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appendicitis, timing of treatment

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https://www.readbyqxmd.com/read/29889113/the-role-of-appendectomy-at-the-time-of-laparoscopic-surgery-for-benign-gynecologic-conditions
#1
Ann Peters, Suketu M Mansuria
PURPOSE OF REVIEW: The risk-benefit ratio of concurrent appendectomy at the time of gynecologic surgery has long been debated and remains controversial. However, emerging data on the appendix's role in chronic pain syndromes point to a previously unrecognized link between gynecologic disorders and appendicular pathology. In this article, we review the indications for appendectomy at the time of laparoscopic gynecologic surgery for the treatment of endometriosis and chronic pelvic pain...
June 7, 2018: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29764132/high-level-theoretical-characterization-of-the-vinoxy-radical-%C3%A2-ch-2-cho-o-2-reaction
#2
Jared D Weidman, Ryan T Allen, Kevin B Moore, Henry F Schaefer
Numerous processes in atmospheric and combustion chemistry produce the vinoxy radical (• CH2 CHO). To understand the fate of this radical and to provide reliable energies needed for kinetic modeling of such processes, we have examined its reaction with O2 using highly reliable theoretical methods. Utilizing the focal point approach, the energetics of this reaction and subsequent reactions were obtained using coupled-cluster theory with single, double, and perturbative triple excitations [CCSD(T)] extrapolated to the complete basis set limit...
May 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29738603/a-powerful-approach-to-the-study-of-moderate-effect-modification-in-observational-studies
#3
Kwonsang Lee, Dylan S Small, Paul R Rosenbaum
Effect modification means the magnitude or stability of a treatment effect varies as a function of an observed covariate. Generally, larger and more stable treatment effects are insensitive to larger biases from unmeasured covariates, so a causal conclusion may be considerably firmer if this pattern is noted if it occurs. We propose a new strategy, called the submax-method, that combines exploratory, and confirmatory efforts to determine whether there is stronger evidence of causality-that is, greater insensitivity to unmeasured confounding-in some subgroups of individuals...
May 8, 2018: Biometrics
https://www.readbyqxmd.com/read/29720238/two-versus-five-days-of-antibiotics-after-appendectomy-for-complex-acute-appendicitis-appic-study-protocol-for-a-randomized-controlled-trial
#4
Anne Loes van den Boom, Elisabeth M L de Wijkerslooth, Joost van Rosmalen, Frédérique H Beverdam, Evert-Jan G Boerma, Marja A Boermeester, Joanna W A M Bosmans, Thijs A Burghgraef, Esther C J Consten, Imro Dawson, Jan Willem T Dekker, Marloes Emous, Anna A W van Geloven, Peter M N Y H Go, Luc A Heijnen, Sander A Huisman, Dayanara Jean Pierre, Joske de Jonge, Jurian H Kloeze, Marc A Koopmanschap, Hester R Langeveld, Misha D P Luyer, Damian C Melles, Johan W Mouton, Augustinus P T van der Ploeg, Floris B Poelmann, Jeroen E H Ponten, Charles C van Rossem, Wilhelmina H Schreurs, Joël Shapiro, Pascal Steenvoorde, Boudewijn R Toorenvliet, Joost Verhelst, Hendt P Versteegh, Rene M H Wijnen, Bas P L Wijnhoven
BACKGROUND: Acute appendicitis is one of the most common indications for emergency surgery. In patients with a complex appendicitis, prolonged antibiotic prophylaxis is recommended after appendectomy. There is no consensus regarding the optimum duration of antibiotics. Guidelines propose 3 to 7 days of treatment, but shorter courses may be as effective in the prevention of infectious complications. At the same time, the global issue of increasing antimicrobial resistance urges for optimization of antibiotic strategies...
May 2, 2018: Trials
https://www.readbyqxmd.com/read/29707608/intestinal-perforation-after-surgical-treatment-for-incisional-hernia-iatrogenic-or-idiopathic
#5
V Amorosi, B Longo, M Sorotos, G Firmani, F D'Angelo, F Santanelli di Pompeo
Intestinal perforation (IP) is a life-threatening gastroenterological condition requiring urgent surgical care, which may present itself as an uncommon complication following incisional hernia repair surgery, most often because of iatrogenic traumatism occurring during the procedure. However, we report a case where a spontaneous onset can be hypothesised. A 60-years-old patient underwent repair of an abdominal laparocele, through rectus abdominis muscle plasty, 5 years after development of an incisional hernia due to exploratory laparotomy for the treatment of acute appendicitis...
2018: Case Reports in Plastic Surgery & Hand Surgery
https://www.readbyqxmd.com/read/29589454/-open-versus-laparoscopic-appendectomy-for-acute-appendicitis-in-children
#6
R Štichhauer, J Koudelka
INTRODUCTION: Acute appendicitis is a common disease affecting both adults and children. The basic therapeutic procedure is an appendectomy. Open appendectomy has been gradually supplemented and sometimes replaced by a laparoscopic approach in numerous departments. The aim of our work was to compare laparoscopic and open surgery objectively. METHOD: Retrospective analysis of data from patients operated on at the Department of Pediatric Surgery and Traumatology, Teaching Hospital in Hradec Králové in 20092016...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29529968/use-of-8-cm-22g-long-peripheral-cannulas-in-pediatric-patients
#7
Maurizio Pacilli, Catherine J Bradshaw, Simon A Clarke
INTRODUCTION: Medium-term intravenous access in children is normally achieved by means of repeated multiple peripheral intravenous cannula insertions or peripherally inserted central catheters. Long peripheral cannulas might offer an alternative to these devices in children. Our aim was to clarify whether long peripheral cannulas provide reliable medium-term intravenous access avoiding the need for multiple peripheral intravenous cannulations or peripherally inserted central catheter insertion in children undergoing surgery...
March 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29527849/how-prevalent-is-hydronephrosis-secondary-to-acute-appendicitis-a-cross-sectional-study
#8
Hanan Goldberg, Gil N Bachar, Riad Majadla, Ofer Yossepowitch, Jack Baniel, Edward Ram
BACKGROUND: Right hydronephrosis secondary to acute appendicitis is an under-reported phenomenon with only several case reports published. OBJECTIVES: To assess the incidence of this phenomenon in our database of patients diagnosed with acute appendicitis. METHODS: Data were collected on 1092 patients who underwent surgery due to acute appendicitis between 2003 and 2007 in our tertiary medical center. The data entailed demographic, surgical, and hospitalization parameters including ultrasound or computed tomography examinations and presence of right hydronephrosis prior to surgery...
March 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29521805/the-alvarado-score-should-be-used-to-reduce-emergency-department-length-of-stay-and-radiation-exposure-in-select-patients-with-abdominal-pain
#9
Jamie J Coleman, Bryan W Carr, Tyrone Rogers, Matthew S Field, Ben L Zarzaur, Stephanie A Savage, Peter M Hammer, Brian L Brewer, David V Feliciano, Grace S Rozycki
BACKGROUND: Abdominal pain is the common reason patients seek treatment in emergency departments (ED), and computed tomography (CT) is frequently used for diagnosis; however, length of stay (LOS) in the ED and risks of radiation remain a concern. The hypothesis of this study was the Alvarado score (AS) could be used to reduce CT scans and decrease ED LOS for patients with suspected acute appendicitis (AA). METHODS: A retrospective review of patients who underwent CT to rule out AA from January 1, 2015, to December 31, 2015, was performed...
June 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29419955/-predictive-factors-of-gangrenous-post-appendectomy-intra-abdominal-abscess-a-case-control-study
#10
J Serradilla, A Bueno, C De la Torre, E Domínguez, A Sánchez, B Nava, M Álvarez, M López Santamaría, L Martínez
BACKGROUND: Acute appendicitis is the most frequent surgical urgency in children. Frequently, it can be complicated with an intraabdominal abscess that will require a longer and expensive treatment. Our aim is to know if it is possible to predict this complication before its beginning. MATERIAL AND METHODS: Retrospective case-control study with patients treated between 2011 and 2016, paired according to their own characteristics (age, sex and weight), clinical aspects (symptoms, time of their onset, physical examination) and type of appendicitis (gangrenous)...
February 1, 2018: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/29393074/laparoscopic-appendectomy-for-the-treatment-of-acute-appendicitis-a-single-center-experience
#11
Giuseppe Carbotta, Antonella Del Vecchio, Antonio Prestera, Rita Laforgia, Maria Grazia Sederino, Giovanni Casamassima, Marina Minafra, Salvatore Fedele, Giovanni Balducci, Nicola Palasciano
AIM: The aim of our study is to compare the pre, intra- and post-operative variables of the two surgical techniques, to demonstrate if laparoscopic appendectomy can be considered safer and associated to better outcome. MATERIAL OF STUDY: A retrospective analysis of 175 patients has been carried out. Alvarado score, time of surgery, analgesic therapy and length of hospital stay calculated. Finally, postoperative complications were recorded. RESULTS: From January 2011 - April 2016 175 patients were enrolled: 128pts underwent laparoscopic technique and 47pts open technique...
January 31, 2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29344678/conservative-antibiotic-treatment-for-acute-uncomplicated-appendicitis-is-feasible
#12
Zvi Steiner, Genady Buklan, Michael Gutermacher, Ita Litmanovitz, Tal Landa, Shmuel Arnon
PURPOSE: Appendectomy versus conservative antibiotic treatment (CAT) for children with acute uncomplicated appendicitis (AUA) remains unresolved, with concerns regarding the practicality of CAT. We analyzed our center's experience with CAT for AUA, using a protocol with strict inclusion, exclusion and treatment criteria. METHODS: Non-randomized, prospective cohort study included all children admitted betwee 2014 and 2016, with clinical and laboratory tests suspicious for AUA...
March 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29260130/comparison-of-open-appendectomy-and-laparoscopic-appendectomy-with-laparoscopic-intracorporeal-knotting-and-glove-endobag-techniques-a-prospective-observational-study
#13
Mehmet Aziret, Süleyman Çetinkünar, Hasan Erdem, Şahin Kahramanca, Hilmi Bozkurt, Onur Dülgeroğlu, Ali Cihat Yıldırım, Oktay İrkörücü, Emre Birzad Gölboyu
Objective: Despite the recent increase in the use of laparoscopic appendectomy procedures to treat acute appendicitis, laparoscopic appendectomy is not necessarily the best treatment modality. The aim of this study is to examine the value of laparoscopic intracorporeal knotting and glove endobag in terms of various parameters and in terms of reducing the costs related to laparoscopic appendectomy procedures. Material and Methods: Seventy-two acute appendicitis patients who underwent laparoscopic appendectomy and open appendectomy surgery were enrolled in the study and were evaluated prospectively...
2017: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29217323/noninvasive-monitoring-of-physiologic-compromise-in-acute-appendicitis-new-insight-into-an-old-disease
#14
Young Mee Choi, David Leopold, Kristen Campbell, Jane Mulligan, Greg Z Grudic, Steven L Moulton
INTRODUCTION: Physiologic compromise in children with acute appendicitis has heretofore been difficult to measure. We hypothesized that the Compensatory Reserve Index (CRI), a novel adjunctive cardiovascular status indicator, would be low for children presenting with acute appendicitis in proportion to their physiological compromise, and that CRI would rise with fluid resuscitation and surgical management of their disease. METHODS: Ninety-four children diagnosed with acute appendicitis were monitored with a CipherOx CRI™ M1 pulse oximeter (Flashback Technologies Inc...
February 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29180169/sarcopenia-in-children-with-perforated-appendicitis
#15
Joseph J López, Jennifer N Cooper, Brett Albert, Brent Adler, Denis King, Peter C Minneci
BACKGROUND: Decreased skeletal muscle mass, or sarcopenia, has been shown to be associated with worse postoperative recovery and a higher risk of complications in adult surgical patients. We hypothesized that pediatric patients with complicated appendicitis may experience sarcopenic changes over the course of their treatment. METHODS: The medical records and computed tomography scans of 36 pediatric complex appendicitis patients who had both preoperative and postoperative computerized tomography scans at our hospital were reviewed...
December 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29032983/early-versus-late-surgical-management-of-complicated-appendicitis-in-children-a-statewide-database-analysis-with-one-year-follow-up
#16
Saurabh Saluja, Tianyi Sun, Jialin Mao, Shaun A Steigman, P Stephen Oh, Heather L Yeo, Art Sedrakyan, Demetri J Merianos
BACKGROUND: Complicated appendicitis is common in children, yet the timing of surgical management remains controversial. Some support initial antibiotics with delayed operation whereas others support immediate operation. While a few randomized trials have evaluated this question, they have been small, single-center trials with limited follow-up. We present a database analysis of outcomes in early versus late surgical management of complicated appendicitis with one-year follow-up. METHODS: We conducted a retrospective review of children with complicated appendicitis presenting between 2000 and 2013, utilizing a New York State database...
October 2, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29019885/two-incision-laparoscopic-appendectomy-for-a-severe-hemophilia-a-child-patient-with-coagulation-factor-vii-deficiency-case-report-and-review-of-literature
#17
Jin Peng He, Jie Xiong Feng
RATIONALE: The main complication of patients with severe hemophilia is recurrent bleeding events that usually affected musculoskeletal contractures. And replacement therapy methods were continuously improved to minimize adverse impacts brought by those complications. However, only several cases reported about the appendectomy for hemophilia A. We report a case of acute appendicitis treated by two-incision laparoscopy in a boy with hemophilia A and coagulation factor VII deficiency for the first time...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29016242/early-predictors-of-abscess-development-after-perforated-pediatric-appendicitis
#18
Catherine M Dickinson, Nathan A Coppersmith, Francois I Luks
BACKGROUND: Approximately one-third of children with appendicitis present with advanced disease or perforation. Whereas this increases the risk for post-operative complications and re-admission, it is not yet possible to predict early on who will develop an abdominal abscess. We sought to identify specific risk factors for this complication, in an attempt to streamline post-operative care. PATIENTS AND METHODS: We reviewed the records of all cases of perforated appendicitis over a 12-month period at a tertiary children's hospital...
November 2017: Surgical Infections
https://www.readbyqxmd.com/read/28941724/operative-versus-non-operative-management-in-the-care-of-patients-with-complicated-appendicitis
#19
COMPARATIVE STUDY
Thomas S Helling, Douglas F Soltys, Samantha Seals
BACKGROUND: The approach to complicated appendicitis is unclear. We have sought to determine factors which may persuade surgeons to non-operative management and whether such treatment affects outcome. METHODS: All adult patients admitted over a five-year period 2009-2014 with a diagnosis of appendicitis were reviewed. Patients were grouped into uncomplicated and complicated presentations and stratified by age, gender, ethnicity, socio-economic status, and time to presentation...
December 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28940383/immunoproteasome-in-the-blood-plasma-of-children-with-acute-appendicitis-and-its-correlation-with-proteasome-and-uchl1-measured-by-spr-imaging-biosensors
#20
E Matuszczak, A Sankiewicz, W Debek, E Gorodkiewicz, R Milewski, A Hermanowicz
The aim of this study was to determinate the immunoproteasome concentration in the blood plasma of children with appendicitis, and its correlation with circulating proteasome and ubiquitin carboxyl-terminal hydrolase L1 (UCHL1). Twenty-seven children with acute appendicitis, managed at the Paediatric Surgery Department, were included randomly into the study (age 2 years 9 months up to 14 years, mean age 9·5 ± 1 years). There were 10 girls and 17 boys; 18 healthy, age-matched subjects, admitted for planned surgeries served as controls...
January 2018: Clinical and Experimental Immunology
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