keyword
https://read.qxmd.com/read/38316538/external-validation-of-a-rapid-algorithm-using-high-sensitivity-troponin-assay-results-for-evaluating-patients-with-suspected-acute-myocardial-infarction
#21
JOURNAL ARTICLE
Louise Cullen, Jaimi H Greenslade, Laura Stephensen, Isuru Ranasinghe, Niranjan Gaikwad, Maryam Khorramshahi Bayat, Ehsan Mahmoodi, Martin Than, Fred Apple, William Parsonage
OBJECTIVE: We sought to validate the clinical performance of a rapid assessment pathway incorporating the Siemens Atellica IM high sensitivity cardiac troponin I (hs-cTnI) assay in patients presenting to the emergency department (ED) with suspected acute myocardial infarction (AMI). METHODS: This was a multicentre prospective observational study of adult ED patients presenting to five Australian hospitals between November 2020 and September 2021. Participants included those with symptoms of suspected AMI (without ST-segment elevation MI on presentation ECG)...
February 5, 2024: Emergency Medicine Journal: EMJ
https://read.qxmd.com/read/38309545/a-simple-and-easy-technique-to-overcome-anatomic-challenges-of-transradial-access-in-stemi-patients
#22
REVIEW
Isabel Durães Campos, Carlos Galvão Braga, João Costa, Catarina Quina Rodrigues, Catarina Vieira, Jorge Marques
BACKGROUND: Transradial access (TRA) is associated with fewer access-related complications, earlier discharge and lower mortality than transfemoral access (TFA), being the preferred route to perform primary percutaneous coronary interventions (PPCIs) in STEMI patients. However, the radial artery is smaller, more superficial and thinner than the femoral artery, which may make PPCIs difficult. PURPOSE: This study describes a practical solution to overcome several of the anatomical difficulties during the TRA, demonstrating its outcomes during clinical practice...
February 1, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38304131/clinical-outcome-after-everolimus-eluting-stent-implantation-for-small-vessel-coronary-artery-disease-xience-asia-small-vessel-study
#23
JOURNAL ARTICLE
Doo Sun Sim, Dae Young Hyun, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Sang Rok Lee, Jei Keon Chae, Keun Ho Park, Young Youp Koh, Kyeong Ho Yun, Seok Kyu Oh, Seung Jae Joo, Sun Ho Hwang, Jong Pil Park, Jay Young Rhew, Su Hyun Kim, Jang Hyun Cho, Seung Uk Lee, Dong Goo Kang
There are limited data on outcomes after implantation of everolimus-eluting stents (EES) in East Asian patients with small vessel coronary lesions. A total of 1,600 patients treated with XIENCE EES (Abbott Vascular, CA, USA) were divided into the small vessel group treated with one ≤2.5 mm stent (n=119) and the non-small vessel group treated with one ≥2.75 mm stent (n=933). The primary end point was a patient-oriented composite outcome (POCO), a composite of all-cause death, myocardial infarction (MI), and any repeat revascularization at 12 months...
January 2024: Chonnam Medical Journal
https://read.qxmd.com/read/38302954/wellens-syndrome-prevalence-risk-factors-and-coronary-angiographic-variation-a-cross-sectional-study
#24
JOURNAL ARTICLE
Sami Mohamed, Samoal Abdelaziz
BACKGROUND: Wellens syndrome complicates acute coronary syndrome and, if unmanaged, can lead to immanent myocardial infarction. This study aimed towards determining the prevalence of Wellens syndrome among acute coronary syndrome patients while focusing on both types and identifying the associated risk factors, then exploring the variation in affected coronary arteries within patients fulfilling Wellens syndrome criteria. METHODS: Implementing a descriptive cross sectional hospital based observational study design, at Ahmed Gasim Teaching Hospital for Cardiac Surgery and Renal Transplantation in Khartoum North, Sudan, the study was conducted following using a non probability convenience sampling of patients fitting the inclusion criteria...
February 1, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38298759/management-and-outcomes-of-spontaneous-coronary-artery-dissection-a-systematic-review-of-the-literature
#25
REVIEW
Milovan Petrović, Tatjana Miljković, Aleksandra Ilić, Mila Kovačević, Milenko Čanković, Dragana Dabović, Anastazija Stojšić Milosavljević, Snežana Čemerlić Maksimović, Milana Jaraković, Dragica Andrić, Miodrag Golubović, Marija Bjelobrk, Snežana Bjelić, Snežana Tadić, Jelena Slankamenac, Svetlana Apostolović, Vladimir Djurović, Aleksandra Milovančev
BACKGROUND: Contemporary management of spontaneous coronary artery dissection (SCAD) is still controversial. This systematic review of the literature aims to explore outcomes in the patients treated with conservative management vs. invasive strategy. METHODS: The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed when we extensively searched three electronic databases: PubMed, ScienceDirect, and Web of Science, for studies that compared conservative vs...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38287944/the-effect-of-platelet-activity-abcb1-genetic-polymorphism-and-renal-function-on-the-development-of-ticagrelor-related-dyspnea-in-patients-with-acute-coronary-syndrome
#26
JOURNAL ARTICLE
Vytenis Tamakauskas, Remigijus Žaliūnas, Vaiva Lesauskaitė, Nora Kupstytė-Krištaponė, Ieva Čiapienė, Gintarė Šakalytė, Jurgita Plisienė, Vilius Skipskis, Vacis Tatarūnas
PURPOSE: The aim of this study was to determine the effect of ABCB1 genetic polymorphism and renal function on the occurrence of ticagrelor-related dyspnea. PATIENTS AND METHODS: A total of 299 patients with acute with type 1, 2, or 3 myocardial infarction (with and without ST-segment elevation), who underwent coronary angiography and PTCA with stent implantation and were treated with antiplatelet drugs (ticagrelor and aspirin), were enrolled in this prospective study...
2024: Drug Design, Development and Therapy
https://read.qxmd.com/read/38285607/aspirin-free-strategy-for-percutaneous-coronary-intervention-in-acute-coronary-syndrome-based-on-the-subtypes-of-acute-coronary-syndrome-and-high-bleeding-risk-the-stopdapt-3-trial
#27
JOURNAL ARTICLE
Yuki Obayashi, Masahiro Natsuaki, Hirotoshi Watanabe, Takeshi Morimoto, Ko Yamamoto, Ryusuke Nishikawa, Kenji Ando, Satoru Suwa, Tsuyoshi Isawa, Hiroyuki Takenaka, Tetsuya Ishikawa, Hideo Tokuyama, Hiroki Sakamoto, Takanari Fujita, Mamoru Nanasato, Hideki Okayama, Tenjin Nishikura, Hidekuni Kirigaya, Koji Nishida, Koh Ono, Takeshi Kimura
BACKGROUND AND AIMS: High bleeding risk (HBR) and acute coronary syndrome (ACS) subtypes are critical in determining bleeding and cardiovascular event risk after percutaneous coronary intervention (PCI). METHODS: In 4476 ACS patients enrolled in the STOPDAPT-3, where the no-aspirin and dual antiplatelet therapy (DAPT) strategies after PCI were randomly compared, the pre-specified subgroup analyses were conducted based on HBR/non-HBR and ST-segment elevation myocardial infarction (STEMI)/non-ST-segment elevation ACS (NSTE-ACS)...
January 29, 2024: European Heart Journal. Cardiovascular Pharmacotherapy
https://read.qxmd.com/read/38271596/effects-of-albiglutide-on-myocardial-infarction-and-ischemic-heart-disease-outcomes-in-patients-with-type-2-diabetes-and-cardiovascular-disease-in-the-harmony-outcomes-trial
#28
JOURNAL ARTICLE
Konstantin A Krychtiuk, Guillaume Marquis-Gravel, Shannon Murphy, Karen P Alexander, Karen Chiswell, Jennifer B Green, Lawrence A Leiter, Renato Lopes, Stefano Del Prato, William Schuyler Jones, John J V McMurray, Adrian F Hernandez, Christopher B Granger
AIMS: Large outcome trials have demonstrated cardiovascular benefits of selected glucagon-like peptide-1 (GLP-1) receptor agonists. We examined coronary disease outcomes in the Harmony Outcomes trial of the GLP-1 receptor agonist albiglutide. METHODS AND RESULTS: Harmony Outcomes was an event-driven, multicenter, double-blind, placebo-controlled trial involving 9 463 patients > 40years of age with type-2 diabetes and established atherosclerotic cardiovascular disease...
January 25, 2024: European Heart Journal. Cardiovascular Pharmacotherapy
https://read.qxmd.com/read/38251048/a-refractory-electrical-storm-after-acute-myocardial-infarction-the-role-of-temporary-ventricular-overdrive-pacing-as-a-bridge-to-icd-implantation
#29
Mijo Meter, Josip Andelo Borovac
An electrical storm (ES) is defined as the presence of at least three episodes of sustained ventricular tachycardia or ventricular fibrillation within 24 h. This patient had a previously known arterial hypertension, type II diabetes mellitus, and chronic kidney disease and has presented to the Emergency Department (ED) with symptoms of retrosternal chest pain lasting for several hours prior. The initial 12-lead electrocardiogram revealed ST segment elevation in the anterior leads (V1-V6). Emergent coronary angiography revealed an acute occlusion of the proximal left anterior descending artery (pLAD) and percutaneous coronary intervention was performed with successful implantation of one drug-eluting stent in the pLAD...
January 14, 2024: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://read.qxmd.com/read/38250610/-transcription-factor-21-rs12190287-polymorphism-is-related-to-stable-angina-and-st-elevation-myocardial-infarction-in-a-chinese-population
#30
JOURNAL ARTICLE
Teng-Hung Yu, Thung-Lip Lee, I-Ting Tsai, Chin-Feng Hsuan, Chao-Ping Wang, Yung-Chuan Lu, Wei-Hua Tang, Ching-Ting Wei, Fu-Mei Chung, Yau-Jiunn Lee, Cheng-Ching Wu
Background: Transcription factor 21 (TCF21, epicardin, capsuling, pod-1) is expressed in the epicardium and is involved in the regulation of cell fate and differentiation via epithelial-mesenchymal transformation during development of the heart. In addition, TCF21 can suppress the differentiation of epicardial cells into vascular smooth muscle cells and promote cardiac fibroblast development. This study aimed to explore whether TCF21 gene (12190287G/C) variants affect coronary artery disease risk. Methods: We enrolled 381 patients who had stable angina, 138 with ST elevation myocardial infarction (STEMI), and 276 healthy subjects...
2024: International Journal of Medical Sciences
https://read.qxmd.com/read/38242505/predictors-of-prolonged-hospital-stay-and-in-hospital-mortality-in-female-patients-with-acute-myocardial-infarction-with-specific-reference-to-diabetes
#31
JOURNAL ARTICLE
Ghada Shalaby, Sameh Sabri, Asma Nabat Safar Alsilami, Reem Yousef Alhassani, Suha Hashem Alsayed, Mohannd Amin Wasel Alhazmi, Mohamed Thabet Aoudallah, Sheeren Khaled
This study aimed to determine predictors of prolonged length of stay (LOS) and mortality in female STEMI patients with diabetes in comparison to female STEMI patients without diabetes. This retrospective single-center study was conducted between 2015 and 2020 as part of the STEMI registry in our center and included all STEMI patients. RESULTS: Out of 3081 STEMI patients, 16% (N = 498) were female, and 64% (n = 318) of them had diabetes. Diabetic patients were less commonly presented with anterior wall myocardial infarction (AWMI) (47% vs 65%, p = 0...
January 17, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38233813/spontaneous-coronary-artery-dissection-in-a-young-patient-with-antiphospholipid-syndrome
#32
JOURNAL ARTICLE
Ai Phi Thuy Ho, Eirik Tjønnfjord, Oliver Meyerdierks, Ellen Elisabeth Brodin
A 28-year-old man diagnosed with triple positive antiphospholipid syndrome (APS) and undergoing warfarin experienced three separate admissions to the cardiac ward within a one-month period due to escalating chest pain. While the initial two admissions revealed normal results in cardiological investigations, such as blood tests, electrocardiogram, and echocardiography, the third admission unveiled signs of ST-elevation myocardial infarction (STEMI), despite the patient maintaining an INR (International Normalized Ratio) of 4...
January 17, 2024: Thrombosis Journal
https://read.qxmd.com/read/38224955/improved-heart-function-and-cardiac-remodelling-following-sacubitril-valsartan-in-acute-coronary-syndrome-with-hf
#33
JOURNAL ARTICLE
Henan Liu, Yongkang Su, Jian Shen, Yang Jiao, Ying Li, Bing Liu, Xiaoling Hou, Qinhua Jin, Yundai Chen, Zhijun Sun, Qing Xi, Bin Feng, Zhenhong Fu
AIMS: This study sought to assess the effect of treatment of sacubitril/valsartan (S/V) on improving cardiac function and reversing cardiac remodelling in patients with acute coronary syndrome (ACS) complicated with heart failure with reduced ejection fraction after percutaneous coronary intervention (PCI). METHODS AND RESULTS: We enrolled 275 ACS patients with reduced left ventricular ejection fraction after PCI. The patients were divided into the routine and S/V groups according to the treatment drugs...
January 15, 2024: ESC Heart Failure
https://read.qxmd.com/read/38196467/angiographic-characteristics-of-culprit-lesions-in-infarct-related-artery-and-correlation-of-timi-score-with-syntax-score-to-predict-extent-and-severity-of-coronary-artery-disease-in-patients-undergoing-primary-percutaneous-coronary-interventions
#34
JOURNAL ARTICLE
Rizwanullah, Jawaid Akbar Sial, Nasir Ali, M Shehzad
OBJECTIVE: The current study was designed to explore the relationship of TIMI and SYNTAX risk score to predict the CAD extent and severity in STEMI patients. METHODS: For this cross-sectional study, 304 STEMI patients undergoing PPCI were enrolled at Department of Interventional Cardiology NICVD Karachi from September 2021 to January 2022. and the TIMI risk score was determined at enrolment. Based on these scorings, the patients were grouped as low, intermediate, and high risk, i...
2024: Pakistan Journal of Medical Sciences Quarterly
https://read.qxmd.com/read/38194245/sex-age-interplay-among-young-aged-egyptians-with-first-acute-myocardial-infarction
#35
JOURNAL ARTICLE
Ibtesam I El-Dosouky, Montaser M El Seqelly, Ahmed M Ebrahiem, Mohamed Abdelhady Mohamed
BACKGROUND: The burden of modifiable risk factors in young Egyptian adults presenting with first acute myocardial infarction (AMI), sex differences, sex-age interplay and its relationship with demographic, angiographic characteristics and type of AMI is a good topic for discussion. METHODS: The study enrolled 165 young (≤45 years old) consecutive, eligible patients diagnosed with first AMI (ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), for their demographic, angiographic, echocardiographic and laboratory investigations and gender differences...
December 29, 2023: Critical Pathways in Cardiology
https://read.qxmd.com/read/38185283/pseudo-targeted-metabolic-profile-differences-between-emergency-patients-with-type-1-and-type-2-myocardial-infarction-diagnosed-by-optical-coherence-tomography
#36
JOURNAL ARTICLE
Jifei Wang, Zhaoying Li, Guang Yang, Chao Fang, Yanwei Yin, Zhilei Zheng, Hongwei Wang, Shaohong Fang, Jiannan Dai, Shanjie Wang, Shuang Yang, Bo Yu
BACKGROUND: It is difficult to distinguish type 2 myocardial infarction (T2MI) from type 1 myocardial infarction (T1MI), although their management varies. OBJECTIVES: Using optical coherence tomography (OCT) and pseudo-targeted metabolomics to identify biomarkers, investigate metabolic differences, and establish a T2MI subclassification. METHODS: Among 1519 patients with MI, 97 T2MI patients are identified who are 1:1 matched with 97 T1MI patients after considering age, gender, ST-segment elevation, time from onset to coronary angiography, and hs-cTnI on admission by propensity score matching...
January 5, 2024: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://read.qxmd.com/read/38173784/the-first-reported-case-of-intravascular-ultrasound-guided-reverse-overlapping-stenting-of-a-long-calcified-lesion-using-ultra-low-contrast-and-metallic-roadmaps-case-report
#37
Massoud A Leesar, Shao-Liang Chen
BACKGROUND: Percutaneous coronary intervention (PCI) of a long calcified coronary lesion in patients with chronic kidney disease (CKD) is challenging and can lead to stent under-expansion and contrast-induced acute kidney injury (CI-AKI). We described the first case of intravascular ultrasound (IVUS)-guided reverse overlapping stenting of long calcified left anterior descending (LAD) coronary lesion using ultra-low contrast and the metallic roadmaps to prevent CI-AKI after PCI. CASE SUMMARY: A 77-year-old man with a history of hypertension, type 2 diabetes, and CKD was admitted with angina class 4 and ruled in for non-ST-elevation myocardial infarction...
January 2024: European Heart Journal. Case Reports
https://read.qxmd.com/read/38162099/clinical-significance-of-carotid-intima-media-thickness-and-plasma-homocysteine-in-acute-st-segment-elevation-myocardial-infarction
#38
JOURNAL ARTICLE
Qiaoyun Ou, Jing Zhang, Xiang Wen, Linfei Yang, Lihua Tao
BACKGROUND: Patients with acute ST-segment elevation myocardial infarction (STEMI) often have fewer identifiable traditional risk factors compared to other types of acute coronary syndrome. Therefore, it is necessary to explore more sensitive predictive models different from traditional cardiovascular scoring systems to identify high-risk populations. The retrospective case-control study aimed to investigate the predictive value of carotid intima-media thickness (CIMT) and homocysteine (Hcy) on the occurrence of STEMI...
December 15, 2023: Cardiovascular Diagnosis and Therapy
https://read.qxmd.com/read/38149142/misleading-presentation-chest-pain-masking-euglycemic-diabetic-ketoacidosis-possibly-induced-by-empagliflozin
#39
Kripa Tiwari, Nava R Sharma, Madalasa Pokhrel, Arjun Basnet, Michael Kaplan
Diabetic ketoacidosis (DKA) is a life-threatening metabolic emergency traditionally associated with Type 1 diabetes but is increasingly recognized in Type 2 diabetes, particularly with the use of sodium-glucose cotransporter-2 (SGLT-2) inhibitors. Euglycemic DKA, characterized by near-normal blood glucose levels, is a distinct variant that has gained attention. This case report highlights a unique presentation of euglycemic DKA in a 56-year-old female with a past medical history of Type 2 Diabetes Mellitus who presented to the emergency department with a one-week history of chest pain...
November 2023: Curēus
https://read.qxmd.com/read/38110389/comparing-the-long-term-outcomes-in-chronic-coronary-syndrome-patients-with-prior-st-segment-and-non-st-segment-elevation-myocardial-infarction-findings-from-the-tigris-registry
#40
JOURNAL ARTICLE
Sibi N Krishnamurthy, Stuart Pocock, Prashant Kaul, Ruth Owen, Shaun G Goodman, Christopher B Granger, Jose Carlos Nicolau, Tabassome Simon, Dirk Westermann, Satoshi Yasuda, Karolina Andersson, Gunnar Brandrup-Wognsen, Phillip R Hunt, David B Brieger, Mauricio G Cohen
OBJECTIVES: Compared with ST-segment elevation myocardial infarction (STEMI) patients, non-STEMI (NSTEMI) patients have more comorbidities and extensive coronary artery disease. Contemporary comparative data on the long-term prognosis of stable post-myocardial infarction subtypes are needed. DESIGN: Long-Term rIsk, clinical manaGement and healthcare Resource utilisation of stable coronary artery dISease (TIGRIS) was a multinational, observational and longitudinal cohort study...
December 18, 2023: BMJ Open
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