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Pulp biology

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https://www.readbyqxmd.com/read/28911645/antibiofilm-activity-of-cashew-juice-pulp-against-staphylococcus-aureus-high-performance-liquid-chromatography-diode-array-detection-and-gas-chromatography-mass-spectrometry-analyses-and-interference-on-antimicrobial-drugs
#1
Marcus V Dias-Souza, Renan M Dos Santos, Ezequias P de Siqueira, Pedro H Ferreira-Marçal
The epidemiology of Staphylococcus aureus infections has evolved in recent years, as this species is a major Gram-positive pathogen associated with healthcare services. The antimicrobial resistance of this species raises an urgent need for new treatment strategies. Fruits play important nutritional and economic roles in society, but their biological and pharmacological features are poorly explored when compared to nonedible parts of plants such as barks and leaves. In this study, we show that the cashew apple juice [cashew juice pulp (CJP)] extract is active against the planktonic cells of S...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28899675/kraft-lignin-biorefinery-a-proposal
#2
Jianjun Hu, Quanguo Zhang, Duu-Jong Lee
Lignin is a huge energy and carbon reserve but owing to its highly biologically recalcitrant nature it is commonly regarded as a waste in lignocellulosic biomass biorefinery. To realize the lignin biorefinery, it is proposed to use Kraft lignin, isolated from black liquor from Kraft pulping mills, as starting material to be fragmented by fast pyrolysis or selective catalysis to aromatic sub-units and to be post-refining with additional cleavage reaction and separation/purification as commodity aromatics pool in chemical industries...
September 1, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28891221/comparative-analysis-of-the-biological-effects-of-the-endodontic-bioactive-cements-mta-angelus-mta-repair-hp-and-neomta-plus-on-human-dental-pulp-stem-cells
#3
C J Tomás-Catalá, M Collado-González, D García-Bernal, R E Oñate-Sánchez, L Forner, C Llena, A Lozano, P Castelo-Baz, J M Moraleda, F J Rodríguez-Lozano
AIM: To evaluate the biological effects in vitro of MTA Angelus (MTA-Ang; Angelus, Londrina, PR, Brazil), MTA Repair HP (MTA-HP; Angelus,) and NeoMTA Plus (NeoMTA-P; Avalon Biomed Inc, Bradenton, FL, USA) on human dental pulp stem cells (hDPSCs). METHODOLOGY: Cell viability and cell migration assays were performed using eluates of each material. To evaluate cell morphology and cell attachment to the different materials, hDPSCs were directly seeded onto the material surfaces and analyzed by immunocytofluorescence and scanning electron microscopy, respectively...
September 11, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28887649/metal-concentrations-and-responses-of-chironomid-larvae-exposed-to-thailand-pulp-and-paper-mill-effluent
#4
Natsima Tokhun, Chuleemas Boonthai Iwai, Barry N Noller
Pulp and paper mills (PPM) may discharge insufficiently treated waste into rivers and give rise to serious effects with aquatic life. This study investigated the biological response of the chironomid (Chironomus javanus, Kieffer) when exposed to PPM effluent. Effluent concentrations of BOD, COD, TKN, TS, Cr, Cu, Pb and Zn were high. Cd and Cr concentrations in chironomid were the most accumulated. Whole effluent toxicity on the chironomid test organism was significant as expressed by the percent survival and decreased with increasing concentration...
September 8, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28885570/litchi-chinensis-as-a-functional-food-and-a-source-of-antitumor-compounds-an-overview-and-a-description-of-biochemical-pathways
#5
REVIEW
Sonia Emanuele, Marianna Lauricella, Giuseppe Calvaruso, Antonella D'Anneo, Michela Giuliano
Litchi is a tasty fruit that is commercially grown for food consumption and nutritional benefits in various parts of the world. Due to its biological activities, the fruit is becoming increasingly known and deserves attention not only for its edible part, the pulp, but also for its peel and seed that contain beneficial substances with antioxidant, cancer preventive, antimicrobial, and anti-inflammatory functions. Although literature demonstrates the biological activity of Litchi components in reducing tumor cell viability in in vitro or in vivo models, data about the biochemical mechanisms responsible for these effects are quite fragmentary...
September 8, 2017: Nutrients
https://www.readbyqxmd.com/read/28883989/osteoinductive-effects-of-preoperative-dexamethasone-in-human-dental-pulp-stem-cells-primary-culture
#6
Rani da Cunha Moretti, Monica Talarico Duailibi, Paulo Oliveira Martins, Jennifer Adriane Dos Santos, Silvio Eduardo Duailibi
AIM: The use of dexamethasone (DEX) in mesenchymal cell culture induces osteoblastic differentiation and, consequently, formation of mineralized tissues. Tissue engineering proposes the development of therapeutic strategies aimed at structural and functional regeneration of biological tissues. In this sense, cell characterization in vitro is critical to ensure the development of such techniques. Our objective was to evaluate the osteoinductive effect of DEX administered as a preoperative medication in primary cell culture of human dental pulp stem cell...
August 2017: Future Science OA
https://www.readbyqxmd.com/read/28860516/indirect-immobilized-jagged1-suppresses-cell-cycle-progression-and-induces-odonto-osteogenic-differentiation-in-human-dental-pulp-cells
#7
Jeeranan Manokawinchoke, Praphawi Nattasit, Tanutchaporn Thongngam, Prasit Pavasant, Kevin A Tompkins, Hiroshi Egusa, Thanaphum Osathanon
Notch signaling regulates diverse biological processes in dental pulp tissue. The present study investigated the response of human dental pulp cells (hDPs) to the indirect immobilized Notch ligand Jagged1 in vitro. The indirect immobilized Jagged1 effectively activated Notch signaling in hDPs as confirmed by the upregulation of HES1 and HEY1 expression. Differential gene expression profiling using an RNA sequencing technique revealed that the indirect immobilized Jagged1 upregulated genes were mainly involved in extracellular matrix organization, disease, and signal transduction...
August 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28844305/regenerative-endodontics-for-adult-patients
#8
Ling He, Sahng G Kim, Qimei Gong, Juan Zhong, Sainan Wang, Xuedong Zhou, Ling Ye, Junqi Ling, Jeremy J Mao
The goal of endodontics is to save teeth. Since inception, endodontic treatments are performed to obturate disinfected root canals with inert materials such as gutta-percha. Although teeth can be saved after successful endodontic treatments, they are devitalized and therefore susceptible to reinfections and fractures. The American Association of Endodontists (AAE) has made a tremendous effort to revitalize disinfected immature permanent teeth in children and adolescents with diagnoses including pulp necrosis or apical periodontitis...
September 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28842333/a-theranostic-dental-pulp-capping-agent-with-improved-mri-and-ct-contrast-and-biological-properties
#9
S Mastrogiacomo, N Güvener, W Dou, H S Alghamdi, W A Camargo, J G O Cremers, P J A Borm, A Heerschap, E Oosterwijk, J A Jansen, X F Walboomers
Different materials have been used for vital dental pulp treatment. Preferably a pulp capping agent should show appropriate biological performance, excellent handling properties, and a good imaging contrast. These features can be delivered into a single material through the combination of therapeutic and diagnostic agents (i.e. theranostic). Calcium phosphate based composites (CPCs) are potentially ideal candidate for pulp treatment, although poor imaging contrast and poor dentino-inductive properties are limiting their clinical use...
August 22, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28842267/medicinal-properties-of-mangosteen-garcinia-mangostana-l-a-comprehensive-update
#10
REVIEW
Berenice Ovalle-Magallanes, Dianelena Eugenio-Pérez, José Pedraza-Chaverri
Garcinia mangostana L. (Clusiaceae) is a tropical tree native to Southeast Asia known as mangosteen which fruits possess a distinctive and pleasant taste that has granted them the epithet of "queen of the fruits". The seeds and pericarps of the fruit have a long history of use in the traditional medicinal practices of the region, and beverages containing mangosteen pulp and pericarps are sold worldwide as nutritional supplements. The main phytochemicals present in the species are isoprenylated xanthones, a class of secondary metabolites with multiple reports of biological effects, such as antioxidant, pro-apoptotic, anti-proliferative, antinociceptive, anti-inflammatory, neuroprotective, hypoglycemic and anti-obesity...
August 24, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28821996/mesenchymal-stromal-stem-cell-separation-methods-concise-review
#11
REVIEW
Andreas Nicodemou, Lubos Danisovic
Mesenchymal stem (stromal) cells (MSCs) possess unique biological characteristics such as plasticity, long term self-renewal, secretion of various bioactive molecules and ability of active migration to the diseased tissues that make them unique tool for regenerative medicine, nowadays. Until now MSCs were successfully derived from many tissue sources including bone marrow, umbilical cord, adipose tissue, dental pulp etc. The crucial step prior to their in vitro expansion, banking or potential clinical application is their separation...
August 18, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28821734/transcriptional-transitions-in-alphonso-mango-mangifera-indica-l-during-fruit-development-and-ripening-explain-its-distinct-aroma-and-shelf-life-characteristics
#12
Ashish B Deshpande, Krishanpal Anamika, Vineet Jha, Hemangi G Chidley, Pranjali S Oak, Narendra Y Kadoo, Keshav H Pujari, Ashok P Giri, Vidya S Gupta
Alphonso is known as the "King of mangos" due to its unique flavor, attractive color, low fiber pulp and long shelf life. We analyzed the transcriptome of Alphonso mango through Illumina sequencing from seven stages of fruit development and ripening as well as flower. Total transcriptome data from these stages ranged between 65 and 143 Mb. Importantly, 20,755 unique transcripts were annotated and 4,611 were assigned enzyme commission numbers, which encoded 142 biological pathways. These included ethylene and flavor related secondary metabolite biosynthesis pathways, as well as those involved in metabolism of starch, sucrose, amino acids and fatty acids...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28814182/regenerative-endodontics
#13
Kristina Feigin, Bonnie Shope
Regenerative endodontics has been defined as "biologically based procedure designed to replace damaged structures, including dentin and root structures, as well as cells of the pulp-dentin complex." This is an exciting and rapidly evolving field of human endodontics for the treatment of immature permanent teeth with infected root canal systems. These procedures have shown to be able not only to resolve pain and apical periodontitis but continued root development, thus increasing the thickness and strength of the previously thin and fracture-prone roots...
September 2017: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28812219/eminent-sources-of-adult-mesenchymal-stem-cells-and-their-therapeutic-imminence
#14
REVIEW
Dannie Macrin, Joel P Joseph, Aruthra Arumugam Pillai, Arikketh Devi
In the recent times, stem cell biology has garnered the attention of the scientific fraternity and the general public alike due to the immense therapeutic potential that it holds in the field of regenerative medicine. A breakthrough in this direction came with the isolation of stem cells from human embryo and their differentiation into cell types of all three germ layers. However, the isolation of mesenchymal stem cells from adult tissues proved to be advantageous over embryonic stem cells due to the ethical and immunological naivety...
August 15, 2017: Stem Cell Reviews
https://www.readbyqxmd.com/read/28782906/differentiation-of-human-dental-pulp-stem-cells-into-neuronal-by-resveratrol
#15
Ya-Wei Geng, Zhen Zhang, Ming-Yue Liu, Wei-Ping Hu
Dental pulp stem cells (DPSCs) have been proposed as a promising source of stem cells in nerve regeneration due to their close embryonic origin and ease of harvest. Resveratrol (RSV) is a natural polyphenolic and possesses many biological functions such as anti-inflammatory activity and protection against atherosclerosis and neuroprotective activities. There is increasing evidence showing that RSV plays a pivotal role in neuron protection and neuronal differentiation. In this study, we isolated DPSCs from impacted third molars and investigated whether RSV induces neuronal differentiation of DPSCs...
August 7, 2017: Cell Biology International
https://www.readbyqxmd.com/read/28782711/cough-sensors-from-dental-pulp
#16
REVIEW
Lorcan P McGarvey, Rebecca Clarke, Fionnuala T Lundy
Mechanisms which alter sensory neural activity, in particular those rendering nerves hyper-responsive have been implicated in the pathophysiology of common clinical syndromes including chronic cough, itch and pain. However, experimental study of human sensory neurons is challenging because the cell bodies of peripheral neurons are housed in neuronal ganglia which are not accessible using peripheral biopsy techniques. While important advances have been made from studies conducted in animal models, there are interspecies differences...
August 4, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28776281/expression-of-optineurin-isolated-from-rat-injured-dental-pulp-and-the-effects-on-inflammatory-signals-in-normal-rat-kidney-cells
#17
Kyoko Senoo, Keisuke Yamashairo, Tadashi Yamamoto, Fumio Myokai, Mari Kawamura, Shogo Takashiba
We previously isolated rat 14.7K-interacting protein-2 (rFIP-2) from the rat-wounded pulp. The protein, homologous to human FIP-2, is known as optineurin and was initially identified as a novel tumor necrosis factor-α (TNF-α)-inducible protein, and more recently, as an autophagy receptor. However, the biological role of optineurin in dental pulp remains elusive. We hypothesized that optineurin has a crucial role in regulating molecular processes during pulp inflammatory responses induced by TNF-α. We examined the kinetics of optineurin expression in pulp inflammation...
August 3, 2017: Odontology
https://www.readbyqxmd.com/read/28773189/evaluation-of-3d-printed-polycaprolactone-scaffolds-coated-with-freeze-dried-platelet-rich-plasma-for-bone-regeneration
#18
Junda Li, Meilin Chen, Xiaoying Wei, Yishan Hao, Jinming Wang
Three-dimensional printing is one of the most promising techniques for the manufacturing of scaffolds for bone tissue engineering. However, a pure scaffold is limited by its biological properties. Platelet-rich plasma (PRP) has been shown to have the potential to improve the osteogenic effect. In this study, we improved the biological properties of scaffolds by coating 3D-printed polycaprolactone (PCL) scaffolds with freeze-dried and traditionally prepared PRP, and we evaluated these scaffolds through in vitro and in vivo experiments...
July 19, 2017: Materials
https://www.readbyqxmd.com/read/28764046/stability-of-bioactive-compounds-in-buti%C3%A3-butia-odorata-fruit-pulp-and-nectar
#19
Jessica Fernanda Hoffmann, Giovana Paula Zandoná, Priscila Silveira Dos Santos, Camila Müller Dallmann, Francine Bonemann Madruga, Cesar Valmor Rombaldi, Fábio Clasen Chaves
Butia odorata is a palm tree native to southern Brazil whose fruit (known as butiá) and leaves are used to make many food products and crafts. Butiá contain several biologically active compounds with potential health benefits. However, processing conditions can alter quality attributes including bioactive compound content. This study evaluated the stability of bioactive compounds in butiá pulp upon pasteurization, during 12months of frozen storage, and in butiá nectar after a 3-month storage period. Pulp pasteurization resulted in a reduction in phenolic, flavonoid, carotenoid, and ascorbic acid contents...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28758221/biological-medicinal-and-toxicological-significance-of-eucalyptus-leaf-essential-oil-a-review
#20
REVIEW
Ashok K Dhakad, Vijay V Pandey, Sobia Beg, Janhvi M Rawat
The genus Eucalyptus L'Heritier comprises about 900 species, of which more than 300 species contain volatile essential oil in their leaves. About 20 species, within these, have a high content of 1,8-cineole (more than 70 %), commercially used for the production of essential oils in pharmaceutical and cosmetic industries. However, Eucalyptus is extensively planted for pulp, plywood, solid wood production but its leaf aromatic oil has astounding widespread biological activities including antimicrobial, antiseptic, antioxidant, chemotherapy agent, respiratory and gastrointestinal disorders treatment, wound healing, and insecticidal/insect repellent, herbicidal, acaricidal, nematicidal, and perfumes, soap making and grease remover...
July 31, 2017: Journal of the Science of Food and Agriculture
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