Samuel R Schnittman, Márton Kolossváry, Gabriele Beck-Engeser, Kathleen V Fitch, Gabrielle C Ambayec, Robin M Nance, Markella V Zanni, Marissa Diggs, Fay Chan, Sara McCallum, Mabel Toribio, Laura Bamford, Carl J Fichtenbaum, Joseph J Eron, Jeffrey M Jacobson, Kenneth H Mayer, Carlos Malvestutto, Gerald S Bloomfield, Richard D Moore, Triin Umbleja, Michael S Saag, Judith A Aberg, Judith S Currier, Joseph A C Delaney, Jeffrey N Martin, Michael T Lu, Pamela S Douglas, Heather J Ribaudo, Heidi M Crane, Peter W Hunt, Steven K Grinspoon
Plasma vascular endothelial growth factor (VEGF) coreceptor neuropilin-1 (NRP-1) had the largest association with coronary plaque in the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) proteomics analysis. With little known about NRP-1 in people with human immunodeficiency virus (PWH), we explored its relation to other proteins in REPRIEVE and validated our findings through a Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) case-cohort study by assessing its relation to host factors and incident cardiovascular disease and cancer...
October 2023: Open Forum Infectious Diseases