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https://www.readbyqxmd.com/read/29925637/interrogation-of-nonconserved-human-adipose-lincrnas-identifies-a-regulatory-role-of-linc-adal-in-adipocyte-metabolism
#1
Xuan Zhang, Chenyi Xue, Jennie Lin, Jane F Ferguson, Amber Weiner, Wen Liu, Yumiao Han, Christine Hinkle, Wenjun Li, Hongfeng Jiang, Sager Gosai, Melanie Hachet, Benjamin A Garcia, Brian D Gregory, Raymond E Soccio, John B Hogenesch, Patrick Seale, Mingyao Li, Muredach P Reilly
Long intergenic noncoding RNAs (lincRNAs) have emerged as important modulators of cellular functions. Most lincRNAs are not conserved among mammals, raising the fundamental question of whether nonconserved adipose-expressed lincRNAs are functional. To address this, we performed deep RNA sequencing of gluteal subcutaneous adipose tissue from 25 healthy humans. We identified 1001 putative lincRNAs expressed in all samples through de novo reconstruction of noncoding transcriptomes and integration with existing lincRNA annotations...
June 20, 2018: Science Translational Medicine
https://www.readbyqxmd.com/read/29909357/abdominal-muscle-recruitment-and-its-effect-on-the-activity-level-of-the-hip-and-posterior-thigh-muscles-during-therapeutic-exercises-of-the-hip-joint
#2
Sharon M H Tsang, Amanda H M Lam, Melody H L Ng, Kiki W K Ng, Cherry O H Tsui, Benjamin Yiu
Abdominal exercise has been advocated to improve the protection of the spine and neuromuscular efficiency of the limb movements. The purpose of this study was to examine the effect of enhanced contraction of internal oblique and transversus abdominis (IO/TrA) on the activity level of the hip and posterior thigh muscles during therapeutic hip exercises. Twenty healthy females were required to perform eight hip exercises under two conditions, natural versus enhanced IO/TrA contraction conditions. Muscle activity of gluteus maximus, gluteus medius, tensor fasciae latae and biceps femoris of the exercising leg was measured by surface electromyography during hip exercises, and expressed in percentage normalized to the maximal voluntary isometric contraction (%MVIC)...
June 12, 2018: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29787513/real-time-ultrasound-assisted-gluteal-fat-grafting
#3
Alvaro Luiz Cansancao, Alexandra Condé-Green, Rafael A Vidigal, Ricardo Luis Rodriguez, Richard A D'Amico
BACKGROUND: Outcomes in primary breast augmentation depend on careful preoperative planning and clear communication between patient and surgeon. Three-dimensional imaging with computer simulation is an evolving technology with the potential to enhance the preoperative consultation for patients considering primary breast augmentation. The purpose of this study was to prospectively evaluate the impact of three-dimensional imaging with computer simulation on patient-reported and objective, mammometric outcomes in women undergoing primary breast augmentation...
May 16, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29707455/bilateral-sciatic-neuropathy-following-gluteal-augmentation-with-autologous-fat-grafting
#4
Vasileios Vasilakis, Malack Hamade, Steven A Stavrides, Thomas A Davenport
As gluteal augmentation continues to gain in popularity among patients seeking aesthetic enhancements, a thorough knowledge of the postoperative complications associated with this procedure is crucial. This case report concerns a 31-year-old woman who suffered bilateral foot drop secondary to sciatic neuropathy and as a result was wheelchair-bound for several months, following gluteal autologous fat grafting in the Dominical Republic. One year later, the patient had persistent left foot drop and sensory deficits...
March 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29572323/evaluation-of-collateral-source-characteristics-with-3-dimensional-analysis-using-micro-x-ray-computed-tomography
#5
Yuichiro Arima, Seiji Hokimoto, Noriaki Tabata, Osamu Nakagawa, Asahi Oshima, Yosuke Matsumoto, Takahiro Sato, Toshifumi Mukunoki, Jun Otani, Masanobu Ishii, Michie Uchikawa, Eiichiro Yamamoto, Yasuhiro Izumiya, Koichi Kaikita, Hisao Ogawa, Koichi Nishiyama, Kenichi Tsujita
BACKGROUND: Collateral arteries provide an alternative blood supply and protect tissues from ischemic damage in patients with peripheral artery disease. However, the mechanism of collateral artery development is difficult to validate. METHODS AND RESULTS: Collateral arteries were visualized using micro-x-ray computed tomography. Developmental characteristics were assessed using confocal microscopy. We conducted a single-center, retrospective, observational study and assessed the dilatation of collateral arteries on ischemic sides...
March 23, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29519496/autologous-gluteal-augmentation-with-the-moustache-transposition-flap-technique
#6
REVIEW
Robert F Centeno
Massive weight loss patients and aesthetic patients can present with significant gluteal contour abnormalities. Gluteal ptosis, skeletal deformities, severe platypgia, and a paucity of donor fat for autologous transfer are common problems. Excisional procedures are used to treat massive-weight-loss contour abnormalities. These procedures present an opportunity to address severe gluteal deformities using autologous tissue augmentation. With a working knowledge of the relevant anatomy, sound surgical technique, and meticulous postoperative care, autologous gluteal autoaugmentation with circumferential body lift/excisional buttock lift using the "Moustache" flap technique will enhance massive weight loss body contouring outcomes and improve patient satisfaction...
April 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29519494/autologous-flap-gluteal-augmentation-purse-string-technique
#7
REVIEW
Joseph P Hunstad, Mark A Daniels, John C Crantford
The ideal patient for purse-string gluteoplasty has buttock deflation and ptosis, and wishes to improve projection. Key elements of the procedure are buttock lifting combined with auto-augmentation, no undermining of auto-augmentation tissue, and use of a purse-string suture to enhance projection of auto-augmentation tissue. Purse-string gluteoplasty is a safe and effective technique to correct buttock ptosis and atrophy.
April 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29519485/classification-system-for-gluteal-evaluation-revisited
#8
REVIEW
Constantino G Mendieta, Aditya Sood
The buttock area has received much media attention in recent years, which has produced increased patient demand for buttock reshaping or contouring and augmentation. Increasing patient demand has necessitated a more structured approach to evaluation of gluteal anatomy and the development of surgical procedures to enhance its beauty.
April 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29502131/clinical-radiological-and-pathological-features-of-extraskeletal-osteosarcoma
#9
Lauren A Roller, Ivan Chebib, Miriam A Bredella, Connie Y Chang
OBJECTIVE: To evaluate clinical and radiological features of pathology-proven extraskeletal osteosarcomas. METHODS: This retrospective study was IRB-approved and HIPAA-compliant. Our pathology database was queried for cases of extraskeletal osteosarcoma. Tumor location, size, imaging appearance, presence of metastases, and clinical outcome were documented. RESULTS: Nineteen patients met inclusion criteria (age 59 ± 15 (range 28-85) years; 15 male, 4 female)...
March 3, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29373449/soft-tissue-structures-differ-in-patients-with-prearthritic-hip-disease
#10
Anne Le Bouthillier, Kawan S Rakhra, Etienne L Belzile, Ryan C B Foster, Paul E Beaulé
BACKGROUND: Clinically, understanding how the soft tissue envelope adapts to various forms of hip dysfunction could enhance both surgical and nonsurgical management. Very few studies have looked at soft tissue structures as preoperative discriminators between varying underlying etiologies of hip conditions. PURPOSE: To demonstrate that the magnetic resonance arthrography assessment of soft tissue structures of the hip will preoperatively differ in patients with different underlying hip joint diseases...
February 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29369983/gluteal-augmentation-and-enhancement-of-the-female-silhouette-analysis-and-technique
#11
Constantino Mendieta, James M Stuzin
Dr. Constantino Mendieta demonstrates and details his personal technique for gluteal augmentation. The video demonstration is divided into three parts: Part I, Aesthetic Analysis and Preoperative Marking; Part II, Creating the Female Silhouette with Circumferential Lipoplasty; and Part III, Autogenous Gluteal Augmentation. Artistic concepts for gluteal augmentation and contouring the female silhouette and technical considerations for patient safety are emphasized. This Master Series Video article is the first in a planned series of video vignettes...
February 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29351135/angiography-and-embolization-in-the-management-of-bleeding-pelvic-fractures
#12
Rahul Vaidya, Jacob Waldron, Alesha Scott, Kerellos Nasr
The use, timing, and priority of angioembolization in the management of bleeding pelvic fractures remain ambiguous. The most common vessels for angioembolization are, in decreasing order, the internal iliac artery and its branches, the superior gluteal artery, the obturator artery, and the internal pudendal artery. Technical success rates for this treatment option range from 74% to 100%. The fracture patterns most commonly requiring angioembolization are the Young and Burgess lateral compression and anterior-posterior compression types and Tile type C...
February 15, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29239140/acquired-myospherulosis-secondary-to-gluteal-augmentation-on-fine-needle-aspiration-cytology-a-diagnostic-challenge
#13
Susan Alperstein, Thomas Dilcher, Kartik Viswanathan, Rema A Rao, Momin T Siddiqui, Tamara Giorgadze
A 30-year-old female presented with a three-month history of a multilocular cystic lesion over the lumbosacral spine. Fine-needle aspiration biopsy (FNA) of the lesion was performed at an outside institution, and a cytologic diagnosis, suspicious for chordoma, was rendered. The patient presented for surgical consultation at our institution. Repeat FNA demonstrated an unusual fat-like material. Upon further inquiry, the patient provided a recent history of gluteal contour improvement with fibroadipose tissue implants...
May 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29206970/thrombospondin-1-and-disease-progression-in-dysferlinopathy
#14
Norifumi Urao, Rita E Mirza, Thomas F Corbiere, Zsuzsanna Hollander, Christoph H Borchers, Timothy J Koh
The purpose of this study was to determine whether thrombospondin (TSP)-1 promotes macrophage activity and disease progression in dysferlinopathy. First, we found that levels of TSP-1 are elevated in blood of non-ambulant dysferlinopathy patients compared with ambulant patients and healthy controls, supporting the idea that TSP-1 levels are correlated with disease progression. We then crossed dysferlinopathic BlaJ mice with TSP-1 knockout mice and assessed disease progression longitudinally with magnetic resonance imaging (MRI)...
December 15, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/29016479/the-effects-of-foam-rolling-as-a-recovery-tool-in-professional-soccer-players
#15
Ezequiel Rey, Alexis Padrón-Cabo, Pablo B Costa, Roberto Barcala-Furelos
Foam rolling (FR) is a common strategy used after training and competition by players. However, no previous studies have assessed the effectiveness of FR as recovery tool in sports populations. The aim of this study was to examine the effectiveness of FR (20 minutes of foam rolling exercises on quadriceps, hamstrings, adductors, gluteals, and gastrocnemius) and passive recovery (20 minutes sit on a bench) interventions performed immediately after a training session on Total Quality Recovery (TQR), perceived muscle soreness, jump performance, agility, sprint, and flexibility 24 hours after the training...
October 7, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28992020/rapid-communication-dietary-selenium-improves-skeletal-muscle-mitochondrial-biogenesis-in-young-equine-athletes
#16
S H White, S Wohlgemuth, C Li, L K Warren
Exercise is known to promote mitochondrial biogenesis in skeletal muscle as well as enhance mitochondrial function and efficiency in human and rodent models. These adaptations help to decrease exercise-associated production of reactive oxygen species, which can negatively affect health and performance if antioxidant mechanisms are overwhelmed. Little is known about the adaptations of mitochondria in response to exercise training in the growing horse or if supplementation with a dietary antioxidant can improve mitochondrial function...
September 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28980278/do-we-need-retarded-delivery-of-bone-growth-factors-in-facial-bone-repair-an-experimental-study-in-rats
#17
N Moser, N Lohse, J Golstein, P Kauffmann, B Sven, M Epple, H Schliephake
The aim of the present study was to evaluate the effect of different dosages of retarded vs. rapid release of bone morphogenic protein 2 (BMP2) at different recipient sites. Porous composite poly(D,L-lactic acid) (PDLLA)/CaCO3 scaffolds were loaded with three different dosages of rhBMP2 (24 µg, 48 µg and 96 µg) and implanted, together with blank controls, both into non-healing defects of the mandibles and into the gluteal muscles of 24 adult male Wistar rats. After 26 weeks, bone formation and expression of bone specific markers [alkaline phosphatase (AP) and Runx2] were evaluated by histomorphometry and immunohistochemistry...
October 5, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28963047/first-case-of-2-synchronous-gluteal-arteries-aneurysms-treated-by-endovascular-plug-embolization-case-report-and-literature-review
#18
Andrea Esposito, Danilo Menna, Matteo Salcuni, Ferdinando Di Leo, Pietro Benedetto, Antonio Trani, Antonino Pierluigi Cappiello
INTRODUCTION: Gluteal artery aneurysms (GAAs) are rare, accounting for less than 1% of all arterial aneurysms. Most of them are post-traumatic in nature and involve the superior gluteal artery (SGA), while injuries of the inferior gluteal artery (IGA) have been reported less frequently. We report an unusual case of a patient with double saccular GAA of unknown etiology, involving both the SGA and IGA, successfully treated by endovascular embolization. CASE REPORT: A 80-year-old man referred to our hospital complaining of the progressive onset of left buttock pain and swelling exacerbated by sitting position in the last 4 months...
February 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28936783/experimental-variation-of-the-level-and-the-ratio-of-angiogenic-and-osteogenic-signaling-affects-the-spatiotemporal-expression-of-bone-specific-markers-and-organization-of-bone-formation-in-ectopic-sites
#19
Norman Moser, Jan Goldstein, Phillip Kauffmann, Matthias Epple, Henning Schliephake
OBJECTIVES: The aim of the present study was to test the hypothesis that the ratio of angiogenic and osteogenic signaling affects ectopic bone formation when delivered in different amounts. MATERIALS AND METHODS: Porous composite PDLLA/CaCO3 scaffolds were loaded with rhBMP2 and rhVEGF in different dosage combinations and implanted into the gluteal muscles of 120 adult male Wistar rats. Bone formation and expression of alkaline phosphatase and Runx2 were quantified by histomorphometry...
April 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28900560/building-a-better-gluteal-bridge-electromyographic-analysis-of-hip-muscle-activity-during-modified-single-leg-bridges
#20
B J Lehecka, Michael Edwards, Ryan Haverkamp, Lani Martin, Kambry Porter, Kailey Thach, Richard J Sack, Nils A Hakansson
BACKGROUND: Gluteal strength plays a role in injury prevention, normal gait patterns, eliminating pain, and enhancing athletic performance. Research shows high gluteal muscle activity during a single-leg bridge compared to other gluteal strengthening exercises; however, prior studies have primarily measured muscle activity with the active lower extremity starting in 90 ° of knee flexion with an extended contralateral knee. This standard position has caused reports of hamstring cramping, which may impede optimal gluteal strengthening...
August 2017: International Journal of Sports Physical Therapy
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