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Evgeny V Khmelevsky, Irina N Kancheli, Vladimir S Khoroshkov, Andrey D Kaprin
Aim: This study evaluated the frequency and long-term dynamics of early and late post irradiation damage after proton-photon or photon therapy for locally advanced prostate cancer. Background: The results of a randomized study of proton-photon or photon therapy using several fractionation regimes were analyzed in 272 patients with high and intermediate risk of progression. Materials and methods: Three variants of proton boost fractionation were studied sequentially: 3...
January 2018: Reports of Practical Oncology and Radiotherapy
A Fabre-Baudouin, A L Roux, C Marin, M Lachatre, M De Laroche, M Ponsoye, T Hanslik, S Trad
INTRODUCTION: Lymphogranuloma venereum (LG) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis L serovar. METHODS: These five consecutive cases aim to highlight the risk of LG misdiagnosis, in case of initial presentation with isolated inguinal adenitis. RESULTS: Five men (mean age: 30±7 years) were seen in an internal medicine department, for inguinal adenopathy. One patient had clinical signs of urethritis. None presented an associated rectitis...
December 2017: La Revue de Médecine Interne
C M Martínez-Arribas, C González-San Segundo, P Cuesta-Álvaro, F A Calvo-Manuel
OBJECTIVE: To determine rectal and urinary toxicity after external beam radiation therapy (EBRT), assessing the results of patients who undergo radical or postoperative therapy for prostate cancer (pancreatic cancer) and their correlation with potential risk factors. METHOD: A total of 333 patients were treated with EBRT. Of these, 285 underwent radical therapy and 48 underwent postoperative therapy (39 cases of rescue and 9 of adjuvant therapy). We collected clinical, tumour and dosimetric variable to correlate with toxicity parameters...
December 2017: Actas Urologicas Españolas
Gustavo Arruda Viani, Aline Sakamoto
PURPOSE: The aim of this quasi-experimental study is to evaluate a novel technique for an outpatient application of formalin for chronic rectal bleeding after prostate irradiation. METHODS: This is a quasi- experimental clinical trial developed between January 2010 and July 2015, including 35 patients with chronic radiation rectitis (CRP) due to a previous prostate radiation course. The study's eligibility was (1) completed external beam radiation therapy for prostate carcinoma >6 months previously, (2) rectal bleeding, defined as a frequency of >1× per week and/or needing of blood transfusions, and (3) diagnosis of chronic proctitis at colonoscopy...
July 2017: International Journal of Colorectal Disease
Dine Koriche, Corinne Gower-Rousseau, Charbel Chater, Alain Duhamel, Julia Salleron, Noémie Tavernier, Jean-Frédéric Colombel, Benjamin Pariente, Antoine Cortot, Philippe Zerbib
INTRODUCTION: Crohn's disease (CD) is a progressive inflammatory disease affecting the entire gastrointestinal tract. The need for a definitive stoma (DS) is considered as the ultimate phase of damage. It is often believed that the risk of further disease progression is small when a DS has been performed. AIMS: The goals of the study were to establish the rate of CD recurrence above the DS and to identify predictive factors of CD recurrence at the time of DS. METHODS: We retrospectively reviewed all medical records of consecutive CD patients having undergone DS between 1973 and 2010...
April 2017: International Journal of Colorectal Disease
Yazid Belkacemi, Laurianne Colson-Durand, Adeline Granzotto, Shan Husheng, Nhu Hanh To, Soufya Majdoul, Saada Guet, Marie-Laure Hervé, Gloria Fonteneau, Christian Diana, Cindy Le Bret, Claude Dominique, Maryse Fayolle, Nicolas Foray
PURPOSE: After radiation therapy (RT), various radiation-induced toxicities can develop in about one-fourth of patients. An international interest in using morbidity and mortality rates to monitor the quality of care and integrate morbidity and mortality review (MMR) meetings into organizations' governance processes has arisen. We report the first results of patients included in our MMR procedure that included biological assays for individual intrinsic radiosensitivity (IIRS). METHODS AND MATERIALS: Twenty-three patients were prospectively included in the MMR database...
November 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Anna Boladeras, Evelyn Martinez, Ferran Ferrer, Cristina Gutierrez, Salvador Villa, Joan Pera, Ferran Guedea
AIMS AND BACKGROUND: To present survival and toxicity outcomes in patients with clinically localized, non-metastatic prostate cancer (PCa) treated with external beam radiotherapy (EBRT) combined with androgen deprivation therapy (ADT). MATERIALS AND METHODS: Retrospective study of 849 PCa patients (pts) treated from 1996 to 2005. Until August 2000, all patients (281) were treated with conventional dose EBRT (<76 Gy); subsequent pts received ≥76 Gy (565 pts)...
May 2016: Reports of Practical Oncology and Radiotherapy
Yu Zhang, Ping-Wu Zhao, Gang Feng, Gang Xie, An-Qun Wang, Yong-Hong Yang, Dong Wang, Xiao-Bo Du
The aims of this study were to simultaneously evaluate the expression of Y-box binding protein-1 (YB-1) in non-neoplastic rectal tissue and rectal cancer tissue, and to collect clinical follow-up data for individual patients. Additionally, we aimed to investigate the developmental functions and prognostic value of YB-1 in rectal cancer. We performed immunohistochemical studies to examine YB-1 expression in tissue samples from 80 patients with rectal cancer, 30 patients with rectal tubular adenoma, and 30 patients with rectitis...
2015: PloS One
Neşe Kiremit-Korkut, Cağatay Korkut, Hatice Bilge
BACKGROUND: Radiation rectitis is a major problem associated with high-doseirradiation used for pelvic malignancies. OBJECTIVE: The aim of this study was to investigate the possible protectiveeffect of mesalamine against irradiation-induced oxidative tissue damage in an experimental model. METHODS: THREE GROUPS OF FEMALE SPRAGUE DAWLEY RATS WERE ASSIGNED TO RECEIVE TREATMENT AS FOLLOWS: mesalamine enema (60 mg/mL) BID + irradiation (IR) was given to the mesalamine + IR group, and isotonic saline enema BID + irradiation to the control group...
September 2004: Current Therapeutic Research, Clinical and Experimental
Hajime Ushigome, Tetsushi Hayakawa, Mamoru Morimoto, Hidehiko Kitagami, Moritsugu Tanaka
We report a very rare case of rectal arteriovenous fistula following sigmoidectomy and discuss this case in the context of the existing literature. In April 2011, the patient, a man in his 60s, underwent laparoscopic sigmoidectomy with lymph node dissection for sigmoid colon cancer. Beginning in February 2012, he experienced frequent diarrhea. Abdominal contrast-enhanced CT revealed local thickening of the rectal wall and rectal arteriovenous fistula near the anastomosis site. Rectitis from the rectal arteriovenous fistula was diagnosed...
January 2014: Asian Journal of Endoscopic Surgery
Airton Mota Moreira, Carlos Frederico Sparapan Marques, Alberto Azoubel Antunes, Caio Sergio Rizkallah Nahas, Sérgio Carlos Nahas, Miguel Ángel de Gregorio Ariza, Francisco Cesar Carnevale
Prostatic artery embolization (PAE) is an alternative treatment for benign prostatic hyperplasia. Complications are primarily related to non-target embolization. We report a case of ischemic rectitis in a 76-year-old man with significant lower urinary tract symptoms due to benign prostatic hyperplasia, probably related to nontarget embolization. Magnetic resonance imaging revealed an 85.5-g prostate and urodynamic studies confirmed Inferior vesical obstruction. PAE was performed bilaterally. During the first 3 days of follow-up, a small amount of blood mixed in the stool was observed...
December 2013: Cardiovascular and Interventional Radiology
Jian-Hong Fu, Zhan Gao, Chen-Chen Ren, Yong-Gang Shi
A total of 285 patients with stage Ib2 and IIa2 cervical cancer were categorized into three groups, and received preoperative neoadjuvant chemotherapy combined with vaginal intracavitary irradiation, neoadjuvant chemotherapy alone or radiotherapy, respectively. The effective rate of 70.6 % in group 1 was much higher than 41.4% in group 2 (P=0.000) and 46.9 % in group 3 (P=0.000); The percentage of patients receiving postoperative adjuvant therapy was 44.1% in group 1, much lower than 67.8% in group 2 (P=0.001) and 64...
2013: Asian Pacific Journal of Cancer Prevention: APJCP
(no author information available yet)
The aim was to evaluate the effectiveness of various fractionation proton boost in the proton-photon radiation therapy of locally advanced prostate. The study included 272 patients with prostate cancer and high-intermediate risk of progression. 114 patients received 3-D conformal local irradiation of the prostate by proton beam 220Mev. The focal dose of 28-28,8 SoGy-eq was fed to the prostate for 8, 5 or 3 fractions for 3, 4 or 5.5 Gy-eq respectively. Given the photon component (44 Gy in 22 fractions to the whole volume of the pelvis), the dose to the prostate was 72...
2012: Voprosy Onkologii
J Egea Valenzuela, F Alberca de las Parras, F Carballo Álvarez, J Molina Martínez
No abstract text is available yet for this article.
February 2011: Revista Española de Enfermedades Digestivas
Na Wang, Quan-Lin Guan, Kai Wang, Xin Zhou, Chen Gao, Han-Teng Yang, Tian-Gen Ni
OBJECTIVE: The objectives of this review are to compare the effectiveness and safety of radiochemotherapy (RTCT) with radiotherapy (RT) alone in locally advanced cervical cancer (LACC). DATA SOURCES: We comprehensively searched the Cochrane library, Medline, EMBASE, Chinese biomedicine literature database, Chinese scientific full-text database and Chinese journal full-text database for relevant articles. The computer search was supplemented with a manual search of reference lists for all available review articles...
January 2011: Archives of Gynecology and Obstetrics
M-P Massoure, P Sockeel, M Richecoeur, A-S Lipovac, J-A Bronstein
We report a 38-year-old immunocompetent patient who presented with a neutropenic rectitis after a treatment by amoxicillin for nasopharyngitis. Neutropenic colitis is a digestive wall inflammation, preferentially localized in the ileo-caecal area and the right colon, which leads to necrosis and sepsis, and usually occurs in neutropenic patients treated by chemotherapy with an incidence of 6%. It is a serious and often lethal disease. The treatment is supportive, and surgery is limited to the occurrence of complications (perforation, bleeding)...
December 2009: La Revue de Médecine Interne
J M Pelgrom, D Vogelaers, I Colle
Five Human Immunodeficiency Virus (HIV) seropositive homosexually active men experienced hepatitis C-seroconversion in the period between September 2004 and January 2007 at a single HIV Reference Center (University Hospital Ghent, Belgium). There was no history of intravenous drug use. All had unprotected anal sex with multiple other HIV seropositive men in the recent past. All of them had clinical syphilis and/or lymphogranuloma venereum rectitis within three to six months before the hepatitis C-seroconversion was detected...
September 2008: Acta Clinica Belgica
M Untereiner, S Renard-Oldrini, H Mecellem, D Burie, Y Lassen, R Ruchaud Phy, S Joseph Phy, L Harzee Phy
Exclusive radiotherapy is one of therapeutic standard in the curative treatment of localized prostate cancer. Results are equivalent when compared with other treatment regimens (radical prostatectomy or curietherapy) in localized forms. However, the patients risks profiles to predict noxious effects are different. Between 2005 and 2006, 27 patients have been treated with intensity modulated radiation therapy and image-guided radiotherapy (IGRT), after implantation of gold markers to target prostate localization during daily radiotherapy seances...
2008: Bulletin de la Société des Sciences Médicales du Grand-Duché de Luxembourg
Vincent de Parades, Pierre Bauer, Philippe Marteau, Laurent Chauveinc, Thierry Bouillet, Patrick Atienza
No abstract text is available yet for this article.
November 2007: Gastroentérologie Clinique et Biologique
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