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Urethral cancer

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https://www.readbyqxmd.com/read/29339302/bilateral-ureteral-stent-remove-after-15-years-a-case-report
#1
Stefano Restaino, Francesco Fanfani, Matteo Vittori, Alessandro D'Addessi, Giovanni Scambia, Barbara Costantini
We present the first case of patients with more than 15 years forgotten ureteral stents. A 68-year-old woman affected by cervical cancer, who underwent a radical hysterectomy in 1997 and reported a placement of bilateral ureteral stents. She was admitted in our Hospital for stranguria, dysuria, and lower back pain for 10 days. Preoperative radiological evaluation showed the persistence of ureteral stents. She never removed the stent which had been positioned for a long period of time(since 1997). We proceed to remove in general anaesthesia bilateral stents by urethral cystoscopic...
January 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29333958/focal-mri-guided-salvage-high-dose-rate-brachytherapy-in-patients-with-radiorecurrent-prostate-cancer
#2
Metha Maenhout, Max Peters, Marco van Vulpen, Marinus A Moerland, Richard P Meijer, Maurice A A J van den Bosch, Paul L Nguyen, Steven J Frank, Jochem R N van der Voort van Zyp
INTRODUCTION: Whole-gland salvage treatment of radiorecurrent prostate cancer has a high rate of severe toxicity. The standard of care in case of a biochemical recurrence is androgen deprivation treatment, which is associated with morbidity and negative effects on quality of life. A salvage treatment with acceptable toxicity might postpone the start of androgen deprivation treatment, might have a positive influence on the patients' quality of life, and might even be curative. Here, toxicity and biochemical outcome are described after magnetic resonance imaging-guided focal salvage high-dose-rate brachytherapy in patients with radiorecurrent prostate cancer...
December 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/29333514/what-is-the-fate-of-artificial-urinary-sphincters-among-men-undergoing-repetitive-bladder-cancer-treatment
#3
S Mitchell Heiner, Boyd R Viers, Marcelino E Rivera, Brian J Linder, Daniel S Elliott
Purpose: Functional characteristics and durability of the artificial urinary sphincter (AUS) among patients who develop bladder cancer has been poorly characterized. We sought to evaluate AUS outcomes among patients subsequently diagnosed with bladder cancer, in order to describe device survivability when subject to diagnostic and therapeutic procedures such as cystoscopy, transurethral resection, and cystectomy. Materials and Methods: We retrospectively reviewed 1,803 male patients treated with AUS surgery at a single institution between 1983-2014...
January 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29305945/urosymphyseal-fistulas-resulting-from-endoscopic-treatment-of-radiation-induced-posterior-urethral-strictures
#4
Daniel D Shapiro, David C Goodspeed, Wade Bushman
Objective To describe the inciting events leading to urosymphyseal fistulas (UF) and pubic osteomyelitis (PO) in patients who had radiation induced urethral strictures. Materials and Methods We retrospectively reviewed patients who underwent simultaneous pubic debridement, simple cystectomy and urinary diversion for refractory UF and PO from 2014-2016. We investigated inciting events leading to UF as well as patient presenting symptoms, diagnosis, management, and outcomes. Results Five patients were identified over a two-year period...
January 3, 2018: Urology
https://www.readbyqxmd.com/read/29304797/suprapubic-tube-versus-urethral-catheter-drainage-after-robot-assisted-radical-prostatectomy-a-systematic-review-and-meta-analysis
#5
Zhongyu Jian, Shijian Feng, Yuntian Chen, Xin Wei, Deyi Luo, Hong Li, Kunjie Wang
BACKGROUND: Prostate cancer is one of the most common cancers in the elderly population. The standard treatment is radical prostatectomy (RARP). However, urologists do not have consents on the postoperative urine drainage management (suprapubic tube (ST)/ urethral catheter (UC)). Thus, we try to compare ST drainage to UC drainage after robot-assisted radical prostatectomy regarding to comfort, recovery rate and continence using the method of meta-analysis. METHODS: A systematic search was performed in Dec...
January 5, 2018: BMC Urology
https://www.readbyqxmd.com/read/29300208/review-of-optimal-techniques-for-robotic-assisted-radical-prostatectomy
#6
Khushabu Kasabwala, Neal A Patel, Jim C Hu
PURPOSE OF REVIEW: Robotic-assisted radical prostatectomy has been rapidly adopted and is now the standard of care in the surgical management of prostate cancer. Since the initial description in 2001, the technique has evolved to optimize oncological functional outcomes. Herein, we review key techniques for the robotic-assisted radical prostatectomy. RECENT FINDINGS: With the current influx of new technology such as focal therapy, stereotactic body radiation therapy and prostate-sparing treatments, there is greater emphasis on maximizing outcomes of robotic-assisted radical prostatectomy...
January 2, 2018: Current Opinion in Urology
https://www.readbyqxmd.com/read/29296018/prostate-cancer-radiation-and-urethral-strictures-a-systematic-review-and-meta-analysis
#7
Mohannad A Awad, Thomas W Gaither, E Charles Osterberg, Gregory P Murphy, Nima Baradaran, Benjamin N Breyer
BACKGROUND: We performed a systematic review and meta-analysis to determine the prevalence and predictors of urethral stricture development post radiation therapy (RT) for prostate cancer (PCa). METHODS: Published articles in PubMed/Medline, Cochrane, and Embase databases from January 2000 to April 2016 were queried. Inclusion criteria were any study that reported the prevalence of urethral strictures following external beam radiation therapy (EBRT), brachytherapy (BT), or both as a primary treatment for PCa...
January 2, 2018: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/29288007/overexpression-of-semaphorin-3a-in-patients-with-urothelial-cancer
#8
Zahava Vadasz, Jacob Rubinstein, Jacob Bejar, Hilla Sheffer, Sarel Halachmi
OBJECTIVE: A highly sensitive and specific urine marker for the detection of recurrent urothelial cancer and for screening healthy population or people at risk for urothelial cancer has not been found yet. As urine cytology is not sensitive enough, patients with non-muscle-invasive bladder cancer need lifelong follow-up involving multiple invasive cystoscopies. Our aims of study were to examine the expression of semaphorin 3A in urothelial cancer patients and to evaluate semaphorin 3A as a potential marker for urothelial cancer...
December 26, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29277656/unmasking-of-urinary-pubic-symphysis-fistula-upf-after-implantation-of-artificial-urinary-sphincter-in-prostate-cancer-survivors-user-beware-url-d-17-02187
#9
Arman A Kahokehr, Andrew C Peterson
OBJECTIVE: To describe the dramatic and rapid unmaking of Urinary pubic symphysis fistula and chronic osteomyelitis (UPF) following artificial urinary sphincter implantation (AUS). This has never been reported as UPF is usually an insidious sequelae of radiotherapy/energy ablation for prostate cancer (PCa). METHODS: We prospectively identified men who underwent rapid clinical decline due to UPF soon after AUS implantation at our institution in the previous 24 months...
December 22, 2017: Urology
https://www.readbyqxmd.com/read/29241706/placement-of-an-absorbable-rectal-hydrogel-spacer-in-patients-undergoing-low-dose-rate-brachytherapy-with-palladium-103
#10
Amandeep S Taggar, Tomer Charas, Gil'ad N Cohen, Keeratikarn Boonyawan, Marisa Kollmeier, Sean McBride, Nitin Mathur, Antonio L Damato, Michael J Zelefsky
PURPOSE: Rates of rectal toxicity after low-dose-rate (LDR) brachytherapy for prostate cancer are dependent on rectal dose, which is associated with rectal distance from prostate and implanted seeds. Placement of a hydrogel spacer between the prostate and rectum has proven to reduce the volume of the rectum exposed to higher radiation dose levels in the setting of external beam radiotherapy. We present our findings with placing a rectal hydrogel spacer in patients following LDR brachytherapy, and we further assess the impact of this placement on dosimetry and acute rectal toxicity...
December 11, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29239812/dosimetric-impact-of-inter-observer-catheter-reconstruction-variability-in-ultrasound-based-high-dose-rate-prostate-brachytherapy
#11
Alexandru Nicolae, Jure Murgic, Ivan Kruljac, Lior Dubnitzky, Laura D'Alimonte, Lin Lu, Aaron Cumal, Niki Law, Gerard Morton, Andrew Loblaw, Hans T Chung, Ananth Ravi
PURPOSE: To investigate the dosimetric impact of interobserver catheter reconstruction variability in transrectal ultrasound-guided prostate high-dose-rate (HDR) brachytherapy. METHODS AND MATERIALS: Twenty consecutive patients with intermediate- or high-risk prostate cancer were treated with a single, 15-Gy HDR brachytherapy boost as part of this study. The treated plan was used as the study reference plan (PR). Three expert treatment planners (observers) manually reconstructed the catheter paths on the static three-dimensional transrectal ultrasound images, and new plans were generated from the updated positions (POBS); subsequently, the dwell time and positions from the POBS plans were superimposed on the PR catheter paths to evaluate the dosimetric effect of the interobserver variations (PEVAL)...
November 24, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29225870/prostate-cancer-infiltrating-the-bladder-sphincter-successfully-treated-with-electrochemotherapy-a-case-report
#12
Nina Klein, Enric Gunther, Stefan Zapf, Rachid El-Idrissi, Johannes Atta, Michael Stehling
We demonstrate feasibility and safety of Electrochemotherapy for treatment of a prostate cancer (PCa) with infiltration of the urethral sphincter. The patient remained continent and potent, toxicity was low, and 6 months of follow-up showed no cancer activity. We conclude that Electrochemotherapy should be further evaluated as treatment strategy for locally advanced PCa.
December 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29211407/long-term-results-of-the-implantation-of-the-ams-800-artificial-sphincter-for-post-prostatectomy-incontinence-a-single-center-experience
#13
Carlos Alberto Ricetto Sacomani, Stênio de Cássio Zequi, Walter Henriques da Costa, Bruno Santos Benigno, Rodrigo Sousa Madeira Campos, Wilson Bachega, Gustavo Cardoso Guimarães
OBJECTIVES: Report the long-term outcomes of the AMS 800 artificial sphincer (AS) for the treatment post-prostatectomy incontinence (PPI) in a single center in Brazil. MATERIALS AND METHODS: Clinical data from patients who underwent the procedure were retrieved from the medical records of individuals with more than 1 year of follow-up from May 2001 to January 2016. Continence status (number of pads that was used), complications (erosion or extrusion, urethral atrophy, and infection), malfunctions, and need for secondary implantation were evaluated...
December 7, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29211405/high-intensity-focused-ultrasound-hifu-as-salvage-therapy-for-radio-recurrent-prostate-cancer-predictors-of-disease-response
#14
Shawn Dason, Nathan C Wong, Christopher B Allard, Jen Hoogenes, William Orovan, Bobby Shayegan
BACKGROUND: Some men with localized radio-recurrent prostate cancer may benefit from salvage high-intensity focused ultrasound (HIFU). Herein, we describe oncologic outcomes and predictors of disease response after salvage whole gland HIFU from our prospective cohort. MATERIALS AND METHODS: Patients with localized radio-recurrent prostate cancer were prospectively enrolled from January 2005 to December 2014. Participants had to meet both biochemical and histological definitions of recurrence...
December 7, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29201511/robot-assisted-radical-perineal-prostatectomy-first-experience-of-15-cases
#15
Volkan Tuğcu, Oktay Akça, Abdulmuttalip Şimşek, İsmail Yiğitbaşı, Selçuk Şahin, Ali İhsan Taşçı
Objective: Minimally invasive techniques are increasingly evolving and preferred to reduce surgical induced morbidity and mortality and minimize the challenges of surgical techniques. Especially radical perineal prostatectomy (RPP) includes some challenges like working in a deep and narrow space and challenging ergonomics for the surgeons. Because of these issues open RPP is still performed in experienced centers. In order to reduce these difficulties, robot- assisted radical perineal prostatectomy (r-RPP) is developed...
December 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29193884/morphological-and-clinical-evaluation-of-prostatic-urethra-using-modified-sonourethrography-with-retrograde-jelly-injection
#16
Tomonori Minagawa, Hironori Daimon, Noriyuki Ogawa, Tetsuichi Saito, Toshiro Suzuki, Takahisa Domen, Takashi Nagai, Teruyuki Ogawa, Osamu Ishizuka
OBJECTIVE: Using modified sonourethrography (mSUG) with retrograde jelly injection to precisely measure the morphological characteristics of the prostatic urethra, we assessed prostatic urethral morphology associated with clinical parameters of benign prostatic hyperplasia (BPH). METHODS: BPH patients (n = 43) and control patients with localized prostate cancer (PC; n = 57) were imaged by mSUG before surgery. Using the seminal colliculus as a landmark, prostatic urethral angulation (PUA), sagittal urethral diameter, and anterior or posterior prostatic urethral length were measured...
November 29, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/29191643/incidence-of-stress-urinary-incontinence-following-posterior-urethroplasty-for-radiation-induced-urethral-strictures
#17
Paul H Chung, Paige Esposito, Hunter Wessells, Bryan B Voelzke
OBJECTIVES: To identify the frequency of de novo SUI after posterior excision and primary anastomotic (EPA) urethroplasty in patients with radiation-induced urethral strictures (RIUS) and compare to patients with pelvic fracture urethral injuries (PFUI). METHODS: A retrospective review was conducted among patients who underwent successful posterior EPA urethroplasty between 2008 and 2016 for RIUS from prostate cancer or PFUI from blunt trauma. Only patients with an intact bladder neck on imaging were included...
November 27, 2017: Urology
https://www.readbyqxmd.com/read/29175892/interrupted-versus-continuous-suturing-for-vesicourethral-anastomosis-during-radical-prostatectomy-protocol-for-a-systematic-review-and-meta-analysis
#18
Karl Friedrich Kowalewski, Christian Tapking, Svetlana Hetjens, Felix Nickel, Philipp Mandel, Manuel Ritter, Maximilian Christian Kriegmair
INTRODUCTION: Radical prostatectomy is the mainstay of treatment for prostate cancer. The vesicourethral anastomosis is a critical step, which most likely impacts urinary continence and urethral stenosis. To date, it still remains unclear whether interrupted and continuous suturing for the anastomosis have different outcomes. Therefore, the aim of this systematic review and meta-analysis is to compare different suture techniques for vesicourethral anastomosis in terms of surgical and functional parameters...
November 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/29171166/outcomes-of-asian-patients-with-localized-prostate-cancer-treated-with-combined-intensity-modulated-radiation-therapy-imrt-and-high-dose-rate-hdr-brachytherapy-a-single-institution-experience
#19
Ivy Wei Shan Ng, Jeremy Chee Seong Tey, Yu Yang Soon, Michelle Shu Fen Tseng, Desiree Chen, Keith Hsiu Chin Lim
AIM: External beam radiotherapy (EBRT) followed by high dose rate (HDR) brachytherapy boost has demonstrated minimal toxicities and improved disease control rate compared with EBRT alone in observational and randomized studies with predominantly Caucasian patients. This study aims to report the outcomes of patients treated with this approach in our predominantly Asian population. METHODS: Medical records for patients with localized prostate cancer who received combined EBRT delivered via intensity modulated radiotherapy (IMRT) technique followed by HDR brachytherapy boost were retrospectively reviewed...
November 23, 2017: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29169450/orthotopic-urinary-diversion-for-women
#20
REVIEW
Dimitar V Zlatev, Eila C Skinner
Orthotopic neobladder is a viable option for women undergoing cystectomy for bladder cancer, with excellent oncologic outcomes and a low incidence of urethral recurrence. Careful patient selection is important, as is developing a clear understanding by the patient and her family in what to expect with an orthotopic diversion. Surgical technique is also important in optimizing functional outcomes, such as continence, sexual function, and decreased rate of vaginal fistula formation, and urinary retention.
February 2018: Urologic Clinics of North America
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