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https://www.readbyqxmd.com/read/28718165/surgical-techniques-to-optimize-early-urinary-continence-recovery-post-robot-assisted-radical-prostatectomy-for-prostate-cancer
#1
REVIEW
Ashwin N Sridhar, Mohammed Abozaid, Prabhakar Rajan, Prasanna Sooriakumaran, Greg Shaw, Senthil Nathan, John D Kelly, Tim P Briggs
PURPOSE OF REVIEW: A variety of different surgical techniques are thought to impact on urinary continence (UC) recovery in patients undergoing robot assisted radical prostatectomy (RARP) for prostate cancer. Herein, we review current evidence and propose a composite evidence-based technique to optimize UC recovery after RARP. RECENT FINDINGS: A literature search on studies reporting on surgical techniques to improve early continence recovery post robotic prostatectomy was conducted on PubMed and EMBASE...
September 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28716790/human-papillomavirus-prevalence-and-genotype-distribution-among-young-women-and-men-in-maputo-city-mozambique
#2
Viegas Edna Omar, Augusto Orvalho, Ismael Nália, Kaliff Malin, Lillsunde-Larsson Gabriella, Ramqvist Torbjörn, Nilsson Charlotta, Falk Kerstin, Osman Nafissa, Jani Ilesh Vindorai, Andersson Sören
OBJECTIVES: Human papillomavirus (HPV) is a well-known cause of cervical cancer, the second most frequent cancer in female African populations. This study aimed at determining the prevalence of HPV infections and the genotype distribution in young adults aged 18-24, in Maputo city, Mozambique, and to assess the suitability of commercially available HPV vaccines. METHODS: This cross-sectional study was conducted between 2009 and 2011 at a youth clinic in Maputo Central Hospital...
July 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28703328/insight-into-infection-mediated-prostate-damage-contrasting-patterns-of-c-reactive-protein-and-prostate-specific-antigen-levels-during-infection
#3
Melissa Milbrandt, Anke C Winter, Remington L Nevin, Ratna Pakpahan, Gary Bradwin, Angelo M De Marzo, Debra J Elliott, Charlotte A Gaydos, William B Isaacs, William G Nelson, Nader Rifai, Lori J Sokoll, Jonathan M Zenilman, Elizabeth A Platz, Siobhan Sutcliffe
BACKGROUND: To investigate mechanisms underlying our previous observation of a large rise in serum prostate-specific antigen, a marker of prostate pathology, during both sexually transmitted and systemic infections, we measured serum high-sensitivity C-reactive protein (hsCRP), a marker of systemic inflammation, in our previous case-control study of young, male US military members and compared our findings to those for PSA. METHODS: We measured hsCRP before and during infection for 299 chlamydia, 112 gonorrhea, and 59 non-chlamydial, non-gonococcal urethritis (NCNGU) cases; before and after infection for 55 infectious mononucleosis (IM) and 90 other systemic/non-genitourinary cases; and for 220-256 controls...
July 12, 2017: Prostate
https://www.readbyqxmd.com/read/28681033/the-impact-of-incontinence-etiology-on-artificial-urinary-sphincter-outcomes
#4
Adam R Miller, Brian J Linder, Laureano J Rangel, David Y Yang, Daniel S Elliott
PURPOSE: To evaluate the impact of incontinence etiology on artificial urinary sphincter (AUS) device outcomes. MATERIALS AND METHODS: We identified 925 patients who underwent primary AUS placement from 1983 to 2011. The etiology of incontinence was categorized as radical prostatectomy alone, radical prostatectomy with radiation, benign prostate resection, and those with cryotherapy as a salvage prostate cancer treatment. Hazard regression and competing risk analyses were used to determine the association of the etiology of incontinence with device outcomes...
July 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28652453/predictive-factors-for-prolonged-urination-disorder-after-permanent-125-i-brachytherapy-for-localized-prostate-cancer
#5
Hidehisa Mori, Tomoharu Fukumori, Kei Daizumoto, Megumi Tsuda, Yoshihito Kusuhara, Tomoya Fukawa, Yasuyo Yamamoto, Kunihisa Yamaguchi, Masayuki Takahashi, Akiko Kubo, Takashi Kawanaka, Shunsuke Furutani, Hitoshi Ikushima, Hiro-Omi Kanayama
BACKGROUND: We assessed the change in LUTS after prostate brachytherapy to reveal factors for prolonged urination disorder. MATERIALS AND METHODS: Four hundred and four patients received prostate brachytherapy at our institution and were followed-up for at least 2 years. We evaluated the correlation of mean IPSS changes and clinical factors. Using multivariate analysis, we also evaluated clinical factors with potential to delay IPSS resolution. RESULTS: In cases with prostate volume more than 30 cm(3), radiation dose to 90% of prostate volume (D90) more than 160 Gy, and radiation dose to 30% of the urethral volume (UD30) more than 240 Gy, mean IPSS levels were significantly higher, even 30 months after treatment...
July 2017: In Vivo
https://www.readbyqxmd.com/read/28647400/intraoperative-registered-ultrasound-and-fluoroscopy-iruf-for-dose-calculation-during-prostate-brachytherapy-improved-accuracy-compared-to-standard-ultrasound-based-dosimetry
#6
Junghoon Lee, Omar Y Mian, Yi Le, Hee Joon Bae, E Clif Burdette, Theodore L DeWeese, Jerry L Prince, Daniel Y Song
BACKGROUND AND PURPOSE: Intraoperative transrectal ultrasound dosimetry during low-dose-rate prostate brachytherapy is imprecise due to sonographic distortion caused by seed echoes and needle tracks that obscure seed positions or create false signals as well as traumatic edema. Here we report the results of a pilot study comparing a combined ultrasound and fluoroscopy-based seed localization method (iRUF) to standard ultrasound-based dosimetry (USD). MATERIAL AND METHODS: Eighty patients undergoing permanent Pd-103 seed implantation for prostate cancer were prospectively enrolled...
June 21, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28601562/patterns-of-benign-prostate-hyperplasia-based-on-magnetic-resonance-imaging-are-correlated-with-lower-urinary-tract-symptoms-and-continence-in-men-undergoing-a-robot-assisted-radical-prostatectomy-for-prostate-cancer
#7
Nikolaos Grivas, Rosanne van der Roest, Corinne Tillier, Daan Schouten, Erik van Muilekom, Ivo Schoots, Henk van der Poel, Stijn Heijmink
OBJECTIVE: To investigate the association between benign prostatic hyperplasia (BPH) patterns, classified by magnetic resonance imaging (MRI), with lower urinary tract symptoms (LUTS) or continence, preoperatively and after robot-assisted laparoscopic radical prostatectomy (RARP). MATERIALS AND METHODS: This retrospective study included 49 prostate cancer patients, with prostate size >47 cm(3), who underwent an endorectal MRI followed by RARP. Five BPH patterns were identified according to Wasserman and additional prostate measurements were recorded...
June 7, 2017: Urology
https://www.readbyqxmd.com/read/28587272/association-of-smoking-alcohol-use-and-betel-quid-chewing-with-epigenetic-aberrations-in-cancers
#8
REVIEW
Tong-Hong Wang, Shih-Min Hsia, Yin-Hwa Shih, Tzong-Ming Shieh
Numerous environmental factors such as diet, alcohol use, stress, and environmental chemicals are known to elicit epigenetic changes, leading to increased rates of cancers and other diseases. The incidence of head and neck cancer, one of the most common cancers in Taiwanese males, is increasing: oral cancer and nasopharyngeal carcinoma are ranked fourth and tenth respectively, among the top ten cancers in this group, and a major cause of cancer-related deaths in Taiwanese males. Previous studies have identified smoking, alcohol use, and betel quid chewing as the three major causes of head and neck cancers; these three social habits are commonly observed in Taiwanese males, resulting in an increasing morbidity rate of head and neck cancers in this population...
June 6, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28586158/quantitative-assessment-of-fascia-preservation-improves-the-prediction-of-membranous-urethral-length-and-inner-levator-distance-on-continence-outcome-after-robot-assisted-radical-prostatectomy
#9
Nikolaos Grivas, Rosanne van der Roest, Daan Schouten, Francesca Cavicchioli, Corine Tillier, Axel Bex, Ivo Schoots, Walter Artibani, Stijn Heijmink, Henk Van Der Poel
AIMS: To determine whether preoperative prostate/pelvic anatomical structures and intraoperative fascia preservation (FP) predict continence recovery after robot-assisted radical prostatectomy (RARP). METHODS: Between January 2012 and March 2016, 439 prostate cancer (PCa) patients with normal preoperative continence were retrospectively included. FP score was defined as the extent of FP from base to apex of the prostate, quantitatively assessed by the surgeon. Anatomical prostate structures were measured on endorectal preoperative Magnetic Resonance Imaging...
June 6, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28579068/the-impact-of-age-on-urethroplasty-success
#10
Mya Levy, Ronak A Gor, Alex J Vanni, Kristian Stensland, Bradley A Erickson, Jeremy B Myers, Bryan B Voelzke, Thomas G Smith, Benjamin N Breyer, Christopher McClung, Nejd F Alsikafi, Yunhua Fan, Sean P Elliott
OBJECTIVE: To determine if age is an independent predictor of surgical success in patients undergoing urethroplasty. Urethroplasty performed by excision and primary anastomosis depends on vascular collateralization. Successful augmented urethroplasty depends on graft neovascularization. Older patients have more comorbid conditions including peripheral vascular disease associated with reduced penile blood flow. MATERIALS AND METHODS: A retrospective review of urethroplasties from 11 institutions...
June 1, 2017: Urology
https://www.readbyqxmd.com/read/28537991/treatment-and-outcomes-of-primary-urethra-cancer
#11
Tony Y Eng, Tiffany W Chen, Abhilasha J Patel, Jill N Vincent, Chul S Ha
BACKGROUND: Urethral cancer is a rare malignancy, representing <1% of all malignancies. Optimal management, due to its rarity, presents as a treatment dilemma for physicians. There is a lack of consensus regarding treatment as large randomized trials cannot be performed; thus, optimal management decisions rely on study of retrospective cases. This is a review of our institutional experience with urethral cancer treated with various treatment modalities. METHODS: A retrospective chart review was performed on 31 patients treated for primary cancer of the urethra from 1958 to 2008...
May 23, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28534091/transanal-total-mesorectal-excision-with-intersphincteric-resection-and-use-of-fluorescent-angiography-and-a-lighted-urethral-stent-for-distal-rectal-cancer
#12
A Mabardy, L Lee, A P Valpato, S Atallah
No abstract text is available yet for this article.
May 22, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28479762/transurethral-resection-of-prostate-in-benign-prostatic-enlargement-with-underactive-bladder-a-retrospective-outcome-analysis
#13
Ashok Kumar Sokhal, Rahul Janak Sinha, Bimalesh Purkait, Vishwajeet Singh
PURPOSE: The purpose of this study was to evaluate the clinical outcome and efficacy of transurethral resection of the prostate in patients of benign prostatic enlargement (BPE) with underactive bladder. MATERIALS AND METHODS: Retrospective study of 174 patients, who underwent transurethral resection of prostate (TURP) between 2008 and 2015, for lower urinary tract symptoms with BPE with bladder underactivity. Clinical history, physical examination, renal function test, urinalysis, cystourethroscopy, transabdominal or transrectal ultrasonography, and urodynamic study were recorded...
April 2017: Urology Annals
https://www.readbyqxmd.com/read/28476381/unusual-asymptomatic-presentation-of-bladder-cancer-metastatic-to-the-penis
#14
Francesca Giunchi, Francesco Vasuri, Vagnoni Valerio, Ilaria Montagnani, Federico Nelli, Michelangelo Fiorentino, Maria Rosaria Raspollini
Penile metastasis is an extremely rare event and mainly originate from primary pelvic tumor sites such us urinary bladder, gastro-intestinal tract and prostate and more rarely from respiratory system, bone tumors and melanoma. Here we describe the unusual presentation of two bladder urothelial cancer metastatic to the penis with no relevant clinical symptoms. Namely, a 69 years-old man with a warthy lesions of the foreskin and the glans misunderstood for a condylomata that at histological and immunohistochemical analysis showed a bladder urothelial carcinoma; and a 71 years-old man with reddish skin lesion of the glans, a previous history of bladder and urethral carcinoma and histological pagetoid spread of urothelial cancer to the glans...
June 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28460994/erectile-dysfunction-treatment-following-radical-cystoprostatectomy-analysis-of-a-nationwide-insurance-claims-database
#15
Meera R Chappidi, Max Kates, Nikolai A Sopko, Gregory A Joice, Jeffrey J Tosoian, Phillip M Pierorazio, Trinity J Bivalacqua
INTRODUCTION: To improve care for patients after radical cystoprostatectomy (RCP), focus on survivorship issues such as sexual function needs to increase. Previous studies have demonstrated the burden of erectile dysfunction (ED) after RCP to be as high as 89%. AIM: To determine the rates of ED treatment use (phosphodiesterase type 5 inhibitors, injectable therapies, urethral suppositories, vacuum erection devices, and penile prosthetics) in patients with bladder cancer before and after RCP to better understand current patterns of care...
June 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28434947/effect-of-urinary-cytology-for-detecting-recurrence-in-remnant-urothelium-after-radical%C3%A2-cystectomy-insights-from-a-10-year-cytology-database
#16
Renate Pichler, Gennadi Tulchiner, Wilhelm Oberaigner, Georg Schaefer, Wolfgang Horninger, Andrea Brunner, Isabel Heidegger
BACKGROUND: We evaluated the diagnostic accuracy of urinary cytology (UCy) for detecting recurrence in the remnant urothelium (RRU) after radical cystectomy (RC) for urothelial cancer. PATIENTS AND METHODS: We conducted a 10-year retrospective analysis of a prospectively collected, single-center RC database comprising 177 patients who had undergone follow-up examinations at our department with ≥ 1 available postoperative UCy specimen. UCy specimens were classified using the Papanicolaou scheme...
March 30, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28433640/partial-gland-treatment-of-prostate-cancer-utilizing-high-intensity-focused-ultrasound-in-the-primary-and-salvage-setting-a-systematic-review
#17
REVIEW
Ron Golan, Adrien N Bernstein, Timothy D McClure, Art Sedrakyan, Neal A Patel, Dipen J Parekh, Leonard S Marks, Jim C Hu
PURPOSE: Advances in prostate imaging, biopsy and ablative technologies have been accompanied by growing enthusiasm for partial gland ablation, particularly using high-intensity focused ultrasound (HIFU) for treating prostate cancer. The preservation of non-cancerous prostate tissue and minimizing damage to the neurovascular bundles and external urethral sphincter may improve functional outcomes. MATERIALS AND METHODS: A systematic review was performed following the PRISMA guidelines using a combination of MeSH terms, free-text search, and review of relevant bibliographies using Medline and Embase from the inception of each database through October 10, 2016...
April 19, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28417077/direct-extension-of-prostatic-adenocarcinoma-protruding-through-the-urethral-meatus
#18
Hasan Jhaveri, Kristen Combs, Faiyaaz Jhaveri
Prostate cancer involving the anterior urethra is rare with few cases describing isolated recurrence to the anterior urethra. This case describes a patient with a history of metastatic prostate cancer who subsequently developed advanced prostate cancer involving the entire urethra with extension from the prostatic urethra to the urethral meatus. This will help future healthcare providers recognize this metastatic pattern as a possibility and explore this option when presented with a bleeding mass at the urethral meatus of unknown origin...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28408986/pain-management-using-acetaminophen-throughout-postoperative-course-of-laparoscopic-colorectal-surgery-a-case-matched-control-study
#19
Masanori Naito, Takeo Sato, Takatoshi Nakamura, Takahiro Yamanashi, Hirohisa Miura, Atsuko Tsutsui, Masahiko Watanabe
BACKGROUD: The main advantage of laparoscopic surgery is that it is minimally invasive because of the use of small incisions. An approach using small incisions offers many benefits including attenuation of surgical wound pain. However, the presence of postoperative pain may undermine the advantages of laparoscopic surgery as a minimally invasive technique. In addition, perioperative pain management is an important factor affecting recovery after surgery. This study investigated the usefulness of a multimodal approach to postoperative pain management with acetaminophen as a baseline analgesic after minimally invasive laparoscopic colorectal surgery...
May 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28398951/challenges-in-pathologic-staging-of-bladder-cancer-proposals-for-fresh-approaches-of-assessing-pathologic-stage-in-light-of-recent-studies-and-observations-pertaining-to-bladder-histoanatomic-variances
#20
REVIEW
Gladell P Paner, Rodolfo Montironi, Mahul B Amin
The paradigm of pathologic stage (pT) categorization in bladder cancer remains the depth of invasion into the different histologic layers of the bladder wall. However, the approaches to assigning pT stage category toward an enhanced outcome stratification have been marked by challenges and innovations, due in part to our growing appreciation of the surprisingly perplexing bladder histoanatomy. Upstaging of pT1 tumors after radical cystectomy is substantial and underscores the potential value of pT1 substaging in transurethral resection (TUR) specimens...
May 2017: Advances in Anatomic Pathology
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