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https://www.readbyqxmd.com/read/28937904/periodontal-pathogen-colonization-in-young-children-by-pcr-quantification-a-longitudinal-survey
#1
Karine Takahashi, Robson Frederico Cunha, Elerson Gaetti Jardim Junior
INTRODUCTION: Periodontal diseases are among the leading causes of premature tooth loss in adults, but the microbiota associated with this problem is established over time in childhood. AIM: This longitudinal study aimed to verify the occurrence of periodontal pathogens in the oral cavity of children aged six, twelve, eighteen and twenty-four months through PCR quantification, correlating them with the oral microbiota of their mothers. STUDY DESIGN: Saliva and oral biofilm samples were collected from mothers and children by using sterilized paper points...
September 22, 2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28935490/immediate-loading-of-subcrestally-placed-dental-implants-in-anterior-and-premolar-sites
#2
Anders Henningsen, Ralf Smeets, Kai Köppen, Susanne Sehner, Frank Kornmann, Alexander Gröbe, Max Heiland, Till Gerlach
PURPOSE: Immediate loading of dental implants has been evolving into an appropriate procedure for the treatment of partially edentulous jaws. The purpose of this study was to evaluate the clinical success and radiological outcome of immediately and delayed loaded dental implants in anterior and premolar sites. MATERIALS AND METHODS: In this retrospective study, data of 163 individuals requiring tooth removal with subsequent implant placement in anterior and premolar sites were analyzed...
August 23, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28934386/expression-of-the-neuropathy-associated-mtmr2-gene-rescues-mtm1-associated-myopathy
#3
Matthieu A Raess, Belinda S Cowling, Dimitri L Bertazzi, Christine Kretz, Bruno Rinaldi, Jean-Marie Xuereb, Pascal Kessler, Norma B Romero, Bernard Payrastre, Sylvie Friant, Jocelyn Laporte
Myotubularins (MTMs) are active or dead phosphoinositides phosphatases defining a large protein family conserved through evolution and implicated in different neuromuscular diseases. Loss-of-function mutations in MTM1 cause the severe congenital myopathy called myotubular myopathy (or X-linked centronuclear myopathy) while mutations in the MTM1-related protein MTMR2 cause a recessive Charcot-Marie-Tooth peripheral neuropathy. Here we aimed to determine the functional specificity and redundancy of MTM1 and MTMR2, and to assess their abilities to compensate for a potential therapeutic strategy...
October 1, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28932154/malpositioned-canine-treatment-with-autotransplantation-and-laser
#4
Serap Keskin Tunc, Mehmet Savas Kayasan, Esma Ozeroglu, Cennet Neslihan Eroglu
Children and young adults often have tooth loss due to congenital tooth deficiency, trauma, or caries. Autotransplantation has many benefits. The transplanted tooth can be moved orthodontically, maintains alveolar bone growth potential during eruption, and functional periodontal ligament function also permits tooth eruption, allows the defected areas to be filled with the bones; gingival contour is much more successful than the one obtained with prosthesis. In this paper, treatment steps and follow-up results of autotransplantation case supported with biostimulation are mentioned...
July 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28929520/a-short-report-on-tooth-replacement-in-an-older-suburban-population-in-nigeria
#5
Olushola Ibiyemi, Folake B Lawal
OBJECTIVES: To determine: the knowledge of the participants about removable dentures, importance of tooth replacement; prevalence of tooth loss and denture use; and factors associated with its non-use among an elderly population in Nigeria. BACKGROUND: Tooth loss without replacement can impact negatively on the quality of life of the elders, thus making use of denture a basic requirement for those with partial or complete edentulous arches in developed countries...
September 20, 2017: Gerodontology
https://www.readbyqxmd.com/read/28928197/impact-of-oral-self-care-on-incident-functional-disability-in-elderly-japanese-the-ohsaki-cohort-2006-study
#6
Shino Bando, Yasutake Tomata, Jun Aida, Kemmyo Sugiyama, Yumi Sugawara, Ichiro Tsuji
OBJECTIVES: To assess whether oral self-care (tooth brushing, regular dental visits and use of dentures) affects incident functional disability in elderly individuals with tooth loss. DESIGN: A 5.7-year prospective cohort study. SETTING: Ohsaki City, Japan. PARTICIPANTS: 12 370 community-dwelling individuals aged 65 years and older. PRIMARY OUTCOME MEASURES: Incident functional disability (new long-term care insurance certification)...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28924033/rgpf-is-required-for-maintenance-of-stress-tolerance-and-virulence-in-streptococcus-mutans
#7
C J Kovacs, R C Faustoferri, R G Quivey
Bacterial cell wall dynamics have been implicated as important determinants of cellular physiology, stress tolerance and virulence. In Streptococcus mutans, the cell wall is composed primarily of a rhamnose-glucose polysaccharide (RGP) linked to the peptidoglycan. Despite extensive studies describing its formation and composition, the potential roles for RGP in S. mutans biology have not been well investigated. The present study characterizes the impact of RGP disruption as a result of deletion of rgpF, the gene encoding a rhamnosyltransferase involved in construction of the core poly-rhamnose backbone of RGP...
September 18, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28917830/al-awadi-raas-rothschild-syndrome-with-dental-anomalies-and-a-novel-wnt7a-mutation
#8
Piranit Nik Kantaputra, Seema Kapoor, Prashant Verma, Massupa Kaewgahya, Katsushige Kawasaki, Atsushi Ohazama, James R Ketudat Cairns
Al-Awadi-Raas-Rothschild syndrome (AARRS; OMIM 276820) is a very rare autosomal recessive limb malformation syndrome caused by WNT7A mutations. AARRS is characterized by various degrees of limb aplasia and hypoplasia. Normal intelligence and malformations of urogenital system are frequent findings. Complete loss of WNT7A function has been shown to cause AARRS, however, its partial loss leads to the milder malformation, Fuhrmann syndrome. An Indian boy affected with AARRS is reported. A novel homozygous base substitution mutation c...
September 13, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/28914656/charcot-marie-tooth-disease-type-1a-influence-of-body-mass-index-on-nerve-conduction-studies-and-on-the-charcot-marie-tooth-examination-score
#9
Nivedita U Jerath, Michael E Shy
PURPOSE: Charcot-Marie-Tooth Disease type 1A (CMT1A) is caused by a duplication of the peripheral myelin protein gene 22 at chromosome 17p11.2-12. There is limited data regarding whether body mass index (BMI) affects electrophysiological or clinical data in those with CMT1A. METHODS: Electrophysiological data, the Charcot-Marie-Tooth examination score (CMTES) and BMI from 101 patients with known CMT1A were obtained and analyzed. RESULTS: When controlling for age, a higher BMI does not affect ulnar motor nerve conduction studies in those with CMT1A, but rather components of the CMTES (loss of pinprick and motor strength in the lower extremities)...
September 11, 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28914255/microabrasion-remineralization-mab-re-an-innovative-approach-for-dental-fluorosis
#10
Anshula Neeraj Deshpande, Neelam Hasmukhbhi Joshi, Neha Rajesh Pradhan, Rameshwari Yahpal Raol
Enamel microabrasion is a noninvasive method that removes intrinsic and superficial defects from teeth aimed to improve dental esthetic with minimal loss of dental tissue. This case presentation describes the attempt for teeth color correction utilizing that conservative technique in a young girl whose maxillary anterior teeth presented an opaque white/brown stain. Along with microabrasion, an innovative approach of application of casein phosphopeptide-amorphous calcium phosphate crème on the tooth, and remineralization was carried out thereby reducing postoperative sensitivity of the treated tooth...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28912945/comparison-of-er-yag-laser-and-ultrasonic-scaler-in-the-treatment-of-moderate-chronic-periodontitis-a-randomized-clinical-trial
#11
Reza Birang, Jaber Yaghini, Naeimeh Nasri, Nasim Noordeh, Pedram Iranmanesh, Alireza Saeidi, Narges Naghsh
Introduction: Periodontitis is an inflammatory periodontal disease that leads to tooth loss. Recently laser has been introduced as an alternative treatment for periodontitis. The aim of the present study was to compare the effect of Erbium-doped Yttrium Aluminum Garnet (Er:YAG) laser with ultrasonic scaler in patients with moderate chronic periodontitis. Methods: In this randomized single-blind clinical trial, 27 patients with moderate chronic periodontitis were selected. One quadrant of the patients was treated by Er:YAG laser and the other one by ultrasonic scaler...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/28910570/nine-novel-pax9-mutations-and-a-distinct-tooth-agenesis-genotype-phenotype
#12
S-W Wong, D Han, H Zhang, Y Liu, X Zhang, M Z Miao, Y Wang, N Zhao, L Zeng, B Bai, Y-X Wang, H Liu, S A Frazier-Bowers, H Feng
Tooth agenesis is one of the most common developmental anomalies affecting function and esthetics. The paired-domain transcription factor, Pax9, is critical for patterning and morphogenesis of tooth and taste buds. Mutations of PAX9 have been identified in patients with tooth agenesis. Despite significant progress in the genetics of tooth agenesis, many gaps in knowledge exist in refining the genotype-phenotype correlation between PAX9 and tooth agenesis. In the present study, we complete genetic and phenotypic characterization of multiplex Chinese families with nonsyndromic (NS) tooth agenesis...
September 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28906456/effects-of-%C3%AE-glucans-ingestion-on-alveolar-bone-loss-intestinal-morphology-systemic-inflammatory-profile-and-pancreatic-%C3%AE-cell-function-in-rats-with-periodontitis-and-diabetes
#13
Viviam de O Silva, Raquel V Lobato, Eric F Andrade, Débora R Orlando, Bruno D B Borges, Márcio G Zangeronimo, Raimundo V de Sousa, Luciano J Pereira
This study aimed to evaluate the effects of β-glucan ingestion (Saccharomyces cerevisiae) on the plasmatic levels of tumor necrosis factor-α (TNF-α) and interleukin-10 (IL-10), alveolar bone loss, and pancreatic β-cell function (HOMA-BF) in diabetic rats with periodontal disease (PD). Besides, intestinal morphology was determined by the villus/crypt ratio. A total of 48 Wistar rats weighing 203 ± 18 g were used. Diabetes was induced by the intraperitoneal injection of streptozotocin (80 mg/kg) and periodontal inflammation, by ligature...
September 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28905475/evaluation-of-volumetric-dimensional-changes-in-posterior-extraction-sites-with-and-without-arp-using-a-novel-imaging-device
#14
Carolina Sbordone, Paolo Toti, Ranieri Martuscelli, Franco Guidetti, Massimo Porzio, Ludovico Sbordone
BACKGROUND: Alveolar ridge volume loss may be minimized when postextraction sockets are filled by bone substitutes. PURPOSE: The aim of the study was to measure the effect of alveolar ridge preservation (ARP) in maintaining the external contour of the ridge after fresh socket grafting with or without particulate anorganic bovine bone mineral (BBM) and resorbable barrier covering. MATERIALS AND METHODS: In the present controlled study, patients subjected to single-tooth extraction were allocated to 2 groups: postextraction sockets grafted with bovine bone mineral (bbm), and naturally healing sockets (nat)...
September 14, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28905422/the-role-of-primary-care-for-the-oral-health-of-rural-and-urban-older-adults
#15
Julia T Caldwell, Haena Lee, Kathleen A Cagney
CONTEXT: Rural populations often have restricted access to dental care and poor oral health. These problems may disproportionately affect older blacks in rural areas. Little is known about how access to primary health care may improve the oral health of rural seniors. PURPOSE: This study examines whether the relationship between having a usual source of health care and oral health varies for white and black older adults in rural and urban areas in the United States...
September 14, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28905412/long-term-treatment-costs-for-aggressive-periodontitis-in-a-german-population
#16
Falk Schwendicke, Anne Sophie Biffar, Christian Graetz
AIM: This study assessed the long-term annual costs for treating aggressive periodontitis (AgP) patients. METHODS: A cohort of compliant AgP patients was retrospectively evaluated. Costs for active periodontal therapy (APT, including scaling and root planning, open flap debridement, root resections, but not pocket-elimination or regenerative surgery) and supportive periodontal therapy (SPT, including also costs for restorative, endodontic, prosthetic and surgical treatments) were estimated from a mixed payer-perspective in Germany...
September 14, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28903981/serotonin-drives-predatory-feeding-behavior-via-synchronous-feeding-rhythms-in-the-nematode-pristionchus-pacificus
#17
Misako Okumura, Martin Wilecki, Ralf J Sommer
Feeding behaviors in a wide range of animals are regulated by the neurotransmitter serotonin, although the exact neural circuits and associated mechanism are often unknown. The nematode Pristionchus pacificus can kill other nematodes by opening prey cuticles with movable teeth. Previous studies showed that exogenous serotonin treatment induces a predatory-like tooth movement and slower pharyngeal pumping in the absence of prey, however, physiological functions of serotonin during predation and other behaviors in P...
September 13, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28903524/pediatric-dental-clinic-associated-outbreak-of-mycobacterium-abscessus-infection
#18
Lindsay A Hatzenbuehler, Melissa Tobin-D'Angelo, Cherie Drenzek, Gianna Peralta, Lisa C Cranmer, Evan J Anderson, Sarah S Milla, Shelly Abramowicz, Jumi Yi, Joseph Hilinski, Roy Rajan, Matthew K Whitley, Verlia Gower, Frank Berkowitz, Craig A Shapiro, Joseph K Williams, Paula Harmon, Andi L Shane
Background: Mycobacterium abscessus is an uncommon cause of invasive odontogenic infection. Methods: M abscessus-associated odontogenic infections occurred in a group of children after they each underwent a pulpotomy. A probable case-child was defined as a child with facial or neck swelling and biopsy-confirmed granulomatous inflammation after a pulpotomy between October 1, 2013, and September 30, 2015. M abscessus was isolated by culture in confirmed case-children...
September 1, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28902420/one-piece-zirconia-oral-implants-for-single-tooth-replacement-three-year-results-from-a-long-term-prospective-cohort-study
#19
Ralf-Joachim Kohal, Benedikt Christopher Spies, Annalena Bauer, Frank Butz
AIM: This 3-year report of a prospective long-term cohort investigation aimed to evaluate the clinical and radiographic outcomes of a one-piece zirconia oral implant for single tooth replacement. MATERIALS AND METHODS: 65 patients received a 1-stage implant surgery with immediate temporization. Standardized radiographs were taken at implant insertion, after 1 year, and after 3 years to monitor peri-implant bone levels. A univariate analysis of the association of different baseline parameters on marginal bone loss from implant insertion to 36 months was performed...
September 13, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28894668/mucosal-perfusion-preservation-by-a-novel-shapeable-tissue-expander-for-oral-reconstruction
#20
Daria Barwinska, John Garner, Darrell D Davidson, Todd G Cook, George J Eckert, Sunil S Tholpady, Keith L March, Kinam Park, Clark T Barco
BACKGROUND: There are few methods for expanding oral mucosa, and these often cause complications such as tissue necrosis and expander eruption. This study examines mucosal blood perfusion following insertion of a novel shapeable hydrogel tissue expander (HTE). The canine model used subgingival insertion of HTE following tooth extraction and alveolar bone reduction. The primary goal of this study was to gain understanding of epithelial perfusion and reparative responses of gingival mucosa during HTE expansion...
August 2017: Plastic and Reconstructive Surgery. Global Open
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