keyword
https://read.qxmd.com/read/38492976/clinical-outcomes-with-biodegradable-versus-durable-polymer-drug-eluting-stents-in-patients-with-st-elevation-myocardial-infarction
#1
JOURNAL ARTICLE
Gustavo Neves de Araujo, Guilherme Pinheiro Machado, Marcia Moura, Anderson Donelli Silveira, Luiz Carlos Bergoli, Felipe Costa Fuchs, Rodrigo Vugman Wainstein, Sandro Cadaval Goncalves, Pedro A Lemos, Alexandre Schaan de Quadros, Marco Vugman Wainstein
BACKGROUND: Coronary drug-eluting stents (DES) built with either durable (DP) or biodegradable (BP) polymeric coatings have been largely tested and are extensively available for routine use. However, their comparative performance remains an open question, particularly in more complex subsets of patients. AIMS: We evaluated the outcomes of patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI) using DP-DES versus BP-DES in a large multicenter real-world registry...
March 8, 2024: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/38487067/antithrombotic-management-and-outcomes-of-anterior-st-elevation-myocardial-infarction-with-new-onset-wall-motion-abnormalities-in-men-and-women
#2
JOURNAL ARTICLE
Laurie-Anne Boivin-Proulx, Fabrice Ieroncig, Simon-Pierre Demers, Anna Nozza, Marwa Soltani, Ismahane Ghersi, Louis Verreault-Julien, Yahya Alansari, Charles Massie, Philippe Simard, Lorena Rosca, Jean-Simon Lalancette, Gabriel Massicotte, Annabel Chen-Tournoux, Benoit Daneault, Jean-Michel Paradis, Jean G Diodati, Nicolas Pranno, Marc Jolicoeur, Brian J Potter, Guillaume Marquis-Gravel, Christine Pacheco
BACKGROUND: In patients with anterior ST-elevation myocardial infarction (STEMI) and new-onset antero-apical wall motion abnormalities (WMAs), whether the rate of prophylaxis against left ventricular thrombus and outcomes differ between men and women is unknown. METHODS: A multicentre retrospective cohort study of patients with STEMI and new-onset antero-apical WMAs treated with primary percutaneous coronary intervention was conducted. Patients with an established indication of oral anticoagulation (OAC) were excluded...
February 2024: CJC open
https://read.qxmd.com/read/38481088/treatment-and-outcomes-of-patients-with-chronic-lung-disease-and-acute-myocardial-infarction-insights-from-the-nationwide-amis-plus-registry
#3
JOURNAL ARTICLE
C Beckmann, F Foster-Witassek, M Brutsche, M T Maeder, F Eberli, M Roffi, G Pedrazzini, D Radovanovic, H Rickli
BACKGROUND: Limited data are available on patients with chronic lung disease (CLD) presenting with acute myocardial infarction (AMI). We aimed to analyse baseline characteristics, treatment and outcome of those patients enrolled in the Swiss nationwide prospective AMIS Plus registry. METHODS: All AMI patients enrolled between January 2002 and December 2021 with data on CLD, as defined in the Charlson Comorbidity Index, were included. The primary endpoints were in-hospital mortality and major adverse cardiac and cerebrovascular events (MACCE), defined as all-cause death, reinfarction and cerebrovascular events...
March 13, 2024: European Journal of Clinical Investigation
https://read.qxmd.com/read/38467788/the-new-esc-acute-coronary-syndrome-guideline-and-its-impact-in-the-cpu-and-emergency-department-setting
#4
REVIEW
Martin Möckel
The new guideline on acute coronary syndrome (ACS) of the European Society of Cardiology (ESC) replaces two separate guidelines on ST-elevation myocardial infarction (STEMI) and non-ST-elevation (NSTE) ACS. This change of paradigm reflects the experts view that the ACS is a continuum, starting with unstable angina and ending in cardiogenic shock or cardiac arrest due to severe myocardial ischemia. Secondary, partly non-atherosclerotic-caused myocardial infarctions ("type 2") are not integrated in this concept...
March 11, 2024: Herz
https://read.qxmd.com/read/38465191/analysis-of-the-weekend-effect-on-mortality-diagnostic-coronary-angiography-and-percutaneous-coronary-intervention-in-acute-myocardial-infarction-across-rural-us-hospitals
#5
JOURNAL ARTICLE
Mirza Faris Ali Baig
BACKGROUND: Rural hospitals face several unique challenges in delivering healthcare to an underserved population. Achieving time-sensitive goals in a resource-scarce facility is often a difficult task without the right team at hand. Resources are further depleted on the weekends, exposing understaffed hospitals to poorer outcomes. Acute myocardial infarction (AMI) mortality depends on timely diagnosis and intervention. It is unknown to what extent resource shortages impact rural hospitals during weekends and how they affect AMI mortality...
February 2024: Curēus
https://read.qxmd.com/read/38465089/type-2-myocardial-infarction-caused-by-orthostatic-hypotension-with-post-transcatheter-aortic-valve-implantation-a-case-report
#6
Hitomi Tsuchida, Shiho Amano, Chiaki Sano, Ryuichi Ohta
This case report delineates the occurrence and management of type 2 myocardial infarction (MI) in an 89-year-old woman following transcatheter aortic valve implantation (TAVI). The patient, with a history of severe aortic stenosis, hypertension, dyslipidemia, and colorectal cancer, presented with nausea and significant hypotension. Initial assessments revealed elevated troponin levels, atrial fibrillation, and ST-segment depression, leading to a diagnosis of type 2 MI. This condition was attributed to the interplay between left ventricular hypertrophy, hypotension-induced dehydration, and increased myocardial oxygen demand...
February 2024: Curēus
https://read.qxmd.com/read/38425811/a-curious-case-of-type-iv-dual-lad-presenting-with-st-elevation-myocardial-infarction
#7
Sushant Kharel, Kunjang Sherpa, Sanjay Singh Kc, Dipanker Prajapati, Rikesh Tamrakar
No abstract text is available yet for this article.
February 2024: AsiaIntervention
https://read.qxmd.com/read/38418004/angiotensin-receptor-neprilysin-inhibition-in-patients-with-stemi%C3%A2-vs%C3%A2-nstemi
#8
RANDOMIZED CONTROLLED TRIAL
Douglas L Mann, Johny Nicolas, Brian Claggett, Zi Michael Miao, Christopher B Granger, Prafulla Kerkar, Lars Køber, Eldrin F Lewis, John J V McMurray, Aldo P Maggioni, Julio Núñez, Mpiko Ntsekhe, Jean-Lucien Rouleau, David Sim, Scott D Solomon, Philippe Gabriel Steg, Peter van der Meer, Eugene Braunwald, Marc A Pfeffer, Roxana Mehran
BACKGROUND: Patients who sustain an acute myocardial infarction (AMI), including ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI), remain at high risk for heart failure (HF), coronary events, and death. Angiotensin-converting enzyme inhibitors have been shown to significantly decrease the risk for cardiovascular events in both STEMI and NSTEMI patients. OBJECTIVES: The objectives were to determine whether angiotensin-receptor blockade and neprilysin inhibition with sacubitril/valsartan, compared with ramipril, has impact on reducing cardiovascular events according to the type of AMI...
March 5, 2024: Journal of the American College of Cardiology
https://read.qxmd.com/read/38402926/long-term-outcomes-of-pharmacoinvasive-strategy-vs-primary-percutaneous-coronary-intervention-in-st-elevation-myocardial-infarction-a-study-from-mexico-city
#9
JOURNAL ARTICLE
Alexandra Arias-Mendoza, Rodrigo Gopar-Nieto, Jessica Juarez-Tolen, Juan Carlos Ordóñez-Olvera, Héctor Gonzalez-Pacheco, Jose Luis Briseño-De la Cruz, Daniel Sierra-Lara Martinez, Salvador Mendoza-García, Alfredo Altamirano-Castillo, Alvaro Montañez-Orozco, Arturo Arzate Ramirez, Luis A Baeza-Herrera, Jorge A Ortega-Hernandez, Greta Miranda-Cerda, Jesus Erick Cruz-Martinez, Francisco Martin Baranda-Tovar, Carlos Zabal-Cerdeira, Diego Araiza-Garaygordobil
While primary percutaneous coronary intervention (pPCI) is the treatment of choice in ST elevation myocardial infarction (STEMI), challenges may arise in accessing this intervention for certain geodemographic groups. Pharmacoinvasive strategy (PIs) has demonstrated comparable outcomes when delays in pPCI are anticipated, but real-world data on long-term outcomes are limited. The aim of the present study was to compare long-term outcomes among real world patients with STEMI undergoing either PIs or pPCI. This was a prospective registry including patients with STEMI who received reperfusion during the first 12 hours from symptom onset...
February 23, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38401651/association-of-myocardial-injury-and-outcomes-in-patients-hospitalized-with-covid-19
#10
JOURNAL ARTICLE
Satyam Krishan, Khawaja Hassan Akhtar, Siddharth Agarwal, Jehanzeb Khan, Usman Baber
No abstract text is available yet for this article.
February 22, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38380174/case-report-kounis-syndrome-due-to-cryptopteran-bite
#11
Rui Liao, Shengjie Cheng, Nan Xu
BACKGROUND: Kounis syndrome is an acute coronary syndrome (ACS) caused by allergic reactions, including coronary artery spasm (type I) caused by allergies without coronary predisposing factors, pre-existing coronary atherosclerosis, and coronary artery disease. Anaphylaxis leads to plaque rupture or erosion leading to acute myocardial infarction (type II) and acute coronary stent thrombosis (type III). Here we share a case of Kounis syndrome type I caused by an allergy caused by a Cryptopteran bite...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38369132/copeptin-for-the-differentiation-of-type-1-versus-type-2-myocardial-infarction-or-myocardial-injury
#12
JOURNAL ARTICLE
Mona Kassem, Pedro Lopez Ayala, Tijana Andric-Cancarevic, Milos Tajsic, Kris G Vargas, Dimitri Bendik, Christoph Kaufmann, Johann Wojta, Christian Mueller, Kurt Huber
BACKGROUND: The rapid and reliable differentiation of myocardial infarction (MI) due to atherothrombosis (T1MI) from MI due to supply-demand mismatch (T2MI) or acute myocardial injury is of major clinical relevance due to very different treatments, but still a major unmet clinical need. This study aimed to investigate whether copeptin, a stress hormone produced in the hypothalamus, helps to differentiate between T1MI versus T2MI or injury. METHODS: In a retrospective analysis, 1271 unselected consecutive patients presenting with symptoms suggestive of MI to the emergency department were evaluated...
February 16, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38360558/diagnostic-challenges-between-takotsubo-cardiomyopathy-and-acute-myocardial-infarction-where-is-the-emergency-a-literature-review
#13
REVIEW
Alexandru Scafa-Udriste, Ruxandra-Nicoleta Horodinschi, Miruna Babos, Bogdan Dinu
BACKGROUND: Takotsubo cardiomyopathy (TC) is an emergency cardiovascular disease, with clinical and paraclinical manifestations similar to acute myocardial infarction (AMI), but it is characterized by reversible systolic dysfunction of the left ventricle (LV) in the absence (most of the time) of obstructive coronary artery disease (CAD). MANAGEMENT OF PATIENTS WITH TC: TC seems to be more frequent in post-menopausal women and it is triggered by emotional or physical stress...
February 15, 2024: International Journal of Emergency Medicine
https://read.qxmd.com/read/38352639/successful-primary-pci-in-stanford-type-a-aortic-dissection-complicated-by-inferior-st-elevation-myocardial-infarction-a-case-in-a-facility-with-no-surgical-backup
#14
Suko Adiarto, Novi Kurnianingsih, Indra Prasetya, Faris W Nugroho, Raman Uberoi
Mortality of type A aortic dissection (TAAD) complicated with coronary malperfusion syndrome is very high even when emergency surgery is performed. Several reports suggested that primary percutaneous coronary intervention (PPCI) followed by immediate corrective surgery may reduce mortality. In many countries, immediate transfer to an aortic surgery center may not be possible. We report a case of TAAD complicated by coronary malperfusion successfully treated with PPCI followed by elective corrective surgery...
February 2024: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://read.qxmd.com/read/38350507/long-term-pci-outcomes-in-chronic-versus-acute-coronary-syndromes-target-all-comers-trial
#15
JOURNAL ARTICLE
Kush P Patel, Alexandra J Lansky, Henning Kelbæk, Bo Xu, Niels van Royen, Thomas W Johnson, Richard Anderson, William Wijns, Andreas Baumbach
In the TARGET All Comers trial, the biodegradable-polymer sirolimus-eluting FIREHAWK stent (BP SES) was non-inferior to the durable-polymer everolimus-eluting XIENCE stent (DP EES) with respect to target lesion failure (TLF) at 1 and 5 years; however, long-term safety and efficacy in the setting of acute coronary syndromes (ACS) are not known. We sought to assess the long-term outcomes in ACS vs chronic coronary syndromes (CCS) with BP SES vs DP EES. The TARGET AC study was a multicenter, open-label, noninferiority trial of all comer patients randomized 1:1 to BP SES or DP EES (stratified by ST-elevation myocardial infarction and study site)...
February 11, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38348777/association-of-angiotensin-ii-receptor-type%C3%A2-1-and-endothelin-1-receptor-type-a-agonistic-autoantibodies-with-adverse-remodeling-and-cardiovascular-events-after-acute-myocardial-infarction
#16
JOURNAL ARTICLE
Francesco Tona, Giovanni Civieri, Marta Vadori, Giulia Masiero, Laura Iop, Martina Perazzolo Marra, Valentina Perin, Elisa Cuciz, Annagrazia Cecere, Giacomo Bernava, Donatella Tansella, Nataliia Naumova, Simran Grewal, Emanuele Cozzi, Sabino Iliceto
BACKGROUND: The left ventricular remodeling (LVR) process has limited the effectiveness of therapies after myocardial infarction. The relationship between autoantibodies activating AT1R-AAs (angiotensin II receptor type 1-AAs) and ETAR-AAs (autoantibodies activating endothelin-1 receptor type A) with myocardial infarction has been described. Among patients with ST-segment-elevation myocardial infarction, we investigated the relationship between these autoantibodies with LVR and subsequent major adverse cardiac events...
February 13, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38344871/machine-learning-for-myocardial-infarction-compared-with-guideline-recommended-diagnostic-pathways
#17
JOURNAL ARTICLE
Jasper Boeddinghaus, Dimitrios Doudesis, Pedro Lopez-Ayala, Kuan Ken Lee, Luca Koechlin, Karin Wildi, Thomas Nestelberger, Raphael Borer, Òscar Miró, F Javier Martin-Sanchez, Ivo Strebel, Maria Rubini Giménez, Dagmar I Keller, Michael Christ, Anda Bularga, Ziwen Li, Amy V Ferry, Chris Tuck, Atul Anand, Alasdair Gray, Nicholas L Mills, Christian Mueller
BACKGROUND: Collaboration for the Diagnosis and Evaluation of Acute Coronary Syndrome (CoDE-ACS) is a validated clinical decision support tool that uses machine learning with or without serial cardiac troponin measurements at a flexible time point to calculate the probability of myocardial infarction (MI). How CoDE-ACS performs at different time points for serial measurement and compares with guideline-recommended diagnostic pathways that rely on fixed thresholds and time points is uncertain...
February 12, 2024: Circulation
https://read.qxmd.com/read/38341860/temporal-biomarker-concentration-patterns-during-the-early-course-of-acute-coronary-syndrome
#18
JOURNAL ARTICLE
Kai M Eggers, Gorav Batra, Bertil Lindahl, Tatevik Ghukasyan Lakic, Johan Lindbäck, Andrzej Budaj, Jan H Cornel, Evangelos Giannitsis, Hugo A Katus, Robert F Storey, Richard C Becker, Agneta Siegbahn, Lars Wallentin
OBJECTIVES: Biomarker concentrations and their changes during acute coronary syndrome (ACS) provide clinically useful information on pathophysiological processes, e.g. myocardial necrosis, hemodynamic stress and inflammation. However, current evidence on temporal biomarker patterns early during ACS is limited, and studies investigating multiple biomarkers are lacking. METHODS: We measured concentrations of high-sensitivity cardiac troponin T (hs-cTnT) and I (hs-cTnI), NT-terminal pro-B-type natriuretic peptide, C-reactive protein, and growth-differentiation factor-15 (GDF-15) in plasma samples obtained at randomization in ACS patients from the PLATelet inhibition and patient Outcomes (PLATO) trial...
February 13, 2024: Clinical Chemistry and Laboratory Medicine: CCLM
https://read.qxmd.com/read/38333846/efficacy-and-safety-of-drug-coated-balloon-for-de-novo-lesions-of-large-coronary-arteries-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
JOURNAL ARTICLE
Jin-Li Jiang, Qiao-Juan Huang, Meng-Hua Chen
BACKGROUND: Drug-coated balloon (DCB) is a novel approach to avoiding stent-related complications and has proven effective for the treatment of in-stent restenosis (ISR) and small vessels. However, its role in the treatment of de novo lesions in large vessels is less settled. AIMS: To estimate the efficacy and safety of drug-coated balloon versus stent in the treatment of de novo lesions in large coronary arteries. METHODS: We searched the literature until April 2023...
February 15, 2024: Heliyon
https://read.qxmd.com/read/38319434/effects-of-cardiovascular-risk-factors-and-pre-existing-diseases-on-the-short-term-outcome-of-takotsubo-syndrome
#20
JOURNAL ARTICLE
Roya Anahita Mousavi, Andreas Schober, Christina Kronberger, Emilie Han, Brigitte Litschauer, Gernot Pichler, Roza Badr Eslam
BACKGROUND: The effects of cardiovascular risk factors (CVRF) on the development of most acute cardiac conditions are well established; however, little is known about the frequency and effects of CVRF in Takotsubo syndrome (TTS) patients. OBJECTIVE: The aim of our study was to compare the frequency of CVRF and pre-existing diseases (PD) of TTS patients to ST-elevation myocardial infarction (STEMI) patients and analyze their effects on short-term outcome. METHODS: We analyzed the frequency of CVRF (hypertension, hyperlipidemia, type II diabetes mellitus, smoking, chronic kidney disease, family history) as well as somatic and psychiatric PD at admission in TTS patients and compared them with STEMI patients...
February 6, 2024: Wiener Klinische Wochenschrift
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