deutsch, Christine Haie-Meder, Cyrus Chargari
PURPOSE: Brachytherapy (BT) is an effective organ-preserving treatment for selected localized penile carcinoma, providing high local control rates. Long-term functional results however, are still insufficiently evaluated. METHODS AND MATERIALS: All consecutive patients treated with low-dose-rate or pulse-dose-rate BT in our institute for a localized penile cancer and who were in first complete remission and followed for at least 3 years were included. A self-reporting questionnaire was sent, to assess: 1/urinary function, 2/sexual function, 3/cosmetic aspect of the penis, and 4/quality of life...
October 28, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29071155/risk-factors-and-prognosis-of-intravesical-recurrence-after-surgical-management-of-upper-tract-urothelial-carcinoma-a-30-year-single-centre-experience
#7
Mohamed Mohamed Elawdy, Yasser Osman, Diaa Eldin Taha, Mohamed H Zahran, Samer El-Halwagy, Muftah El Garba, Ahmed M Harraz
OBJECTIVE: To review the incidence, predictors and prognosis of bladder cancer recurrence after management of upper tract urothelial carcinoma (UTUC). PATIENTS AND METHODS: We retrospectively reviewed patients who were surgically treated for UTUC from 1983 to 2013. The tumours were categorised according to the 1997 Tumour-Node-Metastasis (TNM) staging and the three-tiered World Health Organization grading systems. The primary endpoint was the occurrence of any intravesical recurrence after treatment...
September 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29061068/three-layer-two-step-posterior-reconstruction-using-peritoneum-during-robot-assisted-radical-prostatectomy-to-improve-recovery-of-urinary-continence-prospective-comparative-study
#8
Souichiro Ogawa, Seiji Hoshi, Tomoyuki Koguchi, Junya Hata, Yuichi Sato, Hidenori Akaihata, Masao Kataoka, Nobuhiro Haga, Yoshiyuki Kojima
INTRODUCTION: We present our experience with a novel 3-layer 2-step posterior reconstruction (PR) technique using peritoneum during robot-assisted radical prostatectomy (RARP) to improve recovery of postoperative urinary continence. METHODS: Forty-eight patients with localized prostate cancer were enrolled in this study and were divided randomly into 2 groups, which were treated by the standard PR technique (standard PR group; n=24) or the 3-layer PR technique using peritoneum (3-layer PR group; n=24) during RARP...
October 23, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29055518/the-prognostic-effect-of-salvage-surgery-and-radiotherapy-in-patients-with-recurrent-primary-urethral-carcinoma
#9
Georgios Gakis, Tina Schubert, Todd M Morgan, Siamak Daneshmand, Kirk A Keegan, Johannes Mischinger, Rebecca H Clayman, Antonin Brisuda, Bedeir Ali-El-Dein, Sigolene Galland, Justin Gregg, Melih Balci, Kola Olugbade, Michael Rink, Hans-Martin Fritsche, Maximilian Burger, Marko Babjuk, Arnulf Stenzl, George N Thalmann, Hubert Kübler, Jason A Efstathiou
BACKGROUND: To evaluate the impact of salvage therapy (ST) on overall survival (OS) in recurrent primary urethral cancer (PUC). PATIENTS: A series of 139 patients (96 men, 43 women; median age = 66, interquartile range: 57-77) were diagnosed with PUC at 10 referral centers between 1993 and 2012. The modality of ST of recurrence (salvage surgery vs. radiotherapy) was recorded. Kaplan-Meier analysis with log-rank was used to estimate the impact of ST on OS (median follow-up = 21, interquartile range: 5-48)...
October 18, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28984165/target-definition-in-salvage-postoperative-radiotherapy-for-prostate-cancer-18f-fluorocholine-pet-ct-assessment-of-local-recurrence
#10
Osman El Kabbaj, Philippe Robin, David Bourhis, Gurvan Dissaux, Nicola Rosenfelder, Antoine Valeri, Georges Fournier, Pierre-Yves Salaun, Olivier Pradier, Jean-Pierre Malhaire, Ronan Abgral, Ulrike Schick
PURPOSE: Inadequate clinical target volume (CTV) definition is likely to be a major contributing factor to local recurrence (LR) rate after radiotherapy. Our aims were to identify sites of prostate cancer LR in biochemical recurrence post-prostatectomy using (18)F-Fluorocholine (18F-FCH) positron emission tomography/computed tomography (PET/CT) and to compare different CTV-delineation guidelines in a cohort of postoperative patients. MATERIAL AND METHODS: Thirty-six patients presenting with LR within the prostatic bed on 18F-FCH PET/CT between 10/2011 and 06/2016 were included in this retrospective study...
October 6, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28979650/-urethral-ectropion-may-hide-a-carcinoma
#11
Mohammed Alae Touzani, Othmane Yddoussalah
The incidence of female urethral cancer is rare and accounts for 0.02% of all women's cancers. It is dominated by epidermoid carcinoma, which most commonly develops in the distal portion of the urethra, extending to inguinal lymph nodes. The diagnosis is confirmed in the distal forms on the basis of uretrocystoscopy with biopsy. Abdominopelvic MRI allows to determine tumor extension as well as its infiltration into tissues and peri-urethral organs. As in superficial tumors of the distal urethra, simple circumferential resection of the urethra associated with resection of the adjacent portion of the anterior surface of the vagina is sufficient...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28977739/denonvilliers-fascia-in-men-a-sheet-plastination-and-confocal-microscopy-study-of-the-prerectal-space-and-the-presence-of-an-optimal-anterior-plane-when-mobilizing-the-rectum-for-cancer
#12
Zhaoyang Xu, Pierre H Chapuis, Les Bokey, Ming Zhang
AIM: The aim of this study was to investigate the detailed, in situ, morphology of Denonvilliers fascia (DVF) in cadavers using sheet plastination and confocal microscopy and to review and describe the optimal anterior plane for mobilisation of the distal rectum.. METHOD: Six, male cadavers (age range, 46-87 years) were prepared as six sets of transverse (x2), coronal (x1) and sagittal (x3) plastinated sections which were examined under a confocal laser scanning microscope...
October 4, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28939178/prostate-cancer-post-prostatectomy-radiotherapy-ct-vs-mri-for-vesico-urethral-anastomosis-target-delineation
#13
Daryl Lim Joon, Adeline Lim, Michal Schneider, Chee-Yan Hiew, Nathan Lawrentschuk, Shomik Sengupta, Farshad Foroudi, Trish Jenkins, David Angus, Morikatsu Wada, Michael Chao, Vincent Khoo
BACKGROUND: Vesico-urethral anastomosis (VUA) is critical to the clinical target volume (CTV) in post-prostatectomy radiotherapy (PPRT), as it is the commonest site of recurrence. Typically, this is performed on a CT alone but guidelines recommend MRI. OBJECTIVE: To evaluate the VUA spatial differences between CT (ctVUA) and MRI (mrVUA) and analyse its impact on the CT defined CTV (ctCTV) as recommended by published guidelines. MATERIALS AND METHODS: We identified 34 patients with a co-registered simulation CT and T2 weighted MRI...
October 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28923700/venous-thromboembolism-risk-in-patients-with-locoregional-urothelial-tract-tumors
#14
Jorge D Ramos, Jonathan T Wingate, Roman Gulati, Elizabeth R Plimack, Lauren C Harshman, Thomas Powles, Simon J Crabb, Guenter Niegisch, Joaquim Bellmunt, Sylvain Ladoire, Ugo De Giorgi, Syed Hussain, Ajjai S Alva, Jack Baniel, Neeraj Agarwal, Jonathan E Rosenberg, Ulka N Vaishampayan, Matthew D Galsky, Evan Y Yu
BACKGROUND: Venous thromboembolism (VTE) is common in cancer patients, but there is limited data on patients with urothelial tract tumors (UTT). We previously identified several associative factors for increased VTE rates in patients with metastatic UTT. In this study, we assessed the frequency, associative factors, and impact on survival of VTE in patients with locoregional UTT. METHODS: Patients with locoregional bladder, upper urinary tract, or urethral cancer were included in this multi-center study from 29 academic institutions...
August 24, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28916253/the-place-of-transanal-endoscopic-surgery-in-the-treatment-of-rectourethral-fistula
#15
Xavier Serra-Aracil, Meritxell Labró-Ciurans, Laura Mora-López, Jesús Muñoz-Rodríguez, Raúl Martos-Calvo, Joan Prats-López, Salvador Navarro-Soto
OBJECTIVE: To assess the role of transanal endoscopic operation (TEO) or transanal endoscopic microsurgery (TEM) in rectourethral fistulas (RUF). RUF may appear after radical prostatectomy. Their treatment represents a challenge; many therapies have been proposed, from conservative to aggressive surgical approaches. Transanal endoscopic surgery (TEO or TEM) is a minimally invasive technique to access the site of the RUF to perform repair. MATERIALS AND METHODS: This is an observational study with prospective data collection, conducted between September 2006 and December 2015...
September 12, 2017: Urology
https://www.readbyqxmd.com/read/28891845/uptake-of-transanal-total-mesorectal-excision-in-north-america-initial-assessment-of-a-structured-training-program-and-the-experience-of-delegate-surgeons
#16
Sam B Atallah, Arielle C DuBose, John P Burke, George Nassif, Teresa deBeche-Adams, Taylor Frering, Matthew R Albert, John R T Monson
BACKGROUND: Transanal total mesorectal excision is a new approach to curative-intent rectal cancer surgery. Training and surgeon experience with this approach has not been assessed previously in America. OBJECTIVE: The purpose of this study was to characterize a structured training program and to determine the experience of delegate surgeons. DESIGN: Data were assimilated from an anonymous, online survey delivered to attendees on course completion...
October 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28889719/-two-cases-of-urethral-clear-cell-adenocarcinoma-with-suspected-recurrence-of-uterine-cancer
#17
Masato Okuno, Yuji Kusuda, Isao Taguchi, Gaku Kawabata
Herein, we report two cases of urethral clear cell carcinoma in two patients who had previously undergone radical hysterectomyfor utetine cancer. Case 1 presented with bloodyvaginal discharge and case 2 presented with acute urinaryretention. Magnetic resonance imaging revealed a periurethral tumor in both cases. Both cases were suspected to be recurrence at first. However, pathological findings of the transurethral resection-biopsyshowed clear cell adenocarcinoma in both cases. Subsequentlyradical cystourethrectomy and pelvic lymphadenectomy were performed in both cases...
August 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28882961/efficacy-of-n-acetylcysteine-d-mannose-and-morinda-citrifolia-to-treat-recurrent-cystitis-in-breast-cancer-survivals
#18
Debora Marchiori, Pier Paolo Zanello
BACKGROUND/AIM: Breast cancer survivors in adjuvant therapy, frequently experience the estrogen deficiency with genitourinary symptoms mostly represented by recurrent bacterial cystitis. The objective of the present study was to evaluate the effectiveness of N-acetylcysteine, D-mannose and Morinda citrifolia fruit extract (NDM), when associated to antibiotic therapy, in reducing the persistence of recurrent cystitis in this risk population. PATIENTS AND METHODS: Sixty breast cancer survived women with recurrent cystitis were retrospectively examined...
September 2017: In Vivo
https://www.readbyqxmd.com/read/28882777/secondary-urethral-malignancies-following-prostate-brachytherapy
#19
Shree Agrawal, John M Lacy, Herman Bagga, Kenneth W Angermeier, Jay Ciezki, Rahul D Tendulkar, Chandana A Reddy, Hadley M Wood
OBJECTIVE: To understand urethral secondary malignancies among patients treated with brachytherapy (BRT) for primary prostate cancer. METHODS: Institutional retrospective review identified 13 patients evaluated from 2003-2014 with urethral cancer and prior history of BRT monotherapy for prostate cancer. All patients were biochemically free of their primary disease and developed histologically distinct RASM from primary tumor via pathologic confirmation. BRT characteristics, patient age, presentation, staging work-up and clinical course were evaluated...
September 4, 2017: Urology
https://www.readbyqxmd.com/read/28861306/the-predictive-value-of-platelet-to-lymphocyte-and-neutrophil-to-lymphocyte-ratio-in-determining-urethral-stricture-after-transurethral-resection-of-prostate
#20
Murat Gül, Emre Altıntaş, Mehmet Kaynar, Muhammet Serdar Buğday, Serdar Göktaş
OBJECTIVE: The pathology of urethral stricture disease is still unclear however progressive inflammation may contribute to the development of urethral stricture. The platelet-to- lymphocyte ratio (PLR) is a new and simple marker that indicates inflammation. In this study we aimed to investigate the predictive value of neutrophil to lymphocyte ratio (NLR) and PLR in patients with urethral stricture who underwent transurethral resection of prostate (TURP). MATERIAL AND METHODS: A total of 208 patients who underwent bipolar-TURP were included in this study...
September 2017: Turkish Journal of Urology
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